LOCUS       DAVMCG010000001       119660 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVMCG010000001 DAVMCG010000000
VERSION     DAVMCG010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 119660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 119660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..119660
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.001"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            175..357
                     /locus_tag="VYP66_000001"
     CDS             175..357
                     /locus_tag="VYP66_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1849631.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            302..1151
                     /locus_tag="VYP66_000002"
     CDS             join(302..715,717..1151)
                     /locus_tag="VYP66_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1849632.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDARFKRLVGVQRTTFEEML
                     AVLKTTYQLKHAKGGRKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLIRRSQ
                     WVEATLVQSGVTISRTPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIV
                     TSQGRIVSLDITVNYCHDMKLFKMSRRNIGQAGKILADSGYQGPMKIYPQAQTPRKSS
                     KLKPLIAEDKAYNHALSKERSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLIAGII
                     NHELGF"
     gene            complement(1223..1585)
                     /locus_tag="VYP66_000003"
     CDS             complement(1223..1585)
                     /locus_tag="VYP66_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849633.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHTFFMDNVEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(1963..3843)
                     /locus_tag="VYP66_000004"
     CDS             complement(1963..3843)
                     /locus_tag="VYP66_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1849634.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEFYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(3837..4706)
                     /locus_tag="VYP66_000005"
     CDS             complement(3837..4706)
                     /locus_tag="VYP66_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1849635.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(4790..7435)
                     /locus_tag="VYP66_000006"
     CDS             complement(4790..7435)
                     /locus_tag="VYP66_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1849636.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(7526..8806)
                     /locus_tag="VYP66_000007"
     CDS             complement(7526..8806)
                     /locus_tag="VYP66_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1849637.1"
                     /translation="MVYSKEIVREWLDEVAERAKDYPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            8978..11062
                     /locus_tag="VYP66_000008"
     CDS             8978..11062
                     /locus_tag="VYP66_000008"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1849638.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALQQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLKTASKADP
                     LGINGRHGLAQYQELDYLSTDHHESVSHTLDYAYSDFCIANCAKKLKNIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGISLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(11102..12781)
                     /locus_tag="VYP66_000009"
     CDS             complement(11102..12781)
                     /locus_tag="VYP66_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1849639.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSMPLLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            13537..14766
                     /gene="arcA"
                     /locus_tag="VYP66_000010"
     CDS             13537..14766
                     /gene="arcA"
                     /locus_tag="VYP66_000010"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1849640.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            14824..15840
                     /gene="argF"
                     /locus_tag="VYP66_000011"
     CDS             14824..15840
                     /gene="argF"
                     /locus_tag="VYP66_000011"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1849641.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            16005..16952
                     /gene="arcC"
                     /locus_tag="VYP66_000012"
     CDS             16005..16952
                     /gene="arcC"
                     /locus_tag="VYP66_000012"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1849642.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            17161..18672
                     /locus_tag="VYP66_000013"
     CDS             17161..18672
                     /locus_tag="VYP66_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1849643.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            18694..20025
                     /locus_tag="VYP66_000014"
     CDS             18694..20025
                     /locus_tag="VYP66_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1849644.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNDLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(20432..20722)
                     /locus_tag="VYP66_000015"
     CDS             complement(20432..20722)
                     /locus_tag="VYP66_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849645.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDKVAQI"
     gene            complement(20710..20961)
                     /locus_tag="VYP66_000016"
     CDS             complement(20710..20961)
                     /locus_tag="VYP66_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1849646.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            21165..21242
                     /locus_tag="VYP66_000017"
                     /pseudo
     CDS             21165..21242
                     /locus_tag="VYP66_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21360..22244)
                     /locus_tag="VYP66_000018"
     CDS             complement(21360..22244)
                     /locus_tag="VYP66_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1849647.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(22389..23540)
                     /locus_tag="VYP66_000019"
     CDS             complement(22389..23540)
                     /locus_tag="VYP66_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1849648.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(23686..25452)
                     /locus_tag="VYP66_000020"
     CDS             complement(23686..25452)
                     /locus_tag="VYP66_000020"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1849649.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(25465..26193)
                     /locus_tag="VYP66_000021"
     CDS             complement(25465..26193)
                     /locus_tag="VYP66_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HEV1849650.1"
                     /translation="MSQDEKLIREQICDVCHKMWQLGWVAANDGNVSVRLDEDTILAT
                     PTGISKSFITPEKLVKLNLKGEILEAEGDYCPSSEIKMHIRCYEEREDVRSVVHAHPP
                     IATGFALAHIPLDTYSLIESAIVVGAIPITPFGVPSTMEVPEAITPYLPDHDVMLLEN
                     HGALTVGSDVITAYYRMETLELVAKTTFHGRMLLSTKGIEEQEIARPTLERLFSMREN
                     YKVTGRHPGYRKYNGDGSMKETEK"
     gene            complement(26208..29225)
                     /locus_tag="VYP66_000022"
     CDS             complement(26208..29225)
                     /locus_tag="VYP66_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEV1849651.1"
                     /translation="MESKKIAKQILIATAVLTSFLGSNLVYADVVQSNSNNRASTETA
                     RVTGNNLEKLITKDKEIDKEMTYLSDMDWSSATHGDIDKTKTVQKDAPFTTGNKGEHT
                     KISLLTSDDKVKYFDKGIGTVADSPSVISYDISGQGFEKFETYIGIDQSANSSRSDHA
                     VVDRIEIEIDGKVVYSSSVTNPEGFRYNTQAQFISVTIPQNAKKISLKSFAGEHTWGD
                     EVVFADAKLIKTVSTQTITPDLLNKGINGGVYLSDLEWVDATHGDDDKSKTVQKDKPF
                     TPGNNGSNNKIKLLIDGKEVEFNKGLGTVASNPSSIKYDVSGANVTRFISYVGIDRSA
                     NHLNSDYADIQKFEVVADGKVIYSSDSKYPKGIKYDTSAFLVDVEIPKDTQTIELKSY
                     SGKHTWADELVLGGALFMANGKFKNPNDWSEVDKRREINNEHPLLMMPLYANGEEFNQ
                     GKYTFWGGDTLTGKWENIPDDLKPYTVIQLHPDDLTKRDGAARDFYEHMLEEAAKYVN
                     PKTGKNEPIPVILTVYTAGNMPYYTSAHWLSTSWIDKMYQKYPNLHGIFSTENYWIWA
                     NDIENKAADYLKVSAKNGGYFIWAEQNNGSAIEKAFGKNGKIAFQKSVDKYWKNLIFM
                     FKNTPAAEGNDSTTESYMKGLWLSNHTYQWGGLMDTWKWYETGKWKLFASGNIGKSQG
                     DRQWLTEPESMLGEEALGVYLNGGVVYNFEHPAYTYGVNNKESLLFSEVIKEFFRYVI
                     AHPAPSKEKVLEDTKVFIHGDYSNKGNGKFFVNVNTDREQTPLYMTGRYNVIPAIPGV
                     LKTDKLKESVSGSRIQIKEITSPEFSSTQARKEYLNKLYPMNYEGDIFAQKLDNRWFV
                     YNYKVNENVKQTGKLKFNSLEMDVEFEPHTYGIFERISNGLKVNLNNFRTNKDSLWSN
                     AQDANQAKKLPQLTKKGAIKWIEEHYIKDTQFGEKRVTKIVLRGIDKLPTIHSLSGTN
                     NSYDQPSLNFDQKNHMVTITINSNGNLEFELHF"
     gene            complement(29236..31452)
                     /locus_tag="VYP66_000023"
     CDS             complement(29236..31452)
                     /locus_tag="VYP66_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1849652.1"
                     /translation="MTIYINKDETVFHLAMKDSSYIFRILENGELQHLHFGKRIHVKE
                     NYNQLMAYEKRGFEVSFSEEFEDIQQSMIQNEYSSYGKGDFRHPAFQVQGMNGSRITT
                     LKYQGFELEKGKNRLNSLPSTFDDIGQCVETLTIILTDSILDLTVRLNYTIFPEYNVL
                     VRNTEFLNNSNNKLTLLKAMSLQLDLPDSQYDFIQFSGAWLRERQLYRTSLRPGIQAI
                     DSLRYSSSPQQNPFFMLSRRETTEHSGEVYGFNFIYSGNFQNMIEVDHFDTARVTVGI
                     NPVEFRFLLNPAESFVTPEAIVIYSDQGMNQMSQQLSDFYRHHLVNPNFSQASRPIIL
                     NSWETFYFDLSTEKILDLAKAAKDLGIELFVLDDGWFGHRKDDKSSLGDWVTDRSRLP
                     EGIGFLADEIHKIGLQFGLWFEPEMISIDSDLYKNHADWTIHLLDREKSVGRNQYVLD
                     LTRQEVVDYLFDSISKIIIKTNLDYIKWDMNRHITDIYSIELDSEQQMEFGHRYILGL
                     YQLLDRLITKFPSVLFESCSSGGGRFDLGLMYYAPQAWTSDDTDPIERLKIQHGTSYG
                     YSPSMMTAHVSISPNEQSGRQTSLDTRTNVAYFSSFGYELDVTRLSVEEKEQVREQIQ
                     FYKKYRSLFQYGDFYRINSPFSCDSASWQVVSKDKCQSILLYAQLNSKLNPGYTRVYF
                     SGLDKDKCYSVSRFDEFFYGDELMNAGIKVSLSNLALCVPEYLTKLFVIEEVVCKY"
     gene            complement(31474..33344)
                     /locus_tag="VYP66_000024"
                     /pseudo
     CDS             complement(31474..33344)
                     /locus_tag="VYP66_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863627.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-acetylgalactosaminidase"
     gene            complement(33350..34669)
                     /locus_tag="VYP66_000025"
     CDS             complement(33350..34669)
                     /locus_tag="VYP66_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1849653.1"
                     /translation="MKHTLETINSRTQWFREARFGMFIHWGLYSIPGKGEWIRSHQKL
                     SIEDYEPYFRAFDPKEYNPREWAKQAKAAGMKYMVLTAKHHDGFCLFDSKFTDYKATN
                     TPAGRDLVKEFVDAVRAEGLKVGLYFSLIDWHHPDFPKYADLNHPMRGNEAYRDEKIN
                     FDRYLEYLHNQVKEIVTGYGQIDILWFDYSYEDMVGEKWGASKLIDMVRHYQPNVIVD
                     NRLETSGEGFGSIVTDEITSYAGDFVSPEQIVPHEGIRNFKGEPVPWELCLTMNNNWA
                     YNPTDYLYKSSQTLIRKLVECVSKNGNMILNVGPDALGRINDSSKKILDNFHRWMSRN
                     GEAIYGCSGDENLPKPDWGYYTRNGNTVYAHVFEQPIGPLALLGISKENVKRMSFLHD
                     GSEVKISESWTTNAYKGICFAQFGEVPHFTYPLPDLIDSVIKIELRE"
     gene            complement(34666..35505)
                     /locus_tag="VYP66_000026"
     CDS             complement(34666..35505)
                     /locus_tag="VYP66_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1849654.1"
                     /translation="MNTHINGISKKGKVLIYGYMLLTILISIFPIAWIFLSSLKADPM
                     KNPGISLPIDFTLEGYINVFTKLHVFTYFWNSFKVVSISVIISIVMISMSSYVIARME
                     FRGKKLVTSMLYSTLFIPATAMTFPVYRLVNELGIYNTPVALILVYSCSGIAMSFFII
                     KNYFEIIPKELEEAAEIDGATYAQTFWKVMLPIARPGILTAAVLAFINNWNEYYWASM
                     LVIDKNELTVPALLGQFTTSFNTNYNGLFSAIVVIVLPPIILFAFTSKYFIEALGGGA
                     VKG"
     gene            complement(35508..36437)
                     /locus_tag="VYP66_000027"
     CDS             complement(35508..36437)
                     /locus_tag="VYP66_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1849655.1"
                     /translation="MAQKIMSLQNRKNQKRRFIFLFLLPTLICFFLFYFYSVVTIFLT
                     SFAKWDYTNLNTPEFLGFDKLFENYRYVFKEYPFFTEALINSVRWAVIGVIIQVPLAV
                     SVAITLSKKLKGWKISRNLYIVPSIISSAAMGLIFLQIYNPNYGVVNQIIHLFNPSFK
                     DSVLLTPGLNIVAMTGAYIFFAGASTIMILGQIFAIPEEVQEAAILDNITGWRKEWYI
                     TIPMIKGTIKTVSIMAATSGFLLYNEVFFLTNGAAGTKSISFVIRELAVASSRTQYAR
                     ANTIGVIQILGGMLIIVCINILFRERKRLKGGK"
     gene            36503..37111
                     /locus_tag="VYP66_000028"
     CDS             36503..37111
                     /locus_tag="VYP66_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849656.1"
                     /translation="MTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLD
                     SSTTVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNY
                     DKENSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFY
                     KTGFFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(38240..39745)
                     /gene="adcA"
                     /locus_tag="VYP66_000029"
     CDS             complement(38240..39745)
                     /gene="adcA"
                     /locus_tag="VYP66_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1849657.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(39755..40561)
                     /locus_tag="VYP66_000030"
     CDS             complement(39755..40561)
                     /locus_tag="VYP66_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1849658.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(40554..41258)
                     /locus_tag="VYP66_000031"
     CDS             complement(40554..41258)
                     /locus_tag="VYP66_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1849659.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(41258..41698)
                     /gene="adcR"
                     /locus_tag="VYP66_000032"
     CDS             complement(41258..41698)
                     /gene="adcR"
                     /locus_tag="VYP66_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1849660.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(41853..43121)
                     /gene="dltD"
                     /locus_tag="VYP66_000033"
     CDS             complement(41853..43121)
                     /gene="dltD"
                     /locus_tag="VYP66_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1849661.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNKRFFSKDWATYDGDVKEFQ"
     gene            complement(43114..43353)
                     /gene="dltC"
                     /locus_tag="VYP66_000034"
     CDS             complement(43114..43353)
                     /gene="dltC"
                     /locus_tag="VYP66_000034"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1849662.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(43367..44611)
                     /gene="dltB"
                     /locus_tag="VYP66_000035"
     CDS             complement(43367..44611)
                     /gene="dltB"
                     /locus_tag="VYP66_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1849663.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVIT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(44608..46158)
                     /gene="dltA"
                     /locus_tag="VYP66_000036"
     CDS             complement(44608..46158)
                     /gene="dltA"
                     /locus_tag="VYP66_000036"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1849664.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(46179..46310)
                     /locus_tag="VYP66_000037"
     CDS             complement(46179..46310)
                     /locus_tag="VYP66_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1849665.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(46541..47245)
                     /locus_tag="VYP66_000038"
     CDS             complement(46541..47245)
                     /locus_tag="VYP66_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1849666.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAYLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            complement(47315..49141)
                     /gene="glpO"
                     /locus_tag="VYP66_000039"
     CDS             complement(47315..49141)
                     /gene="glpO"
                     /locus_tag="VYP66_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1849667.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            complement(49183..50691)
                     /gene="glpK"
                     /locus_tag="VYP66_000040"
     CDS             complement(49183..50691)
                     /gene="glpK"
                     /locus_tag="VYP66_000040"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1849668.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            complement(50850..52277)
                     /locus_tag="VYP66_000041"
     CDS             complement(50850..52277)
                     /locus_tag="VYP66_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1849669.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            52442..53314
                     /gene="hslO"
                     /locus_tag="VYP66_000042"
     CDS             52442..53314
                     /gene="hslO"
                     /locus_tag="VYP66_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1849670.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            53301..54281
                     /gene="dusB"
                     /locus_tag="VYP66_000043"
     CDS             53301..54281
                     /gene="dusB"
                     /locus_tag="VYP66_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1849671.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(54511..56418)
                     /gene="pspC"
                     /locus_tag="VYP66_000044"
     CDS             complement(54511..56418)
                     /gene="pspC"
                     /locus_tag="VYP66_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1849672.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGN
                     NSTVTSSGQDISKKYADEVESHLQSILKDVNKNLKKVQHTQNADFNKKLSKIKTKYLY
                     ELNVLEEKSEAELTSKTKETKEELTAAFEQFKKDTLSTEPEKKVAEAKKKVEEAKKKA
                     EDQKEKDRRNYPTITYKTLELEIAESDVEVKKAELELVKVKANEPRDEEKIKQAEAKV
                     ESKQAEATRLKKIKTDREQAEATRLENIKTDREQAEEEAKVKDEPKKRTKRGVLGEPA
                     TPDKKENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKKKAEDQKEEDRRNYP
                     TNTYKTLELEIAESDVEVKKAELELVKEEAKEPRNEEKVKQAKAEVESKQAEATRLEK
                     IKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENPA
                     EQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYF
                     YNTDGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQNNGSW
                     YYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDS
                     YRVNANGEWVN"
     gene            complement(56497..57024)
                     /locus_tag="VYP66_000045"
     CDS             complement(56497..57024)
                     /locus_tag="VYP66_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1849673.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(57107..58447)
                     /gene="hk06"
                     /locus_tag="VYP66_000046"
     CDS             complement(57107..58447)
                     /gene="hk06"
                     /locus_tag="VYP66_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1849674.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(58444..59097)
                     /gene="rr06"
                     /locus_tag="VYP66_000047"
     CDS             complement(58444..59097)
                     /gene="rr06"
                     /locus_tag="VYP66_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1849675.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(59418..61850)
                     /locus_tag="VYP66_000048"
     CDS             complement(59418..61850)
                     /locus_tag="VYP66_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1849676.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(61852..62310)
                     /locus_tag="VYP66_000049"
     CDS             complement(61852..62310)
                     /locus_tag="VYP66_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1849677.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRDLLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            complement(62429..63157)
                     /locus_tag="VYP66_000050"
     CDS             complement(62429..63157)
                     /locus_tag="VYP66_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1849678.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(63157..64164)
                     /locus_tag="VYP66_000051"
     CDS             complement(63157..64164)
                     /locus_tag="VYP66_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1849679.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(64203..64961)
                     /locus_tag="VYP66_000052"
     CDS             complement(64203..64961)
                     /locus_tag="VYP66_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1849680.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            complement(64924..65214)
                     /locus_tag="VYP66_000053"
     CDS             complement(64924..65214)
                     /locus_tag="VYP66_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1849681.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(65285..65387)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(65470..66816)
                     /gene="cbpD"
                     /locus_tag="VYP66_000054"
     CDS             complement(65470..66816)
                     /gene="cbpD"
                     /locus_tag="VYP66_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1849682.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEMPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSASTGGTHYFKTKSAIKPEPLASGTVIDYYYPG
                     EKVHYDQIFEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGENVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSHSSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGLWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     gene            complement(66905..67171)
                     /locus_tag="VYP66_000055"
     CDS             complement(66905..67171)
                     /locus_tag="VYP66_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849683.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(67173..68525)
                     /gene="dnaB"
                     /locus_tag="VYP66_000056"
     CDS             complement(67173..68525)
                     /gene="dnaB"
                     /locus_tag="VYP66_000056"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1849684.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(68569..69021)
                     /gene="rplI"
                     /locus_tag="VYP66_000057"
     CDS             complement(68569..69021)
                     /gene="rplI"
                     /locus_tag="VYP66_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1849685.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(69018..70991)
                     /locus_tag="VYP66_000058"
     CDS             complement(69018..70991)
                     /locus_tag="VYP66_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1849686.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(71127..71675)
                     /gene="raiA"
                     /locus_tag="VYP66_000059"
     CDS             complement(71127..71675)
                     /gene="raiA"
                     /locus_tag="VYP66_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1849687.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(71747..72409)
                     /locus_tag="VYP66_000060"
     CDS             complement(71747..72409)
                     /locus_tag="VYP66_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1849688.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQYCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(72406..73704)
                     /locus_tag="VYP66_000061"
     CDS             complement(72406..73704)
                     /locus_tag="VYP66_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1849689.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            73760..74395
                     /locus_tag="VYP66_000062"
     CDS             73760..74395
                     /locus_tag="VYP66_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1849690.1"
                     /translation="MEFRTIKEDDQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            74680..75600
                     /gene="cysK"
                     /locus_tag="VYP66_000063"
     CDS             74680..75600
                     /gene="cysK"
                     /locus_tag="VYP66_000063"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1849691.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(75797..76195)
                     /locus_tag="VYP66_000064"
     CDS             complement(75797..76195)
                     /locus_tag="VYP66_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1849692.1"
                     /translation="MKAPIPKAPLAHSLGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEIANWHIKASQYYLEPLYNLLRERLLTQSLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            76186..76494
                     /locus_tag="VYP66_000065"
                     /pseudo
     CDS             76186..76494
                     /locus_tag="VYP66_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(76685..76972)
                     /gene="tnpB"
                     /locus_tag="VYP66_000066"
     CDS             complement(76685..76972)
                     /gene="tnpB"
                     /locus_tag="VYP66_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1849693.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(77218..78258)
                     /locus_tag="VYP66_000067"
     CDS             complement(77218..78258)
                     /locus_tag="VYP66_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1849694.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(78337..79116)
                     /gene="rpsB"
                     /locus_tag="VYP66_000068"
     CDS             complement(78337..79116)
                     /gene="rpsB"
                     /locus_tag="VYP66_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1849695.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            complement(79340..80518)
                     /locus_tag="VYP66_000069"
     CDS             complement(79340..80518)
                     /locus_tag="VYP66_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1849696.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            complement(80612..81106)
                     /gene="mreD"
                     /locus_tag="VYP66_000070"
     CDS             complement(80612..81106)
                     /gene="mreD"
                     /locus_tag="VYP66_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1849697.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            complement(81106..81924)
                     /gene="mreC"
                     /locus_tag="VYP66_000071"
     CDS             complement(81106..81924)
                     /gene="mreC"
                     /locus_tag="VYP66_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1849698.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            complement(81983..82777)
                     /locus_tag="VYP66_000072"
     CDS             complement(81983..82777)
                     /locus_tag="VYP66_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1849699.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKSMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            complement(82770..83609)
                     /locus_tag="VYP66_000073"
     CDS             complement(82770..83609)
                     /locus_tag="VYP66_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1849700.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            complement(83594..84421)
                     /locus_tag="VYP66_000074"
     CDS             complement(83594..84421)
                     /locus_tag="VYP66_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1849701.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALDLVGMLDFKKREPARLSGGQKQRVAIAGVVVLRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSHNGYNLPENYLTESELEDKLWELL"
     gene            complement(84418..84963)
                     /gene="pgsA"
                     /locus_tag="VYP66_000075"
     CDS             complement(84418..84963)
                     /gene="pgsA"
                     /locus_tag="VYP66_000075"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1849702.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            complement(84974..85795)
                     /locus_tag="VYP66_000076"
     CDS             complement(84974..85795)
                     /locus_tag="VYP66_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1849703.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            complement(85837..87120)
                     /locus_tag="VYP66_000077"
     CDS             complement(85837..87120)
                     /locus_tag="VYP66_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1849704.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLIVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            complement(87117..88367)
                     /locus_tag="VYP66_000078"
     CDS             complement(87117..88367)
                     /locus_tag="VYP66_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1849705.1"
                     /translation="MELVHGISTHFIQSKKFKTHKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIVKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            88526..88894
                     /gene="yaaA"
                     /locus_tag="VYP66_000079"
     CDS             88526..88894
                     /gene="yaaA"
                     /locus_tag="VYP66_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1849706.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            88897..89994
                     /gene="recF"
                     /locus_tag="VYP66_000080"
     CDS             88897..89994
                     /gene="recF"
                     /locus_tag="VYP66_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1849707.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLNFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSKSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(90045..91523)
                     /gene="guaB"
                     /locus_tag="VYP66_000081"
     CDS             complement(90045..91523)
                     /gene="guaB"
                     /locus_tag="VYP66_000081"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1849708.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(91675..92700)
                     /gene="trpS"
                     /locus_tag="VYP66_000082"
     CDS             complement(91675..92700)
                     /gene="trpS"
                     /locus_tag="VYP66_000082"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1849709.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            92906..94528
                     /locus_tag="VYP66_000083"
     CDS             92906..94528
                     /locus_tag="VYP66_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1849710.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            94590..97142
                     /locus_tag="VYP66_000084"
     CDS             94590..97142
                     /locus_tag="VYP66_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1849711.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(97243..97557)
                     /locus_tag="VYP66_000085"
     CDS             complement(97243..97557)
                     /locus_tag="VYP66_000085"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1849712.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(97585..97923)
                     /locus_tag="VYP66_000086"
     CDS             complement(97585..97923)
                     /locus_tag="VYP66_000086"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849713.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFFAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            complement(98008..98775)
                     /locus_tag="VYP66_000087"
     CDS             complement(98008..98775)
                     /locus_tag="VYP66_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEV1849714.1"
                     /translation="MIGISLIPALYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSKKTTTLSNI
                     QSTAAYQSLTSEQQTGISDSVSQNSTDSIQSAQSIVALVQGLQGSLENLQNQSSNLST
                     LKNQANQVLPITSTSLIGLSSGLTEIQGAVTSKLVPASQLIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            98953..99495
                     /locus_tag="VYP66_000088"
     CDS             98953..99495
                     /locus_tag="VYP66_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1849715.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(99536..99609)
                     /locus_tag="VYP66_000089"
     tRNA            complement(99536..99609)
                     /locus_tag="VYP66_000089"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(99573..99575),aa:Asn,seq:gtt)
     gene            complement(99615..99686)
                     /locus_tag="VYP66_000090"
     tRNA            complement(99615..99686)
                     /locus_tag="VYP66_000090"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(99651..99653),aa:Glu,seq:ttc)
     gene            complement(99738..100490)
                     /locus_tag="VYP66_000091"
     CDS             complement(99738..100490)
                     /locus_tag="VYP66_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1849716.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(100487..101812)
                     /locus_tag="VYP66_000092"
     CDS             complement(100487..101812)
                     /locus_tag="VYP66_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1849717.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            complement(101833..101958)
                     /gene="comC"
                     /locus_tag="VYP66_000093"
     CDS             complement(101833..101958)
                     /gene="comC"
                     /locus_tag="VYP66_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1849718.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            complement(102123..102196)
                     /locus_tag="VYP66_000094"
     tRNA            complement(102123..102196)
                     /locus_tag="VYP66_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(102160..102162),aa:Arg,seq:tct)
     gene            complement(102240..102719)
                     /gene="rlmH"
                     /locus_tag="VYP66_000095"
     CDS             complement(102240..102719)
                     /gene="rlmH"
                     /locus_tag="VYP66_000095"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1849719.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            102902..104083
                     /locus_tag="VYP66_000096"
     CDS             102902..104083
                     /locus_tag="VYP66_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1849720.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            104141..104899
                     /locus_tag="VYP66_000097"
     CDS             104141..104899
                     /locus_tag="VYP66_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1849721.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            105112..106473
                     /gene="dnaA"
                     /locus_tag="VYP66_000098"
     CDS             105112..106473
                     /gene="dnaA"
                     /locus_tag="VYP66_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1849722.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            106632..107768
                     /gene="dnaN"
                     /locus_tag="VYP66_000099"
     CDS             106632..107768
                     /gene="dnaN"
                     /locus_tag="VYP66_000099"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1849723.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            107833..108027
                     /locus_tag="VYP66_000100"
     CDS             107833..108027
                     /locus_tag="VYP66_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1849724.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            108111..109226
                     /gene="ychF"
                     /locus_tag="VYP66_000101"
     CDS             108111..109226
                     /gene="ychF"
                     /locus_tag="VYP66_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1849725.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRASYHLLGLGTYFTAGEKEVRAWTFKRGMKATQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            109297..109866
                     /locus_tag="VYP66_000102"
     CDS             109297..109866
                     /locus_tag="VYP66_000102"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1849726.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            109867..113376
                     /gene="mfd"
                     /locus_tag="VYP66_000103"
     CDS             109867..113376
                     /gene="mfd"
                     /locus_tag="VYP66_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1849727.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKVPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASHPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSCLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIVENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            113434..113700
                     /locus_tag="VYP66_000104"
     CDS             113434..113700
                     /locus_tag="VYP66_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1849728.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            113693..114061
                     /locus_tag="VYP66_000105"
     CDS             113693..114061
                     /locus_tag="VYP66_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1849729.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            114181..115449
                     /locus_tag="VYP66_000106"
     CDS             114181..115449
                     /locus_tag="VYP66_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1849730.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            115446..116723
                     /gene="tilS"
                     /locus_tag="VYP66_000107"
     CDS             115446..116723
                     /gene="tilS"
                     /locus_tag="VYP66_000107"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1849731.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFKKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRNAILGISNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            116727..117269
                     /gene="hpt"
                     /locus_tag="VYP66_000108"
     CDS             116727..117269
                     /gene="hpt"
                     /locus_tag="VYP66_000108"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1849732.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            117285..119243
                     /gene="ftsH"
                     /locus_tag="VYP66_000109"
     CDS             117285..119243
                     /gene="ftsH"
                     /locus_tag="VYP66_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1849733.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            119365..>119660
                     /locus_tag="VYP66_000110"
     CDS             119365..>119660
                     /locus_tag="VYP66_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1849734.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEG"
BASE COUNT        36836 a        24853 c        21194 g        36777 t
ORIGIN      
        1 aagtcaagga aaattaaccc actttaattt cttttttaac ccgggttaaa aaagaaatta
       61 aagtgggtta aaaaagaaat taactgagta aaaactctcg aaattcaatt cgctatatta
      121 tcactcaact tgaacaaata ccagaaccac aaaaaacaga tgtaaaggaa aaatatggac
      181 ttaaaatttg aaggggttga tttagaatac aaaaaagcta aaaacaatct tccagagtct
      241 ttctgggaaa cctactcagc atttgcaaat acaaatggcg ggaaaataat tctcgggata
      301 gatgaaaaaa acattgacac ctaccaaaga gtcaatagac tccctgcgaa attatgaagc
      361 aagtaaacaa ctaaccgatg cacgatttaa gcgtcttgtt ggtgttcagc gcaccacttt
      421 tgaagagatg ttagctgtgt taaaaacaac ttatcaactt aaacacgcaa aaggtggacg
      481 aaaacctaaa ttaagcctag aagaccttct tatggccact cttcaatatg tgcgagaata
      541 ccgcacttat gaagaaattg cggctgattt tggtattcac gaaagcaact taatccgtcg
      601 gagccaatgg gttgaagcaa ctcttgttca aagtggtgtt acgatttcaa gaactcctct
      661 cagttctgag gacacggtaa tgattgatgc gacggaagta aaaatcaatc gccctaaaaa
      721 aagaactagc gaatgattct ggtaaaaaga aatgccacgc tatgaaggct caagcgattg
      781 tcacaagtca agggagaatt gtttctttgg atatcactgt gaactattgt catgatatga
      841 agttgttcaa aatgagtcgc agaaatatcg gacaagctgg taaaatcttg gctgacagtg
      901 gttatcaagg gcccatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
      961 tcaagccgct aatagctgaa gataaagcct ataaccatgc gctatctaag gagagaagca
     1021 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat attttcaaca acctatcgaa
     1081 atcatcgtaa acgcttcgga ttacgaatga atttgattgc tggtattatc aatcatgaac
     1141 taggattcta gttttgcagg aagtctattg aaatactaag cctacacaca gactgattcc
     1201 aattgttttt tagatttcaa ttttaccatt cttcatagtc aaaaccatca taatctggat
     1261 attgttctgg cgacgttcca accgaacgta cgagataagc ttcttcgtcc tctgtctcga
     1321 tttctctcag cacttggcat tcaaaacgcc attcatcacc gaagtcgaaa ataaacttaa
     1381 atttttgttt gacacttagg ctatccagat agacattttc tgtgtaacgt tcttcaacat
     1441 cgtcactaac aaagctaaga aagtaagaat ctgcatgact ccactcaaca ttatccatga
     1501 aaaatgtgtg agcatgatca tttgcaaaat caaaactcca taaaatcaca tctgctagtt
     1561 ccgctaacgt ttttgttttt ggaatctata tatgtcggta gcaacctttt ttaaatttga
     1621 cggaaatgat ccaagcttct acagatgctg gcttttcagc ttctatttct tgttttacta
     1681 attttaagtg tagcataata cctccaattg ctcatcgata gaattgctct taggaaacat
     1741 tcactttctg ctattttatc ataagtttgt ctaactgtag catttgaaac cagataattc
     1801 ttctgtttca cgcgaaacac cctgcgccaa gcaaggtgtt cttgttttta tactcaatga
     1861 aaatcaaaga gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg
     1921 tagatggaag ctgacgtggt ttgaagagat tttcgaagag tattaagtcg tataaatcgt
     1981 cgacgctgtc gcaatggtat gccactggtt ggctgtagtt gctgcgaaat ccttgtctgc
     2041 gtagaagtca gtaaatggta ggatttcaac ttccagctcg tcgatgcggt caagctgacc
     2101 agccagataa aactcgatac ggctttctgc tcgtttgatg cgttgcaaga gtccgcccat
     2161 acggatgtca actgtatcca aaccaaagac cttgttttct ttcagccatt ggtgactaaa
     2221 gagggcatgg aagtcttcaa tttggcttct aagttctggt aattcttgtc tggcgatttg
     2281 ttgtaaactt tctttatcat ccgcttggta ggcctgacga atgcgtcgtc ccacatctac
     2341 tttgctactt aaaatagcat tcaactgggc ctgagtttca aagagatagg catagtttcc
     2401 agctttttct ttaatgttag caagcgtctc agcagcctga gcgaagtgcg gtttgtcctg
     2461 ttcaggtgtc atgtgttgat caagaatcgg acaaagaata tcctgataaa aaacatagcg
     2521 gttgggattg ataccgctga gattgcctgg taggtctggt aagaggttgg caaggtcaat
     2581 ctgcataaaa tcctcaaccg ttagaccagt attggtcttg aagtgcgcag acaaaccatc
     2641 taggtcattg cgatagctga gttctgccca gatttgcaag cttggtagga tagagaactg
     2701 ggcagtttca ccaccattgt ctccccaacc cgttacgatg acttctttaa tctgattggc
     2761 acggcaggct ttattagcct cgatagccac tagacggcta aaatggttgt gaggtgtaaa
     2821 gccaatccac ttccaagctc cccctgcaaa tgcaaggtca tggctaatct tgtgatgatt
     2881 gcggaaatta cggttgtatt tttcctcgct atcctgataa taatcccagt aaaccagagt
     2941 cacacggtct ttgagacggt ctaggtagac acgagtttcc tctggaattt ccacatcacg
     3001 atcgtactgg ccatccgctg acatgagttt gaagaacata tcactccaca tctggcagtg
     3061 gaaaccatat ttgtcagcaa tatccagcac gcgctccaag tgttggcaca tgaggagact
     3121 acgatccaca acaccgttca aaatcaggta gcgtcccaaa ccaaccaagt gggcttcgtc
     3181 catcccgata ttgaccttgc gagtcttcag tttagacaac gtggcaaaca tgccatcaat
     3241 caggtcataa accttttctt cgccaatgag aagaatgtcc tctacatcac ggagctcctg
     3301 cacttccttg acaccccatt tgacaaaggc cgacaagtgg gccaaggtct ggatgcatgg
     3361 tacaaaggtc atgtcaaact gttgagcata ggcttctatt tcctgcaact cctctgctga
     3421 ataagctcca cggaaatagc caaagtaagg ctgtccttca atctggtaag tgtcttccat
     3481 gtaaagctca aaggttgagt agcccatgag agccaagacc tcaatcatct gcttggcaga
     3541 agccacattc agcaccgcat ttcgagaaca gtcaaccatg taagccaaat cttcgtaagc
     3601 tgcttgttcc tcaatctcta ctttatcagc ttctgctaga actgttacca acaaggataa
     3661 ggcacgataa agttggtgag gtttgcggta ggtcaattga tagtgacctt cctcaccctc
     3721 gatagagata gaggcttggt cagactgagt gacagccact tccacatctg gtagagaaat
     3781 atgacctttt aaaacctcaa tagcttgcgt ttgtttggga ctaagtcctg taaatcttac
     3841 cattgctttt cctcctgtag ccagttgaca agagcaccgt agagattggc atctgcgtga
     3901 taggtgcagg cctggataac tggtgcgacc gtgtattctt cgtaggtatc gacaaagtta
     3961 tcaacagcct tcttgacatc ttggataaaa tctggatttt gactgataga gccacccaga
     4021 ctgatgacat ctggatcgat gagatactgg atattgagca agccttgcgc cagattgcgg
     4081 ttcatgcgct caatggcttc ttgacaaaga gcattaccag ctgcggcctc ttggtaaatc
     4141 ttgcgaccgt cccaatcagt atgaccagat ttttcaatca cgtatcgtac catattccca
     4201 gttgatgcta gttgcgacca gttattaagt ttttcagcag gggcaagggt tgtcatgtag
     4261 ccaaattctc cacccaagcc gtggcgacct cgatgaagtc taccattgat aatcatggct
     4321 ccgccaatcc ctgtcccaat cacgacacag gctgcatttt caagatctgg atgagctagt
     4381 agttcactga gtccaacgca gttggcatca ttttctaaat ggacaggtag ctgataagag
     4441 ctaagcgcct cataccaaga aaagccatgg atgtagggca ccgcactgaa gccatcaatc
     4501 acacctgtct cttgattgac tgcacctgga acgctcatag caatcccact gtaatcctgt
     4561 tctgacaagc gttgatctag ccacgctagt aaatcctcca agttttcagg cgttgaaata
     4621 cttgtcttat ccagtatttt cccatcagga gtcagactgg caaacttaat cccagtccct
     4681 ccgatatcaa tcgttgcaat ggtcattgtt tttaccataa aaaggggcga atcagcagtt
     4741 agttcttact ttttcgcccc tcctttcttt tgatgtttac tttttgaaat taaatttctt
     4801 cttttttgat gaattctgta cgaatctctt gtggatccaa tggtcctgaa tgaactggat
     4861 atggtcgctc aagtaagtca agaatggttt gttgatgttc tgatatgtgc acattttctt
     4921 gactcatatt atagtaacgg aagacatagc cttcttcatt ttccgccact ttaaaggctg
     4981 ttggacaaac ttgcggtatg ctgagaacag aatggctcaa gaggctacca gtcgcaacca
     5041 cgcttccttc ctgtctagca agctgaaggc tggtaaacgg tgtctgcaag gctttggcac
     5101 gacggaaagc tgaaaagcgt tcttgggctt ggtggcattc aagtgcaaac tcgacttcaa
     5161 actcacgcaa gcattgtgct tctggcgttg ggaagtagcc ccagtcacct agctcacctg
     5221 atgcacgcaa aatggtcacg gcaatggtgt tatccccaag gatttcgtat tcattcaatc
     5281 ccttattgga tacagtcacc cctttttcat cgtcatacag actgacaaaa gcttgttggt
     5341 gttgaggatt ttcaggattt tcccatgaag cagctggttt gtttggtcgt gtcaccacct
     5401 catagatact ttcagaatca ttgcttggac gcgtgttatg agtcttgacc aagagacgga
     5461 tacggtgatc cttggcagtg ttagtaaagc gagtcttgaa gcggatttgt ggattgtcaa
     5521 cgaagacagt caactcagtt tccagaggaa tgtttgtcaa ttcttctgac cgtccagcct
     5581 cacgcttcat aaactcgatg ataccttgtt gctcttcttc tagcttttca tccgcactga
     5641 caggcacggt caattcatgt ttgagcaaga ttttagcata gcgatctgtg ttttccaaga
     5701 cctcgtggcc cttaagctct gcaaagattg gctctgttcc ttttggttgg aaatagatat
     5761 actcgtttcc gatgtcaccc cggtcttcga agcggataaa gtcttcatag gcttcgtgag
     5821 ttgtcttgtc atatactgtg atattgtcat ccacactcac cgttacgaat ggtgtatcaa
     5881 tcactccgtt ttggtaaata ccctcacggt gttcttgttt tccttccagc aattggaagg
     5941 ttgtccaaga aagcggcgct aggtgaactg gaatggtcac gcgcacttgt cgagcaatac
     6001 gagcttggcg gaacttgtct tttggtaaat cgtactcaaa attagctccg aggtcttcga
     6061 ttgtagcctc tacaggacga ccatccaagt cctccacacg gtaacttggt aagataagag
     6121 cagccatctt tttgtagcct tctgttgggt gcaattcctt gaaatcacaa gtcgccacat
     6181 caatcactgt gctgacagta tcgaccttat catgcaagcc tgtgttaatg acagtaaaga
     6241 gatagtcact ttgagcctta tccgtagcaa ttttaccctt ccactcgttg agcaagttac
     6301 ttttaacaaa gtttcctact tggttgacct tggcaaaacg cgtttccatc tcgcggtgaa
     6361 cttcgtccac gctacagcca cagatactat catgtggcgc attctgcaaa agtgttttcc
     6421 aagcataggt caactggtcc ttgtggttgt gtccaccagt gataatagtc aagggttcta
     6481 ccacttgctc taggaggttg ctattttctt ggaaggcttg ttttaggtaa atgcgggatg
     6541 aagaagtgtt ggcaagtgtg taccagccat ctgtttcctg actggtcaac tcgcctgtaa
     6601 cagttgataa gtgttcagga agcgcacctt ctacagcttg aacatattca tcaaaagaac
     6661 tatgaacaaa gattacatcc gggaagagtt catttgccac acgaatggct tcgctcagat
     6721 ttttctgtac aggctggtgg tcacagccgt tcatcatcaa ccattggttg gtcgaagcgt
     6781 aggcacgcac atctgacaat ttttgtttcc agaaggtcaa ggcctcatct ttgtcaactg
     6841 ggatttcatt cccattactg taccagttgg caaagagaat acctaaaaca cgactaccat
     6901 ccacaccctg ccagtacatt tctgaaaact gggatgtaaa ccgctcatct tcaaggactt
     6961 ggttgtcaaa tccaatcggc ttcacaccac gaccaaaggc tgccacgtga atacctgatt
     7021 tttgaaggat ttgaggagct tgtcccatat ttccaaaggt atctggaaag tagccaatct
     7081 gggttgattt accccatttg gcagcttctt gttgaccaat caaggtattg cggacattgg
     7141 cttcactgga gatcaaataa tcatcctgca agatgtaaaa gggaccaatt ttaagcttgc
     7201 cctcgtcaat gtagcgttgg accttgtcac gattttcagg gcgaatttgt aagtagtcgt
     7261 caaggacaat agtttgtcca tccaagtgga aactcttgaa ctcagggtca ttttcaaaga
     7321 gatcaaagag attgtcaaac aattccacca actgcatacg atgactttca aaaggcaagt
     7381 accactcacg gtcccagtga ctatgtgaga taatatgtac aacaacattt tccatgaagt
     7441 aaaacctcat tctaaattta aattttaacg ttttaaatgt aaacttgtga ttctgataag
     7501 aatcggttga gctaaagcga gccccttagc gaatatccaa gtaatccaag accaactcac
     7561 agaacatcat gttagcccag gagaaccatt cacgagagta gagggtcgga tcatctacat
     7621 gaaagctttc gtgcatgaca cctgtaccac catcgcaggc aaccagctga tccagcaaga
     7681 attttttctc tgccttatct cttgttgtca agccttggat agaaagggcg attggccaga
     7741 tatagcgata gaaggtatga gaactgccga gaccgcttgc gtattctcct tggtagaagt
     7801 atggattttc agagctcaaa atggtacgac gagtagcttg atacacttca tcatcgaccg
     7861 aacagtagcc cagatagggc gcagctagta gacttggtac atttggatca tccatgatgc
     7921 tggcatttcc taggccatcc acttcaaaag cgtaaatctt ttcgcccttg ctgttggtgg
     7981 tgtaagcgta gtttttgatt ccttcttgga tttcatcctg aagacgcttg gcatcagcaa
     8041 taacactctg gctatcagct aggtttaatg ctgcgaagat ttcttgcaca taacccaaga
     8101 ctactacagc aaacatattt gacggaatca agtaactata ctggcaacag tcatcactcg
     8161 gacgaaaagc tgaccaagtc atacctgtca ctgcaaagtc aggtccaaag ccatcattta
     8221 ccaaggtgtc ttccttacgg tccgtatctc ggacaaaacg ataaggagag ttcttgtggt
     8281 cttgttccac cgtccacaga tggagaattt ccttagtcgc tgcgacaaaa atctcatcaa
     8341 actgactagt ctcgccagtc tctttccaga ggagataagc caactgcaaa ggatagcaaa
     8401 gcgaatccac ctcatacttg cgctcccaga tccagccgtt aaggtctgtg tggtcagtct
     8461 cgtggtgccc tttccagttc tcctcaatgt tgaaggagtt agcataggga tccttgagta
     8521 ccaaggtcat ctgacgtttg accaaacctg caatggtctg acgcaggagg gcatctcttt
     8581 tagctacatg aaggtagggt ctgagttggg ctgtcgaatc tcgaagccac atggcaggaa
     8641 tatccccagt caagacaaaa gttgaaccat cttctaagat ttcaaccgta ttgtccaagg
     8701 tatcggtgta gcaacgctcg aaaacatcca cccactctgg atagtcctta gcccgctctg
     8761 ctacttcatc tagccactct ctgacgattt ctttcgaata aaccatttta aattttacct
     8821 ctttcaaaca agtttcatgt tcagtatata gcttttgaga cagaaaatac atacacaaat
     8881 gatagtcatt tttctacaaa atagttattt ttgaaactcc ttttctaaag gccctctttt
     8941 tctgatataa tgtagaaaaa cagctaaagg aaagactatg aaaccactac ttgaaaccat
     9001 cgatacccgc tttggaacta ccaacaagca tgccttttct cggggaaata ccctgccata
     9061 cacaggcgtg ccttttggga tgaattactt tgtgccccag accagtgacc aggatggatc
     9121 ttggtttttt gatccacatc tgcctatctt tcaggggatt cgattaactc accagcccag
     9181 tccttggatt ggggactact cttggctcct tctgacacct gtcaccagtc aactgggtgg
     9241 agacagcctc tttcaccgcc aatcttccta tgatagggat aaggcctctt tccaacctca
     9301 ttatctaaag attttctccc tgcgctatca gattgaaacc cagctcacac cgacttgcta
     9361 cggtgcttct attcgtttga agcaaaagca aggcaaagcc ctctccctct atcttcacgc
     9421 aacagatgaa ctgacagtag agcaagtaga taagcgaact cttgccctgc aacaagaagg
     9481 taaaactgaa actaacaaaa attcgctaac gatgttcact gccctgcaaa tgaacacgga
     9541 tattcttgct atcagccaag aagctggaga ctggcgaatt gacttagcaa gtagtcaaac
     9601 cgagatgcaa ctagccactt ctttcatctc tccttctcaa gctctaatca atctacctca
     9661 agaagatttt gatagctgta aaacaagtgc ccaagcggat tgggaaaatc tcctccatcg
     9721 ttttgacatt atagagacag gagaggctga ccgaaccttc tttgaccact gcctctacag
     9781 actcttcctc ttcccacaga ctttttatga ggttgatgag tcagggcaag ccatccacat
     9841 ggatctggct actggtactg tcaagcctgg tgtcctcttt agcaacaatg gtttctggga
     9901 taccttccgc accaccttcc ccctctttgc ccttatcata ccggagcact atcaacgctt
     9961 tttagaaggt ttcctcaata gctaccgcga tactggtttc cttccaaaat ggctggctcc
    10021 agatgaacgg ggtatgatgc caggtacact tttagacggt attatcgcag atagcgcctg
    10081 caaggacatg gcccccgacc tagaaggaga actcttccaa gccatgctca aaacagccag
    10141 caaagccgac cctctcggca tcaatggccg ccacggacta gcccaatacc aagaactaga
    10201 ttacctctct accgaccacc acgaaagtgt tagccatact ctagactatg cctatagtga
    10261 cttttgtatc gccaactgtg ccaaaaaact aaaaaacata gaaatcgctg aaacctacaa
    10321 ggctgcttca caaaattacc gccagctatt tgacgctgag acaggttaca tgcgagcacg
    10381 agacaatcaa ggaaactttc accctgactt ctctccttat agttgggggc gagactacgc
    10441 tgaatgctct gccattcaag ctactttagg cgttctccac gacatccctg gcttaatcca
    10501 actgatgggt ggaaaagaaa cctttagcaa ctatcttttg aaagcctgtc aagatgctcc
    10561 cctctttgaa acaacaggct atggttacga aattcacgaa atgagcgaga tggctactgc
    10621 tccttttgga cagatagcca tttccaacca gcctagtttc cacattcctt atctcttccg
    10681 ctacagcgat taccctgact acactgccct tcttatcaag acgctccgtc agaaagcttt
    10741 tcacccaagt tgggaagcct atcctggaga tgaagacaat ggtagtctct ctgcttggta
    10801 catctggtca gctctcggat tttatccaac ctgtccagga aaaccaagct atgacctcgg
    10861 aatctctctc tttgaccatc tacgagtcta cctcgctaaa gaagataaat ggctggatat
    10921 ccatactaaa caaaaccaca accattttaa ctttgtcaaa gaatgccgac tggacaaaac
    10981 actcgtatca actattcaac accaagacct cttaaaagct gaacaactaa ctttcaccct
    11041 cagctggtta ccaagtcatt aataaccaaa agaacctttg catcgcgcaa aggttcttct
    11101 tttatgaaac ttggacttga agttgatcca caagctgacc atccaccgtt aggttcagat
    11161 agaaatccaa ggttttatct cctgcgaaat acagggttgg tagatgcaaa tcttttttgc
    11221 tttcccctgc ttggaattga agaacttgaa tctcatcctg ataggcgaca ccatggacac
    11281 ctgtccccgg ttgaatcgaa atcttagcct ctaaagagga gctactttca ctacgttcaa
    11341 tcctaaaatg aagagtctct ccctttgcca cagctaggct tttttctgca aatgctagtt
    11401 cctgaacaac ttcttttttt gataatccag gagttttata aagggaaatc ttggtcagta
    11461 gaggcataga ttgtgcttcg gtaatcatca cgcgcacctt ctgtgcctct actagcggac
    11521 ctcgcaagag gcgcttatga ccaactgtga agcccctgcc aaattcctgc cagacaccat
    11581 ccacctctac ttgcacatgg aaagcagaaa tacgttggcc taacttcaaa tcttctctca
    11641 actcaattac atcaaaagtt ttaggagaac ctaagtcgag ttctaactgg atgggcaagt
    11701 ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt caaatggcga caagcaaagt
    11761 ctgcggaaag agctggacca gatacctcag ctcccagagc caaatcttct ttatagagct
    11821 cattgcgata ggtcgcaaat tcataaagtc gttcaatatc ctttgcatca aagagcccag
    11881 cttgattcgg cggaatatta agcaagagtg gagttcctcg ccctactgag tgaaagtaga
    11941 tttcgaccaa ctcctcgaga gacttaggat cctgatcctc atggtagaac cagcctggac
    12001 ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc cgagggatcc ccgtgctgaa
    12061 gatagttcag ctctgcttct gttcctagtt tatcaggatt caccttttgc cacagtggat
    12121 cacctgcata ccctcgttca ttgccaatcc agcggatact ggtgccttct gttgaaaaaa
    12181 tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca tttttcaaat tcataattaa
    12241 ccttttgcgc gccctctcct ctggcaccat ccatccaaac ctcagcgaac ttaccagcat
    12301 tcccatagtt aggatttgat aagatttcct tcaactgagc cagataatag gcattgtagt
    12361 ccgcttctcg gtccacatga tagaggggac tatgggcatc ccacggtgac aggtagaccc
    12421 ccatatccat atcaaactct gtggcagctt gggatacttc aaggagcaag tcgccctttc
    12481 ctctcctcca aggactgacc ttaaccgaat aatctgtgtg agctgtcgga taaaggacaa
    12541 agccatcgtg gtgcttgacc accaaaatca actttttgaa gcccgtttcc ttgagcacac
    12601 gaacccactc acgcgcatcc aactgactcg ggttaaagcg ctcaggatcc tcctgtccag
    12661 tcccccattc ttggtcataa aaggtattag gaccgaagtg gataaaagct gctagttcat
    12721 ctcccagata agctagctga gtctgacttg gtaacggtcc atgcggtttg attttcttca
    12781 tcgttatata tctccttctt tagcaacttc tcttgttcac aaggttatcc acaggttgtg
    12841 gataataaaa aatgatctaa ccgccagctc tttccaactc caactggtag gctcaggatt
    12901 ttgctcctca atgttccctc ttcaaacagc tctgtcatat ggttctgcta acacctctca
    12961 gaatgctact ctccataatt attctcaggc ttctttcagg tcattgtgtg aagaccattc
    13021 actctccaga cttttccaca gattgtgaat aagtgattat tctaaactat catctcgtcg
    13081 actataacaa aaaataaaaa gagggtcaat aagataatta tctcttccta aatactcaga
    13141 aaagattcta taatttgtac aattgagcaa gaaatgcttc tccaaaatct atcttcaaaa
    13201 gaatgttgca tctttttatc ctttcacaca aacatttctc tttatacaga tccaagtgat
    13261 aaccagatga taattggaca ctttttggtt atttgtgtat tttttgaaaa attttttaaa
    13321 aaaattttat atcctcttta atagaagttt atgcatttgt atatatgtat tccatcctat
    13381 gttgtgtata ataacataaa attgtgctaa atatcataat ttatattatt ttccgagaaa
    13441 ttatagccat tgacattacc taggaattgc gttataacat acatgtaagc ggtacccaaa
    13501 atggtgccaa gtcaaaattt ttaaggagga aaatacatgt cttcacatcc aattcaggtc
    13561 ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc gtccaggcaa ggagttagaa
    13621 aacttgttgc cggactatct tgaaaggctt ctttttgatg atattccttt cttggaagat
    13681 gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg atgaaggaat tgaggttctc
    13741 tacctagaac aactcgctgc tgaatcattg acctctccag aaatccgcga tcaatttatc
    13801 gaggaatact tagacgaagc caacatccgt gatcgtcaaa ccaaggttgc tattcgtgaa
    13861 ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa aaacaatggc tgggattcaa
    13921 aaagttgaat tgccagaaat tcctgacgaa gctaaagatc taactgactt agttgaatca
    13981 gattatccat ttgcaattga cccgatgcca aacctctatt tcactcgcga cccatttgca
    14041 acaattggaa acgccgtatc gcttaaccac atgtttgcag acactcgtaa ccgtgaaaca
    14101 ctctacggta agtatatctt caaataccac ccaatctatg gcggaaaagt ggatttggtc
    14161 tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg agctagttct ttctaaagac
    14221 gtccttgcag taggtatttc tcaacgtaca gacgcagctt ctatcgaaaa acttttggtc
    14281 aacatcttca agaaaaatgt tggcttcaag aaagttttgg cctttgaatt tgctaacaac
    14341 cgtaaattca tgcacttgga tactgtcttc actatggtag actatgacaa gttcactatt
    14401 cacccagaaa tcgaaggcga ccttcacgtt tactcagtta cttacgaaaa cgaaaaactt
    14461 aaaatcgttg aagagaaagg tgacttagct gaacttcttg ctcaaaacct tggtgtagaa
    14521 aaagttcatt tgattcgttg cggtggtggc aatatcgtag cagctgcgcg tgaacaatgg
    14581 aacgacggtt ctaacacttt gaccatcgca cctggtgtgg tagttgttta tgaccgcaat
    14641 accgtgacca ataagatttt ggaagaatac gggcttcgct tgattaagat tcgcggaagt
    14701 gaattggttc ggggccgtgg tggacctcgt tgtatgtcta tgccatttga acgtgaagaa
    14761 gtgtaatcgc tgttcggcat tcgtcaatag aaaatgtaaa aaatagaaag aggaaataat
    14821 aaaatgacaa attcagtatt ccaaggacgc agcttcttag cagaaaaaga ctttacccgt
    14881 gcagagttag aataccttat tggtctttca gctcacttga aagatttgaa aaaacgcaat
    14941 attcaacacc actaccttgc tggcaagaat atcgctctcc tatttgaaaa aacatctact
    15001 cgtactcgtg cagcctttac aactgcggct atcgaccttg gtgctcaccc agaatacctc
    15061 ggagcaaatg atattcagtt gggtaaaaaa gaatctactg aagatactgc taaagtattg
    15121 ggacgtatgt ttgacgggat tgaattccgc ggattcagcc aacgtatggt tgaagaattg
    15181 gcagaattct caggcgttcc agtatggaac ggtctaactg acgaatggca cccaactcaa
    15241 atgctcgctg actacttgac tgttcaagaa aacttcggtc gcttggaagg cttgacattg
    15301 gtatactgtg gtgatggacg taacaacgtt gccaacagct tgctcgtaac aggtgctatc
    15361 cttggtgtca atgttcacat cttctcacca aaagaactct tcccagaaaa agaaatcgtt
    15421 gaattggcag aaggatttgc taaagaaagt ggcgcacatg ttctcatcac tgaagatgct
    15481 gatgaagcag ttaaagatgc agatgttctt tacacagacg tttgggtatc aatgggtgaa
    15541 gaagacaaat tcgcagaacg tgtagctctt cttaaacctt accaagtcaa tatggactta
    15601 gttaaaaaag caggcaatga aaacttgatc ttcctacact gcttgccagc attccacgat
    15661 actcacactg tttatggtaa agacgttgct gaaaaatttg gtgtagaaga aatggaagta
    15721 acagacgaag tcttccgcag caagtacgct cgccacttcg atcaagcaga aaaccgtatg
    15781 cacactatca aagctgttat ggctgctaca cttggtaacc tttatattcc taaagtataa
    15841 ttttagataa taaaccgtct accaacagct atgagggctg cgactaatag ctttagtccg
    15901 gtcctctttt atgtaatggt aatctattat ttcttataaa atatgtgaaa aatcattaaa
    15961 ttgaaatcta aacgcattct attgagtgtg ataaaggaga atttatggca aatcgtaaaa
    16021 ttgtagtagc tttgggagga aatgcgattc tttcttctga cccatcagca aaggctcaac
    16081 aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt gattaaaaat ggagatgatc
    16141 tgattatcac tcacggtaat ggacctcaag ttgggaatct cttgctccaa catttggcat
    16201 cagactctga aaagaaccct gccttcccac tcgactcact tgtcgctatg acagaaggta
    16261 gcatcggttt ctggttgaaa aatgctttgc aaaatgctct cttggatgaa ggcatcgaaa
    16321 aaaatgttgc ctctgttgta acgcaagttg tcgtagataa aaatgatcca gcttttgtta
    16381 acttgagtaa accaatcggt cctttctatt cagaagaaga agcaaaagca gaagccgaaa
    16441 aaagcggagc gactttcaag gaagatgctg gccgtggctg gcgtaaggtc gttgcctcac
    16501 caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac tcttttaaat aatggtcaag
    16561 tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa agaaaacaat ggacatttga
    16621 ctggtgtcga agcggttatt gataaagact tcgcttccca acgtttggca gaattggttg
    16681 atgcagacct cttcatcatt ttgacaggtg tagattatgt atttgttaac tacaacaagc
    16741 caaaccagga aaaattggaa catgtgaatg ttgcccagct ggaagaatat atcaaacaag
    16801 atcagtttgc accaggtagc atgcttccaa aagtagaagc agctatcgct tttgtcaatg
    16861 gtcgtccaga aggaaaagca gttattactt cccttgaaaa tctaggcgcc ttgattgaat
    16921 ctgaaagcgg aacaattatt gaaaaaggat aagttgtttt actaataaga tgtattctat
    16981 ttctagtatc tttatatcaa attagaaatt attcttgaaa acatgtacaa tatttcaaaa
    17041 gatactagtt ttagacttta atatggtaaa acaaatataa atagaaagcg ttttcttgaa
    17101 tgtttattta agaaagtagt tggtttttta cactttgtta gacatcagga ggaaaaacaa
    17161 atgagtgaaa aagctaaaaa agggtttaag atgccttcat cttacaccgt attattgata
    17221 atcattgcta ttatggcagt gctaacttgg tttatccctg cgggggcctt tatagaaggt
    17281 atttacgagg ctcagcctca aaatccacaa gggatttggg atgtcctcat ggcaccgatt
    17341 cgggctatgc taggtactca tccagaggaa ggttcgctca ttaaagaaac gagcgcagcg
    17401 attgatgtag ccttcttcat ccttatggtt ggtggtttcc ttggcattgt caacaaaact
    17461 ggtgctcttg acgtagggat tgcctctatc gtgaagaagt ataagggccg cgaaaaaatg
    17521 ttaattttgg tactgatgcc tttgtttgcc ctcggtggta caacttatgg tatgggggaa
    17581 gaaacaatgg ccttctatcc actccttgtg ccagttatga tggccgttgg ttttgatagc
    17641 ctgactggtg ttgcaattat tttgctcggt tctcaaatcg gctgtttggc atctactctg
    17701 aatccatttg cgacaggtat tgcttcagcg actgcgggag ttggtacagg ggacggtatc
    17761 gtacttcgtc tgatcttctg ggttaccttg actgctctta gtacttggtt tgtttaccgt
    17821 tatgcggata agattcaaaa agatccgact aagtcactgg tttatagtac tcgcaaagaa
    17881 gatttgaaac actttaacgt agaagaatct tcatctgtag aatctacact tagcagcaaa
    17941 caaaaatcag ttctcttctt atttgtgttg acattcatct tgatggtatt gagcttcatt
    18001 ccatggacag accttggcgt taccattttt gatgacttta atgcttggtt gactggtctt
    18061 ccagttattg gtaatattgt cggttcatct acttctgcac taggtacttg gtacttccca
    18121 gaaggcgcaa tgctctttgc ctttatgggt atcctgattg gtgttattta tggtcttaaa
    18181 gaagataaga ttatctcttc cttcatgaat ggtgctgctg acttgctcag tgttgccttg
    18241 attgtagcga ttgctcgtgg tattcaagtt atcatgaacg acggtatgat taccgataca
    18301 atcctcaact ggggtaaaga aggcttgagc ggtctatctt cacaagtctt tatcgttgta
    18361 acttatatct tctatctacc tatgtcattc ttgatcccat cttcatctgg tcttgccagc
    18421 gcaactatgg gtatcatggc tccacttgga gaatttgtaa atgtccgtcc tagcttgatt
    18481 atcactgctt accaatctgc ttcaggtgtc ttgaacttga ttgcaccaac atctggtatt
    18541 gtgatgggag ctcttgcact tggacgtatc aacattggta cttggtggaa attcatgggc
    18601 aaactcgtag tcgctattat tgtagtgacc atcgcccttc ttctccttgg aaccttcctt
    18661 ccattcctat aaaatagtga gtgaggtgat tccatgaaaa tagatataac aaatcaagtt
    18721 aaagatgaat ttcttatatc attaaaaacc ttgatttcct atccttcagt actcaatgaa
    18781 ggagaaaatg gaacaccttt tggacaagca atccaagatg tcctagaaaa aactttagag
    18841 atttgtcgag acataggttt cactacctat cttgacccta aaggttatta cggatatgca
    18901 gaaatcggtc agggagcaga gcttctggcc attctctgtc atttggatgt tgttccatca
    18961 ggtgatgaag cagattggca gacaccgcca tttgaagcaa ctatcaaaga cggctgggta
    19021 ttcggacgtg gtgtccaaga tgataaaggc ccttcgctcg cagctctcta tgcagtaaaa
    19081 agcttgctgg accaaggtat tcagttcaaa aagcgcgtac gctttatctt tggtaccgat
    19141 gaggaaaccc tctggcgctg catggcacgc tacaatacca tcgaagaaca ggccagcatg
    19201 ggctttgcac ctgactcatc ttttcctctg acctatgctg aaaaagggct tctacaggtc
    19261 aaacttcatg gccctggatc ggatcaacta gagcttgaag taggaggcgc ctttaacgtt
    19321 gtaccagaca aggccaacta ccaaggtccc ctctatgaac aggtttgtaa cgatctcaaa
    19381 gaagctggtt atgattacca atccactgaa caaaccgtaa cggttctcgg agtgccaaag
    19441 catgctaagg atgctagtca aggtatcaat gctgtcatcc gactagctac cattcttgct
    19501 cctctccaag aacaccctgc tctcagcttt cttgcaacac aagcaggtca agacggcaca
    19561 ggaagacaaa tctttggtga tatagcagat gaaccttctg gtcacctatc ctttaatgtc
    19621 gcaggtctca tgatcaatca tgaacgttct gaaatccgta ttgacattcg gactcctgtc
    19681 ttagctgata aggaagaact agtagagttg cttacaagat gtgcacaaaa ctaccaactc
    19741 cgctacgaag agtttgacta tctagcgcct ctatacgtcg caaaagacag taaactcgtt
    19801 agcacactga tgcaaatcta ccaagaaaag actggcgata acagtcctgc tatttcatcc
    19861 ggtggtgcca cttttgctcg caccatgcca aattgtgtag ccttcggcgc cttattccca
    19921 ggagcgaagc agacagaaca tcaggcaaat gaatgtgccg ttctagaaga tttgtaccgt
    19981 gctatggata tttatgccga agccgtctat cgacttgcaa cttaatcagg caactgtttc
    20041 taccaaaaaa aaatcgaccg attaatgaac tgcaccccaa aagttagaca gaataaatct
    20101 aacttttggg gtgttttatt atgaaattga gttatgaaga taaagttcag atctatgaac
    20161 taagaaagca aggacaaagc ttcaaacagc tttcaaaaag atttggtgtg gatgtttctg
    20221 gtctaaagtc atctgaatct ttgagatgag ctttataaat cgcttttttc agtttttgca
    20281 ctggtgtttc gataaactca aactttttag ccgtggtatt gcctgatttt atagtatatt
    20341 gaaactagaa tagtacacct ctacttctaa aacattttta gaaatcgatt tgactgtcct
    20401 gatcgatttg tcctgttctt atttcatttt actatatttg agccactttg tctttaacgg
    20461 ctttattcat aagctcttgt aatttttctt tactatcaat tacttctgat tttccgttgt
    20521 aatttattgt aataggtttt aacttaccta atttctcgac acgctcatta atttgatctt
    20581 ttttgaaggc tgcatatgtt tttcctaaga ttttttcgaa aatatattta tcagatagcg
    20641 gtttgccttc ttcttcagct tggtttttgt attgatttga aacataagga acaaatcctt
    20701 catagtaacc taatgctccc ataagttcaa aagcttgttt tctaattcaa accattgcaa
    20761 ctcagatttc agcttttcag ataaatcctg ctcatccaaa taatgacttg aaattagtgc
    20821 tgaactcgtt tctgtatcct gtacaggctg atcacccata ccagcaaaaa ataaactcgt
    20881 tcctagcaag accgaacaag ctcctattgc atatttcctc aaagaaaaac gctgctttct
    20941 ctcaaattga aattctttca tcccatctcc catcattcat tattactgta tattttgtat
    21001 atcagaaata gtttgtattc acaaatcttt ctagttattc ccttatcatt cctaattaag
    21061 ggagataaca tacaataatt tttagttaaa tgtatatcga tgttttttgt ttttcttaat
    21121 aaacgcaata caaaaagagc ctgttgccaa gctctttgta ctcaatgaaa atcaaagagc
    21181 aaactaggaa actagccaca ggttgctcaa aacaccgttt tgaggtagta gataagactg
    21241 acgaagtcag ctcaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagtaaca
    21301 tctatacggc aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt attagtctat
    21361 tatttcttct cagcgcgaag ggctgacaag atttgtgttc ggatatcatc cacaccattt
    21421 ggagtatttg gtaaaaagat agtttgattt cctttagagg caaaggtatt caaggtatcc
    21481 aaatactggt tggtcaagag gatagacatg atttgttctt ctgtcatgcc aacattggct
    21541 tccttgagtt cggtgataga ctctgccaat ccatccacaa tcgccttacg ttgttgggca
    21601 atccccacac catgaaggcg gtctttttct gcttctgctt cagctgcagt gacaatttta
    21661 atcttgtcag cttccgccaa ttcttgtgct gcgacccgct tacgttgcgc cgcattgatt
    21721 tcattcatgg attgcttaac ttctgcatct ggttcgacct tggtaatcaa ggttttcacg
    21781 ataatgtagc cgtaagtggt catttcttct gctacttggt gttgaacctc aagggcaatc
    21841 tcatcttttt tctcaaacaa ttcatccaag gttaattttg gaacagaaga gcgaagagca
    21901 tcttcgatat aagatttaat ctgagattct ggacgtatga gtttatagta agcatctgtc
    21961 acgctctgct cgttgacacg gtactgagtc gctacattca tcataacgaa cacattgtcc
    22021 ttggtcttag tctcaaccac aatatcactt tgcaacaagc gcaactgaat ccgtgctgca
    22081 atcgagtcaa tcccaaaagg caagcgaata tgaataccgc tattagcaac cttttggtat
    22141 ttcccaaagc gttcaataat cgccaccgac tgctgacgaa ccacataaac tgtactcagt
    22201 gtgactatca ccaataggag cacacaaaca atcagaaaaa tcatgaaaaa tattgccata
    22261 atggaacctc cacaagtatt tttctagtat tatagcacat ttaaagaagg ctgtgccgtt
    22321 tttactgcga tttttcctga aatgtcaata attagaggtg aattgtccta ttgtcgtcca
    22381 atctcttgct aaaataactc tttataaaag gcaatcgttt cttctaaggt tggcataaat
    22441 ggatttcctg gtgcgcaggc atcaatcaag gcattcttag aaaggtattc aaagtcgaaa
    22501 tctttttctt caataccaag ttcagtcagt ttcttaggaa tacctactgt ctcagaaagc
    22561 ttctcaatct caacaatcgc ataatcggca cattcttgat ctgatttacc ttctacatga
    22621 agtcccaagg ctttggcaac attgcggaaa gcttctggta cacgtttagc attttcacgt
    22681 tctataactg gtagcaacat ggcacagcaa acaccatgtg gcaaattata tactgcaccg
    22741 agttggtgag ccattgagtg aacataacca agaccagcat tattaaagct cataccacca
    22801 aggaagatgg cattgaccat accttcacgc gcttcaatat catgtccatt ttctacagca
    22861 cgaggaagat attccttgat aagctcaata gcaccaatag acagtttctt ggttacatca
    22921 taagcaccag gtgttaccaa agcttcaaca gcgtgagtca gagcatccat accagtagca
    22981 gcagtcaggc ctttaggttt ggaaagcatg agttccgggt cattaacaga gataagagca
    23041 aggctattct tgtcaaccat taccatctta accttgcgtt cttcatcagt aatcacatag
    23101 ttaatggtaa tttctgctga tgtacctgcc gttgtattga tagccacaac tggcaagcct
    23161 tttttagcag acttatgaag cccttcataa tcctgtggtt ttccaccatt tgtagccatg
    23221 atagaaatac aactagctgc atcctgtgga gaacccccac caagactgat gataaaatca
    23281 cagccatgtt cttgcaaagc agctacccca tctgtgacat tcttacaagt agggtttggc
    23341 tctacatcgc taaagatgac atattcgatt ccttctgtat ccagtggttt taaagtctta
    23401 ggtaaaatat cactgccttc gatgtactta tctgtaacca aaagtgcctt tttatagcca
    23461 agttccttga tataaggacc cacttcattt acaacacctt ttccaataag gttgactgcc
    23521 ggaacataaa atgtagccat ataattttcc tcctgcgcct ccgcgctatc tatttaacat
    23581 cattatatta ctttttgtat tcgtttttaa ttatttgtga attgtttaac aaatcttttt
    23641 aaaaggatag gagggacgta agttcacctc ctatataaac aagttttatt tatgtagtgg
    23701 tcccaacaac tgacatgcac gatagtctgc tgattctaga tcttctgttc caaataagga
    23761 ccaattttta ggtctaaaga tatcttcctc aggtacatta tgcatattga caggaattct
    23821 caacatagaa gccaaggtaa tcaagtctgc tccaatgtgt ccatatgtta tggctccgtg
    23881 attagctccc caattattca tgacgtcata gacagacttg aaagcacctt ttcctgtcaa
    23941 acgtggagca aaccaagtag ttggccatcc tggatctgta cgattatcta aagtatggtg
    24001 aacatcttca ggaagttcaa gtgtataacc ttctgcaatt tgtagcactg gaccaacccc
    24061 ttttagaaga ttgagacgta ccattgttac tggcatatcc cccttcgtca agaaacgagt
    24121 tgagaatcct cctccacgga agtattcgcg gtttgctggt gggaagtctg tattttcaag
    24181 catagcctgc acttcacttt catccaactc ccagaatggt ttcataacag gtttgccatc
    24241 tcgagtagct tgccctgtac catccaatgt acaagaacca gagttgatta gatgtaagaa
    24301 gccagctgca gcacgaccct ctaaagtatg tcccgttaca cgtttaacag cctctggact
    24361 ccaataagtg cgcacatcag caaagatttg tggagtattt gttaatagat aattaaagag
    24421 catagacaca ccatttagtg aatcattctc tgtcgcaaat acaaatggtt ttcgaatacc
    24481 attccagtca aactgagtat tgaggaaagt ttccataaag tccccatttg ggaaatggtc
    24541 tgtccactgg cgttgacctt ggaaaccagc tactaaagca tggtgaccaa ctgcttcttc
    24601 ctcaaaacca agttcagcaa gtcttgggtt accaaccatt aagtcacgtc caatcatgaa
    24661 catcttaata acaaattccc attgtttttc tttctcttct ttagaaagaa tcaaatcctc
    24721 acgatttcgg tcaactcctt ctttgatatg ttcttttacc caaaccatag cacgttcaaa
    24781 ctcttctggg tcgtaaatac cacggtccat acggcgcgtg aactccgtca tatctaccga
    24841 ttcatttcgc attcctaagt attcttggaa gaaatctgga tttacaatag aaccgccaat
    24901 ccccatcgaa acactaccca ttgataggta agcagtgtct ctcatcaagc cagttgcaag
    24961 agctgcacgc gcataacgta aaagtttttc tttgacatct tctggaatag ctgtatcatt
    25021 agcttcctga acatctctac cataaatccc aaaggctgga atcccttttt gagcatgtga
    25081 agctagtaca gctgcaagat agacagctcc tggacgttct gtcccattaa atccccaaat
    25141 agcatgagga atatctggag acatatccat agtttcacta ccataacacc agcatggtgt
    25201 aactgtaatt gttgcgcaaa catttgattt tttaaacaac tcatgggaag ctgcagcctc
    25261 tggaacacga ccaatagtag atggagaaat cacgcattcc acaggttccc catctggata
    25321 tttcaatgtg cttgaaatca aatctgccac acttttagcc atgttcattg tttgcacttc
    25381 aagtgattcg cgtacacctt gacgacgacc atcaatagtc ggacgaatac caatacgtgg
    25441 atgttgaatc atactatttt cctcttattt ttctgtttct ttcatactac catcgccatt
    25501 atatttacgg tagcctgggt gacgacctgt aaccttataa ttttctcgca ttgagaatag
    25561 acgttctaaa gtcggacgag caatttcttg ctcctcaatg ccctttgtag aaagtaacat
    25621 tcttccgtgg aaggttgtct ttgcgactaa ttctaaagtt tccatacggt agtatgctgt
    25681 aattacatcg cttccgacag tcagagctcc atgattttct aatagcatga catcatgatc
    25741 gggcagataa ggtgtaattg cttctggcac ttccattgta gacggaactc caaatggcgt
    25801 tataggaatt gcccctacca caatcgcgct ctcaattagt gaataagtat ctaaaggaat
    25861 gtgtgcaaga gcaaatcctg ttgcaatcgg tggatgcgcg tgaacaactg aacggacatc
    25921 ctcacgttct tcgtagcacc gaatgtgcat tttaatttca ctagaaggac agtaatcacc
    25981 ttctgcttct aaaatctctc ctttaagatt taacttcacc agcttttctg gtgtaataaa
    26041 acttttgctg ataccagtag gtgttgcaag aatggtatcc tcatctaatc gaacagatac
    26101 attcccatcg ttagcagcaa cccaaccaag ttgccacatc ttatgacaaa catcacaaat
    26161 ctgttcacga attaattttt catcttgaga cataaactca ctcctttcta aaaatgaagt
    26221 tcgaattcaa gatttccgtt actgttaatg gtaatagtaa ccatatgatt tttctgatca
    26281 aaattgagag atggctgatc ataggaatta tttgttcctg ataatgaatg aatagtagga
    26341 agtttatcta tacctcttaa tactatcttt gtaacccttt tctctccaaa ctgagtatct
    26401 ttgatataat gttcttcaat ccacttaatc gcacctttct tggtcaattg tggtagtttc
    26461 tttgcctgat ttgcatcttg agcattagac catagtgaat ctttatttgt tctaaaatta
    26521 tttaaattca ctttcaatcc attacttatt ctctcaaaaa taccataggt atgaggttca
    26581 aattcaacat ccatttctaa agaattaaat tttaatttcc cagtctgttt aacattctca
    26641 tttaccttgt aattatagac aaaccatcta ttatctaatt tctgagcaaa gatatctcct
    26701 tcataattca taggatacag cttatttaag tattcttttc tagcctgagt agagctaaat
    26761 tctggagaag tgatttcctt aatctgaata cggctaccag aaacagactc tttcaattta
    26821 tctgttttta aaacacctgg aatagctgga ataacattat aacgaccagt catgtataat
    26881 ggagtttgtt ctctatcagt atttacgttt acaaagaact taccatttcc tttatttgaa
    26941 tagtctccat gtatgaatac ttttgtatcc tcaagtacct tttctttgga tggtgctgga
    27001 tgcgctatta catatctaaa aaattctttt attacttcgc taaagagtaa gctttcttta
    27061 ttatttacac cataggtata agctgggtgt tcaaaattat aaactacacc tccattaagg
    27121 taaaccccta aagcttcttc tcctagcata gactctggtt cagtcaacca ttgtctatct
    27181 ccttgacttt ttccgatatt accacttgca aacagtttcc atttacctgt ctcataccac
    27241 ttccaagtat ccatcaaacc accccattga taagtatgat ttgaaagcca aagtcccttc
    27301 atataacttt ctgtagttga atcatttccc tcagcagcag gtgtattttt gaacatgaaa
    27361 ataaggttct tccagtactt atcaacagat ttctgaaatg ctatcttacc gttttttcca
    27421 aatgcttttt ctattgcaga accattattt tgttcagccc atataaaata tcctccattt
    27481 ttagctgata cttttaagta atctgccgcc ttattttcaa tatcatttgc ccaaatccaa
    27541 taattctctg tactgaaaat accatgcaaa tttggatatt tttgatacat tttatcaatc
    27601 cagctggtac ttaaccaatg tgccgaagta taataaggca tattaccagc agtgtaaacc
    27661 gtcagaataa ctggaattgg ttcatttttt ccagtcttag gatttacata tttcgctgct
    27721 tcttctaaca tatgttcata aaaatctcta gcagctccat ctcttttagt aagatcatct
    27781 ggatgtaact gtataacagt atatggtttt aagtcatctg gtatattctc ccacttacct
    27841 gttaatgtat ctcctcccca aaaagtatat ttcccttggt taaactcttc tccgttagca
    27901 tataaaggca tcataagtaa cggatgttca ttattaattt cacgacgttt atcaacttct
    27961 gaccaatcat taggattctt aaatttacca tttgccataa acaaggctcc acctaaaacc
    28021 aattcgtcag cccatgtatg tttccctgaa tatgatttaa gttctattgt ctgtgtatct
    28081 ttgggaattt caacatcaac cagaaatgcc gatgtatcat acttaattcc ttttggatat
    28141 tttgaatctg atgagtaaat gactttacca tccgcaacaa cttcaaattt ttgaatatct
    28201 gcgtaatctg aatttaaatg attggcgctc ctatcaattc cgacatagga aataaatctt
    28261 gtaacattag cacccgaaac atcatatttt atactagacg ggttgcttgc tacagttccc
    28321 aatcccttat taaattcgac ttccttaccg tcaattagta attttatttt attattagac
    28381 ccgttattac caggtgtaaa cggtttatct ttctgaactg tttttgattt atcgtcatca
    28441 ccatgagtag catcaaccca ttctaaatca gaaagatata ctcctccatt aattccttta
    28501 ttaagaagat ctggagttat agtttgagta ctaacagttt taataagttt agcatcagca
    28561 aatacaacct catcacccca tgtatgttct cctgcgaatg attttaagga tattttttta
    28621 gcgttttgtg gaattgtcac actaataaat tgtgcctggg tattatatct gaatccttct
    28681 ggattagtta cactactaga atagacaacc tttccatcaa tttctatttc tattctatcc
    28741 actactgcat ggtctgatct agaactatta gcactttgat caattcctat ataagtttca
    28801 aatttttcaa acccttgacc gctgatatca tagctgatta ctgatggaga atctgcgact
    28861 gttcctattc ctttatcaaa atatttaact ttatcatcag aagtgagcaa tgaaatctta
    28921 gtatgctctc ctttatttcc tgttgtaaat ggagcatctt tttgtactgt ttttgtttta
    28981 tctatatcac catgagttgc agaagaccaa tccatatctg aaagatatgt catctcttta
    29041 tcaatttctt tatctttagt aataagtttt tctaagttat tccctgttac tctagcagtt
    29101 tcagtactag ctctgttatt agaattactt tgaactacat ctgcataaac caaattactt
    29161 cctaaaaaac ttgttaaaac agccgtagct attaaaatct gttttgctat ttttttactt
    29221 tccattttta tttcctcaat atttacatac aacttcttca ataacaaata attttgtaag
    29281 atattctgga acacaaagtg ctaaattact taaactgact tttattccag cattcattaa
    29341 ttcatctcca taaaagaact catcaaatct agagacggaa tagcatttat ctttatctaa
    29401 accactaaaa taaactcttg tataacctgg attcaactta ctattcaatt gagcatacaa
    29461 taaaatcgat tggcatttat cttttgaaac aacttgccaa ctagcagaat cacaactaaa
    29521 aggactgttt atcctataga aatccccata ttgaaacaat gaacgatatt ttttataaaa
    29581 ctgaatttgt tctctcactt gttctttttc ttctaccgac aatctcgtaa catctaattc
    29641 ataaccgaaa gaactaaaat aagctacatt tgtcctagtg tccaaactcg tttgtcttcc
    29701 actttgttca tttggagaaa tagaaacatg ggctgtcatc attgatggag aatatccata
    29761 agaagttcca tgctgaattt tcaatctttc tatcgggtcc gtatcatcac tcgtccacgc
    29821 ttgcggtgca taatacataa gtcctaaatc aaaacgtcca ccacctgaag aacaagattc
    29881 aaatagaact gaagggaact tagttattaa acgatctaat aactgataaa gacctaagat
    29941 atatcgatga ccaaattcca tctgctgttc agaatcaagt tcaatactat aaatatctgt
    30001 tatatgacga ttcatatccc atttgatata atccagattt gttttgatta tgattttaga
    30061 aatagaatca aaaaggtaat caacaacttc ctgtctcgtc aaatccaaca catattgatt
    30121 tcttcctact gacttctctc tgtctaacaa atggatagtc caatcggcat gattcttgta
    30181 caaatcacta tcaatagaaa tcatttcagg ctcaaaccac aaaccaaatt gtaaacctat
    30241 tttgtgaatt tcatctgcaa gaaatccaat accttcagga aggcgacttc tatctgttac
    30301 ccaatcaccc agagaacttt tgtcatcttt cctatgacca aaccaaccat catccagtac
    30361 aaataattct atccctaaat ctttagcagc ctttgctaaa tctaaaattt tttctgtact
    30421 caagtcaaaa taaaatgttt cccaactatt gagtattata ggacgactag cttgagaaaa
    30481 attaggatta actaaatgat gtcgataaaa atctgatagt tgttggctca tctgattcat
    30541 cccttgatca gaatagatca caattgcttc tggtgtcaca aaactttcgg caggatttaa
    30601 taaaaaacga aattctactg gatttattcc taccgttact ctagcggtgt caaaatggtc
    30661 aacttcaatc atattttgaa aatttccaga atagataaag ttaaaaccat aaacctcacc
    30721 actatgctct gtagtttccc tccttgatag cataaagaaa ggattttgct gaggacttga
    30781 tgagtatctc aagctatcta ttgcttgaat acctggtcta agcgaagttc tatataactg
    30841 acgttccctc agccatgctc cagaaaattg aataaagtca tattgactat caggtagatc
    30901 tagctgtaag ctcattgctt tcaaaagagt caacttatta ttgctattat ttaaaaattc
    30961 cgtatttcta actaagacat tgtattccgg aaaaattgtg taatttagtc taacagttaa
    31021 atctaatatg gaatctgtta aaataatcgt taatgtttcc acacactgac caatatcatc
    31081 aaatgttgaa ggtagagagt taagacgatt tttccctttt tcaagttcaa aaccttgata
    31141 ttttagtgtc gttatcctac taccattcat tccttgaact tgaaaggctg gatgccgaaa
    31201 atctcctttc ccatatgaag aatattcatt ttgtatcata gactgttgaa tatcctcaaa
    31261 ttcttcagaa aaagatactt caaatcctct tttttcataa gccatcaatt ggttataatt
    31321 ttccttgaca tgaatccttt tcccaaaatg tagatgttga agttccccat tttctaaaat
    31381 tctaaaaata taactactat ctttcattgc caaatgaaaa acggtctcgt ccttattaat
    31441 ataaatcgtc atctctacct cacaattttt tctttacttc ttcagtatca cgatagagta
    31501 cggtgccaat tctatctcat cttcttgaat agtaaaatct ccaattactc tggtaaaatt
    31561 ctctatcgaa agattctcta tttttatttt ttgtttaatc tgagcaggat ttctcagaga
    31621 gagaatttca gtagaagtct tctgattgtg acacttataa ccataaattt caaatttttc
    31681 aggacttcct cctatttttt tactatattt tagtgtttga taattctcct ctatccattt
    31741 gacggcacga gcattggctt tccagcgttc ttcatcaaac atatcaaaag aatagtgaaa
    31801 ctcccaaaaa gcattccctc ttgttgaaat aaataataga taagcttcaa aatctggtat
    31861 tgatgcaaac atttgatgat ccatgtacca ggtatttgca ctgacagcat agattggttc
    31921 atgattataa atcgaccaca taggtaactg tatctcacgt ttttccaaaa attcttgata
    31981 ctgaatatct cggtaagtaa tcatacgatt gatatcatta cctgcattct ctgtaaagcc
    32041 tacatcttga gatatttgaa tccataaact attgacccac tgtaaaaacc atggactagg
    32101 atttacataa gaagtcaagt ttaaccaaca atcttttcct cctctctcct ttcttagatc
    32161 tatcaacagt tgaattaaga actcataaac cgctgtcatg gtatacatac cgtgcggtcc
    32221 actcttatca ggtttgtcag gttgaagtaa ccaaccatca attttccaat agctgatatc
    32281 gaattctttt tgatattcca acatcttttt cttcatttga ttgagatagt taaaatcagc
    32341 cacgtttaca tcatttgaaa tcaaattttt agatccaata tttaactctg gatgtgcttc
    32401 taaccaatca ctcataatga tttctgtccc attgtaacca cctcggggac caatccacaa
    32461 tcctaggctt gaaccaaatc catttacaag atatttaata tttctcaaac catttgggaa
    32521 tttatgattg aattcccaaa ctgattgata gtttgtccaa ccatcatcaa caacataagc
    32581 atctaaatga actccatgat tttcaaatcc atctcgaatc tcagaaaaac tttttaaaat
    32641 accttcctct gtaatatcgg tcatatggtc ataccaggaa ttatactgtt tacggaaata
    32701 actaggttga gctattcctt caacatattc aaaaaatgcc tcttgaatct cttctttttt
    32761 ataagaacat gctcccccaa taatacaaga ccacaaactc ttttcttgat ttacaacagt
    32821 tcccaagtaa tatcttgata catagtgtct accatctacc ttgttttcag acattggaaa
    32881 ttccattcct aagaataaag aattcgcata aacaggttgt cccaattcta cataataacc
    32941 ggaaaaattc gccatttcct taatacaatc ttgtcttttc ggatagaaaa tattgtcttc
    33001 tgtttcaaac tcaaaactct ctacctctac agatttaata acctcagtag atgattctaa
    33061 aactaattgc ttcgaaagaa catcatccct cgattcaaag attaaacgta aacgaatgga
    33121 aggacaaaca aaagaaacct gaattcgcgt atctccctct tccctaacga ttgctgaaaa
    33181 atgatttgaa gaaagtctta taccattctc caatgtaatg gtaaattctt ctttcgaaac
    33241 atttttatca ttactcctgc ccgtttgttt acgatatcag tagtataaaa tcgaccatct
    33301 ccccaaaaga aattacgtct tacattttta ttttcaattt tcatataaac tactctctca
    33361 actcaatttt gattacgcta tcaatcaagt ctggtaatgg ataggtaaaa tgtggaactt
    33421 ctccaaactg tgcaaaacaa attcctttgt aggcattggt cgtccagctt tctgaaattt
    33481 tcacctcact tccatcatga agaaagctca ttctttttac gttttcttta ctaataccaa
    33541 gaagagctaa aggacctata ggttgttcaa atacatgagc ataaaccgta tttccattac
    33601 gagtatagta tccccaatct ggttttggta aattttcatc tccactacat ccataaattg
    33661 cctcaccatt tcgagacatc catcgatgaa aattatctaa tattttctta cttgaatcat
    33721 taattcttcc caaagcatct gggcctacat taagaatcat atttccgttt ttactaacac
    33781 attccactaa ctttcttatc aaagtttgac tagacttata tagataatct gtaggattat
    33841 aagcccaatt gttattcata gttagacaaa gttcccaagg aacaggttca cctttaaagt
    33901 ttcgaatacc ttcgtgagga acaatttgct ctggactaac aaaatctcca gcgtaagagg
    33961 taatttcatc tgtaacgata cttccgaatc cttcacctga tgtttctaat ctattatcta
    34021 cgataacgtt tggctgataa tgacgaacca tgtctattaa ttttgaagct ccccattttt
    34081 cacccaccat gtcttcataa gaataatcaa accataatat gtcaatctga ccataaccag
    34141 ttacaatttc tttaacttga ttgtgcaaat actccaaata acggtcaaag ttaattttct
    34201 catctcgata ggcttcattt cctctcattg gatgatttag atcagcatat ttagggaaat
    34261 caggatggtg ccagtcaatc aaactaaaat ataagcctac ttttaaacct tcagctcgaa
    34321 cagcatctac aaattcttta actaaatctc tacctgcagg tgtatttgtt gctttataat
    34381 ctgtaaattt tgaatcaaac aaacaaaacc catcatgatg tttagccgtt aaaaccatat
    34441 acttcatccc tgcagctttt gcttgtttag cccattctct agggttatat tccttaggat
    34501 caaaagctcg aaaatatggt tcataatctt caatagataa tttctgatga ctacgaatcc
    34561 attccccttt tcctggaata gaatataacc cccaatgaat gaacatccca aatcttgctt
    34621 ctctaaacca ctgagttcta ctattgatag tttcaagtgt atgtttcatc cttttactgc
    34681 tcctcctcct aaagcttcaa tgaagtattt acttgtaaat gcgaatagaa tgattggtgg
    34741 taatacgatt acaacaatag ctgaaaatag accattataa ttagtattaa aacttgtagt
    34801 aaattgacct agtaatgctg gtactgttaa ttcattttta tcaatcacca acatagatgc
    34861 ccaataatat tcattccagt tattaataaa ggcaagtact gctgctgtta aaattcctgg
    34921 tctagcaatt ggcaacatca ctttccaaaa agtttgagca tatgtcgcac catcaatctc
    34981 tgctgcctcc tccaattctt ttggaataat ttcaaaatag ttctttataa taaagaaact
    35041 catagcaatt ccactacaag agtagaccag aattagagca actggggtat tataaatccc
    35101 caactcattt actaatctat aaactggaaa agtcatagct gttgctggaa taaatagagt
    35161 agaatacagc atagaagtca ccaacttctt ccctctaaat tccatcctag caataacata
    35221 tgaagacatg gagatcataa caatgctaat aataactgat atagacacta ctttaaagct
    35281 attccaaaag taagtaaaaa catgaagttt tgtaaaaaca tttatataac cttcaagagt
    35341 aaagtcaatc ggtaaactaa tacctggatt tttcatagga tctgctttta atgatgataa
    35401 aaaaatccac gcaataggga aaatagaaat taaaatggta aggagcatat aaccatatat
    35461 aagaactttg ccttttttac taataccatt tatatgtgta ttcataatca tttcccacct
    35521 ttcagtcttt ttctttctct gaataaaata ttaatacaaa cgataatcaa cattccacct
    35581 aagatttgta taactccaat tgtatttgca cgagcatatt gagttcgtga gctagccact
    35641 gctaattctc gaataacaaa actgatactt tttgttcctg cagcaccatt tgtcaaaaag
    35701 aatacttcgt tatagagcaa aaatcctgaa gttgctgcca taattgaaac agttttaatt
    35761 gtccccttaa tcatcggaat cgtaatatac cactctttcc tccaaccagt aatattgtct
    35821 aaaatagcag cttcttgaac ttcttctgga atagcaaaaa tttgcccaag aatcataatg
    35881 gttgatgctc ctgcaaagaa gatataagcg ccagtcatag ctactatatt taatcctgga
    35941 gtcaacagta ctgaatcttt aaacgatgga ttaaatagat gaataatttg gttaacaaca
    36001 ccatagtttg gattatagat ttgaagaaaa atcaagccca tagcagcact agaaatgata
    36061 cttggtacaa tataaagatt cctagatatc ttccagcctt ttaatttctt agataatgta
    36121 attgcaacag atacagctaa aggaacttga ataataacac caattacagc ccaacgaaca
    36181 gaattaatta gagcttctgt aaaaaatggg tattctttaa aaacatacct ataattttca
    36241 aataatttat caaatccaag aaactcaggg gtgtttaaat ttgtataatc ccatttagca
    36301 aatgaagtta aaaagattgt tactacagaa taaaaataaa atagaaagaa acaaatcaac
    36361 gttggcaaaa gaaataaaaa gataaatcgt cttttttgat tcttcctatt ttgtaggctc
    36421 ataatttttt gtgccataaa caaactcctt ttttcaacta tataagtaaa atcaaggtct
    36481 tatcaaaaga aagcacggat acgtgaccct gtcctctatg aacacaattg aactttctca
    36541 tcaaatacgg gaaggagaaa gtactaggca aaaaagacta atcgctagtc tcgctaaaga
    36601 ctttattcgg tctggtatgt gtatctatct ggattccagt actactgtct acgaactctg
    36661 tccctatctt tctgaacttg ataatttgat tatttttaca aatggtttac atactgcaca
    36721 aaccctatct gaaactgtta aagatagctc caaaatcttt atcacatctg gcgaggtcaa
    36781 acatcaatcc tgttccgtgg tcaactatga taaggaaaat tctttattag atcattttaa
    36841 tatcgattta gcattttgtt cagcaagagg tattgatgac caatatgttt atgaagcttc
    36901 tctcagccaa gctatttcaa aaaagaatat tattgacaaa gcccatgaaa ccatcttact
    36961 gattgatagt tctaaatttt acaagactgg attttttaaa attaatcccc tctccaaata
    37021 cacaaccttt atttctgaca ccgtgccaga ccaaaaatta ttagacgcag tcgaattatt
    37081 tgatggagaa tgggtttctg atattcaatg aaaatcaaat aggaagctag tctcagcttg
    37141 ctcacagtac agatttgaaa actgatcaag tcaagtcccc catggacacg gcaagacgaa
    37201 gctgacatga tgtgaagaga ttttcgaaga gtattcgttc tgtctgctga ctgatttaca
    37261 aatattcacc acatgacatt attttcttag caattctaaa aacagaggct ggacaaaaac
    37321 tcaatttcag gagaaaatgg agtaaacctt cccacaataa aacgcatagt atcaagtttt
    37381 tgcacacctg atattatgcg tttttctgat tttaaagact ttgtcgccta gaccctatat
    37441 ttcaagaatt aagtgacctt gatgatctaa atatattgtg gtatactatt tttgtcatcg
    37501 gttaccgatt acgttcctat gggtttgtga gaggaggtga aactaatgag ccttatcata
    37561 gagctcgctc ttactattat agcggatgtt atagctggaa ttatcttgta tttcgtctgc
    37621 agatggctag atagtaagga gtagaccgac tgactagcct ataaacaccc gttaaatcgc
    37681 taagatacgt caaaaaagcc cttaactacg gccatagtta ggggctttgg tgttctaatg
    37741 aaccttatca attaactaca ttttagcata taatctacaa tagttcaagc attaagtgag
    37801 gttaatgatc taaatttagt gtgatataat acttttgtca tcggttaccg attacgttcc
    37861 tatgggttcg tgagaggagg tgaaactaat gagccttata ccagagcttg ctcttactat
    37921 tatagcagat gttatagctg gaattatctt gtatttcgtc tgcaaatggc tagatggtaa
    37981 gaagtagacc gaatgactag cctataaaca cccgttaaat cgctaagata cgtcaaaaaa
    38041 gcccttaact atggcactag ttaggggctt tggtgttcta acgaacctta tacactaact
    38101 acattctagc atataagccc agatatttca agagttttat ttattttttc aggttccctt
    38161 agttctgaaa ggtctataat gaagttagcc atctagtatc aaaaaaccga ctagctctta
    38221 tgaactagtc gatttctcat caatgcgcca acatttcttg ggcgatttct tggccagata
    38281 ggttatctgg gtagtaggtt ggccagttgt ccatttcttc aaagagggct tcttggcttg
    38341 tgcctccaaa gaagatatgg aaatgttctg ccttaactgg ggcaacattg tggtcactaa
    38401 actgaacata cttgaattgt ccagcgtcag catctgtggc ttcaaagagg aaacgcacgc
    38461 cacgattgcc tttcttgtaa gtcaaaattt tcttaccgac atacttgtaa gtgtatttct
    38521 tgctttgtcc accttgaaca aattccatag tattatcagt aatgttaatc ttagtcacat
    38581 ctgtctgata gccttttgta tagtaagcct tgtactcagc ctgggtcatc ttaccagtta
    38641 acttagcctt gtagtcaaag acttggtcaa acgtgccgtc ttcaaggaaa ggataaactg
    38701 attgccagtt acctgcatag tcactcaagg tacggtcctt gacagctgca tcctcgaagt
    38761 aaccattttg gactgtcttg gtatcctctg ccttttcagg ttcgattgct gggccttctt
    38821 ggtctgttgt ttgtttcaaa gccttgaggt ttttctccat cacggaaatg tagttttctc
    38881 cagccttggt gtcctcttct gtcagacttt ctaaaggatt gaggacatca gttttgacac
    38941 ctgcttcttt tgaaagtgtg ttagcaaggg cttgtgaggc attttcttca aaatagatat
    39001 aggcgatttt atttttcttg acatactctg tcaattctgc caagcgagca gctgatggct
    39061 ctgcatctgg agaaagtcct gagattgcga cttgtttgag tccatagtcc aaggcaagat
    39121 agttaaaggc tgcgtgttga gtcacaaagc tcttttgttt tgcttgagac aagccttctg
    39181 cgtaagcctt atccaaggct tgcaattttt cgatataggc agctgcattc ttctcaaagg
    39241 tctctttttt atcaggataa tctgctgaca agctgtcgcg gatgtgctct actagtttaa
    39301 tggcacgaac tggtgataac caaacatggg ggtcaaactc atggtgatga ccttcttctc
    39361 catggtcatg atctccctct tcttcctcgc cacctggcaa gagcaacata tcgcctgtcg
    39421 ccttgatggt tttcactttt ttcttatcca aggtatctag caatttaggt acccatgttt
    39481 ccatgttttc attttcataa acaaaggtat ctgcatcttg gattttggca actgccttgg
    39541 cagatggttc gtattcatga ggttctgtcc cagcaccgat taggagttct acattagccg
    39601 tatctcctgc gacttgcttg gtaaattcat agacagggta aaaggttgtc acgatattga
    39661 gtttaccatc tgcctgtttt tgattggaac aagccactaa aaacaaggca catagactgg
    39721 ctagtaataa gctaattttt ttcacgttcg tctcctattt gataaaacgt cttactaaac
    39781 tgattagtat aaagacagtt acaaaaataa tggtaatact tgcacttgca ggtgtttctg
    39841 catagtagga aatgtaaagt cctgctacca ttcccaaaaa gccaatcgca ctggcaagca
    39901 gcataaccga tttaaagttt ttccccagac gcagggcaat actagctggc aagaccataa
    39961 tggtcgatac cagaagagct cctgctgcag gaatcataag ggcaatagcc acccctgtca
    40021 ccatgttaaa aagaatggac atggtacgaa ctggcaagcc atccacaaag gccgtatctt
    40081 cgtcaaaagt taagatatac ataggacgaa gaaagagaaa ggtcaaaatc aaaacaaccg
    40141 ccgcaatgac aaagagggaa atgacctgtt cttcactgat agtcacgatc gaaccaaaga
    40201 gatattggtc caaactcatt gaactcgagc ttttaccctt gctcatgaca atcagagaaa
    40261 cagccagacc tgttgacatg aggatagctg tcccgatttc cataaagctc ttgtaaaccg
    40321 tacggagata ctccagaaag accgccgcaa tcaagacaat ggcaatagta gaaacagttg
    40381 gagaaatccc caaaaccaga ccaaaggcta cacctgaaag tgagacgtgg ctaagggtat
    40441 cactcatcaa actctgacga cgcaagatga ggaaggttcc caataccggt gagaaaagac
    40501 tcatagcaat aaccgccaaa aaggcgcgct gtataaagtc gtaagataat aaactaagca
    40561 tggcccacct cctggccatt ctcatgaacg ttgaaacaac gccatggcga gtcttggtta
    40621 cggactagat gaatattgcg atccgcataa tccttaactt cttcagggtc atgggtaatc
    40681 atcaaaacag ccttgccatg atgatgggcg ctgtggtgca tgagttcgta aaattcattt
    40741 ttacttcctg catccatccc cgttgttggc tcgtctagga taaacacatc agggtcagaa
    40801 gcaaacatac gcgcaatcac cgctcgctgc ttttgtcccc cagatagaga ccccaagcgt
    40861 ttgtctcgat gttcccacat gccaactgag tccagactgg ccttgatatg ctcctcatca
    40921 tgagcattca aacgacggaa ccagcctttt ctcggatagc gacccgactt gacaaattca
    40981 tagaccgtac ttggaaaacc agcattaaaa ctggcaattt gttgaggaag ataggctatt
    41041 ctcaatttct taccttgcgt atttgtcttt gaaatagcca cctttccaat gcgtggttgc
    41101 agaattccaa gactagcctt gatgagcgtc gtcttagccg ctccattttc cccagtcaag
    41161 gtaacaaatt ccccactatc aacactataa ttgatatgtt caagaacagg ctccttatca
    41221 taatagaagg acaaatcctc taccgtaata tatctcatta tttgatttct cctactaaag
    41281 cagtcaaaaa ccgctgaatc actttttgtt catttggagt aaactgagtc gccacttgtt
    41341 cataggttaa aagtgtatgc tcatggtgat ggtggtgctc ctcagcgatt ggacgagcca
    41401 agtcagtcaa ctgataaaaa atcacacgcg catctttaga atctttagat gtttccaaca
    41461 tcccttcctt gaccaaagac ttaatggcct tggtaactgc cgcctgactg acattgagac
    41521 gacgggccaa ttctgaattt gttaaagatt cctctgacaa gagcataagg atatgctcct
    41581 gagtattggt cagggccacc tcgctagtgc aatgacctat taggatttca tgctgatttt
    41641 ccgcctgcaa aatcacctca ttcaaaaaag cattgatatc ctttgctagc tgtctcatat
    41701 ctgactcctt tccttttaga cttctctttt ttaagagaaa aatactattc tttgacattt
    41761 tgtttaccag ttaattatat cacaagcaaa aaaagagtca agaaaaaacg tgaaaactag
    41821 tttcattctt gaactcttct atattatatt atctattgaa attctttgac atctccatca
    41881 taagtcgccc aatctttgct gaaaaagcgc ttattcagat ggtaagtcgg agctggtgtg
    41941 ggattggata ggaaaggatc aactgccttg tcaaaagcca accaacccaa ccagccaagg
    42001 tgaatggtgt ccttcataaa gaaaggctcc ccgccgtcct tagaaaaatc tgctatattg
    42061 gtaaaacctt gactttctaa ctggtagcga atcttctgca ccgtttgttg gtacatatcc
    42121 tctcgtagac cagcatagtc catccatttt ttattaacag gtggaatgat aaaaatcggg
    42181 tttaccttag atttagaaaa ctgtgttaaa accaactgca agtcattata ctctggcgac
    42241 ttgagatagg taaagctttt ctgagaatcc tttaatttct tcaaatcctt cttgatctgc
    42301 tcattataga aataattttc cattcccatc tcattattgg aagtattttt ttcagcatct
    42361 gctttgacaa catcttctat tgcttgataa gaaaactggt ctggcaagat ttttaaatac
    42421 ttagctacat gcttatcgta gttaacatag cctctaaccg aaaactgacc aaaaaaggag
    42481 gcttggcgtt cattaaaacg agccaataat tcaatcattt cattgtctgc tgtcgacaat
    42541 tcttctttac ttgccaactt ctgaaccagg tccttcatag ctacgtttgg gaactgttgc
    42601 agtaagcgag tcgctgcata ttgactagcc tgatccccag attgatgttt cagaaaacta
    42661 gtcaactggt ctccattaaa atactgctgg aaggctgctg gatcatagcc atttttactg
    42721 aaccactgag gtgagataac atacacaact tgtttattct ccagctgtgg taacatctgt
    42781 tgcattccaa aatattggtt aagcgatgca gctcccccct gtcctaaaag ataaggacgg
    42841 taggaacgat tgtatttctc agctaatacc gcaggatgag caccgtcaaa acgaagccat
    42901 tcactagagc caaagaaggg aacaaaacgc acatttggat cagatagtgc tctgactttt
    42961 tgacttcgct ccttaaaact atcgatagta gtagccactg ctgaacgctt ttcagctcct
    43021 agattatgat gcatctcagt aggataaaag aaaatgagca gaaaaaccaa caaaccagcg
    43081 atcaagaccg gtccgaagat catccataag cgtttaagca ttttgtagct ccacaatacc
    43141 agctatgatt ttattagctg tattccagtc gtcacgacca aactctgtta cagggacacg
    43201 aatgtcaaaa cggttctcaa tctccacaat caactcaacc gttcccatac tatccaagac
    43261 acctgcatca aaaagatctt catccatcat gtcagaaaca tcttccataa acaactcatc
    43321 aataatttca ataacttctg atttgatatc catattttat ttccttttat tttttaaacc
    43381 atagattatt caagaatcca gaaaagatta agaatgacaa catgacaaca tggaaagtga
    43441 taaccatgcc aagcaactga atccagcgat tctcaggtag ggcagccttc cctgcttttt
    43501 tccgttcctt attgagcgtt tttttcttgc gaacccaggc atcattgatg accaagccta
    43561 gtccatgaaa gagtccatag gcgatatagt accaggtcac accatgccaa aatcccataa
    43621 tcagcatatt tacaatgtag gccatgcttg aggttacatt acgattttta aagactttct
    43681 ttctggttaa caccatcacc attcgcataa agacaaagtc acggaaccag aaggacagac
    43741 tcatatgcca gcgattccaa aactccttta aatcccttga taaaaagggc ttgttaaagt
    43801 tgatagggct acggattccc atcaagtttg agatggccaa agcaaacata gaataacctg
    43861 caaagtcaaa gaagagctcc agaccaaaag tatacataac tgccaaggca tagagattaa
    43921 agaagccacc tgactgcaag gctaaattct tcagaggagg tagtaaggtc tctcctaaaa
    43981 catgagctag gataaactta tacaaaaagc cccgcatgat atagcggaca gattcatcca
    44041 gcatatccat caactcatct cgctcaggaa tggcctgata attttcatta aatcgcttaa
    44101 aacgatcgat tggaccactc gagaaagttg gcatgaagag aaggaaacgg aggaattccc
    44161 agagggtaaa atccttaatc actccatctc tcagctcgat gataatccca accgaacgaa
    44221 atgtcaggta agaaattccc aagaacccaa gcaaagactg cgttccattg atagctggtt
    44281 gcaccttgac aaagataatc ggaagtaggg acagaaaact aactaagtag aagacccact
    44341 tgccatcctt gctttttcga taatgcttgt agaaaagcag gagcaatatt tcccagcaaa
    44401 ggtaaatacc caaggcagct agttgattgg tctttccacc caccaacatg gtgacaataa
    44461 agaagagact taccaacact tcataccagg caaagcgttt cttgaaaaag agacctataa
    44521 agatgggcaa ggttgcagca atcacataaa caaaatactg aggattgcca tatggctcta
    44581 aatgaggaag ctgttgaaaa aactccatca tctcttattc acctcgttaa tcaatccttt
    44641 gatgtcaatc tttccatttg gagttagtgg caaactgtct cggtaaagga atttagatgg
    44701 catcatgtag gacatcatga tgtctgtcag gtcttccttg atggccttgg taatatcgat
    44761 atctcgctca aactgctcac gaacaccgtc ttttaagatg acataagcca atagattttg
    44821 taccttgtgg tccttgttat agcgcggtac tgcgacagca gattcgataa agcgagactt
    44881 gttgaggttt tgagagacat cttctaactc aatgcggtaa ccgttaaact taatctggaa
    44941 gtccatgcgt ccgccgtaga gaagcaagcc ctcatctgtc atggttccca catcgcctgt
    45001 gtgataggct ggcagacctt caaactcaaa gaaggcttct gctgtttttt caggattgtt
    45061 catataacct tttgaaacag ctggcccaga aacaatgatt tctccctgtt cgccatttgg
    45121 cagtttattt ccttcctcgt caatgataaa ggttggagaa tcagccttgg tatagccgat
    45181 tggtaggcgt ttgagagtcg ctaacatctc gtctgtaaca gcaactgctg acagagctac
    45241 tgtcgcttct gttgggccgt aagcattgat gatacgggca tttgggaaac gctcgcgcag
    45301 tttttgagct gttttgaccg tcaattcttc accatcaaag tagaaatgcg tgattccagg
    45361 cattttctca ctgttgaagt attcagacaa catggccata tctgcaaagg atggtgttga
    45421 tgtccagata gcgattggca atgaaaagat agccgcaaag agttgcttaa agtcctgagt
    45481 gatgactgaa ggaagagtga aaagcgtacc accaagtgcc aaggtcggtg cccaatacat
    45541 gacagacaag tcaaaagaat aaggtggctg tgccagcatt tgcggacgac tcggtgtcgc
    45601 aaattcctta tccgtaatca tccagtttgt aaagctgagg agattatcat gtgaaatctg
    45661 cactccctta ggcttaccag tcgtaccaga agtaaagata atgtagtaat tatcatctcc
    45721 cttgactgga tgcgtgattt catagttgtt cccttgggca aaggcttctt gaacctgagc
    45781 tagatttatc attggtgtag aaacctgctc caagggaaag gctgaaatgg caataatcaa
    45841 gcttggctct gctacttcta aaatagctga aactcgctcc aaggccgaat ggctatcaat
    45901 tggaatgtag gcatgacctg acttagtcag cgctacaaag gttgccaaca tttcatattc
    45961 ttggccacca aaaacaacca caggagactt ttcaggcaag cctagttggt caatgactgc
    46021 agccaaacta tccgaatcag cctttaaatc gccataagtg tgttcctgcc ccaaaacatt
    46081 atagacagga tagctaggct gtgtctgagc aaaatgctca atggtttcaa tcatatctgc
    46141 tattggttta tttgacacaa tagggattct ccttcaagtt aaaattcatt atagataaag
    46201 cttccttgac cctgaccaag atagctaaag aagtaaagca gccctagaaa gataagaaaa
    46261 tacaaggctg tccgaccaag aaagaggtac aattcttttc tctgtttcat caagaaaaac
    46321 cattcatttc tgtaattttt cgctaaaata agagtgattc ttactagctt atttttctac
    46381 cattgtacca ctttatatag tatcttttca attgtttacc gtatgtttcc aatagatttc
    46441 agcttatttt aaggattatg cggtttttct atatctattt caaaagaaaa aagcctgaga
    46501 ttttcatctc aagctctagc aataatagtt attttctaaa ctaaaaaagt gagaatacaa
    46561 gcacggccaa ggctgctccg ataacagggc ctacaacagg aatccaagcg taagaccagt
    46621 ctccgtctcc cttgtttgga attggcaaga tgctgtgcat gatacgaggt ccaaggtcac
    46681 gagctgggtt caaggcataa cctgttgtcc cacctagtga tagaccgata ccgacaatca
    46741 aagttcccac tgcaaaggtt ccgatacctg cctgaaagtc gtaaagaccc aaagcaaaga
    46801 ttgtcaacac caaaacaaaa gttccaagga tttcgctaat caagtttgat acagtatcct
    46861 tgatggctgg tccagtactg aaggttgcca ggatattgcc tgcattttct tctgcctcat
    46921 agtgaggttt gaattgcaac caaaccaaaa tctgacccag catggcccct gcgaactggg
    46981 ctaagatata aggcaaaacg gaagcccaag gcaaaccacc ttttaaggcc acaccgatgg
    47041 tcacagctgg gtttaaataa gctggactga gcttgccaga tacaaagact gcaaccgcaa
    47101 ctgcaatccc ccaacccata gtaatcacaa tccaacctga gctattgctc ttggttttag
    47161 gaagaaccac acctgcaaca acaccatttc ctagaagaat caggattaaa gtccctagaa
    47221 attctccaaa taattcattc atcatctttc tgtctccatt aaaaagaagg gacgggcgac
    47281 aaggaatgct gccctccacc tcttttattt tttcttaatt ttttaattct gctaaatcgt
    47341 tgttagcgag agctgcttcg acatcagcac ggtaagttgc tttttcttct tctgtccagt
    47401 catagaatcg tcccatttca tccaaaattg gctcaacgat actatccaag ctatcacgca
    47461 taaagagcat gtgattggta cgacgaagaa ggaagtcaac tgggctaaga gtcaactcat
    47521 tgcgcattgc atagtgaagg gacaaggtgt ctgccaagct aagacctggc gcttgttcca
    47581 agctgtgagc aagtgcaaag accttcggtg catttgaacc gtaaagattt gctaggtaat
    47641 gagcttcctt gctatccaaa ccacgtgaaa ctccaagttg cgcaaaggct tcgatttctg
    47701 aatccacatt tgctgggttc aattctccac ctgaaacagg gtaagtttta gaattgatca
    47761 atttaaagct acggtcaaat tctgctttga ggatgtcaac cacgcgctcc atagctcctt
    47821 cagccatctt acggtagtct gtgattttac caccagcaag agtcaagaga ccattgtcat
    47881 cacggtccaa gctagaccca cgagaaactg cagatggatc caaatgtttc tcagatgtgc
    47941 tactttcaag cttgctgaca gcagactcaa catcttcacg tgttttttct ttggagagat
    48001 aagattcaac agtcgcaatc aagttgtcaa agctttcatc actgatggta ccgttatttc
    48061 caccattata gtcagaggca ctgttccctg caatcaatgg acgaagacct gcccagctgc
    48121 tttcgatatc atcaatggtg atgttggatt ctgggaagcg gttgttgaca atgccaagta
    48181 gataatctac atcttcttga gttacttttg gatgctccaa atcacctgtg tagtctgtat
    48241 cagttgtacc aaagtaagtc ttgttttcac gtgggagaac aaagaccata cgaccgtcac
    48301 ccaaacctgt gtcgaagtaa actggctgtg aaaccttgat tttacttgaa tccactacca
    48361 agtgaactcc cttagttggg cgcatttgtg agaattgcgt tcccttatta gacaaattac
    48421 gtactttatc actccaagga cctgttgtat taataaccag acgggccttg atttcaaata
    48481 cttggtctgt caagagatca cgagctacaa cacctgtaat cttgccactt tcgtcaaaga
    48541 ggaagccttc tgccttcacg tggttggcaa tgagggcacc gtcttggttg gcacgtttga
    48601 tgttttcaat cacgagacgc gcatcgttgt tacggaagtc aagatacact ccacctccta
    48661 ccaagccttc cttcttcaag tttggctggc gttccaagac ttctttcttg ctcaaaacct
    48721 tgttcgcagt tggtgtgttg ctcacacctg ctaaaaggtc gtacaagtcc atggctactt
    48781 taagacggaa gaggctaaag gttgctccat cttcatcgta aactggtaag agcattggat
    48841 ctggttttgg aatgtgtgga gcgatttgtt gaaccactgc acgttcagaa accgtatctg
    48901 agaccacttc tacgtcgaat tgtttgaggt agcgaagacc tccgtgaacc aattttgttg
    48961 aacgactaga tgttccttct gcaaagtctt gcatttcaat caaaccagtc tcaagaccgc
    49021 tagctgccgc ctgcaaggct acaccagctc ctgtgattcc tccaccgata atcaagaggt
    49081 ccagggtgcg ttcctgcatt tttttaattg acaattcacg tgttttcttt gaaaattcca
    49141 tatttacaca ctttctaaat aaatcgcttt attctgccag tattagtcgt ctacttccgc
    49201 aaagacttga gttgctttca cagccttctt ccagcccttg tagagttgtt ccttgcgaga
    49261 ttcattcata gatggctcaa agagttctcc tgtctcgttc aagagtttca actcgtccaa
    49321 gtctttccag taccctactg ataaacctgc taggaaggcc gctcctagag ctgttgtttc
    49381 caagttttta gcacgtgcaa tatcaatgcc taaaatatcc gcctggaact gcatgaggaa
    49441 gttgttcatg gctgcaccac catccacctt caatacttga atggcagtct gagtatccac
    49501 ttgcatggtg tcgatgatgt cacgcacttg ataagcaata gattgcaaag tcgccttgat
    49561 aaagtcttct ttgcttgttc cacgagtcaa accaaagacg gaaccacgag cattttggtt
    49621 ccagtatgga gcgcctagac ctgtaaaggc tggaacgaca taaacttcat cgttgttgtg
    49681 agaatcacga gcgtattttt cagattctgg tgaattttca accatgcgaa gaccgtcacg
    49741 aagccactga atagcacttc ctgcgatgaa gatagaacct tccaaggcat aataaacctt
    49801 accgttgatt ccgtaaccaa tggttgtcaa gaggttgttt tcagacaact gcatctcttc
    49861 cccagtattc atgatgatga aagagcctgt tccataagta ttcttaacca tacctggctc
    49921 aaaagccaac tgtccaaaga gggctgcttg ttggtcccca gccatacctg agattggcac
    49981 ctctccaccg tagaaatgga atggagctgt cttgccgtag atttcggagt tagaacgaac
    50041 ttctggaagt atagccttcg gaatgttaag gatttccaaa atctcatcat cccatttgag
    50101 ttctttaatg ttataaagca tggtacgagc tgcatttgag tagtcagtca cgtgagccgc
    50161 accgtcagtc aatttccaaa ccaaccaagt atcgatagta ccaaagagca attccccttt
    50221 ttctgctcgc tcttgagcgc cttctacatg atccaaaatc caacgaacct tggtagcaga
    50281 gaagtaagca tcaataatca aaccagtctt ttcatggaat ttttccacat aaccttggct
    50341 ttttagttgc tcagccaaag gtgctgtctg gcgtgactgc caaacgatag cattgtagat
    50401 aggaagtcct gttttcttat cccagacaac cgttgtttca cgttggttgg taatcccgat
    50461 tgcctcgatt tgatttggct tgacgccact ttcgatgaaa gcacccgcaa taactgactg
    50521 aacagagttc caaatttcat tggcattgtg ctcaacccaa cctgcctgag ggaaaatctg
    50581 ggtaaactct ttttgactcg agctaacctt ttcccctttt ttgttgaaaa tgatggcacg
    50641 agaacttgta gttccctggt caatggccat gatgtatttt tcttgtgaca tgtactgtcc
    50701 tcctgataaa gatcttgagg tgtttcctct ttacacttac tagtatacaa aataaagcgc
    50761 tttctttttt atcaactttt tttaattttt aaaaaaatgt gaggagattg tgtgaatttc
    50821 acaaaaaaga cctggattaa ccaagccttt taagtgaata ataactgacg aatccctgcc
    50881 aaatcttcca tatccaagtc attttttaaa taatagactg gggtctgttc cttcttatga
    50941 atcgggttat tggtaaccag caaatcataa tgccgactag ggtcataagc ttcaatggta
    51001 ataaaacgat tgtattccaa ataccgtttc aaaatggctg ccatccttga aaagacaaga
    51061 aaaccagatg tcaaatccag accaatccgc atatgctggc caccgttttc agccatatat
    51121 tcgattaact ggagccattc ccagagaatc ttcttatcta aatctgtccc ctgttgaaaa
    51181 gcaggtagag catgaaaaat ctcctctgct gtctctttaa aatcatgttc catcagtaaa
    51241 tatggatgac gattctctaa ctggtacttg tagcgatcct gtaaaatata gcccttatag
    51301 agatagactt gagcacaaag ctgactgagt tcataggtga catggtcctc tgtataatcc
    51361 cccaatagtt cctccttctt catttcttga atcaattgcg tcagtaaatc tgccaactgc
    51421 cctccaaaac caagaatata ttccatagta tgaagaggaa gaatgcgatg agataggaga
    51481 aaagagaaga atatcatcat ctcaccatcc tcaactccta gtggaatatg ttgcccagca
    51541 aaaaaggacg gaacctttct cagcaaacga agatagaaga tattgtcaaa ataccctcgc
    51601 attttctctt ctatgacttg aaactgacaa gcattgaccc gaagacgttg ttgactgatg
    51661 tgagcccaga gaaccaagtc caatttctgc cccacagaca aacttgcacc gcagatttcc
    51721 tctaaattgg caatctcctg ttttctctct ggtttctgca tgtgaccttc ccattcctga
    51781 ctcgaccaga cctttcggaa aagacagaaa tagaaatagc gaatctgatg ctctggacct
    51841 cgccaacgtc cattttggat ggataaatca aattctgaca aaatctgatt taaaccagcc
    51901 aagtgacgac caagcgtagc ctcgctaatc accaattctt gagccagctg atgggctaaa
    51961 aactgttggt ggtagagaag ataaaccaaa atctggtatt taacagcact ctccaaaaac
    52021 aagctccgaa tatctctccc cttggtagct gcaccgatag acagacgcag attttcatct
    52081 tctgagtgaa tagccagctc taagccacta tccaaagcct tgtcattgag cagggtgaca
    52141 tatttggtta gggttgcttt tgaaaatcct gtttcttcca ttacagcctt gacggtcgtc
    52201 tgagactctt gtaatagaaa ggaaaggatt gaaaattgac cacactcggc tttctccatc
    52261 aaatctccta aatacatttg ttaccccttt cattttctac cttaagcata gcataaatct
    52321 tacaaatgct aaaataatct gtttctcttt ttattttcat gctgatttcc tggtccatta
    52381 tcctgaaaat cagtaaacac acggctcccc ctttgggcat ttttatgcta aaatagtagc
    52441 tatggataaa attattaaaa ctatatcaga aagcggagcc tttcgtgctt ttgtccttga
    52501 tagcactgaa accgtccgca ctgctcaaga aaaacatcaa acccaagcta gctcaactgt
    52561 agcgcttggt cgaactctta tcgccagcca gattctcgca gccaatgaaa aaggaaatac
    52621 caaacttaca gttaaggtgt tgggatctag ctctctaggt gctattatca ccgtcgctga
    52681 taccaagggg aacgtcaaag gctacgttca aaatcctggt gttgacatca aaaagactgc
    52741 gactggtgaa gtcctagtcg gaccttttgt tggaaatggt caattcctcg ttatcacaga
    52801 ctacggtact ggaaatcctt acaactctat aactcccctc atctctggag aaatcggtga
    52861 agaccttgcc ttttacctta ctgaaagcca acaaacgcct tcagcggtcg gcctcaatgt
    52921 ccttttggac gaggaagaca aggtcaagat tgcaggtggt ttcctagttc aagtcttgcc
    52981 aggagccaag aaagaagaga ttgctcgctt tgaaaaacgc atccaagaaa tgccagctat
    53041 ctctactctt ctcgaaagcg acgaccatat cgaagccctc ctcaaggcta tctacgggga
    53101 cgaagcctac aagcgtcttt ctgaagaaga aatccgtttc caatgtgact gtagccatga
    53161 acgctttatg aacgctcttg ccagccttcc aagctcagac ttacaggaaa tgaaagagga
    53221 agaccacggg gtagaaatca cttgtcaatt ctgccaaact acttacaact ttgatgaaaa
    53281 ggacctggag gaactcattc gtgacaaatc ttaatacacc ttttatgatt ggcaatgttg
    53341 agattcccaa tcgtaccgtt ttagcgccta tggctggcgt gaccaactca gcctttcgta
    53401 ccatcgcaaa agagctcgga gctggactcg ttgtaatgga aatggtctct gacaagggaa
    53461 tccaatacaa caacgaaaaa accctgcaca tgcttcatat cgatgagggc gaaaaccctg
    53521 tctctatcca actttttggt agcgatgaag acagcctagc acgcgcagca gaattcatcc
    53581 aagaaaacac caagaccgat atcgtcgata tcaacatggg ctgccctgtc aacaaaatcg
    53641 tgaagaacga agctggtgct atgtggctca aggatcctga caagatctac tctatcatca
    53701 acaaggtcca gtctgtcctt gatatcccac ttactgtcaa aatgcgtacc ggctgggcgg
    53761 acccatctct tgcagtagaa aatgctctcg ctgctgaagc tgcaggtgtt tctgccctcg
    53821 ccatgcatgg ccgtacccgt gaacaaatgt atactggcca cgcagacctt gagacccttt
    53881 acaaggttgc ccaagctcta accaagattc cattcatcgc caacggtgat atccgtactg
    53941 tccaagaagc caagcaacgc atcgaagaag ttggtgctga cgcagtcatg attggccgag
    54001 ctgccatggg aaatccttac ctcttcaacc aaatcaacca ttactttgaa acaggagaaa
    54061 tcctacctga tttgaccttt gaagacaaga tgaagatcgc ctacgaacac ttgaaacgat
    54121 tgattgacct caaaggagaa aacgtcgcag ttcgtgaatt ccgcggcctc gctcctcact
    54181 atctccgtgg aacatctggc gctgccaaac tccgtggagc catttcgcaa gctagcaccc
    54241 tggcagagat tgaagccctc ttgcaattgg agaaggctta atagtttaaa acccgtaact
    54301 ctcttaaaga gcctcttgaa tgccgccatt ctttcctcat caaaaaaact ccgtagtctc
    54361 tagcgctata aatccggcta gagattacag agttattttt taatctaaac ttcctacaag
    54421 ggtatattat ctactgaaag gatatggtat ttgtagggaa tactttaaag agttcttaca
    54481 ggaagtcagt attaactagt tatattaggt ttagtttacc cattcaccat tggcattgac
    54541 tctatagcta tctacagttg tgttgactgc aagggcacct gagccattga catagtacca
    54601 tttatctgat actttgaacc attggcttgc tttcatagca cctgatgctt caagatagta
    54661 ccaggtatct ccatctttca cccaatctgt tgccattgaa ccgttagcgt tgaggtagta
    54721 ccatgaacca ttgttttgga gccatcctgt tgccattgaa ccattagcgt ttagatagta
    54781 ccatgaacca ttgttttgga gccatcctgt tgccattgaa ccattagcgt ttagatagta
    54841 ccatgagcca ttgttttgga gccatcctgt cgccattgaa ccatcagtat tgtagaagta
    54901 ccacataccg ttttcttgtt tccagcctgt ttttggagta gatggttgtg ctggtttttc
    54961 agtttttggc ggttgctgtt gagtcaagcg attatattct tcttctgatc tacgagcata
    55021 gtcttcttca gcttgttgat cagctggttt ttctgctttt ggttgttcag ctggattctc
    55081 tggttttgga gctggagctg gtttttctgg ttttggagct ggtttttctg gttgaggagc
    55141 cggcgctggt tgtggttgtt cagctggttt ttctttaact ttatcttctt ctgctgcttt
    55201 tcgtttagct tcttcttctg cttttttacg atctgtcttg attttttcta accttgtagc
    55261 ctcagcttgt ttactctcaa cttccgcttt tgcttgctta actttttcct cgtttcgagg
    55321 ttccttagct tcctctttta ctagttcaag ctccgctttt ttaacttcca catcggactc
    55381 agcaatttca agttcaagcg ttttgtaagt attggttggg tagttacgac gatcttcttc
    55441 tttttgatcc tcggcttttt tcttagcttc ttcaaccttc ttctcagctt ctgcaacctt
    55501 tttttctggt ttcagggatg ggcttggaag agtttcttca cctacgctag aatctgaaga
    55561 cttcgcatca ttttcttttt tatcaggtgt tgctggctct ccaagaactc ctcgttttgt
    55621 ccgcttcttt ggttcatctt taactttagc ttcttcttct gcttgttcac gatctgtctt
    55681 gatgttttct aaccttgtag cctcagcttg ttcacgatct gtcttgattt tttttaacct
    55741 tgtagcctca gcttgtttac tctcaacttt cgcttctgct tgcttaattt tttcctcgtc
    55801 tcgaggttcg ttagctttca cttttactag ttcaagctcc gcttttttaa cttccacatc
    55861 ggactcagca atttcaagtt caagcgtttt gtaagtaatg gttgggtagt tacggcgatc
    55921 tttttctttt tgatcctcgg cttttttctt agcttcttca accttcttct tagcttctgc
    55981 tacctttttt tctggttctg ttgataatgt atctttttta aactgctcaa aagctgcggt
    56041 taactcttct tttgtttctt ttgtttttga cgtcaactca gcttccgact tctcttctaa
    56101 aacatttaat tcatacaaat acttcgtttt aattttgctc aactttttgt tgaagtcggc
    56161 attttgggta tgttgaactt ttttcaaatt tttattgaca tccttcaata tactttgtag
    56221 atgcgactcg acttcatcag catacttctt cgatatatct tgcccactag atgtaaccgt
    56281 ggagttattc ccacttctaa ccccttctgc atggactact cctcctaaga acaagctggc
    56341 aactactaca ctagctactc caatactaaa tttacgaatt gaataatgta cttttctttc
    56401 gctttttgat gcaaacataa ttatttcctt ctatattttt tctttaacct tactatatca
    56461 cttcaatatg aactgtatat aaatcgaatt ttgtatttat ctctttatgc ttccatttgg
    56521 gattataact tcatgtaata gcttttcctc ttcagctatt cgtcgataca aaataactgc
    56581 ataaactgga aaaactaaaa caaaagtcac ataagcatga ctcaacaagg tcaagccaat
    56641 caactcagga agaatattta aaaagtaatt aggatgtttt actgtcctaa acaagatatg
    56701 atctacatat ttgtgattat tgacaagcat aagcttcact gtccaaatat ctcccaacaa
    56761 gtgaatcacc aacattaaca tcagcataga aaaaataagc aagactaaac caaccatgcc
    56821 catgccatca aaaattgtct tgtgcaccat tgcctcaacc aagcaagaga gataaaaaac
    56881 aatatgagcc atagttaatc gttttgtatt ctcaactcca aattctttcc cgccattgct
    56941 aaggattcgt ttctcattct ctatcgaacg ctttaaaaaa atcaatcgaa taaggaatgt
    57001 tactaaaata atcgctaata ccatattagt atcctttctt ttatctacac aaagaataac
    57061 acacttatgt taaccctata tgaactttaa taaaaaacta atctgtctac aagctaatct
    57121 taaattccat accgtgttca taagggagaa aactataatc catttgatag ctttctaaaa
    57181 tattattcac aatgtaaaga cccaaaccgg aactttcatc cttatctgtc acgatttgag
    57241 aatgatagaa tatatcaaat aaatgttcta gttcttggtc acttagaggc gcacatgtat
    57301 ttttgataga gagatagcca tcttgctcgg atatgattac gcgcccattt ttatctgaat
    57361 atttaattgc attactaatc aggtttgtca aaaccttatc caatgcccta agactcatga
    57421 cgaccctggt agcatctgtc aattgatttt caattgtaac acctattgaa tgagctaatt
    57481 cttgataacg tgataaaata tctactaaaa ctggcttaac agtcaaggtc tcacgacact
    57541 ctgtccactc ttggaattta gaagactcca gtacttcttc caataagtgg ctcatctggt
    57601 caatcttatt tatactcttt gcaatatatt ttggatgatc tttgtaatct ccaatattat
    57661 gctgcatatt ctctaggata attctaagac tggctaaagg ggttttcaac tcatgtgatg
    57721 ctccgcggac aaaggaaacc ttttgatttt gcaattttac aatttgctca ttacgacttt
    57781 ccaactcatg aataaccttc aacaagtgct catacatacc attaatctgt tttccaactt
    57841 caccaacttc accaacttca tctttcctac tttcatcaaa acgaatattg tcatccaaat
    57901 cttgcatttt actagtcact tctgaaatgt aaaaaagagg attgagcaag cgtttagtat
    57961 aaaaataaga aaaaacaaag gaaaaagcaa ttgtaaccaa aaatgtatat gggagataca
    58021 aaagcaaaat attctttgct tctttgtaga catccacccc gtgaacaaat tgcacggtta
    58081 cctgtttacc atctgctgta ctaacagaca tatctaacat cacgatataa tttgatagct
    58141 ttccatcttt aatatccaag tcatgcacaa gagggagccg cttatctaca atatctcttt
    58201 taaggtgagc agatatggtc aaggactttg aataagactg gagtaagctt ggaatttcat
    58261 cagatgtctt agtctttaaa tactccgtaa acactcttgc gctctcatta aacttttccc
    58321 cctccagttg aatataataa aaaggaaagg tcaaataaat agctatatga atgactagac
    58381 caacaccacc tagaattgca aaacttctta aaaaagactt ggttaataat ttaggatttt
    58441 ttatcataag ctaatcttat acccaacatt tttcacagtc acgatacaat ctaaagctaa
    58501 ttttttgcga agagtacgaa tatagacatc aacgacccta tcacaaggta aatcagctac
    58561 atcttttgaa atttcttcca atatctgctc tctacttaaa acttgatttt tatgctgaat
    58621 caaacacttt agtaccagta attcctttgg cttgagatca atttcttcat ttttataatg
    58681 tgctttgtaa gaggtaaaat ccactgttac atcctgatat cgccaaatat cctctatgac
    58741 gtagtaacgt ctgataagcg ccttaatacg cttgacaagc agtaccaaag aaaaaggttt
    58801 tgtcacatga tcatcagcat agagatcaaa tacctgtgac tgagtagttt catctcccag
    58861 agcactcaag acgatgacag gaatatcgtg cttttgattg atttctttta acacttcaaa
    58921 accactcttc ctaggcatca ttaaatccaa taccatgaga tggataggga gatcttgaaa
    58981 tttttccaag acctcttgtc catccttagc cataatgaca tgataaccct cttctgtcag
    59041 aaatgctgca attccttctc taatcatttc ctcgtcatct gcaactaaaa tgttcatctc
    59101 tctccctttc tactaccaga actccataca tctatttcct gtatgctatt tgaaaatttc
    59161 ctaccagcct atcatctatg ataatagaat ggatttcatt tatccgctac tttttgtcaa
    59221 caacaacgtc aatacaagaa aatcattcat cttgcagctt atactcttcg aaaatctctc
    59281 caaaccacgt cagctctatc tacaacctca aaacagtgtt ttgagcaacc tgcggctagc
    59341 tgcctagttt gttctttgat tttcattgag tttcactcca ctgtgactta tggtcagatg
    59401 ctgatacttt tattctttta tgcaatatca aattttaact ggcctgcttt gacaccaatc
    59461 ttaagtgtgc tgcctgccac taaatctccc ttaagaagaa gttctgccaa cttgtcctcc
    59521 acttctgttt gcagggttct gcgaagtggg cgagctccca tctctgggtc atatccttga
    59581 tttgctaaca atttcagagc tgaagcttgt aatttcaagt caatgccttt ttcagccaaa
    59641 cttgccacta aaggcttgac cataatcttc accacttcct gcatatggtc actagatagg
    59701 ctatggaaga ccaccttctc atcaatacgg ttgatgaatt ccggtctata agcttttttc
    59761 agttcttcaa acatgcgttt ttccatattt tcctggtcaa aacgaatatc cttagcccca
    59821 aaaccaacag tcttatcatc acgaagggca gtcgcaccta ggttcgatgt cataatgata
    59881 atggtatttg aaaaatcgac cttgcgtccc ttgctatctg tcaagacacc gtcatccaga
    59941 acctgcaaga gaacattaaa gatatctggg tgagccttct ctacctcatc aaagaggaga
    60001 acggaatagg gtttattgcg aaccttctct gtcaactccc caccttcttc gtaacccaca
    60061 tagcctggag gagctccatt tagacggctg gctgcgaatt tctccatata ctcactcata
    60121 tcaaagcgga taagggctga ttcgtcatca aagagaactt ctgccaaagc cttggccaac
    60181 tcggtcttac cgacacctgt gggtcctagg aacataaagg aaccgatcgg acgcttgtga
    60241 ctgcgaattc ctgactgatt acggcgaatg gcacgactaa tacttgaaac agcttgatct
    60301 tgaccgataa cccgtttatg gagttctgct tcaagattta gatatttctt agcgtcagtc
    60361 tgagtcagtt tttgaactgg gattcctgac aagcgactca aggtggtcaa aatatcagac
    60421 tctgtcacca agtctttgta gacaggtact tcctcttctt ttgcgattag ctgggctgcc
    60481 tgtttccact tgccatccat cagggccttg tcagctggac tcaaatctga atcgtctgct
    60541 tttacatact ttgccttatt ttgcactgtt gctgctgctt cgtccaagag gtcgatagca
    60601 gagtctggca agtgacgact ggttaaataa cgatgagcca tcttaaccgc tgtttcaacc
    60661 gcttcatctg tgatttgtac acggtgatgt ttctcataag tcgccttcaa accttgtaaa
    60721 atagtcatac tatctgccac acttggttct tcaatcgtca ctttagcgaa acgacgagaa
    60781 agagccgcat ctttttcgat atgtttttga tattcttcct gagtggtggc accaaccgtt
    60841 ctcaaagttc cacgcgccaa ggctggtttc aagatattgg ccgcatccag agtcgaatca
    60901 attccgctac cagaacccat gatggtgtgg agttcatcga taaagaggat gacttggcca
    60961 tcttcttcaa tatccttgat gatattattc atgcgttctt caaagtcacc acggaagcgt
    61021 gtccctgcaa cgacattcat caaatcaagt tctaacacgc gcatcttagc catttccgca
    61081 ggcacgtcac cactagcaat acgctgggca agaccaaggg ccagagctgt tttcccgaca
    61141 ccagcatccc caaccaagac agggttgttc ttagtcttac ggctcaagat ttgaatcata
    61201 cgtgagattt ccttgtcccg accgatgact ggttctaact tgccagaacg cgcttgctct
    61261 gtcaaatcat gcgtatagtc ctcgagacca ccactaggag tctgcggcat gcccatcata
    61321 ttggccatag aattttgctt gtcagctact gtacgatggc gttggcgtaa agccttgaga
    61381 tcttcacgag tccagcctgc acgttcttct aaatttcgac gaagggcagc aatcttgacc
    61441 tgatctttct tgtcttcata agaaaaacca gccctctcca agatacgagt cgccaaggca
    61501 ttgccatcat gcaaaatcgc atagaggacg tgctctgtcc ctagtacctt agcatggacc
    61561 actgacgcta catactctgc ttcatcaaaa agaacctgca aacgacggga gaacggcaat
    61621 tccgtaaagg tttcatcctg gctatagtcc gtttcagtca gttccaaagc cacctcttct
    61681 aaacggtcca tctcatacgg ataatcattt aaagttgccc ctgctacact ataactgtga
    61741 ttagacatgg caatcaacaa gtgccacgac tctagataac gagctccaaa atgtccagca
    61801 accatgtagg cactttcgat acattcattc aatgcttttg aatagttcat cttacttccc
    61861 ttttctatct acctcttgta tgacctgacg tagcatgttt gctcgaacaa ctggagcttc
    61921 ttctcctaaa acgcgatcca aagctactga ttctagcaaa ttcatctcct gcttggtcat
    61981 caattcctgc tcaaccaaaa gctggagaat atcctcataa atttcttgac tgactcgctc
    62041 accaatcgag taaagcagat cccggagcat ttcatgatga ctagaaaact caatccgtcc
    62101 tatacgaatg tagcctccgc caccacgctt actttcaacc aagtagcctc tactttccgt
    62161 aaagcgtgtc ttgatcacgt agttaatctg actaggaaca acctgaaagg tatctgccaa
    62221 ctgactccgt tgcaactcca cgataccaga ttgatctaaa atcgccttga tgtaggcctc
    62281 aatatgatcc gatgtatttt taaatctcat aacaaaccca cctctctctt taaaccttga
    62341 ccttgtttga ctattatacc gaaattttct catttttaaa agaaaaaggg cgctggtaaa
    62401 ggataatctt caccaactcc ctatttttct acttatctaa gcctaattct gccaagattt
    62461 gacgtttgta ggcaatcttt tggacttcct tgtcctcatc ttcagaccaa tctagtttaa
    62521 tttctgaaac aatctgccca gggcgatttt tcaagatata gatgcggtcg ctgagattga
    62581 gggcctcctc aatactatgc gtgatgatca gagttgttag ctgcaactgt ttgtgaatct
    62641 caagatacca agcgtggagt tccatctttg tcatctcatc caaggcgcta aaggcctcat
    62701 ctaagagaaa gagcttgtgc ccaaaaaggt aggtccggag taaggctaca cgctggcgca
    62761 tcccaccgct aagttcatga ggatacttgt ctcttacagc tgtcagctgg aaggtcgcaa
    62821 gaattttatc cgctcgggaa atagcttctg ccttatccac cttttgaatc aagaggggca
    62881 gaatgatatt tccaagcacc gtcttgtgct ccaagagcag atccttttgc aacatataac
    62941 tcacgcgccc cttgggattt tcttcaccat caaggacaat tctccctgac tgaacttcta
    63001 aaatcccagc gattagatta aagagggtgg tctttccaac accacttggg cctaggatgg
    63061 aaaccacttc gcctgaagtc acctgtaggt tgatatcctc taaaatcctc tcctgaccat
    63121 aggcataact gacgtgctct agtctaattt ctgtcattat ttcacaaatt cgttggtgaa
    63181 gcctttgtct gtcaagtctt ctttaaggat accattttct ttatcccatt tgtagaaagc
    63241 attccagcga gctgcgtcaa attgacccca tttttccttg tcgcttgcgt attcttttga
    63301 caagtatttt tgagattcga tgacaaagtc acgtttttcc ttgagttcag gtgcattctt
    63361 gatgagaata tctgcagctt cttctggatg ttccatggca tattggtagc cttttttgat
    63421 ggcttggatg actttgcgag cttcttcttt gttatctttc agatagtcgt tgtttgcgat
    63481 gataactggt gaatagtagt caaactcctt gacatagtct ttcaagtaca tgaagttagc
    63541 atctacacct tgagatttag caaggatgcc atcccaaccg tagtaaatcc aagcagtatc
    63601 aaagacgcca ttggcaatcg gtgtgattga gtttgagtcg ttatttggta ctttttcaac
    63661 cttctcaaag tctccacctt gagattctac caaggttttc aacatagcaa gttcagttgg
    63721 gtcattccat gtcccatatt tcttaccaac caagtctttt ggactgctta cattatcaga
    63781 tttacgagag atgattcctg atgtattgtg ttcaacaata gctgcaacgg cagtgattcc
    63841 tgctcctttt tccaatttct tagccatgta gtcttggaaa tacactgcaa atggtgcctt
    63901 tccgttgata accaagtcag aagaactttc ttctggtggc aatttcaaat caacatccac
    63961 tccagcttct ttgaaataac ctttttcctt ggcaacataa agccctgtgt ggttggtatt
    64021 tggtgtccag tctaggataa agtcaacctt cttaagttct gcctctttgt tgtctttaga
    64081 agcagttcct tgaccacagg ccacaagcac aacagctaca agagctgtta caagcgttaa
    64141 aaacactttc catgttttct tcattttgat ttcctctttt ctttttcaga aacattctaa
    64201 ttctacgaac gtttccattt aatcacatat ttttcactga tatcgaccag cttcataccc
    64261 aaaagactga taatcgacac cagaataata atggcaaaca tggtatcata ctgaaacagt
    64321 tttttagact gaatcatata aacaccaaga ccttcaaaac ctcccaacca ctcagatacc
    64381 acagttgtga taaaggcgta ggagacactg accctcagac ctgcataaaa gtaaggcagg
    64441 ctaactggga ttttaaaatg ccacaggatt tgccaaggct tggcccgcat cagactaaac
    64501 aaggtcagca tatccttgtc gcaatgccta aaaccgtcca aaatactaac gatgatggga
    64561 aaggttgtcg ttaagataat caagacaatc ttgggcaaaa tcccataacc tagccacaag
    64621 accaggatag gagctatggc aatggtcgga atggtctgaa tgaccaccat catagggtaa
    64681 atcaggtcat tgagccaagt caaactatcc atgagcacag ccataagaca ggcaatcaaa
    64741 actcccaaaa tcagccccag taaagccact ctcaaggtcg cccagctatg gtgccagaga
    64801 aattctctgt cacgaacaaa gggctggaga atttcaagag gtgtcggcag gataaacttg
    64861 gggagaagtt taagaaaacc tgctaactgc cagattgaca atactccgag aaagcccaat
    64921 agactaatgt gtcgtctcag tatacttctc aagtttctca tcaatactta aaatctctcc
    64981 tacatttatt ttgacattgg caaagacatt gtctgcctcc tgccctgcca cttccagcgc
    65041 ttcttttaga atgcgcataa gctcatcaaa ctccccttcc aagaccgttt caaatggtgt
    65101 cactaccatc gtcacttctt gagtttgcag ataagcaatg acctgatcaa taacagctat
    65161 ccgatcaatc ccctgtacta ggggtaaaac ttgcaaggca atgcttgctt tcataagaac
    65221 ctcctcttct cgttttcctt tttaaaaaaa gaaaaacctt taccatacat ggaaaaggtg
    65281 caaaattaga ctaagtatcg ttccctccgc tggcattacc cagatcaggt gcggtcgaag
    65341 tttaacactt cctctcagac tgtacacaga ctcccatata ttatatgtat atatgatagc
    65401 gcaaaataag aaaaatgtca aggaaactgc ttacagaaaa gagcaggaaa tttctcctac
    65461 tccaattttc tatactcgtt ctccatcact gtttactctg tagccatcca ccgtcgtatt
    65521 aacagctaag gcgcctgaag agtaagaata ataccactta ccagagacct ggtaccagcc
    65581 tgttttcatt gcccctgaac tacccagata ataccacaaa ccattttcct ttaaccatcc
    65641 tgtctgcatt tcaccagata atttcaaata ataccagcta gaaccgtctt tcagccatcc
    65701 tgttgattta gaaccatttg atttgaaatg ataccaacta ccatttattt tcttccaacc
    65761 gacagttgaa ctactatggg atccatagct agagatgttt cctgattgat tctgataatt
    65821 ttgtgaagaa gtcactccct ctagctgtat atagcgacga cttccgttat aagccgtata
    65881 actcaaccac ttgtagccgt ctttttcgag aatttgatca taatgaacgt tctctccagg
    65941 ataatagtaa tcaatcacag ttgcactaac taggggttca gttttgatag cagacttggt
    66001 cttaaaataa tgagttccgc ctgttgaaga aagaacagaa ttacctagag gatttttatt
    66061 cacagcctcc aattgaacat aacgatagct tccattatag gcagtataac tcaaccactt
    66121 atagccgtct ttttcaaata tctgatcata atgaaccttc tccccaggat aatagtaatc
    66181 aatcacagtt ccgctagcta ggggttcagg tttaatagca gacttggtct taaaataatg
    66241 agttccgcct gttgaagctg aggattgact attcccaacg ctgccgccat ccaaatcttt
    66301 aaaatgaata aatcctgtca tcgtgtttgc ttttataact cgtttattat aggattctgt
    66361 ataaccatag ttatattcct caatctcaat ctgatctccc attacatttg acacccaggc
    66421 aacatgacca taagttcctg cagtagacca agtaatggaa ccaatcgtcg gtgtattatc
    66481 tacacgataa ccttcccgac gagcacgatg tccccattca ttcgcatttc cataagctgc
    66541 cggcatttca aaaccattga cattactcaa acgaaaggct acaaaagaag tacactgacg
    66601 agaatacatg cgccactgat caatctcctg gctcccattt ttataataag caggataatc
    66661 atccccacgc gcaatcgatc catttcctct ggaataggca tagacactat caccagctgc
    66721 tagcatcaat cctactacta aaaaaggaac aagcttttta actgacatct tcaagtaata
    66781 acttgttcct cttgctataa acggtaaaat tttcattctt cctccttgaa aaataatata
    66841 aagcgatgat tgccttcacc taaattattc ggagaaaaaa gaaaaagtga gaaaatttct
    66901 cactttagtc aagataatga atcaaattct tttctgtaag aatatctgag taagtaaagg
    66961 attcaacgta aacattaact tgtttatctc cttccacatc cccaaactcc acaataaata
    67021 gggatggata aacttcaatt agcttaccca atctattttt ttggcgctta cgaccattct
    67081 ccaaagtcat ttctacgact tgtccctcat gtgccttgat ttcttctttg atttttttca
    67141 tcttggctac atctgtaaat gcatctgaca tcttatgcct ccctctttga gatacttgaa
    67201 aatttattgt attctttttg gaaaatcaat tccactgttc cacgagctcc actacggttt
    67261 ttctcgataa taacttccac cttattattt gggataccct cctcttcttc accaccacgt
    67321 tcatagtagt catcgcgata gagaaaagct acgatatcag cgtcctgctc aatagaccca
    67381 gattcacgaa tatcagacaa gaccggtctc ttgtcctgac gttgttctac accacgagaa
    67441 agctgactca gagcgattac tggaaccttc aattccttgg ctagtatttt caactgacga
    67501 gaaatttcag aaacttcttg ttgacgattt tctcgaccag ttcccgtgat aagttgcaaa
    67561 tagtctatca aaatcaaacc aagatttcca gtttcttgag ccaatttacg agaacgagaa
    67621 cgaatctctg taatccgaat acctggcgta tcatcgatat agatactggc gttagctaga
    67681 ttaccctgag caatagtata tttttgccac tcctcatctg tcaattgccc tgtacggata
    67741 gaatgtgact ccactaagcc ttctgcagct aacatacgat ctaccaagct ttccgcaccc
    67801 atttcgagtg aaaaaatagc aaccgttttg tccaacttag tcccaatgtt ctgagcgata
    67861 ttcaaggcaa atgctgtctt accaactgct ggacgagctg ctaagataat caactcctcc
    67921 tcatgaagtc ctgttgtcat atgatccaaa tcacgataac ctgtcgcaat acctgtaata
    67981 tcggtcgttt gttgcgagcg agcttccaga tttccaaagt tgagattcaa cacatctcga
    68041 atgttcttaa acccgcttcg atttgcattt tcactgacat caatcagccc tttttctgcc
    68101 tgagcaataa tttcatcagc tggttgtgac gcttcgtaag cttggttgac agactctgtc
    68161 aacttggcaa ttaaacgacg tagcattgct ttttctgcaa caatcttagc ataatactcc
    68221 gcattagcag aagttggcac agaattgaca atctcaacca agtaagacaa gccaccaata
    68281 ttctgtaaat caccttgatt atcaaggata gtacgaaccg ttgttgcatc tatggcatca
    68341 ccacgatcgg ataaatcgac catggcttgg aaaatcaaac gatgggcata cttaaaaaag
    68401 tcccgagact caatgtattc tcgcacaaaa acaagtttac tctcatcaat aaagatagcc
    68461 cctaaaacgg attgctcagc taagatatct tgaggttgta ctcgtaactc ttctacttct
    68521 gccatcagac ttcccttcct tttacaatct tgtcaagaag gtgtaaactt atccttcttt
    68581 cacacgaaga ttgattacac ttgtgatatc ttgatagatt ttcactggca catcaatcaa
    68641 accaaccgct cgaatcggag cttgtacttg aatatgacgt ttatcaatct taattccaaa
    68701 ttgcttttgc aattcttctg caatcttctt attggtaata gaaccaaagg tacgaccatc
    68761 tggaccaact ttttcaacaa attctacaac agtttcttct gcttcaagtt gtgctttaat
    68821 tgcttttcct tctgcaatca tctcagcgtg agctttttct tccgattttt gtttaccacg
    68881 aagttcacct acagcttgag cagtcgcttc tttggctaga ttctttttga taagaaagtt
    68941 ttgcgcatac cctgttggta cttccttaat ttcgcctttt ttaccttttc ctttaacatc
    69001 tgctaaaaag attactttca ttcttctttc tccttttcct ttatttcatt taatacaatt
    69061 tctgtcagtt tttcacctgc ttctgacaag gttacatctt taatttgagc tgctgccaaa
    69121 ttaaagtggc ctccaccgcc taactcttcc ataatccgtt gtacattcag tttactacga
    69181 cttcgagctg agatagagat aaatccttgt gtattcttcg caagaacaaa actcgcttca
    69241 atacctgaca tggctaacat ggcatctgct gccttactaa taacaactgt atcatagcat
    69301 ttcgtgtcct tagcctctgc tattagtaca tctgaaccta atttacgccc ctgtaaaata
    69361 agttcattga cctcacgata ttcttcaaaa tctgtcgcag cgatttcctg gatagcaata
    69421 ctatcacttc cgcgcgttct gagatagcta gcaacatcaa atgtccgact agttactcgc
    69481 gaggtgaaat ttttagtatc caacatcata ccagccatca aaacacttgc ttgcatacga
    69541 ctcaaacgat ttttcttaga attctggaac tgaatcaatt ccgttaccaa ctcactggca
    69601 ctacttgcac cactttcgat ataagtaatg accgcattat ctggaaaatc ctgatccctt
    69661 ctatggtggt caataacaat ggtttgggta aataaatcat aaaattcttt tgataatgtt
    69721 aaggctgtct ttgaatggtc tacaagaatc aacaaagaac gattggtcac catccccatt
    69781 gcatccttaa cagacaacaa cttcgtaact ccttcttttt ctatgaatga aacagctcgt
    69841 tcaatatctg gagacatttg ttcttcatca taaagagcat agctattttc aatcacattg
    69901 ctggcgaaca actgcatacc tacagcagag cccaaagcat ccatgtctaa atttttgtga
    69961 ccgactacaa aaacctgatc tacactccga atcttatctg aaatagctgt catcatagcg
    70021 cgcgtacgag tccgtgtacg cttgattgaa gcagcagacc caccaccaaa ataaactgga
    70081 tttttcgttt cgtcgttttc cttaacaacc acctggtcgc caccacgtac ttcagccaag
    70141 ttcaaattga gcaaagcaac tttccctatc tcatcatgat ttccatcgcc ataagaaaat
    70201 cccatactta aggtcaaggg caactgtctc tgtttcgact cttctctgaa agcatcaata
    70261 acagaaaatt tatcattcat caagccctca agcaccgtgt agtcagtaaa tagataaaat
    70321 cgatccatac ttacccgacg agaaaacatc atgtattttt ctgaaaactc tgatataaaa
    70381 ttagctacaa aactattgat ttgactaata tctgactcag aagttgcatc ctccaaatca
    70441 tcataattat ccacagagac aatcccaatc actggtcgac ttgttaccaa ttcatctgtt
    70501 atggcttgtt ccctggatac atctacaaaa tacaaaacac cggaagaagc atccatatga
    70561 acagcataac gcttctcacc aagcttggca taagtagacg gatttcctac tgaagccttg
    70621 ataatcgttt gaacagcttc taaatcaaaa tcaccatctt ccttggtcaa aatcaattca
    70681 gcatagggat taaaccactc aacctctcca gaagataaat tcaatttcat aacacctaca
    70741 ggcatctgtt ccaatagagc tgtcaaactt tcttccgctt ggtggtttac atactgtatc
    70801 tgttctacat cactccttgt ataatgcact ctcagtttct taaataaaaa aacatagcct
    70861 cctacaaaaa gaaacaaaat taaaaccgtc aacagattat tattaacaaa aataatgaaa
    70921 gtggataaga ctccaaacgc aatcaatcct actagaatag gaaaaattgg acttacataa
    70981 aattttttca ttcaaaacct cttggcaccc attataccat aatacccctc aaaaagcgac
    71041 tttttaaaag tgtaatcagt aattctatca attataagaa aaaggtagtt tacaattcag
    71101 taaacctacc tttacacata ttgaaattaa gattctttaa cctctaacaa accaatttcg
    71161 ccatcctcac gacgataaat cacattggtt gtctgatctt caacatccac atagataaag
    71221 aaatcatgcc ccaataaatc catttgtaga attgcttctt ccaaatccat tggttttaaa
    71281 tcaatttgtt ttgaacgaac aactttagac tggacaatat ttgaatcttc caccaaagca
    71341 tctgtaaata attgaccagt tgctacctta tttttatttt tacgctcgat ttttgtttta
    71401 tttttacgaa tctgacgttc aattttatca gttacaaggt caattgaacc atacatatct
    71461 tgagatacat cttctgcgcg gagagtaata gatccaagcg gaatcgttac ttccacttta
    71521 gccgtttttt cacgataaac ttttaagtta attcgggcat ccaactcttg ttctggttgg
    71581 aagtactttt cgatcttttc gagtttagaa actacataat cacgaattgc ttctgttact
    71641 tctaggtttt caccacggat actatattta atcatatgag taccttcttt ctaaacattt
    71701 ttgtttttat tataacgctt tcattctatt tttgcaaatt ttttcctcat cttacaaggg
    71761 aaaatgtttt tacatcctta gcaccagctt cttccaacag tttcttaaca cgatttatag
    71821 ttgctcctgt agtatagata tcatctataa gtaggatttt tttaggaata gtgactccac
    71881 ttttaataaa gaaaggaagt tctgtcccca agcgctctga acgattttta gaagaactgg
    71941 ctctctcttc tcttttctct aataaatcca gatactcaaa acctgctgcc tctaccaagc
    72001 cctcaacctg attaaatcct ctattagcat atctatcagg acttagggga attacaacaa
    72061 attgatactc tttgtacttt ttcaactcct cacttaaaaa tgaagcgaaa acttttctta
    72121 acaggaagtc tccatcaaac ttataccgac tgaaaaaatc cttcatagct tgattgtaag
    72181 taaaaatcgc tctatgactg actccaactc cttctttaca ccaaagttga caatattgac
    72241 actttgttga caactctgtt ttcatacaat ttggacagtt ctcttcccca attctttcaa
    72301 aagtagaatc acagtctgaa caaagacaag agtcatcatt cctcagaagt aagagactac
    72361 taaaagttaa aacagtcttc atagtctgcc cacataacaa gcacttcata gaccagcctc
    72421 cttattcatc atctgaattt ccttaatcgc cttcttgatt gaagcattta acccatcatg
    72481 gaagaaaagc aaatctcctg tcggtctatc catgcttcgt ccaactcgtc caccaatctg
    72541 aatcaaacta gacttggtaa acaaacgatg attggcctct actacgaaaa catccacaca
    72601 agggaaggta actccacgct ccaagattgt cgtactgata agtattgtca gttctccatc
    72661 tcgaaaagct tgtacttgct ctaatcgatc ctctgttaca gaagatacaa agccaatttt
    72721 ctcatttgga aattgctcct gtaagatttc ttctaactgc tcccctttct taatttctga
    72781 agcaaaaatg agtaacggat aagctgtctt tctctgcttc tcaatatagg actttaactt
    72841 tggtgacaaa cgattcttgt ctaagtagcg attaaaatcc gataaccaaa ttggttttgg
    72901 aataatcaac ggatttccat gaaaccgtct cggtaaattc agtcttttta gttctcctaa
    72961 acggaccttt ttatctaact cattggtcga agtcgctgtt aaaaagattc tcaatccatt
    73021 ctcctttaca ctattcttga cagcgtggta aagcattgga ttatcaacat aaggaaaagc
    73081 atctacttca tccactatca gcaaatcaaa agcttgataa aacttcaata actgatgggt
    73141 tgttgcaaca actagtggtg ttcgaaaata aggttccgat tctccatgta gcaaagctat
    73201 cccgcaagaa aaatcctgtt gcaggcgctt gtacagctcc aaacaaacat ctatgcgagg
    73261 actagccaaa cacactgcac cacccgcatt gatcacttta gccactactt gataaatcat
    73321 ttctgtcttt ccagctcctg ttaccgcatg aactaaggtt ggcttttgct tgtctactgc
    73381 ttgaagcagt ccctctgaca ccttctcttg aaaaggagtt aattggccgc gccatttgag
    73441 aacatcttgc ttcggaaaat cctcctgcgg aaaatagtat aaagtttgat cacttctgac
    73501 tcgcttcatc agcaagcact ctctacaata gtaagcaccg atgggcaaat accattcttc
    73561 tagaatagta ctattacaac gttgacagaa aagtttcccc ttctcctttc tcattgctgg
    73621 aagtttctcc gccaactgac gttcttcttc tgttaattca ttctcagtaa ataaacgacc
    73681 gagataatct aaatttactt tcatacttct ttattcgtaa aaactagcac tttagatgat
    73741 tttttagtac aattaaatca tggaatttag aacaattaaa gaggacgacc aagtccaaga
    73801 agaaatcaaa aaatctcgct ttatctgcca tgccaagcgt gtttatagcg aagaagaggc
    73861 tcgtgacttc attactgcca tcaaaaaaga acactacaaa gcgacacata actgctctgc
    73921 ctttattatt ggagaacgta gtgaaattaa acgtacaagt gatgatggtg agcctagtgg
    73981 tactgctggt gttcccatgc ttggggtact agaaaatcac aatctcacca atgtctgtgt
    74041 ggtcgtgaca cgctactttg gtggtattaa actaggcgct ggaggactaa ttcgtgctta
    74101 cgccggcagt gtcgccttag ctgtcaaaga aattggtatt attgaaataa aagaacaggc
    74161 tggcattgct attcaaatgt cttatgctca gtaccaagag tacagtaact tccttaaaga
    74221 acatgatctc atggagctgg atacaaactt tacagatcaa gtcgatacga tgatttatgt
    74281 tgataaagaa gaaaaagaaa ctattaaagc tgcacttgtg gagtttttta atggaaaagt
    74341 cactttaact gaccaaggtt tacgagaggt tgaagttcct gtaaacttag tgtaaacaat
    74401 gaataataca gcgtttcgtt gacattctca caactacttt agcgagcaaa ataaaaagat
    74461 gcgtaccaaa atatactaga aaatgaagca attcaaacga aacctgatat cgttttcctt
    74521 cacacctatt tactagaatt agctgaacgc aatcacttga aaattaatga ctttgatcta
    74581 tgatatatag aaatcctatc gcttcgatag gatttctata ttttacaaat ggtatggata
    74641 gcgttatact aaagatatct tatacaaaga ggtattcata tgtctattta taacaacatt
    74701 actgaattaa tcggtcaaac accgattgtt aaacttaaca acatcgtgcc agaaggtgct
    74761 gcagacgtct atataaagct tgaagcattt aatcctggtt catctgtaaa agaccgtatt
    74821 gcccttagca tgattgaaaa agctgaacaa gatggtattc tgaaacctgg ttctactatt
    74881 gttgaagcaa caagtggaaa cactggtatt ggactttcat gggtaggtgc tgctaaaggg
    74941 tataaagtcg tcatcgttat gcctgaaact atgagtgtag aacgacgtaa aattatccaa
    75001 gcttatggtg ctgaactcgt cctaactcct ggtagcgagg gaatgaaagg tgctattgct
    75061 aaggctcaag aaatcgctgc tgaacgtgat ggtttccttc ctcttcaatt tgacaatcca
    75121 gctaatccag aagtacacga aagaacaaca ggagctgaga tactagctgc tttcggtaag
    75181 gatggattag atgcctttgt tgctggagta ggtaccggtg gaacgatttc tggtgtttct
    75241 catgcactca aatcagaaaa ttctaacatt caagtttttg cagtagaagc agatgaatct
    75301 gctattctat ctggtgaaaa acctggtcct cacaaaattc aaggtatctc agctggattt
    75361 attcctgata cacttgatac taaagcctat gatggtatcg ttcgtgtaac atcagatgac
    75421 gctcttgcac tcggacgtga aattggtgga aaagaaggct tccttgtagg gatttcctca
    75481 gctgcagcta tctacggagc catcgaggtt gccaaaaaat taggtacagg taaaaaagtc
    75541 cttgccctag caccagataa cggtgaacgt tatctctcta cagcacttta tgaattgtaa
    75601 ccgtccaata acgaagtata ttgaaaaatc tccagactag agaactcacg gatagttcct
    75661 aatctggaga tttcttattt gcacttttct tgtacaactt tagtccatgg taaataagcc
    75721 tctaaaacct ctttgtttac gagagtttcc acgtttggaa gacattctag aagataggat
    75781 agatatttct cactatttat aatggattga aataagatat gaacaaatcg attaggacat
    75841 gatggtaaag cgtaatccct tgtttctcag ctttcccaga caaaaaagtc caatagtaag
    75901 tcagctgact atcactctct agcaccctat aagaagtttc atccgcatga agtaaggact
    75961 gcgtcaatag tctctctcgc aagaggttat aaaggggctc caaatagtat tgactcgcct
    76021 tgatatgcca attagcaatt tccttacgtg tgattggtaa acccatctta gcccaatctt
    76081 cttcttggcg ataattgggt accttcagat taaacttctg atggatggtg tgagcgataa
    76141 tagaagctga gccaaggcta tgcgccaaag gggctttagg aataggagct ttcacaagct
    76201 tatccagatg attatctttt actcgttatg gacaatgcta tatggcataa atcaagtacc
    76261 ttaaagattc cgactaatat tggttttacc tttattcctc catacacacc agagatgaac
    76321 cccattgaac aagtgtggaa agagattcgt aaacgtggat ttaagaataa agcctttcaa
    76381 actttggaag atgtcatgaa tcaactccaa gatgttatac aaggactgga gaaggaggtg
    76441 ataaagtcca tcgttaatcg gagatggact agaatgcttt ttgaaaacag atgagtataa
    76501 aaagaaagtc ctcatttcaa tagaaatcac gactttctga tggatttata gtaaaatgaa
    76561 ataagaacag gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttaaaagc
    76621 agaggtgtac tattctagtt tcaatctact atatttttgg agtgatagaa aagcccttca
    76681 taagctagtc tacttgttca ggtgcgagag ctttgacatc cttttctgta cttagccaag
    76741 tcagttttcc gttctcaaag cgtttatata gtagccaaaa tccttgacca tcccagtaaa
    76801 gggctttaaa gcggtcttta cgtccaccac aaaagagaaa gacttgaccg gagaaagaat
    76861 ccaattcaaa gtgggtttta actacatagg ctaatgagtc tattccctgc ctcatatctg
    76921 tcttgccaca aacaaggtga acttgaccta aatcacttag ttgaattatc atagtacaat
    76981 acctttcctc cgataattat tttttatcta gtatactgga agttggggaa ttaggataga
    77041 taccttgtta tgacgcgctt actatgaatt ttaagtatag tctcctaaat gcacttagcc
    77101 cttattatag ggctttttgt tttaattatt ctaatcgagt gagactgggg aaaaaacaat
    77161 ttcaggaaaa atctaagccc tatacaaaaa aggaagcaat ttgctccctt tctattatta
    77221 gttattcaag gctgctgcca ttgtagctgc aacttcagct tcgaagtcgt ttgcagcttt
    77281 ctcgatacct tcaccaactt caaagcgagc aaactcaact accgaagcgt taactgattc
    77341 aaggtatgct tcaactgtct tgctgtcatc catgatgtaa acttgtgcaa gaagtgtgta
    77401 agcttggtca actttagtgt tatcaagcat gaagcgatcc attttacctg gaataatttt
    77461 gtcccagatt ttttctggtt tgccttctgc agccaattca gctttgatgt cagcttcagc
    77521 ttgagcaata acatcatcag ttaattgagc ttttgatcca tacttcaagt gtggaagagc
    77581 tggtttatta accattgcac ggctttcgtt gtcttggtcg ataacgtgat tcaattgtgc
    77641 caactcatct ttaacgaatt gctcatccaa ttctttgtaa gaaagaactg ttggtttcat
    77701 cgctgcgatg tgcattgaca attgtttagc aagtgcttcg tctccacctt caacaactga
    77761 aataacaccg atacgtccac cgttatgttg gtatgctcca aagtgttgtg cgtctgtttt
    77821 ttcaatcaat gcaaagcgac ggaatgagat tttctctccg atagttgctg ttgcagatac
    77881 gtatgcagct tcaagagttt cacctgaagg cattatcaaa gcaagagctt cttcattgtt
    77941 agcaggtttt ccttcagcaa tgactttagc tgtagtattt accaattcaa cgaattgagc
    78001 gttttttgca acgaagtcag tttcagcgtt tacttcaata actgctgcaa cattaccgtt
    78061 aacataaaca ccagtcaaac cttctgcagc aacacggtca gctttcttag ctgccttagc
    78121 catacctttt tcacgaagca attcaatcgc tttttcgatg tcaccgtctg tttctacaag
    78181 cgctttttta gcgtccataa caccggcacc agatttttca cgcaactctt ttacaagttt
    78241 agctgtaatt tctgccattt taattctcct atattttttg aaaataggag agccgggcta
    78301 agccccgccc tcctaggtaa ttactatttg tataaattaa gcgttgtcac cttctacaac
    78361 ttcaacgatt tcttcaattg aatctgcttg agtttctgaa gctgcaaatt ctgcttcaac
    78421 tgctactgca tcctcacctt gacgtccttc gataatagcg tcagccaatt tagctgtgat
    78481 caatttaaca gcacggatag cgtcatcgtt agctgggatg attacatcga tatcatctgg
    78541 atcagtattg gtgtcaacca tcgctacaac tgggattccc aattttttag cttctttaac
    78601 agcgatttgc tctttatgtg ggtcaactac gtacatcaca tctgggatac gaggcatatc
    78661 ttcgatacca cccaagaatt tttcaagacg cgcacgttgt ttgttaagaa gtgcaacttc
    78721 tttcttagga agaacttcga aagttccatc ttcttccata cgtttaattt ctttcaaacg
    78781 agcgatacgt ttttggattg ttccccagtt tgtaagagtt ccacccaacc aacggtggtt
    78841 gatgaagtat tgacctgaac gtactgcttc ttcagcaact gcatcagctg cttgtttctt
    78901 agtaccaacg aacaatacaa ctgcatcgtt agctgctgca tcacgcatga agtcgtatgc
    78961 ttggtcagcg tattttacag tttgttgcaa gtcgataacg tggattccgt tacgttcagt
    79021 aaagatgtac ttagccatct taggattcca gcgacgagtt tggtgaccaa agtgtacacc
    79081 agcctcaaga agttgtttca ttgaaattac tgccatgagt atttctcctt tttgtttttt
    79141 tcctcttctt gacttcaact cgcaaaacga cccaagggca actgcttcac aattcatcaa
    79201 gaatgagtat tatcgttcac acgacaattt tcattctacc atacttttcc aatattttca
    79261 agctattttg atataatttt taatagggat tgtcacggta aaacctgaaa agagggctct
    79321 attcgagtcc ctctgtaaat taatctgcat aaatatatgt aacaaaacct tcagaagttg
    79381 ttgttggatt gaaccatcca cggtgatttc caattgtacg attacctgca taatttgatt
    79441 ctgatacttg gatacgtgtt gttgattcaa cagctgtaac aaccgctacg tgaccatatc
    79501 caccatcatt ccaacatgca attgctccaa cttgaggtgt tgaacctgta cggaaacctg
    79561 ctgctgctgc acttgtagcc cactgtgctc cattacccca gtagtctcca gcccaaggtg
    79621 ccaatgtttt tactccccat gtacattctc caattggata acttgaagcg tttgtactgt
    79681 atgttggacg aacttttgca cggacaggtg ctgctgcaga ttcagatact gcttgcactt
    79741 gagctgttaa gttagtgttt gctgaagcaa gtactgattg ttgttggcta gctcgttttt
    79801 ctttataagc tgcttctgct accgcagctg cacgagcctc tgcctcagct gctgcttttt
    79861 gctctaatag acttgctttt tccccttcag ctgtcgcttt ctcagcagca agacttaatt
    79921 cagcagcttt tagttctgcc tgtttcgtag tcaatgcttg agcatcatca gccaattttt
    79981 gttgattagc aattacagta ttgatagcat cattatttgc tacttgtttt tcagaaatag
    80041 cttttttatc tgccttttgt tgttctaaca ttttgttgtt tgcagatacg atttcactca
    80101 ttgcagcaac acgtgaaata gcttctgtaa ttgattttga gtttacaatg gtattgatat
    80161 agctagttac ggctccattt gtttgagcac tacgagcttg tttttccaac gattggttac
    80221 gagaaacaat gtttttagaa agttctgtaa tctcaccctc gagtttctta gattctgctt
    80281 gtaatctatc attttcagct tgcaagttag actgctcagc ttgaatagct gatacttgct
    80341 cctgaatttg gtcaacttgt ttttgggctt cttgttgttg tgctgttaag ttactaattt
    80401 tattatcttg agcagcaatt ttgtcatcag tcgtttctgc atgcgcagtt gttaaaacag
    80461 ctacttgaga aaccattact gtacttaata aaagtgacgc taagattttt ttcttcatat
    80521 tacgtagata ctccttcttt taaagacaat actagtatac caaaaaaagg cctaataaat
    80581 attacgcctt tgttacattt atatgtcgtt cttatagata atatttttca aaaataaatt
    80641 gaaaaacagt aatccataaa aaatttaaaa tcatcgtcgg taccaagcta tagactataa
    80701 aaatcgacat gctatctact gtcaacccta ccataaaagc caaaagataa ctacccattt
    80761 caaacaggaa tgtcagcaca atcatagcta gcattcttgt ccaacgattc aacaaaataa
    80821 cactattcaa tttatgaagg aaggctccca ataagataaa taagagagtt gtaatcccta
    80881 ttagatggaa aaagtaaaca tcataaacca agcctataac aaaacaatag actaggtaga
    80941 gatactctga tacttctatc gtctcaaata agagaaatag aaaaagaaaa tgactagcca
    81001 aatgtacatg ggggaaaaat gagcccagaa gctggctaat atgggcgtca attagaacaa
    81061 agaaaggaag caataaaaat actccaactc gcttcaactg tctcattatg aattccccac
    81121 taattctatc acatctacat tatgagtatc tgcactcaat ttaacagtta cttctcgtgt
    81181 caaatagtct gtactatgcg ttgtggcaac cacttcacca acaggaatat cagcaacgtt
    81241 aaagtttcct aatccaccag tagtcacctt atctcccgca ctaatatcgc tattactatt
    81301 taattggcta attttaagaa cgtcattttc cttgtcatag ccaataataa ttccataaat
    81361 tgtagtagag ccatgttgaa ttttaacaga aatcttatca gcattttccg tatttgtcag
    81421 aaggttgact atagtagagt tctcctctac ttttgaaaca ctcccaatca agccaccatt
    81481 tgcaatagct aacatgttct cagaagcacc ttttgatcta cctgcatcta aggtcaactc
    81541 ctgcttccaa gataccggag aacgcataat aacatctgct gctaaagtct ttgtggcttg
    81601 caatttagac ttcatatcaa gcaattggcg cagttgttca ttttctgtct ttaaactttc
    81661 cacctcattt gatttaactt ctaattggta aagctgtttc ttcaaacttt cattttcatt
    81721 atatgttcgt gtcaaatgag ccaaatctga tttgacagaa tcaaaccact gaaaaggttt
    81781 ttgtacaact ctatcaacca atgagattcc atctcctaat tttgtcacaa ttgtacttga
    81841 ataagtcgtc gctaagagag ctgacacaag cagaacagtg acaaaaacaa taatgacata
    81901 ttttgatttt ttaaaacggt tcatatccct acctttatat caaaaactgt tacagtaact
    81961 ttttatcaat tcctgaaagc tactaagatt ttaagaaaaa taaacaacaa ccaagtacga
    82021 gaataacaag aatggtcagc gtatccttta gagtccattt caattgtcgg tattgacttc
    82081 tgccttttcc accctgatag ccacgcgctt ccatagcgat agccaaggaa tctgcacgtt
    82141 ttaaacttgt cgcaaaaaga ggaatcaaaa tgggaatcat cgactttact ttttgaacga
    82201 tgcttccttc tccaaaatcc actccacgag ctttctgtgc attcataatc cgcgtcgtat
    82261 catccatcaa ggttgggaca aaacgcaaac tcatagacag catcaatcca atttcatgaa
    82321 ctggaacttt cacacgcttt aaaggtgcta ataaagcttc gacagctgat gccaaactta
    82381 aaggcatggt tgttaaggtt aacaaagttg aaaagaaaat aatcaataca aagcgacaaa
    82441 aaataatccc agcttgttgc aaagcataat ccgtgattct cacaaacgaa aactcaaata
    82501 aaacattccc attagaaatg aaaaatagtt gaaaaatagt tgtgaaggca atcaagaaaa
    82561 acatagactt caagccctga ataaaaaatg aaagagatac tcctgacaag gcaataaata
    82621 tccctgtcgc tataaaaaga atcagattcg tcaaggggtt attagcccaa aacacaatca
    82681 aaatcagtag catcatagca agcaatttgc tacgtggatc caatcggtga acaatcgaat
    82741 cccctgggat ataacgccct aaaatcatac tatccattta gcgactcctt gaactcctct
    82801 atcttaatcg gtaatcgttt aaatgacacg cctctatcag ccaatcgttt acaaaaggcc
    82861 gtaattttag gtactcccaa ctgaacttct tccataaaaa caacgtcttg aaagacatca
    82921 cttggtttgc ccccctttac taaacgtccc ttttccatta catagacttg attcgcatat
    82981 tcagcaacat catccatcaa atgcgttacc aagacgatgg tcatccctga ctggtggagt
    83041 tttttgaaca gggtcatcaa ctcctttctc cctagaggat ctagaccagc tgttggctca
    83101 tctaagacta atatagctgg ctccatggca agtatgcctg caatggcaac acgtctcatt
    83161 tgtccccctg acagctcaaa cggactacga tcaaaaagtg attcatcaat tccaaccaga
    83221 gccagtttct cacgcgcagt cttcacagca tcttcttcag aaactccaaa attttgcggt
    83281 ccaaaagcaa cgtccttcaa aaccgtttct tcaaaaatct gattttcagc aaactgaaat
    83341 accaagccaa cctgttttct aatttgacga atatctttat ttttagaagt cgaggtgatt
    83401 aaggtatcaa aaaccctcac actcccttga cttggcacca ataaaccatt taagagttgt
    83461 aaaatagttg atttaccact acctgtgtgc ccaattaaag ctgtataaga gccatcttca
    83521 atcgtcaaag aaacatccga caaagctgct gaagctaagg gagtaccttc ttgatatgta
    83581 aaattcacat tttctagagc aattcccata gcttatcctc tagctcactt tctgtcaaat
    83641 aattttcagg taaattatag ccattatggc tcaaagattt ttttaattga ttagcaaaag
    83701 gatcgtctaa tccaatttga tctaaatcat ttcgagagaa aagctccctt ggactactag
    83761 ttgattcaat ttcccctttt ttcatgacca atacgcgatc actcatggcg acttcttcca
    83821 aatcatgggt aatagaaatg accgtcatat catagtcttt tcgaattcct tttactgtcc
    83881 caataagttc tctacgcccc tcaggatcca acatactcgt tgcttcatct aagattaaaa
    83941 tagctggtct taggactaca acacctgcaa tggccacacg ttgcttttgg ccacctgata
    84001 gacgcgctgg ctctctcttt ttaaagtcca acatgccaac taaatccaga gcttcttcta
    84061 ctctcttttt catttcttga cgagaaagtc cctgattttc caaaccaaaa gcaacatcat
    84121 cttcaacagt cgctccaaca aattgattgt ctggattttg aaaaaccata ccgatttgac
    84181 gacgtatatt ccaaacattt tcctcagtca aacgttggcc atcaattaca atctctccgg
    84241 attctgcttc cagtaagcca tcaattaatc gaaccgtcgt tgatttacca ctaccattat
    84301 gccctacaat cgaaagccat tctccacgtt tcacgtgaaa cgtaatatcc ttcacatcgt
    84361 agtagttctg attttcttta tagcgaaaag aaagattttt tacatcaatt attgatttca
    84421 tttcgaacca aatgtccctt taaatacata ggcactaccc ttgaaatagt catagccaga
    84481 gtagatagtg aaaaataagg ctacataaag tagaacttga ccaagcaaag tccaatgtaa
    84541 tagcaagaaa ataatggcaa acatctgact aaaagtttta atttttccag gcattgctgc
    84601 tgctaaaatt gttccaccag tttcaaccaa taaaagcctt aaacctgtca cagctaactc
    84661 acgacagata atcactgcaa caatccaagc cggagccata cctaactcaa tcaacataat
    84721 aaaagccgac ataactagta acttatccgc cataggatct gcaaatttac caaaattact
    84781 gaccacattc catttacgag ctaaatatcc atctaaatag tcggtaatac tggcaacagc
    84841 aaagataata gctgcaacta tatgactctc tatcgaattt cctatcgtta aaataaagat
    84901 aaaaataggt ataaagagaa ttcgacctat tgttaagaga ttgggaattt gttctttttt
    84961 cattcgtttt tccttaattt ttagtaaagg ttacagtgat ttgtccagtc tgagctgtta
    85021 atttcgataa atcaacagtc tgattatcta ctgtcaaatc aacacctttt acaacaccta
    85081 acgtaattgt tacaggactt ttagttgcaa ctgttgcttc tgcacttttc ttctttggcg
    85141 ataaggttac accgccctca agttcgcttt ctgaaacact gacccaactt gtaacatctg
    85201 aaactgccaa ttgcaattta actgtttcct tacttgtctt ataagcgatt tctacatgat
    85261 ttccttcgcc tgatacactt atagctgatt ctatactaga agaactacta cttgaggagt
    85321 ggggaacaga gctagttgaa cttgttgatt gaaccacact gtaattagaa agagaaggct
    85381 cctctggttg agtttgaata tagttccaaa cataataagt cacaaaaatt aaaatcgata
    85441 aagcaaaaag gataaaataa aataaaggta aaaatgatgt ttttttcttc tttttcttac
    85501 ttgaacgtct acgacctgtc aactcatctt catcaacatc tacttcctca taagtaatca
    85561 tactcccaga atcataagca tccaaaacaa tttggtcatc taactcaaca gcccatgcat
    85621 attttttcaa gaaagaacgc gtgtaaaaag gacttggaag ttgatcgaaa tcgtctgctt
    85681 ccattgcttc caacatatct aactggattt ctgtcttttt ctgcaattca tctaaactca
    85741 atccctgatt gattctagct aatcgtaaaa cctctccaat tgtttttttt ctcatacttg
    85801 tcatcccttc tttctagtgt ctattataat aggttactac gatgggaata ttgtaaaatc
    85861 aactatatca ccatcatcta ttaaatgatg tccagcatca aggacatcct ctaaagtaat
    85921 ttcctgtaaa attttcggca aatcaaaaat tgtctcacca ttttcaaaag catcatattg
    85981 cgttgcaata aattcaagag agttcatgct actgaaaaat tcgccaaaca tctctctttt
    86041 gataatatct aaatgttcct ctgtaatatc taaatccttt gtaaaattac gaatagcctt
    86101 cctaaattga tgagacaaag caactggctc tttcgtatcc attgtcaaca tgacaaaatg
    86161 aaagcgactt gttacttcaa cttccagaga taaggatgca tcaattttac ctgattcata
    86221 acatttttga aaacgatccg aagtccaacc aaacatcatt gcaaacaata actttaataa
    86281 aatatgatgt cgatagcaat ccgcttcaga aacttctcgc ttacctctaa ctccaatcgc
    86341 tagtttggga gaagatactt ccattctcat actatctgtt ggctttacag gctgtaaaaa
    86401 caacttttct cttgctactt cctgaaaatc tgaatctttc agttctttgc tttcaaaata
    86461 gtcctgtact cgctccacat caaaattacc aactaaaaac agagacatgt ttacaggttt
    86521 gtaaaacttt gtaaaatttt cttgcaaatt agttagattg atttgggaaa tggactcctc
    86581 acttccaact atatcagttg ctaaaggtgt accaggatac aaattcgcta aagttgaaaa
    86641 gaataaacac gaatctggat catcttggta catttctcgt tcttgctgaa taatatcctg
    86701 ctctgtcaga atggaagctt cagtaaagtg tgctgatgtt accaattcat caagtaaatc
    86761 taaattttct aaaaaataat ccgttgctga aaaaagatag tttgtttttg taaagcttgt
    86821 aaaggcatta ctatctgcac ctagactcgt aaaagccgac atcaaatcac tagaatcttc
    86881 tctctcaaat aatttatgtt caagaaaatg agcaattcct ccaggatatt gttttacatc
    86941 tccgtcaact tctgtgacaa acgtatctac cgaaccaaac tgtacagtga cactcccgta
    87001 aacctcttta aattcctttt taggcaaaag agcaactatc aatccattgg ccaaacgagt
    87061 tcgataaacc ttttctttta cagctggata gtatttttct tcaaaaacaa cctttgtcat
    87121 tctattcctt ccataaagta aatcgcttgt agtttcacat tattagctac tctacaaata
    87181 gcatctttgt caatctgttc aagctttaca atccaacttt taaagtctgc tgaagatttt
    87241 ccaaataagg cattttgata agcacgttca atcaatgaag attgattatc ttgagaaagt
    87301 aacaacgacc aacgaatcat ttccttggtc tgatttaact caaactctgt aaaataacct
    87361 ttttttaaat caagcagttg attattcatc attttacgag cctggttacg attttctcga
    87421 ttgataccag catacatcct caagaatcca ctaaataaat caagctcact tgaaatggta
    87481 taagctaatc cagcattttc acggacattt gtaaagagct tagaatgagc aaatccacca
    87541 agtaaaccat tcattacaat catgggtaaa tgttgctcat caccatattt agaacggtaa
    87601 tgataaccta attccaaaat ggattgtccc acatttttcc gaaccatacc ttcctgaagg
    87661 atattagaat aaggttgaca atactgaacc ttcacatctc cttttcgacc tttaaagcca
    87721 aatgattcta atacattttg aatttcaacc tcattaaaat cacctaggaa aaagaaatct
    87781 attcgatcat tggctaaaaa ttcttggaaa caagaataag aactttgtgg agtttcagct
    87841 aaaatacgat ttcgtaaatc actatattcc aattgaagac gttcatcatg aaaaaacaat
    87901 ttatccaatt ctttatgtgc aaaataaaaa gaatcatcca tatcagctgc taaacttgct
    87961 agcaattgtt ttttctcaat ttcaaataag gccggatcaa acccattatc aactactacg
    88021 ggtgaaaaaa gagtttcttt tacaagttcc aaaatctgag aggttagcac gtttttccta
    88081 cttaaaaact catcacgaac ataggtaaat gtcaattcta taatgtggct ttgccctctt
    88141 ctgaaacaat tggttgacat atctgtaccg tatagactgg ccaagtgtct cctcaaatct
    88201 tgagaagtgg ggtacatctg attagcagtc tctagcatac ttgcactcaa catgtgacct
    88261 gcaatcgtat caagggataa tggagcggta aaacgcacgg taattttgtg tgttttaaac
    88321 ttttttgatt ggataaaatg tgttgaaatt ccatgcacta actccatgat ttacctcctt
    88381 atatacagac ttctattata tcacgaaaac ctgaaatttt cttattccct gtaacacttt
    88441 tgaaataaaa atcgcttaca tttctctctg tctctctcac tatttttagg aaaatatggt
    88501 ataataccaa agattgaggt gaattatgga atacaaatta tttgaagaat ttattaccct
    88561 ccaagcacta ctcaaagaac ttggaattac acatagcgga ggagctatta aatcatttct
    88621 ctctgaacat tctgtttact ttaataggga attagagagt cgtcgtggaa aaaaacttcg
    88681 tattggcgat aaagttgaca tccctgacat gaacattgac atcttgttga cacaacctac
    88741 ttctgaagaa caagatgaat accaagctga taaagttgaa aaagaacgga tcgctaaact
    88801 tgtcaaaaag atgaataagg gagttaaaaa agacaaatcg aaacctgctt catcacctaa
    88861 aagccaacaa gctccacgat tccctggtag ataatcatgt ggctacaaca tctatctctc
    88921 aagacttttc gtaattacaa agaaacgaaa atagacttta atcctaaatt gaatgtcttt
    88981 ttgggacgta atgcacaagg aaaaacaaac atgttagagg ctatctattt tttagcctta
    89041 acgcgtagtc atcgaactcg aacagataaa aatctcattc attttgatga ggaacaactt
    89101 catctttcag gtctcgttca gaaaaaaact ggatccattc ccctagaaat cgaactaaca
    89161 caaaaaggcc gtgtaacaaa agttaatcac ttaaaacagg cacgcctttc agattatgta
    89221 ggacacatga atgttgtctt atttgctcct gaagatttac aactaattaa aggagcacct
    89281 tcgattcgac gaaaattcat tgatatggaa cttgggcaaa ttaagccaat ctacttatct
    89341 gacttaacca attataacca catcctaaag caaagaaaca cttacctaaa atcagatcaa
    89401 aaaatagatg aaacattcct ttctgtgtta gatgatcagc tagttgatta tggatgtcgt
    89461 gtaatgaatc accgcttaaa tttcataaaa aaactagaat catttgggcg taagaaacat
    89521 tttgaactct ctaatcagat cgaagagttg tcaatatcct atcaatcttc tgtcaatata
    89581 actgacaaac aaaacttatc cgaatctttc aaaattgctt tagaaaaaag taaatccaga
    89641 gatttattta aaaagaatac tggtgtcggt cctcatcgag atgacatttc tttttatata
    89701 aatgggatgg atgctagttt cggaagccaa ggtcaacatc gtagtctcgt cctctcgata
    89761 aaattagcag aaatcgaatt aatggaaagc attaccacag aatctccgat attactgctt
    89821 gacgatgtga tgagtgaact tgacaacact agacagttaa aattattaga aacgatttct
    89881 caatcaatcc aaacctttat cacaacaaca agcttagacc atcttcaaaa tctgccagaa
    89941 aatctaagta tcttcactat tcaggatggt aaagctgctg taaatggaaa ttgacaacat
    90001 tataaaagaa ctcctgtttt cactggagtt cttttcattg ttttttacat agaataattt
    90061 ggtgcctcat tagtaatttg cacatcatga ggatggcttt ctttcaaacc agcaccagac
    90121 atttcaataa attgagcatt atcgtgtagt tctttaaggt tagctgcacc acagtaaccc
    90181 ataccagagc gaataccacc aatcatttgg aaaacaatat cagctgccgc tcctttataa
    90241 gcaacacgac cttcaattcc ttctggaaca agcttgtttg cttcattgac agaaccttgg
    90301 aaataacggt cgcttgaacc tttcttcata gcagcaattg atcccatacc acggtaagtc
    90361 ttgaatttac gtccttggaa gatttcagtt tcgcctggag cttcatcagt tccagcaaac
    90421 atagatccaa gcataacagc atttccacct gcagcaagtg cttttacaat atctccagaa
    90481 tacttgatcc caccgtcagc aataatcgtt ttaccatatt cgcgcgcaac agctgcagca
    90541 tcgtagatag ctgttacttg cggaacacca acaccagcaa tcacacgagt agtacagata
    90601 gaacctggtc caataccaac cttaacaacg tctacacccg cttcataaag ggcacgtgca
    90661 ccttcagcag tagcaatatt tccagcaatc aaagtccgat ctgggaaatg agcacgaatc
    90721 tcggcaattt tacgcaagac acctgcagaa tgaccatgtg cagtatcaat aacaatcgca
    90781 tccgctcctg cctcaaaaag agcctctgca cgttcaaatg tatctgaagt aacacctact
    90841 gcacctgcaa ctagaagacg accaaactca tctttagccg catttggaaa ctcaataact
    90901 ttttcaatat ctttgatagt gatcaaacca gaaagactgc cttcttcatc gaccaacgga
    90961 agtttttcaa tacgatgctc ttgaagaata ctctcagccg ttgcaagatc cgtacccaca
    91021 ggagcagtaa caagattttc actagtcata tggtttgaaa ttggttgatt ataatctgaa
    91081 ataaaacgaa gatctcggtt tgtcaaaata ccaaccaatt tacgattttc aagtgtttca
    91141 acaactggaa caccactgat gcggtaacga cccataagct catctgcttc agcaattgta
    91201 tgttcaggcg tcaagaagaa cggatcaata ataactccat tttcagaacg ttttacctta
    91261 cgaacctcgt ctgcttgttg agcaattgac atgtttttat ggataactcc gagaccacct
    91321 gcacgagcaa tagcaatggc catttgactc tctgtaactg tgtccatggc agcggtaata
    91381 attgggatat ttaaagtcaa attatctgcc aatttagttg ttaaatctgc atcgttaggc
    91441 aacacatgac tttcagctgg aataagcaat acatcatcaa aggtaaaacc ttttttcaaa
    91501 aatttagtgt cccaattaga cattcgaagt ttcctctttt ctttcttttt gagcttgact
    91561 ctttttatat tgtatctatc ataccattct atacaaattt gtcaaatgtt acaggggtaa
    91621 ataaaaaact atcttttctt cgagatagaa atgatagttt cttgtaaaat aaacttagtt
    91681 aaagtaatga agtcccattg ccccttttac ctcagatagg gtttgacccg caacttcacg
    91741 cgctctttca ctaccttttt gaatcatatt ataaacttct cccatatcct tagcaaattc
    91801 aatacggcgc tcacgaatag gacccagttc acgttctaat atttcaagta gataacgctt
    91861 ggtcttcaca tcaccaagac cacctcgttg ataacgttct ttcatatcag caatttcttg
    91921 agcatcttct ggacgaccaa aaacatctag ataatggaaa accatatttc cctcaatctt
    91981 acctggatcc tcaacgcgga tatgatctgg atctgtatac atactcatta cttttttacg
    92041 caaagtatcc gcatcatcag ctaaataaat accattattt agtgatttag acattttagc
    92101 atttccatct aaaccaggca aacgccctgc tctctcattt tctggataaa taccttccgg
    92161 ctctaccaag acatcacagt tatatgcatt gttaaaagaa cgaacaattt cacgagtttg
    92221 ctcaatcatt ggtttctgat ctgtcccaac aggaacataa ttagccttga aagctgtgat
    92281 atcagctgct tgagcgattg gatagaccaa gaatcctgtc ggaatgcttt ctccaaatcc
    92341 tttctgagaa atctctgtct tgactgttgg atttcgctcc aaacgtgcta acgaaactag
    92401 attcatataa tacatagaca actcagccaa ctctggaatc tggctttgaa taaaaatagt
    92461 tgacttattt ggatccaatc caactgcaag ataatccaaa gccacatttc cgatagactc
    92521 tacaatggtt tgaggatctt tggcatgatc tgtcaaggct tgttggtcag ccaagaacac
    92581 aaacatatca tacttatcct cttcctgtaa taatactcga tttttgagac ttccaacata
    92641 atgtccaata tgcaattttc ctgttggacg gtctcctgtt aaaataatgg gtttagtcat
    92701 tttgttctcc ttcgatatag tcctttcaat tatagcattt ttttaatgaa ataaccgtaa
    92761 tttatcaaaa taaatcagcc ttgcttttta cagatttgtg taaaggatac tgtaaatata
    92821 atttacacaa aattgacaaa taaaaatttg aatatttctg tattttctag tagaataaat
    92881 atattacaca tataggagaa aaatattgct tacagtatct gatgtttcac tacgttttag
    92941 tgatcgcaaa ctttttgatg atgtcaatat caaatttaca gaaggaaata cttacggatt
    93001 aatcggtgct aatggtgccg gaaaatcaac ctttttaaaa attttagctg gagatatcga
    93061 acctactact ggtcacatct ctcttggtcc agatgaacgt ctctctgttc ttcgtcaaaa
    93121 tcactttgac tacgaagatg aacgtgccat tgatgtcgtt atcatgggaa atgaaaaact
    93181 ttatagcatc atgaaagaga aagatgctat ctacatgaag gaagatttct cagacgagga
    93241 cggggttcgt gctgccgaac tcgaaggaga gtttgccgaa cttggaggtt gggaagcaga
    93301 gagtgaagcc tctcaactac ttcaaaacct aaacattcca gaagaattac actaccaaaa
    93361 catgagcgaa ttggccaacg gtgaaaaagt aaaggttctc ctcgccaaag cactttttgg
    93421 taaaccagat gttcttctct tggacgagcc tactaacggt ttggatatcc aatcgattac
    93481 ttggttagaa gacttcttaa ttgactttga taacacagtt atcgtagtat cccacgaccg
    93541 tcacttctta aacaaagttt gtactcacat ggccgacctt gactttggaa aaatcaaact
    93601 ctatgtcgga aactacgact tctggaagga atcttctgag cttgctgcta aattgctagc
    93661 agaccgtaat gctaaagcag aagaaaaaat taaacaattg caagaattcg ttgctcgttt
    93721 ctctgccaat gcttctaagt caaggcaggc aacatcacgt aagaaaatgc ttgataagat
    93781 tgagctagaa gagattgtgc catctagtcg taaatatcca tttatcaact ttaaagcgga
    93841 acgtgagatt ggtaatgatc tcttgacagt agaaaatcta actgtaaaga ttgatggtga
    93901 aactatcttg gataatatta gtttcatctt gcgtccagat gataagacag cacttattgg
    93961 acaaaatgat attcaaacga ctgcattaat tcgtgcaatc atgggagata ttgactatga
    94021 aggaactgtc aagtggggag ttacaactag tcaatcttac ctaccaaaag ataactcagc
    94081 tgattttgca ggaggagaat caattcttga ctggttgcgt caattcgcaa gtaaagaaga
    94141 agatgacaat actttcctac gtggcttcct cggccgtatg ctcttctctg gagatgaagt
    94201 taacaaacct gtaaatgtct tgtcaggggg agaaaaagtt cgtgtcatgc tttcaaaact
    94261 catgctctta aaatcaaatg tccttgtact tgatgatcca acaaatcact tggacttgga
    94321 atctatctca agcttgaatg atggattgaa aaactttaaa gaatcaatca tctttgctag
    94381 ccatgaccac gaatttattc aaactttggc taaccatatc attgtcttat ctaaaaatgg
    94441 cgtcattgac cgtatcgatg aaacctacga tgaattccta gaaaatgcag aagtacaagc
    94501 aaaagttaaa gaactttgga aagactaaat aaaacttcaa aactcagttg ggttaaccaa
    94561 ctgagttttc tatcattcta cgaggtaaca tgaaatcatt tttaaaaaca tatcgaacct
    94621 attttatttc tttcatcatt cctgtagtga ttatgtctgg agtatatcta tctcaaggta
    94681 tctactggaa tagcgacaac tctcctctat taggagatgg ctttcatcaa tacgttattt
    94741 ttgatgtagc cttacgaaat atcctacatg gaaatagtag tctgttttac acctttacaa
    94801 gtggtctagg gctaaacttc tatgccctat ctagttatta cttgggtagt tttctcgcgc
    94861 ctctagttta cttttttgat ctaacgaata tgccagatgc tgtctatctg accactctct
    94921 taaaatttgg attgattggt ctgtcaacct tttttagttt gaataaattg tttcaatcta
    94981 tccctcagac tttaaaacta gccttatcta cttcctatgc tctgatgagt ttcactgtca
    95041 gtcaattaga gataaaaacc tggctagatg tttttatctt gattccttta attataactg
    95101 gtttacatct actgataact gaaaagaaac tcctattgta ctttacaagt ctgtcaatct
    95161 tatttattca aaattattat tttggatata tgacagtatt gtttcttatt ttctggtatc
    95221 tctgtcaaat ttcgtgggac tttaagactc gaaaatcatc tgttcttgat ttcatagtta
    95281 tctccttttt agctggtatg gctagtttga ttatgactct tcccactcta tttgatttac
    95341 agacacatgg ggaaaaattg actgaagtta caaagtttca aactgaaagt agctggtatc
    95401 ttgatctctt tgctaagcaa ttcattggtt cctttgacac aacaaagtat ggggccatcc
    95461 caatgatttt tgttggacta tttcccttta ttttgaccat tttatttttt acgctgaaat
    95521 ctattaagtt tcacgtgaaa ctcatatatg taatattctt tgcatttcta attgcaagct
    95581 tttacataga agctcttgac ttattttggc aaggcatgca tactccaaac atgtttttac
    95641 atcgctatgc ttggattttc tctaccttgt taatttacac agcagcagaa gtcttaaagc
    95701 gtctgaaaga acttaaagtc tggaattttt tagtttcgct ttttcttgta gtagcaggat
    95761 ttttagctac catctatcta aaatcgcatt attctttttt aacagatttg aatattctgc
    95821 ttactcttga atttttggtt gtctattctc ttttactcct tgcagttatc aaaaagttta
    95881 tatctgtgaa tctatttgcc attctaatct ctttatttat actggttgaa atgagtttaa
    95941 atgcttcatc tcaaatggac ggaattgcta aggaatgggg atttgcttct cgaagtgctt
    96001 atagtcgaga tatcccagct atggaatctt tctcaacata tattggaaat caatttactc
    96061 gtactgaaaa actacaaact cagacaggaa atgacagtat gaaattcaac tacaatggaa
    96121 tctctcaatt ttcatctgtt cgaaatcgtt catcaagctc tactttagat aaacttggtt
    96181 ttaaatcctc tgggactaat ctcaatctcc gatatgcaaa taatagtatt ttggctgata
    96241 gtttatttgg tatccagtac aatatctcag acagtcctat tgataagtat ggctttaaag
    96301 atatctatca aaaagataat cttaccctat atgaaaatca atactctctt ccgattgcag
    96361 ttgctagtca atctgtttac aatgatgtca agttcaatga acataccttg gataatcagg
    96421 cctcattttt aaatcaactt gctaacgtca attttgatta tttttctcca ataccttatg
    96481 aaaaaacaga aaaaatagaa aatactaatg atttgattag tgtcacaagt tcttcaaatg
    96541 aagatgcagc aatccagtat caaattgaag ttccagaaaa cagccaagtt tatctctctt
    96601 tcataaacct tcacttttct aacgataaac aaaagaaggt tgacatactt gtaaatggtg
    96661 aaaaaaagac ttttacaact gataatgtct tctccttctt taatctagga tatactaaag
    96721 agaaaaaaac tttcaatatc aatgttagtt tccctggaaa ttcacaagta tcatttgaat
    96781 ctcctacctt ctatcgttta gataccaaaa ctttcaccga ggcaattcaa aaaattaaag
    96841 aacaacctgt cacagtatca acttctaaaa acaaggtttt tgctacatat gatgtccaac
    96901 aagatacatc tattttcttc accattcctt atgacaaagg ttggtctgcc taccaagatg
    96961 gtaagaaaat agaaattaaa caagctcaaa ctggatttat gaaagttgac attcccaagg
    97021 ggaaaggaac tattacactt tccttcattc ccaatggttt tattactgga gcaatctgtt
    97081 cctttacttc tctcttacta tttggaatct ataatcacag acgaaagtca tctaaggcat
    97141 aaaaaatcga ccagttaatc ggtcgatttt tttaatcttc ttccattttc ttatgttgat
    97201 aggctagcat acctaaacca gtaaatagag ctagtatgac agctaggaaa atgacttgtt
    97261 gatagagatt gtttgtcgta atcccgaaac tgaatagctc attggtaacc agggattaat
    97321 agatctaaag aaatcatttg tcaaagcaag tggataagta cctgcacttg atgctaactg
    97381 tagtaaaagc aaaataagtg agaaaaaagc tcctatacgg ctattccacg ttgctaaagt
    97441 ggtcaccata gacatgaata ctaaacttgt taggatgatg agaataaata ttctcatctc
    97501 atgattagca gttaaaccaa taagctgaac tcctccatat accaaaattc ctgccaaaac
    97561 agctataata ccatttattt cagctcaaga tttcaaccaa gcccaacggc tctctggatg
    97621 acgtcctgaa ggcaatttcg caaatatcat atttgttgat attgctgcaa aaaaaagagc
    97681 aactgatatc atataaggag ctattgcgat tccatttaca ggaacttgat cattgtctgt
    97741 ttttgaaaga ttgagtggat ttgacaaaat ctctgcattt ttagattctg ttgatactga
    97801 tttgagttga tcactagcat tacctagtcc ttgtcctaaa gaagcaagtc ctgtctgtaa
    97861 atcttccaat ccagaagtta actttgttcc accttctgct agtttcccag atccatctgc
    97921 caatttatta gctctattct ctaatggaga agcacctgaa agtaactgac tggatttgtc
    97981 tgctaattgc ccagatcctg attgtaatta accaactcct gctgtcaatc tagaagattt
    98041 ttgtgtcaag gtgtttgagc ctgaaactag tttatccaaa ctacctgtca aggtggcatt
    98101 tttttcactt agttgacttg cgccctgaga aactttatca acacctgtag tatatgcgtt
    98161 tacacctgat gcaatcaact gactggcagg aactaatttg ctagtaacag ctccttgtat
    98221 ctctgttaat ccacttgaca atcctatcaa agaagtagaa gtaataggta atacttgatt
    98281 agcttgattt tttaaagtcg aaagattaga agattgattt tgtaagtttt ctaaacttcc
    98341 ctgtaaacct tgtactaaag ctacaattga ctgagccgat tgaatactat cagttgaatt
    98401 ttgagataca gaatcactta tcccagtttg ttgctcactt gtcaatgatt gataagctgc
    98461 tgtcgattga atattggata atgtagttgt ttttttagat aaatcacttg gtaaagtcac
    98521 taccatatag taatcgccat cttccaatcc cttctttcct tcctcttcat ctacaaaatg
    98581 aaaatccaag gttttatttt cttttaaatt ggacaccatg tcttttccta ttgccatagt
    98641 attaccatta taggaagcct ctttatcatt atttacaact gccacaggta agtcagacaa
    98701 ttgcccatat ggatcccaca ttgatgacaa aaatatgata ttgtacagag ctggaataag
    98761 agaaatcccg atcatgacaa taataaaggt tgtttttttt aaattgcttt ccattcttta
    98821 aacatagttt ctcctttttt aaacatattg tctaaaattt tgatataata gattatacat
    98881 taaaaaatct aaattacaag ataaaaaatc tatttttaga catatagtct aatttgttta
    98941 caaggaggaa atatgcaaga aagtaacaaa cgcttaaaaa caaagcgaac tattgaaaat
    99001 gctatggtac aattactgat ggaacagcca tttgataaaa tttctactgt caaattagta
    99061 gaaaaagccg gaattagtcg ttccagcttc tatactcact ataaggataa gtatgatatg
    99121 attgagcact atcaaagcaa gctattccat acatttgaat atatttttca aaaacatgct
    99181 catcacaaaa gagacgctat tttagaagtt tttgaatatc tagagtcaga accacttctg
    99241 gctgcccttc tttctgaaaa tgggactaaa gaaatccaaa atttcttacg aaataaactt
    99301 catatcatgc ttagtacaga tttacaaaag cgatttatgc aactgaatct aaataccact
    99361 gaattagaat atagtagcat ctatctaact catgcacttt ttggtgtctg ccaaacttgg
    99421 attgcacatg gaaaaaaaga aagttctcaa gaaataacag acttccttat gaaaatgctt
    99481 ggtgatacaa attgatacaa aaagaggaac acagctgtgt tcccttttat ctatactccg
    99541 ccagtaggac tcgaacctac gacatcatga ttaacagtca tgcgctacta ccaactgagc
    99601 tatggcggat aaaatagtcc gtacgggatt cgaacccgtg ttaccgccgt gaaaaggcgg
    99661 tgtcttaacc ccttgaccaa cggaccttct atctgtagca gatataacca ttatatcaat
    99721 ttcttgctaa ttgtcaatca cttttgagat tttttctcta aaatatcttt taattttcta
    99781 atttttaatc ttgaaatagg acaacgatgg tcttcataga aaacaatttc taagtttttt
    99841 cgatcaattt ctctgatatt gcctatattt accaaaaatg acttgtgagg agaataaaat
    99901 cgctgagtat gtttgtcctt ttcctgaata tctgtcatgg taccataaaa ctcttttgca
    99961 aaattcttac caataatgcg caatttatga gatacccctg ttgtttcaat atacaaaata
   100021 tcatggtaag gaatttttaa atcatttccc ttgtaattgt agtcgaaata atctacaaca
   100081 tcttcatttt caagtaacat actcttcgtg tagaagatat tttgctcaat tctcttctta
   100141 aacatctcat cattgatatc cttatcaaca aaatctaggg ctgatacctg gtatttatag
   100201 gttagagtcg caaactctga tcgactagtg ataaagacga taatagcgta aggattgtaa
   100261 tgacgaatga gctgagccac ttcaaatccc tttttctcaa ttccatgaat atcgatatct
   100321 aggaaataaa gctgatttac ttcatcattt tcaatgtatt cttcaaattc acggactttt
   100381 cccgttgtct tgtatgatat tggaatattc gattctttcg aaatttcatc caatattctc
   100441 tctagtctca cttgatgttc aataacatct tctaaaatta aaactttcat tcaaattccc
   100501 tcttaaatct aatgatttgt ctaaatgtac tgccttccat ctctgtttct aaaataatat
   100561 tgttgtactt atctagtagt tctttcacat tatttaatcc gactccgcga tttcttccct
   100621 tagtggagaa tcctaaggca aatagatctc ctgaaggagt catcgtcatt ttacatgaat
   100681 tctgaatcac aataactgtt tcagtttcca tcttaataac tgctacttcc atctgctttt
   100741 tatagctatc agccgatcct tcgacagcat tattcaataa aacgctcatg atacgaacca
   100801 aatccaatag ttcaattgga agcttggtaa tcgtatcttt tacttccagt gtaaactcta
   100861 caccattatt tcgagcatag acaattgact gagcaaccaa acttcgtaaa gctgagtctt
   100921 ctatgttgtt caaatcaaag taagtgtact tatctgaacg caatttatga tttgctttga
   100981 ctaaaacttc attgtaaatt ctgtcaattt cctgtaaatt accactgtca attgccatct
   101041 gcatgctgac aagcattcca gcataatcat gtcgaaaacc acggatttca ttatacagac
   101101 caacaatttc atctgtgtaa ttctgtaaat gtttctgttc aaatttcttc tgcttcaaag
   101161 caatctcttt ctccatttga actttatgag aattcattgc aaagaaggtc aaaaggagag
   101221 agataaagac aatagatgac aaaatacttc caaaactatt caaatgttta atcgtactta
   101281 ccatatctga aacgaaagat acaatatgta gcaatagtaa agcaaaaaat acttttttca
   101341 agaaaggata aaggtagtcc tcgtcaaaat aggctagttc caaatggaaa tagtaaatga
   101401 tttttaatgt aacaaaatag gttaacaccg tcacaacgaa aaagaatggg aaatgatatt
   101461 gtaaaacaaa attatctcct gttatagagg agaaagttac ggacagaaag ttatgagtgc
   101521 tctcatataa aagagatagt agtaaactta ggaatagtcc tctatccctc tcatactgtt
   101581 tcatccatcg aaaataggaa tataatccca aaggaaataa aaatctttca atccctaacc
   101641 catctaaata tagaatatat aagggaaaat caaatactat ttctgttagt aatgtataag
   101701 caccaaaaac gaataattct tttctattta tttgaccttt acaaataaaa tggtaactgt
   101761 gactaataat taaaaaatga acaataaccg tcccaaatcc aaataaatcc attactcttt
   101821 ccccttattt cattactttt ttctttgtaa aataaaatca cggaagaatt ttgacaacct
   101881 catctcccca cctttaatct tttgtaagtc tttttccttc aaagctacaa actgttccaa
   101941 tttaactgtg tttttcataa taaaatctcc taaaatgttt tttcttgtaa gctaacttac
   102001 aaaaaccatt atacaaaatg gaatttcgtt ttagataaaa ttctctcaac tgtcattttt
   102061 ttctcccaaa gtgtactttt ttaagaaaaa agccgggaaa attcccagct ttgctattat
   102121 attgatccca gcaggattcg aacctgcgac cgttcgctta gaaggcgaat gctctatcca
   102181 gctgagctat gagacctaat acaattattc taccaaaaat tcaattaaaa gtcaattttc
   102241 tatttatggt aggggaatcc ctgctgaatc gtaaaagcgc gatagatttg ttcaacaaga
   102301 actagtctca ttaactgatg gggtaaggtt aggcgaccaa aactgacaga aagattggct
   102361 ctatttttta cagatgatga caatcctaaa cttcccccaa taataaaagt aagagtagaa
   102421 aatcctttta tagaagtttc ttctaactgc ttactaaatt cttctgagaa gaaagttttc
   102481 ccttcaatgg ctaacacaat aacgaaatca cggtcagcaa tttttgataa aattctctga
   102541 ccttctattt ctaaaatctt ttgattttct gattcactgg ccttatctgg tgttttttca
   102601 tctgataact caatcatttc aaacttagca aatctagaaa ttcgttttga atactctgcg
   102661 ataccatctt ttaaatactt ttctttcagt ttcccaactg ttacaacttt aattttcatg
   102721 actctattct aacatattct ctattttttc acatcttatt cacaaaataa aaaatagatt
   102781 tcaattaaga aaatcacagt ttcaaaagag ttatccacag tttgtgtaaa acttttgtgt
   102841 ttaagttata attaagctag tcagtttata ctttcagtaa ttcaaacata tggaggcaaa
   102901 tatgaaacat ctaaaaacat tttacaaaaa atggtttcaa ttattagtcg ttatcgtcat
   102961 tagctttttt agtggagcct tgggtagttt ttcaataact caactaactc aaaaaagtag
   103021 tgtaaacaac tctaacaaca atagtactat tacacaaact gcctataaga acgaaaattc
   103081 aacaacacag gctgttaaca aagtaaaaga tgctgttgtt tctgttatta cttattcggc
   103141 aaacagacaa aatagcgtat ttggcaatga tgatactgac acagattctc agcgaatctc
   103201 tagtgaagga tctggagtta tttataaaaa gaatgataaa gaagcttaca tcgtcaccaa
   103261 caatcacgtt ataaatggcg ccagcaaagt agatattaga ttgtcagatg ggactaaagt
   103321 acctggagaa attgtcggag ctgacacttt ctctgatatt gctgtcgtca aaatctcttc
   103381 agaaaaagtg acaacagtag ctgagtttgg tgattctagt aagttaactg taggagaaac
   103441 tgctattgcc atcggtagcc cgttaggttc tgaatatgca aatactgtca ctcaaggtat
   103501 cgtatccagt ctcaatagaa atgtatcctt aagatcggaa gatggacaag ctatttctac
   103561 aaaagccatc caaactgata ctgctattaa cccaggtaac tctggcggcc cactgatcaa
   103621 tattcaaggg caggttatcg gaattacctc aagtaaaatt gctacaaatg gaggaacatc
   103681 tgtagaaggt cttggtttcg caattcctgc aaatgatgct atcaatatta ttgaacagtt
   103741 agaaaaaaac ggaaaagtga cgcgtccagc tttgggaatc cagatggtta atttatctaa
   103801 tgtgagtaca agcgacatca gaagactcaa tattccaagt aatgttacat ctggtgtagt
   103861 tgttcgttcg gtacaaagta atatgcctgc caatggtcac cttgaaaaat acgatgtaat
   103921 tacaaaagta gatgacaaag agattgcttc atcaacagac ttacaaagtg ctctttacaa
   103981 ccattctatc ggagacacca ttaagataac ctactatcgt aacgggaaag aagaaactac
   104041 ctctatcaaa cttaacaaga gttcaggtga tttagaatct tgattgacat ctatgtaaag
   104101 aaagctttac ataagagaaa agatgtgtta gtgtagaatc atggaaaaat ttgaaatgat
   104161 ttctatcaca gatatacaaa aaaatcccta tcaaccccga aaagaatttg atagagaaaa
   104221 actagatgaa ctagcacagt ctatcaaaga aaatggggtc attcaaccga ttattgttcg
   104281 tcaatctcct gttattggtt atgaaatcct tgcaggagag agacgctatc gggcttcact
   104341 tttagctggt ctacggtcta tcccagctgt tgttaaacag atttcagacc aagagatgat
   104401 ggtccagtcc attattgaaa atttacagag agaaaattta aacccaatag aagaagcacg
   104461 cgcctatgaa tctctcgtag agaaaggatt cacccatgct gaaattgcag ataagatggg
   104521 caagtctcgt ccatatatca gcaactccat tcgtttactt tccttgccag aacagattct
   104581 ttcagaagta gaaaatggca aactatcaca agcccatgcg cgttccctag ttgggttaaa
   104641 taaggaacaa caagactatt tctttcaacg gattatagaa gaagatattt ctgtaaggaa
   104701 attagaagct cttctgacag agaaaaaaca aaagaaacag caaaaaacta atcatttcat
   104761 acaaaatgaa gaaaaacagt taagaaaact actcggatta gatgtagaaa ttaaactatc
   104821 taaaaaagac agtggaaaaa tcattatttc tttttcaaat caagaagaat atagtagaat
   104881 tatcaacagc ctgaaataag gctgttcttt tattttttta tctcacaagg ttatccacta
   104941 tgtttttcga taaaaagctt aataaatcaa taatttcttc ttttatcccc aacctgtgga
   105001 taaagtttgg taacattgtg gattattttt cacagcttgt ggaaaattct tgctatctat
   105061 ggtaaaatat ctctagtatt aaacttttaa atagtaaagg aggagaaagg attgaaagaa
   105121 aaacaatttt ggaatcgtat attagaattt gcacaagaaa gactgactcg atccatgtat
   105181 gatttctatg ctattcaagc tgaactcatc aaggtagagg aaaatgttgc cactatattt
   105241 ctacctcgct ctgaaatgga aatggtctgg gaaaaacaac taaaagatat tattgtagta
   105301 gctggttttg aaatttatga cgctgaaata actccccact atattttcac caaacctcaa
   105361 gatacgacta gctcacaagt tgaagaagct acaaatttaa ctctttataa ctatagtcca
   105421 aagttagtat ctattcctta ttcagatacg ggattaaaag aaaagtatac ctttgataac
   105481 tttattcaag gggatggaaa tgtttgggct gtatcagccg ctttagctgt ctctgaagat
   105541 ttggctctga cctataaccc tctttttatc tatggaggac caggccttgg taagactcac
   105601 ttattaaacg ctattggaaa tgaaattcta aaaaatattc ctaatgcgcg tgttaaatat
   105661 atccctgccg aaagctttat taatgacttt cttgatcacc taagacttgg ggaaatggaa
   105721 aagtttaaaa agacctatcg tagtcttgat cttttgttaa tcgatgatat tcagtcactc
   105781 agcggaaaaa aagttgcaac tcaggaagaa tttttcaata cctttaacgc ccttcatgac
   105841 aagcaaaaac agattgtcct aacgagtgat cgtagtccaa aacatctaga agggctcgag
   105901 gagaggcttg tcacgcgttt tagttgggga ttgacacaaa ctatcacacc ccctgacttt
   105961 gaaacacgta ttgccatttt acaaagtaaa acggaacatt taggctacaa tttccaaagt
   106021 gatactctag aatacctagc tgggcaattt gattcaaatg ttcgagatct tgagggagcc
   106081 atcaacgaca tcactttaat tgccagagta aaaaaaatca aggatatcac tattgatatt
   106141 gctgcagaag ccattagagc ccgcaaacaa gatgttagcc aaatgctcgt catcccaatt
   106201 gataaaatcc aaactgaagt tggtaacttt tatggtgtta gtatcaaaga aatgaaggga
   106261 agtagacgcc ttcaaaatat tgttttggcc cgtcaagtag ccatgtattt atctagagaa
   106321 ctaacagata atagtcttcc aaaaattggg aaggaatttg ggggaaaaga tcataccaca
   106381 gtcattcatg cccatgccaa aataaaatct ttgattgatc aagacgataa tttacgttta
   106441 gaaattgaat caatcaaaaa gaaaatcaaa taatttgtgg ataactttta gttttttatc
   106501 ttttttatcc acatttttta aacaagctaa aaaacttgat atgacttgtt taaaggctgt
   106561 tttccacaga tttcacagac tctattatta ctattatctt tctaatacta aaaataaata
   106621 aaggagaatc catgattcat ttttcaatta ataaaaattt atttctacaa gcattaaata
   106681 ctactaagag agctattagt tctaaaaatg ccattcctat tttatcaaca gtaaaaattg
   106741 acgtgaccaa tgaaggtatt actttaattg gttcaaatgg tcaaatttca attgaaaatt
   106801 ttatttctca aaaaaatgaa gatgctggtt tgttaattac ttctttaggt tcgatccttc
   106861 ttgaagcttc tttctttatc aatgtagtat ctagtttacc tgatgtaact cttgatttta
   106921 aagaaattga acaaaatcaa attgttttaa ccagtggcaa atcagaaatt accctaaaag
   106981 gaaaagatag cgaacaatat ccacgaatcc aagaaatttc agcaagcact cctttaatac
   107041 ttgaaacaaa attactcaag aaaattatta atgaaacagc ctttgctgca agtacacaag
   107101 agagtcgtcc gattttaaca ggtgtccact tcgtattgag tcaacacaaa gagttaaaaa
   107161 cagttgcaac agactctcat cgcctaagcc agaaaaaatt gactcttgaa aaaaatagtg
   107221 atgattttga tgtcgtaatt cctagccgtt ctctacgcga attttcagcg gtatttacag
   107281 atgatatcga aactgtagag attttctttg ccaataacca aatcctcttt agaagcgaaa
   107341 atattagctt ctatactcgt ctcctagaag gaaactatcc tgatacagat cgcttgattc
   107401 caacagactt taacactact attactttta atgtggtaaa cttacgccag tcaatggagc
   107461 gtgcccgtct tttatcaagt gcgactcaaa atggtactgt gaaacttgaa attaaggatg
   107521 gggttgttag cgcccatgtt cactctccag aagttggtaa agtaaacgaa gaaatcgata
   107581 ctgatcaggt tactggtgaa gatttgacca ttagtttcaa cccaacttac ttgattgatt
   107641 ctcttaaagc tttaaatagc gaaaaggtga ccattagctt tatctcagct gttcgtccat
   107701 ttactcttgt gccagcagat actgacgaag acttcatgca gctaattaca ccagttcgta
   107761 caaattaagt gaaagaggtt gagcctggct cgcctctttt atgatataat cgaaaaagaa
   107821 aaggagagta gtatgtatca agttggaaat tttgttgaga tgaaaaaatc acacgcttgt
   107881 acaatcaagt caactggtaa aaaggctaat cgttgggaaa ttacacgtgt aggagcagat
   107941 atcaaaataa aatgcagtaa ttgtgagcat gttgtcatga tggggcgata tgattttgag
   108001 cgaaaaatga ataaaattat tgactgagaa cccttagtta gagggttagc actttatccc
   108061 tttttgtgtt ataatattag ggattgaaat gaaaacggag aatgagaaat atggctttga
   108121 cagcaggtat cgttggtttg ccaaacgttg gtaaatcaac actatttaat gcaattacaa
   108181 aagcaggagc agaggcagca aactacccat ttgcgactat tgatccaaat gttggaatgg
   108241 tggaagttcc agatgaacgc ctacaaaaac taactgaaat gataactcct aaaaagacag
   108301 ttcccacaac atttgaattt acggatattg cagggattgt aaaaggagct tcaaaaggag
   108361 aagggctagg gaataaattc ttggccaata ttcgtgaagt agatgcgatt gttcacgtag
   108421 ttcgtgcttt tgatgatgaa aatgtgatgc gcgagcaagg acgtgaagac gcctttgtag
   108481 atccacttgc agatattgat acaattaatc tggaattaat tcttgctgac ttagaatcag
   108541 tgaacaaacg atatgcgcgt gtagaaaaga tggcacgtac gcaaaaagat aaagaatcag
   108601 tagcagaatt caatgttctt caaaagatta aaccagtcct agaagacggg aaatcagctc
   108661 gtaccattga atttacagat gaggaacaaa aggttgtcaa aggtcttttc cttttgacga
   108721 ctaaaccagt tctttatgta gctaatgtgg acgaggatgt ggtttcagaa cctgactcta
   108781 tcgactatgt caaacaaatt cgtgaatttg cagcgacaga aaatgctgaa gtagtcgtta
   108841 tttctgcgcg tgctgaggaa gaaatttctg aattggatga tgaagataaa aaagagtttc
   108901 ttgaagccat tggtttgaca gaatcaggtg tagataagtt gacgcgtgca tcttaccact
   108961 tgcttggatt gggaacttac ttcacagctg gtgaaaaaga agttcgcgct tggactttca
   109021 aacgtggtat gaaggctact caagcagctg gtattatcca ctcagacttt gaaaaaggct
   109081 ttattcgtgc agtaaccatg tcatatgaag atctagtgaa atacggatct gaaaaggccg
   109141 taaaagaagc tggacgcttg cgtgaagaag gaaaagaata tatcgttcaa gatggcgata
   109201 tcatggaatt ccgctttaat gtctaaaaat taataaatgg tgtcaattag gttggaaaaa
   109261 aattccaacc cttttggctt ttgaaaggaa aaataaatga ccaaattact tgtaggcttg
   109321 ggaaatccag gggataaata ttttgaaaca aaacacaatg ttggttttat gttgattgat
   109381 caactagcga agaaacagaa tgtcactttt acacacgata agatatttca agctgaccta
   109441 gcatcctttt tcctaaatgg agaaaaaatt tatctggtta aaccaacgac ctttatgaat
   109501 gaaagtggaa aagcagttca tgctttatta acttactatg gtttggatat tgacgattta
   109561 cttatcattt acgatgatct tgacatggaa gttgggaaaa ttcgtttaag agcaaaaggc
   109621 tcagcaggtg gtcataatgg tatcaagtct attattcaac atataggaac tcaggtcttt
   109681 aaccgtgtta agattggaat tggaagacct aaaaatggta tgtcagttgt tcatcatgtt
   109741 ttgagtaagt ttgacaggga tgattatatc ggtattttac agtctgttga caaagttgac
   109801 gattctgtaa actactattt acaagagaaa aattttgaga aaacaatgca gaggtataac
   109861 ggataaatgg tgaccttatt agatttattc tcagaaaatg atcagattaa aaaatggcat
   109921 caaaatttaa cagataagaa aagacaacta atacttggtt tatcaacatc tactaaggcg
   109981 cttgcaattg caagcagttt agaaaaagaa gataggattg tgttattgac gtcaacttat
   110041 ggagaagcag aaggacttgt tagtgatctt atatctatct tgggtgagga actcgtctat
   110101 ccatttttgg tagatgatgc tcctatggtg gagtttttga tgtcttcaca ggaaaaaatt
   110161 atttcacggg ttgaagcctt gcgttttttg actgattcat ctaagaaagg gattttagtt
   110221 tgtaatatcg cagcaagtcg attgatttta ccgtctccca atgcattcaa agatagtatt
   110281 gtaaaaatct cagttggtga agaatatgat caacacgcgt ttatccatca gttaaaggaa
   110341 aatggctatc gaaaagttac tcaagtacaa actcagggcg aatttagtct tcgaggagat
   110401 attttagata tttttgaaat atcccagtta gaaccttgtc gaattgagtt ttttggtgat
   110461 gaaattgatg gtatcaggtc atttgaagta gaaacacaat tatcgaaaga aaataagaca
   110521 gaactcacta tctttccagc tagtgatatg cttttgagag aaaaggatta tcaacgagga
   110581 cagtcagctt tagaaaaaca aatttcaaaa actttatcac ctattttgaa atcataccta
   110641 gaagaaattc tttcaagttt tcatcaaaag caaagtcatg cagattctcg gaagttttta
   110701 tctttgtgct atgataagac atggactgtc tttgattata ttgaaaaaga tactccaata
   110761 ttctttgatg attatcaaaa attgatgaat cagtatgaag tatttgaaag agaattagcg
   110821 cagtacttta cagaagaatt acagaatagt aaagcatttt ctgatatgca gtatttttct
   110881 gatattgaac aaatctataa aaaacaaagt ccagtgacct ttttctctaa tcttcaaaag
   110941 ggtttaggaa atctcaaatt tgacaaaatt tatcaattca atcaatatcc tatgcaggaa
   111001 tttttcaatc agttttcttt tctaaaagaa gaaattgaac gatataaaaa aatggattac
   111061 accattattc tgcagtctag caattcaatg ggaagtaaaa cattggagga tatgttagag
   111121 gaatatcaga ttaaattgga ttctagagat aagacaagta tctgtaaaga atctgtaaac
   111181 ttaatagagg gtaatctcag acatggtttt cattttgtag atgaaaagat tttattgata
   111241 actgaacatg agatttttca aaagaaatta aagcgtcgtt ttcgaagaca acatgtttca
   111301 aatgcagaga gattaaaaga ttacaatgaa cttgaaaaag gggactatgt tgtccatcat
   111361 atccatggga ttggtcaata tctaggaatt gaaaccattg aaatcaaggg aattcatcgc
   111421 gattatgtca gtgtccaata ccaaaatggt gatcaaattt ctattcccgt ggaacagatt
   111481 catctactgt ccaaatatat ttcaagtgat ggtaaagttc caaaactcaa taaattaaat
   111541 gatggtcatt ttaaaaaggc caagcaaaag gttaagaacc aggtagagga tatagctgat
   111601 gatttaatca aactctactc tgaacgtagt cagttgaagg gttttgcttt ctcagctgat
   111661 gatgatgatc aagatgcctt tgatgatgct ttcccttatg ttgaaacgga tgatcaactt
   111721 cgtagtattg aggaaatcaa gagggatatg caggcttctc acccaatgga tcgactttta
   111781 gttggggatg ttggttttgg aaagactgaa gttgctatgc gtgcagcctt taaagcagtc
   111841 aatgatcaca aacaggttgt cattctagtt ccgacgacgg ttttagcgca acagcactat
   111901 acgaatttta aggaacgatt ccaaaatttt gcagttaatg ttgatgtgtt gagtcgcttt
   111961 agaagtaaaa aagagcagac tgcaacactt gaaaaattga aaaacggtca agtcgatatt
   112021 ttgattggaa cacatcgtgt tttgtcaaaa gatgttgtgt ttgctgattt gggcttgatg
   112081 attattgatg aggaacagcg atttggtgtc aagcataagg aaactttgaa agaactgaag
   112141 aaacaagtgg atgtcctaac cttgaccgct acgccaatcc ctcgtaccct ccatatgtct
   112201 atgctgggaa tcagagattt gtctgttatt gaaactccgc cgactaatcg ctatcctgtt
   112261 cagacctatg ttttggaaaa gaatgatagt gtcattcgtg atgctgtctt gcgtgaaatg
   112321 gagcgtggag gtcaagttta ctatctttac aacaaagttg acacaattgt tcagaaggtt
   112381 tcagaattac aggagttgat tccggaggct tcgattggat atgttcatgg tcgaatgagt
   112441 gaagtccagt tggaaaatac tctattagac tttattgagg gacaatacga tatcttggtg
   112501 acgactacta ttattgagac aggggtggac attccaaatg ctaatacttt atttattgaa
   112561 aatgcggacc atatgggctt gtcaacctta tatcagttaa gaggaagagt cggtcgtagt
   112621 aatcgtattg cttatgctta tctcatgtat cgtccagaaa aatcaatcag tgaagtctct
   112681 gaaaagagat tagaagcgat taaaggattt acagaattgg gctctggctt taagattgca
   112741 atgcgagatc tttcgattcg tggagcagga aatcttttag gaaaatccca gtctggtttc
   112801 attgattctg ttggttttga attgtattcg cagttattag aggaagctat tgctaaacga
   112861 aacggtaatg ctaacgctaa cacaagaacc aaagggaatg ctgagttgat tttgcaaatt
   112921 gatgcctatc ttcctgatac ttatatttct gatcaacgac ataagattga aatttacaag
   112981 aaaattcgtc aaattgacaa ccgtgtcaat tatgaagagt tacaagagga gttgatagac
   113041 cgttttggag aatacccaga tgtagtagcc tatctgttag agattggttt ggtcaaatca
   113101 tgcttggaca aggtctttgt tcaacgtgtg gaaagaaaag ataataaaat tacaattcaa
   113161 tttgaaaaag tcactcaacg actgttttta gctcaagatt attttaaagc tttatccgta
   113221 acgaacttaa aagcaggcat cgttgagaat aagggattaa tggagcttgt atttgatgtc
   113281 caaaataaga aagattatga aattttagaa ggtttgctga tttttggaga aagtttatta
   113341 gagataaaag agtctaagga agaaaattcc atttgatatt tttcttctat aaaatagata
   113401 aaaatggtac aataataaat tgaggtaata aggatgagat tagataaata tttaaaagta
   113461 tcgcgaatta tcaagcgtcg tacagtcgca aaggaagtag cagataaagg tagaatcaag
   113521 gttaatggaa tcttggccaa aagttcaacg gacttgaaag ttaatgacca agttgaaatt
   113581 cgctttggca ataagttgct gcttgtaaaa gtactagaga tgaaagatag tacaaaaaaa
   113641 gaagatgcag caggcatgta tgaaattatc agtgaaacac gggtagaaga aaatgtctaa
   113701 aaatattgta caattgaata attcttttat tcaaaatgaa taccaacgtc gtcgctacct
   113761 gatgaaagaa cgacaaaaac ggaatcgttt tatggggggg gtattgattt tgattatgct
   113821 attatttatc ttgccaactt ttaatttagc gcagagttat cagcaattac tccaaagacg
   113881 tcagcaatta gcagacttgc aaactcagta tcaaactttg agtgatgaaa aggataagga
   113941 aacagcattt gctaccaagt tgaaagatga agattatgct gctaaatata cacgagcgaa
   114001 gtactattat tctaagtcga gggaaaaagt ttatacgatt cctgacttgc ttcaaaggtg
   114061 ataaaatgga aaatttatta gacgtaatag agcaattttt gagtttgtca gatgaaaagc
   114121 tggaagaatt ggctgataaa aatcaattat tgcgtttaca agaagaaaag gaaaggaaga
   114181 atgcgtaaat tcttaattat tttgttgcta ccaagttttt tgaccatttc aaaagtcgtt
   114241 agcacagaaa aagaagtcgt ctatacttcg aaagaaattt attacctttc acaatctgac
   114301 tttggtattt attttagaga aaaattaagt tctcccatgg tttatggaga ggttcctgtt
   114361 tatgcgaatg aagatttagt agtggaatct gggaaattga ctcccaaaat aagttttcaa
   114421 ataaccgagt ggcgcttaaa taaacaagga attccagtat ttaagctatc aaatcatcaa
   114481 tttatagctg cggacaaacg atttttatat gatcaatcag aggtaactcc aacaataaaa
   114541 aaagtatggt tagaatctga ctttaaactg tacaatagtc cttatgattt aaaagaagtg
   114601 aaatcatcct tatcagctta ttcgcaagta tcaatcgaca agaccatgtt tgtagaagga
   114661 agagaatttc tacatattga tcaggctgga tgggtagcta aagaatcaac ttctgaagaa
   114721 gataatcgga tgagtaaagt tcaagaaatg ttatctgaaa aatatcagaa agattctttc
   114781 tctatttatg ttaagcaact gactactgga aaagaagctg gtatcaatca agatgaaaag
   114841 atgtatgcag ccagcgtttt gaaactctcc tatctctatt atacgcaaga aaaaataaat
   114901 gagggtcttt atcagttaga tacgactgta aaatacgtat ctgcagtcaa tgattttcca
   114961 ggttcttata aaccagaggg aagtggtagt cttcctaaaa aagaagataa taaagaatat
   115021 tctttaaagg atttaattac gaaagtatca aaagaatctg ataatgtagc tcataatcta
   115081 ttgggatatt acatttcaaa ccaatctgat gccacattca aatccaagat gtctgccatt
   115141 atgggagatg attgggatcc aaaagaaaaa ttgatttctt ctaagatggc cgggaagttt
   115201 atggaagcta tttataatca aaatggattt gtgctagagt ctttgactaa aacagatttt
   115261 gatagtcagc gaattgccaa aggtgtttct gttaaagtag ctcataaaat tggagatgcg
   115321 gatgaattta agcatgatac gggtgttgtc tatgcagatt ctccatttat tctttctatt
   115381 ttcactaaga attctgatta tgatacgatt tctaagatag ccaaggatgt ttatgaggtt
   115441 ctaaaatgag ggaaccagat tttttaaatc attttctcaa gaagggatat ttcaaaaagc
   115501 atgctaaggc ggttctagct ctttctggtg gattagattc catgtttcta tttaaggtat
   115561 tgtctactta tcaaaaagag ttagagattg aattgattct agctcatgtg aatcataagc
   115621 agagaattga atcagattgg gaagaaaagg aattaaggaa gttggctgct gaagcagagc
   115681 ttcctattta tatcagcaat ttttcaggag aattttcaga agcgcgtgca cgaaattttc
   115741 gttatgattt ttttcaagag gtcatgaaaa agacaggtgc gacagcttta gtcactgccc
   115801 accatgctga tgatcaggtg gaaacgattt tgatgcgctt gattcgagga actcgcttgc
   115861 gctatctatc aggaattaag gagaagcaag tagtcggaga gatagaaatc attcgtccct
   115921 tcttgcattt taagaaaaaa gactttccat caatttttca ctttgaagat acatcaaatc
   115981 aggagaatca ttattttcga aatcgtattc gaaattctta cttaccagaa ttggaaaaag
   116041 aaaatcctcg atttaggaat gcaatcttag gcattagcaa tgaaatttta gattatgatt
   116101 tggcaatagc tgaattatct aacaatatta atgtggaaga tttacagcag ttattttctt
   116161 attctgagtc tacacaaaga gttttacttc aaacttatct gaatcgtttt ccagatttga
   116221 atcttacaaa agctcagttt gctgaagttc agcagatttt aaaatctaaa agccagtatc
   116281 gtcatccgat taaaaatggc tatgaattga taaaagagta ccaacagttt cagatttgta
   116341 aaatcagtcc gcaggctgat gaagaggaag atgaacttgt gttacactat caaaatcagg
   116401 tagcttatca aggatattta ttttcctttg gacttccatt agaaggtgaa tcaattcaac
   116461 aaatacctgt ttcacgtgaa acatccatac acattcgtca tcgaaaaaca ggagatgttt
   116521 tgattcaaaa tgggcataga aaaaaactca gacgtttatt tattgatttg aaaatcccta
   116581 tggaaaagag aaactctgct cttattattg agcaatttgg tgaaattgtc tcaattttgg
   116641 gaattgcgac caataatttg agtaaaaaaa cgaaaaatga tataatgaac actgtacttt
   116701 atatagaaaa aatagatagg taaaaaatgt tagaaaacga tattaaaaaa gtcctcgttt
   116761 cacacgatga aattacagaa gcagctaaaa aactaggtgc tcaattaact aaagactatg
   116821 caggaaaaaa tccaatctta gttgggattt taaaaggatc tattcctttt atggctgaat
   116881 tggtcaaaca tattgataca catattgaaa tggacttcat gatggtttct agctaccatg
   116941 gtggaacagc aagtagtggt gttatcaata ttaaacaaga tgtgactcaa gatatcaaag
   117001 gaagacatgt tctatttgta gaagatatca ttgatacagg tcaaactttg aagaatttgc
   117061 gagatatgtt taaagaaaga gaagcagctt ctgttaaaat tgcaaccttg ttggataaac
   117121 cagaaggacg tgttgtagaa attgaggcag actatacctg ctttactatc ccaaatgagt
   117181 ttgtagtagg ttatggttta gactacaaag aaaattatcg taatcttcct tatattggag
   117241 tattgaaaga ggaagtgtat tcaaattaga aagaataatc tttaatgaaa aaacaaaata
   117301 atggtttaat taaaaatcct tttctatggt tattatttat ctttttcctt gtgacaggat
   117361 tccagtattt ctattctggg aataactcag gaggaagtca gcaaatcaac tatactgagt
   117421 tggtacaaga aattaccgat ggtaatgtaa aagaattaac ttaccaacca aatggtagtg
   117481 ttatcgaagt ttctggtgtc tataaaaatc ctaaaacaag taaagaagga acaggtattc
   117541 agtttttcac gccatctgtt actaaggtag agaaatttac cagcactatt cttcctgcag
   117601 atactaccgt atcagaattg caaaaacttg ctactgacca taaagcagaa gtaactgtta
   117661 agcatgaaag ttcaagtggt atatggatta atctactcgt atccattgtg ccatttggaa
   117721 ttctattctt cttcctattc tctatgatgg gaaatatggg aggaggcaat ggccgtaatc
   117781 caatgagttt tggacgtagt aaggctaaag cagcaaataa agaagatatt aaagtaagat
   117841 tttcagatgt tgctggagct gaggaagaaa aacaagaact agttgaagtt gttgagttct
   117901 taaaagatcc aaaacgattc acaaaacttg gagcccgtat tccagcaggt gttcttttgg
   117961 agggacctcc ggggacaggt aagactttgc ttgctaaggc agtcgctgga gaagcaggtg
   118021 ttccattctt tagtatctca ggttctgact ttgtagaaat gtttgtcgga gttggagcta
   118081 gtcgtgttcg ctctcttttt gaggatgcca aaaaagcagc accagctatc atctttatcg
   118141 atgaaattga tgctgttgga cgtcaacgtg gagtcggtct cggcggaggt aatgacgaac
   118201 gtgaacaaac cttgaaccaa cttttgattg agatggatgg ttttgaggga aatgaaggga
   118261 ttatcgtcat cgctgcgaca aaccgttcag atgtacttga tcctgccctt ttgcgtccag
   118321 gacgttttga tagaaaagta ttggttggcc gtcctgatgt taaaggtcgt gaagcaatct
   118381 tgaaagttca cgctaagaac aagcctttag cagaagatgt tgatttgaaa ttagtggctc
   118441 aacaaactcc aggctttgtt ggtgctgatt tagagaatgt cttgaatgaa gcagctttag
   118501 ttgctgctcg tcgcaataaa tcgataattg atgcttcaga tattgatgaa gcagaagata
   118561 gagttattgc tggaccttct aagaaagata agacagtttc acaaaaagaa cgagaattgg
   118621 ttgcttacca tgaggcagga cataccattg ttggtctagt cttgtcgaat gctcgcgttg
   118681 tccataaggt tacaattgta ccacgcggcc gtgcaggcgg atacatgatt gcacttccta
   118741 aagaggatca aatgcttcta tctaaagaag atatgaaaga gcaattggct ggcttaatgg
   118801 gtggacgtgt agctgaagaa attatcttta atgtccaaac tacaggagct tcaaacgact
   118861 ttgaacaagc gacacaaatg gcacgtgcaa tggttacaga gtacggtatg agtgaaaaac
   118921 ttggcccagt acaatatgaa ggaaaccatg ctatgcttgg tgcacagagt cctcaaaaat
   118981 caatttcaga acaaacagct tatgaaattg atgaagaggt tcgttcatta ttaaatgagg
   119041 cacgaaataa agctgctgaa attattcagt caaatcgtga aactcacaag ttaattgcag
   119101 aagcattatt gaaatacgaa acattggata gtacacaaat taaagctctt tacgaaacag
   119161 gaaagatgcc tgaagcagta gaagaggaat ctcatgcact atcctatgat gaagtaaagt
   119221 caaaaatgaa tgacgaaaaa taaccctgag agaggctgga gtctctcttt tttgtgcagt
   119281 ttaggagcta aagggaacag aatggagaaa atggaacaaa tgtgttttct aatctgttag
   119341 actgtatcta gaaaggggaa aattatgatt aaagaattgt atgaagaagt ccaagggact
   119401 gtgtataagt gtagaaatga atattacctt catttatggg aattgtcgga ttgggaccaa
   119461 gaaggcatgc tctgcttaca tgaattgatt agtagagaag aaggactggc agacgatatt
   119521 ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc gaattttaga ctatatccgt
   119581 aagcaggaaa gtcagaagcg tagatacgat aaagaaccct atgaagaagt gggagagatc
   119641 agtcatcgta taagtgaggg
//
LOCUS       DAVMCG010000002       108833 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVMCG010000002 DAVMCG010000000
VERSION     DAVMCG010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 108833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108833
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.002"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            123..2015
                     /gene="pepO"
                     /locus_tag="VYP66_000111"
     CDS             123..2015
                     /gene="pepO"
                     /locus_tag="VYP66_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1849735.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(2138..2767)
                     /locus_tag="VYP66_000112"
     CDS             complement(2138..2767)
                     /locus_tag="VYP66_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1849736.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKYLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFHFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGSATTIAHEKAFNPFF"
     gene            3763..5985
                     /locus_tag="VYP66_000113"
     CDS             3763..5985
                     /locus_tag="VYP66_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1849737.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            6015..6458
                     /locus_tag="VYP66_000114"
     CDS             6015..6458
                     /locus_tag="VYP66_000114"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1849738.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(6725..6910)
                     /locus_tag="VYP66_000115"
     CDS             complement(6725..6910)
                     /locus_tag="VYP66_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849739.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(6929..7342)
                     /locus_tag="VYP66_000116"
     CDS             complement(6929..7342)
                     /locus_tag="VYP66_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849740.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFIIRLETSFEWLLLSGLIFFLA
                     QGLLLFLLIVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMS
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            complement(7473..8180)
                     /locus_tag="VYP66_000117"
     CDS             complement(7473..8180)
                     /locus_tag="VYP66_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEV1849741.1"
                     /translation="MKKSLKIFATSKWFDLFGVALVVGIAIASGYLNSRLDKFVDWGL
                     WTALVPFGLISVTNVGISMLSTRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIIT
                     YPVTFLIYTFAIKKWKASQEGRPNQISQKQVKLAVIIISIIAFLFAFVTNYIGYEGKM
                     NLLAYVTTIAFALSLIANALNALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFY
                     ILNAIGALFVWNDEEVR"
     gene            complement(8299..8949)
                     /locus_tag="VYP66_000118"
     CDS             complement(8299..8949)
                     /locus_tag="VYP66_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1849742.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMVIAKQLYVEKIN"
     gene            9061..9903
                     /locus_tag="VYP66_000119"
     CDS             9061..9903
                     /locus_tag="VYP66_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1849743.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQLHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDNGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            9979..10416
                     /locus_tag="VYP66_000120"
     CDS             9979..10416
                     /locus_tag="VYP66_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1849744.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            10485..10787
                     /locus_tag="VYP66_000121"
     CDS             10485..10787
                     /locus_tag="VYP66_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849745.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSFISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(10878..11951)
                     /locus_tag="VYP66_000122"
     CDS             complement(10878..11951)
                     /locus_tag="VYP66_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1849746.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPSQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPK
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            12107..12784
                     /locus_tag="VYP66_000123"
     CDS             12107..12784
                     /locus_tag="VYP66_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1849747.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            12777..13751
                     /locus_tag="VYP66_000124"
     CDS             12777..13751
                     /locus_tag="VYP66_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1849748.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(13800..15743)
                     /gene="thrS"
                     /locus_tag="VYP66_000125"
     CDS             complement(13800..15743)
                     /gene="thrS"
                     /locus_tag="VYP66_000125"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1849749.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEDEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(15903..16124)
                     /locus_tag="VYP66_000126"
     CDS             complement(15903..16124)
                     /locus_tag="VYP66_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1849750.1"
                     /translation="MELQELVERSWAIRQAYNELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIW"
     gene            16981..17610
                     /locus_tag="VYP66_000127"
     CDS             16981..17610
                     /locus_tag="VYP66_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1849751.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTPDFPEEFKPLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            17751..18020
                     /gene="rpsO"
                     /locus_tag="VYP66_000128"
     CDS             17751..18020
                     /gene="rpsO"
                     /locus_tag="VYP66_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1849752.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            18835..19449
                     /locus_tag="VYP66_000129"
     CDS             18835..19449
                     /locus_tag="VYP66_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1849753.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(19742..20491)
                     /locus_tag="VYP66_000130"
     CDS             complement(19742..20491)
                     /locus_tag="VYP66_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1849754.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            20624..22960
                     /locus_tag="VYP66_000131"
     CDS             20624..22960
                     /locus_tag="VYP66_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1849755.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            23062..23739
                     /locus_tag="VYP66_000132"
     CDS             23062..23739
                     /locus_tag="VYP66_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1849756.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVPHVSE"
     gene            23726..24523
                     /locus_tag="VYP66_000133"
     CDS             23726..24523
                     /locus_tag="VYP66_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1849757.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24540..25643
                     /locus_tag="VYP66_000134"
     CDS             24540..25643
                     /locus_tag="VYP66_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1849758.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25650..25796
                     /locus_tag="VYP66_000135"
     CDS             25650..25796
                     /locus_tag="VYP66_000135"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849759.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            25899..26918
                     /gene="galE"
                     /locus_tag="VYP66_000136"
     CDS             25899..26918
                     /gene="galE"
                     /locus_tag="VYP66_000136"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1849760.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKVMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26920..27885
                     /locus_tag="VYP66_000137"
     CDS             26920..27885
                     /locus_tag="VYP66_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1849761.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAAHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKNKVKRL"
     gene            complement(27936..28142)
                     /locus_tag="VYP66_000138"
     CDS             complement(27936..28142)
                     /locus_tag="VYP66_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1849762.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            28194..28670
                     /locus_tag="VYP66_000139"
     CDS             28194..28670
                     /locus_tag="VYP66_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1849763.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            28679..29350
                     /locus_tag="VYP66_000140"
     CDS             28679..29350
                     /locus_tag="VYP66_000140"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1849764.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            29481..29819
                     /locus_tag="VYP66_000141"
     CDS             29481..29819
                     /locus_tag="VYP66_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1849765.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            29822..30451
                     /locus_tag="VYP66_000142"
     CDS             29822..30451
                     /locus_tag="VYP66_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1849766.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            30691..31842
                     /locus_tag="VYP66_000143"
     CDS             30691..31842
                     /locus_tag="VYP66_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1849767.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32155..32904
                     /gene="truA"
                     /locus_tag="VYP66_000144"
     CDS             32155..32904
                     /gene="truA"
                     /locus_tag="VYP66_000144"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1849768.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFILDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            32894..33667
                     /locus_tag="VYP66_000145"
     CDS             32894..33667
                     /locus_tag="VYP66_000145"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1849769.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            33645..34106
                     /locus_tag="VYP66_000146"
     CDS             33645..34106
                     /locus_tag="VYP66_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1849770.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            34327..35653
                     /locus_tag="VYP66_000147"
                     /pseudo
     CDS             34327..35653
                     /locus_tag="VYP66_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(35780..35983)
                     /locus_tag="VYP66_000148"
     CDS             complement(35780..35983)
                     /locus_tag="VYP66_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1849771.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(35976..37058)
                     /locus_tag="VYP66_000149"
     CDS             complement(35976..37058)
                     /locus_tag="VYP66_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1849772.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSAEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(37184..37966)
                     /locus_tag="VYP66_000150"
     CDS             complement(37184..37966)
                     /locus_tag="VYP66_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1849773.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(37966..39309)
                     /locus_tag="VYP66_000151"
     CDS             complement(37966..39309)
                     /locus_tag="VYP66_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1849774.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(39408..40724)
                     /locus_tag="VYP66_000152"
     CDS             complement(39408..40724)
                     /locus_tag="VYP66_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1849775.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            40917..42143
                     /locus_tag="VYP66_000153"
     CDS             40917..42143
                     /locus_tag="VYP66_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1849776.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            42342..43916
                     /locus_tag="VYP66_000154"
     CDS             42342..43916
                     /locus_tag="VYP66_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1849777.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            44180..44968
                     /gene="codY"
                     /locus_tag="VYP66_000155"
     CDS             44180..44968
                     /gene="codY"
                     /locus_tag="VYP66_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1849778.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            44968..45543
                     /locus_tag="VYP66_000156"
     CDS             44968..45543
                     /locus_tag="VYP66_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1849779.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            45624..45709
                     /locus_tag="VYP66_000157"
     tRNA            45624..45709
                     /locus_tag="VYP66_000157"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45658..45660,aa:Leu,seq:aag)
     gene            45992..47122
                     /gene="ugpC"
                     /locus_tag="VYP66_000158"
     CDS             45992..47122
                     /gene="ugpC"
                     /locus_tag="VYP66_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1849780.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            47632..48390
                     /locus_tag="VYP66_000159"
     CDS             47632..48390
                     /locus_tag="VYP66_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1849781.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            48477..48989
                     /locus_tag="VYP66_000160"
     CDS             48477..48989
                     /locus_tag="VYP66_000160"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1849782.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            49171..50115
                     /locus_tag="VYP66_000161"
     CDS             49171..50115
                     /locus_tag="VYP66_000161"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1849783.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            50124..50801
                     /locus_tag="VYP66_000162"
     CDS             50124..50801
                     /locus_tag="VYP66_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1849784.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            50899..51657
                     /locus_tag="VYP66_000163"
     CDS             50899..51657
                     /locus_tag="VYP66_000163"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1849785.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALSGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            51695..53200
                     /gene="lytC"
                     /locus_tag="VYP66_000164"
     CDS             51695..53200
                     /gene="lytC"
                     /locus_tag="VYP66_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1849786.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYLKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            53697..54215
                     /locus_tag="VYP66_000165"
     CDS             53697..54215
                     /locus_tag="VYP66_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1849787.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            54345..54851
                     /locus_tag="VYP66_000166"
     CDS             54345..54851
                     /locus_tag="VYP66_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1849788.1"
                     /translation="MTKKIVAIWAQDEEGVIGKDNRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            54851..55021
                     /locus_tag="VYP66_000167"
     CDS             54851..55021
                     /locus_tag="VYP66_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849789.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            55053..56285
                     /gene="clpX"
                     /locus_tag="VYP66_000168"
     CDS             55053..56285
                     /gene="clpX"
                     /locus_tag="VYP66_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1849790.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            56294..56881
                     /locus_tag="VYP66_000169"
     CDS             56294..56881
                     /locus_tag="VYP66_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1849791.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            56892..57272
                     /locus_tag="VYP66_000170"
     CDS             56892..57272
                     /locus_tag="VYP66_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1849792.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            57324..58214
                     /gene="rapZ"
                     /locus_tag="VYP66_000171"
     CDS             57324..58214
                     /gene="rapZ"
                     /locus_tag="VYP66_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1849793.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            58211..59188
                     /locus_tag="VYP66_000172"
     CDS             58211..59188
                     /locus_tag="VYP66_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1849794.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFASHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQAILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            59185..60096
                     /gene="whiA"
                     /locus_tag="VYP66_000173"
     CDS             59185..60096
                     /gene="whiA"
                     /locus_tag="VYP66_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1849795.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(60130..61095)
                     /locus_tag="VYP66_000174"
     CDS             complement(60130..61095)
                     /locus_tag="VYP66_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1849796.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEFAITTSK
                     GSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSAV
                     DWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKLE
                     ITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYAI
                     GDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            61231..62088
                     /locus_tag="VYP66_000175"
     CDS             61231..62088
                     /locus_tag="VYP66_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1849797.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            62075..62854
                     /locus_tag="VYP66_000176"
     CDS             62075..62854
                     /locus_tag="VYP66_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1849798.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            62878..64230
                     /locus_tag="VYP66_000177"
     CDS             62878..64230
                     /locus_tag="VYP66_000177"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1849799.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            64304..64678
                     /locus_tag="VYP66_000178"
     CDS             64304..64678
                     /locus_tag="VYP66_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1849800.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            64680..65528
                     /locus_tag="VYP66_000179"
     CDS             64680..65528
                     /locus_tag="VYP66_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1849801.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            65794..66561
                     /locus_tag="VYP66_000180"
     CDS             65794..66561
                     /locus_tag="VYP66_000180"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1849802.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLPDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            66573..67757
                     /locus_tag="VYP66_000181"
     CDS             66573..67757
                     /locus_tag="VYP66_000181"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1849803.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQARGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            67754..69625
                     /locus_tag="VYP66_000182"
     CDS             67754..69625
                     /locus_tag="VYP66_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1849804.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKELSGGVAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(69768..70952)
                     /gene="mntE"
                     /locus_tag="VYP66_000183"
     CDS             complement(69768..70952)
                     /gene="mntE"
                     /locus_tag="VYP66_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1849805.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISASIMFMVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTTIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            71256..73952
                     /locus_tag="VYP66_000184"
     CDS             71256..73952
                     /locus_tag="VYP66_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1849806.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAMDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVILANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEDHVLTGAELNELSDEDFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            73965..74756
                     /gene="yghU"
                     /locus_tag="VYP66_000185"
     CDS             73965..74756
                     /gene="yghU"
                     /locus_tag="VYP66_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1849807.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            74872..75282
                     /locus_tag="VYP66_000186"
     CDS             74872..75282
                     /locus_tag="VYP66_000186"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1849808.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            75294..76889
                     /locus_tag="VYP66_000187"
     CDS             75294..76889
                     /locus_tag="VYP66_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849809.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRVYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            77056..77220
                     /locus_tag="VYP66_000188"
     CDS             77056..77220
                     /locus_tag="VYP66_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1849810.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            77299..78027
                     /gene="yaaA"
                     /locus_tag="VYP66_000189"
     CDS             77299..78027
                     /gene="yaaA"
                     /locus_tag="VYP66_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1849811.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(78305..78853)
                     /locus_tag="VYP66_000190"
     CDS             complement(78305..78853)
                     /locus_tag="VYP66_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1849812.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            79174..79662
                     /locus_tag="VYP66_000191"
     CDS             79174..79662
                     /locus_tag="VYP66_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1849813.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEKADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            79659..80846
                     /locus_tag="VYP66_000192"
     CDS             79659..80846
                     /locus_tag="VYP66_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1849814.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            80839..81204
                     /locus_tag="VYP66_000193"
     CDS             80839..81204
                     /locus_tag="VYP66_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1849815.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            81220..82566
                     /gene="asnS"
                     /locus_tag="VYP66_000194"
     CDS             81220..82566
                     /gene="asnS"
                     /locus_tag="VYP66_000194"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1849816.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            82719..83009
                     /locus_tag="VYP66_000195"
     CDS             82719..83009
                     /locus_tag="VYP66_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1849817.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            83021..83491
                     /gene="ssbA"
                     /locus_tag="VYP66_000196"
     CDS             83021..83491
                     /gene="ssbA"
                     /locus_tag="VYP66_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1849818.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            83523..83762
                     /locus_tag="VYP66_000197"
     CDS             83523..83762
                     /locus_tag="VYP66_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1849819.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            84057..85457
                     /locus_tag="VYP66_000198"
     CDS             84057..85457
                     /locus_tag="VYP66_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1849820.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILIGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            85459..85818
                     /locus_tag="VYP66_000199"
     CDS             85459..85818
                     /locus_tag="VYP66_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1849821.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            85872..86621
                     /locus_tag="VYP66_000200"
     CDS             85872..86621
                     /locus_tag="VYP66_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1849822.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            86611..86910
                     /locus_tag="VYP66_000201"
     CDS             86611..86910
                     /locus_tag="VYP66_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1849823.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGRGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            86981..87916
                     /locus_tag="VYP66_000202"
     CDS             86981..87916
                     /locus_tag="VYP66_000202"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1849824.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            88002..88514
                     /locus_tag="VYP66_000203"
     CDS             88002..88514
                     /locus_tag="VYP66_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1849825.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            88539..89147
                     /locus_tag="VYP66_000204"
     CDS             88539..89147
                     /locus_tag="VYP66_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1849826.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKYQL
                     MQKCRDIFVDSLVVLGYIVQNEDGKYELAIDFDKERLTFYLA"
     gene            89248..89445
                     /locus_tag="VYP66_000205"
     CDS             89248..89445
                     /locus_tag="VYP66_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1849827.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTKE"
     gene            complement(89488..90933)
                     /locus_tag="VYP66_000206"
     CDS             complement(89488..90933)
                     /locus_tag="VYP66_000206"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1849828.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLREQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISNYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            91039..92661
                     /locus_tag="VYP66_000207"
     CDS             91039..92661
                     /locus_tag="VYP66_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1849829.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            92864..94822
                     /locus_tag="VYP66_000208"
     CDS             92864..94822
                     /locus_tag="VYP66_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1849830.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQLIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            94994..95527
                     /locus_tag="VYP66_000209"
                     /pseudo
     CDS             94994..95527
                     /locus_tag="VYP66_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829056.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            95536..96075
                     /locus_tag="VYP66_000210"
     CDS             95536..96075
                     /locus_tag="VYP66_000210"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849831.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALDNLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKG
                     QKLLLLDHLDQENQRLCVC"
     gene            96111..96656
                     /locus_tag="VYP66_000211"
     CDS             96111..96656
                     /locus_tag="VYP66_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1849832.1"
                     /translation="MEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLV
                     TDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIARTYLKDAEILI
                     FDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLEEGKITGSGT
                     HKELLENHERYARFVQEQMIE"
     gene            96813..97907
                     /locus_tag="VYP66_000212"
     CDS             96813..97907
                     /locus_tag="VYP66_000212"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1849833.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            97915..99081
                     /locus_tag="VYP66_000213"
     CDS             97915..99081
                     /locus_tag="VYP66_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1849834.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQIYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            99174..102272
                     /locus_tag="VYP66_000214"
     CDS             99174..102272
                     /locus_tag="VYP66_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1849835.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQVLVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            102320..102937
                     /locus_tag="VYP66_000215"
     CDS             102320..102937
                     /locus_tag="VYP66_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1849836.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            102948..104282
                     /locus_tag="VYP66_000216"
     CDS             102948..104282
                     /locus_tag="VYP66_000216"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1849837.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            104292..104756
                     /locus_tag="VYP66_000217"
     CDS             104292..104756
                     /locus_tag="VYP66_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1849838.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDCKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            104753..105247
                     /locus_tag="VYP66_000218"
     CDS             104753..105247
                     /locus_tag="VYP66_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1849839.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            105328..106983
                     /gene="mltG"
                     /locus_tag="VYP66_000219"
     CDS             105328..106983
                     /gene="mltG"
                     /locus_tag="VYP66_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1849840.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            107054..107536
                     /gene="greA"
                     /locus_tag="VYP66_000220"
     CDS             107054..107536
                     /gene="greA"
                     /locus_tag="VYP66_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1849841.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            107909..108307
                     /locus_tag="VYP66_000221"
     CDS             107909..108307
                     /locus_tag="VYP66_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1849842.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            108756..108833
                     /locus_tag="VYP66_000222"
                     /pseudo
     CDS             108756..108833
                     /locus_tag="VYP66_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT        32107 a        20311 c        24696 g        31719 t
ORIGIN      
        1 tgcgttttat catggaaaga ttttttataa tagctaaaaa ataatagtta aatggttatt
       61 aattgcattc cctagtgatt tttgttaaga taaaggcaaa tacaaatgaa agcgagaaca
      121 agatgacacg ttatcaagat gatttttatg atgctatcaa tggagaatgg caacagacag
      181 ctgaaatccc agcagataag tctcaaacag gaggttttgt tgatttagac caggaaattg
      241 aagacctgat gctggcgaca acagacaagt ggttagcagg tgaagaggtg cctgaggatg
      301 ctatcttgga aaactttgtc aaataccacc gcctagttcg tgattttgac aagagagaag
      361 ctgacggtat cacacctgtc ttaccactcc ttaaagaatt ccaagaattg gaaacttttg
      421 cggattttac agctaaacta gcagagtttg agcttgcagg aaaaccaaac ttccttcctt
      481 ttggtgtatc gccagacttt atggatgcta gaatcaatgt tctatgggct agcgctccaa
      541 gcacaatctt gccagatacg acctactatg cagaagaaca tcctcagcgc gaagaactct
      601 tgactctttg gaaagaaagc agcgcaaatc tcctcaaggc ttatgatttc tctgatgaag
      661 aaattgaaga cttgctagaa aaaagacttg aattggaccg ccgagttgcg gcagtggtac
      721 tctctaatga agaaagttca gaatatgcta aactctatca tccatattct tacgaagatt
      781 tcaagaaatt cgcgcctgcc ctacctttgg atgacttctt caaagcagtt attgggcaat
      841 taccagacaa ggttattgta gacgaggaac gtttctggca agcagcagag caattctaca
      901 gtgaggaatc ctggtctctc cttaaagcaa ccttgatttt gagtgttgtc aatctttcaa
      961 ccagctattt aacagaggat atccgtgttt tgtctggtgc ctacagccgt gccctttctg
     1021 gagttccaga ggcaaaagat aaggtcaaag cagcttatca tctagcacaa gaacctttca
     1081 agcaagccct ggggctttgg tacgcccgtg agaagttctc tccagaagcc aaggcggatg
     1141 tggagaaaaa agtggcaacc atgattgatg tctataagga gcgtctgctt aagaatgact
     1201 ggctcactcc agaaacctgt aaacaggcta tcgtgaagct caatgtgatc aaaccttata
     1261 ttggctatcc agaagaattg cctgcacgtt acaaggataa ggtagtgaat gaaactgcca
     1321 gtctttttga gaatgctcta gcctttgcgc gtgtggaaat caagcacagt tggagtaagt
     1381 ggaaccagcc tgtagactat aaggaatggg gcatgcctgc tcatatggtc aatgcctact
     1441 acaatcctca gaagaacctg attgtctttc cagcggccat tttacaggcg cctttctatg
     1501 acttgcatca gtcatcttct gctaactacg gtggtattgg ggcagtgatt gcccatgaaa
     1561 tttcccacgc ctttgatact aacggggctt cctttgacga aaatggtagc ctcaaggatt
     1621 ggtggacaga gagcgactat gctgccttca aggagaaaac acaaaaagtc attgaccaat
     1681 ttgatggaca ggattcttat ggagcaacca ttaacggtaa attgactgta tcagaaaacg
     1741 tggctgactt gggaggaatc gcagcagcgc ttgaagcagc taagagagaa gcagacttct
     1801 cagcagaaga gttcttctac aacttcggtc gcatctggcg catgaaaggt cgtccagaat
     1861 ttatgaaact tttggctagc gtcgatgtgc acgcaccagc caaactccgt gtcaatgtgc
     1921 aagtaccaaa cttcgacgat ttctttacaa cctatgatgt caaagaagga gacggaatgt
     1981 ggcgttcacc agaggagcgc gtgattattt ggtaatacaa aaaatctagt catcagaaaa
     2041 aaggcatcca atcacgtgtg aaaaccttga taggatgcct tttataatag aaagatttgc
     2101 tggatagttt acttaaattt cgattgtcat catcttgcta aaaaaaggga ttgaaggcct
     2161 tttcgtgagc gatagtagta gctgaaccat gtcctggata gacatcgtag tttggtaggg
     2221 tgaagagttg ggtctggata ctatgaagga gttgctccat gctaccagtc ggaaggtcgg
     2281 tccgtccgat agtttcgcgg aatagagcat ctcccgtcaa gactaggtga gcatcaggaa
     2341 agactaggga aacaccaccg atagagtgcc ctggggtcgg cagaacctta aaatgaaatt
     2401 cctctagttg gtattcttcg tgaaagacaa aggtgtgttc tgcaggtttt gtgaccacat
     2461 ctgccatatc atcgtggcga gggagaccgg agagattatc gacaggagtg tagagccagc
     2521 tggcttcgct ctctgcgata tagacaggag gattgccaaa cgtctcgcga accaagtcca
     2581 gactcatgat atggtcataa tgggcgtggg tcaagagaat agcacagatc ggtttgttga
     2641 tcttctcgat tgtctgacga atggcttccc aatgactacc aggatcgacg acgatgaggt
     2701 acttttcgcc ttctagataa taggtatttt cataggcaac aggattcacg gttttatgga
     2761 ttttcatact agctccaatc tcaaagaatg tactaatact cttcgaaaat ctcttcaaac
     2821 tgcgtcaact ttatctgcaa cctcaaagca gtgctttgaa cagcctgcgg ctagctttct
     2881 agtttgctct ttgattttca ttgagtataa attaagtata gcacagttag ggagaatagg
     2941 taaggattta aaatgaactt aaaaaccagc atgactagat gaagacaggc tggttatcaa
     3001 tttatcaata ttggaaaggt gtcaattgcc cttcataggt tgcataaact ccgtcattag
     3061 cttgtttgat agacgtgatg tttagagtgc taccgtagtt ggcttctcat ttgtcgctat
     3121 attcactata agttatccta ctgggcaggt tctggtcgtt agcatagtat tgaacgactg
     3181 ttttttatag ctttgctggc tgaataggaa caggcagcaa actcctaaca ttaggagagc
     3241 aaagatagaa atagcagttt ttttcatagg tattctcctt ataaactaaa ggatagaaga
     3301 aagtatcttg aggattttta tactcttcaa aaatctcttc aaaccgcgtc aacgtcgcct
     3361 tgccgtatat atgtgactga ctttgtcagt cttatctaca acctcaaagc agtgctttga
     3421 gcaacctgcg gctagtttcc tagtttgctc tttgattttc attgagtatt aattccaaaa
     3481 tccagtcaag gtaccagtgt atgtgatacg agttccaccg tttatctttc gtatcttcaa
     3541 tggaattggg gaaatcagaa agtctttggg ttacaatatg gtttccgttc ttctatctct
     3601 ccttctatca cctaagttta aaatctaact tcgtagtata ttatgggcca ataattcaga
     3661 attatcaagc aattttgaat tatttttttc ttattctgtt ccaatctagt tttcatattc
     3721 ttaaaaaagt gataaaatgg taggaagaat tggagagtag agatgccgaa agaagtgaat
     3781 ttaacaggcg aagaagttgt cgctttaacc aaagaatatt taacggaaga ggatgttcat
     3841 tttgtccata aggccttggt ctatgctgtt gaatgccaca gtggtcaata tcgcaaatca
     3901 ggcgagcctt atatcattca ccctatccaa gtggcaggta ttttagctaa gctaaagctg
     3961 gatgctgtaa cagtagcttg tggattcttg catgatgtgg tggaagatac agatgcgacc
     4021 ttggacgatt tggaaagaga gtttggtcct gatgtgcggg tgattgttga cggagttacc
     4081 aagcttggca aggtcgagta caaatcgatc gaggagcaat tagcggaaaa tcatcgcaag
     4141 atgctcatgg ccatgtctga ggacatccgc gttattttgg tcaaactgtc tgaccgcttg
     4201 cacaatatgc ggaccctgaa acatcttcga aaagacaagc aggagcgtat ttccaaagaa
     4261 accatggaaa tctatgcccc acttgcccat cgtttgggga tttccagtgt caaatgggaa
     4321 ttagaagact tgtctttccg ttatctcaat ccaacggagt tttacaagat tacccatatg
     4381 atgaaggaaa agcgcaggga gcgtgaggcc ttggtggatg aggtagtcac aaaattagag
     4441 gagtatacga cagaacgtca cttgaaaggg aagatttatg gtcgtcccaa gcatatttac
     4501 tcaattttcc gcaaaatgca ggacaagaga aaacggtttg aggaaatcta tgatctgatt
     4561 gctattcgtt gtattttaga tacccaaagt gatgtttatg ccatgcttgg ttacgtgcat
     4621 gaattttgga aaccgatgcc aggtcgcttc aaagactata ttgccaaccg caaggccaat
     4681 ggttatcagt ctatccatac gactgtttat ggaccaaaag ggccgattga attccagatt
     4741 cgaaccaagg aaatgcacga ggtggctgag tacggggttg cggctcactg ggcttataag
     4801 aaaggtataa aggggcaagt taacagcaag gaatcagcta ttggaatgaa ctggatcaag
     4861 gagatgatgg agctccaaga ccaggctgat gatgctaagg aatttgtgga ctctgttaag
     4921 gaaaactatt tggctgagga gatttacgtt tttaccccag atggagctgt ccgttccctt
     4981 cccaaagatt caggaccgat tgattttgcc tacgaaatcc ataccaaggt cggtgaaaaa
     5041 gcaactggtg ccaaggtcaa tggccgcatg gttccactga caaccaagtt aaagacaggg
     5101 gatcaggttg aaattatcgc caacccgaac tcctttggac ctagccgtga ctggctcaat
     5161 atggtcaaga ctagcaaggc gcgcaataag attcgccagt tctttaaaaa ccaagataag
     5221 gaattgtctg tcaacaaggg tcgtgagatg ctgatggctc agttccaaga aaatggctat
     5281 gtggcaaata aatttatgga caagcgccac atggatcaag ttctgcaaaa gaccagttac
     5341 aagacagaag actccctctt tgcggccatt ggttttgggg aaatcggtgc gattaccgtc
     5401 tttaatcgtc tgactgaaaa ggaacgccgt gaggaagagc gtgccaaggc caaggctgag
     5461 gcagaggagc ttgtcaaagg tggcgaggtc aaggttgaaa ataaagaaac tctcaaggtc
     5521 aagcatgagg ggggagtggt tattgaaggt gcttctggtc tcctagtgcg gattgctaag
     5581 tgttgtaacc ccgtgcctgg tgacgatatt gttggctaca ttaccaaggg tcgtggtgtg
     5641 gctattcacc gtgtggactg tatgaacctg cgtgcccaag aaaactacga gcaacgtctc
     5701 cttgatgtgg aatgggaaga ccagtactct agctcaaata aggagtatat ggcccatatc
     5761 gatatctacg gtctcaaccg tacaggactg ttgaacgatg tactgcaagt tctttcaaat
     5821 acaaccaaga atatttcaac ggtcaatgcc caaccaacca aggatatgaa gtttgctaat
     5881 atccatgtgt ccttcggtat tgccaacctc tctacactga ccacggttgt cgataaaatt
     5941 aagagtgtgc cagaagttta ctctgtcaaa cggaccaacg gctagttgtc ctagctctta
     6001 ctagaaaggc tattatgaaa atcattatcc aacgggttaa aaaagcccaa gtgagtatag
     6061 aaggccagat tcagggaaaa atcaatcagg gacttttatt gctggttggt gttggaccag
     6121 aggaccaaga ggaagatttg gactatgctg tgagaaaact ggtcaatatg cggatttttt
     6181 cagacgcaga aggcaagatg aacctgtctg tcaaagatat tgaaggagaa atcctctcta
     6241 tttctcagtt taccctcttt gcggatacta agaaaggcaa tcgtccagcc tttacagggg
     6301 cagctaaacc tgatatggca tcagacttct atgatgcttt caatcaaaaa ttagcgcaag
     6361 aagtgcccgt tcagacaggt atctttggag cagatatgca ggttgagctg gttaataacg
     6421 gacctgttac cattatccta gatactaaaa agagataaga aagaccaagc ccagtcggct
     6481 tggtctttct catctatcat aaaatactcc aaaaagaaat cggttcttga tatgcttggg
     6541 ggaagtctct tttcaggctt tggcagatgc gataggaagg gatgagatgt cctaggatga
     6601 ggagagttcc ctgaaggaaa agtggaatat cacttaaaga caccaaggag agaatcatca
     6661 ggctatccca taggagaatt tgtaaagcaa aacgccagaa tctcggtcta atctgggaat
     6721 agagttaact aaagtggtca caaagttggt ttgaaagata ggtcaatagc acaggatgaa
     6781 agaaaatgag ccaaccgcta taaatcaaaa tccagtccca agtaagcccc cttttaaatg
     6841 tcaaaaatgc cagcatgatt ccatcaatga caaggagttg aatggttttg atgaagatga
     6901 tttttttcat gctaaaacct ccttttcctt agagacactc ccataaagag atgtgtttgt
     6961 cgtaaaagtc tggatagttt tctcttaggt agtcagctgt catataataa aaagtagaat
     7021 ggcaagcagt gataattgac ataagagatg aaaaacgctg agaactaatg aaggctaaga
     7081 gaacaaaaaa tagaaaatca atggtgagaa cccctaaata gtagaagcga atctttttat
     7141 tgatttgagg ataaatctca gcgaattgat gtttgagtcg gacgatcaag agaaatagca
     7201 ggagtccttg agcaaggaag aaaattaaac cagagagcaa gagccactca aaagatgtct
     7261 cgagtctaat gataaaaaat gcaaatagta gcaaatcaat aactgcaatt gctataaaat
     7321 ggattctata gagttttttc atgacaagac ctccctcttt tatctaactt cattctactc
     7381 caaaagaatg ggagttacaa ctaaaatgat aaaaatagca gaagggagat tctcttaagt
     7441 tggctagtat tctttatttg agtttccttc tattatctaa cttcttcatc attccagaca
     7501 aataaagctc cgattgcatt gaggatataa aagatgtatt taccgatatt ggcgaagttt
     7561 ccttgaatac cagcttttgt cagctgaacg aaattgtaaa tcaaccaaaa gccccactga
     7621 gttgttagtt ttaatgcatt caaagcattg gcaatgaggg atagtgcaaa ggcaatagtt
     7681 gttacgtagg caaggagatt catcttgccc tcatatccga tatagttggt cacaaaggca
     7741 aagaggaagg cgatgatgga aatgatgatg accgccaatt ttacctgttt ttggcttatt
     7801 tggttgggtc tgccttcttg cgaagctttc catttcttta tagcaaaggt ataaatgagg
     7861 aaggtgacgg gataggtaat gatggccgcc ttatttccaa ggatataatc aatagcaccg
     7921 gacaaaatgg tattaacaat accaaagtaa tttccccatt tgcttaattt ccccgtgaaa
     7981 cgagtggaca acatggaaat cccaacgttg gttacggaaa tcaatccaaa gggtacaaga
     8041 gctgtccata gtccccagtc tacaaattta tcgaggcgtg agttgagata accagatgca
     8101 atcgcaatcc caacgaccaa agcaaccccg aagaggtcaa accatttaga tgtagcaaaa
     8161 atttttagtg attttttcat aggttaaact acctttcttt ttttttcaaa tattctacca
     8221 ccaaatgaaa gtaaaataaa atgatagaaa taaaaccctg aaaataaaac tttcagggtt
     8281 ggtaggggac ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgaccat
     8341 attcacttgt aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa
     8401 ctgcttgact tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat
     8461 gtcaaaacta tcgtgcaccc gagtcaggcg gtaggcgcca gcttccttga tatcagctag
     8521 tgggaggtta ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg
     8581 gcaggtttta gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt
     8641 gtgttccaag acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac
     8701 tagaaaaact tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag
     8761 gtcagtcagt agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg
     8821 tttgatcatt tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt
     8881 ggtaatctta tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt
     8941 tggggtcatt cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat
     9001 ttctctagct gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat
     9061 atgacgaaaa tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt
     9121 ttggcagatg ctcggcagct aggagtggat gaatactggc ttttgggaga tattctcatg
     9181 ccagggacag gacgtagaag gattttggac ttgttggatc aactaccgat tacggctaga
     9241 gttttgggaa actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggatagtact
     9301 cgccccagtc aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta
     9361 gaagaaattg aagtgctcca caatcaacct cttcaacttc atcgtcagtt tggggatttg
     9421 acggtgggaa ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact
     9481 ggcaaacaag aggagtttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat
     9541 ggacatattc accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg
     9601 ggttcgattg gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag
     9661 tatatgattt tggagtttga tgacaatggc ctggtagata tggacttccg acgggtagac
     9721 tacgatgtgg cagctgaatt gcagctggct aaagacctga gacttcccta ttttgaggtt
     9781 tattatgaaa gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa
     9841 ttggctcaga aagagggctg cgatcgggag ttagacgact ggttgaaaag tggtaacgat
     9901 tgacattaca actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct
     9961 cgtaaaaagg agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg
    10021 ataatcattg ccctcgaggg gaaggaaagc aaggtgacca gtgattttct ggctgctagt
    10081 gtcggggtca atcctgtcat tatcagaaag atcttgtccc agttgaagaa ggcagagctg
    10141 atttcagtag cgcgtggaac gggcggaaca gagattgtca aggaccttaa ggatattagt
    10201 cttttagatg tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc
    10261 catgacaatc cgaatcccaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa
    10321 aaattggaga gaattcagtt gactatggag gcagaacttg gtcagaccag tctagaaaaa
    10381 gtcgtggccg atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttt
    10441 ctttggataa ttatgataaa atgtagctat taaaggagta agaaatgtat cttgttatag
    10501 gaattgtatt agcctttata gtgtcatttt ggaaggataa tagaagtttg tggaatccag
    10561 tattattttt attatccttc atttcaagtt atttttatct atcctacctt ttttataaaa
    10621 atggatacga gaatgttcag ttagcttttt atgtatttgc ctttgtctta cttccttttt
    10681 tgctttttct aagtggcatc tttttaatct ataatggggt cattttgttg aaacgagagg
    10741 gacgttccaa gccccattat ctctcaatgc tctttgattt ttattgacta ttagattcta
    10801 tttaaaaaga cttagaatgc acatgaaagt atgtattcta ggtcttttgt tttgtataca
    10861 tttaattttc aagagtatta tctatttttc catgcatggt aacgagtatc aatcaataac
    10921 tgggtaaggc gacccaaggt ttctctttct tttggagtga gggattgagc ttggacaaag
    10981 agatgatgaa tgtattcaag cgcctttaag gaagccaagt cattgataga gctaatacca
    11041 gcatcaagaa tagtgccaaa gaagaggtcg aagtagagct gaagttcttc gtcagggact
    11101 gtggccaccc attctttaaa ggttgtgtct acttgccggc tatcactgtt ggtcttatcc
    11161 agttgaacga agtgcttgtc ctcaatctgc caactaaagg tatcgtgctg ggcgatgcca
    11221 cccagggcag tactctgaac gatgatttgg tgagcaggaa tttccagcat cataccgata
    11281 atggaacctt gtggaatgaa tatcttgctt ctatccatta tcctttgata acccgcagtc
    11341 tgtgtcaatt cttgatggag accaggtgca tcaaatgtat aaactgctgt gatctgattt
    11401 tgcaaacttt gctcaatttg gctagcagca tagatagcga gatttcctcc cttggaatgc
    11461 ccagccagaa taaccttttg cttaggatga tgggcaaaaa agttctttaa atagcgaagg
    11521 gcgtgctttt gagaaggaat ttccttcata taggtcaggt ggaaatcttc cttccagcca
    11581 atgatactgt catctgtccc acgaaagaca atcagatagg tatcgaggct gacacgataa
    11641 gtcatagccg caaattgctt ttgcagttca gggtcgatgt cgttgataaa atgggagagt
    11701 ttgcaatttt tgaagcgctt gtgttgagcc aattcatcta ataattgaag gcgatttttg
    11761 ctagtaagca tggtgggctc tcttggaacc tgaggtgcta gatctaaaag acgttgagga
    11821 agtgtggaga ccagattatc aaaggagagg taggtgattt ctattaaggt tagaatgtct
    11881 aactcattca agggaaggtc gtaataagaa tcatatgcga catctttcag atagtcaaaa
    11941 atattggcca taagagctcc tttcttttta tttatcttag caaatttccc tcaaattagc
    12001 tagtagcata gcctgtttgt gctggctaaa aacaggctat ttcaaattca gtttcagacc
    12061 atctagcatg gaaaaatctg ttataataat ggaaaaggag aagcgcatgc acaagatttt
    12121 attaatagaa gatgatcagg tcattcgtca acagattggg aaaatgctct ctgaatgggg
    12181 atttgaagtg gtcctggtag aagactttat ggaagttttg agtctatttg ttcagtcgga
    12241 acctcatctg gtcctcatgg atattggttt gcccttgttt aatggttatc actggtgtca
    12301 ggaaatccgc aagatttcca aggtacctat catgtttctt tcttcgagag accaggctat
    12361 ggatattgtc atggcaatca atatgggggc ggatgacttt gtgaccaagc cttttgacca
    12421 gcaggttctt ttagctaagg ttcagggctt gttgcgtcgt tcctatgagt ttgggcgtga
    12481 tgagagtttg ctggaatatg ctggtgttat cctcaatacc aaatccatgg atttacatta
    12541 tcaagggcaa gtcttgaatt tgaccaagaa tgaattccag attttacgcg tgttatttga
    12601 gcatgcaggc aacatcgtag cacgtgacga cctgatgcgg gaactttgga acagtgactt
    12661 tttcattgat gataataccc tctctgtcaa tgtggctcgt ttgcgtaaaa agttggagga
    12721 gcagggattg gtaggattta tcgagaccaa gaaaggaata gggtatggat tgaagcatgc
    12781 ttgattggaa acaatttttt ctagcctatc tgcgctcccg tagtcgtctt tttatctatc
    12841 tgctttcttt ggcatttctt gtcttactct ttcagttttt atttgccagt ctaggaattt
    12901 acttcctcta ctttttcttc ttgtgttgct ttgtaaccat attatttttc acttgggaca
    12961 tattggtgga aacgcaggtc tatcgccagg aacttctcta tggagagagg gaagccaagt
    13021 ctcctttgga aatagcttta gcagaaaaat tagaagcgcg tgagatggaa ctctatcagc
    13081 agaggtcaaa agcagaaaga aaactgacgg atttgctgga ttactatacc ttgtgggtcc
    13141 atcagataaa gacccccatt gcagccagtc aactcttagt tgcagaagtg gtcgaccgcc
    13201 aactgaagca gcagctagaa caggaaattt tcaaaatcga ctcctatacc aacctagttt
    13261 tacagtacct gcgtttagaa agtttccatg atgatttggt cttaaagcag gttcaaattg
    13321 aggacttggt caaggaaata attcgtaaat atgctctttt ctttattcaa aaaggcttaa
    13381 atgtcaatct acatgacctt gataaagaaa tcgtgacgga taaaaagtgg ctgctagtgg
    13441 ttattgagca aatcatctca aacagtctca agtacaccaa ggaaggtggt ctggagattt
    13501 atatggatga ccaagagctt tgtatcaaag atacgggaat cgggataaaa aacagtgatg
    13561 tcctccgagt atttgaacgt ggcttttcag gatacaatgg ccgtttgacc cagcagtcct
    13621 ctggacttgg cctttatcta tctaagaaaa tttctgaaga actggggcac cagattcgta
    13681 tcgagtctga ggtcggaaaa ggaacgacag tgcggattca gtttgctcaa gtgaacttag
    13741 tccttgagta aaaatagatg agaaaaagcc tccagattgg aggcttttat gctagactct
    13801 tatttctcaa cgcgtgattt gttggcgata tcagctagga tagcttgaac aaaattatca
    13861 actgagacag tttgtgtttc tttttggccg tagcgacgaa cgttgactgt ttcgtcttcc
    13921 atttctttgt ctccaacaat taattggtaa ggaatcttgc tagtttgtga agcacggatc
    13981 ttgaactgca ttttttcatt gcgctcatct acgtctgcac ggacaccgcg gtcacggagt
    14041 ttcttggcta cttcccaagc gtagtccacg tgtttttcgt tagatactgg gataagggtt
    14101 acttggtgtg gtgccagcca tgttgggaag gcacccttgt agttctcaat caagatagct
    14161 gtgaagcgtt ccatagttga gataacccca cggtggatca tgactggacg gtgatcttcg
    14221 ccatcagctc cgatgtattt gaggtcgaag cgttctggca acaagaaatc aagttggata
    14281 gtagaaaggg tttcttcttt tccaagggca gttttaatct ggatatccaa ttttggtccg
    14341 tagaaggctg cttcatcttc ggcttcaaag tagtccacgc ccatttcatc aagggctgca
    14401 cgaagcatgg tttgggcatt ttcccacatc tcatcgttat caaagtactt atgagtatct
    14461 tgagggtcac gaagagagag gcggaagcgg tagtcagtca agttgaagtc ttcataaaca
    14521 tcgataatca actgaagggc acgttggaat tcttcttgga tttgttctgg agtaacgaat
    14581 aggtgaccgt cgttgagtga catttcacgt acacgttgaa ggccagtgag ggcaccagat
    14641 ttttcgtaac ggtgcatcat accgatttca gcgatacgga ttggcaattc acggtaagag
    14701 tgaacatggt gtttgaaaac ttggatgtgg tgcggacagt tcattggacg aaggacaaat
    14761 tcttccccgt cacccatgtc catggttggg aacatgtctt cttggtaatg atcccagtgg
    14821 ccagaagtct tgtaaagctc aacagaagca agtggtggag tgtagacgtg ttggtagcca
    14881 gaagccaact ctttgtttac gatgtagcgt tccaattcac gacggatagt cgcaccattt
    14941 ggcaaccaga atggcaaacc ttgtcccact tcttgtgaaa tcataaagag gtcaagctct
    15001 ttaccaagtt tacggtggtc acgttcctta gcttcttcac gcatttgaag gtagtttttc
    15061 aagtctttct tgtcaaacca agctgtaccg tagatacgtt gcatcatagc gttgtcgctg
    15121 tttccacgcc agtacgcacc agctacatgg agaaggtgga agatttggat acgacctgtt
    15181 gatggaacat gaggtccacg gcagaggtct acatattcac cctgacgata gatagtcaaa
    15241 ccgccttcgt cttctgagtg ttcttcaatc aattccaact tgtaagggtc atttttgaag
    15301 atttcacgtg cctcgtcttt agtcacttct tcacgaatag atgggaagtt ttctttgacg
    15361 attttttgca tttcttcttc gatacgagga aggtcttcgt tagagatttg accagctgtg
    15421 ttgtcagtat cgtagtagaa accatcttcg atggctggac caactcccaa gtgaatgtct
    15481 gggaaaagac gacgagctgc ttgggcgaac aagtgagctg ctgagtgacg caagattgga
    15541 agggcatctt cgtgatcagg tgtcacaatt tcgatgcttc catcttcagt gatagcgcga
    15601 gtagtgtcga tgagtttgcc gttgaattta ccagccaagg cttttttagc tagggaattg
    15661 ctgatagatt gggcaatttc aaaagttgtt acgccagatt cgaattcacg aacagcgcca
    15721 tctgggaaag taatgttaat catgatgttc tcctttttta ttatttcata gtttctaagc
    15781 attgattttt tatcagcaga ctacttccaa gtcctaacgt tcaattgctt ttctttatca
    15841 gagaggaagt tttccatttc cgtcagaatg tctatatcca aacgttgaga aagttctaat
    15901 agtcaccaga tattttctga aagtttttgt tccagtgtgt agggtgtttc atcatagtag
    15961 cgtccttgtt ttgtcatcac cagtcgttgg aaatttccaa tatcattaga taaagccaag
    16021 aggtcttctt ctaccgtcca cttggaatca tgatgcttaa cttccagttc gttataagct
    16081 tgtcggattg cccaactgcg ctccactaat tcttgcaact ccataattag tatcctaata
    16141 aaaaaatgcg acatcctcga aaggacgtcg caacgtggtt ccaccttcat ttatgtacct
    16201 caaaagagag ggacacctct gattggctct aacgtggcca ccgttttatg ttttcataaa
    16261 aaactcaaga gtagtatcag tttagacttc ctatgcgttt ccagcaacca cgcactctct
    16321 agtagaaagg gactaagtga cttgtctcta tggattatta tagcatgatt gtgagatttt
    16381 tcaaggattt tgtgaaagtt ttttgttttt cattttttgt agaatatgct tgatgctaat
    16441 accagaatcc atgcccacca gagcaactgt ttcatagatt agcaagtaaa ttagtataaa
    16501 ctcaccaaag gttatgatag taaagtaaaa gagcagtccg ttaccaacta accatcaaag
    16561 tgagaaacgg aaacggtagc tatagagtaa cgatacaatc aagattacca gaggtgtaaa
    16621 gaagagaaga ttgtttatat agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    16681 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    16741 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    16801 tagcatattt aaaacaagaa agtaaatttg ttgacaaaga agattttttt tcactagaat
    16861 catggttagt tttcttggta gaaatatttt gataataatt aagcaagact attgacattg
    16921 attattaaga gtgtcacaat tgctgtaact aaaataatta caacaagaga ggtataaaaa
    16981 atgaaactag cagttattgc agcaaatgga caagcgggga aagcaattgt tgaagaagca
    17041 gtcaaacgag gacatgaagt aacggctatt gttcgttctg aaaacaaaag tcaagctgag
    17101 tctattatta aaaaagattt atttgagttg acaaaagatg atcttactgg atttgatgct
    17161 gttatttcag cgtttggtgc ttatacacca gatacgctac cgctccatag caaatcaatc
    17221 gaactattta atcagcttct tgctggaaca cagacacgtt ttctagttgt agggggagca
    17281 ggaagccttt atatagatga aacaaaaacg acacgacttt tagatacgcc tgattttcct
    17341 gaagaattta agccactagc aaaagctcaa gcggatgaat ttgatcttct tcgtacaaaa
    17401 aataatctca actggacttt tgtcagtcct gctgtagatt ttattcccga tggtgaaaaa
    17461 acaggaaact acattctagc aggagaaatt tttactacta atggaaaagg aataagccag
    17521 attagttatg cagattatgc tattggattg gtagatgaac ttgaaaaagg tcatcatata
    17581 aaagaacgta tctctttact tgaaaaataa taactatgag agtattaatg tttgacagaa
    17641 aatttaaatc ttggtaaaat agggattgtc gtaaagacaa ataacttctt cttggttaca
    17701 ggcatgccaa cctgtcactc ggatgaagcc aaataaaaag gagaaacatc atggcaatct
    17761 caaaagagaa aaaaaatgaa atcattgcac aatatgcacg tcacgaaggt gatacaggtt
    17821 cagtagaggt tcaagttgct gtccttactt gggaaatcaa ccaccttaac gaacacatca
    17881 aacaacacaa aaaagaccac gctacttacc gtggattgat gaaaaaaatc ggtcgccgtc
    17941 gtaacttgct tgcatacttg cgtaaaaacg acgttaaccg ttaccgtgag ttgatcaact
    18001 ctctaggact tcgtcgctaa ttcaagatac aaaggccgtc aaaagcacaa agcaaaaata
    18061 ggaaaattga cgaagaaact tcagtttcta ggagatttta tcttttttgc caagtgctta
    18121 ggccgtgttc aattgagcat atcttgataa tgaagctact ctaaattggg tagctttttt
    18181 gcgttgtcac cttacctcgc tatactcaag tataatcttt ggttacggtt cctagcactg
    18241 taaggtaaaa taaaccagct tttctccctt cggggagatt ttttttgttt cactgaaagt
    18301 ttcgtacgat cttcgcctcg tcgcctagtc tataaacgat ttatctagca agaatcatga
    18361 tgctaagggc gtcaaaaatc cgtatgaaaa tagggaaatg acacagtgtt cgatgagcac
    18421 aaggagtttc atctttttca ctaggatttt agcccgggct caaatcagct ctctgacttc
    18481 agagggcttt tttattgagg ttttatcggt aacaattttg gagactacaa aaacctcaaa
    18541 cggtatcagc taattacacc ataaaggtgc gcagttactc ggcttttcaa gccgagtagc
    18601 tgtatgcaag ccccctagaa gagcccactc tttacaaagt aaagtatagt atgttatact
    18661 ttacatggaa gtagtcactg aattccagtt agaaattact ttgtaactac gttttgagga
    18721 ggagtaaaat gctttcctac gttcgacatt acccactagc gatagctaaa ttaatgtgtc
    18781 tgtgctctcc taaaatctgc tgatttatta ctgactaata caggagtttt ttttatggga
    18841 cagacaatca tatctgctat tggtgtttat atttccacca gtatcgatta tttaattatt
    18901 ttaattattt tatttgcaca gctatcacag aataaacaga aatggcatat ttatgcgggg
    18961 caatatctag gcacaggctt acttgtaggg gcgagtttag ttgctgctta tgtcgttaat
    19021 ttcgtgcctg aagaatggat ggttggattg cttggtttaa tccctatcta tttagggatt
    19081 cgctttgcaa ttgttggaga agatgcggaa gaagaagagg aagaaattat tgaaagatta
    19141 gaacaaagca aggcaaatca actgttttgg acagttacat tgctgacaat tgcgtctggc
    19201 ggagataatt taggtatcta tataccttat tttgcttcgt tagattggtc acagaccctc
    19261 gtggccttgc ttgtgtttgt aatcggcata attatctttt gcgagattag tcgggtgtta
    19321 tcctctattc cgttaatatt cgagacaatt gaaaaatacg agcgaatcat tgtgccctta
    19381 gtattcattc tacttggact atacatcatg tatgaaaatg gcacgataga gacttttctg
    19441 atcgtgtaga tttttttgtt tcactaggat tttagcccga gctcaaatca gctctctgat
    19501 tttcagaggg ctttttcatt gagtataaat ggacaatctt aaagttactc tattgtagag
    19561 tggcttttga tttgattagg agattcttat aaatatagta aaatgaaaca aaaacaggac
    19621 aaatcgatca ggacagtcaa atcgatttct aaaaatgttt taagaagtag aggtgtacta
    19681 ttctagtttc aatttgatat ataaatgaaa accttagctg tttggccaag gttcatttct
    19741 tctatgcaag ttcttctctt ttcttatctg ggttccagat gaagcttgcg ataaagctaa
    19801 agatgatggt taggatagcg aggataatag caaggatgag ggcagggatg cggataaacc
    19861 accagagtgg atttggtttt ttatcattgt gccattgttt cgtttcttcg tccagacgtt
    19921 ggaattctgt ttgaatacga ttggcgactg tttcaatgcc ttcatcattc attttcttga
    19981 tatctgagat atcgattgga tttccaaagt tcatatcgac acgttcacgg ctaatcaagc
    20041 ccttcaaagt catgggaccg gtgtaggtaa ccggcatgat acggaccttg gccattttgg
    20101 caatcagtgc tgcgcccccc ttgacatcgt ttgagtggcg gctaccactt ggaaacatga
    20161 tgagagagcg gtcacttttt ttgagaacgt tgataggata tttgatggct gaggcgctgg
    20221 gattttcacg gtcgatggga aaggcgccac acatacgaat ccaccaacca aagatacggt
    20281 tggtaaagag ttcttttttt gccataaaga tgaactgttt tggcttggtc gcaaaggcca
    20341 tataaacagg atcccaccag gtacggtgag gcgcaactaa aatataattt tcatcttgat
    20401 taggaatttt atcagtatta tgatagtgag cattgccatt gatggaccat aagagcaata
    20461 caactaatcc acgcaaataa gtataaaaca tgcgatctcc ttcgattgtt ttcttgttat
    20521 tattatacct tatcaaagga gggctggcaa acttttccct tgactagatg catatttggg
    20581 atgaaattag aattctgtta aaaaaaatga tataatagaa tttatggata aaaataagat
    20641 tatgggatta acccaaagag aagtcaagga aagacaggct gagggtttgg tcaatgactt
    20701 taccgcatca gccagtacca gcacttggca aatcgttaaa cgaaatgtct ttaccctttt
    20761 taacgctttg aactttgcca ttgctttggc ccttgccttt gtgcaggctt ggagcaatct
    20821 ggtcttcttt gctgttatct gctttaacgc tttttctggg attgtgaccg agctacgagc
    20881 caaacacatg gtggacaagc tcaatctcat gaccaaggaa aaggtcaaaa ccatccgtga
    20941 tggtcaggaa gttgctctta atcctgaaga attagtgcta ggagatgtca ttcgtttgtc
    21001 tgcaggagag cagattccta gtgatgcctt ggttttggaa ggctttgcgg aagtcaatga
    21061 agccatgtta acgggagaaa gtgatttggt gcaaaaggaa gttgacggct tacttttgtc
    21121 aggaagtttc ctagccagtg ggtcagtttt atctcaagtt caccatgtcg gtgcagacaa
    21181 ctatgctgcc aaactcatgc ttgaggctaa gaccgttaaa cccatcaact cccgtatcat
    21241 gaaatcgctg gacaagttgg ctggttttac tgggaagatt atcattccct ttggtctggc
    21301 tctcttgctg gaagccttgc ttttaaaagg cctgcctctc aagtcatctg ttgtaaattc
    21361 gtcgacagct cttttgggaa tgttgcctaa gggaattgcc cttttgacca ttacttcgct
    21421 tttgactgca gtgattaagc taggtttgaa aaaggtcttg gtgcaggaga tgtactctgt
    21481 tgagaccttg gcgcgcgtgg atatgctctg tctggacaag acgggcacca tcacccaagg
    21541 aaagatgcag gtggaggctg ttcttccact gacggaaact tacggtgaag aggctattgc
    21601 cagcatcttg actagctaca tggcccatag tgaggataaa aatccaacag ctcaagccat
    21661 tcgccagaga ttccaaggtc aagtagtcta tcctatgctc tctaatcttc ccttctccag
    21721 cgaccgcaag tggggagcca tggagttaga aggtttggga atagttttct taggggcacc
    21781 tgagatgttg ctggattctg aggtcccaga agccagagag gccttggaga gaggttcacg
    21841 tgtcttggtc ttagctctca gtcaggagaa attagaccat cacaaaccac agaaaccatc
    21901 tgatattcag gctctagcct tgctggaaat cttggatcct attcgagagg gagcggcaga
    21961 gacgctgaac tatctccgtt ctcaggaagt ggggctcaag attatctctg gtgacaatcc
    22021 agttacggta tccagcattg cccagaaggc tggttttgcg gactatcaca gctatgtcga
    22081 ttgttcaaaa atcacggatg aggaattgat tgctctggcg gaggagacag cgattttcgg
    22141 acgtgtttcc cctcatcaaa agaaactcat tatccaaacg ctgaaaaaag cgggtcatac
    22201 aacagctatg actggggatg gagttaatga tatcctggct cttcgtgagg cggattgttc
    22261 tatcgtaatg gcggagggag acccggcaac ccgtcagatt gccaacctgg ttctcttgaa
    22321 ctcagacttt aatgatgttc ctgagattct ttttgaaggt cgtcgtgtgg tcaataacat
    22381 tgcccacatc gctccgattt tcttgataaa gaccatctac tcattcttgc tcgcagttat
    22441 ctgtatcgcc agtgctttac taggtcggtc tgaatggatc ttgattttcc ccttcattcc
    22501 aatccagatt accatgattg accagtttgt ggaaggtttc ccaccattcg ttttgacttt
    22561 tgagcgaaat atcaaacctg tcgagccaaa cttcctcaga agatccatgc ttcgtgccct
    22621 accaagtgcc ctcatggtcg tgtttagcgt tctttttgtg aaaatctttg gaacgagtca
    22681 aggttggtct gagttagaaa tctcaactct cctctattat ctcttggggt caattggttt
    22741 cttatccgta tttagagcct gcatgccatt cactctatgg cgagtcctat tgattgtctg
    22801 gtcagtagga ggcttcctag ccacagctct cttcccaaga attcaaaaac tgcttgaaat
    22861 tgcaacctta acagaacaaa cgttgcctgt ttatggtgtc atgatgttgg tctttacagt
    22921 gattttcatc ctgactagtc gctatcaagc tagaaaataa agaaagactg caatctgtgg
    22981 attgcagttt ttttaggtac aagattgcca gccgaaatgt ggtataataa gaggtaatag
    23041 agttttggaa agtgagagaa gatgatttca aagagattag aattggtagc ttcctttgtg
    23101 tcacaggggg ctattttact agatgtggga agtgaccatg cttatctgcc tatcgagttg
    23161 gttgagagag gccaaatcaa aagcgctatt gcaggtgagg tggtggaagg tccctatcag
    23221 tctgcggtta aaaatgttga ggctcacggc ctaaaggaga aaatccaagt ccgtttagcc
    23281 aatggcttgg cagcttttga agagactgac caagtgtctg tcattaccat tgctggcatg
    23341 ggtggtcgtt tgattgctag gattttagaa gaaggtttgg ggaagttagc taatgtagag
    23401 cgtttgatcc tccagcccaa taatcgtgaa gacgacttgc gtatctggct acaggatcat
    23461 ggattccaga ttgtagcaga aagcatctta gaagaagctg gcaagtttta cgagattttg
    23521 gtggtggaag caggacaaat gaagctatca gccagtgatg ttcgctttgg tcccttcttg
    23581 tccaaagaag tcagtccagt atttgtccaa aaatggcaaa aagaagctga gaagctagag
    23641 ttcgccctcg gacaaatccc agaaaaaaat ctggaagaac gtcaagttct agtagataag
    23701 attcaagcta tcaaggaggt gccccatgtt agcgagtgaa gtgatccaag cttatgaagc
    23761 cttttgccct caggaatttt ctatggaggg agacagccgt ggtctgcaaa ttggcacttt
    23821 agacaagggt atccaaaggg tcatggttgc cctcgatatt cgtgaagaga cagtggcaga
    23881 ggccattgaa aagggtgtgg acttgattat cgtcaagcac gcgcctatct ttcgtcctat
    23941 caaggacttg cttgccagcc gtccgcaaaa tcagatttac atcgacctga ttaagcatga
    24001 tatcgcagtt tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc tcaatgactg
    24061 gttttgtcag atgctaggaa tcgaggagac gacttatctg caggaaacag gtccagaacg
    24121 tggaattgga cgtattggga atattcagcc tcagacattt tgggaattgg cccaacaggt
    24181 caagcaagtc tttgacctag atagccttcg aatggtgcat tatcaagaga atgatttgca
    24241 gaagcctatt tcaagagtag caatttgtgg tggaagcggg cagtctttct ataaggatgc
    24301 tttggcaaag ggggcagatg tctatatcac tggcgacatc tactaccata ctgctcagga
    24361 tatgctgtct gatggcttgt tagcattgga tccaggtcac tatatcgaag tgctttttgt
    24421 ggaaaaaatc gcagcactcc ttactcaatg gaaagagaaa aaaggctggg aactagagat
    24481 tttacctagt caagcatcga ccaatccttt ccgtcatatc tagttagaaa gtgaagacaa
    24541 tgaaaaaagt tgccattatt ggagcaggaa ttgtgggagc aacagctgcc tactacctct
    24601 cgagagaaag tgacttagag gtgaccgttt ttgaccatga gcaaggtcaa gccaccaagg
    24661 ccgcagcagg aattatcagt ccttggtttt ccaaacgccg taataaagcc tggtacaaga
    24721 tggcgcgctt gggggctgat ttttatgtgg atttattagc tgatttagag aaatcaggac
    24781 aagaaatcga cttttaccag cgttcgggag tctttctttt gaaaaaggat gaatccaagt
    24841 tggaagaact ttatcaactg gccctccagc gcagagaaga atctcccttg atagggcaat
    24901 tagccattct ggaccaagct tcagctaatg aattattccc tggtttgcag ggatttgacc
    24961 gcctgctcta tgcttctggt ggagcgagag tagatggcca actcttggta actcgtttgc
    25021 tagaagccag tcatgtcaag ctggtcaaag aaaaagtgac tctgacaccg ttagcatcag
    25081 gctaccagat tggcgaagag gtgtttgatc aggttatttt ggcaacggga gcttggttgg
    25141 gggacatgtt agagccttta ggttatgaag tggatgtccg tcctcaaaaa ggacaactac
    25201 gagattatca gcttgcccaa gacatggaag attaccctgt tgtcatgcca gaaggggagt
    25261 gggatttgat tccctttgca ggtgggaaat tatccttggg cgctacccat gaaaatgaca
    25321 tgggatttga tttgacggta gatgaaccct tgctccaaca aatggaggag gccaccttga
    25381 ctcactatct gattttggct gaagctactt caaaatctga gcgtgttgga atccgtgcct
    25441 acaccagtga tttctctcct ttctttgggc aggtgcctga cttaactggt gtctatgcag
    25501 ccagtggact aggttcatca ggcctcacaa ctggtcctat tattggttac catttagctc
    25561 aactgatcca agacaaggag ttgaccttgg accctgaaaa ttacccaatt gaaaactatg
    25621 tcaaacgagt aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact aggaaactag
    25681 ccgcgggtta ctcaaagcac tgctttgagg ttgtggatag aactgacgaa gtcagtaacc
    25741 atacccatgg caaggcgacg ttgacgtggt ttgaattgga ttttcgaaga gtataagcat
    25801 tttactgaaa ttttatcagg tagtttagga tggcaaatga cattccctgt caaaaatggt
    25861 aaaataagaa aaaataatct gagaatcgag gaaaaaagat gcaagaaaag attttggtaa
    25921 ctggtggtgc cggttttatt ggaacccaca ctgttattga attgatccaa gcaggccatc
    25981 aagttgttgt ggtggataat cttgtcaata gcaatcgtaa gagtttagaa gttgttgaaa
    26041 gaatcacagg agttgagatt cctttctatg aggcagatat tcgtgacaca gataccctca
    26101 gagatatttt caagcaggaa gaaccgactg gtgtcattca ctttgctggt ttgaaggctg
    26161 ttggcgaatc aacacgtatc cctcttgcct actatgacaa caatatcgct ggaactgtca
    26221 gccttttgaa agtcatggaa gaaaacaact gtaaaaacat catcttcagt tcttctgcga
    26281 cagtttacgg ggatccgcac acagtgccca tcttggaaga tttcccactt tcagtgacca
    26341 acccatacgg tcgtactaag ctcatgctag aggaaatttt gactgatatt tacaaagcag
    26401 actcagaatg gaatgttgtc ttgcttcgtt actttaaccc aatcggagcc catgagagtg
    26461 gtgatttggg agaaaatcca aacggtattc caaacaatct cttgccatat gtgactcaag
    26521 tagccgttgg aaaattagag caagtgcaag tgtttggaga cgattacgat acggaagatg
    26581 gaacaggtgt tcgtgactat atccacgttg tcgatttggc taagggtcac gttgcagctt
    26641 tgaaaaaaat ccaaaaaggt tcaggactaa acgtttataa ccttggaact ggtaaaggtt
    26701 actcagttct tgaaattatc caaaacatgg aaaaagcggt gggacgtcct attccttacc
    26761 gcatcgtaga acgtcgccca ggtgatatcg ctgcctgcta ctcagatcca gcaaaagcta
    26821 aagcagaact cggttgggaa gcagaactcg acatcaccca aatgtgtgaa gacgcatggc
    26881 gttggcaaag caagcatcca aatggatttg aagactaaga tgatgatttc aatcatcgtc
    26941 ccttgtttaa acgaagagga agtacttcct cttttttatc aggctctgga agctttactt
    27001 ccagatttgg aaacagaaat cgagtatgtc tttgtcgatg atggatcgag tgatgggacc
    27061 ttggaactct taaaggccta tcgggagcaa aatccggcag cccattatat ttctttctcg
    27121 cgaaattttg gcaaagaagc agccctttat gcaggcttgc aatatgcgac aggagatttg
    27181 gtggtggtga tggatgcaga cctccaagat cctcctagta tgttgtttga gatgaaaaat
    27241 gtactagaca aaaatgtaga cttggactgc gttgggacac ggagaactag tcgggaggga
    27301 gaacccttct ttcgcagttt ctgtgctgtt ctcttttatc gcctcatgca aaaaatcagc
    27361 ccagtagctc tgccgtcggg tgtccgtgat tttcgtatga tgagaaggtc tgtggtcgat
    27421 gccattttaa gcttgactga gtccaatcgt ttttcaaagg ggctcttcgc ctgggtgggt
    27481 ttcaaaacct actatttgga ctatccaaat gtcgaaaggc aggctggcaa gaccagttgg
    27541 agttttaggc aactcttttt ctactccatt gaagggatta ttaatttttc agattttccc
    27601 ttgattatag cctttgtagc tggtctccta tcttgttttc tttctctgct gatgaccttt
    27661 tttgttgtgg ttcggaccct cattttgggc aatccgacat ctggttggac ctctctgatg
    27721 gctgttattc tctttcttgg aggcattcaa ctcttgacca ttgggattct cggaaagtat
    27781 atcagtaaga tttatttaga gactaaaaaa agaccacttt atcttatcaa agaaaaaagt
    27841 gaccttcctg attttacaga aaaaaataaa gtgaaaagac tataatttta catggaaata
    27901 tgctaaacta gagggagtgg attatcgcca ttgatttagg cttcctggtt tccaatcagg
    27961 gcgcgagttg ggcaattttt aacagcctct aagacatcct gactaggaga aatttctttt
    28021 tccagttggt cagggtcatc gtaaaaacgc acgattccat tatcgtggta atcaaataaa
    28081 tcagaataag tttggcaaag cccacaggcg atacatcgtt caggtataag tgtgattttc
    28141 atgttcatat ttatattgta ataagaaaag taaaaaaaaa caaggagtaa ggtatggcaa
    28201 aagaaccgtg gcaagaagat atctatgatc aagaagaatc aagagcagag cgtcggcatc
    28261 gaaaccacgg aggggctgat aggatggcta atcgtatttt gacgatccta gctagtattt
    28321 tctttgtaat tgtggtggtg atggtcatcg ttctcatcta tctatcatcg ggggggagta
    28381 atcgcacagc agccttaaaa gactttcatg attctgatgc aagtgtagta caaatctcat
    28441 cttcaagcag ttctcagcct gagcagagtt cagagccaga atctacttct agtagttcag
    28501 aagaagctgc taatcctgaa ggaacgatta aagttctcgc aggagaaggg gaagcagcta
    28561 ttgccgctcg tgcaggaatc tccattgctc agttagaggc cttgaatcct gggcacatgg
    28621 ctacaggatc ttggtttgct aatccaggtg atgttataaa aataaaatag gagccgatat
    28681 gaaaacaatt caaattgcta ttgatggtcc tgcttccagc ggtaagagta cggtcgcaaa
    28741 gattattgct aaggattttg gattcaccta ccttgataca ggagctatgt atcgtgcagc
    28801 gacctatatg gctcttaaga accaattagg agttgaagaa gtcgaagccc ttctagcctt
    28861 gttggaccag catccaatca gctttggacg ttcagaaact ggagaccagc ttgtttttgt
    28921 aggagatgtg gatattaccc atcctatccg tgaaaatgaa gtgaccaatc atgtttctgc
    28981 tattgcagca attcctgaag tgcgtgagaa actggtttct ctccaacaag aaattgccca
    29041 gcaaggcggg attgtcatgg atggtcgcga tattggaact gttgtattgc cacaagcaga
    29101 attgaaaatt ttcctagtag cttctgttga tgagagagca gagcgtcgtt acaaggaaaa
    29161 tattgccaag ggaattgaaa cagaccttga aaccctaaaa aaggaaattg ctgcgcgtga
    29221 ctacaaggat agtcatcgtg agacttctcc tctcaaacaa gcagaggatg ctgtctacct
    29281 tgatacaact ggtttgaaca ttcaagaagt agttgaaaaa atcaaagcag aagctgaaaa
    29341 aagaatgtaa atgtagaaaa gccgatagat tgatatcggt ttttttctaa atttgtcaaa
    29401 atgctgattt tagggtataa tagttgctgt tcgagaaatt ttgattttca aagaatagtg
    29461 aatgatgata aggagaaacc atgaacaatt taccaaattg tccaaaatgt aactcagagt
    29521 atgtctacga agacggtgcc ctactggttt gcccagagtg tgctcatgag tggaatcctg
    29581 ctgaagttgc agaagtagaa gaaggtcttg tcgctatcga tgccaacgga aataaattga
    29641 ctgatggtga tacagtaact ctcatcaagg acttgaaagt aaaaggtgcg ccaaaagatt
    29701 tgaaacaagg gacgcgcgtg aaaaatatcc gcatcgtaga aggcgaccac aatatcgact
    29761 gtaagattga tggttttggt gccatgaaac ttaaatcaga gtttgtgagg aagatttaag
    29821 catgtcaaaa cactataaac ttgtatttta tagccgtatc ttcttgtttc tagcggcttt
    29881 tacgggagtt tatcttgaaa ttactaggca tggtggtttt gggatgcttc tctattacac
    29941 ggttctgtcc aacctcttgg taactatttt taccctttat cttctaaagg ttatgagccg
    30001 tgtaggtgaa aattggcaaa ggccaagtct cttgcgctta aaaggtgggg tcaccatgag
    30061 tatcatgatt acctgtgtga tttaccattt cctcttggcg cccattgcga ctaatttcta
    30121 taccctagaa aatttccttt gccactatat cgttcccatc tggtttttag cggataccct
    30181 cttttttgac aaacagggtc aatacaagat ttgggatcca gcagtgtgga ccattttacc
    30241 ctttctgtat atgatgtttg ctctttttaa tggcttggtt ctaaaactca atattccaaa
    30301 tgccaaggat aatcctttcc cttacttctt tttgaatgtg aacaagggtt ggaatgttgt
    30361 gtttaagtgg tgtctgatta tctttgttgc ctatatggta gcaggattta ttttctactt
    30421 tatcaagcaa atcaagagaa agtcatccta atactcttcg aaaatctctt caaaccacgt
    30481 cagtttccat ctgcaacctc aaaacactgt tttgaacaac ctgcggctag cttcctagtt
    30541 tgctctttga ttttcattga gtataagata caagggattc attttcgaat ttaagaagga
    30601 gtctacaaac caatgaggct tcttcttttc ttgcttattt gataactatc aaaaaagtag
    30661 aagattaaga gaaatataga aagagatttc atgaaacaat ttttagaacg ggccagcatt
    30721 ttggctctct ccctcgtttt gattacctcc ttttccattt cgagtgctct accagccatg
    30781 tttgactatt atcagggtta ttctaaggaa caaattgagc tcttggtgag cttgccttcc
    30841 tttggaatca tgatgatgtt actgctaaat ggtttcttag aaaaaatatt tcctgagcgc
    30901 ttacagatta gtttgggctt gctgatttta tcattgagcg gtacagctcc cttctggtac
    30961 caagcctatc cctttgtctt tggaacacgg cttctctttg gtttgggtct tgggatgatc
    31021 aatgccaagg ccatttctat tatcagtgaa cgctaccaag gaaaaaggcg aattcagatg
    31081 ttagggctac gcgcttctgc agaggtcgtt ggagcttctc tcattacctt ggccgtcggt
    31141 cagttgttgg cctttggttg gacagctatc tttctagcct atagtgctgg atttttggtg
    31201 ctgccccttt atctgctctt tgtcccttat ggaaaatcaa agaaagaagt caagaaaaga
    31261 gcgaaggaag caagtcgttt aactcgagaa atgaaaggct tgatttttac cttagctatc
    31321 gaagcggcag ttgtagtttg taccaataca gctattacca tccgtattcc aagtttgatg
    31381 gtggaaagag gattggggga tgcccagtta tctagttttg ttcttagtat catgcagttg
    31441 atcgggattg tggctggggt gagtttttct ttcttgattt ctatctttaa agagaaactg
    31501 ctcctctggt ctggtattac ctttggcttg gggcaaattg tgattgcctt gtcttcatcc
    31561 ttgtgggtgg tagtagcagg aagtgttctg gctggatttg cctatagtgt agtcttgacg
    31621 acggtctttc aacttgtctc tgaacgaatt ccagctaaac tcctcaatca agcaacttca
    31681 tttgctgtat taggctgtag tttcggagcc tttacgaccc catttgttct aggtgcaatt
    31741 ggcttactaa ctcacaatgg gatgttggtc tttagtatct taggaggttg gttgattgta
    31801 atctctatct ttgtcatgta cctacttcag aagagagctt aggattgatt cctaagtttt
    31861 tcttttgata ctcaatgaaa atcaaagagc atagttgatt gagtttggaa tagtacgctg
    31921 tagttgctaa aatatttcta gaaattaatt tgacttttct aatagagtta ttcatatctt
    31981 atttcaatct actatagaaa gctagccgca ggttgctcaa aatagtgttt tgaggttgca
    32041 gatggaaact gacgtggttt gaagagattt tcgaagagta tgagattttt atacccatac
    32101 aatatttgtt ttaggtcctt gtttacagac taatttcttg ataaaataga ggttatgacg
    32161 agatataaag caactatttc ctatgatggt tatgcctttg ctggctttca gcgccagtct
    32221 catgcgcgta gcgttcagga agaaattgaa aaaaccttga ccagattaaa taaagggcaa
    32281 accattactg ttcacggtgc tggtaggaca gatagtgggg ttcatgccct gggacaggtc
    32341 attcattttg acctgcctta tcagatggat gaggagaaac tccgttttgc cttggatacc
    32401 cagtctcctg aagatattga tgtgatttcg attgagcttg tggcagatga ttttcattgc
    32461 cgttatgcca aacatagcaa gacctatgag tttattttgg atagaggacg tcccaaaaat
    32521 cctatgcgcc gtcactatgc cacccacttt ccctacccac tcgatgtgga acgaatgcag
    32581 attgcaatca aaaagctaga gggaacccat gattttaccg gttttacagc ctctgggact
    32641 agtgtagagg ataaggttcg caccatcaca gaagctagtt taatagtcga tgagacagga
    32701 caatttttga cctttacctt ttcaggaaat ggtttcttgt ataaacagat tcgcaatatg
    32761 gtggggactc ttctcaaaat cggtaacaac cgcatgccag tagagcagat tgatctcatc
    32821 ttggagaaga aggacaggca acttgcaggt cccactgcag caccaaatgg tttgtattta
    32881 aaggagattc gttatgaaga ataatcgtat tttagcactt tctggaaatg atatttttag
    32941 tggtggtgga ctgtcagctg atttggctac ctataccttg aacggcttgc atgggtttgt
    33001 agcagtgact tgtttgacag ccttgacaga aaaaggattt gaagtctttc caactgatga
    33061 taccattttt caacatgaat tagatagctt gcgtgatgtg gaatttgggg gaattaagat
    33121 tggtcttctc cctactgtca gtgtggctga gaaggccttg gactttatca aacaacgccc
    33181 aggagtacct gtggtgttgg atcctgtctt ggtctgcaag gaaacgcatg atgtagctgt
    33241 cagtgagctc tgccaagagt tgattcgctt tttcccttat gtcagtgtga ttacgcctaa
    33301 tctcccagaa gcagaattat tatccggtca ggaaattaaa accttggaag acatgaaaac
    33361 tgcagcgcag aaattgcatg atttaggagc gccagcagtc attatcaagg gaggcaatcg
    33421 tcttagtcag gacaaggctg tggatgtctt ttatgatgga cagaccttta ctatcctaga
    33481 aaatccagtt atccaaggcc aaaatgctgg tgcaggttgt acctttgcct ctagcattgc
    33541 cagtcacttg attaaaggtg ataaactttt gccagcagta gaaagctcta aggctttcgt
    33601 ttatcgtgct attgcacaag cagatcagta tggagtaaga caatatgaag caaacaaaaa
    33661 caactaaaat cgcccttgta tccctattaa ccgccctttc tgtggttcta ggttatttct
    33721 taaaaatccc aacacctaca ggaattctaa ctcttttaga tgctggtgtc ttctttgcgg
    33781 ccttttactt tggtagtcgt gaaggagcgg tagtcggagg actagcaagt ttcttgattg
    33841 acctcttatc aggctaccct cagtggatgt tctttagctt ggtcaaccat ggcttgcagg
    33901 gatttttcgc aggatttaaa ggaaaaagtc agtggttagg ccttatttta gcaactattg
    33961 ccatggtagg aggctacgcc ttgggttcta ctttgatgaa tggctgggca gcagccctcc
    34021 cagaaattct accaaatttc atgcaaaata tggtagggat gattgtagga tttattctta
    34081 gtcaaagtat caagaagatt aagtaatact cttcgaaaat ctcttcaaac cacgtcagct
    34141 tccatctgca acctcaaacc actgttttga gcagcctgag gctagctttc tagtctgatt
    34201 ttcattgagt ataaagaggt tgagtaaaaa gtatttcaaa taagaaaaac gcatagtatc
    34261 aggtgttgaa tgaactgccc cccaaaagtt agacagaaaa aatctaactt ttggggtgtt
    34321 tttattatga aattaagtta tgatgataaa gttcagatct atgaacttag aaaacaagga
    34381 tatagcttag agaagctttc aaataaattt gggataaaca attctaatct taggtatatg
    34441 attaaattga ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa tcgttactat
    34501 tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggctg gactaaagat
    34561 agagtttctc ttgaatacgg tctcccaagt cgtacgatac ttcttaactg gctagcacaa
    34621 tacagaaaaa aacgggtata ctattgttga gaaaacaaga gggagagtac ctaaaatggg
    34681 acgtaagcca caaaagagac ctgaagagag gacagaatta gaacgtcttc aagcagaaaa
    34741 tgagtacctg agagcggaga atgccatcct aaaaaagtta agagaactcc gattgaagga
    34801 ggaaaaagag aaagaagaaa gacagaaatt gttcaagaat taatgactga gttttcgtta
    34861 gatcttcttc taaaagccat taaactagct cgttcgacct actactatca cttgaaacag
    34921 ctagataaac cagataagga ccaagagctt aaagctgaaa ttcaatccat ttttatcgaa
    34981 cacaagggaa attatgctta tcgtcggatt tatttagaac taagaaatcg tggttatctg
    35041 gtaaattata aaagagttca aggcttgatg aaagtactca atttacaagc taaaatgcga
    35101 cagaaacgaa aatggcaaga aggcagagaa tctcattcaa ggccaatttg aaggctctaa
    35161 aacaatggaa aagtgctaca cagatgtgac agaatttgcc attccagcaa gtactcaaaa
    35221 gctttactta tcaccagttt tagatggctt taatagcgaa attatcgcct ataatctttc
    35281 aacttcaccc aacttagaac aagtacaaac aatgttggaa caggcattca cagagaagca
    35341 ctacgagaat acgattctcc atagtgacca aggctggcaa tatcaacacg attcttatca
    35401 tcggttccta gagagtaagg gaattcaagc atctatgtca cgcaagggaa acagccaaga
    35461 caacggtatg atggagtcct tctttgggat tctgaaatcg gaaatgtttt atggctatga
    35521 gaaaacattt aaatcactta atcaattgga acaagctatt gtagactata ttgattacta
    35581 caacaacaaa cgaattaagg taaaactaaa aggacttagt cctgtgcagt acagaactaa
    35641 atccttcgga taaattaatt gtctaactgt ttgggggcag tacattcaac acctgatact
    35701 atgcgtttta ttgtgggaag attttcctca ttttctagtg aaattgaact ttttctaaca
    35761 tcttttgata gatgacttct taatcaatta tcatttccat tgttgtttct tggggtttca
    35821 tcccttgtct ttgataaaag cggagagcac cctcgttatc attccagaca cttagggtta
    35881 gattattgca gccaatttct ttagcataat agcagaaaaa tgacaataaa atagccccta
    35941 gatattttga aaggaaagca taggggctat atagtttaat caaaataaag caaatctttg
    36001 ctggtgcttg taaagaggtc gaagccatcc ttggtaacaa caccgcagtc ttcaatacga
    36061 acaccgactt taccagggat atagatacct ggttcagcag agaagcacat gccttcttcg
    36121 atgaccatgt cgtttccttc catgatagat gggaattcat ggacatccat accgatacca
    36181 tgcccgagac ggtggttgaa gtactcacca taaccagctt tttcgatgac ctcacgggca
    36241 gcgcggtcca cttcatgagc agtcacacct ggcttgataa agtcaagagc agcttgttgg
    36301 gcttcaagag tcaagttgta aatatctttc ttgaattggt ctggtttgcc gacagcgact
    36361 gtacgagtca tatctgacgc atagccattg accagaacac ccaggtcaaa gaggagaaga
    36421 gcatcatttt caaccttatt agctgctgga atgccgtgtg gattcgcagc attatcacca
    36481 gtcaagacca tggtatcaaa gctcatttca taaccttcac gtttcatggc aaagtcgatt
    36541 tgtgcgatga tatctgtctc agtcttatca agagaaatat tgtcaaaacc aacatgaaca
    36601 gccttgtcag cataaagacc tgcaaccatc attttttgca cttcatcagc tgatttgatg
    36661 aggcgcatgc gttggatacg aggagtgagg ttgtcaaact cagcagtctc aaaaactgtt
    36721 ttcaaaccat ggtatttggt caagatgaga ttgtcaaact caacagcgac acgtttgaag
    36781 tcaagttgtg gaagagcatg tttgattttt tgccatggat tttcagaatc gacatagccc
    36841 actactggga aggaaacggt gctacttgca cgttctactt caagagctgg gacaaagagg
    36901 agaggttcct gatccgctag gacaaagagg aacatttggc gttcatgggg atcactgtaa
    36961 aaaccagtga ggtaattgat tgtgacgggg tcagatacga cagcgacgtc tagtttttct
    37021 gattcaagat atgttaggat ttgttgtaat ttagacatat gctaccttct ttctacccct
    37081 ctattttggc aaaaaatgag agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa
    37141 ctccgacaag ataacggagt tctttgatat cattttcctt tgtttaagaa aagtcagcct
    37201 tgcttttgac gtcactgtac tcttcagcga tttcttggct gaggatatcc tcataggcag
    37261 ggagttggat gtcctgacca tatttcttct tgagggcagt agtaactagg cgataagcca
    37321 gattggcatt acgagagagg ataggcccgt ggaagtagga accaaagaca ttcttataat
    37381 gaaccccttc accgaccttt tcttcgttgt ttccatttcc atagacaacc tgtcccagcg
    37441 gtttttggtc atcagagagg aaggtacggc cttggtgatt ttcaaatcca tagtaggttt
    37501 catcgaaatc ttcattgtga atcttgatgt caccgataaa acggttattg gtctggttga
    37561 gcgtgtagtg tcccatgacc cctagccctt cgatacgttt tcctgaagct tcaacataat
    37621 attgacccaa tagttggaaa ccaccgcaga tagccagaac tacaccgtcg ttttggatgt
    37681 agttgtcaat gctctctttt ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt
    37741 cttgaccacc accgaaaaag gcgatgtcgt agtgattttc atcaaagtca tcatggagag
    37801 aaacgatgtc aacggtcaca tgggctccca gtttttcagc cacatacttg agcatgagga
    37861 tgtttccatt gtccccgtag gtattcatga gatttccgta gaggtgggca atgttgagct
    37921 gataggggta attgccatct tttgaggaaa gtgaagtata aaccattagt tcatctcctt
    37981 tctaacaatc tgacgactag ccagcagttc acgaaattcc agcatggcag tataagttgc
    38041 cagaatatag gcatgcttgc agtcttgatt ctcaatggtc ttgagaactt gctccagatt
    38101 actcgtttca gtgattttct cagctggata gccagtcact cggaggcgac gagcgatttc
    38161 agaatgacga acaccgccag cgttgatttc aggaatgtcc atgtcagtga tttgctcaaa
    38221 gtctgcatcc cagatccagc tagtgtcaat tccatctgca tagttggcat taaggaggac
    38281 agataggcta aatggataag gtgctagttt gatcatttcg atagcttggg ttgcaccgac
    38341 tggattttta atcaagacaa gggtacattc cttgtcaccg atatgaaagg tttcttggcg
    38401 tccaaagaca gcacggctct tgtcaaatcc ctgtttgatg agttgcgaat cggcacctag
    38461 gaaacgggcg atggccacag cagctagggc gttatatata ttatagagcc cgccgatttg
    38521 gataccgtat tcttggccgt ctatgacaaa gcgagagcga ttgttggtca actcaaccaa
    38581 ttttgtcaaa cgatagtcga gatcaggacg tttacatcca caaccttcac agatataggc
    38641 acccaagttt gcataggtat tatgctcata tttgaggatg ccttggcagt caggacagag
    38701 aatcccttcg gtattgtagt gagccagttg ggctggtcct ttttccaagt caaaaccaaa
    38761 atactctata gggtttggaa tagttggctt gtagaaaagt ggactgtctc cgttaaggag
    38821 aacagtagca gttggaactt tccgaatggc atccaatatc atgttatagg tagtatagat
    38881 ttcaccgaaa cggtccatct ggtcacggaa gatattagta atgacaaaaa gactaggctg
    38941 gatatagtca cagatacgag atagactggc ttcgtcaatt tcgaggacgg caatattttt
    39001 tccagtttta gaagatttgg ctgttaggaa ggttgttgca atccctgtaa tcatgttggc
    39061 accgcttggg ttggttagaa cttgaccata aacctctttt aaaatgccga cagtgagggc
    39121 agttgtcagg gtttttccat ttgttccagt gacaacgaca atctcgtagt tcttagctag
    39181 gttttgtaaa atatctttat caaattgaag ggcgacttta cctgggagcg tacttccacg
    39241 tccaagacgg cttaaaacga agtgggaaga acgcccagca agaaggccca aagtagtttt
    39301 taagttcatg tttctattat atcacaaaag agggaaaaga cagatttggt gtttcgtaga
    39361 agtaaaaaca gcccaaagag ggctgtcagt taagatgaga tttcaactta aatcgcaaac
    39421 aagtcattca agttctcagc caaggttggg tgagtgaaga tttgttttgt gaagtaagtg
    39481 taaggaatct tgttgtccat agcaacagta atgatgttga tgatttcttg agaaccttct
    39541 gagaagatgc ttgcaccaag aatttctttt gtttcagtat taacaacagc tttgaaagct
    39601 ccgcgaaggt ctccatttac gtgaccacga ggcatggctg caacagggat ttctttcact
    39661 gcgtatggaa gtttcaaatc agctgcttgg ctttcagtca aaccaacttg tgaaagtgca
    39721 ggtgtgatga acatagtatt tggcacattg agacggtcct caagtgtgta gctgccatct
    39781 ccagcaaggt agctgtaaac aacacggaag tcatcaagtg aaatgtaagt aaattgaaga
    39841 ccaccgttga catctccaac tgcaaagaca ccaggaacgt ttgtttgaca gtgtttatct
    39901 actttaatag cgccacgttc agttagttca atatctgtat tttcaagttg aagtggttct
    39961 acatttggtt tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca
    40021 gttacgacaa gcacttggtc accgtcgttt ttaatttcag tagtatggat attttgaagc
    40081 aattcaatac cgtcttcttc catgtattgt ttagcaagag ctgcgatgga aggttctgca
    40141 cgaggtagga atgtatccaa ggcatctagg actgtaacct tgcttcctag tttattgtaa
    40201 aggccagcaa attcaagacc gatatttccg ccaccaagga ctccaagttt ttcaggtaat
    40261 ttgtccaagc tttggatacc tgttgagtca aagatgtttt tgcttgtagc aagtccagga
    40321 attggcaaga cgtttgaaac agcaccagtg ttgatgacga ttgtttcagc agtcagttct
    40381 ttcttttcat caccagcttg gatttcgatg actttatttg aaaggaagtg agcttccgca
    40441 tcaaagatat ctacgcctgt accagcaaca gtcgcatagt ttttaccgtt gaggcgacca
    40501 gtgatcgtgt ttttagtagc aatcacttct tcaaaagaca agtccttttc agcagcaact
    40561 agcaaggttt tagttgggat acaaccaatg ttgatacaag ttccaccgta catagccttg
    40621 ctgcgttcaa cgagggcaac ttttttgcca gctgaagcca atttacctgc tagtgtttta
    40681 ccagctttac caaatccaat aacaattaaa tcgtatgtta acatttatct tcctcctatt
    40741 cgaatttcat tctagcacaa gaaaaaaact tttgcacaat tctgctacgg aaaagacaga
    40801 aaaagataaa aacgctttcc agacaaaaaa ctagtaattt tttgacaagc ttgataaact
    40861 aaaatcctat ctatttttat ataagaaaga ataaatgttc gaaaatagga ggttttatga
    40921 aatcgaatcg ttatattatt gcctttgctg gggtcatttt acacttaatg ctgggttcga
    40981 cttatgcttg gagtgtttat cgtaacccta ttattgaaaa aacgggatgg gatcaggctt
    41041 ctgttgcctt cgcctttagt ctagcaatct tttgtttggg cttatcggct gcatttatgg
    41101 ggcgtttggt agaaaaattt ggtccgaaag tcatggggag tctatctgct tttctatacg
    41161 caggtggaaa tatcttaaca ggatttgcaa tagaccgtca ggaactgtgg ttgttgtatc
    41221 tagcttatgg cattttaggt gggcttggtt tgggagcagg ctatattacc cctgtgtcaa
    41281 cgattataaa atggtttcct gataaacgtg gtctcgcaac aggtttagcg attatggggt
    41341 ttggttttgc ttctttattg actagtccca tagcgcaaca cctcatcgca ggggtaggga
    41401 ttgtagaaac tttttatatt ttaggagcaa gttactttat tatcatgctc ctagcttcac
    41461 aattcattaa gcgtccaaat gagcaagagc ttgcaatttt atcttcttca gggaaagaaa
    41521 aaacagcctc tttgacgcaa ggaatggctg caaatcaggc tctaaaaagc aatcggtttt
    41581 atatgctttg gattattttc tttatcaaca tagcttgtgg tttaggctta atttcagcgg
    41641 catcgccaat ggcacaggag atggctggct tgtctacaag tcatgcagca gtaatggtgg
    41701 gtgttttggg gattttcaat ggatttggtc gcttgctctg ggcgagtttg tctgactata
    41761 tcggtcgccc tctaaccttt agtatattac tgcttgtcaa tcttttcttt tctctctcac
    41821 tttggctctt tacagattcc gttttatttg tagttgctat gtctattttg atgacttgct
    41881 atggagctgg tttttctttg attccagctt atctcagtga tatttttgga accaaggaat
    41941 tggccgctct gcatggttat attttaacag cttgggcaat ggctggttta gcgggaccta
    42001 ttttattagc agagacttat aaaatggctc attcgtacac acaaaccttg ttcgtttttc
    42061 tcattttata cagtatcgcc ttggctttgt cttattatct aggtcgttca atcaaaaaag
    42121 aaagtcaaaa accgcttaca tgattttctg tagaaatggg gctatctttt gctctggtct
    42181 tgtgttatac tagataggtt gcaaagaaaa cagtactttt cttttgtgga aaagaagcaa
    42241 cacgatttta tatctagtta tatgaaaata cgtcataaaa agaaaagtat aaactaagcc
    42301 ctatagggtg gcttcgcacc acctttagaa agaagaataa cgtgaaattt aatgaattaa
    42361 acttgtctgc tgatttgcta gcagaaattg aaaaagctgg ttttgtagaa gctagtccta
    42421 tccaagaaca aactattcct ttggcccttg aaggcaagga tgttattggt caagctcaga
    42481 ctggtacagg aaaaactgca gcctttggct tgcctaccct tgaaaaaatc cgtacagaag
    42541 aagcgactat ccaagctttg gtcatcgctc caactcgtga actagctgtc caaagtcaag
    42601 aagaactctt ccgctttggt cgtagtaagg gagtcaaagt ccgttcagta tatggcggat
    42661 caagcattga aaaacaaatt aaggctctta aatctggtgc ccatatcgtg gtgggaactc
    42721 caggtcgcct cttggacttg attaaacgca aggccttgaa attacaagac attgaaaccc
    42781 ttatccttga cgaagcggat gaaatgctta acatgggctt ccttgaagac atcgaagcca
    42841 ttatttcccg tgtacctgag aaccgtcaaa ctttgctttt ctcagcaact atgccagatg
    42901 ccatcaaacg tatcggtgtt cagtttatga aagcccctga acatgtcaag attgcggcta
    42961 aggaattgac aacagaattg gttgaccagt actatatccg tgttaaggaa caagaaaaat
    43021 ttgacaccat gactcgtctc atggatgtgg cacaaccaga actcgctatt gtatttggtc
    43081 gcaccaaacg ccgtgtggat gaattgactc gtggtttgaa aattcgtggc ttccgtgcag
    43141 aaggaattca tggcgaccta gaccaaaata aacgtcttcg tgtccttcgt gactttaaaa
    43201 atggcaatct tgatgttttg gttgcgacag acgttgcagc gcgtggtttg gatatttcag
    43261 gtgtgaccca tgtctacaac tacgatattc cacaagatcc tgagagttat gttcaccgta
    43321 tcggtcgtac aggtcgtgct ggtaagtcag gtcaatctat tacttttgtt gctccaaacg
    43381 aaatgggtta ccttcaaatc attgaaaact tgactaagaa acgcatgaaa ggtctcaaac
    43441 ctgcaagtgt agaagaatcc ttccaatcaa aaaaacaggt agctctcaag aaaatcgaac
    43501 gtgattttgc agatgaaacc attcgtgcca actttgagaa atttggtaag gatgctcgca
    43561 aattggctgc tgagtttact ccagaagaat tggcaatgta tatcttgagt ctgacagtcc
    43621 aagacccaga tagccttcca gaagtggaga ttgcacgtga aaaaccacta ccgtttaaac
    43681 catcaggtaa tggtttcggt ggtaaagcta agggaggtcg tggaggccgt cgtggggacg
    43741 accgtcgaga gcgtgatcgc cgtggcaatg gtcgccgtga tgagttcaaa aaaggaagtc
    43801 gtggcaacga tcgttttgat aaggaaaaac gttaccgtaa ggataataaa aaaccacgca
    43861 atactttaag cgaaaagcaa acaggctttg ttattcgtaa caagggcgat aaataagaaa
    43921 aagcggttca aaatgaatcg cttttttata taaggagacc gaatgtgaaa agacaaataa
    43981 aattattata ttatctttta taatgttatg atacacaaaa ataggcaact tgtcaataga
    44041 aaaggaacaa tttaattaaa aatattctgg tttttaatta aattgtaagt caatgcaagt
    44101 caataaggaa ttttcagata attattgaaa aagagacgtt tttatgttat aatgatagcg
    44161 attaaattcg aggtgaaaaa tggcacattt attagaaaaa actagaaaaa ttacatcaat
    44221 tttgaaacgc tcagaggagc agttgcagga tgagctccct tacaacgcta ttacgcgtca
    44281 gttagcggat attattcatt gcaatgcctg cattatcaat agtaagggac gtctgcttgg
    44341 ctattttatg cgttataaaa caaatacaga tcgcgtagag caattcttcc aaactaagat
    44401 tttcccagat gactacgttc aaggggctaa tatgatttac gaaacagaag caaacttgcc
    44461 tgttgagcat gatatgagta ttttccctgt tgagagtaga gatgattttc cagatggctt
    44521 gacgactatt gcaccgattc atgtatcggg gattcgcctt ggttctttga ttatttggcg
    44581 taatgataaa aaattcgaag atgaggactt ggttcttgtt gagattgcca gtaccgttgt
    44641 tgggattcag cttcttaact tccaacgtga agaagatgag aaaaatattc gtcgtcgtac
    44701 tgctgtcacc atggcggtca ataccctttc ttactccgaa ctccgtgctg tttcagcaat
    44761 tttaggggaa ttaaatggaa atgaagggaa gttgactgcg tcagtgattg cagatcgtat
    44821 cggaatcact cgctctgtga ttgtcaatgc tcttcgtaaa cttgagtctg cggggattat
    44881 tgaaagtcgc tcacttggaa tgaagggaac ctatcttaag gtcttgattt cagatatttt
    44941 tgaagaagtg aagaaaagag attactaatg acaaaggctt taatttcgat tgattataca
    45001 gaagattttg ttgctgatag tgggaaacta acagcaggtg ctccagctca ggcgatttcg
    45061 gatgccatca gcaaggtaac tcgattagct tttgaacgag gagattatat cttctttact
    45121 attgatgctc atgaagaaaa cgattgtttc catccggaaa gtaagttatt tcctcctcat
    45181 aatctgattg ggacgagtgg acggaattta tatggagatt tggggatctt ttatcaagag
    45241 catggttcag acagtcgtgt cttttggatg gataaacgcc attactcagc tttttcaggg
    45301 actgacctag atattcgttt gagagagcgt agagtgtcta ccgttatctt aacaggtgtc
    45361 ttgacggata tctgtgtcct acatacagct atagatgcct ataatctagg atatgacatc
    45421 gagattgtta aaccagctgt tgcttccatc tggcctgaaa atcatcaatt tgccctaggt
    45481 catttcaaaa atacactcgg agctaagtta gtagatgaaa atctaaatga actttctgag
    45541 taacctggtt ggtgaaaatg aaaaaatttg aaaaaagtgt tgacaagcat cccaaaagtt
    45601 gatatactag taaagtaatc gacgcgggga tggcggaatt ggcagacgcg caggactaag
    45661 gatcctgtga ccgctttagg tcgtgagggt tcaagtccct ctctccgcat aggaaaagag
    45721 ttagctaaag ctagctcttt tgtatttctc taaaaaatta gaatccagtc aaatgtagtg
    45781 gagaatcagc gaaaatatgg gaaaactgat ccttgtttct gcttttgtca tagaagaata
    45841 ataaagatta tcttcttcaa attctccgat attctctaaa gttttgtgca agttgcacag
    45901 aactttttta tttttttggt catcttgcca tagaaaaata aagcgttttc atctataata
    45961 taattatcaa aagacaaaag gagttcacct catggtagaa ttgaatctta aaaatattta
    46021 caaaaaatat ccaaacagcg aacactattc agttgaagat ttcaacttga acatcaaaga
    46081 taaagaattt atcgttttcg taggaccttc aggatgtggt aaatcaacta cactccgtat
    46141 gattgctggt cttgaagaca tcacagaagg tactgcatct atcgatggcg tggttgtcaa
    46201 cgacgtagct ccaaaagacc gtgatatcgc catggtattc caaaactacg ctctttaccc
    46261 acacatgact gtttatgaca acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga
    46321 agacattaac aaacgtgttc aagaagcagc tgaaatactt ggattgaaag aattcttgga
    46381 acgtaaaccg gctgaccttt caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat
    46441 tgtccgtgat gcgaaagtat tcttgatgga cgaacctttg tcaaacttgg atgccaaact
    46501 tcgtgtatca atgcgtgctg aaatcgctaa aattcaccgt cgtatcggag ctacaactat
    46561 ctatgtaact cacgaccaaa cagaagcgat gacacttgca gaccgtatcg ttattatgtc
    46621 agctactaag aaccctgctg gtacaggtac tatcggacgt gtagaacaaa tcggtactcc
    46681 tcaagaagtt tacaaaaatc cagttaacaa attcgttgca ggattcatcg gaagcccagc
    46741 tatgaacttc atcaacgtga aattggttgg tagcgaaatt gtttctgacg gtttccgttt
    46801 gaaagtgcca gaaggagcat tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt
    46861 gatctttggt atccgtccag aagacgtgaa tgcagaacct gctttccttg aaacattccc
    46921 agactgtgtt gtaaaagcga ctatctctgt atcagaactg cttggttcag aatctcacct
    46981 ttactgccaa gttggtaaag acgagtttgt tgcaaaagtt gatgctcgtg actacttgca
    47041 aacaggtgca acagttgagc ttggatttga cttgaacaaa gcacacttct tcgatgtaga
    47101 aactgaaaaa acaatctact aaaataaata aaattcaaag cactacaaga aaagatatct
    47161 ctttatcaat tgtagtggag agatatcagt taatctaggg agagaaacaa aatgcttctc
    47221 tcctttttgc tagggaagtc atattataca tctatattgt gatgctcttt atactcttcg
    47281 aaaatctctt caaaccacgt caacgtcgcc ttgccgtacg tatgattact gacttcgtca
    47341 gttttatctg caacctcaaa gctgtacttt gagtagctta cggctagttt cctagtttgc
    47401 tctttgattt ccattgagta ttatttgtgg gtaccatcta caagtgaagc tatatgcgta
    47461 aactacgtga gcaattgaat tcgaactaga gaggtaataa taaatttatg ctatagttat
    47521 ggtgacttgt atgcttttga ttctagttta tcaaataata gattagaatt gtcagataat
    47581 atcattttgt gtcattttgt gttataatga agaaaaaaca gaggtgttca aatgtcagaa
    47641 gcaggtcata agtttttagc aaaattgggg aaaaaacgct tacgtccagg tggaaagcgt
    47701 gccacagatt ggttaattgc agaaggagga ttttcaaaag aaaagagaat actagaggtt
    47761 gcgtgtaata ggggaactac agcaattgag ttggcacagc gttttggttg caagataact
    47821 gctgttgata tggatgctca agctttagaa gtggctaaaa aatctgctgg aacggcaggt
    47881 gttgctcatt taatcagttt tgaaagagca aatgcaatga aacttcctta tcaagatgct
    47941 agttttgata ttgttataaa tgaagctatg ctgactatgc aagccgatca agctaagaaa
    48001 aaatgtgtaa tggaatatct aagggtatta aaacctggag gtcttctctt gacacatgat
    48061 gtgcttctta aggaagctaa agagtctatc agacaggaat tatcacaagc aattcatgta
    48121 aatgtaggtc ctttaactca agatggttgg gaacaggtga tgatagaatc aggttattgt
    48181 gatgtgaaag tattgactgg tgaaatgaca ttaatgaaat tatcgggtat gatttatgac
    48241 gaaggttggc taggaacttt gaaaatttgt gtaaatgctt gtaaaaagga gaatagaaag
    48301 cagtttttaa ctatgtataa aatgtttgct aagaataaac agaaattggg ctttattgcg
    48361 atggctagtt ataaatcgtc aaaacgttag ataattattg aagttaactt ttcctttttt
    48421 ctttcttaaa aaatatgcta taatagagag taaaaaactt tgaaagaaag aaaaagatga
    48481 atttaaaaga ttacattgca acaattgaaa attatccaaa ggaaggcatt accttccgtg
    48541 atattagtcc tttgatggct gatggaaatg cttatagcta cgctgttcgt gaaatcgttc
    48601 agtatgctac tgacaagaaa gtcgacatga tcgtgggacc tgaagctcgt ggatttatcg
    48661 tgggttgtcc agttgccttt gagttgggaa ttggttttgc tcctgttcgt aagccaggta
    48721 aattgccacg cgaagttatt tctgctgact atgaaaaaga gtacggtgtc gataccttga
    48781 ctatgcacgc ggatgccatt aagccaggtc aacgtgttct tattgtagat gaccttttgg
    48841 cgacaggtgg aactgttaag gcaactatcg agatgattga aaaacttggt ggtgttatgg
    48901 caggttgtgc cttccttgtt gaattggatg aattgaacgg ccgtgaaaaa atcggtgact
    48961 acgactacaa agttcttatg cattattaat gaaaacagtc cctagggctg ttttctctac
    49021 actaggatat aaaaatagac tataactagt tagagaaaaa ctataattga aaactatatc
    49081 ttcttgcagt ataataaaag gactaagtgt ttgagatttg tcttcaaaca catgcaatta
    49141 ttcctgagag agtacagtta ggagagggtt atgccgattc gaattgataa aaaattgcca
    49201 gctgttgaga ttttacggac agagaatatc tttgtcatgg atgatcaacg tgctgcccac
    49261 caagatatcc gtcctttgaa gattttaatt ttaaatctca tgccacagaa aatggtcaca
    49321 gagacccagt tgttgcgcca cttggctaat acacccctac aactggatat tgattttctc
    49381 tatatggaga gccaccgttc taaaacaact cgttcagagc acatggagac cttctataaa
    49441 acttttcctg aagtcaagga tgagtatttt gatgggatga tcatcacggg tgctccagtt
    49501 gagcatttac catttgagga agtggactat tgggaggaat ttagacagat gcttgagtgg
    49561 tctaagactc atgtctattc gacccttcat atctgttggg gagctcaggc tgggctttat
    49621 ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc tatcaggtat ttatcctcag
    49681 gacaccctaa aagagggtca ccttctattt agaggctttg atgatagcta tgtatcccct
    49741 cattcacggc acacggagat ttctaaggaa gaggtcttaa acaagactaa tctcgagatt
    49801 ttatcagaag gacctcaggt tggggtttct attttggcca gtcgtgattt acgagaaatt
    49861 tatagttttg gtcatttgga gtatgaccgt gataccttgg caaaagagta ttttcgagat
    49921 cgtgatgcag gtttcgaccc acatattcca gaaaattact ttaaagatga tgatgttaat
    49981 caggtacctt gtctttgttg gtcttcatct gcagccctct ttttcagtaa ttgggtaaac
    50041 catgcggtct atcaggagac gccttttgac tggagaaaga tagaagatga tgcatctgca
    50101 tatgggtatt tataagagga attatgacat atttagacgc ttttaaatca ggtaccttgg
    50161 ttttaccgag tgccctgctc ttgcatttta aggaactctt tccttctagc gacgattttc
    50221 tggtttggca atttttctat ttgcaaaata cgacaggctt agaagaaatg tcgccaagcc
    50281 agattgctga aaggattggc aaggaaattt cggatgtcaa ccagtccatt tctaatctga
    50341 cggaaagggg actgctccag tatcgtacta tcgaattaaa tggcgaaatt gaattgctct
    50401 ttgatgctag tttggccttg gaacgtttgg atgacctgtt tggagcagtt cattcaagtt
    50461 cagaccagct aacaccacaa aaccagctca aggatttggt ggaaaccttc cagcaggagt
    50521 tgggacgatt gttgacgcct tttgagattg aggatttgac caagacacta aaggaagatg
    50581 gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc tgttttgaat ggaaaaccaa
    50641 actggaagta cattcaggcg attttgagaa actggcgcca tgaaggaatc aagagtgtgg
    50701 ctcaaattga ggccaagaga gcagaaagag aagcaagcaa tcctcagttg acacaggtat
    50761 ctgcagattt cagaaatgcc atggatctct ggaaggatta atccatgcaa gtaggcttga
    50821 aatccgagta agatttgcaa gctgtgtata attgtgatag aataaataga aaataaattg
    50881 aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg ctggtaactg gaaaatgaac
    50941 aaaaatccag aagaagctaa agcattcgtt gaagcagttg catcaaaact tccttcatca
    51001 gatcttgttg aagcaggtat cgctgctcca gctcttgatt tgacaactgt tcttgctgtt
    51061 gcaaaaggct caaaccttaa agttgctgct caaaactgct actttgaaaa tgcaggtgct
    51121 ttcactggtg aaactagccc acaagttttg aaagaaatcg gtactgacta cgttgttatc
    51181 ggtcactcag aacgccgtga ctacttccat gaaactgacg aagatatcaa caaaaaagca
    51241 aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt gtggtgaatc acttgaaact
    51301 tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag tatctgctgc attgtctgga
    51361 ttgactgctg aacaagttgc tgcctcagtt atcgcttatg agccaatctg ggctatcggt
    51421 actggtaaat cagcttcaca agacgatgca caaaaaatgt gtaaagttgt tcgtgacgtt
    51481 gtagctgctg actttggtca agaagtcgca gacaaagttc gtgttcaata cggtggttct
    51541 gttaaacctg aaaatgttgc ttcatatatg gcttgcccag acgttgacgg tgcccttgta
    51601 ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc ttgactttgt aaaataatca
    51661 gtaagtagca aaagctaggt ggaacagcat tcagatgtct gttacatttt ttataggaga
    51721 ggaaagattg aaaataaaaa ttggattagc aagtatctgt ttactaggct tggcaactag
    51781 tcatgtcgct gcaaatgaaa ctgaagtagc aaaaacttcg caggatacaa cgacagcttc
    51841 aagtagttca gagcaaaatc agtcttctaa taaaacgcaa acgagcgcag aagtacagac
    51901 taatgctgct gcccactggg atggggatta ttatgtaaag gatgatggtt ctaaagctca
    51961 aagtgaatgg atttttgaca actactataa ggcttggttt tatattaatt cagatggtcg
    52021 ttactcgcag aatgaatggc atggaaatta ctacctgaaa tcaggtggat atatggccca
    52081 aaacgagtgg atctatgaca gtaattacaa gagttggttt tatctcaagt cagatggggc
    52141 ttatgctcat caagaatggc aattgattgg aaataagtgg tactacttca agaagtgggg
    52201 ttacatggct aaaagccaat ggcaaggaag ttatttcttg aatggtcaag gagctatgat
    52261 gcaaaatgaa tggctctatg atccagccta ttctgcttat ttttatctaa aatccgatgg
    52321 aacttatgct aaccaagagt ggcaaaaagt gggcggcaaa tggtactatc tcaagaagtg
    52381 gggctatatg gctcggaatg agtggcaagg caactactat ttgactggaa gtggtgctat
    52441 ggcgactgac gaagtgatta tggatggtgc tcgctatatc tttgcggcct ctggtgagct
    52501 caaagaaaag aaagatttga atgtcggctg ggttcacaga gatggtaaac gctatttctt
    52561 taataataga gaagaacaag tgggaaccga acatgctaag aaagtcattg atattagtga
    52621 gcacaatggt cgtatcaatg attggaaaaa ggttattgat gagaacgaag tggatggtgt
    52681 cattgttcgt ctaggttata gcggtaaaga agacaaggaa ttggcgcata acattaagga
    52741 gttaaaccgt ctgggaattc cttatggtgt ctatctctat acctatgctg aaaatgagac
    52801 cgatgctgag agtgacgcta aacagaccat tgaacttata aagaaataca atatgaacct
    52861 gtcttaccct atctattatg atgttgagaa ttgggaatat gtaaataaga gcaagagagc
    52921 tccaagtgat acaggcactt gggttaaaat catcaacaag tacatggaca cgatgaagca
    52981 ggcgggttat caaaatgtgt atgtctatag ctatcgtagt ttattacaga cgcgtttaaa
    53041 acacccagat attttaaaac atgtaaactg ggtagcggcc tatacgaatg ctttagaatg
    53101 ggaaaaccct cattattcag gaaaaaaagg ttggcaatat acctcttctg aatacatgaa
    53161 aggaatccaa gggcgcgtag atgtcagcgt ttggtattaa gcgatgattt gaaagaggga
    53221 tgtgatagta gcaccctctt tttctttgtt ttatgatagt tcatcctcga gtaaattcaa
    53281 gttcttgctc ggaaatgaag cttatatagt agattgaata tagacaaata ccttgtgatt
    53341 ggtaaaacat tttagaaatt catttacctt tcctaatcga cttggtttca tcttatttca
    53401 atctattata gtattgggga atttcttcaa accacatcag cttggtcagt cctacctgcg
    53461 acctcaaaac ttgtgctttg gtcaagctgg gtttagtttc ctagtttgct gatggatttc
    53521 cattgactat aagcatccaa ccctcttttt tgtcttctaa agaattctta aattatcagt
    53581 ctattgcaac ttttctcata taagttcttt gtcttgctat tggttttcct tagtagtata
    53641 ctaaggtagt aatcattaag aagtggttac aaaaaataat gaatgaggta aagaaaatgg
    53701 tagaattgaa aaaagaagca gtaaaagacg taacatcatt gacaaaagca gcgccagtag
    53761 cattggcaaa aacaaaggaa gtcttgaacc aagctgttgc tgatttgtat gtagctcacg
    53821 ttgctttgca ccaagtgcac tggtatatgc atggtcgtgg tttccttgta tggcatccaa
    53881 aaatggatga gtacatggaa gctcttgacg gtcaattgga tgaaatcagc gaacgcttga
    53941 ttacactcgg tggaagccca ttctctacat tgacagagtt ccttcaaaat agtgaaatcg
    54001 aagaagaagc tggtgaatac cgtaatgttg aagaaagctt ggaacgtgtt cttgttatct
    54061 accgttactt gtcagaactt ttccaaaaag gtttggatgt cactgatgaa gaaggtgacg
    54121 atgtgacaaa cggtatcttt gcaggcgcta aaactgaaac agataaaaca atttggatgc
    54181 ttgcagccga acttggacaa gcacctggtt tgtaagaaat aaggaaacat agataaatct
    54241 gtaggaaatt tcttacagat tttttctatt ttgtaagcta ttccaaacca gtcttttttt
    54301 gagttttttg ataaaatagt actatcagtg aaaaggatgg aagcatgact aagaaaatcg
    54361 tagctatttg ggcccaggat gaagagggtg tgattggtaa ggacaatcgt ctgccttggc
    54421 atttgccagc agaattgcag cactttaaag aaacaactct gaatcatgct atcttgatgg
    54481 ggcgtgtgac ctttgatggg atggggcgtc gcttgcttcc aaaacgggaa accctgattt
    54541 tgacgcgtaa tccggaagaa aagatagatg gggttgctac ttttcaggac gtccagtctg
    54601 ttcttgactg gtatcaggct caagaaaaga atctctacat tatcggtggg aagcaaattt
    54661 ttcaggcttt tgaaccttac cttgatgaag tgattgtcac tcacattcat gctcgggtgg
    54721 aaggagatac ctatttccct gaagaacttg acttgtctct ttttgagaca gtttcaagca
    54781 aattttacgc caaagatgag aagaatcctt atgattttac catccaatac cgcaagagaa
    54841 aggaagtcta atggaacgga gtttatttgg tctattcacg gcttttctgt gtttcatctg
    54901 ctttctggca ggagcacaag cttttcgtaa aaagcgttac gggctttcta tcctcctttg
    54961 gttaaatgcc tttaccaatc tggtcaatag tattcatgct ttttacatga ccttatttta
    55021 gatagaatga cagtatagaa tggaaggaaa tcatgtctac aaatagaaaa aatgatatga
    55081 tggtttattg ctcattttgt ggcaaaaacc aagaagaagt acaaaaaata attgctggca
    55141 acaatgcttt tatttgtaat gaatgcgtgg agttagctca ggaaatcatt cgagaagaat
    55201 tggttgagga agtcttggca gacttgtctg aggtgccaaa accaattgaa ctcctccata
    55261 tcttgaacca ctatgtaatt ggccaagatc gtgccaagcg tgccttggca gtggcggttt
    55321 ataaccacta caaacgcatc aatttccacg atacacgcga agagtcagaa gatgtggatt
    55381 tgcagaagtc aaacattttg atgattggcc caactggttc agggaaaact ttccttgccc
    55441 agaccttggc taagagcttg aatgtacctt ttgctattgc ggatgcgaca gctctgacgg
    55501 aggctggtta tgtgggtgag gatgtggaaa atatcctcct caaactcttg caggttgctg
    55561 actttaacat cgaacgtgca gagcgtggca ttatctatgt ggatgaaatt gacaagattg
    55621 ccaagaagag tgagaatgtg tctatcacac gtgatgtttc tggtgaaggg gtgcaacaag
    55681 cccttctcaa gattatcgag ggaactgttg ctagcgtacc gcctcaaggt ggacgcaaac
    55741 atccacaaca agagatgatt caagtggata caaaaaatat cctcttcatc gtgggtggtg
    55801 cttttgatgg tattgaagaa attgtcaaac aacgtctggg tgaaaaagtc atcggatttg
    55861 gtcaaaataa taaggcgatt gacgaaaaca gctcatatat gcaagaaatc atcgctgaag
    55921 acattcaaaa atttggtatt atccctgagt tgattggacg cttgcctgtt tttgcggctc
    55981 ttgagcaatt gaccgttgat gacttggttc gcatcttgaa agagccaaga aatgccttgg
    56041 tgaaacaata ccaaactttg ctttcttatg atgatgttga gttggaattt gacgacgaag
    56101 cccttcaaga gattgctaat aaagcaatcg aacggaagac aggggcgcgt ggacttcgct
    56161 ccattatcga agaaaccatg ctagatgtta tgtttgaggt gccgagtcag gaaaatgtga
    56221 aattggttcg catcactaaa gaaactgtcg atggaacgga taaaccgatc ctagaaacag
    56281 cctagaggtg actatggaac ttaatacaca caatgctgaa atcttgctca gtgcagctaa
    56341 taagtcccac tatccgcagg atgaactgcc agagattgcc ctagcagggc gttcaaatgt
    56401 tggtaaatcc agctttatca acactatgtt gaaccgtaag aatctcgctc gtacatcagg
    56461 aaaacctggt aaaacccagc tcctgaactt ttttaacatt gatgacaaga tgcgctttgt
    56521 ggatgtgcct ggttatggct atgctcgtgt ttctaaaaag gaacgtgaaa agtgggggtg
    56581 catgattgag gagtacttaa cgactcggga aaatctccgt gcggttgtca gtctagttga
    56641 ccttcgtcat gacccgtcag cagatgatgt gcagatgtac gaatttctca agtattatga
    56701 gattccagtc atcattgtgg cgaccaaggc ggacaagatt cctcgtggta aatggaacaa
    56761 gcatgaatca gcaatcaaaa agaaattaaa ctttgaccca agtgacgatt tcattctctt
    56821 ttcatctgtc agcaaggcag ggatggatga ggcttgggat gcaatcttag aaaaattgtg
    56881 aggaaaagaa aatggcaaaa acaattcata cagataaggc cccaaaggct atcggaccct
    56941 atgttcaagg aaaaatcgtt ggcaaccttt tgtttgctag cggtcaagtt cccctatccc
    57001 ctgaaactgg ggaaattgta ggagagaata tccaagaaca gacagagcaa gtcttgaaaa
    57061 acatcggtgc tattttggca gaagcaggaa cagactttga ccatgttgtc aaaacaactt
    57121 gcttcttgag cgatatgaac gactttgttc cttttaatga ggtttaccaa acggccttca
    57181 aagaggaatt cccagctcgt tcagctgtgg aggtagctcg tcttcctcgt gatgtaaaag
    57241 tcgaaattga agtcatcgca gagattggat aagctagttg aagtttggtg ttgccaaact
    57301 tcttttgata taaggagaaa aagatgacaa agaaacaact tcacttggtg attgtgacag
    57361 ggatgagtgg cgcagggaaa actgtagcca ttcagtcctt cgaggatcta ggttatttca
    57421 ccattgataa tatgccgcca gctctcttgc ctaagttttt gcagctggtt gaaattaagg
    57481 aagataatcc taagttggct ttggtagtgg atatgcgtag ccgttctttc ttttcagaga
    57541 ttcaagctgt tttggatgag ttggaaaatc aagatggttt ggatttcaaa atcctctttt
    57601 tggatgcggc tgataaggaa ttggtcgctc gttacaagga aaccagacgg agtcacccac
    57661 tagcagcaga cggtcgtatt ttagatggaa tcaagttgga acgtgaactc ttggcacctt
    57721 tgaaaaatat gagccaaaat gtggtggata cgactgaact cactccacgt gaactgcgca
    57781 aaacccttgc agagcagttt tcagaccaag aacaagccca gtctttccgt atcgaagtca
    57841 tgtctttcgg atttaagtat ggaatcccga ttgatgcgga cttggtcttt gatgtccgtt
    57901 tcttgccaaa tccctattat ctaccagaac tgagaaacca aacgggtgtg gatgaacctg
    57961 tttatgatta tgtcatgaac catcctgagt cagaagactt ttatcaacat ttattggcct
    58021 tgattgagcc gattctgcca agttaccaaa aggaaggtaa gtccgttttg accattgcta
    58081 tgggatgtac gggtggacaa caccgtagtg tggcatttgc taaacgcttg gcgcaggact
    58141 tatccaagaa ttggtctgtt aatgaagggc atcgcgacaa agaccgcaga aaggaaacgg
    58201 taaaccgttc atgagaaaac caaagataac agtgattggt ggagggactg gaattcccgt
    58261 cattctaaaa agtctgcggg aaaaagatgt ggaaatcgca gctatcgtga cggtggcaga
    58321 tgatggtggt tcttcaggtg aactccgaaa aaatatgcaa cagttgacac cgccaggtga
    58381 tcttcgtaat gtccttgtgg ccatgtcgga tatgcctaag ttttatgaga aggtctttca
    58441 gtatcggttc tctgaggatg ccggagcctt tgctagccat ccattgggaa atctcatcat
    58501 tgctggcttg tcagaaatgc agggttcaac ctataatgcc atgcagttat tgagcaaatt
    58561 tttccataca acagggaaaa tttatccttc cagtgaccat cctttgaccc ttcatgcagt
    58621 ctttcaggat gggacagaag tggctggaga gagtcatatt gtagaccatc gaggcataat
    58681 tgacaatgtc tatgtgacca atgccctaaa cgatgatacg cctctggcca gccgtcgagt
    58741 agtgcaggcc atccttgaaa gtgacatgat tgtcctaggg ccaggttccc tctttacctc
    58801 tattttgccc aatatcgtga ttaaggaaat tgggcgggct cttttggaaa ctaaggcaga
    58861 aattgcctat gtctgtaata tcatgaccca acgtggggag acggaacact ttacagatag
    58921 cgaccacgtg gaagtcttgc atcgtcacct tggtcgccct tttatcgaca ctgtcttggt
    58981 gaatattgaa aaagtgcctc aggaatacat gaattccaac cgttttgatg aatacttagt
    59041 gcaagtggaa cacgattttg taggtctttg taagcaagtt tcgcgcgtga tttcatctaa
    59101 cttccttcgt ctggaaaatg gcggtgcctt ccacgatgga gatttgattg tggacgagtt
    59161 gatgcgcatt atacaggtga aaaaatgagt ttcacagtag cagtaaaaga agaaatcctg
    59221 ggccaacacc atctgagctg gcatgaatta tctgccatta tcaaaatgtc tggtagcatc
    59281 ggtctctcga cttcgggctt gactttgtca gttgtgacag aaaatgccaa actggcccgt
    59341 cacctctatg agtcctttct tcatttctat gaaatcaaat ctgaaattcg tcaccaccaa
    59401 cgtagcaatc ttcgcaagaa tcgcgtctat accgttttta cagatgaaaa ggtgcaggat
    59461 ttgttaagtg atttgcactt ggcagactct ttctttggcc tggaaacagg tattgatgag
    59521 gcgattttat cggatgagga agcaggtcgt gcctatctct gtggcgcttt cttggcaaat
    59581 gggagcattc gtgaccctga gtcaggcaag taccagttgg aaatcagttc tgtttatctg
    59641 gaccacgcgc aaggaattgc ctcccttctc caacagtttt tactggatgc caaggtgctt
    59701 gagcgcaaga agggggctgt gacctatctc cagcgagcag aagacattat ggacttcttg
    59761 atagtaatcg gagccatgca ggcacgtgat gattttgagc gggttaagat tttgcgagaa
    59821 acccgtaacg acctcaatcg ggctaataat gccgagacag ctaatatcgc tcggacagtt
    59881 tctgccagca tgaagaccat taacaatatc agtaaaatca aagatatcat gggcttagaa
    59941 aatttgccag tagatttgca ggaagtggcg caactgagga ttcagcaccc agactactct
    60001 atccagcagt tagcagatag tctcagcacc cctctgacca aaagtggtgt caatcacaga
    60061 ctcagaaaaa tcaataagat agccgatgaa ttataaaacc acgaatccta tgtgactcgt
    60121 ggttcttttt tataaactgg tagagtgttt tggttgtact ttttgttcag ggtcaatgta
    60181 gttgatagcg ttgttgacag cagttggagc ttctccgagg cctgtcgcaa tcagatcaat
    60241 ttttccgtca tagtagcagc agtcaccgat agcatagata cctgcttggc tggattcttg
    60301 tttgctgttg acgataatct tgtgacggtt gaggtcgagc ccccagtttt taaggttacc
    60361 gacagaagat ttgaaaccat agttgacaaa gaggtggtct aggtcaatgg tttcagtttc
    60421 atcagatttg acttttgtga tttcaagttt atcaagtgtt tttccatttc caaggagttg
    60481 gccaggggcg aatggtgtct tgatggttac agatgattct tgcaaggctt gaacactgtg
    60541 ttccaaggca cggaaattat ctctgcggtg aacaagggta gttggtgcga ttttttcaaa
    60601 agccaaagcc caatccacag ccgagtctcc cccaccaaga atcgtcactt tcttaccagc
    60661 gtattgctga atgttagaaa cgtggtagtg gatattttca tagccctcaa ccccttcaag
    60721 ttccagcgga cgtggtttga aggcaccgcc acccatagcg atgataactg ttttagtcag
    60781 gtgacttcct ttagaagttg tgatggcaaa ttcttcttgt ttgtcaatct caagaaccgt
    60841 ttcattgaga tgaatagggg tatcaaatcc atttagctgt tcaatcaagc ggttagtcaa
    60901 ctcttctcca gtcaggtttg ggaagcctgg tacgtctagg atttcctttt cagggtagag
    60961 aatagcaggt tgtccaccta gctggggaag agagtcgatg atttgaacct tggcttggcg
    61021 taggtgggca taaaaggctg caaaaagccc gacaggacca ccacccacaa tggtaatatc
    61081 atagagttga gacatagttt ctcctttgtt ttttctagtc agtttatttt atcatatttt
    61141 tgttcaatgt aaaatggact aggataggga aaaaaatgcc cgaaaatggt ataataggac
    61201 gaaagtgttt tgatagggag gatatcaggg atgaattttc aacaattatc caatctgcaa
    61261 tattggacca gtttgtttgc aagtccatgg acgatagcta tcaatctgat tgatattttg
    61321 attgttgctt atattttata ccattttaca aaagctattg caggaaccaa gattatgatt
    61381 ttggtacgtg gagttttggt atttatttta gctcaaatcc ttgcaaatat gattggtttg
    61441 actacgattt cttggttaat caatcaaatt attacttatg gggttattgc ggcggttgtt
    61501 atcttctctc cagagattcg gactggtttg gaacgtttgg gaagagcgac agatttcttt
    61561 tccaatgccc ctattagtgc tgaggaacag atgattcgtg cctttgttaa gtctgttgaa
    61621 tacatgagtc ctcgtaaaat cggggccttg gttgctattc agcgtgtacg taccttgcag
    61681 gagtatattt cgacaggaat tcccttggat gctaagattt ctgcagaact tctcattaac
    61741 atttttattc ccaacactcc cctacatgac ggtgcggtga ttatcaaaga agaacgtatc
    61801 gctgtgacgt ctgcctatct gcccttgaca aaaaacacag ggatttccaa ggaatttggg
    61861 accagacacc gggcggctat cggtttatca gaagtctcag atgccttgac ttttgtcgta
    61921 tcagaggaaa cgggaggaat ttcgataacc tataatggaa ggtttaagca caacctaaca
    61981 cttgatgaat ttgaaacaga attacgtgaa atcttacttc caaaagagga agtgggtctt
    62041 agttttaaag aacgattgct aggaggatgg aaacatgaaa aaaaatagtt tatatatcat
    62101 atcctcactc ttttttgctt gtgtcttatt tgtctatgct acggcgacga attttcaaaa
    62161 cagtaccagt gctaggcagg taaaaacgga aacctatact aatacagtaa caaatgtccc
    62221 tattgacata cgctataata gtgataagta ttttattagc ggttttgctt cagaagtatc
    62281 agtggtcttg actggtgcaa atcgcctatc gctagctagt gaaatgcaag aaagtacacg
    62341 taaattcaag gttactgctg acctaacaga tgccggtgtt ggaacgattg aagttccttt
    62401 gagcattgaa gatttaccca atgggctgac cgctgtggcg actccgcaaa aaattacagt
    62461 caagattggt aagaaggctc agaaggataa ggtaaagatt gtaccagaga ttgaccctag
    62521 tcaaattgat agtcgggtgc aaattgaaaa tgtcatggtg tcagataaag aagtgtcgat
    62581 tacgagtgac caagagacat tggatagaat tgataagatt atcgctgtct tgccaactag
    62641 cgaacgtata acaggtaatt acagtggttc agtacctttg caggcaatcg accgcaatgg
    62701 tgttgtctta ccggcagtta tcactccgtt tgatacaata atgaaggtga ctacaaaacc
    62761 agtagcacca agttcaagca catcaaattc aagtacaagc agttcatcgg agacatcttc
    62821 gtcaacgaaa gcaactagtt caaaaacgaa ttaaaaatag aaaaggattt tataacaatg
    62881 ggtaaatatt ttgggactga tggagtccgt ggagaagcta acctagaact aacaccagaa
    62941 ttagccttta aactaggacg ttttggaggc tatgttctta gtcaacatga aacggaagcg
    63001 ccgaaagtct ttgtaggacg tgacacacgt atttcagggg aaatgctgga atcggccttg
    63061 gtggcaggtc tcctttcagt agggattcac gtatacaaac ttggtgtcct tgcaacacca
    63121 gcagtagctt acttggttga aactgaagga gcaagtgccg gtgtcatgat ttctgctagc
    63181 cacaacccag cccttgataa cggaatcaag ttctttggcg gtgatggctt caaactagat
    63241 gatgaaaaag aagcagaaat tgaagccttg ctagatgctg aggaagacac tcttcctcgt
    63301 ccaagtgcag aaggcttagg aattttggta gattatccag aaggcttgcg taagtatgaa
    63361 ggataccttg tttcaactgg aactcctctt gatggaatga aggttgcctt ggatacagct
    63421 aatggagcag cttctaccag tgcccgtcaa atctttgcag accttggtgc ccaattgacg
    63481 gttatcgggg aaacaccaga cggtcttaac atcaacctta atgttggttc aacacatcca
    63541 gaagcccttc aagaagtggt caaagaaagt gggtcagcta ttggtttggc ctttgatgga
    63601 gacagtgacc gcttgattgc tgttgatgag aatggtgaca tcgtcgatgg tgacaagatt
    63661 atgtatatca tcggaaaata cctttctgaa aaaggacaat tggctcaaaa tacaattgtg
    63721 acaactgtta tgtctaacct tggtttccac aaggccttga atcgcgaagg tattaacaag
    63781 gcagttactg cagttggtga ccgctacgtt gttgaagaaa tgagaaaatc aggctacaac
    63841 cttggtggtg aacagtctgg tcacgttatc ttgatggatt acaataccac aggtgatggt
    63901 caattatcag cagttcaatt gactaaaatc atgaaggaaa ctggtaagag cttatcagag
    63961 ttggcggcag aagtaacgat ttatccacaa aaattagtta atatccgagt ggaaaacgtc
    64021 atgaaggaaa aggccatgga agtgccagct atcaaggcca tcatcgagaa gatggaagaa
    64081 gaaatggcgg ggaacggccg tatccttgtt cgtccaagtg gaacagaacc cctcttgcgt
    64141 gttatggcag aagcgcctac aacagaagaa gtagactact atgttgatac catcacagat
    64201 gtagttcgtg ctgaaattgg gattgactaa atcctagaaa actagatgaa aataaaaaat
    64261 tatggtacaa tagcttataa tattgtagcc gatggagaaa gacatgaatc ttaaacgtga
    64321 acaagaattt gttagtcagt atcattttga tgcgcgtaat tttgaatggg aaaatgaaaa
    64381 tggagctcct gaaaccaagg tggatgtgaa tttccaattg ctccaacatg accaagaaaa
    64441 tcaagtgact tccttgattg tcatcttgag ctttatgatt gtatttgata agtttgtcat
    64501 tagtggaaca atctcacaag taaaccatat cgatggccgt attgtcaatg aaccaagtga
    64561 attgaaccaa gaagaggtgg aaaccttggc tcgtccatgt ttgaacatgc tcaatcgttt
    64621 gacttacgaa gtgactgaaa ttgcattaga cttaccagga attaatttgg agttctaata
    64681 tgaaattagc tgttttcaca gattcctctg cttatctcag tgaagagacc ttgcaaagag
    64741 aagacttgtt tgtcttggat attcctgtca atattgatgg tgaggaatat gtcgaaggca
    64801 tcaatctgtc tgctgaggaa ttttaccaaa aaatggctca ggcttctgaa ttgcctaaga
    64861 ccagtcaacc aagtattgcc aagttagatg agatcttaac ttcgctcaaa gaacaaggct
    64921 atacacatgc cttggggctt ttcctatctt ctggaatttc aggtttttac caaaatatcc
    64981 agtatatggt cgatgactat gagggcttaa ccattgcttt cccagacact ttgattacaa
    65041 gtgctcccct aggcatcatg gttgaaagcg tctttaattg gcgtgatcag ggcgatgatt
    65101 ttgccagcat tcaggataag ctagccattc aaatcagccg tacgtcagcc tttatcatgg
    65161 tagatgactt ggatcatttg gtaaaaggtg gacgcctttc aaatggggct gccattttgg
    65221 gcaatttgct tagcattaag ccaatccttt attttaacga tcaaggtgtg attgaagttt
    65281 acgaaaaagt tcgtactgaa aagaaggcca ccaaacgctt aattgaaatt atcaaggaaa
    65341 caacggcttc aggtcaatac cgggtcattg tcattcatgg gaatgctcct gaaaaggctg
    65401 aagaattgcg tcagcatttg cttgattttg gcttgggttc ggatgtttca cttgctacat
    65461 ttggtagtgt cattggaacg cacctaggag caggaagtat tgctctgggt tatattccag
    65521 tgatttagta ggcacttcta ggctagttaa tcttagcaat tgaacacgga ctacctgcct
    65581 cttgaaaaaa gatgtctgtc ttgcctttcg tggaaagtca gtgccattcc ctatttttca
    65641 tgggtggcta agatcctttg tattttgata attgaacacg cctggaaccc tgtgtgaaaa
    65701 agatagttct tccaaggagt agacacttct tgatcagaat tcctattttc actttgtgtt
    65761 cttacaggct ttgtatctta gacaggagta gagatgagta ttcgagtaat tattgccggt
    65821 tttaagggaa agatgggtca agctgcttgc cagatggtct tgcctgattc agatttggac
    65881 ttggtagcag ttttggatcc ttttgagtct gagtcagaat ggcagggtat tcctgttttc
    65941 aaggataagg ctgatttagc tggttttgaa gcggatgtct gggtagactt tactactcca
    66001 gctgttgcct acgaaaatac acgttttgct cttgaaaatg gctttgctcc agtagttgga
    66061 acgactggtt tcacgagtga agaaattgca gagctaaaag aattttctcg tgcccaagac
    66121 ttgggtggcc tgattgcccc taactttgcc ttgggtgctg tcttactcat gcaatttgcg
    66181 acgcaggctg ccaaatattt cccaaatgtg gagattattg agctccatca tgacaagaaa
    66241 aaggatgctc cgagtggaac agccattaaa acagctgagt tgatggcaga ggttcgagag
    66301 tccattcagc aaggtgcagc agatgaggaa gagctgattg ctggtgctcg tggtgctgac
    66361 tttgatggta tgcgcatcca ctcagttcgt ttgccaggct tggtagctca tcaggaagtc
    66421 atctttggca atcagggaga agggttgacc ctccgtcatg actcctatga tcgcatctcc
    66481 ttcatgacag gagtcaattt gggaattaaa gaagttgtca agcgtcatga gcttgtctat
    66541 ggattagaac acttattatg agattaacgc aaatgccttc tgaatttcag aaggctttac
    66601 cagtattaga aaaaattaaa gaagcaggct ttgaggctta ttttgttggg ggctctgttc
    66661 gagatgccct tctccatagc cctatccacg atgtggatat tgcgacgtct tcttatccag
    66721 aagagaccaa gcagattttt ccgcgaacag ccgatatcgg aatcgagcat ggaaccgtat
    66781 tggtcttaga tggggatgag gagtatgagg taacaacctt tcggacagag gatgtctatg
    66841 tggactatcg cagacccagt gcggtttcct ttgtacgatc gctagaagaa gacctcaaac
    66901 gccgtgattt cacagtcaac gcctttgcct tggatgagac aggagaaatc gttgacttgt
    66961 tccatggttt agaagatttg gaaaagcaag tcttgcgagc agttggagtg gctagtgagc
    67021 gtttcaacga agatgcttta cggattatgc gtggtttccg ttttcaggct agtcttggtt
    67081 ttgcacttga gccagaaaca tttaaagcta tgaagacctt gacgccgctt ttggagaaaa
    67141 tttctgtaga gcgtaccttc gtcgagtttg ataaactctt gctggctcca ttttggagaa
    67201 ggggcttggc ttccatgatt gagagtcaag cttatgacta tctccctgat atggcatcta
    67261 gccaggacaa gctcaacaga ctgtttgatt tggagactga ttttactttt gaatcctctg
    67321 aacaagcctg ggcggcttta ctatgggctt tggagattga aaatgcgcag tcatttttga
    67381 aatcttggaa gacctcacgc cagtttgcca agcaagttca ggatttgctg attattttgg
    67441 ctctgcgtga aaatggagaa ttgagcaagc gagattgtta tcgctttgac atagatttgc
    67501 ttttacaggc tgaaaatctt cgtcaagctc gaggaaaaga agtcaaccca caagccatca
    67561 cagaaaaata ccaaagcttg actatccatg acaagaaaga gattcagatt aatggcgata
    67621 ttttgatcaa ggaatatggc tatcagccag gcccagactt gggagagatt ttaacagaga
    67681 ttgagtttgc cattgtcgat ggagaattgg agaataatcg tgaagccatc catgcttacc
    67741 tgagggagaa aaaatgagtg attttatcgt tgaaaaacta agtaaatccg ttggtgacaa
    67801 gaccgttttt agggatattt cctttattat ccatgactta gacagaattg gtttaatcgg
    67861 tgtcaatggg actggcaaga ccaccctttt ggacgtcctt tctggtgttt ctggatttga
    67921 tggggatgtc agtccttttt cagctaaaaa tgattaccag attggttact tgactcagga
    67981 tcctgatttt gatgatagaa agacagtttt ggatacggtt ctatctagtg aactcaagga
    68041 aatccagctc attcgtgagt atgaattgat tatgctcgac tatagtgagg acaagcaggc
    68101 gcgtttggaa cgtgtcatgg cagagatgga ctctctccaa gcttgggaaa tcgagagtca
    68161 ggtcaagacc gttcttagca aattgggcat tcaagactta tctactcctg ttggggaatt
    68221 gtcaggtggt ctgagaagac gggtacagtt ggcacaagtc ttacttggca accacgacct
    68281 tttgcttttg gatgagccga ccaaccatct ggatattgcg attattgagt ggctgaccct
    68341 ctttttgaaa aattctaaga agaccgtcct ttttatcact cacgatcgtt atttcttaga
    68401 cgctttgtca acacggattt tcgagttgga gcgagcaggc ttgacagaat atcagggcaa
    68461 ttaccaggac tatgttcgcc ttaaggcaga acaggacgag cgcgatgcag ctctacttca
    68521 taaaaaagaa caactctaca aacaagaact ggcctggatg cgcagacaac cgcaggcacg
    68581 tgcgactaag cagcaggctc gtatcaatcg tttccacgac ttgaagaaag aactttcagg
    68641 tggcgttgct gagacagact taactatgaa ctttgaaacc agtcggattg ggaagaaagt
    68701 catcgagttt caggatgttt cctttgccta tgaaaacaag cccattttgc aagattttaa
    68761 tctcttggtg caggccaaag accgtatcgg aatcgttggg gacaatggtg ttggaaaatc
    68821 aaccctactt aacctgattg caggaagtct tgagccgaca gcaggacaag ttgtgattgg
    68881 ggaaactgtt cgcatcgcct atttctctca gcaaattgag ggtttggatg aaagcaagag
    68941 agttatcaat tacttgcagg aagtggcaga agaggtcaag accagtggcg gttctacgac
    69001 ttcgattgca gagttgctgg agcagttcct tttcccacgt tcgacgcatg gaaccttgat
    69061 tgagaaattg tcagggggtg agaaaaaacg tctttatctc ctcaaactgc ttttggaaaa
    69121 accaaatgtt cttcttttag acgagccaac caatgaccta gatattgcaa ctttgacagt
    69181 cttagagaat ttcttgcaag gttttgcagg tcccgtttta acagtcagtc acgaccgcta
    69241 tttcttggat aaggtagcga ccaagattct cgcttttgag gatggcaaga ttcgtccttt
    69301 ctttggtcat tacaccgact atcttgatga aaaagctttt gaaacagata tggccaatca
    69361 agtgcaaaag gccgaaaagg aaaaagtggt caaggttcga gaagacaaga aacgcatgac
    69421 ctaccaagaa aagcaggagt gggcaagtat tgaaggtgat attgaaacct tggaaaaacg
    69481 tatcgctgct attgaagagg aaatgcaggc taacggctct gactttggta agctggctac
    69541 tctccaaaaa gaattggatg agaaaaatga agcactcctt gaaaaatacg aacgctatga
    69601 gtatctcagt gaatttgata gttaagacta ttcgaaaatc aaagtgcaaa ctatgtcggc
    69661 ttcacattgc cgactcaagt acagcctgtg accggcttcc taatttgcac tttgattttt
    69721 attgagtata aaagaataga aaaatcccgt ctcatgaaag gatttctcta ttcttttttg
    69781 gtttcttgat gaaagatatt ttgccaggtt tcgtggcgac gccagatact ggtatggatg
    69841 ataccatcta actcatagca gatgagtttg gttttttgac tgatggaagt aatttgaatg
    69901 tccttgatag cagaatttaa ctcttttttg gttttataag cctctttatc catctgctct
    69961 ccatcttggc gaatatagac aaaatcatca gtcaagagtt cttctagttg gtttccttgg
    70021 tcaatcaatt gttcacgcat aagcaatttt ttatagacat tgtctaaaat ttcatcctca
    70081 gggataggtg ctggttcgat atggacatcg gtatcaaaga cgccaaaacg ctcctccagc
    70141 atagactcga cctgatccgc gatttcatgg ctttcaaaaa cagacaagtc aggattcatc
    70201 tctagtgtaa tatccaggta gatgttgcta ccgtaggtac gacctctttg ggacttaacc
    70261 ttgctaattt tgggaatttc catgatggcc ttttggtagt cctcaagcag acggtcgtcg
    70321 aagccatctg aaaggctaaa ggaagactcg atgaagatat cataggcagt cttcaagata
    70381 aagaaagtga tgatgatagc aaccagtttg tccacaatgg gataattgaa actgctagct
    70441 aggatggcaa tggtcgtacc aagtgaggta acagcgtcag aaagattgtc cttagcggca
    70501 gccttcaggg ccttggagtt ggatttctta ctgagacgag tattgtagag atagaccatg
    70561 aacattatcg atgcagaaat gattcccaga gttgcaccaa gagggtcaat aaccgtttct
    70621 tcacgactga gaattttctg aatggtatcc cttagaacat caaagccaac atagaacatg
    70681 ataatagaag tgatcaagct agccaaatcc tcaatcttcc agtggccaaa acggtggtct
    70741 cggtcagcag gctgtcgtgc catccgaatg ccaatcaaga gggcaacatt tccaatgatg
    70801 tccgacacgt tgttaaaacc atcggccacc aaactggatg aatgaaggag atgaccagct
    70861 gctaatttgg ctgcagacaa gatcaaatag gtcgaaatac tgataatggc tccacgctca
    70921 gctaacttga gatttgagat agattgcttc attcaacttc ctttctagtc acatagcatt
    70981 ctaccattat actggttttc aaggaaaaat tcaaataagg cagtttttac tctttgaaaa
    71041 ctccccaaaa tttggtataa tggtactact caagggagta gctggcagaa acctgtgata
    71101 gtgtcgtcat tccgaatttt atgctgaaaa gtatgctttc cggccctatc ttaaacagcg
    71161 agacttgtta tgattaacag gtctcttttt gtttgtcgtg aaaagatatg acagaaagag
    71221 agtctgtttt gcacacaatg tcaaggagga gacacatgtc aaaagaacaa aaacgccaag
    71281 cgttttatac tcagagccct gaagaggtct tgcaggctat ggatgcgacc gagcaaggtt
    71341 tgtcatcaag tgaggcggaa aagcgccttg ccgaatttgg gcacaatgaa ctcgaagaag
    71401 gcgagaaacg atcaatcttg gtcaaattca tcgagcaatt taaggatttg atgattatca
    71461 tcctagttgc ggcagcaatc ttgtcagtcg tgacttctgg tggggaagat atcgcagatg
    71521 ccattatcat cctagctgtg gttatcatca acgctgcctt tggtgtttac caagaaggaa
    71581 aagctgaaga agctattgaa gccctcaaat ccatgtctag tccagttgcc cgcgttcttc
    71641 gtgatggaca catggcagag attgactcta aagaattggt accaggcgat atcgttgccc
    71701 ttgaagcagg tgacgtggta ccagcggacc tacgtttgat agaagccaac tctcttaaaa
    71761 ttgaagaagc agccttgaca ggtgaatctg taccagtcga aaaagacttg tcagtcgagc
    71821 ttgcgacaga tgctggtatt ggtgaccgtg tcaacatggc cttccaaaac tcaaacgtaa
    71881 cctatggtcg tgggatgggt gttgttgtca atacaggtat gtacactgaa gttggtcata
    71941 ttgctggtat gcttcaagat gcggatgaga ctgatacacc actcaaacaa aatttgaaca
    72001 acctttctaa ggtcttgacc tatgctatct tggtcattgc ccttgttact tttgtagtgg
    72061 gtgtcttcat tcaagggaaa aatccacttg gtgagttgtt gacttctgtt gcccttgccg
    72121 ttgcagccat tccagaagga cttcctgcta tcgttaccat cgttctttct cttggtactc
    72181 aagttttggc caaacgacat tccatcgttc gtaagttgcc agcagttgaa acacttggtt
    72241 caactgaaat catcgcttct gataagactg gtacgctgac tatgaacaag atgacagtcg
    72301 aaaaagtctt ctacgatgcg gttctacatg actcagctga tgatattgaa ctaggtcttg
    72361 aaatgccact acttcgttca gttatcttgg ccaatgatac gaaaatcgat gtggaaggta
    72421 acttgattgg tgacccaacc gaaacagcct ttatccaata tgccttggac aagggctatg
    72481 atgtcaaagg tttcttagag aaatatcctc gtgtagctga attgccattt gactctgacc
    72541 gtaagctcat gtcaacagtt cacccattgc cagatggtcg tttccttgta gcagtcaagg
    72601 gtgcgccaga ccaactctta aaacgttgtc ttcttcgtga taaggctggg gatattgctc
    72661 cgattgatga gaaggttaca aatctcattc atacaaacaa ttctgaaatg gctcatcaag
    72721 ccttgcgtgt ccttgcaggt gcttataaga ttatcgatag tattccagaa aatctcactt
    72781 ctgaagagct tgaaaatgat ttaattttta ctggtttgat tgggatgatt gatcctgaac
    72841 gtcctgaagc tgctgaggct gttcgtgtgg ctaaggaagc tggaattcgt ccaattatga
    72901 ttacaggtga ccaccaagac accgcagaag ctattgccaa acgtttggga atcattgacg
    72961 caaacgatac agaagaccac gttttaactg gtgctgagct caacgaatta tctgatgaag
    73021 actttgaaaa agttgttggt caatactctg tttatgcccg tgtgtctcca gagcacaagg
    73081 ttcgtatcgt caaggcttgg caaaaacaag gtaaggtcgt tgccatgaca ggtgacggtg
    73141 tcaatgatgc cccagctctg aaaacagcag acatcggtat cggtatggga atcactggta
    73201 cagaggtttc taagggggct tctgatatga ttcttgcaga tgataacttt gcgactatta
    73261 tcgtcgcagt ggaagaagga cgtaaggtct tctcaaatat tcaaaagact attcagtacc
    73321 tactttctgc caatactgct gaagtattaa ccatcttcct atcaaccttg tttggttggg
    73381 acgtcttgca gccagttcat cttttgtgga ttaacttggt aacggatacc ttcccagcaa
    73441 ttgcactagg tgttgaacct gcggaacctg gtgtcatgaa tcataaacca cgtggacgca
    73501 aggcaagctt cttctcaggt ggtgttttga gttctatcat ttatcaaggt gtactccaag
    73561 cagctcttgt tatgagtgtt tatggccttg cgattgctta cccagttcat gtgggtgaca
    73621 atcatgctat tcatgcagat gccctaacga tggcctttgc aacccttggt ttgattcagc
    73681 tcttccatgc ctacaatgtc aagtctgtct accaatccat cttgacagtt ggcccattca
    73741 agtctaagac ctttaactgg tccatcttgg tatcctttat ccttctcatg gcaacaatcg
    73801 ttgtagaacc gcttgaagga atcttccacg taaccaaact agacttgtca caatggggaa
    73861 ttgttatggc tggaagcttc tcaatgatta tcatcgtcga aatcgttaag tttattcaac
    73921 gcaaactcgg ttttgacaag aatgcgattt aagggaggtt tcggatgtca gcatatcaat
    73981 taccgaccgt atggcaggat gaagctagta atcaaggagc ttttacgggg ttaaacagac
    74041 caacagcagg tgcccgtttc gaacaaaact tgccaaaagg agaacaagct tttcagcttt
    74101 attcactggg aacaccaaat ggtgtgaagg ttactatctt attggaagaa ttactagaag
    74161 ctggttttaa ggaagcggct tacgacttgt ataagattgc tatcatggat ggggatcaat
    74221 tcggctcaga ctttgtgaag ctcaatccaa attccaagat tccagcctta ttggaccagt
    74281 caggtactga aaacgtaaga gtctttgagt ctgctcatat tcttctttac cttgctgaga
    74341 aatttggagc ctttttacca agtaatcctg tggaaaaggt agaagttttg aattggctat
    74401 tctggcaagc aggtgcagca ccttttctag gtgggggatt tggacatttc ttcaattatg
    74461 ctcctgaaaa attggaatat cctattaacc gttttacgat ggaagtgaaa cgccagttgg
    74521 atttattgga taaggaattg gctcagaaac cttatattgc aggcaatgac tatacgattg
    74581 cagatattgc tatctggtct tggtatggac agttagttca aggaaatctt taccaaggtt
    74641 ctgcaaaatt tttggatgcc tcaagttatc aaaatctagt aaaatgggca gaaaaaattg
    74701 ccaatcgtcc agctgttaag cgtggattgg aagtaactta tacagaaatt aaatagcaaa
    74761 aaagtcatct tcggatggct ttttgctaca gttgagggaa agggtttgca gttatcggct
    74821 tttgtgctat aattgctata atatagtaaa aagcaagagg agtgtgagga agtggaaaag
    74881 aaaattgtga aggatatctt atttttatct caagtgtctc agccggcaag tcaggaggac
    74941 ctttatcttg ccagagattt gcaggataca ctcttagcaa atcgtgatac ctgtgttggt
    75001 ctagctgcca atatgattgg ggtgcagaag cgcgtgatta tctttaatct tggcttggtt
    75061 cccgtggtca tgtttaaccc agtgcttctg tcctttgaag gatcttatga ggcagaagaa
    75121 ggctgtttgt ccttggtagg tgtgagatca actaagcgtt atgaaaccat aaggcttgcc
    75181 tatcgtgaca gcaagtggca ggaacagacc attaccttga caggcttccc agctcagatt
    75241 tgccagcatg agctggatca cttggaagga cgaatcattt aggaggaaag caaatgaaac
    75301 gaatagtctt tgaacttatt tttatcgcaa cgacctggta tatcttttta ccgcccctta
    75361 acctgaccag ctgggaattt ctcttcttcc tctgtgggca tttgttagtt gtggcaatct
    75421 tatttggctt tggcaagggg ataaaccttg tcaaaacggt tcatgtgcgc cacggtaagg
    75481 cggaagctgc cttaaatctt gagggtttca aaatcaatcg gttagggaaa attctgttag
    75541 cttcgattgg aggaattctt ctcttggcag ctttggtttc cttggtaact tccagcatgt
    75601 ttcaggctaa aaattatgcc aatgtagtca cggttacgga aaaagacttt actgaatttc
    75661 ctaggagtga caccagtaag gttcctatcc tagatagaag tactgctgaa aaaattggag
    75721 accgctactt gggttcccta accgataagg tgtcgcaata cgtagcggca gatacctata
    75781 cccaattgac aattgatggg aaaccttatc gggtcacacc actagaatat gcagacccta
    75841 tcaaatggtt taacaatcaa gccaagggaa tcggtgagta tatcaaggtg gacatggtaa
    75901 ctggaaatgc ggatttggtg gacttgaaga caccaatcaa gtattcagac tcggagtatt
    75961 ttaaccgtga tgtcaaacgt cacctgcgct tgaagtaccc gactaaaatc tttaaaactc
    76021 catcttttga ggtggacgat gagggcaatc ctttctatgt agcaacggtt taccaaaagc
    76081 aatttggact tgcggttcct cgtcctgctt cagtcattat cttggatgct acaaatggag
    76141 aaaccaagga atacagctta tcagatgttc cagaatgggt ggacagggtc tatccagcag
    76201 aggaaaccat tgagcaaatc aactacaacg gcaagtacaa ggacggtttc ttgaatgcca
    76261 tgatttccaa gaaaaatgtg acccagacta ccaagggcta taattacttg tctatcggta
    76321 atgacatcta tctctacaca ggtgtgacgt cggctaatgc ggatgagagt aatcttggtt
    76381 tcatccttga aaatatgcga acaggagaaa tcactaagta tagcttggct tctgcgacag
    76441 aagaatcagc ccgtgaatca gcagaaggtg ctgttcagga gaaatcctac aaagcaacct
    76501 tcccaatcct catcaacctc aatgacaagc ctctctacat catgggctta aaggacaatg
    76561 ctggcttggt caaagagtac gccctggtag acgcagtcga gtaccaaaat gttatcgttg
    76621 ctactacagt ggaagagatg ctcagcaagt atgccaataa aaacgacctt gaaattgaca
    76681 atgcaacgac agaaagcatc aagggagtag tagcagacct caaatcagct gttatcaagg
    76741 gagacactgt ctacttcttt aaagttgatg gcaagatata caaggtcaag gcttcagtat
    76801 ccgatgacct tccttacctt gaaaatggta aaaccttcga aggtcaagta ggaaaagaca
    76861 attatctcaa gacctttaaa gtacaataat actcttcgaa aatctctagc tctatctgca
    76921 acctcaaaac agtgttttga gcagcctgcg gctagtttcc tagtttgctc tttgattttc
    76981 attgagtata aaaaaggttt atttaataaa tatatgttat aataaggtaa attaagccta
    77041 atggaggaca aagaaatggg tttttatttg atggttgctt caatgctact cggactgctc
    77101 gctttgaaga taggtttttc tcagttcaag gagaaaaaag ataaattctt atctatctta
    77161 acaagtttag ctggcacagc ccttgttctc gtggctgtct ggttaggatg gcccaaataa
    77221 atagaaaaac ctcggtcaaa ccgaggtttt tcaaatgaat ttcttggttg tggctaaaaa
    77281 atatgctaca ctatcaatat gaaaatttta atcccaacag caaaagaaat gaacacagac
    77341 ttgccaagta tcgaggcaat tcctttaaaa ccagaaagtc agaccgtgct tgatgccttg
    77401 gctctctatt ctgccagtca attggagagt ttctacaagg tatcggctga gaaagcggcg
    77461 gaagaatttc aaaatatcca agctttgaaa aggcaaactg ctcaacacta tccagccttg
    77521 aaactttttg atgggcttat gtaccgcaac attaagagag ataagctgac cgaggcggaa
    77581 caagattatc ttgaaaatca tgtcttcatt acctcggctt tgtacggtgt tgttccagcc
    77641 ttgtcaccca tggctcctca ccgtttggat tttttgatga aattaaaagt cgctggtaag
    77701 actttgaaga gccattggaa ggcagtctat gatgaagctc tgaagaagga agaagtgatt
    77761 ttctctctct tgtcatcaga gtttgagact gtattttcta aggaaatcag agcaaagatg
    77821 gtgaccttca aattcatgga ggatagaggc ggtcagctga agattcactc aactatctcc
    77881 aagaaagcgc gcggggcctt tctaacagct ttaatagaaa atcaagtaca aactgtgggg
    77941 gaagcacgtc gcttgaactt tgctggattt gtttaccgag aagatttgtc acaaccacag
    78001 ggattggttt ttgtaaagga agtatagaaa tcagatattt tgtatttggc aatatgtatc
    78061 atcagctgtt ttagtttata aatgagaaaa aaagcgaaca agctagtctt ctgagtgtca
    78121 gaaaagtagt cttgttcgct tttattatgt tatactcttc gaaaatctct tcaagccacg
    78181 tcagcgtcgc cttaccgtat atatgtcact gacttcgtca gttctatcta caacctcaaa
    78241 gcagtgcttt gagcagcttg cggctagctt cctagtttgc tttttgattt ttattgagtg
    78301 ttagttactt gatagcttcg accaagtctt gagcttgttt ttcaagtgag tttaggactg
    78361 tttcttcaag aaccaatttt ccgtctgccc aggcagagtc attaacacgt gcagcagtga
    78421 aatcaccaac gccttgtgta cggataaatg gcaagaggtc tttgtagata gcgaaaagtt
    78481 gatcgtgccc tgcattggct acagatgata ctgtgacaaa cttgtcttga agggcagaaa
    78541 cgccacgtgt atcagacaag tcaagggcac gagatagcca gtcaagcaag tttttcactg
    78601 taccagggat agagaagttg tagactggag agaaaatcca gatagcatcc gcaacgagaa
    78661 ctgcttcacg agcagcagct acagctggat gtgttggaac ttccaaatct tggctgaaga
    78721 gaggaagggc tgaataatca aggtagctaa cttccgcttt accagcaaga gctttctcag
    78781 cttcgagcgc catttggtgg ttgaaagaac cttgacgtag tgatccgacg ataaataata
    78841 cttttttaga catgatgtgt ctcctttttc ttaaaatttc gagaactctc tcgttgttat
    78901 aaaatatatt acaacaaaac aaaagaactt gcaagaaatt tgctcagagt ttatttgaaa
    78961 attgtaaaat ttcggaaact ctagtcattt gtgactgaaa aagtaagaac tgtttcactt
    79021 tcaaaatcgg ttttgtttga agggagaaat agaattggtt gctcaaagca cagctttgag
    79081 gttgcagata aagctgacgt ggtttgaaga gattttcgaa gagtattctt atattcactt
    79141 gtaataaagc ttaatagatg gtaaaataga cgagtgaaaa aaagacaaaa caaagcaaaa
    79201 aataatctac tgtggcagta tggtctaggg atgacgattt tgtttgtggt tatcagtgct
    79261 tcctttctgt atatggtttc tcttagcatg aaaccctatc aaacagctaa aagtgaagga
    79321 gaaaaattag ctcagcagta tgcaggatta gagaaggctg atcaggttga tttatacaat
    79381 ggcttggaat cttattacag cgttcttggt cgtaataaac agcaagaagc gcttgctgtc
    79441 ctgattggta aagatgacca taagatttac gtttatcagc taaatcaggg tatttcacaa
    79501 gaaaaagcag aaacggtttc taaggaaaag ggagctggcg agattgacaa gataaccttt
    79561 ggtcgttatc aagacaagcc aatctgggaa gttaagtcag gatctgattt ttatctagta
    79621 gattttgaaa caggagcatt ggtcaataag gagggcctat gaaactatcc aaccgtgttt
    79681 tagaaatgga agaaagtgtg actttggctg ctggagcccg tgccaaagca ctgaaggctg
    79741 agggtagaga tattttgtct ctaaccttgg gtgagccaga tttcactact cccaaaaata
    79801 tccaagatgc cgccattgca tcgattcgag atgggcgtgc ttctttttat acagtaacct
    79861 caggtctgcc agagcttaag gcggtggtca atagctactt tgagcgcttt tacggctatt
    79921 ctgtagcgtc aaatcaagtg acagtcgctg cgggagccaa atattctctc tataccttct
    79981 ttatggctgt ggtcaatcca ggtgatgaag tcatcatccc aaccccatac tgggttagct
    80041 atggagatca ggtcaagatg gcagaaggcg ttcccgtctt tgtttctgct aaggaagaca
    80101 atcactttaa ggtgaccgta gagcagttag aagcagctcg cactgacaag accaaggttt
    80161 tggtgctgaa ttcgccatct aatcccacag gtatgattta cacccgtgag gaactcttgg
    80221 caattggaaa ctgggctgta gaaaatgata ttctcatcct agcagatgat atctatggcc
    80281 gcttggttta taatggtcat gagttcacac cgatttctag cctatcggaa gcgattcgca
    80341 agcaaacagt ggtcatcaat ggtgtgtcta aaacctatgc catgactggt tggcggattg
    80401 gttatgccgt tggagaagca gacattatcg ctgccatgtc caagattgca ggtcaaacaa
    80461 cttcgaatcc gtcagcagta gcccaatatg cagcagttga ggctctatca ggtgagcaag
    80521 atactgtaga aagcatgcgt caggcctttg aggaacgtct taataccatc tatcccctcc
    80581 ttgcagaggt gccaggattt gaagtggtca aaccacaagg ggccttctat ctcttcccaa
    80641 atgtcaaaaa ggccatggag atgaaaggct acacggatgt gacagacttt acaactgcta
    80701 tcttagaaga agccgaagtg gccttggtaa caggagctgg atttggagca ccagaaaatg
    80761 tccgcctcag ctatgcgaca gacctagaca cgcttaaaga agcagtcgaa cgcttgaaag
    80821 catttatggg tagtgagaat gattgatcat tttgagatta aggtaaagga tttacaaatt
    80881 tcagaaggat tttataggag ttttctcgct cctttggact ataaattggc ttttaagact
    80941 agttctctaa ttagttttct atccccgaac agccctcatc ctggtggtga tttttggctg
    81001 actcagggaa cacaagatcc tgttcatttt gcttttttag cagaaaataa ggaagaagtt
    81061 caggcttgtt atgaggctgg cttagaggca ggtgggcgag acaatggggt tcctggttat
    81121 cgaagtgagc atccgattta ttatgctgct tttatgattg acctggatgg gaacaatata
    81181 gaggtggttt gccataaaga ataaaaaaga aaaggaaaaa taatgacaaa acgtgtaacg
    81241 attattgatg taaaagacta tgttggtcag gaagtgacga ttggcgcttg ggttgccaac
    81301 aaatcaggaa aagggaaaat cgctttctta caattgcgtg atggaacagc cttctttcaa
    81361 ggtgtggctt ttaaaccaaa ctttgtcgaa aaatttggtg aagaagtggg acttgagaag
    81421 tttgatgtta tcaaacgctt gagccaagaa acgtctgttt atgtgacagg tattgtcaaa
    81481 gaggacgaac gttctaaatt tggctatgag ttggacatca cagacatcga agtgatcggt
    81541 gaatctcaag actacccaat cacaccaaaa gaacacggaa cagacttttt gatggataac
    81601 cgtcacttgt ggctacgctc tcgtaagcaa gtagctgtgt tgcaaatccg taacgctatt
    81661 atctatgcaa cttatgagtt ctttgacaag aatggtttta tgaagtttga cagcccaatt
    81721 ctttcaggaa atgcggcaga agattctaca gaactctttg aaactgacta cttcggaacg
    81781 ccagcctact tgagccaatc aggtcagctt tacctagaag caggggctat ggctcttggt
    81841 cgtgtctttg actttggtcc agttttccgt gctgaaaaat caaaaacacg ccgtcacttg
    81901 actgagttct ggatgatgga tgctgagtac tcatacttga cacatgatga gtcgcttgac
    81961 ttgcaagaag cttatgtgaa agctcttcta caaggtgttc ttgaccgcgc gcctcaagcc
    82021 ttggaaacct tggaacgtga tacagaactc ttgaaacgct acattgcaga gccattcaaa
    82081 cgtatcactt acgatcaagc cattgacctc ttgcaagagc atgaaaatga tgaagatgct
    82141 gactacgagc atcttgagca tggtgatgac tttgggtcac cacacgaaac ttggatttca
    82201 aaccactttg gtgtgccaac atttgtcatg aactatccag cagccatcaa ggccttctac
    82261 atgaaaccag ttcctggaaa tccagagcgc gtgctttgtg cagacttgct tgctccagaa
    82321 ggctatggag aaattatcgg tgggtctatg cgtgaggaag attacgatgc ccttgtcgct
    82381 aagatggatg aacttggcat ggatcgtaca gaatatgaat tctaccttga ccttcgtaaa
    82441 tacggtacag ttccacacgg aggatttggt atcggtatcg aacgtatggt aaccttcgca
    82501 gcaggaacaa aacatatccg tgaagctatt ccattcccac gtatgttgca ccgtatcaaa
    82561 ccataagaac aggaaaacgc ccatgtggcg ttttttcgaa ttctagtgtt tttacttgcg
    82621 taaaaaaatt ttttctagta taatagttta ttgtgagcga acctcactta ccccttgcaa
    82681 agtcttgggg tcattagacc aaaaggagga acatatcaat ggctaaatac gaaattcttt
    82741 atatcattcg tccaaacatt gaagaagaag ctaaaaacgc tttggtagca cgttttgact
    82801 ctattttgac tgacaacggt gcaactgttg ttgaatcaaa aacttgggaa aaacgtcgtc
    82861 ttgcatacga aatccaagat ttccgtgaag gactttacca catcgttaac gttgaagcaa
    82921 atgacgatgc agctcttaaa gagtttgacc gtctttcaaa aatcaatgct gacattcttc
    82981 gtcacatgat cgtcaaaatt gacgcgtaag aaggtaaact atgattaaca atgttgtact
    83041 tgtagggcgt atgacacgtg acgctgagtt gcgttatacc ccatcaaatg tagcagttgc
    83101 gacttttact cttgcagtaa accgtacatt taagagtcaa aatggtgaac gtgaggctga
    83161 ttttatcaat gtcgttatgt ggcgccaaca ggctgaaaat cttgctaact gggctaaaaa
    83221 aggctcactt atcggggtga caggtcgtat ccagactcgt agttacgata accagcaagg
    83281 acaacgtgtc tacgtgacag aggtcgtggc tgagaatttc caaatgttgg aaagccgtag
    83341 tgtgcgtgag ggtcacacag gtggagctta ctctgcacca actgcaaact attcagcacc
    83401 tacaaattca gtaccagact tttcacgtaa tgaaaatcca tttggagcaa caaacccatt
    83461 ggatatttca gatgatgatt taccattcta atggacaact aaacttataa aggagaaaaa
    83521 acatggctca acaacgtcgt ggcggattca aacgccgtaa aaaagttgat tacatcgcag
    83581 caaacaaaat tgaatatgtt gattacaaag atactgagct tcttagccgt ttcgtttcag
    83641 aacgtgggaa aatccttcct cgtcgtgtaa caggaacttc agctaaaaac caacgtaaag
    83701 taacaacagc tatcaaacgc gctcgcgtaa tggctttgat gcctttcgta aacgaagatt
    83761 aaagaaaaga cccggttggg tctctttttc atgagcttga aaacaagaaa gcgaattaag
    83821 accccaacgg gtcttttttc acaagctttg aaatgagaga gcgagttagg ctcagtggct
    83881 ccctttttac gagtttgaaa acaagagaac acattaaaag cacgatggag ctttttcata
    83941 aatatgtctc ttttctcatc caagaaatta aaataaaaat gataaacttt ttgaaaatag
    84001 gggatttgcc tactttatga tataatggaa agagttagat tgaaagaggt agtgagatgg
    84061 acgcgaaatt aagatacaag gcaaagaaga tcaagattgt cttttttgat attgatgata
    84121 cattgcggaa ttcaaagaca gggtttattc caactacaat tcccactgtt tttaaacagt
    84181 tgcgtgaaaa aggaatttta ataggaatcg cctctggacg tggcattttt ggtgttgttc
    84241 cagagattcg tgatctcaag cctgactttt ttgtaacttt gaatggagct tatatcgaag
    84301 ataaaaaagg tcaggtcatt tatcagcatc agattgaaaa gtcagatgtt gaggagtata
    84361 tctcttgggc taagcaagaa ggaattgagt atggcttggt tgggagtcat gatgccaagt
    84421 tgtcgactcg caccgatatg atgagtgaag ctatcaatcc aatttatccc gacttagatg
    84481 tagatcccga tttccatgaa aaagaagata tctatcagat gtggactttt gaagataagg
    84541 gagatgactt gcacttgcct gacagtctct cagacaaact tcgcatggtt cgttggcatc
    84601 aacattcgtc tgatattgtg ccgatttcag gctccaaagc aacgggggtg gaaaaggttg
    84661 tggaacacct tggcttgaaa ccagagaagg tcatggtttt tggagatggt ctcaatgact
    84721 tggaactctt tgattatgct ggaatcagcg ttgccatggg aatttctcat gataaaatca
    84781 aagaaaaagc agattatatt acaaaaacat tagaagaaga tggcattttt gatgccttag
    84841 aagtatttgg tatggtagaa aaagaattgc attttccaca agtagacatt gaaacagtag
    84901 aaggtcctct tgcgactatt aagaccaatc acggagactt acgtatcaag cttttccctg
    84961 aacatgctcc taaaacagtg gctaactttg tatctctttc aaaagatggc tactatgatg
    85021 gtgtcatttt ccaccgtatt atcaaggact ttatgatcca aggtggagac ccaactggaa
    85081 ctggtatggg tggcgagtca atctacggcg aatcttttga ggatgaattc tcagaagagc
    85141 tttacaatat ccgtggtgct ctttccatgg caaatgctgg tccaaatacc aacggcagcc
    85201 agttctttat cgtgcaaaac caacacctac cttattcgaa gaaagaaatt actcgtggtg
    85261 gttggccaga accgattgca gaaatctatg ccaatcaagg tgggacacct cacctagacc
    85321 gccgtcacac ggtttttggt cagttagctg atgaagcatc ttacgctgtc ttggatgcca
    85381 ttgctgctgt tgagacagga gctatggaca agccagttga agatgttgta attgaaacta
    85441 ttgaaatcga ggactaagat gaaaatcggt gataagctaa aggggcgtat tacagggatt
    85501 cagccctacg gtgcctttgt tgagttagag acgggtgata cggggctgat tcacatttca
    85561 gaaattcgga caggatttat tgaaaatatt catgaaacct tgaaagtcga tgaagaggtt
    85621 caagttcagg tagtggattt agatgaattt acggggaaag ccagtctttc tatccgcact
    85681 ttggaggaag aaaagtacca gtttcctaga cggagacgct tttcaagcga ccgctttaac
    85741 tacggttttg ctccctttcg acgaatgtta ccaatctgga ctggagaagc cctgcaccat
    85801 ttaaaaaaga agaagtagtt tagagtttta tattttttgt aatgttaata taaatttgct
    85861 ataataggac catggaagaa gaacaattat taaaatcagg agagcgcatt aaccagctct
    85921 tttcgacaga tatcaaaatc attcaaaata gagaggtttt tagctattcg gtggatagtg
    85981 ttctcttatc acgatttcca cgttttccta agaaggggtt gattgtggat ttctgtgctg
    86041 ggaatggagc agtggggctt tttgctagca ctcgtactca agcacagata ttgtctgttg
    86101 agattcagga gcgtttggcg gatatggctg aacgctctgt ccgtttgaat ggattagagg
    86161 agcaaatgca ggtcatctgc gatgatttga aaaatatgcc tgctcacatt caggggagta
    86221 aggtggatat gattttgtgt aatccaccct atttcaaggt ggatccttat tctaatctga
    86281 acgagagtga acattatctc ttggctcgac acgaaatcac gactaatttg gaagaaatct
    86341 gtcgtagtgc tcagagtatt ctcaagtcta atgggcgttt ggccatggtt catcgtcctg
    86401 atcgacttct ggatattttg gatacgttaa aacgacataa tctagcccct aagcgcctgc
    86461 agtttgttta tccaaaaaga gaaaaggaag ccaatatgct tttgattgag gcgatcaagg
    86521 atggctcaac aagtggcttt aaggtcttac ctcctttgat tgtccacaat gatgatggct
    86581 cttatacgcc cgaaatcgaa gagatttatt atggatcata aggcttatat gtacgttctg
    86641 gagtgtcgtg atggatccta ctatataggc tatacgactg atgtgagaag acgcctcgct
    86701 atccacaata gtgggagggg agccaaatat acacgagcac gcttgccagt caaacttatc
    86761 tatgctcaag gttttgccag taaggaagaa gccatgtcgg ctgaagctct tctcaagcgt
    86821 aagaagaggc cacagaagga agaattttta tctgaaaatc aagatagaaa tttactcagt
    86881 tattttgaag aatcgtgggg agtcctttga ctcctcttac ctttgtcaaa aagcgaaaaa
    86941 aatgctacaa taaagaaaat aaacaaaatg aggtattatc atgtccaaga ttctagtatt
    87001 tggtcaccaa aatccagact cagatgccat cgggtcatct gtagcttttg cctaccttgc
    87061 aaaagaagct tacggtttgg atacggaagc tgttgccctt ggaactccaa atgaagaaac
    87121 agcctttgtc ttgaactatt ttggtgtgga agcaccacgt gttatcactt ctgccaaagc
    87181 agagggggca gagcaagtta tcttgactga ccacaatgaa ttccaacaat ctgtatcaga
    87241 tatcgctgaa gtagaagttt acggtgttgt agaccaccac cgtgtggcta actttgaaac
    87301 tgcaagccca ctttacatgc gtttggagcc agttggatca gcgtcttcaa tcgtttaccg
    87361 tatgttcaaa gaacatggtg tagctgtgcc taaagagatt gcaggtttga tgctttcagg
    87421 tttgatttca gatacccttc ttttgaaatc accaacaaca cacccaacag ataaaatcat
    87481 tgctcctgaa ttggctgaat tggctggtgt gaacttggaa gaatatggtt tggcaatgtt
    87541 gaaagctggt accaacttgg ctagcaaatc tgctgaagaa ttgattgaca tcgatgctaa
    87601 aacttttgaa ctcaacggaa ataatgtccg tgttgcccaa gtgaacacag ttgacatcgc
    87661 tgaagttttg gaacgccaag cagaaattga agctgcaatg caagctgcca acgaatcaaa
    87721 cggctactct gactttgtct tgatgattac agatatcgtc aactcaaact cagaaatctt
    87781 ggctcttggt gccaatatgg acaaggtcga agcggctttc aacttcaaac ttgaaaacaa
    87841 tcatgccttc cttgctggtg ccgtttcacg taagaaacaa gtggtacctc aattgactga
    87901 aagctttaat gcgtaagatt ttgggtgtca gctcaaaatc ggaaagtcta gtttgcctta
    87961 tatcgaaagg agtttcggct ccttttttct aggagtgaag tatgttagaa aatggcgatt
    88021 tgatttttgt gagagatggg tcagacatgg gacaggccat ccagacttcc acaggtaact
    88081 atagccatgt tgccatttat ttggatggga tgatttatca tgctagtgga caggctggtg
    88141 ttgtctgtca agaaccggca gacttctttg agtccaatca tttatacgac ctctatgttt
    88201 acccagaaat ggatatccag tcggtgaagg aaagagcttg caaacatctt ggagcaccct
    88261 acaatgcttc tttctatcca gatgcagctg gtttctactg ctcccagtat atagcagaaa
    88321 tcctacctat ttttgaaact attcctatga aatttggaga tggggagcag gagattagtg
    88381 atttttggag ggagtattac atagaactag gtctgcctgt tcctctgaac caagctggta
    88441 ccaatcctag tcagttggca gcatcgcctc tgttacaatg taaagaaagg aatcttcatg
    88501 attcagattt ttaatccatc tcgtttgacg agacagccat ttttggagaa ttgatccgct
    88561 atctggacca gtatgaggat gtgattctac gggaaattaa ggctcaattt ccagatgttg
    88621 cagttgataa actcatggaa gagtatataa aggcaggctt gattctacgt gaaaataagc
    88681 gctattacct caattttcct acgcttgaat cacttgatag tcttgaactg gatcaagaga
    88741 tttttgtcag agaagctagt ccggtctatc aagccttgtt ggagcagagt tttgagacgg
    88801 aattgcgcaa tcaaatcaat gcagctattt tagttgaaaa gacggacttt gcgcgcatta
    88861 aaatgaccct gtccaattat ttttacaagg tcaaacagca gtatcctttg acagaaaaac
    88921 agcaggagct ctatgacatt ttaggagatg ttaatcctga gtatgccctc aagtatatga
    88981 cggctttttt gttgaaattt ctcaaaaaat accagcttat gcagaaatgc cgtgatatct
    89041 ttgtggacag tttggttgtc ttaggctata ttgtgcaaaa tgaagatgga aagtatgagt
    89101 tggctatcga ttttgataag gagagattaa ctttctactt agcgtgattt cttgtttctg
    89161 agcacattgt ttgactttcc ttagtattcg gtataaacta tatgtaaccg gtaacacata
    89221 tcggaataaa ctaaaggaga caatcatatg tcacttgaaa acaaattgga acaagcaaca
    89281 ggcgctgtca aagaaggttt tggtaaagtt actggagaca gcaagacaga acttgaagga
    89341 gctgttgaaa aaacagttgc taaggcaaaa gacgttgtag aagacgcaaa aggtgctgta
    89401 gaaggtgccg ttgaaggttt gaaaaacgtt tttactaaag aataggaaaa aatcaagggt
    89461 ttcattttcc cttgattttt tctattctta taaataattt tctgcgacgg ctgtatctcc
    89521 tgggtaggat tctttcttgc cctggatgat ttggtaacaa tcggctccct tacccgcaat
    89581 aataactgca tctaattcgt gatttgtgat agccattgcc gccttgatgg cttcttggcg
    89641 atccgcaatc ttttcaacag gatgattgat gtagttacta atttcatctg caatggccat
    89701 tgggtcttca tagttagggt catcagcagt cagaaagact tgaatctcag ggtgttgatt
    89761 gaggaggagg ccaaagtcct tacgacgact ttctcccttg tttcctgttg atcccagaac
    89821 cagagcaatc tttccggttt gatgagtttc aaccacattg atgagttttt tcagactatc
    89881 cccattgtgg gcatagtcga tgaagacctt ggctccattt ttctgagtga ggacttccat
    89941 acgaccagga acgcgggttg cagcgatgcc ttttttgatg tcctcaagac ttgctccgag
    90001 acggagacaa gcaagtccag cagcaactgc attttcttgg ttgaagttgc caatgagttg
    90061 gatatcataa tctccagcga gtttacccgt agctgaaaag ctaaaggctt tggaattctc
    90121 gatttggtta tcaaattggc taccatagaa atcatggtct tgatcttcaa cctgttctct
    90181 caagactgag aagtggtcca tgtcactgtt aatgatgact gctcggctat tttccatcaa
    90241 gagacgcttg tggtagaaat agtcttcaaa gctagggtgt tcaatcgggc cgatatggtc
    90301 tgggctgata tttaggaaaa ctcccacatc aaaggtcagt ccatagactc gatggactag
    90361 ataggcttga ctggagactt ccatgatgag gtgagtacgg tcattttgca cagcctgatt
    90421 catcatgtca aagaggtcaa tactctcagg ggttgtcaac gctgacttaa agaaagtctc
    90481 gccatcaaga gttgtgttca tggtcgacaa catagcaggt ctatgccctt gagataagat
    90541 gttataggcg aaataggttg ctgttgtctt acccttagta ccagtaaagg caaggagttt
    90601 gagtttctct tgtggattac catagaactc catggcaatc aaactcatgg ctttctttat
    90661 atcgttcaca atgatgacag ggatatcgac ttcgtagtcc ttttcagcta cataccaagc
    90721 taaaccttgt gttatagcag aaagaaggta ttctttttta aaggcagcgc cttttgcaaa
    90781 aaaaagagtg tcttctgtta cttttcggct gtcgtagctg atgctatcaa aaataacttt
    90841 gctgtagttg tagtggtaat gaccttggtc aataatttcg cgaaaaaggc catctttctt
    90901 taaaatatct aatacggttt caatcttaat catactttct attgtaaacc gaaagtcgta
    90961 aatttacaag taacaaggaa aagtttataa tggaagataa ggagtttttc ctagttatca
    91021 aaattgaatg aggaatctat gtcgcacgaa aacaatcacc agcaggccca gatgttacgg
    91081 gggactgctt ggctaacggc tagtaacttt atcagtcgcc tactcggggc tgtttacatt
    91141 atcccttggt acatctggat gggggcttat gcagctaagg caaatggtct ctttaccatg
    91201 ggttacaata tctatgcttg gttcttgttg gtttcaacag cggggattcc agttgcggtg
    91261 gccaagcaag ttgccaagta taataccatg cgagaagaag agcatagctt tgccctgatt
    91321 cggagcttct taggctttat gacaggacta ggcctggttt ttgctttagt cttgtatgtc
    91381 tttgctcctt ggctagcaga cttgtctggc gtgggcaaag acttgatccc aatcatgcaa
    91441 agcttggctt ggggagtctt gattttcccg tctatgagtg ttatccgagg atttttccaa
    91501 gggatgaata acctcaaacc ctatgccatg agccaaattg ctgagcaggt cattcgtgtt
    91561 atctggatgc tcctagcaac ctttatcatt atgaagctcg gttcaggaga ttatctagca
    91621 gccgttaccc aatcaacctt tgctgccttt gtcggtatgg tagccagttt tgcagtcttg
    91681 atttatttcc ttgcccaaga aggttcactc aaaagagtct ttgaaacagg agataagatt
    91741 aacagtaagc gtctcttggt tgataccatt aaggaagcca ttccttttat cctgacaggg
    91801 tctgccatcc agctcttcca gattttggat cagctgacct ttatcaatag tatgagctgg
    91861 tttaccaact acagcaatga ggacttggtt gtcatgtttt cttatttctc agccaatcct
    91921 aataaaatca cgatgatttt gatttctgta ggggtttcga ttgggagtgt tggtttgcca
    91981 cttttgacgg aaaactatgt caagggggac ttgaaagcgg cttctcgtct cgttcaggac
    92041 agtctcaccc tactctttat gttcttgcta ccagcaacgg ttggagtggt tatggtagga
    92101 gaacctcttt atacggtctt ctatggtaag ccagatagtt tggctctggg cttatttgtc
    92161 tttgcagttt tgcagtctat tattttaggc ttgtacatgg tcttgtctcc aatgcttcag
    92221 gccatgttcc gcaaccgcaa ggccgttctc tattttatct atggttctat tgccaagcta
    92281 gtcttgcaac tacctaccat cgccctcttc cacagttatg gtcctttgat ttcaacaacc
    92341 attgctctca tcattcctaa cgtcttgatg tatcgggata tttgtaaagt aactggtgtc
    92401 aagcgcaagg tgattttgaa gcgaaccatt ttaatcagtt tgctgaccct agtcatgttt
    92461 ctgttaatag gaaccatcca gtggctgtta ggatttttct tccaaccaag tggacgtttg
    92521 tggagcttct tttatgtagc tcttgtcggt gccatggggg gtggacttta tatggttatg
    92581 agtctgcgta cctatttatt agataaggta ataggaaaag cccaagcaga tcgcctgcga
    92641 gcaaaattta agctttcgta aggtagcatt tataaataaa aggaataagt tgaacaatct
    92701 tttaggagaa cttgaaactt attccttttt tagcgtcaaa atagctaaaa ttatctttca
    92761 aaaatagaaa atgaggtttt tttgattttt tggaaaaaac aattgactaa acaaaccaag
    92821 agttgtataa taaaacaaat atttaaagca ggaggttctg gaaatgaaaa agtctaagag
    92881 caaatatcta accttggcag gtcttgtcct gggtacagga gttttattga gcgcgtgtgg
    92941 aaattctagc actgcatcaa aaacctataa ctatgtttat tcaagtgatc catctagttt
    93001 gaactatcta gcagaaaacc gcgcagcaac atccgatatt gttgcaaatt tggtagacgg
    93061 gttattagaa aatgaccaat atgggaatat tattccatca ttagcagagg attggactgt
    93121 ttctcaggac ggtttgacct atacctacaa acttcgtaag gatgccaagt ggtttacttc
    93181 tgagggagaa gaatatgcgc ctgtaactgc ccaggatttt gtgacaggtt tgcaatatgc
    93241 agctgataaa aaatcagaag ctttgtatct agtgcaggac tctgttgctg gtttggatga
    93301 ctatatcact ggtaaaacaa gcgacttttc aactgtcggt gtcaaggcac ttgatgacca
    93361 aacggttcaa tatactttgg ttaaaccaga actttactgg aattcaaaaa cacttgcaac
    93421 gatacttttt cctgttaatg cagatttcct gaaatcaaaa ggggatgatt ttgggaaggc
    93481 ggatccatct agtattttgt acaatggacc tttcttgatg aaagcacttg tctcaaaatc
    93541 tgctattgaa tataagaaaa accctaatta ctgggatgct aagaatgtct ttgtagacga
    93601 tgtgaaattg acctactatg atggtagcga ccaagaatca ctggaacgta attttacagc
    93661 tggtgcttat actacggctc gtctttttcc taacagctcc agctatgaag ggattaaaga
    93721 aaaatacaaa aacaatatca tctatagtat gcaaaattca acttcatatt tctttaattt
    93781 taacctagat aggaagtctt acaattatac ttctaaaaca agtgacattg aaaagaaatc
    93841 gacccaggaa gcagttctca ataaaaactt ccgtcaggct atcaattttg cttttgacag
    93901 aacatcttat ggggctcagt ctgaagggaa agaaggtgca acaaagattt tgcgtaacct
    93961 agtggttcct ccaaactttg tcagtatcaa gggaaaagac tttggtgaag ttgtagcctc
    94021 taagatggtc aactatggta aggaatggca aggtatcaac tttgcggatg gtcaagaccc
    94081 ttactacaat cctgagaaag ccaaggctaa gtttgcggaa gctaagaaag aactcgaagc
    94141 aaagggtgtt caattcccaa tccacttgga taagactgtg gaagtaacag ataaagtagg
    94201 catacaagga gttagttcta tcaaacaatt aattgaatct gttttaggtt ctgataatgt
    94261 agtgattgac attcagcaat taacatcaga tgagtttgac agttcaggct actttgctca
    94321 aacagctgct cagaaagact atgatttata tcatggcggt tggggacctg attatcaaga
    94381 cccgtcaacc tatctcgata tttttaatac taatagtgga ggagttctac aaaatcttgg
    94441 actagagcct ggagaagcca atgacaaggc taaggcagtt ggactggatg tctatactca
    94501 aatgttggaa gaagctaata aagagcaaga tccagccaaa cgttatgaga aatatgctga
    94561 tattcaagct tggttgattg atagttcttt agttcttcca agtgtttcgc gtgggggaac
    94621 accatcattg agaagaaccg taccatttgc tgctgcctat ggtttaaccg gtacaaaagg
    94681 ggttgaatca tataaatacc tcaaagtaca agataagatt gtcacaacag acgaatatgc
    94741 aaaagccaga gaaaaatggt tgaaagaaaa agaagaatcc aataaaaaag cccaagaaga
    94801 attggcaaaa catgtcaaat aaaatctaat tgtagataag tttgtgtaag aagtctttgt
    94861 gcttaaaaac gcataatatc aggtatataa aatcctagat gttatgcgtt ttgttatagg
    94921 aagatttatt agattttatc ctcaaattga gttattcccg actttatccg ttgaaatatt
    94981 ataaggagta tttatgaaat taaaattatt aagagtagat actaaggtga ttatggggag
    95041 tttcttactt gttctgtcta gtctacttgc tttgttgctt ccccttatct taaagggttt
    95101 aatagatggg agttctattg aaaatatagg ttccaaagta tttcaatcgt attggtcaag
    95161 ccttgttttc ttctattggt tactatctgt ttagtcaatc gggtgaaaaa agatagcaaa
    95221 aatcaggaaa aaagtgatag aggggttgat ttatgcagag aaatccttct ttgataagag
    95281 ccaaagtggg gagttgactt ctgccattgt caatgacatg agtgtcattc gtgagttttt
    95341 aattacgact ttcccaaata ttattctgag tttagttatg gtacttggtt ccattgtagt
    95401 cttatttagt cttgattgga atctttctct acttttattc atcactcttc cttgtatgat
    95461 gtttattatc ttgccccttt ccaatatcag tgaaaagtat agtcgtcgtt tacaggagga
    95521 aatttaacag ggcaattgac tgaaaagatt caagaacatg aattaattaa gactaaccaa
    95581 gcagagaaaa gtgtacagga tgttttggat aattgtattg aaagggtaca aaacaattca
    95641 ctgaaatcag atagggttac ttcttttgag accccgtttg ctctcttatt tatctttgcg
    95701 actatagctg tgatgctaac ctatgggggt tatcgggtca gcgcaggata tatatctgtg
    95761 ggaaccttgg tttcgttttt gatttacctc tttcaattac ttaatcctat tagtaatata
    95821 gctaattttg taactgttta ttctaggagc aagggatctt cagttgcact ggataacttg
    95881 cttgcagttc ctaaagaaaa atttgaggga ggaaaatcgg tatcaggaca agggttgaat
    95941 tttaaccatg tctattttgg ttatgatgaa aatcgacctg tcttaaagga tattacttgt
    96001 tcaattttca aggggcaaaa attgcttttg ttggaccatc tggatcagga aaatcaacga
    96061 ttgtgcgttt gttagagcgg ttttataaac cgctttcagg agatattcta atggagcaat
    96121 caagtatata tgattttaac ttaaaagaat ggagaagtaa aatcgcttgg gtttcacaaa
    96181 ataatgcagt cttatctggc agtattcgtg acaatctttg tctcggtttg aatcgcttag
    96241 taactgatga tgaattgatg aaagtgctag acttagtatc actaggtgat gagattcgct
    96301 ccatgaaaga gggactagat actgaagttg gtgaacgcgg acgattcttg tcaggggggc
    96361 aaagccaaag acttcaaata gctagaacct acttaaaaga tgctgaaatt cttatatttg
    96421 atgaagctac tgctaatctt gatgcggatt ctgagtatgc gattatcagt agcctctatt
    96481 ctgtattaaa ggagaagacg gttgtgatta tagcgcatag tttgtcaacg gtaaaagatg
    96541 tggattgtat tttcttctta gaggagggga aaatcactgg ctcaggaact cataaggaac
    96601 tactggaaaa tcatgagcgt tatgctcgtt ttgtgcagga gcaaatgata gagtgaagtg
    96661 tcttttgaga ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat
    96721 atagtttgaa actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg
    96781 tacaatagtt actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa
    96841 ttttggccca ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc
    96901 atttttcaac gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc
    96961 gcactaaaaa tccaactcgt agtaaggctg aggaagtctt ggcgactatt gagtcagcag
    97021 actatgcctt agcgactagc tcagggatgt cagctattgt actggccttt agcggctttc
    97081 cagtaggaag taaggtcttg gcagtgcgtg atctttacgg cggttctttt cgctggttta
    97141 accaagtgga gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga
    97201 ttgccgagtt agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga
    97261 tgttggaatt tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg
    97321 tggtggacaa taccttctat agccctatct accaacgtcc gattgaagat ggagcagata
    97381 tcgttctcca ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg
    97441 ttgtgaccaa tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg
    97501 cagtcttgtc tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttgtctcttc
    97561 gtatggagcg ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag
    97621 cagttaagga agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg
    97681 aaacacgcat tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg
    97741 gcggagtgga aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag
    97801 aagtacgcca ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg
    97861 atgctagaga tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga
    97921 aaatatgatt ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa
    97981 acagaaacgg atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg
    98041 cctgaaatcc gccaagccgt gcaaatttac gcagaccaac tggtttatgg ttatacctat
    98101 gccagtgaag acttaattaa ggaagttcaa aagtgggaag ctacacaata cggttacaac
    98161 tttgacaaag aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt
    98221 caaaccttta caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt
    98281 gctcgcagtg tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat
    98341 ggtctgtttg agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa
    98401 ctctatattc tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg
    98461 gagaagattg gccaactctg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac
    98521 caagatttga ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc
    98581 aaaaattttg ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa
    98641 aattcctatg cagtcattga aaatcctaag ttgagactag ctttccagaa acgcctgttg
    98701 gccaataatc agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga
    98761 tacggtaaag attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg
    98821 gtggatctat ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg
    98881 atttggcttg acttttcagc ttatgacctg actgatgaaa cattgcaaga gttgttgaga
    98941 aatgaagcta aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat
    99001 gcccgcatca atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg
    99061 gctacttttg ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct
    99121 attttcatag gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta
    99181 aattgattcc ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg
    99241 atatcatcaa ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct
    99301 atagtttaga ggatgatttg gttttttgtg cctgtgattt ttttcaaaag aggggttact
    99361 gtgtgcattt ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct
    99421 tgtggagtct ggaagaaggt catgaagaaa aagaggctgt tgaaaccaag gtaaccttgg
    99481 gtggcaagtt tttggatcga attttatctc caaaatcaga atgcgcctat gagttatcag
    99541 ctgtgggtca ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa
    99601 tcaatagcca aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc
    99661 agagaaagtc gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg
    99721 atgatgccag ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttt
    99781 cagacctctt tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc
    99841 agggtgtgaa tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct
    99901 accaaaccct gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa
    99961 cagaatactc ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt
   100021 atcagggagc agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc
   100081 gtcttctcaa ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat
   100141 ttgatagcag tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca
   100201 ccgtttcagc tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca
   100261 gggaagaaga taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat
   100321 ctagccgaca agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa
   100381 ttttccaagt ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct
   100441 taaaagcgga gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg
   100501 ggcatgttga cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc
   100561 agattgcctc caagggaggt ctcttggaaa tccagtttga ttttcaagat attgcccagg
   100621 aggaaatcga ccaagccatg caggtcttgg ttgccaatca ggatttttat attgattcgt
   100681 ctaatcaagt ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac
   100741 tggggcaatt tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt
   100801 tagctcatct ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg
   100861 cccaggattt gacacatcca gaggactttc ctcgacaggc aactcaggtt caggctgact
   100921 tgcgagatta tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg
   100981 gtgggatttt ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga
   101041 ctagtcaagt gacaaaagaa agtcgggttt tgattctcgc tccgtcaggt ttgatttaca
   101101 actgggcaga tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt
   101161 tgaaagcaag tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg
   101221 ccaccttccg tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag
   101281 atgaggctca ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg
   101341 tggtgccgtc ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt
   101401 ggtctatttt ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat
   101461 tgccagcaga gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag
   101521 aagttctgac tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc
   101581 agcaaaaggc tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt
   101641 cagaacagga atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc
   101701 aaatatgtga cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag
   101761 atagtctccg agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct
   101821 ctcagttcaa gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgacat
   101881 cctttaaaat tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta
   101941 accaaggaga aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc
   102001 tgacaggtgc agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc
   102061 aagccattgg ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg
   102121 tgaccaaggg aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg
   102181 tgtcacaagt attggatggc acagagtcac gtggtagtct gaccctagca gaaattagag
   102241 aaattttggg aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag
   102301 tgttgaaagg aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt
   102361 catgttgact gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat
   102421 caagggtgag tatcgagata aaaattattt agaatgggct cctattactg aagaaaaacc
   102481 agtaaaaccg attgaaaagc aagtcgaaaa acctaaaaag gctcctttag gggttaaaaa
   102541 agaaggaaag agctatgcgg aggtggcgcg tgaagaagcg cgtgcggact tgaaaaagaa
   102601 acgctctgct aactacctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag
   102661 tctagttaga cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt
   102721 tgtcaaatat agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc
   102781 tatccctacc aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt
   102841 tctaaagaag agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt
   102901 tgcccaagag ttgaatctga ccagaatgac agaatagggg agaaaacatg tcaaagacat
   102961 atcattttat cggaattaag ggatcaggga tgagtgcctt ggccttgatg ttgcaccaga
   103021 tggggcacaa ggttcaggga tcagatgttg aaaagtacta ctttacccaa cgcggtcttg
   103081 agcaggcagg aattaccatt cttccttttg atgaaaagaa tctagacggt gatatggaaa
   103141 ttatcgctgg aaatgccttt cgtccagata acaacgtcga aattgcctat gcggaccaaa
   103201 atggtatcag ctacaaacgt taccatgagt ttctaggtag ctttatgcgt gactttgtta
   103261 gcatgggagt agcaggagca catggaaaaa cttcaacgac aggtatgttg tctcatgtct
   103321 tgtctcacat tacagatacc agcttcttga ttggagatgg gacaggtcgt ggttcggcta
   103381 atgccaaata ttttgtcttt gaatctgacg aatatgagcg tcacttcatg ccttaccacc
   103441 cagaatactc tattatcacc aacattgact ttgaccatcc agattatttc acaagtctcg
   103501 aggatgtttt caatgccttt aacgactatg ccaaacaaat taccaagggt ctttttgtct
   103561 atggtgaaga tgctgaattg cgtaagatta cgtctgatgc accaatttat tattatggtt
   103621 ttgaagctga aggcaatgac tttgtagcta gtgatcttct tcgttcaaca actggttcaa
   103681 ccttcaccgt tcatttccgt ggacaaaact tggggcaatt ccacattcca acctttggtc
   103741 gtcacaatat catgaatgcg acagccgtta ttggtcttct ttacacagca ggatttgatt
   103801 tgaacttggt gcgtgagcac ttgaaaacat ttgccggtgt taaacgtcgt ttcactgaga
   103861 aaattgtcaa tgatacagtg attattgatg actttgccca tcatccaaca gaaattattg
   103921 cgaccttgga tgcggctcgt cagaaatacc caagcaagga aattgtagca gtctttcaac
   103981 cgcatacctt tacaagaacc attgccctgt tggacgactt tgcccatgct ttaaaccaag
   104041 cagatgctgt ttatctagcg caaatttatg gctcggctcg tgaagtagat catggtgacg
   104101 ttaaggtaga agacctagca aataaaatca acaaaaaaca ccaagtgatt actgttgaaa
   104161 atgtttctcc actcctagac catgacaatg ctgtttacgt ctttatggga gcaggagaca
   104221 tccaaaccta tgaatactca tttgagcgtc tcttatctaa cttgacaagc aatgttcaat
   104281 aggatgttcc catggaaatt ccaattaaga tcattcaggc aagcaagtct gatttgcctg
   104341 agataggggc acttcagacc tcgtcttttc cagctgaaaa gcagcaactt tcccatattt
   104401 tagaagaaag tatccgtaag tgtgcggata cctttcttct agctagggat gaaaatcaac
   104461 ttttaggcta tattttatca agtccccagt cagacaatcc gcaatgtcta aaagtacatt
   104521 ctttagtcat cgagtctgac catcagagac agggcctggg aacacttctt cttgcagcct
   104581 tgaaagaggt ggcagttgag ctggattgca aagggattcg tttggagagt cctgatgagc
   104641 tgctttccta ttttgaaatg aacggttttg ttgatgaaga agaaactttg ctctatgcaa
   104701 ctagccaggg ctatagtatg atttggttta atccctttta tctggaggaa caatgaaaat
   104761 cagacaagca agattagaag atttggatcg gattgttgaa cttgaatttg aaaatttttc
   104821 ggtcgaagaa gccattcctc cttctgtctt tgaagcacat ttgagagaaa ttcagacctc
   104881 ttttctggtt gctgaaaaag aaggaagaat catgggttat atcgaaggac cagttggcct
   104941 gcaccgccat ctgcaagacc agtcttttac agaagaaata aaagactata gtcatgagcc
   105001 tggtggttat atctctgtga cctgtctgtc tattgccaag gaggcacagg gactcggact
   105061 gggtcagaaa ttgctgacag ccttgaaaga agttgctctt gaagatgaga gagatggcat
   105121 taatctaacc tgtcatgact atctcatcgc ctactatgaa aaacatggat ttgtcaacga
   105181 aggccagtcc cagtcaacct ttgcagggga aacatggtat gatatggtct gggaaatgaa
   105241 aaaataagtt aggaaaagta tcatagattg ctttttttgg acttttaaga tataatatta
   105301 tggattatca acaaggagga aaaacttttg agtgaaaagt caagagaaga agagaaatta
   105361 agctttaaag agcagattct gagagattta gaaaaagtaa aaggctatga tgaagttctg
   105421 aaagaagatg aggcagtagt tcgcactcct gcaaatgaac cttcagctga agaactcatg
   105481 gctgattcct tgtcaacggt agaggagatt atgagaaaag ctcctaccgt gcctactcac
   105541 ccaagtcaag gtgtaccagc ttctccagca gatgagattc aaagagaaac tcctggtgtt
   105601 ccaagtcatc caagtcaaga tgtaccttct tctccagcgg aagaaagtgg atcaagacca
   105661 ggtccaggtc ctgttagacc taagaaactt gaaagagaat acaatgaaac cccaacaagg
   105721 gtagctgttt cctatacgac ggcagagaaa aaagcagaac aagcaggtcc agaaacacct
   105781 acgcctgcta cagaaacagt ggatatcatc agcgatacat cacgtcgtag ccgtagagaa
   105841 ggagcaaaac ccgttaaacc taagaaagag aagaagtcac atgtgaaagc ttttgtgatt
   105901 tcattccttg tattccttgc cttgctctca gcaggtggtt actttggtta ccagtacgtg
   105961 ctagattctt tgttacctat cgatgctaat tctaagaaat atgtgacggt tggaattcca
   106021 gaaggttcaa acgttcaaga aatcggtacg acgcttgaaa aagctggttt ggtaaagcat
   106081 ggtctgattt ttagttttta tgccaagtat aaaaattata ccgacttgaa agcaggttac
   106141 tacaatttgc aaaagagtat gagtacagaa gacttactca aagagttgca aaaaggtgga
   106201 acagatgaac cgcaagaacc tgtacttgcg actttgacaa ttccagaagg ttataccttg
   106261 gatcagattg ctcaaactgt gggtcaattg caaggtgact tcaaagagtc tttgacagcg
   106321 gaggctttct tggctaaagt tcaagatgag acgtttatca gtcaagcagt agcgaaatat
   106381 cctactttac tggaaagttt gcctgtaaaa gacagcggtg cgcgttatcg tttggaagga
   106441 taccttttcc cagctacata ctctatcaag gaaagcacaa ctattgagag cttgattgat
   106501 gagatgttag ctgctatgga taagaaccta tctccttact atagtactat caaatctaaa
   106561 aacttgacta tcaatgagtt gttgaccatt gcttccttgg tcgaaaaaga aggtgccaag
   106621 acagaagatc gtaagctcat tgcaggtgta ttctacaatc gtttaaatcg tgatatgcca
   106681 cttcaaagta atattgcaat cttgtatgcc caaggaaaac tggggcaaaa tatcagtcta
   106741 gctgaggatg ttgcgattga taccgacatt gattcacctt ataatgttta taaaaatgta
   106801 ggtctcatgc ctggtccagt cgatagtcca agtctggatg cgattgagtc aagcatcaat
   106861 caaactaaga gcgataacct ctactttgta gcagatgtca cagaaggcaa ggtctactat
   106921 gctaacaatc aagaagacca cgaccgcaat gtcgctgaac atgtcaacag caaattaaac
   106981 taaacaaact aaaattatgt gatacttcac ataattttct ttagaaaata ttatcagaag
   107041 aaagttgaga aaaatggcag aaaaaacata tcctatgacc cttgaggaaa aggagaaact
   107101 tgaaaaagaa ttagaagaat tgaaattggt tcgtcgacca gaagtggtag aacgcattaa
   107161 gattgcccgt tcatacggtg atctttcaga aaacagtgag tacgaagcag ctaaggatga
   107221 acaagccttt gtcgaaggac aaatctctag cttagaaaca aaaatccgct atgctgaaat
   107281 cgtcaatagc gacgcagttg cccaggacga agtagcgatt ggtaaaacag tcaccatcca
   107341 agaaattggt gaggacgaag aagaagttta tattatcgta ggttcagctg gtgcggatgc
   107401 ctttgcaggt aaggtttcaa atgaaagccc aattgggcag gccttgattg gcaagaaaac
   107461 aggtgacaca gcaaccattg aaacgcctgt tggtagctat gatgtaaaaa tcttgaaggt
   107521 tgaaaaaaca gcctaaaaac agaaaaagga gtggggaggc gatgtgcttc actcactcct
   107581 ttttccattt tgctattctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta
   107641 tatatggtta ctgactttgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
   107701 ttcgtcagtt tcatctacaa cctcaaaacg gtgttttgag cagcctgcgc ctagtttcct
   107761 agtttgctct ttgattttta ttgagtatta gatgtatagt gcattgaagt taaaatagta
   107821 cactttgatt tctaagacat tgttagaaat tagattaaat tccttaatcg atttgcgcat
   107881 gttttatttc atttcattat actttagatt ggaaaataag gaatcacata aatcgcaaga
   107941 aatagggaat ctgattcgtg tttataaccg ttcaaaaaga gaagaggctg aaagtgagcc
   108001 acttaatctt tatgtcgaag atgaaaaggg caatctcctt gcgggtttga tagcagagac
   108061 ttttggaaat tggctagaaa tcgagtattt gtttgtaaaa gaggaactgc gagggcaagg
   108121 aatcggttca aaactattgc aacaggcaga aagtgaagct aagaatcgaa attgttgttt
   108181 tgcctttgtc aatacttacc agttccaggc accggacttt tatcagaaac atggctacaa
   108241 ggaagttttt tctttgcaag actatctcta cattaggcaa agatattatt atcaaaagaa
   108301 tctgtaaggt gagtatggag gtggactgat atatatgagt aactatcgat aaataccagt
   108361 tataacctag aaattgtgtc tttctagacg atattgagga caatataatc gtagccccaa
   108421 aattaggaat caaggcttat caggttaaga aaagaagtga tgttgttgat attttaaaac
   108481 aatttattta aactaaaaac tctctatctt tttaaattga cattaatccg agattcccct
   108541 ctcggatttt gtgttgcttt cattaaattt acaggtaaga cttgctagct tcagtaaata
   108601 tacacaagtt tttcagaata gagtgaaatc caaaagaaaa tggaaataat gaaagctctt
   108661 gtaggcataa gaaaacacct ttgtgttata cttgttgttc aaccacaaac acaagaaagg
   108721 cacagagatg caaaaccatt atactacaaa aggcgaacaa agggaaatca aatagagaaa
   108781 ttgcctctct acttggaaaa gctcctcaaa ctatccacac tgaaatcaag cgt
//
LOCUS       DAVMCG010000003        94569 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVMCG010000003 DAVMCG010000000
VERSION     DAVMCG010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 94569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.003"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(144..2033)
                     /locus_tag="VYP66_000223"
     CDS             complement(144..2033)
                     /locus_tag="VYP66_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1849843.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            2171..3736
                     /locus_tag="VYP66_000224"
     CDS             2171..3736
                     /locus_tag="VYP66_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1849844.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            3736..4500
                     /locus_tag="VYP66_000225"
     CDS             3736..4500
                     /locus_tag="VYP66_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1849845.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(4699..4914)
                     /locus_tag="VYP66_000226"
     CDS             complement(4699..4914)
                     /locus_tag="VYP66_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849846.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(5785..7035)
                     /gene="ilvA"
                     /locus_tag="VYP66_000227"
     CDS             complement(5785..7035)
                     /gene="ilvA"
                     /locus_tag="VYP66_000227"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1849847.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(7085..7441)
                     /locus_tag="VYP66_000228"
     CDS             complement(7085..7441)
                     /locus_tag="VYP66_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1849848.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(7679..7915)
                     /locus_tag="VYP66_000229"
     CDS             complement(7679..7915)
                     /locus_tag="VYP66_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849849.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(8022..9044)
                     /gene="ilvC"
                     /locus_tag="VYP66_000230"
     CDS             complement(8022..9044)
                     /gene="ilvC"
                     /locus_tag="VYP66_000230"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1849850.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(9110..9586)
                     /gene="ilvN"
                     /locus_tag="VYP66_000231"
     CDS             complement(9110..9586)
                     /gene="ilvN"
                     /locus_tag="VYP66_000231"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1849851.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(9579..11279)
                     /locus_tag="VYP66_000232"
     CDS             complement(9579..11279)
                     /locus_tag="VYP66_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1849852.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(11480..13147)
                     /locus_tag="VYP66_000233"
     CDS             complement(11480..13147)
                     /locus_tag="VYP66_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1849853.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(13150..13515)
                     /locus_tag="VYP66_000234"
     CDS             complement(13150..13515)
                     /locus_tag="VYP66_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1849854.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(13672..13860)
                     /locus_tag="VYP66_000235"
     CDS             complement(13672..13860)
                     /locus_tag="VYP66_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1849855.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(13976..14152)
                     /locus_tag="VYP66_000236"
     CDS             complement(13976..14152)
                     /locus_tag="VYP66_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1849856.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(14263..14460)
                     /locus_tag="VYP66_000237"
     CDS             complement(14263..14460)
                     /locus_tag="VYP66_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1849857.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(14888..16432)
                     /locus_tag="VYP66_000238"
     CDS             complement(14888..16432)
                     /locus_tag="VYP66_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1849858.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            16645..16947
                     /gene="gatC"
                     /locus_tag="VYP66_000239"
     CDS             16645..16947
                     /gene="gatC"
                     /locus_tag="VYP66_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1849859.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDNGGDA"
     gene            16947..18413
                     /gene="gatA"
                     /locus_tag="VYP66_000240"
     CDS             16947..18413
                     /gene="gatA"
                     /locus_tag="VYP66_000240"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1849860.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAHVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TIQSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQVAAAFEATTDYHKQQPVIFGGDN"
     gene            18413..19855
                     /gene="gatB"
                     /locus_tag="VYP66_000241"
     CDS             18413..19855
                     /gene="gatB"
                     /locus_tag="VYP66_000241"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1849861.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LDGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            19984..20544
                     /gene="efp"
                     /locus_tag="VYP66_000242"
     CDS             19984..20544
                     /gene="efp"
                     /locus_tag="VYP66_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1849862.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            20566..20955
                     /locus_tag="VYP66_000243"
     CDS             20566..20955
                     /locus_tag="VYP66_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1849863.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            20948..21370
                     /gene="nusB"
                     /locus_tag="VYP66_000244"
     CDS             20948..21370
                     /gene="nusB"
                     /locus_tag="VYP66_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1849864.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(21420..21656)
                     /locus_tag="VYP66_000245"
     CDS             complement(21420..21656)
                     /locus_tag="VYP66_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1849865.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(21669..22142)
                     /locus_tag="VYP66_000246"
     CDS             complement(21669..22142)
                     /locus_tag="VYP66_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849866.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(22160..22345)
                     /gene="briC"
                     /locus_tag="VYP66_000247"
     CDS             complement(22160..22345)
                     /gene="briC"
                     /locus_tag="VYP66_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1849867.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(22507..23274)
                     /locus_tag="VYP66_000248"
     CDS             complement(22507..23274)
                     /locus_tag="VYP66_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1849868.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(23271..24137)
                     /locus_tag="VYP66_000249"
     CDS             complement(23271..24137)
                     /locus_tag="VYP66_000249"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1849869.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(24174..25541)
                     /gene="accC"
                     /locus_tag="VYP66_000250"
     CDS             complement(24174..25541)
                     /gene="accC"
                     /locus_tag="VYP66_000250"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1849870.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(25553..25975)
                     /gene="fabZ"
                     /locus_tag="VYP66_000251"
     CDS             complement(25553..25975)
                     /gene="fabZ"
                     /locus_tag="VYP66_000251"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1849871.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(25972..26457)
                     /locus_tag="VYP66_000252"
     CDS             complement(25972..26457)
                     /locus_tag="VYP66_000252"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1849872.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(26460..27695)
                     /gene="fabF"
                     /locus_tag="VYP66_000253"
     CDS             complement(26460..27695)
                     /gene="fabF"
                     /locus_tag="VYP66_000253"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1849873.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(27717..28448)
                     /gene="fabG"
                     /locus_tag="VYP66_000254"
     CDS             complement(27717..28448)
                     /gene="fabG"
                     /locus_tag="VYP66_000254"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1849874.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(28482..29402)
                     /gene="fabD"
                     /locus_tag="VYP66_000255"
     CDS             complement(28482..29402)
                     /gene="fabD"
                     /locus_tag="VYP66_000255"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1849875.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(29395..30369)
                     /gene="fabK"
                     /locus_tag="VYP66_000256"
     CDS             complement(29395..30369)
                     /gene="fabK"
                     /locus_tag="VYP66_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1849876.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(30488..30712)
                     /locus_tag="VYP66_000257"
     CDS             complement(30488..30712)
                     /locus_tag="VYP66_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1849877.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(30772..31746)
                     /locus_tag="VYP66_000258"
     CDS             complement(30772..31746)
                     /locus_tag="VYP66_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1849878.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(31746..32180)
                     /locus_tag="VYP66_000259"
     CDS             complement(31746..32180)
                     /locus_tag="VYP66_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1849879.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTINVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(32274..33059)
                     /locus_tag="VYP66_000260"
     CDS             complement(32274..33059)
                     /locus_tag="VYP66_000260"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1849880.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            33384..34748
                     /locus_tag="VYP66_000261"
     CDS             33384..34748
                     /locus_tag="VYP66_000261"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1849881.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            34751..35122
                     /locus_tag="VYP66_000262"
     CDS             34751..35122
                     /locus_tag="VYP66_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1849882.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            35336..36610
                     /gene="serS"
                     /locus_tag="VYP66_000263"
     CDS             35336..36610
                     /gene="serS"
                     /locus_tag="VYP66_000263"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1849883.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(36635..37534)
                     /locus_tag="VYP66_000264"
     CDS             complement(36635..37534)
                     /locus_tag="VYP66_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1849884.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(37644..38192)
                     /locus_tag="VYP66_000265"
     CDS             complement(37644..38192)
                     /locus_tag="VYP66_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1849885.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(38410..39732)
                     /locus_tag="VYP66_000266"
     CDS             complement(38410..39732)
                     /locus_tag="VYP66_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1849886.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(39823..39911)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(40075..42411)
                     /locus_tag="VYP66_000267"
     CDS             complement(40075..42411)
                     /locus_tag="VYP66_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1849887.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(42515..43063)
                     /locus_tag="VYP66_000268"
     CDS             complement(42515..43063)
                     /locus_tag="VYP66_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1849888.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(43060..43362)
                     /gene="zapA"
                     /locus_tag="VYP66_000269"
     CDS             complement(43060..43362)
                     /gene="zapA"
                     /locus_tag="VYP66_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1849889.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            43449..44321
                     /locus_tag="VYP66_000270"
     CDS             43449..44321
                     /locus_tag="VYP66_000270"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1849890.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            44333..44947
                     /gene="lepB"
                     /locus_tag="VYP66_000271"
     CDS             44333..44947
                     /gene="lepB"
                     /locus_tag="VYP66_000271"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1849891.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAHAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            45027..45149
                     /locus_tag="VYP66_000272"
     CDS             45027..45149
                     /locus_tag="VYP66_000272"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV1849892.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            45226..47592
                     /locus_tag="VYP66_000273"
     CDS             45226..47592
                     /locus_tag="VYP66_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1849893.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYIFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILDAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(47640..48923)
                     /locus_tag="VYP66_000274"
     CDS             complement(47640..48923)
                     /locus_tag="VYP66_000274"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1849894.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     ATAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(49722..50858)
                     /locus_tag="VYP66_000275"
     CDS             complement(49722..50858)
                     /locus_tag="VYP66_000275"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEV1849895.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFKNPFIADEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(50920..51357)
                     /locus_tag="VYP66_000276"
     CDS             complement(50920..51357)
                     /locus_tag="VYP66_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1849896.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYESGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLAGAQSKEEVLRLFDAVE"
     gene            complement(51359..53314)
                     /locus_tag="VYP66_000277"
     CDS             complement(51359..53314)
                     /locus_tag="VYP66_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1849897.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQTYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTIN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(53338..55107)
                     /locus_tag="VYP66_000278"
     CDS             complement(53338..55107)
                     /locus_tag="VYP66_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEV1849898.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MIMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            55316..56462
                     /locus_tag="VYP66_000279"
                     /pseudo
     CDS             55316..56462
                     /locus_tag="VYP66_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(56590..57612)
                     /gene="cbpF"
                     /locus_tag="VYP66_000280"
     CDS             complement(56590..57612)
                     /gene="cbpF"
                     /locus_tag="VYP66_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HEV1849899.1"
                     /translation="MKLFKKMMQVVLATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(57631..58452)
                     /gene="cbpG"
                     /locus_tag="VYP66_000281"
     CDS             complement(57631..58452)
                     /gene="cbpG"
                     /locus_tag="VYP66_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEV1849900.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKNAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSAVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNRAMVTGSQTIDGKVYNFASSGEWI"
     gene            complement(58533..58772)
                     /locus_tag="VYP66_000282"
     CDS             complement(58533..58772)
                     /locus_tag="VYP66_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849901.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(58922..59188)
                     /locus_tag="VYP66_000283"
                     /pseudo
     CDS             complement(58922..59188)
                     /locus_tag="VYP66_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(59213..59524)
                     /locus_tag="VYP66_000284"
     CDS             complement(59213..59524)
                     /locus_tag="VYP66_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1849902.1"
                     /translation="MDWDFADTCWEKDPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSLWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(59449..59691)
                     /locus_tag="VYP66_000285"
     CDS             complement(59449..59691)
                     /locus_tag="VYP66_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1849903.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(59692..60324)
                     /locus_tag="VYP66_000286"
     CDS             complement(59692..60324)
                     /locus_tag="VYP66_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1849904.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(60338..61333)
                     /locus_tag="VYP66_000287"
     CDS             complement(60338..61333)
                     /locus_tag="VYP66_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1849905.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(61330..62028)
                     /locus_tag="VYP66_000288"
     CDS             complement(61330..62028)
                     /locus_tag="VYP66_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1849906.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(62105..63115)
                     /locus_tag="VYP66_000289"
     CDS             complement(62105..63115)
                     /locus_tag="VYP66_000289"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1849907.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIVDLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            complement(63099..64106)
                     /locus_tag="VYP66_000290"
     CDS             complement(63099..64106)
                     /locus_tag="VYP66_000290"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1849908.1"
                     /translation="MIAVKTCGKLYLAGEYAILEPGRLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLTSSKETVVFLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(64093..65046)
                     /gene="mvaD"
                     /locus_tag="VYP66_000291"
     CDS             complement(64093..65046)
                     /gene="mvaD"
                     /locus_tag="VYP66_000291"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1849909.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(65028..65906)
                     /gene="mvk"
                     /locus_tag="VYP66_000292"
     CDS             complement(65028..65906)
                     /gene="mvk"
                     /locus_tag="VYP66_000292"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1849910.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVS
                     AESPWRLYEEDTLSMAVYASLEYLDITEACVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(66028..66357)
                     /locus_tag="VYP66_000293"
     CDS             complement(66028..66357)
                     /locus_tag="VYP66_000293"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1849911.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
     gene            66881..67843
                     /locus_tag="VYP66_000294"
     CDS             66881..67843
                     /locus_tag="VYP66_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV1849912.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
     gene            67886..69118
                     /locus_tag="VYP66_000295"
     CDS             67886..69118
                     /locus_tag="VYP66_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1849913.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDNLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVTFNTHN"
     gene            complement(69236..70255)
                     /gene="cbpC"
                     /locus_tag="VYP66_000296"
     CDS             complement(69236..70255)
                     /gene="cbpC"
                     /locus_tag="VYP66_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1849914.1"
                     /translation="MKILKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDGGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMVTGWVKDDSTWYYLNAGNGDMKTGWFQVNGRWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(70353..71042)
                     /locus_tag="VYP66_000297"
     CDS             complement(70353..71042)
                     /locus_tag="VYP66_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1849915.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(71054..72478)
                     /gene="gndA"
                     /locus_tag="VYP66_000298"
     CDS             complement(71054..72478)
                     /gene="gndA"
                     /locus_tag="VYP66_000298"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1849916.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(72554..73948)
                     /gene="mapZ"
                     /locus_tag="VYP66_000299"
     CDS             complement(72554..73948)
                     /gene="mapZ"
                     /locus_tag="VYP66_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1849917.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLNQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(73961..75118)
                     /locus_tag="VYP66_000300"
     CDS             complement(73961..75118)
                     /locus_tag="VYP66_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1849918.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(75203..75583)
                     /gene="rnpB"
                     /locus_tag="VYP66_000301"
     ncRNA           complement(75203..75583)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VYP66_000301"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(75604..75933)
                     /gene="gpsB"
                     /locus_tag="VYP66_000302"
     CDS             complement(75604..75933)
                     /gene="gpsB"
                     /locus_tag="VYP66_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1849919.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(76003..76530)
                     /locus_tag="VYP66_000303"
     CDS             complement(76003..76530)
                     /locus_tag="VYP66_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1849920.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVVQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            76596..77192
                     /gene="recU"
                     /locus_tag="VYP66_000304"
     CDS             76596..77192
                     /gene="recU"
                     /locus_tag="VYP66_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1849921.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            77189..79348
                     /locus_tag="VYP66_000305"
     CDS             77189..79348
                     /locus_tag="VYP66_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEV1849922.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(79515..84818)
                     /locus_tag="VYP66_000306"
     CDS             complement(79515..84818)
                     /locus_tag="VYP66_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1849923.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYGNDRTVVSVKTDNQEGVKADDTPAQKETGSVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKIRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTNKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGEGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWIDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKRTALVADD
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKVQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPIVEKPEFKLNSLASEQGKTPDYKQEIA
                     RPETPAQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(85119..87101)
                     /locus_tag="VYP66_000307"
     CDS             complement(85119..87101)
                     /locus_tag="VYP66_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1849924.1"
                     /translation="MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKSKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(87279..87802)
                     /locus_tag="VYP66_000308"
                     /pseudo
     CDS             complement(87279..87802)
                     /locus_tag="VYP66_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170108.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
     gene            complement(87789..88898)
                     /gene="glf"
                     /locus_tag="VYP66_000309"
     CDS             complement(87789..88898)
                     /gene="glf"
                     /locus_tag="VYP66_000309"
                     /EC_number="5.4.99.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
                     /protein_id="HEV1849925.1"
                     /translation="MYDYLIVGAGLSGAIFAYEATKRGKKVKVIDKRNHIGGNIYCEN
                     VEGVNVHKYGAHIFHTSNKKVWDYVNQFAEFNNYVNSPVANYKGSLYNLPFNMNTFYA
                     MWGTKTPQEVKDKITEQTADMKDVEPKNLEEQAIKLIGPDVYEKLIKGYTEKQWGRSA
                     TELPPFIIKRLPVRLTFDNNYFNDRYQGIPIGGYNVIIENMLKDVEVELGVDFFAHRE
                     ELEASAEKVVFTGMIDQYFGYKHGELEYRSLRFDHEILDEENYQGNAVVNYTEREIPY
                     TRIIEHKHFEYGTQAKTVITREYPADWKRGDEPYYPINDEKNNAMFAKYQEEASKNDK
                     VIFCGRLADYKYYDMHVVIERALEVVEKEFGYDKK"
     gene            complement(88912..89910)
                     /locus_tag="VYP66_000310"
     CDS             complement(88912..89910)
                     /locus_tag="VYP66_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEV1849926.1"
                     /translation="MSKFRNINLDLLKVLACVGVVLLHTTMGGFKETGAWNFLTYLYY
                     LGTYSIPLFFMVNGYLLLGKREITYSYILQKIKWLLITVSSWTFIVWLFKRDFTENLI
                     KKIIGSLIQKGYFFQFWFFGALILIYLCLPILRQFLNSKRSYLYSLSLLMTIGLIFEL
                     SNILLQMPIQTYVIQTFRLWTWFFYYLLGGYIAQFTIEEIESRFKNWMKIVSILLLLI
                     SPIILFFIAKTIYHNLFAEYFYDTLFVKVSTLGIFLTILMLTLNENRRESIVSLSNQT
                     MGVFIIHTYIMKVWEKVLGFNFVGAYLLFALFTLSVSFIIVGMLMKIPYFNRIVKL"
     gene            complement(89912..91327)
                     /locus_tag="VYP66_000311"
     CDS             complement(89912..91327)
                     /locus_tag="VYP66_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003009066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase"
                     /protein_id="HEV1849927.1"
                     /translation="MKILKNYAYNLSYQLLVIILPIITTPYVTRVFSSDDLGTYGYFS
                     SIVTYFTLLATLGVANYGTKEISAHRKEIGKNFWGIYSLQFGATWLSILLYLALCFLF
                     TSMQNPVAYILGLSLVSKGLDISWLFQGLEDFRKITVRNITVKLVGAISIFLFVKSAN
                     DLYLYVFLLTIFELLGQLSMWLPARQFIGKSYFDWKYAKKHLKPVILLFLPQIAISLY
                     VTLDRTMLGVLASTKDVGIYDQALKLVNILLTLVTSLGSVMLPRVSSLLSSGDYKAVN
                     KMHEMSFLIYNLVIFPIIAGMLIVNDDFVRFFLGQNFQDARYAIAIMTFRMFFIGWTN
                     IMGIQILIPHNKNKEFMVSTTVPAILSVGLNLLLLPQFGYIGAAIVSVLTEAFVWGIQ
                     LFYTRFYLKEVPIIGSMTKTALASAVMYGLLLGSKTSIHFSPTINVLIFSVLGGIIYL
                     FAILSLKVVDVKELKQIIRKN"
     gene            complement(91358..92581)
                     /locus_tag="VYP66_000312"
     CDS             complement(91358..92581)
                     /locus_tag="VYP66_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1849928.1"
                     /translation="MHVRLDGLLDYIFLFSVIITCNTMYSTSQGFDGLGKWATLLLVV
                     SVFLKLLISRISMKAINVIVSRSLIFILIILLIVILNGFKISETSFVYYFVLFPIFMM
                     ILQMYYDVNEIANLIRKFVRIIFLLAIGSLLFWLIGSVFHIISPTVYVLNYWNGGGIV
                     EGYYNLHFEAQKIEILGAILIRNTGIFAEAPMWSLVLSLALIFQTLHIKKWNFTTWTL
                     IITIMTTTSTTGVYIIGLIFLYVLFSKTSGVKRYVSSLFILAIICCFSILWDNKSGTG
                     SATIRFDDYKAGFLAWQKSPIWGLGISDGLRTIEQHMDRTVRYNLGYSNSFFVVLAQG
                     GIMLASYYFYPVIKIILNKFSSNDLKFSALLIIFLMITTIFIETYMFLFVISLYYSLD
                     FGDDRDCHEKQYITN"
     gene            complement(92582..93553)
                     /locus_tag="VYP66_000313"
     CDS             complement(92582..93553)
                     /locus_tag="VYP66_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1849929.1"
                     /translation="MISVIVPVYNVADYLRFALDSLLEQTYKDFEVILVNDGSTDNSG
                     EICDEYGKLYDNIHVFHKKNGGLSDARNFGLEKSRGEFITFLDSDDYFEPYALELLIT
                     IQKKYDVDIVSTKGGITYSHDIYSKKLMAEDYLTVKILTNKEFLAAVYYNDEMTVSAW
                     GKLYKRDLFKTIFPKGKIYEDLYVVAERLLNIKTVAHTDLPIYHYYQRQGSIVNSTFS
                     DRQYDFFDAIDHNEAIIKKFYCGDKELLAALNAKRVIGSFILSNSAFYNSKNDITKII
                     RIIKPYYWEVIKNKKIPMKRKVQCVLFLLSPNYYYKIKDKMLQRGRI"
     gene            complement(93573..94541)
                     /locus_tag="VYP66_000314"
     CDS             complement(93573..94541)
                     /locus_tag="VYP66_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HEV1849930.1"
                     /translation="MRKIGKVINEYFVLRKSFTPAIARNKLFEKFWGRIGNYKIFNNI
                     ASNFYQYKHETIINFLEKDFSQFLKSYNFKEVSHKEIEQRKIFSMWIQGYESAPKLVQ
                     KTIDSQRKYAEKYGYKFVFLDENNIREYVTLPSEIVEKYENGTIDFIKYSDVVRGTLL
                     SKYGGVWLDSTIYVDSSRELNYLKKDFYTIRAKTHERVPKYIANGRWSAFCLSGEKQN
                     IVFDFLEKFHVAYFMKYDIVLDYFLIDYIIELGYRTNDLIRNYIDKVEENNQELFFLA
                     DNFSNQYDEKEWAGVLSTTALFKCSYKCPINEATGTYFDRLMKGEL"
BASE COUNT        28242 a        21125 c        16996 g        28206 t
ORIGIN      
        1 gctttttgcc gtgctctaaa atcatcgcca aatcatcaaa ttgaaataag aaatagttta
       61 gataaaacta ttgacttttc ttatagtttg tcttttttct atcttccatt atatcatact
      121 ttttcagtct atggtagctc tctttaaaag gcaccgatac tgccgccacc tccgcctcca
      181 gagaagccac caccagaact tccacttcca gaagatacag agtaggtgct tgctgtattt
      241 gcgacactag cataatggct catttgcgcg cttgaatgat aaaacagact gtgccagcca
      301 taagctacat agagattgat atctggattt tccacttgaa tctgatgaac cttcatcaaa
      361 tgactaacct tgtccgcata gccaaataag gtcgcataga ccaagaggcg attccagacc
      421 acaatacttt ccagttcagc ctgatccaat cgtgcaatct cacgcaacat attttcaaaa
      481 ctggtccaga gatagtagac ctcagctccc gcttcattta gaacaccatc acgattatct
      541 agtcgaagct tccaataata gaaaacagac aaaactaacc ctagaaaacc aagtattggc
      601 aaagggaggt aaagatagcc atgaacgtct aaactgtaca agaacaaacc aaatccgata
      661 aataggggca ggatagtcaa ggcacccata cccacttgca aggccttttc cccaccagtt
      721 aaaggacgat aataatctgg gagcccccag aaggaaactc gttttctcac tccttcttgc
      781 atctggttca atacctcttc aaaagaagat ttgagttgaa gccctcttgc ttgaatccgt
      841 ttttcatcag aaactttggc tctacgataa agactatcag ataccttgta atccgcaaac
      901 aaattggaaa gagtttcttc ttttttacct gaaaaagcta gatttaggca gtctttctca
      961 aagcttgaca aaccatcttc ttttactagc ctcaaaccaa ctgcatctcc ttctgaaatg
     1021 atagagacat tcccacggtc tatcacatct agcaaggtag cttgaataag ttgatcaaag
     1081 gtgaattttc cagctccctt gaccaaggga ctcacttcct ccaaggaggt cgagtagact
     1141 gcttctgata aaaccatagg ctctaattcc attggtggtt catagagacg atgatttttg
     1201 gcatatttga ctgaaggagt ggtctttctt ctataaataa aatagaagca gacactcaat
     1261 aacaaggaga tagaaaggat cgaagggagg acccaagtaa caagttgttt actctgatct
     1321 ttttctctaa caatcgagtc ttctatctta ttaaactctt ctaaacgatt ccctttcaat
     1381 ccctgatccc tagcgctagc aaaatcggtc cgaggccaat aggcatgcaa ctcaactcca
     1441 cgcttagccg gaagattgtc taaacggata gtataatcaa ggttactctt ttcaatcgtt
     1501 ccctctctaa aaagtttccc tgtatggaaa aagagttttt cagctccctt gtctcccctt
     1561 acatgaaatt caaacttttc aatagactct gaactatctg tcagaggttg ccaatttaat
     1621 tcagcgatat catcataaag gaaaagtaaa ttttttaagt tccagacgag gtcaacttca
     1681 actatgtcgc cctcctgacc tggattatag actctcacag tataaccatc cgcttcttct
     1741 gttacttcgc tagtcacatc tgctagttct gcaccgtttt tcgcggcctg aacctttgga
     1801 tgagggtcaa tgtcaaaccc gctaggcatc ttaccagcac gtccaagtcc cacgatttgt
     1861 cccttaaagt cctcctcaaa ctggtaaact atcttctgtc taaactctgc cgtattatct
     1921 gcatgaatat acaaatcccc ttgataagag tttatcttga aatcaatggc aaaaacagag
     1981 agtggaagaa ggcaaaacaa gcctaacacc agtaagaaaa aagttttttt catcaactaa
     2041 gccccctttt tatctttctt atcattatag cattttttcg taagtaaagg cttacttatg
     2101 ttgaaaaatt acgcattttt cgataaaata ggagacagtt attttttaat agatcagaat
     2161 aggagaaatc atgagaaaaa tatacttatc tattttcaca agtctcttgc tgatgctagg
     2221 acttgtcaat gttgctcaag ccgatgaata tttacgcatc gggatggaag cagcatatgc
     2281 tccctttaac tggacccagg atgatgatag caacggagct gtcaaaatcg atgggaccaa
     2341 tcagtatgcc aacggatacg atgttcaaat cgccaagaaa atcgctaagg acttaggtaa
     2401 aaaacctttg gttgttaaaa ccaagtggga aggtctagtc cctgccctta cttctggtaa
     2461 gattgacatg attatcgcag gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt
     2521 ttcgagcagt tactacacta gcgaaccagt tttgcttgtc aaaaaagatt ctgcctacgc
     2581 aagtgctaaa tctttggatg actttaacgg tgcaaaaatc acttctcaac aaggggtcta
     2641 cctctacgac ttgattgcac aaatcccagg tgctaaaaaa gaaacagcca tgggagactt
     2701 cgctcaaatg cgacaagctc ttgaggctgg tgtcattgat gcttatgttt ctgaacgtcc
     2761 agaagcactg actgctgaag ctgcgaactc taagttcaag atgattcaag tagaacctgg
     2821 tttcaaaact ggggaagaag atacagctat cgctatcggg cttcgtaaaa atgacaatcg
     2881 tattagccaa atcaatgcca gcattgaaac catttcaaaa gatgaccaag ttgccttgat
     2941 ggatcgtatg atcaaggaac aacctgccga agctacaaca actgaagaga ctagcagtag
     3001 tttctttagc caagtcgcta aaattctttc tgaaaactgg caacaactct tgcgtggtgc
     3061 tggtatcact cttttaatct ctatcgtcgg aaccatcata ggtctcatta ttggacttgc
     3121 cattggtgtc ttccgtactg ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa
     3181 actagtcggc tgggttctca atgtctacat tgaaattttc cgtggtacgc caatgattgt
     3241 tcaatcgatg gttatctact atggaactgc ccaagctttc ggtatcaacc ttgaccgtac
     3301 actagctgct atcttcatcg tttcaatcaa taccggtgcc tacatgactg aaattgtccg
     3361 tggtggtatc ctggcagttg acaagggaca atttgaagct gcgactgctc ttggtatgac
     3421 tcataaccaa accatgtgta agattgtcct acctcaggtt gtccgcaata tcctaccagc
     3481 aactggtaat gaatttgtca tcaatatcaa agatacatct gtattgaacg ttatctctgt
     3541 tgtcgaactt tatttctcag gaaataccgt ggcaacacaa acctatcaat acttccagac
     3601 atttacaatc atcgccgtga tttactttgt cctcaccttc accgtaacac gtatcctacg
     3661 ctttatcgag cgcagaatgg acatggatac ctacactaca ggtgctaacc aaatgcaaac
     3721 ggaggatttg aaataatgac acaagcaatc cttgaaatta aacacctcaa aaaatcctat
     3781 ggacaaaacg aagtgctaaa agacatttct ctcactgtcc acaagggaga agttatttct
     3841 atcatcggaa gctctggaag tgggaaatca accttcctac gctccattaa cctacttgaa
     3901 acgccaactg atggacaaat cctttatcat ggacaaaacg tcctcgaaaa aggctatgac
     3961 ctcacgcaat accgtgaaaa gttagggatg gttttccaat cctttaacct ctttgaaaat
     4021 ctcaacgttc ttgaaaacac aatcgtcgct cagacaactg tccttaaacg cgaacgcaca
     4081 gaagctgaag aaattgccaa agaaaacctg gaaaaggtcg gcatgggaga acgctactgg
     4141 caagcgagac ccaaacaact ctcaggtggt caaaaacaac gtgtggccat cgctcgtgcc
     4201 ctttcaatga atcctgacgc cattctcttt gatgaaccaa catcagctct cgatccagaa
     4261 atggttggag aggtcctcaa aatcatgcaa gatctggctc aggaaggctt gaccatgatt
     4321 gtcgtaaccc atgaaatgga atttgcccgt gatgtctctc accgtgttat ctttatggat
     4381 aagggtgtga ttgctgaaga aggtaaacca gaagacctct tcactaatcc taaagaagac
     4441 cgtacaaaag aatttcttca acgttatctc atactcaatg aaaatcaaag agcaaactag
     4501 gcagctagcc gcaggttgct caaaacactg ttttgaggtt gcagatagag ctgacgtggt
     4561 ttgaagagat tttcgaagag tatcaaataa aaagaaaagg ctgcatcaac cgtgcagtct
     4621 ttttgctgtc ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa
     4681 tccaccgtta tccaaagatt aatcttcaaa tttttcatga tttttttcat agaaatcaat
     4741 taagcctagg gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc
     4801 aatgatagac atttcacgcg cattcgtttc tttagagata cggtagcctg tgattttctt
     4861 atcacgaacc cagccaacaa ctgattctac tttttcaaag tttgacttag ccatgttttt
     4921 ctcctatttt cttctttata atatttaatt gtatacgttt ttactacttt tgtcaataaa
     4981 aaaaacatat attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc
     5041 gataatatat aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta
     5101 ttattaccct cttaaggtgc aaaattattc aagttcttaa aaaatgcttc tctatttccg
     5161 taagatagct tatttcttcg atttaagaac tgaagatgat agttctaacc tttagaaatc
     5221 caagccttct ctagctcaaa aactcctatc tttcttcctc aataaatcat ctgagagata
     5281 ggtattcctt atatccttca aattcatcac tcctttggat attgaggtgc tagcctagaa
     5341 gcagacaccc gattatctaa accatcctta atagagatga caagacagat aagctcagtt
     5401 aattacttat atatcttttt aatatggtat atttgtcaac aaaaagaaat caaatcatac
     5461 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaaatt gctcaaaaca
     5521 ctgttttgag gtttcagata gagctaacgt ggtttgaaga gattttcgaa gagtattaaa
     5581 gacagtatga ctatgcttgt caatagatag gaaatcaaaa tgaaggatgg aaatctgagc
     5641 caaacatcat aagtgctata atgaacagaa gtaagaattg cacgataagt tttctaaaac
     5701 cataggaatc gtcccctttc ttcatcttca ttatagcaca tatacatcag ttgtacaaat
     5761 aatatgatat ttttttatta gtcctcagac aagcatatta taaagcgttt cattaccatt
     5821 taagttaata taagctggat caaaaccttc cattctacgg atcaaacctg cataatcatg
     5881 cttatctgcc aaagcgatcc caatcaatac tgggcctgtt cccttgctag ctcgtttgat
     5941 atactcaaaa cgtgtgatat catcatttgg ccccaggata tcatttacaa actcacgcaa
     6001 agctcctgga cgctgtggga aattgaccac aaagtaatgt ttgataccat cataaatcaa
     6061 ggcacgctct tccatttctg gcatacggtt gatatcatta tttcctccag aaatgataca
     6121 acaaatggtt ttccccttaa tatattcagc taaaacctct aaagaggcga tactagccgc
     6181 tccagcaggt tctgcgacta tcccttgctt agagtaaagg tcaatcaagg tttcagaaat
     6241 caatccctca tcgacaccta ccaaagtttg aatatgttga cgagttgctt cataggtcaa
     6301 ctgacctacc ttttgcacag caatcccatc cgcaaattta tcaatttcct tgagtttgac
     6361 tggacctcca gcctcaaagg cagctttcat ggaacgcgct ccattcgcct ctactccgat
     6421 aacctcaatc tctggacttg tttccttgat ataggtagaa accccggcaa tgagaccgcc
     6481 accaccaaca ggaaccaaga cagcatcaaa atcaatcgat tcttttcgag cttcttctaa
     6541 aatctcataa gcaactgttc cttgacctgc ttgaacatga gcatcatcaa aaggatcaat
     6601 aaaggtacga ttttcagaga ctgtaaattc ttgagctgct ttggctgagg catcaaaggt
     6661 atctccaact agtttaatag ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt
     6721 ttgttgtggc gtagtaatag gcataaagat agtagcagga attttcattt cattacaagt
     6781 ataggctact ccctgcgcat gatttcccgc agaagcgcag actaccccac gttcacgttc
     6841 ttccttgctg agctgggaaa tggcataata ggcaccacga attttaaagg agcgaacacg
     6901 ctgggcattt tcttttttca aataaatctt agcaccatac ttctccgata aataatgatc
     6961 gtaatccagt ggagtattca caaccacacc gttcaagacc ttgtgagcct tgattatatc
     7021 ttttgaactt aacatataaa acctcttttt ctataaaaaa cagtcactaa tgactgtttt
     7081 ttagttattc atctccgaaa acttcagtaa cactttcatg gtatttatga gccatacgaa
     7141 tcgaaaactc tttaggaagt tcataacgat ttgtggaaat ccaatcatat aaccattcta
     7201 ccaaactttc ttcactatca ttacgatgga agataaaata gtttaaaatt tctttatatt
     7261 ctacatcatt caaatccaac gtgtctacaa attgactacg aggaacaaaa ttagaatcta
     7321 attttcttag ttgatctgtc aattctccca attgtaaatc caactgaaaa aatagttttt
     7381 gcagttgcct atcagtttca tcacatcctg tcttgataga aaacaaattg gtaatattca
     7441 tatgatttca acccctaaat aagtacatct aatatcccac gaatagctga agctaaagtt
     7501 ttcgcagtcc agtcatttaa acccgattct ttcaatccag atgcaataat ttgctctatt
     7561 tgatataaac cgccatctat cgtctcattt attctgcgaa gaggaccttc aatataggat
     7621 aaagcttctc cgaatctaac agctgattta ggtcctaatg atttaccaac tatatttgtt
     7681 aatgtttttt atttctcaaa atccatttcg ctatataacg agcagattta gtcgcaccag
     7741 ctctctcaaa cggagaatga atttcaagac cttcttctct agctatttgt gccaatttga
     7801 agaattgttc aaaggtcata tgcaacctac catcttcaaa attagcatca tcataaatgt
     7861 taattacagc attttcatca tacgaccaat ctgctttatt ttggtctgct agcactatta
     7921 ccgacggtgt aattacatta tacaactaga accaataata acgatgcaat ttttctcata
     7981 atctttttca taaaatcatc tccagcgcta tatatttcta attagttata gattttgaat
     8041 gcatcatcgt cgtttttacc aacaaatggc attgctttac gcaattctgc accaactttt
     8101 tcaatttcaa ggttagctgc ttgttcacgg taagcagtca attttggacg tccagcttta
     8161 tagtcattta caaagtcatt tgcaaattta ccattttgga tgtctgccaa gacagccttc
     8221 atattttctt taacttgttc agtgattaca cgtggacctg atacatagtc accgtattca
     8281 gcagtgtttg aaatagattg acgcattttc ttgaatccac cttcgtagat caagtcaacg
     8341 atcaatttca tttcgtgaag aacttcaaag taagccaatt ctggagcgta acctgcttct
     8401 gtcaagactt cgaaacctgc ttcgataagg gcagtcaaac caccacaaag tacagcttgt
     8461 tcaccaaaca aatcttcttc agtttcttct ttgtaagttg tttcaagaag acctacacga
     8521 gccgctccaa cacctttaca ccagtccata gcaatgtttt tagcatttcc tgttgcatct
     8581 tggtatactg cataaagagc tggaacacca aatccttctt cgtaagtacg acgtaccaag
     8641 tgtcccggtc ctttaggagc acacatgaag acatctacat ccgcaggaac tttgataaat
     8701 tcaaagtgga tgttgaaacc atgggcaaat ccaactgcgt ttccagcttc caagtttgga
     8761 gcgatttctg cttcgtacaa ttcttgttga atttcgtctg gcgccaagat catgataaca
     8821 tcagccaact tagtagcttc tactactgtg taagtatcaa atccatcttc ttttgcttta
     8881 tcaaaagatt tacctggacg tacaccgata ataacgtcac gacctgaatc acgcaagttt
     8941 tgagcatgcg catgtccttg tgaaccataa ccgataacgg cgattttttt accgtcaagt
     9001 gctgctactt taacatcttt ttcatattcc atttgaactg tcatagcttt tctctctttt
     9061 ctattattta ttgcctttta ggctggttta ataaatttaa gttggatttt taatcgcggg
     9121 taaatccagt tgcacccgtt cgagcaatat tgcgaatacc gtatgggcga atgactcgca
     9181 atagggcttc gctcttttct gcatttcccg tcatctgaat ggtaatcgag cttggcgcta
     9241 cgtctaccac tgttgcacgg aaaggttgaa taatcgctaa aatctcagct ctcttctcag
     9301 ctggcgctga catcttaacc aaaatcacct cgcgctccaa atgaggcttg tctgtaatat
     9361 ctcgaatgcg aatcacatca atctgacgat tgagctgttt gatgatttgc tccacttcat
     9421 catgagaagc aacatcaata ataatagtga tacgcgatac attcggatct tctgttgctc
     9481 caacagagat gctttcaata ttaacctgac gacgagatag gacacctgta aagcgattga
     9541 ggactcctga acgattttgt agttttgctg ttaacattct acgcatggaa ctgcaccccc
     9601 aacatctcat gattactctt accagccggt accattggta acacctgttc cttacgagaa
     9661 atatctacct caattagcat aggaacatcc tcagtgatga cttcaaggtc ttgagccaag
     9721 gtctcaggat tgtcaaactt atagttttta ataccataag cctgcgccat caattggaaa
     9781 tcaggaaggg tatcaaagac cgactctgat gttctgcctt catagaagga ttcctgccac
     9841 tggcgaacca ttccaagtga atgattgttc agcataacca ccttgattgg caccttgtaa
     9901 atattcaaaa tagccaactc ctggttggtc atttggaaac caccatcccc aacaaacaag
     9961 actacttcct tatctgggtt agcaatttta gcaccgattg ctgctggaat tccaaagccc
    10021 attgttccca aaccacctga agtcactaac tgacgctcat tttggtaggg ataatactga
    10081 gctgtccaca tttggtgttg accaacgtct gttaccacaa tggcatctcc attcgtcaat
    10141 tcaccaattc gttcaataac tgcttgcggt tgaaccacac gctctttctt gtcataagaa
    10201 cgaacacgat tcttgtcttt agtgactttc tcaatccact tttcagtatt gttgtgaact
    10261 gttggttctg ctagcaacat ttgcaaggcc ttcttagcat ctccaactac aggaatgtct
    10321 gcactgataa tcttgccaat ctcagctggg tcaatatcaa tgtgggcaac cttagcattc
    10381 ttagcgaaag tcttaggatt ccccgtcaaa cggtcatcga aacgagaacc aatactaatc
    10441 ataaagtccg cttccgtcat ggcaatattt gctgcgaatg acccgtgcat gcctcccatt
    10501 ccaagaaaga gtgggtgact cgttgcaatc gttccttgtc ccaaaagact ggttaccact
    10561 ggaatttgat agcgttctgc aaattcattt agttccgtag cagcctcagc ataactaatt
    10621 ccaccaccag ctaacaagac tggcttttta gccttggaca attgcttcaa gattttcttg
    10681 atttgcatat cattcggctc aagagtcggc tgataacttg gtaaattcac ttctggtgaa
    10741 taaatgaagt ctgtttctaa agcagatatg tcttttggta ggtcaattac aactggccct
    10801 ggacggcctg tagttgcgat atggacagct tccgtaatga tacgcggaat atcagctgtc
    10861 tcacgaactt ggtaattgta cttagtgatt ggcatggtaa ttcctacgat gtctgcctcc
    10921 tgaaaggcat ccttcccaat ccctgctcgc gccacctgac ctgtaaagac caaaagggga
    10981 acgctatcgc tcatagcatc cgcaatccct gtaatggcat ttgttgctcc tggtccacta
    11041 gtgacgacgg caacacccaa ctttccagtt gatttggcat aaccttcagc ttcatgcaaa
    11101 caaccttgct catggcgccc tagaatgtgg cgaatgcctt taaaattata tatcgcatca
    11161 taaaaaggca aaaccgcacc accaggataa ccaaagatgg tatcaactcc taaatcacga
    11221 agtgtttcca aaactaggtc cgaccccgtc ttaggagatt ctaaactgat tttctccatt
    11281 gttccccttt ctttcctctt aaaaataact tgttactatc ataccatttt ttcaaaattt
    11341 ttcaagataa aagaagaaat tttctgaatt ttctatttta acgtttattt atgaatgtta
    11401 tttttgtttt tattaaaaag ataccgattt catttactaa aaaagaaaaa agaactgatt
    11461 tctcagtcct tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac
    11521 cttggtgaat ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat
    11581 tggcaagttc ttcgcttccg tcttcaccga catagaaggt tacgatttca ctatcttcat
    11641 ccaacatatg tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa
    11701 tttttccatc caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg
    11761 tatcacgcac ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac
    11821 gctcttggtt ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt
    11881 gaggaagagt gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt
    11941 gagctgccat gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct
    12001 gttcaacagc cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa
    12061 cataatccac gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa
    12121 tcaaagcata ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct
    12181 gtgcttcgtg ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga
    12241 gaccttcttg cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat
    12301 catcgttaac aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt
    12361 agtcaaaatc tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt
    12421 aaccaaacgt gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat
    12481 tgatcatctc actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc
    12541 cagtaagggc tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca
    12601 caacgccaac ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag
    12661 caccttccaa ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct
    12721 tagcaccgat agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca
    12781 ctgccttata ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta
    12841 actcgtcttt atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc
    12901 ctgagttccc acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa
    12961 ctgtagaagc tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat
    13021 ttgtcccagt atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt
    13081 gcttattcaa gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt
    13141 ttgacacggt tattctccta caactttgat attttgaatg tagacattta cagtctgagc
    13201 agtaattcca agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac
    13261 ttcactaatc tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc
    13321 ttcggctgcc tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa
    13381 attatctttg agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc
    13441 tccacctacg acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt
    13501 aatttttaca gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag
    13561 cccaagtgta aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt
    13621 tatacccaca ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg
    13681 ttcaacttta cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc
    13741 gataagaaca gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc
    13801 gtgtgaacgg ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat
    13861 tgtgttttcc tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat
    13921 gttatcacac tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa
    13981 tcaggtcttg cgtgacattt tctgctctcc acatgccatc gttgattaac agaacaccag
    14041 aattaaaatt atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt
    14101 ccaaatccca cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta
    14161 cacgagactc gcttacatac tttggaataa aatacctaaa aaagccgcat atgaaagtcc
    14221 ctcaaagggg agacgataac ctttcagaat actactgtca atctaaacat tcacaatctc
    14281 actattcaaa gtctctagtc ttttttccat taattggaac cattctcgcg gaaggtcatc
    14341 attaaaaaca taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc
    14401 aactttatcc atataagcat tatctgcacc taagacaatc gcttttttct cttctttcac
    14461 tttttatctc atttcttttt attcccatca tatgtttcta cgtaaccatt attttcgcct
    14521 attcgttcgt aaaaccatac cagtggagat tttagatgaa gtcccattac ggtttacaat
    14581 ttttacatta cgacacagag ttttacaaat cgatttcatt tgccaaacgt agttagtaag
    14641 gcagttagct aggctaccta ctttctgcta cgacggaaaa atccacaaat caataccatt
    14701 cgtggatttt tcctagtgaa gcgtttaggt aagccgccat agcggttacc gattattaga
    14761 ttacgacacg gagtttggca aatcgattct atttgccaaa cgtagttagt gaggcagtta
    14821 gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc caattgttgg
    14881 tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca aaccagcgga
    14941 gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg gctaagatat
    15001 tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga acggtctttt
    15061 tacccattgg gctcatgacc acttccgcat tgtattcgcc ttccatacgg tgtttaaaga
    15121 cttcaaactg gagttgacca acagctccca gcatgtactc acctgtttgg taattcttat
    15181 aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag gatttttgct
    15241 tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt ggcaatggtt
    15301 caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa gtaccggtat
    15361 cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga ctctccgcca
    15421 taaactgggt aacattagat agtttagccc ccttaccagt acgagggaga ttgacactca
    15481 tgccgcgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca cggtgacgag
    15541 gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca taaggatcca
    15601 caatttcacc atctgttttc ttgtgaccat gtggttctgg agcaaacttg aggaagattt
    15661 caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt
    15721 ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa agctcaatgt
    15781 catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca tcttctaggc
    15841 tagcaaaacg ctcatcccct ttataaagtt ctaaacgttg gttatagagg tcatacaagc
    15901 cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca atgcccaaga
    15961 tttcttccaa ttcttgcaag agttccaaag gctcacgacc gtcacggtcc agcttgttca
    16021 taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc ttggtttgag
    16081 cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc atcaaggtac
    16141 gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc
    16201 cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc ttctcgatat
    16261 ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta ccagcctcac
    16321 gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc gcgtccgggt
    16381 gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc ataagttctc
    16441 tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta cattggattt
    16501 taccattcct ttcaatactc cattatatcg gattttagca tttttttcaa tttctatttc
    16561 ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca gactaaaaat
    16621 catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac acacgttgcc
    16681 aatctttcaa aattaagatt ctctgaagaa gaaactgctg cctttgcgac caccttgtct
    16741 aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt cgcacctact
    16801 acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga aggaatagac
    16861 cgtgatcgct tgtttaaaaa cgtacctgaa aaagacaact actatatcaa ggtgccagct
    16921 atcctagaca atggaggaga tgcctaatga cttttaacaa taaaactatt gaagagttgc
    16981 acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca acacttgaaa
    17041 atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag gagcaagctc
    17101 ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc ctttcaggaa
    17161 ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact gctgcctcaa
    17221 aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat gcaaaaacca
    17281 agggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt ggttcaggtg
    17341 aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt cctggtgggt
    17401 catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttgtca cttggttctg
    17461 atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa
    17521 cctacggaac agtttcacgt ttcggtctca ttgcctttgg cagctcatta gaccagattg
    17581 gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt gccagcgaag
    17641 atgctaaaga ctctacttct gctcatgtcc gcatcgccga ctttacttca aaaatcggcc
    17701 aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa ggaattaacc
    17761 cagaggttaa ggaaaccatt caaagtgccg ctaaacactt tgaaaaactt ggtgctattg
    17821 tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac atcatcgctt
    17881 catcagaagc ttcatcaaac ttgcaacgct ttgacggtat ccgttacggc tatcgcgcag
    17941 aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggc tttggtgaag
    18001 aggtaaaacg tcgtatcatg ctgggtactt tcagtctttc atcaggttac tatgatgcct
    18061 actacaaaaa ggctggtcaa gtccgtaccc tcatcattca agatttcgaa aaagtcttcg
    18121 cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac ttggactcac
    18181 tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct gtaaacttgg
    18241 caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct gtcggactcc
    18301 aattgattgg tcccaagtac tctgaggaaa ccatttacca agttgctgct gcttttgaag
    18361 caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac taatgaactt
    18421 tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa aaatcttctc
    18481 acctacttct gcccacttcg gaaatgatca aaatgccaac actaacgtga ttgactggtc
    18541 tttcccagga gttctgccag ttctcaataa aggggttgtc gatgccggaa tcaaggctgc
    18601 tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga actacttcta
    18661 tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg gatataatgg
    18721 ctggattgaa gtcgaactag aagacggtac gaccaagaaa atcggtatcg aacgtgccca
    18781 cctagaggaa gacgctggta aaaacaccca tggtacagac ggctactctt atgttgacct
    18841 caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc gttctcctga
    18901 agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg gcatttctga
    18961 cgttaagatg gaagaaggtt ctatgcgtgt ggatgccaac atctcccttc gcccttatgg
    19021 tcaagaaaaa ttcggtacca agactgaatt gaagaacctc aactccttct caaacgttcg
    19081 taaaggtctt gaatacgaag tccaacgcca ggctgaaatt cttcgctcag gtggtcaaat
    19141 ccgccaagaa acacgccgtt acgatgaagc gaataaagca accattctca tgcgtgtcaa
    19201 ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct ttgaaatttc
    19261 tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag aacgtcgtgc
    19321 gcgttatgta tctgaccttg gtttatcaga ctacgatgct agtcagttga ctgctaataa
    19381 agtcacttct gatttctttg aaaaagctgt tgccctagat ggtgatgcca aacaagtctc
    19441 taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca
    19501 aatcgaattg acaccagaaa acttggttga aatgattgcc atcatcgaag acggtactat
    19561 ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg
    19621 tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct tgatcccaat
    19681 catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt caggcaaacg
    19741 taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc aagccaaccc
    19801 acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa actagacaga
    19861 acaaaaccag ccctaaggtt ggttttttct tctctaccaa ctcccaataa ctattttggc
    19921 tttatttcca gagtatttta tggtaaaatg aagagtaata atatttatta aagaggtaaa
    19981 aacatgattg aagcaagtaa attaaaagct ggtatgacct ttgaaacagc tgacggcaaa
    20041 ttgattcgcg ttttggaagc tagtcaccac aaaccaggta aaggaaacac gatcatgcgt
    20101 atgaaattgc gtgatgtccg tactggttct acatttgaca caagctaccg tccagaggaa
    20161 aaatttgaac aagctattat cgagactgtc ccagctcaat acttgtacaa aatggatgac
    20221 acagcatact tcatgaatac agaaacttac gaccaatacg aaatccctgt agtcaatgtt
    20281 gaaaacgaat tgctttacat ccttgaaaac tctgatgtga aaatccaatt ctacggaact
    20341 gaagtgatcg gtgtcaccgt tcctactact gttgagttga cagttgctga aactcaacca
    20401 tctatcaaag gtgctactgt tacaggttct ggtaaaccag caacgatgga aactggactt
    20461 gtcgtaaacg ttccagactt catcgaagca ggacaaaaac tcgttatcaa cactgcagaa
    20521 ggaacttacg tttctcgtgc ctaatctcta gaaagaggtc attctatggg aattgaagaa
    20581 caacttggcg aaatcgttat cgccccacgt gtacttgaaa aaatcattgc tatcgctact
    20641 gcaaaggtag agggtgttca ctctttttca aacagatcag tgtctgatac cctttcaaaa
    20701 ctttcactcg gccgtggcat ttatcttaaa aacgtggacg aagaactcac agcagatatc
    20761 tatctctacc ttgagtacgg agtaaaagtt cctaaggtag cggttgctat ccagaaagct
    20821 gtcaaagatg ccgtccgtaa tatggctgat gtagaactcg ctgctatcaa tattcacgtt
    20881 gcaggtatcg tcccagataa aacaccaaaa ccagaattga aagatctatt tgacgaggac
    20941 ttcctcaatg actagtccac tattagaatc tagacgccaa ctccgtaaat gcgcttttca
    21001 agctctcatg agccttgagt tcggtacgga tgtcgaaact gcttgtcgtt tcgcctatac
    21061 tcatgatcgt gaagatacgg atgtacaact tccagccttt ttgatagacc tcgtttctgg
    21121 tgttcaagct aaaaaggaag aactagataa gcaaatcact cagcatttaa aagcaggttg
    21181 gaccattgaa cgcttaacgc tcgtggagag aaacctcctt cgcttgggag tctttgaaat
    21241 cacttcattt gacactcctc agctggttgc tgttaatgaa gctatcgagc ttgcaaagga
    21301 cttctccgat caaaaatctg cccgttttat caatggactg ctcagccagt ttgtaacaga
    21361 agaacaataa aaagaaaaag tgtttgatag atatcaaaca cttttttctt tgcctcccac
    21421 tatctaaaaa aatgataata gatataattg taaacaaaaa tccagatagg ttttgcatga
    21481 ttgagaaagt taaaaaaact atggcagaga atcgttaatc tcagattgtc ggtagaacga
    21541 taaacaaggg caaaaaagaa accaatcaga ctataatata ataaactaat tggatctctg
    21601 tgagatagta tcaaatggct aatcccaaag atgatagcag ataggataac atccaaatag
    21661 tacttggact agggaaagaa ggtattcata aaataccctc tatcaagagt ctcctcaaaa
    21721 acaggaccga tgattacagg caggacaaaa gataagatag tcgataaaaa ggttggttgt
    21781 ccatttgaaa aaagcacggt aaaatactca tcatgaatat tcctatgatt aatcaaatga
    21841 gcatagcgtg cccaaaaatt accgagaatc tgataaacca cataagttgc aaataagtag
    21901 aagacaaatg accagttcca gctctttttc tcaaagataa agagcatctt tttctttttt
    21961 aacctccaaa ttaatagaag gaaacttccc actaatccca ttgttaaaat aagagaatag
    22021 acatcagctc ctaaccctaa aatgatcgtc acatacaatc caattgtttg tggtaaatag
    22081 gtagatagta aaataataag caaaaatatt ccaaattgtc ttagtttttt tgtgtttctc
    22141 atcgtacttt tttgaaagat taccctgctc ggaagccgta cttccaagca tctatataag
    22201 aattaagtgc cccttgcctc atatagggag caaattctct ataatataac catctactat
    22261 atccatcttc ccaaacagca agaccacctg aagtttgctc caagtcctca gttgaaagaa
    22321 ctgtaaatgt atttgtacct gtcattgcaa gtaccttctt aaaatagatt gttgtaggct
    22381 cacatttttt atagtatatt tctttttttg tctattttat agcccatctc ctcaactggc
    22441 aatttttcga cctgaattac atttttccat aaaaaatgag acctttctag tctcatttag
    22501 tcattcttag tattttctaa atcgttgata gcgttcttcc agcaactctt ctagcggttt
    22561 ttgtgaaagt ctagccagct ccgtttggag ttcttttttg acactcttaa tcagttcttt
    22621 actagaaagt cctatttcag aaatcacctt atccaccacg tccatttcta acagttcatg
    22681 cgaagtgatt ttcatcagtt ctgctgcttc catggcgcga gtaccgtcct tccataaaat
    22741 ggaagcaaag ccttctggac tgagaatggc atagatagaa ttttccagca tccagacacg
    22801 gtccgcgaca gctagagcca gagccccgcc tgaaccacct tcaccgataa taatggcgat
    22861 aataggaact ttcaggtcac tcatttccat gagattgcga gcgatagctt ccccttgacc
    22921 acgttcttct gctccgacac caggataagc acctgctgta ttaataaagg tcacaactgg
    22981 acggccaaat ttctcagcct gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg
    23041 tggttggcca aaattccgtt tgaggttgtc ttgcaaactc ttgccttttt ggataccaac
    23101 aactgttaca gcttggtctc caagccaacc aataccacca acaactgcac catcatcacg
    23161 aaaagaacgg tcaccatgta attggataaa ttcatcaaaa atgcctgtcg caaagtccaa
    23221 ggttgtcaag cgactctgct cacgcgcttc tctgactatt tttgcaatat tcatctagga
    23281 ctccctccat gcaatctgac taggctagca atcgtatctg gtaagtctct tcttttgaca
    23341 atagcatcca caaagccatg ttctaatagg aattctgcct tttggaaatc ctcaggcaag
    23401 ctttcacgaa ccgtattttc aatcacacga cgcccagcaa aaccaaccaa gctctgtggt
    23461 tcagccagaa tgatatcgcc ttccatagcg aaagaagctg tcacaccacc agtcgttgga
    23521 tctgtcaaaa tggtcaggta aaagagacca gcatttgaat gacgtttaac cgccgcagag
    23581 atcttagcca tctgcatgag actcatgatt ccttcctgca tacgggctcc accagaggct
    23641 gtgaatagga caactggcaa tttttcgaca gtcgcatact caaacaaacg agtgattttt
    23701 tcacctacaa ccgtacccat agaagccatg ataaagttag aatccataat cccaagagcc
    23761 acagtctgac ctttaataag agcagttcct gtcacaacgg cttcatgcag acctgttttt
    23821 tcacgcatag atgccagttt cttttggtaa ccagggaaat gcaagggatc cttgctttca
    23881 atccctgtaa acaattcttt gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg
    23941 gcagaaatac gaaaggtata gctacagtgc ggacagatac gttcacttcc cagatccttc
    24001 tgatagatgg tatgcttaca gcctggacac tgggaaaata attcatctgg aacctctggc
    24061 ttagcttgag gtttttccct aaccgaacga ttgggattga ttcgaatata cttatctttt
    24121 ttactaaata gagccattga ttcccctttt cggtttaaac tcttaaagtc attttattct
    24181 ttttcttgat atttaggtaa gaaggtttcc atcaagaagg aagtatcata atccccagca
    24241 atgacattgc gatctgaaat gaggtcaagc tggaaatctg cattggtctg cactccttca
    24301 atctctaatt catagagggc acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg
    24361 tgtactatga ttttggcaat catactatca taataaggcg gaatggtata acctggataa
    24421 actgctgaat ccacgcgcaa gccaactcca ccacttggca gatagagatt agtaatctta
    24481 cctggacttg gagcaaagtt aaaggctggg ttttctgcat tgatacgaca ctcgatggca
    24541 tgaccgcgta ggacaatatc ttcttgctta acagacaaag gctgacctgc cgcaatgcaa
    24601 atctgttcct taacgatatc aacacctgaa acaaactctg ttactggatg ttctacctga
    24661 acacgagtat tcatctccat gaaatagaaa ttgctacttg cttcatcaag aagaaattca
    24721 atggttcctg cattctcata gccaacaaac tctgccgctc gaacagcagc agcacctatt
    24781 tcatgacgca gcgtttttcc gattgcaatc gagggacttt cttccaaaac cttttggtta
    24841 ttcctttgaa gagaacaatc ccgctcaccc aagtgaatca catgtccatg ctcatcacct
    24901 aggatttgaa cctcaatgtg ccgagctgga tagataaccc gttctatgta catggcacca
    24961 ttgccataat tggccttggc ctcactagag gcagtttcaa aggcagaaac gaggtcatct
    25021 ggtttttcaa ccttacgaat ccctttacca cctccacctg ctgaagcctt gagcataaca
    25081 ggatagccaa ttttttcagc aacaatcaaa gcttcttcag agttatgcac ttctccatct
    25141 gaacctggta taacaggcac acctgcttta atcatctgag cacgcgcatt gatcttatcc
    25201 cccatcatat ccataacatg accagatgga ccgataaact tgatacctac ttcttcacac
    25261 atggtcgcaa atttggaatt ttcactgaga aatccaaaac cagggtgaat agcttctgcc
    25321 tcagtcaaga ctgcagctga tagaactgca ttaatattga gataagactc tgttgccttg
    25381 ccaggaccaa tacaaactgc ttcatctgcc aaaagcgtat gaagagcttc cttatcagca
    25441 gttgaataaa ccgctaccgt cgcaatcccc aattcacgtg ccgcacggat aatacgaacc
    25501 gcaatttcac cacgattggc aattaaaatt tttcgaaaca tggagaacct ccttagttcc
    25561 caattgcaaa agtaaggata ccactggctg caagcttgcc atccacttca gcctttgctt
    25621 caaccacagc tatggtgcca cgacgtttta caaaagtcgc tgtcataacc aattggtcgc
    25681 ctggtacaac ttgcttcttg aacttaacct tgtccatacc agcgtaaaag accagttttc
    25741 ctttattttc aggttttgat aactccaaca caccagcagt ttgcgccaag gcttccataa
    25801 tcagaacacc tggcataact gggtattgag gaaagtggcc gttaaagaaa ggttcgttaa
    25861 tggtcacatt tttgatagca acaatggtat cctcgctcac ttccaagaca cggtccacta
    25921 gaagcatagg ataacggtgg ggaagagctt ctttgattcc ttgaatatcg atcatttgat
    25981 acgtaccaat cctttaccaa actcaaccat ttcttcgtta gagacgagaa tttccgttac
    26041 cacaccatcc ttaggagctg ggatttcatt catgactttc atggcttcga taattaccaa
    26101 tgtttgacct tttttgacac tatcaccaac tgtaacgaag gcaggtttat ctggtccagc
    26161 agccaagtaa accactccaa caagtggact ctctacaaga tttccctcac tagccacact
    26221 tgcttcagct ggagctggaa cttcttctgc tacagtctct gctggagcag atgtaggagc
    26281 tactggactc ggtgttgcta gaacgggtgc tggagcgact tgagttgcaa cttcaggcac
    26341 aggtctcgct tcattcttgc taaactgcaa ctcatccgtc ccatttttat aagaaaattc
    26401 tctcaaactt gactggtcaa attgagtcat caagtcttta atatcgttta aattcatact
    26461 tatctattct cccaacgttt gaaagcaaga actgcattgt ggcctccaaa accaaaagta
    26521 tttgaaatag cgtatggaat ttctttctcc aagccttgtc cataaacgac attagcttcg
    26581 atataatctg atacttcact tgtcccagct gtcattggta caaagttatg acgcatagct
    26641 tcgatggtga cgatagcttc tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac
    26701 ttggttgatg atacaggtac ttccttacca agaacagcta cgatagcacc actttctcct
    26761 ttttcattgg caggagttga cgttccgtga gcattgacat aggctacttg ctctggagaa
    26821 atctcagctt cttccaaggc tagtttgatg gccttgatag ctccctgacc ttctggatgt
    26881 ggagaagtca tgtggtaggc atcacaagta tttccgtaac caaccacttc agccaggata
    26941 gtagctccac gtttttcagc gtgttcaaga ctttctagaa ccaacatccc tgaaccttca
    27001 cccataacaa acccattgcg atccttatca aatgggatcg aagcacgagt tggatcctct
    27061 gtagtagaga gagctgttaa ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct
    27121 tctgttcctc ccaccaacat cacatcttgg aaaccaaact taatggagcg gaaggcatcc
    27181 ccaatcgcat catttgatga agagcaggca gtattgatag atttacaaac accgtttgca
    27241 ccaaaacgca tggctacatt cccagaagcc atatttggta aagcttttgg aagagtcatt
    27301 ggtttgacac gtttgggtcc tttttcatga aggcgaagta cctgatcttc aatttccttg
    27361 attccaccaa taccagatgc aacgataaca ccaaaacgat ccctattaag agcctctaca
    27421 tcaagattgg catgatttac agcctcttgg gctgcataca aggcatataa agaatagtta
    27481 tcaaaacggt tggtatcttt ttttacaaag tatttatcga acggaaaatc ttggatttct
    27541 gccgcattat gcacatcaaa gtcactatga tcaaattttg taatgccacc aatgccgatt
    27601 ttcccagttg ctaaactatt ccaaaattct tctggtgtat ttccgattgg agatgttact
    27661 ccataacctg ttaccactac tcgatttagt ttcattcttt tcacctctag ctttcgctac
    27721 atacttaagc caccatcaat ggcaaccact tgaccagtta gataatcttg gcctgctaaa
    27781 aatactgtca aatctgcaac ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct
    27841 agtgtagctt ccttaatctt atctgataag atagctgtca tatcagactc aatcattcct
    27901 ggagcaatca cattgactcg tatattccga ctagcgacct cgcgtgccac agacttggta
    27961 aagccaatca agccagcctt agaagcagca tagttagctt gaccaatatt ccccatcaaa
    28021 ccaacaacac tagacatatt aatgatagca ccttctctgg ctttcatcat cggtttcaag
    28081 actgattgtg tcatattaaa ggcaccagtc agattgacct tgagcacttt ttcaaaatct
    28141 gcttctgtca tcttgagcat aagagtatct tgggtaatcc ctgcattgtt gaccaaaaca
    28201 tctactgaac ccagttctgc aatagcttga tcaatcatac gcttagcgtc tgcaaaatct
    28261 gatacatctc ctgaaatggg aaccaccttg ataccatagt ttgaaaactc agcgagcaat
    28321 tcttctgaga ttgccccacg actgtttaag acaatgttgg ctcctgcttg agcaaacttg
    28381 tgggcgatgg caagaccaat tccacgactc gaacctgtaa taaagatatt tttatgttct
    28441 agtttcattt ttttcctttc aaaacttcta cttattttag tctatttttc taaaagtgct
    28501 actaaactcg cttgatcttc cacatgagct aagtgagcag tttgatcaat ttttttaaca
    28561 aaacctgaca agactttccc cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc
    28621 atgaccccaa tactttcata gaaacgaacg ggttccttga cctgacgcgt caagagctga
    28681 gcaatgtcct ctttttgcat cacagcagct tctgtattgc cgactagggg acaagtaaaa
    28741 tctgaaaaac ttacctgagc tagagtttca gctagtttct ggctagcagg ctcaaggaga
    28801 gcggtgtgaa agggccctga caccttaaga ggaatcaagc gtttggcacc tgcttcttgc
    28861 aaaagttcaa ccgctcgatc aactgcaacc acttctccag caatgacgat ttgtgcaggt
    28921 gtgttatagt tggctggagt aaccactcca agttcagaag ctttttgaca ggcttcttca
    28981 atgacctcta ctggcgtatt gagaactgct accatcttgc cagagtcagc aggagccgct
    29041 tcttccatat aggctccacg cttagctacc aaggcaaccg catcttcaaa atccaaggcg
    29101 ccgcttgcca ccaaggcaga gtattctcca agagacaaac cagcaaccat atcaggctga
    29161 tagccctttt cttgcaataa acggtagata gcaaccgaag tcgctagaat ggctggttgc
    29221 gtatagcggg tctgattgag tttgtcttct tccgtatcga tgagataacg taaatcataa
    29281 ccgagcacct gactcgctcg atcaatcgtt tctttgacaa tcggatactg atcatagaaa
    29341 tcccgtccca tccctagata ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc
    29401 atttcttaca actcctgccc agcgagaggc ttcttcttga attttcttag cggctccgta
    29461 atacaaatct tttaggattt cttcagctgt ttcttcttta gaaacaagcc ctgcgatttg
    29521 acctgccatg acagagccac catccacatc accgtgaaca actgctttgg ctagggcacc
    29581 tgctcccatt tgttcaaaga tttctaaatc aggatcttcc tgcttaaagg catctttttc
    29641 agccagttca aaatctctag tcaactgatt tttaatagca cgaacagcat gaccaaagtg
    29701 ctgagctgaa atcgtagtat caatatccct tgcttttaaa attttctcct tgtagtttgg
    29761 atgggcattc gactcttttg caactacaaa ccgtgtcccc acctgtacag cctctgcacc
    29821 tagcataaag ccagccgcag caccttcacc atccgcaatt cctcctgcag caataacagg
    29881 aatagatata gctgtggcta cctgtcgcac caaggtcatg gttgttaatt taccgatatg
    29941 ccccccagct tccattcctt ctgcaataac agcgtctgca ccgatttttt ccatgcgttt
    30001 agctaaagcg acactaggaa caacaggaat aacgattatc ccagcttcat ggaaacgttc
    30061 catatacttg cttggatttc ctgctcctgt tgtgacaact ttaacacctt cttcaataac
    30121 gagatccacg atatcttcca caaagggaga taagagcatg atgttgaccc caaagggttt
    30181 atcagtcaat gatttgattt tatcaatatt ggccttgaca acttctttcg gggcatttcc
    30241 cccaccgata attcctaatc ctccagcctt ggaaacagcc cctgccaaat caccatcagc
    30301 aacccaggcc atccctcctt ggaaaatagg atagtcaatc ttcaataatt ctgtaatacg
    30361 cgttttcata gtgcctccaa ccttccttgc ttacgtaata gttcgatttc accataattt
    30421 gacagtcaaa ctattaccta aacaagaggg agtgggtttc tccctactcc ttctactaat
    30481 attctgctta ttttgcttgc tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt
    30541 cattttctgc ttcgatttgg atatcaaaag catcttcgat ttctgagatt acttggaaca
    30601 agtccaatga atctgcgtcc aaatcatcaa aagttgattc aagtgttact tctgatgcgt
    30661 cttttccaag ttcttcaacg ataatttctt gtactttttc aaatactgcc atgataggac
    30721 tcctttaaaa taaatagttt ttttataaca atgtgttcac cacatgatta cctaaattgt
    30781 aagaatgagc gtgccccagg tcaagcctcc accgaagcct gatagaagaa cagtctggct
    30841 accatctaaa gggatgagac cttgttctac acactctgaa agtaaaatcg ggatactggc
    30901 tgcactggta ttgccatatt ccatcatatt ggctggaagt ttggctcggt caacaccaat
    30961 ttttctagcc atcttatcca aaatacggtc attggcttga tgaagtagca gataatccaa
    31021 gtctgtcacc tctataggag attcatcaat agtctgcttg atagacttgg ctacatctcg
    31081 aatggcaaaa tcaaagactg tgcgtccatc catcttcaaa aacgaatctg cactttcttg
    31141 atctgaaaat ggagaatgca aacctgaatg cccataagtt aaacactcgc tgcgacttcc
    31201 atcgctattg agactctcag ctaagaaatg ctcttgctcg ctagcttcta acaagacacc
    31261 accagcacca tctccaaaca acacagctgt tgatcgatcc gaccaatcga ctgccttaga
    31321 gagggtttca ctaccaatca ccaagccttt ttgaaagcga ccagaagcga taaacttttc
    31381 agcagttgaa agagcaaata caaatccact gcaagccgcg gttaagtcaa aagcaaaggc
    31441 tttattagcg ccaatattag cttgaacacg agcagctgta gagggcatca tcgaatctgg
    31501 agtaatggta gctaggatga taaaatccag ttcttttcct gttattccag cttttgccat
    31561 cagtttctta gcaacctctg tagccaaatc actggtagat tctgttcttg aaatatgcct
    31621 ttgtcgtatt cccgttcgac ttgaaatcca ctcatcattg gtatccataa tctgagccaa
    31681 gtcgtgattt gtaaccactt gctctggcac ataatgagca acctgactta tttttgcaaa
    31741 agccattatt tcaaatcctc caaaaattgg taaagattag tcaagccttt acccatgaca
    31801 gcaatttctt cctcgctcat gccatcaata attttttcta ccatggcctt gtggaagcgt
    31861 ttatgcagtc tatgaatcaa gcgacccttc tttgtcaaat gcagatgcac cacacgacga
    31921 tcctgttctg accgaactcg ctcaatgtag cccttacgct ctaaattgtt caaacttgtc
    31981 gtaacagttc caagagttac catcaactct tttgacactt gacttggagt cacatctgga
    32041 gccttaccga tgacattaat cgtatgcatt tctttgatgg agatatcctt aaaacgacta
    32101 cctctcaagt tcacttcctc aattacaagg acattgttaa atatagatgt taaatattca
    32161 ttgattcgtt ggtagtccat ttttcatatc cctccttctt caaaaaactt ttacaatcaa
    32221 aacatttgac agaaagaatt atatcaaaat tcaaagaatg atgcaagtat tttttatttt
    32281 cctgtaaatt taggtcttct tctctccgaa tgagctcgca ctccttcttt gaaatcctct
    32341 gtttgagcta aggatttctg taggttcagt tctaaagtag cgtaaccctg ccagtcttta
    32401 aactggctct cccaaaccaa cttcttaatg gcagcatagg aattacttga agcacgtctt
    32461 aattttttaa gaagctgttc tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa
    32521 accaaccccc attctagggc tttttctgcc gttaaagcct ctcctgtcat agctaattga
    32581 gcagcacgcg tcacaccgat actgcggctc aagagatgaa ttccccctgc atctggagcc
    32641 aaaccaacac caacaaaggc ttggataaac ttagccttat ccgtcgccaa acagaaatct
    32701 gccgcaacag ccatattcgc tgcggcacct gcaacagcac cgtcaacttc cattaaaaca
    32761 ggtttggcta tttgcttgat tttataagaa atcgtattga ccaactctgc gatttttgtc
    32821 aatgatggaa tatcatcctc atccactgcc cgcttcatct ctaccaaatc tcccccaact
    32881 gagaagacct ttccattggc attgattaag ataaaatgca cagctggatt ttcttctgcc
    32941 aaagtcagag cttctaaaat ctcctcacac atgggaatat gaaaaccatt tgcgacctca
    33001 ggacggttca aggtaaggat tgccaagtcc tcttcaagct gataaataat gtgttccatc
    33061 agggctcctt tttattttat aagcagttta tactcttcga aaatctcttt aaaccgcgtc
    33121 agcttccatc tgcaacctca aaacagtatt ttgagctgac ttcggctagc ttcctagttt
    33181 gctctttgat tttcattgag tgttaaatta tttcactgtc aaagtatatc ttttttagga
    33241 gcagaaagca agaaaaaatc gactgaaagt gtctcagccg ataagaaagg ctcgctttag
    33301 gctagaaagc atcttatttt cttcattgaa aaaagccttt ctttctgcta taatcgtata
    33361 aaatacttac tttaggagtt cttatgaaag ttgttaaatt tggaggtagt tctcttgcct
    33421 ctgctagtca attagaaaaa gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg
    33481 tagtcgtttc tgcgcctggt aaacgcaatg ctgaagatac taaggttacg gatgccctga
    33541 ttaaatacta ccgcgactat gttgcgggta acgatattag caagagccaa agctggatta
    33601 tcgaccgcta tgctgctatg gttagtgaat tgggactaaa accagctgtg ctagaaaaaa
    33661 tttctaaaag cattcacgcc ttggccactc ttcctattga agaaaatgaa tttctctacg
    33721 atactttcct agcagccggt gaaaataaca atgccaaatt gattgctgcc tactttaacc
    33781 aaaatggtat cgatgcacgc tatatgcacc ctagagaagc tgggattgtg gtcacaagtg
    33841 aacctggtca cgctcgcatc attccatcaa gttatgacaa gattgaagaa ttgacaaaca
    33901 ccaatgaagt ccttgtcatt cctggtttct ttggtgtcac taaggaaaat caaatctgta
    33961 ctttctcacg tggaggttct gatattacag gttctatcat tgctgctggt gtcaaagctg
    34021 acctctatga aaactttacg gacgttgatg gtatctttgc agcccaccct ggtattatcc
    34081 accaaccaca ctcgattcct gagttgacct accgtgaaat gcgcgagttg gcctatgcag
    34141 gcttctcagt ccttcatgac gaggctcttc ttcctgccta ccgtggaaaa attcctctgg
    34201 ttatcaagaa taccaacaac cctgaccatc caggtactcg tatcgttcta aaacacagta
    34261 atgatgaatt tccagttgtg ggaattgctg gtgactcagg ctttgtcagc attaacatgt
    34321 cgaaatacct catgaaccgt gaggttggat ttggccgcaa ggttctgcaa atcctggaag
    34381 aacttaacat cggttgggaa catatgccaa caggtatcga cgatctttct atcattctcc
    34441 gttctcgcca actaactccc atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg
    34501 ctaaagtaga tcatgcagaa atcgaacacg acctttctat cattatgatt gttggtgaaa
    34561 aaatgaagag ccacatcgga gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa
    34621 tcaacatcca gatgatgtct caaggttcta gtgaagtttc tattatgttt gttgtcaata
    34681 aagaccaaga gaaagcagca attaaagccc tctacaatgc cttttttgga gaaagtaagg
    34741 aagactaagc atggcccaat cacttaacaa aacagtactc ctcagtacga caggcacttc
    34801 ctacctctct atcgctggga aagttgggaa attccttgtc ggagatcagg ctttggaatt
    34861 ttacccagat gtcaatgtcg aacaatttat ccagattcct tggagccata tcaatcagat
    34921 tggagccaat gtcactggat gcaaaatcag ccgccacttc gaagtcttta cagacaaagg
    34981 aaaattcctc tttgcttcaa aagactcagg tgccattctc aaaattgcac gcgaaaaact
    35041 aggcaatgac aaggtcgtca aacttccgac cctgattcag acaattagcc aaaaatttaa
    35101 aaatctattt gcaaaaaagt agaaacttta gtataatcat agcaacggat aagtaggtta
    35161 tcttcttctt tcagaaagtc tgcgggtact gcgagcagat aggagggata ggtgaaattc
    35221 taccgttagt aacaattaca tacacaatca agtgcacacc tgtgaagttg gatggaaccg
    35281 tggccctgcc actccaacgt tttgtcaggc gtgctttttt cataaaggag ttcttatgtt
    35341 agatatcaaa cgtattcgta cagattttga agctgtcgca gaaaaattag ctacacgtgg
    35401 tgtagatgct gctgtcttga atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt
    35461 ggtcaaggtt gaaactctca aagcagaacg taacacagtt tctgctgaga ttgcccaagc
    35521 taagcgcaac aaggaaaata cagatgacaa gattgctgcc atgcaaaatc tatctgctga
    35581 ggttaaagcc ttggatgctg aattggcaga aatcgatgct aaattgacag aatttacaac
    35641 gactcttcca aatatcccag ctgacagcgt tcctgttggg gctgacgaag acgacaatgt
    35701 ggaagttcgc cgttggggta ctccacgcga gtttgacttc gaacctaaag ctcactggga
    35761 tctcggtgaa gaccttggta tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg
    35821 cttcctcttc tataaaggcc tcggtgctcg tttggaacgt gctatctaca actttatgtt
    35881 ggatgaacat ggaaaagaag gctatactga agtcatcaca ccttacatag tcaaccatga
    35941 ttctatgttt ggtactggtc agtatccaaa atttaaggaa gatacttttg aactcagcga
    36001 taccaacttt gtcttgattc caactgctga agttcctctg acaaactact accgtgatga
    36061 aatcttagac ggcaaagatc ttccaatcta cttcactgct atgagtccgt cattccgttc
    36121 tgaggctggt tctgccggtc gtgatacgcg tggcttgatc cgtttgcacc aattccacaa
    36181 ggttgaaatg gtcaaatttg ccaaaccaga agaatcttac gaagaattgg aaaaaatgac
    36241 agccaacgct gaaaacattc ttcaaaaact caaccttcca taccgtgtcg ttgctctctc
    36301 tactggagat atgggcttct cagctgcgaa gacttacgac ttggaagtgt ggattccagc
    36361 acaaaacaat taccgtgaaa tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg
    36421 tgcccaaatc cgttaccgtg atgaagcaga tggcaaggtg aaactccttc ataccttgaa
    36481 cggttctgga cttgcagttg gacgtacagt ggctgcaatt cttgaaaatt accaaaatga
    36541 agatggttct gtgaccatcc cagaagcact tcgtccatac atgggtggag ctgaagtcat
    36601 caaaccataa aaaataaggt ttagctattt ctagctagac cttttttcgt aaccaaatca
    36661 gataagcacc tagtacaaag aataaaatag ttaggcatat aatggtttca gccaatacca
    36721 ggtaatccag aaatggaagt ttcaaaattc cctgagccat cttgagcgag gtcgctgtga
    36781 taatggttgg gaaggtgagg gctgagaagg ctggttgaaa accttgtttt aaaatgttgg
    36841 gcagacgagt taaaacaaag aaaaagaagg attgagaagc caaaatcatg acaatcaaga
    36901 cccaagtcgg caggctggtt cctcctactc gaactagaga agccaagagt agagagaaag
    36961 gagcacagta gattccttct tgtccaagca aggctagtgg gagtggatgt ttctttaaat
    37021 cgctataaat aaggggatag agatagaagg tcaagagaaa accaaaactc aaggtcgcat
    37081 aggcaatttc gataatacct accagaggat aggtcaaggc agccactgct atccccacat
    37141 agagaaccgt ccagcttgga gtggcatgaa ccctccgccc tggacaagca aacttgatgg
    37201 taaaaccagc aatcaaggtc aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta
    37261 ccaaaggaag ataagagaat acgcgaaaga cataggtcga taaaatcatc ccagccatag
    37321 gaaaggttgc cattcctgac aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc
    37381 aattaaagag atgcagaatt agaaagtaaa tccataaaac caaaccagtc agactaaaaa
    37441 gatgggatag aaccggcaac gtatctaaaa taagatttcc agctcctgcc aaacctagca
    37501 aacaacctga aaatactaag gggagttttt tcatcctaac ctccaataat catgttagtt
    37561 tcagtataac ataaaagcgc ttaaatgagg atttaaaaaa acgaagtccg cttatttcag
    37621 acttcatttt actcagatat gaattaggca taaggttgca attctggatt aattggtgta
    37681 ttagctaagt tgttggcata gttacagagg attgctaggc tgacaccaaa aaccacatcc
    37741 aaggcatttt gttgagtgta gccagcttct aaaaactcag acaaggcttc atctcctaca
    37801 cgacccttgg tattgataac tgccaaggta aacttagcta gggtatccaa tttaggatct
    37861 gtttcaattg gagtacgatt gcgaagagct tgaatcaagt catcattcat ctggatttgt
    37921 ttgatggaaa aggctgtgtg acctgcgaca cagaaggcac aaccattggt cacggctgcc
    37981 gtgatttgca ccacttcacg ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag
    38041 acaatttggt aggcttctaa aacagtcggg gcattggcca agagaccgat taggttggga
    38101 atatagccat tgttgtcttt ttctactgtt tcaagaattt ctttcacttc tgctggtgct
    38161 gactctactg tatggatagt aaatgttgtc ataagatacc tcttttctta ttattgacac
    38221 taatattatt ggaaaatctt ataaaatcct gattcctaag tttatctaag ataaagcttt
    38281 attctctcat aagattttcg ttgttatatt agtttatcac acttccaatc acttgcataa
    38341 tatatattat atatcaggct gataaaaatt atttataggc aaaaaaatca cacgagctgt
    38401 gtgattccat tatttgtcaa aatacttttt agtttcagca ataacgactg gcgacaagac
    38461 caagagggca atcaagtttg gcagagccat caaggcgtta acgatatctg cgataatcca
    38521 gaccatatcc aactcgataa atcctcctaa caagaccatg agcacaaaaa ccacacggta
    38581 gagccagata aagcgaaccc caaagaggaa ctcaaaacag cgttctccgt aatagttcca
    38641 acctagaatc gttgtaaagg caaaaagtac aaggaagatg gtcaagaggg caggcccaaa
    38701 gtgtgaaaag actgttgaga aagctgactg agtcaaggca accccattca agtcaccact
    38761 ccaaactcca gttaccaaga tggtcaaacc agttagagta caaatgatga gggtatcaat
    38821 aaaggttcct gtcatggaaa tcaaaccttg ctctactggt tcatttgtct tggcagctgc
    38881 agctgcaata ggagcagaac ccagaccaga ttcgtttgag aacacaccac gcgccacacc
    38941 attttgaata gccatccgaa cgctagcacc agcaaatcca cctaccgcag caaggggact
    39001 aaaagctgag gtaaagacta aagcgattgt gccagggatt tttccaatat taaagaaaat
    39061 aactgtaaga gttcctaaga tataaatgat ggccataaaa ggaacaacag tagttgaaac
    39121 cttagaaata gacttgagtc caccaaagac tgcaatcgct acaaagacag acaagacgag
    39181 agctgtgatg gctggcgaaa tcgtcgttgt attttggata gattctgcaa tcgagttgac
    39241 ttgggtgaag gttccgattc ccaagagagc aaccaatact cctgctactg caaacaaaac
    39301 agcaagtggt cgccactttt ctcccatccc tagaaggata taatgcatgg gacctcccgc
    39361 tactgcacca tggtcgtcct tggtgcggta tttgatggcc aagagtcctt ccgcatactt
    39421 ggtagccatt ccaaagaaag ccgccatcca catccaaaat agagctcctg gtccaccaac
    39481 cttgatagcc gtcgcaactc ctatgatatt tcctgttcca acagttgatg ccaaggctgt
    39541 acacagagct gcaaaactgg atacatcacc atgtccctta tcctggataa aaataagctg
    39601 aaaagccttg ggcagacgca aaacctgcaa gagtcctagc cgaatagtta ggtaaatccc
    39661 tgttccgacc aataaaatca agaggggcgg tccccaagca aaagcatcga ttgatttaag
    39721 caattctaac atttccttct cctatcgttt caaccccaaa agaaagagca catgcaagat
    39781 acatgtactc tggaatgctt agataaatgc taaaaagcgg tctatcctag ctctgtcctt
    39841 ttacctgaga gtttgagcag ttgcctgcct tgccccttcg gtgcctttac ggtctctcca
    39901 gagttccgtc catttacagt catggaaaat caaacgattc cccacttcta ttaaacttca
    39961 ttcggtgttg gtatttaatt gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg
    40021 tttattagta aaaattagtt caacagtttt tactttataa agtccagaat actgctatcc
    40081 tttaaaagtg acaatagtcg caccactgcc tccagcattt tgtggggcat agccgaaact
    40141 cttgacatgt ttgtttcttt gcaagtattt ggtaactcct tcacggatga ctcctgttcc
    40201 gataccatgg atgatatcaa cttgagccat attgttaagc aaggcttggt cgatgaaggt
    40261 atctagctca ttcatggctt cttcatagcg cttgcctcga agatccagtc tagcttgagg
    40321 tcctcgccca gaagttcgtt tcacaacatt gacctgtttc ttcttgactg gtttttcttg
    40381 ctgggcttga acaagatcaa actctttctc ttccaaggtc atcttaatca agccaacttg
    40441 ggcttcccag cggccgtcct tgagttgact ggtcaaggta ccacgctgac cataactgag
    40501 aaccacgata tcatctccca cctttggagc tcgttttttc ttggcctttt gaaggacctt
    40561 gtttttagac aagtccactt tttcaggagc caattttttc aacttggcct tggcttcaat
    40621 gatttcgtgg ggcttgagtt gggatttact gtggagattt ttgagaatct ggtcactttc
    40681 acttagggcc atatccacaa tctcagcagc ctgttcacgc gccttgttaa gctcggtttc
    40741 cttttcacga ttaagctcgt tgtagagttt ttttagcgca cggttcatct tgagattttc
    40801 ttgctccacc tcacggatat tgtccaagcg tttgcggctt tccagcgtct gctcttctaa
    40861 ttgctcaatg atacgattga cgtcattgtc ctgatcgatc tgctgactgg catctcctac
    40921 gataacttca gataggccta gacgtttggc aatttcaaag gcattacttc ggccaggaac
    40981 accctgcata aagcgatagg tcgggcgaag agttgcagta tcaaactcca tactggcatt
    41041 ttgcacaaag gctgtctcaa taccgtaggc cttgagttct ggatagtggg tcgtcgccat
    41101 ggtcttgatt tgacgcaggc gaaggtcctc cagaatagcc atggcaaggg ctgctccctc
    41161 ttggggatca gtaccagccc ccaactcatc caaaagtaag agtgaatgtt ggttgacctt
    41221 gccaagaata tccacgatat tggtcatatg gctagagaag gtagacaagc tctgctcaat
    41281 agactgctca tctccaatat cagcaaagat ttcttcaaaa ataccaacac gacttccctt
    41341 gtctgctaaa atcggcaatc ctgactgggc catgacctgt gtcaagccca gagttttgag
    41401 catgatggtc ttcccacctg tattgggacc tgtaatgaca atagctgtta aatcttgacc
    41461 aaaatagaca tcatttgcga cggcattttt gaccaaagga tggcagacat ggagcagttg
    41521 aatctcttga ttttctgaca gctgaggcac gactgcttgt ctttcttgga taaatcgaac
    41581 cttggcacga atcaagtcca aatgaccgat aatccaagcg tcattagcaa tctcagccgc
    41641 atgagggcgg acacgctcag aaatttcttg gagaatgcga agcatttcat agcgctcatc
    41701 tgctcgcaga ctagcaattt cttcgctcag tttgactacc tcacgtggtt cgatatagac
    41761 ggtgtttcca ctagcagaaa tatcatgaac gacacctgca atcttattgc ggtaggtgtt
    41821 tttgactggt aaaacctgac ggccatttct gctagcaaca attccttccg tcaacatctg
    41881 cgctttttgc ttgagcaagt cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat
    41941 ttttcgacgg attcgcgcca attcttcact ggcaaaattt tcaatgaaac ccgcatcatt
    42001 aaaggcctga agatttcctt gtaattgcgg aaaatcatgt aatttctcaa accaaagggc
    42061 taattcttcc aagctgacat tttccagatt ggcgtaaaaa ctttgaagtt ctcggctggc
    42121 aagaagcacg cgtttcaaga gtaggaactc ctcgatattg agatccgctc ccatctccaa
    42181 cctcttgcag actcctgcaa tttccttagt tgagagaata gtaaaatgcg gttgctcgac
    42241 gaaaagagcc tgcatttctt tcatctcagc aaaagcctgt ttgattttat ctgctttggc
    42301 agtcggagcc agctgtctca attgctccaa gccctgctcg gtcaacaaat gaggctcaaa
    42361 caaggccttg accttatcga actctaatgt ttctaatatt ttcttattca tctttatttc
    42421 cttgtctttg aatgtctagg tgtggtagct ttttacattc tgatagattc gagtcaaatc
    42481 tgtaaacaaa gggctaggaa aactcctgcc ctttttatcc gattaaattt gtcacccaga
    42541 tttgtttgag ccaactggtt gttatcggta tgctctggat gatgtgtttt gcgacgatac
    42601 tcttttcaag aggattttgt ataactgcca tggggatggt cgccaagatt gtcaaggcca
    42661 tttgcaagac aaataaggtc accaacatag acaagatacc tgctgaaact tggaacaact
    42721 taccacccag ttttttgcta ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc
    42781 tatagacaat cccaaataca agcaagtagc cgatacctgc ataaaagacc ttatccagct
    42841 gaaagagttg atccgatggg aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag
    42901 ggagcaataa atggaattgc tctccaagcc ccttataaaa ctggccagcc ataaaagccg
    42961 atgccatggc tgaaatcagg taataaacct gtaagagcag gcctctccga tagccgatat
    43021 aaaatcccca aaccaagacc aatagaagaa ggaatgaaat cataaggaat cctcaatctt
    43081 gctctgttct tgcttacaag tcacaagctt gtgacggagt tcttctagct cttgctcctt
    43141 atcgtcaaat tcaatctcac ggctgagctg agttgataaa cagttgactg ccaacaaaag
    43201 agcgattgtt tcatcatctg cgctaggcat ttgttcttta attgcttggt atttttctgt
    43261 cgcaacctta gcgatttcct ccataaaaag gttatcatgt tcgcttgtca aggttaacga
    43321 ttttttcccg aatgtaaatt tgaatcgatt tagatttgcc ataaaattca cctcacgata
    43381 ttataccaaa attcgctaat tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa
    43441 tagaaactat ggcaagtatc acactcacac caagcgaaaa ggatattcag gcttttcttg
    43501 aacactatca aaccagtctg gctcctagca agaatcccta tatccgctac tttttgaaac
    43561 tacctcaagc aacggtttct atctatactt ctggaaaaat cttgcttcag ggtgaagggg
    43621 ctgaaaaata cgccagtttc tttggctatc aagctgtaga gcaaaccagc ggacaaaatc
    43681 ttcctttaat tgggacagat gaggtgggaa atggttccta ctttggtggg cttgcagttg
    43741 tggctgcctt tgtcacatct gaccagcacg actttttacg aaaactcggt gtgggggatt
    43801 ctaagactct gaccgaccaa aagatccgtc agattgctcc tattctcaag gaaaaaatcc
    43861 agcaccaggc actccttctc tcacccagca agtacaacga ggtcatcgga gaccgctaca
    43921 atgctgtttc ggttaaggtt gccctccata atcaggctat ctatctcctc cttcaaaaag
    43981 gtgttcagcc tgagaaaatt gtgattgatg cctttaccag tgctaaaaat tatgacaagt
    44041 acttggcaca agagaccaat cgtttcagca atcctatcag cttagaagaa aaggctgagg
    44101 gcaaatactt ggctgtcgca gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc
    44161 ttgaaaattt gggacgagaa ctgggttatc agcttccaag tggagctgga acggcctctg
    44221 acaaggtggc tagccagatt ttgcaagcct atggtatgca gggactcaac ttctgcgcta
    44281 agctacactt taaaaatact gaaaaagcga aaaacgctta gaaaggtaag ttatgaattt
    44341 atttaaaaat ttcttaaaag agtggggatt attcctcctg attctgtcat tactagcttt
    44401 gagccgtatc tttttttgga gcaatgttcg cgtagaagga cattccatgg atccgaccct
    44461 agcggatggt gaaatcctct ttgttgttaa gcacctccct attgaccgtt ttgatatcgt
    44521 ggtggcccat gaggaagatg gcaataagga cattgtcaaa cgtgtcatcg gaatgcctgg
    44581 cgataccatc cgttacgaaa atgataaact ttacatcaat gacaaagaaa cggacgagcc
    44641 ttatctagca gactatatca aacgcttcaa ggatgacaaa ctccaaagca cttactcagg
    44701 caagggcttt gaaggaaata aaggaacttt ctttagaagt atcgctcaaa aagcccatgc
    44761 cttcacagtt gatgtcaact acaacaccaa ctttagcttt actgttccag aaggagaata
    44821 ccttctcctc ggagatgacc gcttggtttc gagcgacagc cgccacgtag gtaccttcaa
    44881 agcaaaagat atcacagggg aagctaaatt ccgcttctgg ccaatcaccc gtatcggaac
    44941 attttaagag acctaagagg ccgagaatca caaatctcag cctcttcttc tatcgtgaga
    45001 agtgattgtt tattgacaaa tactcaatga aaatcaaaga acaaactagg aagctagccg
    45061 taggctgctt aaaacagtgt tttgaggttg tggatagaac tgacgaagtc agctcaaaat
    45121 actgttttga ggttgcagat ggaagctgac gtggtttgaa gatattttcg aagagtataa
    45181 aataaaaaca atcccaactc tcacctattc atgcaaagga attttatgga agtttatttt
    45241 tcaggaacca ttgaacggat tatttttgaa aatcccagca atttttatcg catcctcctc
    45301 ctagaaatcg acgatacgga cgcagaggat tttgatgatt ttgaaatcat tgtcacagga
    45361 accatggctg atgtaattga gggcgaagac tatatttttt gggggcaaat tgtccagcac
    45421 tccaagtatg gagaacaact gcaaatcagt cgttatgatc gcgcaaaacc aactagtaag
    45481 ggattggtca agtacttttc aagtagccat ttcaagggga ttggtctcaa gacagctcag
    45541 aaaatcgtag atacctatgg cgaaaatacc attgatgaaa ttttgcaaca cccagaaaag
    45601 ttagaaggca tcgcaggact ctctgccaaa aatcgcgagg ctttcgtctc cactctccgt
    45661 ctcaactacg gaacggagat ggttttggcc aaactagcca actacggcat tcccaacaaa
    45721 ctagcctttc agattcaaga cttttacaag gaagaaaccc ttgatgtggt tgaaaattat
    45781 ccctaccagc tggttgagga tatcaagggt ttgggcttta caattgctga ccaactagct
    45841 gaggaactag gcatcgaaag tcaggctcct gaacgcttcc gcgccggtct agttcacagt
    45901 ctttttcagg cctgtatgga aacaggggac acctatgttg aagcacggga tttgctggaa
    45961 caaaccctta ctctccttga gtcttcccgt cccgtggaac tagaccccag ccaagttgcc
    46021 caagagctct cctacctgat cgaagaagac aaggttcagc agattgatac caagatcttt
    46081 gacaacagcc tctttttcgc tgaggaaggc atccgcagtc acttggttcg tatccttgaa
    46141 aaaggaaaac agaagagtca tgatttagaa accattcaaa aacatatcac tactatcgag
    46201 gaagagctgg gaattgagta tgataacatt caaaaacagg ctatctgtga cgctatccag
    46261 aacaaggtct ttatcctgac aggtgggcct ggtactggta agacaactgt tatcaatgga
    46321 atcatcgctg tttatgccct tttagaagga cttgacttca ggaagaaaaa caatctgccc
    46381 attcttcttg ctgctccaac tggacgagcc gctcgccgca tgaatgaatt gacaggtttg
    46441 cctagcgcga ccatacaccg ccacttggga atgacaggtg acgatgatac cagtcatctg
    46501 gaagattacc tagatgctga ctttatcatc gtggatgaat tctctatggt ggatacttgg
    46561 ctggccaatc aactcttctc caatatctct tctaacagta agatcctcat cgtgggtgac
    46621 agtgatcagc taccttctgt cagtcctgga caggttctag cggatctgct tcatattcct
    46681 ttgattcctc agactcgctt ggaaaaaatt tatcgacaaa gcgaagaatc aaccatcgtc
    46741 accctagcta gtcagattcg acagggcatc ttgccagctg atttcaccca aaaaaaagct
    46801 gaccgttcct actttgaaat tgctagtggc catattcctg ccactattga aaaaatctta
    46861 gatgccgccc tcagaaatgg tattcctgcc cgtgatatcc aagttctggc tcctatgtac
    46921 cgagggacgg cagggattga tgctatcaat cagctcatgc aagacctgct caatccccca
    46981 caaaaagatc aactcagttt tgaagctcct cagtgccact atcgtaaggg agacaaggtc
    47041 attcatttgg ttaacgatgc tgaaatcaat gtctttaatg gggatttagg agctatcaca
    47101 gacctgattc ctggtaaata caccgaatcg aaacaagacg agattgtcat tgattttgat
    47161 ggtaatgaag tctcttaccc ccgtaacgaa tggtacaaga ttcgcttggc ctatgccatg
    47221 agtattcata agtctcaggg aagtgagttc ccagttgtca tcctaccgat tactagtgct
    47281 agccgacgta tgctggagcg aaatctcatc tacacagcca ttacacgtgc caaaagcaaa
    47341 ctcatcttac taggcgaatt acaagccttc gactatgcta cccaacacat cggaactgcc
    47401 cgaaaaacct atctgattga acgcttcagt gatctactgg agaatgttga agaaaagcaa
    47461 caagctgtct ctgaaacagt cacatcaagt gcctctgaac aatcctacat cctaaccgaa
    47521 gaaaactggg acagcattcc agccatgatt gggattacag acacagacct caaagagatt
    47581 tttggaaaat agtacatcag aaaacccacc aattcaggtg ggttttctgt ttattaagat
    47641 tattttactg ttgctgtgct tgtgatcaat tcaacagctt ttttgatagt gatatcatgt
    47701 ttcaacatgt cagctgaaag caagttttga acttgtgcaa cttccatgtt gtagtctgct
    47761 gccaattgct caacttcttt ttggatttct tcttctgaag catcaaatcc ttcagctttg
    47821 gcaactgctt cgataacaag gttagtctta gtacgtgact cagcttctgc ttggtattgg
    47881 ttgtgaaggt cttcttgagt agttccagtg atttggaagt acatgtcagg gttgatccct
    47941 tgacgttgca agttcccaag gaattcattt actgaacggt gaacttcttc gtggatcatt
    48001 tcttctggaa gttctacgat ttcagcattt tctacagctg tatcaattgc tgcaccttca
    48061 actgcatctt tgtaagcttc ttctttagca gtagccaatt ctttgcggta tttttctttc
    48121 aagtcagcaa gtgtttcaac ttcttcatca atgtcttttg caagttcatc gtcaagagct
    48181 ggaacttctt tagcttttac ttcgtggata gttgtcacga atttagcttc tttacctgca
    48241 aggtcttctg cttggtagtc ttctgggaat gttacgataa catcaacggt ttcgccagct
    48301 gagtgaccta ccaattggtc ttcgaaacca gggatgaatt gacctgaacc aagtccaagt
    48361 gagaagtttt caccttttcc accgtcaaat tcaacaccgt cgatagaacc aacgaagtcg
    48421 atcacaacag tgtcgccgtt ttcagcagca gcttccttga taaccaattc agccaggttg
    48481 ttgcgttcgc gttcgatacg ctcttcaaca tcagcgtcag ttacttcttt ttctacatca
    48541 actgatactt caaggttttt gtagtcaccc aattttactt caggttttgt aacgacttca
    48601 gcagcgataa cccagtcttg acctttttcc attgaagtta cgtcaatttt tggttgggca
    48661 accacttcaa gaccagcttc ttttacagct gcttcataag cgtttggcaa aagagcgttc
    48721 attgcatctt gataaagagc ttcttcacca aatttttggt cgaagatagg gcgtggaagg
    48781 tgacctttac ggaaacctgg aacattaaga gatttcttca ctgacttgaa gacacggtcc
    48841 aattctggtt tgatttggtc ttgagagata gtgaaagtca agacaccacg gtttgtttct
    48901 ttgttttcaa atgatacaga cattctgtca tttctcctta aaatttttta aatacagtct
    48961 attataacat tttctataaa taaaatctag actaatgcag ccaattatag acaacaagcc
    49021 tttttcctaa ctaaaacact cataaagtat agacaatttt agactacttt ggatatcttt
    49081 tggttagtca ttttccaaaa ctaatttatc taatttttca gttatatagt agattgaaac
    49141 tagaatagta cacctctact tctaaaacat ttttagaaat cgatttgact gtcccgatcg
    49201 atttgtcctg ttcttgtttc attttactat atagatcgca ttcgaaagaa ttcgttccaa
    49261 aattgcttgg ttcgttcttc tcttggacga ctaaagaatt gatgggcatt atttttttca
    49321 acaattttcc cactgtccat aaaaataaca tgatgggcta catctctagc aaaacctatc
    49381 tcataaagct gatcaaaaac tcaatctgag gagaaaatcc aataaggctt tccataataa
    49441 aggacatcct atcaagattt ttgaacaccc gataggctgc ctttttccga ttttgaagac
    49501 tttttgtcca gcttctttta ccttataaat aacaacaaaa atcaaagaca agctagaaag
    49561 attaccgcag ataactcaaa cagtgttttg aggttgcaga taagactgac ggagtcagct
    49621 caaagcactg ctttgaggtt gtagatagaa ctgacgaagt cagtaacata tgcctaagac
    49681 aaagcgatgc taacctgatt tgaagagatt ttcgaaaaag attaaatata ctctacaatt
    49741 tgctcaatca attcttggtc gtctaaacct gtaacttgta taacaacatc tttgactgat
    49801 tgtttagcca acaattcacc taatcgaata ctttcttcat catttacatc gcgatagtca
    49861 aaggcatagc caactgtttt aagtaggttt ttatatgaca aactgagttc tttcaattca
    49921 cgtatcggcc ggatgaatcg ttcattatag cctaattttc ggattggagt gcgagctacg
    49981 cgactaacct cgtccgctat gaaagggttt ttaaaccgtt ctataatgac tttgtgataa
    50041 ttctccaatt cttttttatc aaagttccat ttggcaatca agagactccg aatttcagct
    50101 aatacagatt caatccgaga tttgatatta ggattttgaa gagcttccaa aattgtcttg
    50161 gcaccataat gcgcaccaat gtaagctgaa gttgcatgtc cagaattgac tgaaaaaagt
    50221 tttcgctcaa taaagggttc taaatcttct tcataatgca catcttttag acgtaaatct
    50281 ggatttttaa gacgcttggt ttccacgacc cattcattaa agggctcgac cacaacaaaa
    50341 agggaatctt cgtgactttg tgctggaaca atcctgtcta ctgcagcatt tggaaaacct
    50401 atgtagttat cagcaaatgt caaaccttcc ggacttaaat atttcttgac ttcttgataa
    50461 agaaattgag acccgccaat catattttca caggccataa catccaatgc ctgtgtattt
    50521 cctgcaactc ggcgagcttc gattcctttg gctagaagtt cggcgataaa agggagtata
    50581 ttaggtccga ttgcagtagt aataatatcc gtcttttgaa tcgcttcaat gacttgctca
    50641 ggatgttctt tgctattaat gccagccaca ttagttactt ctatacgaga ctgtcctttc
    50701 tgtgcaattt caatttcata cttgcccttt tcatttagag catgaattat ctgattattg
    50761 acatccacaa aatcaatatg gaaaccattt ttaaatagaa tttcacctat aaaaccacga
    50821 ccgatattac cggcaccaaa atgaacagaa tgtttcattc aatttctcct tttcctattt
    50881 gagggacata tatactagat gacaaatgac gaaattcaat tattcaacag catcaaataa
    50941 gcgcaatact tcctcttttg actgagcacc tgctagttta agaacattat ctacatctgc
    51001 acagaagata gaaattttct gaataatttc taagtgttca ttaccaatac cagcaatacc
    51061 aaaaagaacc gttgccactt gagggttaga tacattccca aaatcaaccc ctctagggac
    51121 ttgaacgact gtaataccag acttgaggac atcatttttt gctgcatctg ttccatgcgg
    51181 tatggcgata aagttaccca tgtaaacaga tagctcttta tctcgctcaa tcatggcttc
    51241 aatatagtct tcattaacat atccactctc ataaagaact tgcccacaat aacaaatagc
    51301 ttcctccttg ttagaaaatt gtttattaag cttaatcaaa tgtttttcaa gtttcatatt
    51361 agttctccaa tttcttaatt ttttcgttaa aaatagtatt tagcatctga taaataatgg
    51421 attgatttcc cgtcttgtaa atctctgtat aaagatgatt ttcaataatc gactgactga
    51481 tagctgtcat taaatctctc gcttcctcgc tagcttcttt agacattagc attagcagac
    51541 accttttgac ctcttcttcc tctcgtttca ttgacaatgc ggagataggt agtttgagtt
    51601 caaacatagt aaaactattt attgttactt tgctagactg actatgtaaa agcaccagac
    51661 cagtattagg aatagccata ggactattct ggaagtgaga taacaatttt cttgttaggt
    51721 aatctctgtc actcacattc ttctgatatt ggatgatttg ttctaccgtg tgctcaaatg
    51781 attgattatt ctccaattga accaactcga attgactcaa aagctgacta ctagatatta
    51841 aataatcttg caagtcataa cttttctctg gagcgatagc atcacgcgcg acaattgtac
    51901 gatgtgcctg tacatactga agtcgttcct gtaattcaag caattctttg acggttggaa
    51961 aactagaaat tacatcgatt tcctgattag tcagcggctt ggtagataaa atataatcat
    52021 actgactgag atcaatactg tggtaatcta ctagagactg aatatctatc aactctacaa
    52081 aaggagcaac actcttaatt ttactgacta ataaatctct agtgacccga cgttcatccg
    52141 ttaaaagcaa aacacggact ggataaatct ctggactacg gcctaagcta gagataaaat
    52201 gtagggcaat catgccatac tcatactctg tatgaagata tttcggaaaa atatcattca
    52261 ctaaaagact gatgactgta taaagaaatt tattcctttc aactaaaatc tggacagatt
    52321 ctggcaaatt ttcaccctga aaaaggatag ggactcctaa actgagccga atatgatgga
    52381 aaagaaaatt gaataaaacc ttgtccttaa aaaagtcaat cttggtatac atggaaaccg
    52441 tatcaatcag atttgaaata ttgtagaaaa attcaccatc aaatttctcc gtaaagagcg
    52501 gattgtcctg acgtttaatg attaattcat ccaagatgct cgcaaaatag ataatttcct
    52561 gaatactata aaattgtgca gtctgcttag agtaagtttg aaaaattttt tgagaaattt
    52621 ccaaagcctg cttactagta ttaggtgaat tttcaatgtt ttgctcctga cctataagag
    52681 ataacaagat cgcaaaaaac atcttcatcc tagcatccat atctggaaaa cctgacagtt
    52741 gcttattaac aatctgactg gccagcctag ttctatctgc ttctaaaata tcaaagctcc
    52801 caaaattacc ggttgaaaaa tctgctactg agatacagtt tgtcagtaaa atagccaaaa
    52861 atcttctctt accaactgaa tcaccagaaa tccgataacc tttttgtcgt tcaattttca
    52921 gatcaaagtc taaaagacgc ttatcaatat ctgaaatatc ctgaataata gttacattac
    52981 tgactttcgt gcactcttgc aatgcttcat tggtgacaaa accactctca gtcagaaggc
    53041 gataggtaat caactcttgt ctttcttggg gactatactc aactaacact tcaagttctg
    53101 tcggcaaatc atccaactct ccagtcaaaa tatagtattt cccatgcttc gttatttcga
    53161 ttccatattg ctccatgcta tctgtcaaat ctgataaagt tcgataaatt gttctagatg
    53221 aaacctgtaa gatttcagtc atatcttgca ttgaaagctt ccctacatgt aggaaagcct
    53281 tcaataattg ttcttctcgt ttggttaata gcattcgtaa tttagaaacc tctagttcta
    53341 tttgtacatt ctagcagcca ttttgtcata ttctggtgtt gttactaaac tatccacaat
    53401 aagaaattga gaattcggtg ctgcttgctg cacttctgcc tgtaaagaaa tagttgttac
    53461 aatcattatg tttttagaat taaattcacc taattctgaa attttggcag tagaaactgg
    53521 aatacgaata ttcttgtttc taaagatagc ccgaatcgtt tcacagccca tagttgcagt
    53581 tccctgtgct ttaccataag caactactac agcatcaata tggttaaggt caatttcctg
    53641 actatctact ggtgctgaag ttggtatatc tccttcaatt tctgctattg gaaaagctcc
    53701 tgttaatgaa gctacaattt catcataacg aggggacgct aagaaattat caacagaaac
    53761 atgaatagca cttggactct tgtctttagc tcttggtgtc agttcttcct gagtaacaat
    53821 taatgttttt ggtgtatcaa gcaaatttga gattgcctga ttagatactg gaatctctag
    53881 acctgctttt ttaaccttat ctcgaagaat actagctccc atagcagagc ttcccatacc
    53941 agcatcgcag gcgaaaatga ttttttccac tgagtctgtc gaaacaactg catcaacaga
    54001 agttgatact aactgacctt tagactgagc cttagctgct tgggtagccg cctgagcagc
    54061 ttcgagcgaa tcctcagttg acttgtctgc atgaagaata agggctgcta caaggaaaga
    54121 aacaactgct gccactaaaa cacctaaaag aacatttaga tgaggccaaa caccttttgg
    54181 cgccgtagcc ataatcgcaa taatagaacc tggtgaagct ggagatttaa gaccagcgtc
    54241 taagagttga aaagtaaaag ttccagagat acctcctgcc atagcagcta aaaatagagt
    54301 aggcttcatc ataacataag gaaagtaaat ttcatgaatc cctccgaaga aatgaataac
    54361 cattgccccc caagaagaag atttagcaga acctttaccg aatacagcat aagctaatag
    54421 aattcccagg cctggtccag gattagcttc caataggaag agaattgact taccagcttg
    54481 agctacctgt tctactccca gaggagtaaa aatgccatga ttgagggcat tattgaggaa
    54541 aaggacttta gccggttcga tgataatatt agccatagga aggaggcgag cattgacaat
    54601 agcctcaaca ccattcccaa cagctccagt aagagtcgat acgactggac cgattgcgta
    54661 gaaagccaaa agcaataatg caaaaccaac gagaccagct gagaagttat taactaacat
    54721 ttcaaatccg ggacgaattt tttcctggaa cttctcatca aatttcttga tagtccatcc
    54781 tcccagtggg cccattatca tagctccgat aaacatagga acactagaac ctgtgattgc
    54841 accaacagta gcaatagctc ctacaacggc accacgttgg ccatggatca tatatccacc
    54901 tgtgtaacca atcaggattg gcaataaata cgttaacata ggaccaacaa cagtagctaa
    54961 ctgttcattt ggcagatagc catcagcgat aaagagggca gtcaatactc cccaagcaat
    55021 aaatgctcca atattgggca taaccatatt tgaaagcgat gtccctagtt tttgaaccct
    55081 gactttcaat gatacttttt cttccattag atcatcctcc ttttcttaaa actagtatat
    55141 acaaagttaa aaacctttaa aactaaagtt ttgtcacaga ttttgtgtca aaacattact
    55201 tttgacgagg ctgggcaaaa aggcttaaaa attataaaac gcatcatatc aggtgtacat
    55261 gaactacacc ccaaaagtta gacagaaaaa atctaacttt tggggtgttt ttattatgaa
    55321 attaacttat gatgataaag ttcagatcta tgaacttaga aaacaaggat atagcttaga
    55381 gaagctttca aataaatttg ggataaacaa ttctaatctt aggtacatga ttaaattgat
    55441 tgatcgttac ggaatagagt tcgtcaaaaa aggaaaaaat cgttactatt ctcctgattt
    55501 aaaacaagaa atgattcata aagtctgaca tgaaggctgg actaaagata gagtttctct
    55561 tgaatactgc ctcccaagtc gtacgatact tcttaactgg ctagcacaat acaggaaaaa
    55621 cgggtatact attgttgaga aaacaagagg gagagtacct gagagcggag aatgctatcc
    55681 taaaaaagtt aagagaactc cgattgaagg aggaaaaaga gaaagaagaa agacagaaat
    55741 tgttcaagaa ttaatgactg aattttcgtt agctcttctt ctaaaagtca ttaaactagc
    55801 tcgttcgacc tactactatc acttgaaaca gctagacaaa ccagataagg accaagagct
    55861 taaagctgaa attcaatcca tttttatcaa acacaaggga aattatgctt atcgccgggt
    55921 tcatttagaa ctaagaaatc gtggttatct ggtaaatcat aaaagagttc aaggcttgat
    55981 gaaagtactc aatttacaag ctaaaatgcg acagaaacga aaatattctt ctcataaagg
    56041 agacgttggc aagaaggcag agaatctcat tcaaggccaa tttgaaggct ctaaaacaat
    56101 ggaacagtgc tacacagatg tgactgaatt ttccattcca gcaagtactc aaaagcttta
    56161 cttatcacca gttttagatg gctttaacag cgaaattatc gcctataatc tttcaacttc
    56221 acccaactta gaacaagtaa aaacaatgtt ggaacaggca ttcacagaga agcactatgg
    56281 tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta tggctatgag aaaacattta
    56341 aatcacttaa tcaattggaa caagccatta tagactatat tgattattac aacaacaaga
    56401 gaattaaggt aaaactaaaa ggacttagtc ctgtgcagta cagaactaaa tcctttggat
    56461 aaattatttg tctaactttt ggggggcagt acagaaaaac cttgatacta tgcgtttttt
    56521 gattgtgaag acttttatcc acctattata caaagttaag tatccatcac agtttacaat
    56581 tagccttcat tacttaaccc attcaccatt atagtttaag tagtaaccac ctactgtggt
    56641 attaacagct aaagcacctg aatcataggc atagtaccag ttaccattga cttggaacca
    56701 gcctgttttc atatctccat tacttgcatt tagatagtac caagtcgaac cttcctgata
    56761 ccaaccagtt gccatagctc ctgatgaacg gagatagtac catttgttcc caaggttttg
    56821 ccagccagtt ctcatatcac cattttcagc atctagatag taccaagttg agccttcctt
    56881 ataccagcca gttgccatag ctcctgacga atggaggtag taccacttat tacctagata
    56941 ttgccaacct gtttgcataa tgccagttgc tggatctagg tagtaccatg gagctgcttt
    57001 tagcttctct tcatcatagg taagagggta atccttaacc caaccacgtg ctagctctcc
    57061 caccgtcaat ctgttgatgc gcgaatcaaa gccaccatcc ttctgtaaat aataccaatg
    57121 accctcttca taaatccaac cagtttttaa agtatgataa ctacgctgat cttcaaaata
    57181 atagactcgt ttctctgctg ggctatcata ttcttcccca tgatgtttgt tggtattcgt
    57241 agcagttttt gcttctaaaa cttgcttgcc aacaaattct tgtaatacac catcttgacc
    57301 aaaataaaac caatctggtc taagagcaat ctctattctt ggagaaggac caatcgtaac
    57361 ccccttgtgt ggagcaggta tatattgcca gccgacaacc atctctccgg ataaaggatc
    57421 aaaataatag tacttcccat ctatcactct ccagtaggtt tcttttagat cccccttttt
    57481 gtagtaggtt cttccgtttt cttggacaaa ctgccatcct tcagaatcat ctgcaaatac
    57541 tgtactggtc cctagcaaac cgaagaaaaa tgtggctagt acgacttgca tcattttttt
    57601 aaaaagcttc attttatata tcctccaaca tcaaatccac tcaccagatg aagcgaagtt
    57661 ataaacttta ccatcgatag tttggctacc tgtaaccatt gctctatttg aattgagata
    57721 ataccatttt ccatttactt tttgccaatc tgtaagcatc ttaccggaac tgtctaaata
    57781 ataccaagta tcatttatct cctgccaacc cgtttgttta tcatgttgtc tataatagta
    57841 ccaactacca tttattttct tccatccttc aagagagtaa cctttaagaa ccgaataaat
    57901 aaatggcaaa tttcgttcat ttaatttaac tgcactgtta atttgattag ctccatctcc
    57961 taaagtatgc actcctacta cgcggtgact agcatcataa actgcagatc cactagaccc
    58021 ctctaaagta tcaacttggt aatccaagaa catgccatca tcacttaaaa cttgtttttt
    58081 atctgtatac atttgatgaa ttttaaaatt atatgataga tagcctgtga tagtcacagt
    58141 tattcctgtc aaattttttt gactagtagg aagacccaaa gtccctaatt ttgcaccaat
    58201 gggctcttct agaattaata aagccaagtc atattccctt gcattcttag aatttaaatt
    58261 tctaaattcc ttcaaataac gaacttcctt tactttgatc tttccaaata gttcttgact
    58321 tggactaaca gccggaagaa cataaatatc atccgcttct ttcccatagt catgtctgta
    58381 gtagttgtga gccgctgtaa ttaacacatt atctttaata aaattcgcac ttcccctccc
    58441 ttctacattc attccatcgg ctactccata atacttagat aaaaccatag ctgaagtcga
    58501 atacggatac tgtaaagtat tatcaatttt aatcaaatca tcattaccga taatacttct
    58561 gattgctttt ggtagtatga accatacgtt ggtgaaatct cagataatga agaatcatta
    58621 gactctggac ctttttctag tgtctcactt acctcatatt cttcacctgt actagaaata
    58681 acactcaaag cagatactgt cgataactgg ctagccaata aagtactcgc aataattgaa
    58741 atacccaatt ttttataaac agttttcttc attatcgtat cctcctaatg taattatagc
    58801 gtactattct aaatttctca atctactata gaatcaagaa atctaccacc ttctttaaat
    58861 accctccatt atcacataaa caggtaaact tttcaattaa tgactgcgct tttcaatcac
    58921 gctagaggta cttgcttgct tctttgatac taagttcagc cattctttcc ttgtttttct
    58981 caataaagca tgttacccaa gtgggattcg ttttggagta gtctcgcaga gtccagccaa
    59041 tggctttatt gataaaaaat tctgtttggt tcaagttatg aaggagaatc ttttccatta
    59101 attgagtatt ggtcttctct tttcttaaca actggtggtc aatagcgaca cgtctcagcc
    59161 agatattatc tgataggctc cattttatac tcaatgaaaa tcaaagagca aactaggaag
    59221 ctagccgcag attgctcaaa acactgtttt gaggttgcag atagagctga cgtggtttga
    59281 agagattttc gaagagtatt aagattattt cttctagttc agggtgttca tacaccaaac
    59341 tccctactac tcgatctagg atatctaccg tgtcccacaa ggattttgtc acgactaact
    59401 gctctagctt aggcaaatcg gtttccttta gataagactg cattgctttc aaatagttag
    59461 cagccacata ttggtatttt ctaggatcct tttcccagca agtgtctgca aaatcccaat
    59521 cgataatctt tgtttttttc gcttctggaa aatattttta tagagtttat ttctttcagg
    59581 caccgcaata cctagaaaag aaaattgatg gcgcatatag gcttccatgg accttgcttt
    59641 tttagagtct tttgctgctt ctagctcctc aagtaaatct gctaaactca tctaaaactc
    59701 ctcttgcccc accaaatggt gctgaaaggc atagacagcc gcctgggtac gatcgctgac
    59761 ttcaagtttg gcaagaatat tggacacgtg ggtcttgacc gtcttgagag agataaagag
    59821 gtcatctgcg atgcgctgat tttcgtagcc cttggcgatg agttggagaa catctcgctc
    59881 acgcgcagtc aattcttcat gaagttccat atgattgcgg tggtattcaa ccttcttgct
    59941 aacctcttgc tcaatggcca gctcgccagc agctacctta ctgacggcat gaagcaattc
    60001 atctgcacta gaagtcttga gcatatagcc tttggcacca gcatctaaga ctggcatgat
    60061 tttttcattg tccaaataag aggtcacaat caaaatcttg gcttcaggcc attctttaag
    60121 gattgctaag gtcgcgtcaa ttccattcat ctcaggcatg acaatatcca tgacaatgac
    60181 atctggacgc agttccaagg ccaagtcaat cccttgagac ccgttggacg cctcacccac
    60241 aacttctaca tcgtcttgga ggtcaaagta gcttttcaaa cccaaacgga ccatttcatg
    60301 gtcatctact agtaaaattt tcatctttac tcctttatca ttccttatct aacaggggaa
    60361 tacggatatc aactgccagc ccttgcttgg gagctgttaa taactgaacc gtccctgcca
    60421 tatcttcaac ccgctccttg atatttcgca gtccataact caagtcgtct aagctcccta
    60481 actggaaacc aatcccattg tccaccacct tcagttgcaa ttcaacatct gtctgataga
    60541 ggtagacatc taggcaagat gcctgggcat ggcggagggt attgctaatc aactcttgca
    60601 ggatacggaa gatatgctcc tcgattttct taggcaattt cgtcatattc tgcttgagac
    60661 taaccctaag atcactcttg tcctcaagct cttttaagag aatttgaatc ccttctatca
    60721 agctcttctg ctccagttca actggtcgca aatgcaagag caaaacccgc aaatccttct
    60781 gggcagtttc taaaatagct gtgacactct gcaactggat ctgcatcttt tctctatcca
    60841 atttcaaagc ttgctgactg atacccgata aaatcatgtg ggccgcaaac aactcctgac
    60901 tgactgtatc gtgcaaatcc cgagcaattc gcttccgttc tttctcgatg atttcctctt
    60961 cctgagcaag gctatgattt tcagcttttt gaagagcctc tgtcaaaagg ttaagtttac
    61021 ctgataagga cttgaaactg gcatccaaat ctggatctgc aacctgaacc acttcttgcc
    61081 ctgctaataa acgcttgaga ttagcctgca tttttcttag agaaagctct tcgatccctc
    61141 gccaaaacag ggctaagaga caggtcatgg acatgctgaa aaccaacaat aaaaagacaa
    61201 atttttctgt tttttcgaca tcgtacaaaa agatagacca gtcaaaatca agtatttcca
    61261 gcaagctgtg ggagaaaaaa aagacaaata ggaaggaggt gagagcaata atgacatagg
    61321 cttgtttttt catcctctaa ccacctccac atcaccaatc atagtggtca agaaaatctt
    61381 gacactcttg ttactcttga gatagtcttt tgtttcttga tgatagtgtt cattgcggag
    61441 ggctcgcttg ggctggttga aaaaagtcaa atccccatag agacagttaa cgctgagact
    61501 gacttccaca tctacaggta cgatgatttt ggtcgttcct accatctttc tgaggataat
    61561 gacattgtca tgattggtta agatgaccct ctccagatga atagtgtcct tgcccatgaa
    61621 gcgaaagaga ttgatatcat cgaattggca agtctggtag cttgaaaaat gatgaagatt
    61681 tccaaaccaa cgatttttct ccttcttaac cgtcacgacc tcttcaaaaa ccaaattggt
    61741 ctgctctttt tcctggttca tcatcgggta aagaagaaag agactataga taaccgcaac
    61801 aaaaatagct agaatcacaa aaggattgag cataacgatg aaaaagaaga gaatggttgc
    61861 cgctactaaa agaagattat ttccctcttt accagtgtag tagcgaatca aaagcaaaaa
    61921 gaggaatagt atcagcagaa aacgcgaaaa atgctctgat accatcaaaa tcagagctcc
    61981 tgtcagaaga caggcttcga taaataaaaa gattttaaat tttctcatag gttcatcctc
    62041 tcccttctat tttatcacaa ttcaaaaaag tcacctcagt ctgaggatgg aaaaaaggcg
    62101 ctggttacgc ctttttcatc tgatcatttg cttcttttaa ttttccataa agaagatagt
    62161 ctactttttg tagatctact atggtggcac agttaaggga acacataatc aagcgtaggt
    62221 ctgctttcca gccttggaca atgccaatca cttcttcaac tgtgtaggtt tcaaccaatt
    62281 ccagaacggt tcgtgacaat cccacagact tagcaccaaa aaccaagcac ttaatcatat
    62341 ccagcggatt ccgaacccct ccactaacca agagttcgac cttatctttc cattcttggg
    62401 cattgagaag ggcctgcatg gtagactgac cccattgatt gaggtaatca cgctggccac
    62461 tacgacggtt ttcgatatag gcaaagctgg tgccaccacg acccgatagg tccactgtac
    62521 gaacaccgaa ttcataggct ctttcgattg tcttggcatc cattccaaag cccacttcct
    62581 tgaggacaat aggaacggga atttgcttgc tataatctgc tagatgcgat tgccagcttc
    62641 taaacttcct ttctccctcg ggcatgagta attcctgcat gacattgaca tgcacttgca
    62701 atagaacagg attcatctct tctacagtct gaagtcctaa ctcgacaggt ttgtccaatc
    62761 caatattggt tccaaggagg agattgggat gactagactt gacagaaaaa gaatcatccg
    62821 ttggattttt gagggctgcg ctataagaac ccgttacaaa taaaatacca caggattccg
    62881 ccacctgagc cagcttttga ttgatttctc ttcccttatt acttccacca gtcatggcat
    62941 tgatataaaa aggaaagtcc cactttcgac cagcaaactc tgtcgaaaga tcgatttcat
    63001 ccagattgta aagaggcaag gaagaatgaa tcagctccac ctcatcaaag ctattatagg
    63061 aacttttctg ctcaagggca tagaggatat gctcgtcctt acgatttgtc gtcatgtcct
    63121 atcctttctt gatataagag ctcaatcccc agatcggccc aacgattttt taaggttttg
    63181 gttgattgcg catcaaaact cagggcgatg ccacagtcac caccaccagc accactactc
    63241 ttggcaacgg cctgcaaatc ttgactggct tctttcaact gtctaagcaa aggcgtgtaa
    63301 atatctgtac tcaagccttc taaaagcttg ctggctactt ctacttgctc gataactttt
    63361 tcggctttcc cctgctccaa ggcttcgacc aaaaaaacca ccgtttcttt tgaggaagtt
    63421 aaaaaatttt gattgatatt ttgcttgatt tgctgaacca tgtgactcga tacagccact
    63481 tccttggtcc atcccactaa gaaatcacat tctaaagttg gtttcacttg tgagataaaa
    63541 aatccccaat cacgctccag aactgtcgcc aagttttctt cttctaacca agcagccgcc
    63601 ttctggcgat caaatgactg gtagagaacc aaatcctctg ccacaataca ggcaaggtcg
    63661 cccatggaac cattgtctcc tcgcttgagc aagacagcgc tagtcagctt gaacaagagc
    63721 tcctgatcaa cagaaacatc atacagagcc agtaaagcct tgacaaccaa gacaacgacg
    63781 ctgccactag aacctagacc aaactttttc ccttctcgtt ccattttgcc acagatttct
    63841 agagaaaaag gtcttaaatt ctgaccgcga acagcgagga agtctcccat caaagcaatc
    63901 gtttcttgaa tcaagctgta gtcaggattg ggccttaagt ccactgcgaa atcaaacata
    63961 tctgaataga tacggtagct gtcagaaaaa gcaatctcag ccctcatata gatgggaata
    64021 tcctttatca aagctaaccg ccctggctct aaaatagcat attcacctgc caaatagagt
    64081 tttccgcaag ttttaacagc aatcatcttg actcaaatcc tttgtttttg acacaatcaa
    64141 gcgataacgc tgaccgaaaa tttctgacaa atgctccaag tctttctcct gacagaagac
    64201 cttaacattg ggaccagcat ccatggtaaa gtagcaggcc tctcctttct cacgaagctg
    64261 acgaacaaag gccatagcct cataagaggc atccgtcaga taagaaaagg ctggactagc
    64321 agtctttgtc gtagcatgca tagccagggc atttttctcc gttaattctc caatcttggc
    64381 aaaatcattt tccttgagat aaatcagcat atcctgatag tccttctcag actgacgaac
    64441 ccagtcgtcg aaagtcgtcg aggtttccac acaaagtttc atcccgtcac ggctagagat
    64501 tggttttttc ttgtcctcta gcaccaacat aatcatagct agtttcaagt ctgtctctac
    64561 agggtaaatt tctccactat ccttatccca ggctcctagt ggtccataaa aactccgaga
    64621 agaagagcct gaggcaaatt tggcttcctg tgccaactga cttctatcca atccaagttt
    64681 gaaataagca ttacaagcct tgaccagggc ggacaaacca ctagaacttg aggacaggcc
    64741 cgctgccgta ggcatattgt tttgagtatc gatacggaca aagccctcac cagctggacg
    64801 ataacggtca ataatcttac tcatcttggc atgctcgacc tcattttgta gctgaccatt
    64861 gatgtaaaat tcgtcagctg ttacattggc tggtaaaggc gacaaggtcg tctctgtata
    64921 catattttcc aaagttagag aaatactgct agtagcaggc accatctctt tttctttttt
    64981 ctttccccaa tatttgataa tagcaatatt tgcgtaggaa cgtactgtta caggctctct
    65041 atccatgtct gaacagctcc tttctcttct aatctttctg ctagttcttg tgcgtgtgtc
    65101 aaattggtta ccaaggctat gatacaacct cctagcccac caccgctcat cttggcaccc
    65161 agagcaccat ggctaagagt cgtttcaacc aaaaagtctg cctcagggct actgactcca
    65221 atttctttta aatgtaaatg cgcttgactg aggatttgtc ccagtccttc agcatctttt
    65281 tgtgaaatcg caacttctgc ttgctgggtt aattctccca aggcatgcaa aaacggtagg
    65341 gcatccttgc ccttattttg aaccacttgg atggcttcac gagtatgacc ataaacaccc
    65401 gtatcggcaa tcaccaaata ggcggataaa tccatctcaa gttctgtaaa tcctacgttc
    65461 ttgataaagc gaataggttg gtcactgaga caggtcttag catccaaacc actaggattc
    65521 atatgggcaa tcatctcagc tcgattgacc aagatttcta gtacatcatg aggcagatca
    65581 gcctgatagt agtcaaatac cgcacgaatg gccgctatgc tgatagccgc tgacgaaccc
    65641 atcccccgtt tctcagggat agccgagtca atctcacaac gaacgcaggc ttctgtgata
    65701 tccaaatact ccagtgaggc ataaaccgcc atggacaagg tatcctcctc ataaaggcgc
    65761 caaggactct ctgcagaaac taccttacag gtcacctcca cctccaaaag aggcagggaa
    65821 atggcaggat aaccgtaaac gaccgcatgt tcccctatta aaattatctt actatgtgcc
    65881 tgaccgacac caactttttt tgtcattttt tccttttact agacgaaaaa acgtcttatt
    65941 tttcatacaa gtattaattc tttcctatct attttattat attttcacaa aaaaagcgat
    66001 tgtttccatt cacaatcgct tctttcatta ttgaacccat tcgccattat aattgacaaa
    66061 atagccatct acggtcgtat tcactgccaa ggcacctgag ctataagcgt agtaccatct
    66121 gccattgacc tggaaccaac ctgtcgtcat agaacgacga aagaaactcc ataccattaa
    66181 gtaaagagga aagtcgtgag ggagcatgcg ccattgacaa cctgttttag tgacgtacaa
    66241 agtctcatta acaagtactc gtttcggcca tttataggtg cggtgtttgg agaaataggg
    66301 ttcaatctta gcccattctt gatcgtttaa atcagtatca tatactttgc gtgtcataac
    66361 tctagtttaa cattttttgt gaatacaggt tctaaataat cgaccacgaa aatttcttaa
    66421 gtggaaaacg ccttatgaag tatgctacgg gaaagttatg cacttaattt gacaattcaa
    66481 gatgtaaaaa tatatactat agtagattga aactagaata gtacacctct acttctaaaa
    66541 tattgttaga aatcgatttg actgtcctga tcgatttatc ctgttattat ctcattttgc
    66601 tataatattt gacaagttat cctaaaagta ttattatgtt gttgtgttat agattgattg
    66661 aatctaacta aaggatccta ttcaattact agaactatca catactcaag gtcagctcac
    66721 agatgagcaa ctattttggt tacaatgtct actaaattta agtcaaacaa ataatttagt
    66781 caaaattaaa aaaatagagg aacataaata tgattacaaa acagaatgta atagtgttct
    66841 acaattttta ctagataaaa ctgtaaattc tgaaggaagg atcacttctt caacagaatt
    66901 tggaaatttc gtaagtaatt tatcattcca acacggaata gctggactac tgtttcctct
    66961 aaataaattg taccccccag aactggattc taaaatactc tctatcatca agaaggcagt
    67021 gacaattaga acgacacata catatgaata tcaatactca ctgctatttg gtgatgcagg
    67081 ctatctatgg ttactcctac atttattttc tatcagtaaa aatcaatact atctacaatt
    67141 agcaaacgtc accgctaaaa aattaataga gaattatgat actctagagg aaatagactt
    67201 tgcattggga aaatctggtg tcctattatc attaataaaa tactatcaat ttaccaatga
    67261 caatactctt aaaattttca tccacaatag tataggggaa atttatcatt atttcctaca
    67321 aagagataca gccaaagaaa gcattttaga ctatagcttt gctcatggat attgtggaat
    67381 tgcatatgct ttatttgcct attctaaagt cttagaacct tctatgttct ataatgatct
    67441 ccatacattc catactgaat taaaaaaatt attagaaaaa gttacttcta atactgaaaa
    67501 tttaggaaat ttacaacttt cttggtgcaa aggaatttcc ggaataatct tatatctttg
    67561 tatgtacgat tgtgacggaa acaaagatat tattagtaaa tatcaagaat ttgtttttaa
    67621 ccatcatcta aaaatgatga caggatattg ccacggaata actagcttac tacaaaccac
    67681 tgtctacaat caaaacaaat tactgatgaa aaaaatccaa caggtaattt tagcatgttc
    67741 tgaacgagat gatcacggtt tactgatgtt tcaaggagat agtggtaaag cagatttgtt
    67801 tgacttcgga ataggaagca tggggtatat tggtgtctat taaataataa attcccattc
    67861 gatgtgcaga cataaggaga aaagtatgaa attattttgg acaaacaaca tatatagaca
    67921 gttgctgcta aacagctgtt tttcatcatt cggcgacagt attttctacc tcgccattat
    67981 caattatgtg gctcagtaca atttcgctcc gctagcgatt ttactgattt ccatttcaga
    68041 gatggttccc ctactatcgc aactctttct cgggattcta ggagattttc aagaaaatag
    68101 agtcaaacac gcactctgga ttgccaaaat caaaatcctg ctctacgcta ttttgacagt
    68161 atttctcgtc ttgtcgccct tttcattagt ttcagtcatt atgattgtca tcatcaacct
    68221 catctctgac accttgagct acctgtctgc ctacatgatg aacgccctct acatcagtgt
    68281 aattaaggac aacctgcatg atgccatggg gttcaggcag tctctgatga gggttgtccg
    68341 tattgtcgcc aatctggctg gcgcattcct tatcaatgtt ataagtattc aaactatttc
    68401 ccttatcaac actctgactt ttgtcattgc ctttttgggc ctgtatgtta ttcgacatac
    68461 cttgtatgag gttgaaaaaa ggattgaaat gtcacataca gcactgagtt ttaagaaata
    68521 ttttcaacat cttaaacagt cgctggctgt gctcctgagg ttaaaagata ccgtcatact
    68581 actgtttctg acgaccagta tgattgccat cttggatgtg tcccctcggc tgattgccct
    68641 ccgcttcatc caacagacac tagcacaact gagcattggg caactcctcg ccatgctctc
    68701 catcatcatt tcttgtggag ctatccttgg caatatgacc agcagtaatc tatttaaaaa
    68761 tatccgtttc acgcacctct tggttttctg tgagatttcc ctattggctc taataactag
    68821 tatcctttgt caagcctata tcgtaatttt catgaccagt ttcatcagtt ctacgattat
    68881 cggcattctc agccctcgcc tacaagcagc tgtctttgcc catatcccca gtgacaagat
    68941 ggggacggtg ggctctgctc tgagcacagt agacattctc gccccgtccc tgctctccct
    69001 attagcccta tccatagcat cgggcgtttc ggtgcagtta gcattgatat ttttgtatct
    69061 tattttaatt gctcttatct tttgtcaatg gttagtcacg ttcaacactc ataactaacg
    69121 aaaaagcatg tgtagatttc acatgctttt aatctcccca atcgtcaggt caagtacaac
    69181 aaagtcactt ctttgattaa gcgagtgttc taatataatt ataagcgccc tgtcattacc
    69241 gaacccattc gccattatag ttgacagaat agccatctac ggtcgtattc actgccaagg
    69301 cacctgagct ataagcgtag taccatctgc cattgacctg gaaccaacct gtcttcatgt
    69361 ctccattacc tgcatttagg taataccaag ttgagtcatc tttcacccag ccagtcacca
    69421 tggcgcctga cgaacggaga tagtaccatt tgttcccaag gttttgccat cctgttttca
    69481 tatcgccatt tggctggtct aaataatacc aagtggtacc ttcctgatac cagccagtgg
    69541 ccattgctcc tgaggaacgg aggtagtacc acttattacc tagatattgc caacctgttt
    69601 gcataatacc agttgttgga tctaggtagt accatggagc aggtttgctt ctatcaatgt
    69661 caatagtaac atgaaaatct tgagtccaac ccttagcaac ttcaccaatt ggtagtggat
    69721 tgtaagaatc atcaccaaaa tttcctagct tatttaaata ataccaattg ccgtcttcat
    69781 aaatccagcc tgtctttaca gcataattat tatcaaaata ataagttctc ttttcagcag
    69841 atagaggata ttgttcaccg tatacttttc ctgtattttc agacgttttt gcctctagta
    69901 cttgtttatc tgtttgttct aacaaagcac catcttgtcc aaaatagtac cacttctcct
    69961 gaaggccaat ttcattaact ggttggttat cgaataaatt atcacgataa cctgttccag
    70021 gaatttctaa gtattgccaa ccgacaacca tctctcctcc atcaccaaaa tagtaggttt
    70081 taccgtctat tttatgccaa tagattgctt tatgatcatc ttttacataa tattttctat
    70141 tatccttatc aacaaatcgg ccacctgtgg tattcgcaaa taccgtattt gtagctagca
    70201 aaccaaagaa aaagactgct agtagaactt gcatcatttt tttcaaaatt ttcatctata
    70261 taccctccta aaacgattgt agcaaagacc cgactgcatg tcaatatata aaaactcctc
    70321 aaaaaagcag ttacacaact gcaactgctt ttctattctt gcatggtgta accaacacca
    70381 cgcacggttt taatgtagct tttttggcct ttaacatcaa gcttgctccg tagatagcgg
    70441 atatagacat ctacgatatt tgtctcggtc gcactttcat acttccaaac actttccaac
    70501 aattgctcac gagtcaatac tttcttgctt cccataagtg tcgccaaaag gtcatactca
    70561 cggcgggtca gagcaatcat ctcttcacca cgataaaccg tgtgatgttc aacatctatc
    70621 ctaagattgc ggtaggtcct tggaactttc atcagactgc agtgttgatc aatgaagtcc
    70681 cgacctcgga agatcgccga aatacgcgct accagatttt cgataaggac tggcttatag
    70741 atgtatgaaa ctgcaaaacg ctgaacaact tccagctctt cttgcaagtc ttcccaatga
    70801 tctaaaatca tgatgactga ggcaggttta gttcgactca atttttctgc aaaatcctga
    70861 gccatcatat ctcccagatt aacgttcaat aaaatcaaat catagtctgt ctgaagagcc
    70921 atggagaggg ctttttgccc ctcctctacc agatcaaccc gatactgctc tttctggagt
    70981 tccaaactta aaaaatgagc tagatttcgt tctttctcaa gtaataaaat ccgtttcccc
    71041 atggctgacc tacttatttt tcgtcatacc aagagtagtg gaaggttcct tctttgtctt
    71101 tacgttggta agtgtgagca ccaaagtagt cacgttgtgc ttggatcaag ttagctggaa
    71161 ggtcagctga acggtagcta tcaaagtaag taatagctgc tgagaaagtt ggcactggca
    71221 caccagcttg aaccgcaaga gctacgatat cacgcactgc ttgttgatac ttagcagtaa
    71281 catccaagaa gtattcatcc aaaagaaggt tggcaaggtc tgcatcacgg ttgtaagcat
    71341 ctgtaatctt ttgcaagaaa cgagaacgga tgatacagcc atcacgccag atagatgcga
    71401 tatctgcaaa tggcaagttc cagttgtttt ctttagaggc tacacgcaat tgagcaaatc
    71461 cttgtgcgta tgaaatgatt tttgagaagt aaagggcttg acggattttt tcaatcaatt
    71521 cagccttgtc tccttcaaag ttgaaggcag ctggttttgg aagcaccttg ctagcatgta
    71581 cacgttcttc cttgtaagtt gaaatgtagc gtgcaaacac tgactcagta atcagtgaca
    71641 atggtacacc aaggtcaaga gatgattggc tagtccattt accagttccc ttgttacctg
    71701 cagcatcaag gatgtagtct acgattggtc catcttggcc ttcatcgtct ttacggctca
    71761 agatatcagc tgtgatttcg atcaaataac tgtctaattc acccttgttc cactcagtaa
    71821 agatttcagc catatcctct gcagaaaggc ctagcaagtg ttgcatcaag tcatagcttt
    71881 ctgcgatcaa ttgcatatca ccgtactcaa taccattgtg aaccattttc acatagtgac
    71941 cagctccatc agggccgatg taagtcacac atggtttgcc atcttctggt gctttagctg
    72001 agatttcttc aagaacatcc gaaaccaatt cgtaggcctc tttttgtcca ccaggcatga
    72061 tagaaggacc ttcaagggca cctttttcac caccagaaac tccagtaccg ataaagttga
    72121 tacctgagtt tgccaattct tcattacgac ggatggtatc tttgtagaaa gtgtttcctc
    72181 cgtcaatcaa gatatcaccc ttgtcaaggt gcggaagaag ggcttggata gtagcatctg
    72241 taccaggtcc agcttgaacc atcagcatga tacgacgagg tttttcgatt gagtttacaa
    72301 aactttcaac gtcatagctt ggtacaaagt tcttttcagg atggcaagca atcacatctt
    72361 ccgttttttc tttactacgg ttgtagatag caactgtgta accacgagat tcaatattaa
    72421 gggcaaggtt acgacccatt acggccatac ctacaacacc aaagttagct tttgtcattt
    72481 gacactcctc ttgtttcatt tgttttattt tatcattttt acttttgaaa agaaagaatt
    72541 ttgtaacgac tgcttagtag tccaagtcat ccgcatgacc agcgccattt ccgacaaaat
    72601 atcctgtctt acagttaagg gtaaagagat aggttccatc tggcttatag aggttgtaat
    72661 aaccattgcc gttaacgata ttgacacgtt caaggatata ttggtctcca gtgatatagc
    72721 cacgtgaacg tgaagttgct agaatttgtt ccaaaacacc atccgcaaaa tcccaggcag
    72781 agttattact atcatcaata gcagactgat tataggcaac acgactggca cttctttgaa
    72841 cagcaacccc tgcactcgag agacccatat tgacttcact gcgactactt ctagtctcat
    72901 ttgaactact tggttttggc tcactagtcg tatttgaact tgcttgactt gaacttgagc
    72961 tgctagtttg acttgaactt gagctagaag tacttgtttg ctggctctta ccaagactga
    73021 tagccttatc tagcacttta tcaagctccg tatttccagt tttaatatcc gtaaatttag
    73081 catccgattt ggctttggca ttggtatcca acacaccatc cacaatagct ggtttctcaa
    73141 attgagcatt gacatcttga atagccttga tttgcgttgc tagactatca tatttagatt
    73201 tggcaagcgt atgttcacga ctaccttcca gcttatcaag taaagtcttg agttgattca
    73261 gtttatcaaa ctggctattt ttcaaagccg ttttattgct atctgtgtaa aaggcgtcat
    73321 aaagtgtatt aaaatcatcc acatccgatt gattggctgt agttgattga gaagtttcaa
    73381 tttccttggt cgaacgagcc acttgacggt agacataata agcactgaca caaataatta
    73441 ctgatacaag cgccaaaacg gtcaaaataa agcctttttt acttttcttt tctgagtcct
    73501 cttgatccag acgagaaagg ttttgctcct cttccacttc ttcagtcatt tctgttggat
    73561 tttcatcatc tagcaataga ggatccaagc cttgctcctc atcgtccaga ggcaagggta
    73621 gtaagatgtc ttcagaagat ggaacttcct ccgaagaagc ttctgacttc tctacagcct
    73681 cacgcatctc ttgaattaaa tcatccagac tctgagtttc aacgaactcc tcttttttgt
    73741 attgacgagt cgcaaactta tccgcctcaa tttcatctct gtgttgctta acatacttgt
    73801 ccaaaatgga atcctcaggc aagactcctg cttccacttc ttcattttta cgaatagctt
    73861 gaccaactgt tagctctttt gcttcatcaa aatcaaattg cggttcttga ccttcttttt
    73921 tatgacgatt tcgtcttttt ttactcatga gtatcccttt ctattttacc tcttgccgtt
    73981 tgacacgctg accaaaatat tgatatagat ccactttcaa ggttccgttg tataacttac
    74041 gcttcttatc tgcttggcta ccatacttgc tttcaaaagc ttcatcacta gtcaggataa
    74101 atttgctcca agttttcagc ggtgcaaata cttgccccat ctcagcatag agcttggtca
    74161 cccctgcatc atctgacaaa cgttcaccat aaggcggatt ggaaatgatt actccattga
    74221 ttttatcgga acgtaaatcc tgcacgcgca tctgcttaaa agtaatgtct cctgcaacac
    74281 cagctgcctg agcattggcc ttagcaattt ccaccatgcg agcatcaata tcacagccca
    74341 tgatatccag ctcaagctca cggtctactt ttttagccgc ttctgtgcgc acttcttgaa
    74401 tcaagcgatc gctgatccag ttccattcct caaatgcaaa agagcgacga agacctggcg
    74461 ccatctttct agcaatcata actgcctcaa tacagaaagt ccccgaacca caggtcggat
    74521 caatcaaagg cttgtctgga taccagttag aaagttgtaa aatggctgct gccatatttt
    74581 ccttgatagg agcgccacct ttttcggtac gataaccacg tttaaagagg ctagacccgg
    74641 tcgtatcaat catgacagtt gccacatctt tgagaataga gacctcaatc ttaaactctg
    74701 ggccattctc catcagagga accccttctg ggcgagcata gtgtttctgc aatttcttga
    74761 caacagcttt cttagaaata gcctgaacac tgggctcatt gtgaagtttg gacttaacac
    74821 atttagcttt tgaaatcggg aaccgagctc caagtggtaa ataattttcc caatctaaag
    74881 cgaaaactcc ctgaaatagc tcttcaaaag tcttagctgg gaacgttcct acgataattt
    74941 tgatacgatc tgctgcccga agccaaaggt tggtttcgat aatagctctc acgtctcctt
    75001 gaaaacgaac acgtccattt tcaacctgac aatcgtagcc caactctcgc acttcacgac
    75061 caacgacagc ctcaagccct gctgccacag ttgcaattaa attaaattct tttttcatgt
    75121 tacagtcttg caagaccttt ctatatgtcc actttaaaaa atgaggttga gaaaatttct
    75181 cagccccaac ctatatgcaa ttttctataa gccatgtttt gttccagaag tgactaggac
    75241 cacttccttc gataatcatc tgtctaccac taacagctct agctgatagc agtcagaata
    75301 ctacgttcgt ttccgcgtac tccatgcccc gaccaaaatt tgggttgcta gcttgagggg
    75361 tttaccgcgt tccactctct ctgtttccag aaagactccg tcactgtggc actttcaagc
    75421 ctactctggc ctatccaagg acttagccat ttcaactgcc gtaacgattc ctcgtcccta
    75481 ggcttatggt ttcgcctagc acaaacacta caggcatcac agcctgtgct agcatggact
    75541 ttcctcatga gaagcaattc tcctcacgcg attatccaaa aattgcacat ctcaaataac
    75601 tacttaaaaa tctgagttat ctaaaatttg tttaccaaaa acttcttttt ccaatctatt
    75661 caggcgtttc aaaatatcaa aattcgtcat agaacttgta attgccgctt caaggggttc
    75721 tgcttgaact ggtgaaggtt tcggtttacg agttaattct tccttcaaat ccgcaatttc
    75781 ctgacgaagt gacttgacca aggcagcata ggtttcatag tccttgatga catcgtccaa
    75841 aaactcgtca acttctactt tattatagcc acggacttca cgtccaaact cttgttcaaa
    75901 aatatctttc gctgaaaaaa taatacttgc catgtctctc tccattctcg cttgctagta
    75961 ttattatata aaaaaaggca aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt
    76021 ttcagcaagt tcatttaatt gatcaaatgt taatctcttt ataaaatagt cctcttgatt
    76081 tttcatcttt tggtaaaaat aagctagttt cgtttcattt tcttcatcat aaaaaagata
    76141 ggaactagtc gtgttttcca gcaaaaactg ctggtaatct cttaactgcc ccttgtgttc
    76201 atagcgagga taagcatatt tgacaaagtc tacctgctta aagcgactca gtttcatctg
    76261 attgccttca ttccaatttt ccccatgggt ttcaaaagca aaaatggtgg ccaactggaa
    76321 accgtattcg gttttcatct cctgaacaac ctctaaaacc caatattcaa accccaaact
    76381 tcctgtaaac acaagccaag acaccccatc tgctgccata gcctctaaat ctttacgtat
    76441 cgctttttta atcaatttaa gacgaggatc cttatcagaa aataaaccca aatcaaaagc
    76501 agaatagcct aaaaccaaag ctgtagccat ttttaaccct ttctgtgcaa attatggtat
    76561 aataaagtga tgttattgta ccaataagga gaattatggt caactatcca cataaagttt
    76621 catcacaaaa aagacaaaca tctctttctc aacccaaaaa tttcgcaaat cgaggaatgt
    76681 cttttgaaaa gatgatcaat gctaccaacg actactattt gtctcagggc ttggctgtta
    76741 tacataagaa accaactcct attcaaatcg tacaagtgga ctatccacaa cgaagtcgtg
    76801 ccaagattgt tgaagcctat tttcgacaag cttcaacgac ggactattct ggcgtttata
    76861 atggatatta catcgacttt gaagtcaagg aaacaaaaca aaaacgtgcg attccgatga
    76921 aaaattttca tccacatcag attcagcata tggaacaagt ccttgcccaa caaggaatct
    76981 gctttgtcct tcttcacttt tcttctcagc aagaaaccta cttattgccg gcattcgatt
    77041 tgattcgctt ctatcatcaa gataagggac aaaaatcaat gccacttgaa tatattcgag
    77101 aatatggata tgaaatcaag gctggtgcct tccctcaaat tccttatctc aatgttatca
    77161 aagaacattt attaggtggt aaaacaagat gaacaaacca acgattctgc gcctaatcaa
    77221 gtatctgagc attagcttct taagcttggt tatcgcagcc attgtcttag gcggaggagt
    77281 ttttttctac tacgttagca aggctcctag cctatccgag agtaaactag ttgcaacaac
    77341 ttctagtaaa atctacgaca ataaaaatca actcattgct gacttgggtt ctgaacgccg
    77401 cgtcaatgcc caagctaatg atattcccac agatttggtt aaggcaatcg tttctatcga
    77461 agaccatcgc ttcttcgacc acagggggat tgataccatc cgtatcctgg gagctttctt
    77521 gcgcaatctg caaagcaatt ccctccaagg tggatcaact ctcacccaac agttgattaa
    77581 gttgacttac ttttcaactt cgacttccga ccagactatt tctcgtaagg ctcaggaagc
    77641 ttggttagcg attcagttag aacaaaaagc aaccaagcaa gaaatcttga cctactatat
    77701 aaataaggtc tacatgtcta atggaaacta tggaatgcag acagcagctc aaaactacta
    77761 tggtaaagac ctcaataatt taagtttacc tcagttagcc ttgctggctg gaatgcctca
    77821 agcaccaaac caatatgacc cctattcaca tccagaagca gcccaagacc gccgaaactt
    77881 ggtcttatct gaaatgaaaa atcaaggcta catctctgct gaacagtatg agaaagcagt
    77941 caatacacca attactgatg gactacaaag tctcaaatca gcaagtaatt accctgctta
    78001 catggataat tacctcaagg aagtcatcaa tcaagttgaa gaagaaacag gctataacct
    78061 gctcacaact gggatggatg tctacacaaa tgtagaccaa gaagctcaaa aacatctgtg
    78121 ggatatttac aatacagacg aatacgttgc ctatccagac gatgaattgc aagtcgcttc
    78181 taccattgtt gatgtttcta acggtaaagt cattgcccag ctaggagcac gccatcagtc
    78241 aagtaatgtt tccttcggaa ttaaccaagc agtagaaaca aaccgcgact ggggatcaac
    78301 tatgaaaccg atcacagact atgctcctgc cttggagtac ggtgtctacg attcaactgc
    78361 tactatcgtt cacgatgagc cctataacta ccctgggaca aatactcctg tttataactg
    78421 ggataggggc tactttggca acatcacctt gcaatacgcc ctgcaacaat cgcgaaacgt
    78481 cccagccgtg gaaactctaa acaaggtcgg actcaaccgc gccaagactt tcctaaatgg
    78541 tctaggaatc gactacccaa gtattcacta ctcaaatgcc atttcaagta acacaaccga
    78601 atcagacaaa aaatatggag caagtagtga aaagatggct gctgcttacg ctgcctttgc
    78661 aaatggtgga acttactata aaccaatgta tatccataaa gtcgtcttta gtgatgggag
    78721 tgaaaaagag ttctctaatg tcggaactcg tgccatgaag gaaacgacag cctatatgat
    78781 gaccgacatg atgaaaacag tcttgagtta tggaactgga cgaaatgcct atcttgcttg
    78841 gctccctcag gctggtaaaa caggaacctc taactataca gacgaggaaa ttgaaaacca
    78901 catcaagacc tctcaatttg tagcacctga cgaactattt gctggctata cgcgtaaata
    78961 ttcaatggct gtatggacag gctattctaa ccgtctgaca ccacttgtag gcaatggcct
    79021 tacggtcgct gccaaagttt accgctctat gatgacctac ctgtctgaag gaagcaatcc
    79081 agaggattgg aatataccag aggggctcta cagaaatgga gaattcgtat ttaaaaatgg
    79141 tgctcgttct acgtggaact cacctgctcc acaacaaccc ccatcaactg aaagttcaag
    79201 ctcatcatca gatagttcaa cttcacagtc tagctcaacc actccaagca caaataatag
    79261 tacgactacc aatcctaaca ataatacgca acaatcaaat acaacccctg atcaacaaaa
    79321 tcagaatcct caaccagcac aaccataaca tttatcaccc agatttttct gggtgatttt
    79381 gtcatagcac tattgtattt atgtgcttaa caaaagcctg agaagacatc ttctcaggct
    79441 ttttctgtac tataaacctc attggaaaag atagagactg cttccgtaat cttgttaaga
    79501 ggttttacta aatactagtc tttcttcgtt tttactacaa agagagcaga tagggctagg
    79561 ctaacacctg ctaggaagag ggctgtgtca gattgactct cacctgttgc tggcaagatt
    79621 tgtgcaggtg tttctggtct agctatttct tgcttataat ctggcgtctt accttgctcg
    79681 gaagctaaag agttaagttt aaactcaggt ttctctacaa ttggagcatc tggtttcgta
    79741 gcagaatctt ttaattggtt gagataatct gcaaagtatt ccaccattct ttccgtcaag
    79801 agatggttat ccgtcgcata tttcatgctt gcctgaacgc tagctacttc ctcttgattg
    79861 tctttgtctg ttaatttctg aaccttagcc aaagctgctt catagcctga caagtcaaga
    79921 ggtgtttctg ctacctgtgg acgagtaaag ataagttccg ctgcagattg gtatttatcg
    79981 ccaccatctc cgtaagtctt agtacctgta aggacaattt tcttagcctt aattgtctta
    80041 ccaaaatcaa tgtcttttgg cttattgtta tctggccaat cagttgcagt aaaggtatgc
    80101 tccttgccag actcatctgt cacaacaagt ttcacatcac gcaagttacc atttgaacct
    80161 gatccacgtg gaacataacg aagtccagtg atttcagttg gttctttcaa gaccatggtt
    80221 gcaggcttgc ctacatctcc accattccaa gatgtatgcc atagactaga cacattgcca
    80281 tcaaaggcat tctcaagacc ttcacctggt tgagctggcg catccaaact ttcaaagtca
    80341 tctgctacca aagccgttct cttctgaacc aaagcattct tcaaggcttc aatcttggca
    80401 atctctgcac gcgcttcttc cacactgata tcatcatcgg cctgactgag gttaaagacc
    80461 gcctctttca aagcatccat agactctttg gtgtagttag tcatggcaac cgttggcaag
    80521 tagttcttca gagcattttc tgtcaacatc ttacctgtta gggtaatttc ttcgatttga
    80581 agattatcca tcatgaagtc gttataacca cggaagttgg catttccacc agaatcacca
    80641 cgagtattac ttgcatttcc agttgagtag atacctaccc aagtatctcc tgtttctgca
    80701 cctgtcacaa ggaaggttgc cttcttggct ttcttagaat ctatccaagt atttggcaat
    80761 tcatgcattt ccaagttgct tgcttgagtg ccacgacgac ctgactggaa ttctccctta
    80821 ccgactacaa aagcataggt attgtctgaa cctgcttcgt attcaaaggt tacacggtag
    80881 gtcttacctg cttcaaaacg gaagttttgc ggaatagttt ggtaaaccaa gttacgacgg
    80941 ctcactagtc catttgtctt gagtgaccaa tttccttcga taacatcatc gactttctta
    81001 ccattccaac cacgttgtgt atatggatcg tgtttttcag acaagtgagt gcggttatct
    81061 tcaacacctt cgacaccacc cactacaaat gggaagatac cctgagcaac attttcaaag
    81121 tcttgcttga aggtgccttc acctgtatca tgcttgtctc cgtacatgct tgaattgttt
    81181 tcaaaggtac gaatttcatc aaagtaagtt gcttgatcac cagcttcacg actcaaagtc
    81241 agagtaacat ttgagacgtc cgatcctgtt gtaaagaagg cgtacatgtt ttggaagtaa
    81301 cttgtatcgt caactgtagc attgtcacga cgtgtattgt gggcgtaggc cttaacatag
    81361 ttgagcgcga gagacttatt ggtataagta gtcacttctt tttcaccagt attcacagtg
    81421 atacttgcct tggcattact acggttatct acaccaacat aaacggcata cttggtattt
    81481 ggtttcaagc cagttaattt ctgagtgaga ctaacttttt ctttgtttcc ttgaatacga
    81541 agcatatcgt ttgccccttg agacttgaca atttctgcct tagaagcatc gcctgaaatg
    81601 gtccaatgtt tcaaggtacc gctattaaat ccttggtcat agatgtgcat gccttcactc
    81661 catgacattt caggattagt ttgtttcgaa cgatagagaa cgtatggttg atttgctaga
    81721 agatctaggg taattttacc atcttttaca gttagttctt gctcttctgt cttaccttgg
    81781 tcagttagct tgtaaaggta aaccttgctc tttgcccaat cgcttggaag ggtccaagtt
    81841 gttgcaccgg cctgcgtatt gaagtagtac atcttttcct tattagtaga aagtttctta
    81901 ccatttgcat cccagttcca aggagtcaag taagctgaac catcttggat gacacgtccg
    81961 ttgagagtta ctgtacgttc gcgatattgt gggctattga catcatttga cttacgagtt
    82021 acaactactt tattattgtc agcatctacc aattccactc gcatttctgg agtccattta
    82081 taggtgctac cgttatcggt catagtcacc ggtgtaccat tttcccattt acttacagtg
    82141 aagtgttgga agtacttagt catgacgtca tgggcaaata agttggttac atagccattg
    82201 tagtcacttc ttccttgcca gccttcaaag tctttcatgc tgtagccacc tagcagtgga
    82261 tagttggctg caccaccata acttctgtag tccccaaccc aagcatcttt ttggtggtta
    82321 cggataaagc gggtgatggc actgttgata cctttattgg tgtagccacc gtaggtcaag
    82381 tcagctgccc agtgatggaa ggtagagtcg tactcaccac catggcccca ctcgatcgca
    82441 aagcgccagc cttgtttgtt aatttcttta gcaagaacgt gggtagccca ggcaccgtta
    82501 tcacctgatt gaccattacc ccaaacgtcc acatagataa agtcgagacc gtcaccaagt
    82561 tttttcttca aatcttccca acgtgccaaa cgaccatgag ctaggtcata ggcagcatca
    82621 atgttgatac cttgatctag ccagttccaa ccatagctat agcttccatc tggattctta
    82681 cggagaattt tttcattgaa gtatttagac tcaggataag tttctgaagc gttaacgtgg
    82741 atacctagat gagctccata tttcttagcc ttctcaatta gggtcttgaa gtcttcgaca
    82801 ccaccgatac gcttaccaat atcagcatag ttcaagtgac cagagtcatg accttcacta
    82861 ccatatcctt taaggagaac accttgccca agaccatctg tgtggagatt gattttcttg
    82921 ataccatcca aggtcataag gaatgggttt tgtgcttgag aaccaaagtt catcgcgata
    82981 cggtaagctg tgatatcctt aactttttcc caaccttgag ggttgttcat aatgctacga
    83041 taagcaatgg caccatcttg ccaatcaact ttcttgtctg cattggcatc ttcagtgata
    83101 acaaccttag cacttggaag ttccttcgtg tattctggga aaacaatgcc cttataagct
    83161 ttttcccatt gccattcaga gctgtggatt cctacatagt tggcatttcc gactgtttct
    83221 ttataagctg tcaaacgagt ccagtcattc gaaccaccac catagctgtt ttgagagtta
    83281 ctccaaacac cagcagcaag cttatctgta gaaacaaatc catacatgta acccttagcc
    83341 aaatccttca ttggattggt tacatcgata tgatcatctc cgctgacatg cgtattgttt
    83401 gacatggttg ccccatcaaa cttagcacca gtttgatcac tagaaacaga gactaaagca
    83461 ttgccgagga aactaataga agaaagtagt tttctttcgt catcaatctt ttgacctgga
    83521 gtgacttgat tgtggttgac aatcttggtc acatcaaagt gcaattgatt gtccacaact
    83581 tgcaagcgta ctgtcatttc cgcattgatt aagtgagcat catcgcgaat cttcatcaag
    83641 tactctgctg ttgtctcatt gattttctta taagtgactt caggggtgat tcggtggtta
    83701 ttgataaaga cttggttgaa ctgttgcacc tgtcctggca aagtatgccc gttcaagctg
    83761 tattccttga cacgagggaa ggcttggtca attactgcct taagtacctt agactggatc
    83821 gtatcataag tcaccttgct atcgtcaaca accgaacctg tttctttctg ggcaggagta
    83881 tcatccgctt ttacgccttc ttgattgtct gttttaacgc tgacaaccgt acggtcattg
    83941 ccataagagc ccgccttgag aaggatcttc ttctcatttt taagatggtc attgaccgca
    84001 gctggtagag tcactgtgtc aaagagattg acatcgttat tgctggcatt tagctgaccg
    84061 tctgacttga gagtgataga gagacggttt gttgatcctg tttcaggagc agcaacacga
    84121 ctacctctat accaagtgct agttgttgga gatttatact cccagaacca gccatccttg
    84181 tcataaccga caaaaacatt attattggta tctttaaatt tcaggaagac accaaagcgt
    84241 gatttgccct tttcagaatc atctttgaag gttaaatcaa cagttgcatt tccattggca
    84301 tcaacggtca agcccttctt ttcaaacagg gctggtttac ctgcgttatc attttgagca
    84361 gttgaggata gttggttgta gcggacacct ttttcttctc ggatagtgac tgttcccttt
    84421 tgttcttttt tctctaccgt ttgccattca ggggttaccg tcttaggtgt ttcaggttta
    84481 gcagctgcag gtttatcctc ttttggtttt tcttcagccg gtttttcttt ttcaagtgct
    84541 aatagttctt cttctgtctt aggtccatct gtaacttctg gagaaccttg gtcttctccc
    84601 accttaggcg cttcaaaatc acgtccatca ttctcttttg ctgttgcaag agcagtagct
    84661 aaatcagctg gtaagttcgc cgtggaacca gactgcacgc tatctgcaag aaccggactt
    84721 gtcccaaaga atgcagctcc aatcataaca gaagcaacac ctaatgaaaa tttccgaata
    84781 ctatatttac aacgtttttc aaataatcct ttattcataa acttctaaat cctttcattt
    84841 tttagcaagc gtttacattt cctttttaaa aaatactcct tcctctgaaa gtgcaatgct
    84901 taaccctgat aaataaaaaa taattatact tttaatataa caaataatag ctgagaaagc
    84961 aataggaaac aagtaaaatt aacaaaaatt ttctctattc tgacaaaaag aggctccaac
    85021 ttttgggggt cagtacattt agaatctttc tttacaaatg taaaaaagga ttcagcattc
    85081 aagagaaata ctaaatcctt tcttatattt tgcaacagtt atttcacatg ttttgcgaga
    85141 tcttcttgag cctttttatt agactcttct ttttctttca tccatttttc ctgagctttt
    85201 tggtattcat ctacagtgac tgccttgtct tgaagttcca agtatttata caagactggt
    85261 tcacttgtac ctttatttcc tgacaatgca aatggtattg taaatggtac catcttagac
    85321 aagattgggc gccctgtacg agatgtagtt ggaataatca aagcactatc tgtcaaccaa
    85381 gcttgggctg cagcgtattt atcatagcgt ttagcaacat ctgtagtctc atcaccagcc
    85441 tcagtaacca atttttcgta gtcatataga cctacttttt tagcagctac attatcttcc
    85501 cctgagtcaa accctaaata tgttttagta ctttctccta cagatggttt gatgatatca
    85561 aggtaggttg atggatcggc aaagtctgga ccccaaccga cattatctga taaatcccag
    85621 tcttcgccag cagcattttc agcaaaatat gtaatattgt ttacttcgtc tttttgtagt
    85681 tgttgaatat caatgactac attatccgct cctaaagttg cttccaagga ttgtttcata
    85741 gattggacgc gctgaacttt tgtagttgct gtttggtcaa ctggcatatc caaatgaatt
    85801 gggaatgtca caccttctgc ttgtaaggct gatttagctt tagcaaattc agccttggat
    85861 ttttctggat tgtaaagacc atcctgagaa tctgcaagat taacatcctt ccattcatcc
    85921 ccataagtaa ccaatttctc tttgaccata tcgccaaagt ttttaccatc tgcttgaaca
    85981 aatgttggtg gaacaaagat attacgtaag attttgcttg ctccagtttg tccattcaac
    86041 tgagaggcat aggctgtacg atcaaaacca aaggcaatag cctgacggaa atccttgttt
    86101 aagagagcct ttttagtcga tgccttttgt tcgtcgctgg tcttagatgt gtatttatag
    86161 gactgacggt caatatttgt accaactaga tacgtaatag agtcttgttg agtatagaca
    86221 atattgtcct tcatactctt ctcaagctct gcgaaacttg cacttgttgg atagagacga
    86281 gctgctgtaa ggctaccatc tttaaagttt tctgcaggtt tgctggtatc ttgaccatcc
    86341 cagaatgaca atttaacttt gtcaatatgc acattgtcct tatcccagta gttcggattt
    86401 ttcgcaaatt caacagaaga tttggtcaca atggatttca acaaataagg tccattatac
    86461 aagagactac ttggatccgt agctttggca aaatcatccc cttttgagtt caaaaactct
    86521 tcattaactg gcgcaagcac acccatggtt gtttttgagt tccaaaaact ttcaggtttg
    86581 ttcaaagtgt actgaactgt ctgatcatcc agagccttaa ttcctacttg tgagaaatct
    86641 ttgatttccc cttttacata ggcatccaac cctttgattg attcttgaac aaggtaaaga
    86701 gcatctgatt ttttatcagc agcatatttt agtcctgtta caaagtcttg agctttgact
    86761 gccgcgtatt cttcaccttc agaagtatac cattttgcat ccttacggat agtataagtg
    86821 taagtcaatc catccttgga tacagaccaa tcctcagcca tagacggcac aaagttcccg
    86881 tagcgatcat tttctagcaa accatcaacc acgttactgg taatatttgc tgtcgcagcc
    86941 ttagcagttg tcaaatagtt gaggttatca gggtctgtct cataaatgta tgagaatgtc
    87001 ttctcacctt tagtgcttga acctgatcca gagcatgcag ctaaagtagt cgccgccaat
    87061 aatgtcacgc ccgcaagggc aaatagtctt gaacttttca tcattttctc ctttaaaact
    87121 ttctctccat tatagactct tttcagaaag ttgtcaacag aattttcaga atttttgtgt
    87181 taatttggta tattctgaaa agacaaaaaa ggagaagaca gtgattgtcc tctccagatg
    87241 ttagttgaca aagagccaca ttataaatct aaaataattt attttaattt aatatacttt
    87301 tgtggtaata aaacaatatt caaaaatgga atttttttca atatataagt tgccagtatg
    87361 gataaatacc aacccaagac aatcccaaca acaacgtgaa gaaaaactga gtttattccc
    87421 actttcaaca tttaggattt ttatagatat ttattaaatc aaatatagtc gtcgggactc
    87481 taacagtcgc ccctgcaact ttttgaagac caaagtgaat gatcgaatag aaaatatatg
    87541 gcagaccaaa aacaattgtc ttctttttag catattgcca gaactccttc aaatccgaca
    87601 caggtttgaa aaagtatcct gataaggcaa aaaatactgg tatatgaaat atgtagactt
    87661 gtgctatcaa caacgatagt atgttatttg ctgtgggaaa tttttccgat tgatacagtc
    87721 caagcaacac atgtcctgct aagactaaaa atatggaaaa gccttttcca aaatctatcc
    87781 aattgattct actttttgtc atatccaaac tctttctcca caacctcaag cgcccgttca
    87841 atcaccacat gcatatcgta atatttataa tctgctaaac gtccacagaa aataacctta
    87901 tcattctttg aagcttcctc ttggtactta gcaaacatag cattattttt ctcatcgttg
    87961 atcggatagt aaggctcgtc cccacgcttc cagtcagctg gatattcacg cgtgataact
    88021 gtctttgcct gtgttccata ttcaaaatgc ttgtgttcga taatacgagt ataaggaatc
    88081 tcacgctccg tatagttcac tacagcattt ccttgataat tttcctcgtc caaaatttca
    88141 tgatcaaagc gaaggctacg gtattctaac tctccgtgct tgtagccaaa atactggtcg
    88201 atcatccctg taaagacaac tttttcagct gatgcttcta actcttcacg atgagcaaag
    88261 aaatcaacac caagctcaac ttcaacgtct ttaagcatat tttcgatgat gacattgtaa
    88321 ccaccaatag gaattccttg gtaacggtcg ttaaaatagt tattatcaaa tgttaaacga
    88381 actggaagac gtttaatgat aaatggagga agttccgttg ctgagcgtcc ccactgcttt
    88441 tcagtataac ccttgattaa cttttcatag acatctggac caatcaactt gatagcctgt
    88501 tcttccagat ttttcggctc aacatccttc atatcagctg tctgctcagt aatcttatct
    88561 ttgacttctt gaggagtttt tgtcccccac atagcataga aggtattcat attgaaaggt
    88621 agattataga ggctaccctt gtaattagct acaggcgagt tgacgtagtt gttaaattca
    88681 gcaaattgat taacataatc ccaaactttc ttattagaag tatgaaagat atgggcacca
    88741 tatttatgaa cattaactcc ttctacattc tcacagtaga tattcccacc aatgtggtta
    88801 cgtttatcaa tcacttttac tttttttcca cgcttggtcg cctcataagc aaaaattgct
    88861 cctgacaaac cagcaccgac aataagataa tcgtacatct tgttctcctt tttataattt
    88921 gacgattcga ttgaagtaag gaatcttcat taacatccca acaataataa aactaacact
    88981 taaagtaaat agagcaaaaa gtaaatatgc tcctacaaaa ttaaaaccaa gcactttttc
    89041 ccacactttc ataatataag tatgtattat gaaaaccccc attgtttgat tagaaaggga
    89101 aacaatcgat tctcttcggt tttcattcaa agtaagcatg aggatagtta gaaaaattcc
    89161 taaagtactg acttttacaa ataaagtatc ataaaagtat tcagcaaata gattatggta
    89221 tatagtcttc gctatgaaaa ataatattat tggtgaaatc aataacaaaa gtatgctaac
    89281 tattttcatc caattcttaa accttgattc gatttcttct atagtgaatt gcgctatata
    89341 accacctaaa agatagtaaa aaaaccacgt ccataatcta aaagtttgta ttacatatgt
    89401 ttgtattggc atttgaagta ggatatttga taactcaaaa atcaaaccaa tagtcatcaa
    89461 taaagataaa ctgtataaat agcttctttt tgaatttaga aattgtctca aaattggcaa
    89521 acataaatag ataagtatga gtgcaccgaa aaaccaaaac tggaagaaat accccttttg
    89581 tatcaaagaa cctataattt ttttaattaa gttctctgta aagtctcttt taaacagcca
    89641 aacgataaaa gtccatgacg acactgttat taggagccat tttatttttt gcaatatgta
    89701 ggaataggta atttctctct tccccaacaa taaataacca ttgaccataa aaaatagagg
    89761 gatagaatag gttcctaagt aatataaata tgtcaaaaaa ttccatgcac ctgtctcttt
    89821 aaacccaccc atagttgtat gaagtagaac gactccaaca catgcaagca cttttagtaa
    89881 atctaagtta atatttcgaa atttgctcat tctaattttt cctgattatt tgttttaatt
    89941 ctttcacatc taccactttc agagatagaa ttgcaaaaag atagataatt ccgcctagca
    90001 ccgaaaatat taaaacattt atggttggcg aaaaatgtat agatgttttt gaacctagca
    90061 agagaccata cataacagca gatgcaagtg cagtttttgt cattgaaccg ataataggaa
    90121 cttcttttaa ataaaaacgt gtatagaata actgaatccc ccatacaaac gcctcagtca
    90181 aaactgaaac aatcgcagca cctatataac caaattgggg aagaagcaac aaattcaatc
    90241 ccacactcag aatagcggga actgtcgttg aaaccataaa ttccttattt ttattgtgcg
    90301 gaatcaagat ttgaattccc attatattgg tccaaccaat aaagaacata cggaaggtca
    90361 taatagcaat cgcatagcga gcatcttgaa aattttgccc aaggaagaaa cgaacaaaat
    90421 catcgttgac aatcaacatt cctgctatga ttgggaaaat caccaagtta tagattaaaa
    90481 aagacatctc gtgcatctta ttaacggctt tgtaatcccc agacgataaa aggctagata
    90541 ctcgtggcaa cataacactc cccagtgagg taaccaaagt cagtaaaata ttaacaagct
    90601 tcaaagcttg atcataaatt ccaacatcct ttgtcgaagc caacaccccc agcatcgtac
    90661 ggtccaaagt cacataaagc gagatggcaa tctgtggcaa gaataacaag ataactggtt
    90721 tcaaatgctt cttagcgtat ttccaatcaa aatatgattt accaataaat tgtcttgcgg
    90781 gtaaccacat gcttaattgc cctaacaatt cgaaaatggt aagaagaaat acatataagt
    90841 ataagtcatt agctgatttt acaaatagga aaatagagat tgcaccaact aacttaacag
    90901 tgatgttccg aactgtaatc tttctaaaat cctccaaacc ttgaaataac caagaaatat
    90961 ccaaaccttt tgacactaaa cttaatccca atatataagc taccggattt tgcattgaag
    91021 taaataagaa acaaagggca agataaagca aaatggatag ccaagttgca ccaaactgga
    91081 gagaataaat tccccagaaa ttcttcccaa tttccttacg atgtgctgaa atctctttgg
    91141 taccgtagtt ggcaacacca agagttgcaa gcaaggtaaa ataggtaaca atggagctaa
    91201 agtagccata cgttcctaaa tcgtcagaac taaaaaccct cgttacatag ggagtcgtaa
    91261 tgatagggag tatgatcacc aacaattgat aagaaagatt gtaggcatag ttttttagta
    91321 ttttcatttc ttcttatttc tgttcacacc tttattatta attagtaatg tactgtttct
    91381 catgacaatc tctatcgtcc ccaaaatcaa gagaatagta taaagaaatg acaaataaaa
    91441 acatataggt ctctataaat atagtagtta tcataaggaa aattattaat agcgcagaaa
    91501 acttcaaatc attcgaacta aatttattca aaataatttt aattactgga taaaagtaat
    91561 acgaagccaa cattatccct ccttgagcta aaacaacaaa aaagctattg ctatacccaa
    91621 gattatatct aacagttcta tccatatgtt gttcaatggt tctaagaccg tctgaaatac
    91681 ctaatcccca aataggactt ttctgccatg ccaaaaaacc agccttataa tcatcaaagc
    91741 gtatagttgc tgaaccagtt ccagatttat tatcccataa tattgaaaaa caacatataa
    91801 tcgctaaaat aaataaacta gaaacatatc tcttcacacc acttgttttt gaaaataaaa
    91861 catataggaa aatcaaacct attatataaa cccctgttgt tgacgtagtt gtcataattg
    91921 taataataag agtccaagtt gtgaaattcc atttttttat atgaagcgtt tgaaatatca
    91981 atgcaaggct caataccaaa ctccacatag gtgcttcagc aaaaatcccc gtatttctta
    92041 tcagtatcgc ccccaaaatc tctatttttt gtgcttcaaa atgaagatta tagtaccctt
    92101 ctactattcc cccaccattc caataattca acacataaac cgttggggat ataatatgaa
    92161 atacactacc aataagccaa aataggagag agccaattgc taaaagaaat attatacgaa
    92221 caaatttccg tatcagattt gcgatttcat taacatcata gtacatctgc aaaatcatca
    92281 taaaaatcgg aaataataca aaataataga cgaaacttgt ctcagaaatc ttaaaaccat
    92341 ttaatattac tatgagtaga ataattaata taaatattaa agaacgcgac acaatcacat
    92401 tgattgcctt catagatatt ctagagataa gcaatttcag aaaaactgat accacaagta
    92461 acagagtcgc ccatttccct agtccatcaa atccttgact agttgaatac atagtattac
    92521 aagtaataat cacactaaat agaaatatat agtccagcaa accatctaat ctaacatgca
    92581 tctatatcct gcctctctgt aacatcttat cttttatttt atagtagtaa tttggggaaa
    92641 gcagaaacaa aacacattga actttccttt tcattggaat ttttttattt tttattactt
    92701 cccaataata cggtttaatt attcttatta ttttagtaat atcgttttta ctattataaa
    92761 atgcgctatt actcaaaata aaggagccaa ttactctttt agcatttaag gctgctaaca
    92821 attccttatc tccacaatag aattttttta ttatggcttc attatgatca atcgcatcaa
    92881 aaaaatcata ctgtctatcc gaaaatgttg aattaacaat acttccctgt ctctgataat
    92941 aatgatatat aggcaaatcg gtatgagcaa ctgttttaat attcaacaaa cgctctgcaa
    93001 caacatacaa atcctcgtag atctttcctt ttggaaaaat cgttttaaat aaatctcttt
    93061 tatacaattt tccccaagca gataccgtca tttcatcgtt ataatataca gctgccaaaa
    93121 attctttatt tgtcaatatt tttacagtta ggtagtcctc agccatcagt tttttgctat
    93181 aaatatcatg agaataggtt attccccctt tagttgatac gatatctaca tcatattttt
    93241 tttgaatagt aattaacaat tctaatgcat acggttcaaa ataatcatct gaatcaagaa
    93301 aagttataaa ctctcctcga ctcttctcca aaccaaaatt tctagcatcc gaaagtccgc
    93361 cattcttctt atggaaaaca tgaatattat catacagttt cccatattca tcacatattt
    93421 ccccagaatt atcagtggat ccatcattta ctagaataac ctcaaaatct ttatacgtct
    93481 gttccaaaag actatccaac gcaaagcgca gataatccgc gacattgtat actggaacaa
    93541 taactgaaat cataccattc cctctcttta tgctacagtt cacccttcat caatctatca
    93601 aaataggttc ctgtcgcttc atttatcgga cacttataac tacacttaaa caatgcagtt
    93661 gttgataaaa ctcctgccca ctctttttca tcatactggt tagaaaaatt gtctgccaaa
    93721 aagaacaact cctgattatt ttcttcgact ttatcaatat agtttctaat caagtcattt
    93781 gtcctataac ctaattctat aatatagtca attaaaaaat aatctagcac tatatcgtat
    93841 ttcataaaat atgctacatg aaatttctct aaaaaatcaa atactatgtt ttgcttttcc
    93901 cctgacaaac aaaatgcaga ccacctacca tttgcgatat atttgggcac tctctcatgt
    93961 gtctttgctc gaatagtata aaaatctttt tttaaataat tcagttctcg tgaagaatca
    94021 acataaatag tcgaatctaa ccacactcct ccatattttg aaagcaatgt tccccttaca
    94081 acatccgaat attttataaa atctatagtt ccattctcat atttttctac tatctctgat
    94141 ggaagtgtca catattcacg gatattgttt tcatccaaaa aaacaaattt atatccgtat
    94201 ttttctgcat atttcctttg gctatcaatc gtcttctgaa ccaacttagg agcactttcg
    94261 tatccttgta tccacataga gaagattttt ctttgttcta tctccttgtg cgatacctct
    94321 ttaaagttat aggattttaa aaattggcta aaatcttttt ccaaaaaatt tatgattgtt
    94381 tcatgtttgt attgataaaa attactagct atattattga aaattttata attccctatc
    94441 cgtccccaaa acttttcaaa taatttattc cgagcaatag caggagtaaa tgattttctt
    94501 aatacaaaat actcgtttat tacttttcct atttttctca tattattttc ttatccccag
    94561 aaaatattt
//
LOCUS       DAVMCG010000004        77861 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVMCG010000004 DAVMCG010000000
VERSION     DAVMCG010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77861
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.004"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            154..1635
                     /locus_tag="VYP66_000315"
     CDS             154..1635
                     /locus_tag="VYP66_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1849931.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEHNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            1997..2998
                     /locus_tag="VYP66_000316"
     CDS             1997..2998
                     /locus_tag="VYP66_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1849932.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3147..4064
                     /locus_tag="VYP66_000317"
     CDS             3147..4064
                     /locus_tag="VYP66_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1849933.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYDYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4075..4965
                     /locus_tag="VYP66_000318"
     CDS             4075..4965
                     /locus_tag="VYP66_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1849934.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            4994..6610
                     /locus_tag="VYP66_000319"
     CDS             4994..6610
                     /locus_tag="VYP66_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1849935.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKATDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTIPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSNYLAIKQKYYDQYQANKN"
     gene            6620..7939
                     /locus_tag="VYP66_000320"
     CDS             6620..7939
                     /locus_tag="VYP66_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1849936.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8147..8219)
                     /locus_tag="VYP66_000321"
     tRNA            complement(8147..8219)
                     /locus_tag="VYP66_000321"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8184..8186),aa:Lys,seq:ctt)
     gene            complement(8484..9755)
                     /locus_tag="VYP66_000322"
     CDS             complement(8484..9755)
                     /locus_tag="VYP66_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1849937.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPVELDEEALDFIATSTNGDLRSAFNSLDLAVLSTSENDKGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10053..10268
                     /locus_tag="VYP66_000323"
     CDS             10053..10268
                     /locus_tag="VYP66_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849938.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFREDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10433..10612
                     /locus_tag="VYP66_000324"
     CDS             10433..10612
                     /locus_tag="VYP66_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849939.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10749..10928
                     /locus_tag="VYP66_000325"
     CDS             10749..10928
                     /locus_tag="VYP66_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1849940.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            10965..11417
                     /locus_tag="VYP66_000326"
     CDS             10965..11417
                     /locus_tag="VYP66_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1849941.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTISKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11708..12178
                     /locus_tag="VYP66_000327"
     CDS             11708..12178
                     /locus_tag="VYP66_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1849942.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKIGLEKGEFYPYPKY"
     gene            12197..13285
                     /locus_tag="VYP66_000328"
     CDS             12197..13285
                     /locus_tag="VYP66_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1849943.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAILFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENWLAELEKEMLEGTEDGTRNF"
     gene            13266..13694
                     /locus_tag="VYP66_000329"
     CDS             13266..13694
                     /locus_tag="VYP66_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1849944.1"
                     /translation="MELEISDFTGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13830..14780
                     /locus_tag="VYP66_000330"
     CDS             13830..14780
                     /locus_tag="VYP66_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1849945.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            14782..15525
                     /locus_tag="VYP66_000331"
     CDS             14782..15525
                     /locus_tag="VYP66_000331"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1849946.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15536..17332
                     /gene="pepF"
                     /locus_tag="VYP66_000332"
     CDS             15536..17332
                     /gene="pepF"
                     /locus_tag="VYP66_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1849947.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17579..18133
                     /locus_tag="VYP66_000333"
     CDS             17579..18133
                     /locus_tag="VYP66_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1849948.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTDFSSQYGWVHAFAHGADLLTEVVCHPDFPINRIHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDDLKEAIQSFQY"
     gene            18244..18912
                     /locus_tag="VYP66_000334"
     CDS             18244..18912
                     /locus_tag="VYP66_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1849949.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(19081..19170)
                     /locus_tag="VYP66_000335"
                     /pseudo
     CDS             complement(19081..19170)
                     /locus_tag="VYP66_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(19167..19700)
                     /gene="queF"
                     /locus_tag="VYP66_000336"
     CDS             complement(19167..19700)
                     /gene="queF"
                     /locus_tag="VYP66_000336"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEV1849950.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(20006..20320)
                     /gene="trxA"
                     /locus_tag="VYP66_000337"
     CDS             complement(20006..20320)
                     /gene="trxA"
                     /locus_tag="VYP66_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1849951.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20337..20558)
                     /locus_tag="VYP66_000338"
     CDS             complement(20337..20558)
                     /locus_tag="VYP66_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1849952.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20657..21037)
                     /locus_tag="VYP66_000339"
     CDS             complement(20657..21037)
                     /locus_tag="VYP66_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1849953.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(21181..22134)
                     /locus_tag="VYP66_000340"
     CDS             complement(21181..22134)
                     /locus_tag="VYP66_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1849954.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREKKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIESYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYGQ"
     gene            complement(22202..23409)
                     /gene="sstT"
                     /locus_tag="VYP66_000341"
                     /pseudo
     CDS             complement(22202..23409)
                     /gene="sstT"
                     /locus_tag="VYP66_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23548..24108
                     /locus_tag="VYP66_000342"
     CDS             23548..24108
                     /locus_tag="VYP66_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1849955.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            24165..25073
                     /locus_tag="VYP66_000343"
     CDS             24165..25073
                     /locus_tag="VYP66_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1849956.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            25025..25615
                     /locus_tag="VYP66_000344"
     CDS             25025..25615
                     /locus_tag="VYP66_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1849957.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25618..26724
                     /gene="yqeH"
                     /locus_tag="VYP66_000345"
     CDS             25618..26724
                     /gene="yqeH"
                     /locus_tag="VYP66_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1849958.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            26939..27250
                     /gene="yhbY"
                     /locus_tag="VYP66_000346"
     CDS             26939..27250
                     /gene="yhbY"
                     /locus_tag="VYP66_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1849959.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27302..27931
                     /locus_tag="VYP66_000347"
     CDS             27302..27931
                     /locus_tag="VYP66_000347"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1849960.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            27931..28524
                     /gene="yqeK"
                     /locus_tag="VYP66_000348"
     CDS             27931..28524
                     /gene="yqeK"
                     /locus_tag="VYP66_000348"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1849961.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            28525..29025
                     /locus_tag="VYP66_000349"
     CDS             28525..29025
                     /locus_tag="VYP66_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1849962.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            29038..29391
                     /gene="rsfS"
                     /locus_tag="VYP66_000350"
     CDS             29038..29391
                     /gene="rsfS"
                     /locus_tag="VYP66_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1849963.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29494..30240
                     /locus_tag="VYP66_000351"
     CDS             29494..30240
                     /locus_tag="VYP66_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1849964.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30250..31347
                     /locus_tag="VYP66_000352"
     CDS             30250..31347
                     /locus_tag="VYP66_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1849965.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQSMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHTIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVEAVATKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETS"
     gene            31585..31839
                     /locus_tag="VYP66_000353"
     CDS             31585..31839
                     /locus_tag="VYP66_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1849966.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSIQVHVIEE"
     gene            31843..32097
                     /locus_tag="VYP66_000354"
     CDS             31843..32097
                     /locus_tag="VYP66_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEV1849967.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            32288..33901
                     /locus_tag="VYP66_000355"
     CDS             32288..33901
                     /locus_tag="VYP66_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1849968.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            34031..34657
                     /gene="gmk"
                     /locus_tag="VYP66_000356"
     CDS             34031..34657
                     /gene="gmk"
                     /locus_tag="VYP66_000356"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1849969.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQERLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            34682..34996
                     /locus_tag="VYP66_000357"
     CDS             34682..34996
                     /locus_tag="VYP66_000357"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1849970.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            35062..37458
                     /locus_tag="VYP66_000358"
     CDS             35062..37458
                     /locus_tag="VYP66_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1849971.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMERDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFDSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQMVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNPQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37471..38406
                     /locus_tag="VYP66_000359"
     CDS             37471..38406
                     /locus_tag="VYP66_000359"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1849972.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            38399..39712
                     /gene="rsmB"
                     /locus_tag="VYP66_000360"
     CDS             38399..39712
                     /gene="rsmB"
                     /locus_tag="VYP66_000360"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1849973.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVLLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            39727..40467
                     /locus_tag="VYP66_000361"
     CDS             39727..40467
                     /locus_tag="VYP66_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1849974.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            40464..42443
                     /gene="pknB"
                     /locus_tag="VYP66_000362"
     CDS             40464..42443
                     /gene="pknB"
                     /locus_tag="VYP66_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1849975.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENSSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYALSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            42558..43316
                     /locus_tag="VYP66_000363"
     CDS             42558..43316
                     /locus_tag="VYP66_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1849976.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            43318..43767
                     /locus_tag="VYP66_000364"
     CDS             43318..43767
                     /locus_tag="VYP66_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1849977.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            43829..44454
                     /locus_tag="VYP66_000365"
                     /pseudo
     CDS             43829..44454
                     /locus_tag="VYP66_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            44522..44770
                     /locus_tag="VYP66_000366"
     CDS             44522..44770
                     /locus_tag="VYP66_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849978.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMVRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            44901..46073
                     /locus_tag="VYP66_000367"
     CDS             44901..46073
                     /locus_tag="VYP66_000367"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1849979.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            46073..47347
                     /locus_tag="VYP66_000368"
     CDS             46073..47347
                     /locus_tag="VYP66_000368"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1849980.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(47383..48348)
                     /locus_tag="VYP66_000369"
     CDS             complement(47383..48348)
                     /locus_tag="VYP66_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1849981.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKKLKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(48329..49783)
                     /locus_tag="VYP66_000370"
     CDS             complement(48329..49783)
                     /locus_tag="VYP66_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1849982.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            50159..52096
                     /locus_tag="VYP66_000371"
     CDS             50159..52096
                     /locus_tag="VYP66_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEV1849983.1"
                     /translation="MDYSKVAAEVIEAVGKDNLVAAAHCATRLRLVLKDEAKVNQAAL
                     DNNADVKGTFSTNGQYQIIIGPGDVNFVYAEIIKKTGLKEVSTDDLKEIANKDKKFNP
                     LMDLIKLLSDIFVPIIPALVAGGLLMALRNFLTSPDLFGPQSIEDMYPAIKGFSAMIQ
                     LMSAAPFMFLPVLVGISAAKRFGANQFLGAAIGMIMTTPDLGGKEAFWDILGFHVTQT
                     NYAYQVIPVLVAVWLLANLEKFFHKKLPSAVDFTFTPLLSVMITGFLTFTVIGPVMLV
                     VSDAITNAIVWLYNTTGAFGMGLFGGTYSLIVMTGLHQSFPAIETQLLSAYNNNGTGF
                     GDYIFVVASMANVAQGAATLAVYFLTKNAKTKGLSSSAAVSAFLGITEPALFGVNLKY
                     KFPFFCALAGSAIGAFVAGLTHVIAVSLGAAGFIGFLSIKAGSIPMYIIAEIMSFVAA
                     FAFTYFYGKTKAASVFADEAATATAETVTEPTVEAPVVEETDTLQNETLVTPIVGDVV
                     ALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLI
                     HVGIDTVSMNGDGFEAKVAQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYA
                     SVAPVATGSVAKGNAVIEVKI"
     gene            52245..53132
                     /locus_tag="VYP66_000372"
     CDS             52245..53132
                     /locus_tag="VYP66_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1849984.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53452..54069)
                     /locus_tag="VYP66_000373"
     CDS             complement(53452..54069)
                     /locus_tag="VYP66_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1849985.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54484..54672)
                     /locus_tag="VYP66_000374"
                     /pseudo
     CDS             complement(54484..54672)
                     /locus_tag="VYP66_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(55182..55262)
                     /locus_tag="VYP66_000375"
                     /pseudo
     CDS             complement(55182..55262)
                     /locus_tag="VYP66_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            55379..56272
                     /locus_tag="VYP66_000376"
     CDS             55379..56272
                     /locus_tag="VYP66_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1849986.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            56269..57468
                     /locus_tag="VYP66_000377"
     CDS             56269..57468
                     /locus_tag="VYP66_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1849987.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVEVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(57821..58588)
                     /locus_tag="VYP66_000378"
     CDS             complement(57821..58588)
                     /locus_tag="VYP66_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849988.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(58605..59300)
                     /locus_tag="VYP66_000379"
     CDS             complement(58605..59300)
                     /locus_tag="VYP66_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1849989.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(59305..59670)
                     /locus_tag="VYP66_000380"
     CDS             complement(59305..59670)
                     /locus_tag="VYP66_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1849990.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            59810..60283
                     /gene="nrdR"
                     /locus_tag="VYP66_000381"
     CDS             59810..60283
                     /gene="nrdR"
                     /locus_tag="VYP66_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1849991.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            60284..61453
                     /locus_tag="VYP66_000382"
     CDS             60284..61453
                     /locus_tag="VYP66_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1849992.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLGHPVYRRLLEKKIGDVAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            61454..62350
                     /gene="dnaI"
                     /locus_tag="VYP66_000383"
     CDS             61454..62350
                     /gene="dnaI"
                     /locus_tag="VYP66_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1849993.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVMNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            62347..63060
                     /locus_tag="VYP66_000384"
     CDS             62347..63060
                     /locus_tag="VYP66_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1849994.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKLRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            63074..64384
                     /gene="der"
                     /locus_tag="VYP66_000385"
     CDS             63074..64384
                     /gene="der"
                     /locus_tag="VYP66_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1849995.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            64475..64810
                     /locus_tag="VYP66_000386"
     CDS             64475..64810
                     /locus_tag="VYP66_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849996.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            64950..65285
                     /locus_tag="VYP66_000387"
     CDS             64950..65285
                     /locus_tag="VYP66_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849997.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVRH"
     gene            65470..66261
                     /locus_tag="VYP66_000388"
     CDS             65470..66261
                     /locus_tag="VYP66_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849998.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLGWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            66254..66895
                     /locus_tag="VYP66_000389"
     CDS             66254..66895
                     /locus_tag="VYP66_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1849999.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLILSRLEEKFKKG"
     gene            66899..67549
                     /locus_tag="VYP66_000390"
     CDS             66899..67549
                     /locus_tag="VYP66_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1850000.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            67560..67847
                     /locus_tag="VYP66_000391"
     CDS             67560..67847
                     /locus_tag="VYP66_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850001.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            67993..70506
                     /gene="secA"
                     /locus_tag="VYP66_000392"
     CDS             67993..70506
                     /gene="secA"
                     /locus_tag="VYP66_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1850002.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            70587..71618
                     /locus_tag="VYP66_000393"
     CDS             70587..71618
                     /locus_tag="VYP66_000393"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1850003.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQALINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            71620..72651
                     /locus_tag="VYP66_000394"
     CDS             71620..72651
                     /locus_tag="VYP66_000394"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1850004.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            72690..73058
                     /locus_tag="VYP66_000395"
     CDS             72690..73058
                     /locus_tag="VYP66_000395"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1850005.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSRAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            73048..74151
                     /locus_tag="VYP66_000396"
     CDS             73048..74151
                     /locus_tag="VYP66_000396"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1850006.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            74170..76185
                     /gene="recG"
                     /locus_tag="VYP66_000397"
     CDS             74170..76185
                     /gene="recG"
                     /locus_tag="VYP66_000397"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1850007.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERETDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMIETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEVWQEDPEWRMIALHLEKKEHLD"
     gene            76501..77481
                     /locus_tag="VYP66_000398"
     CDS             76501..77481
                     /locus_tag="VYP66_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEV1850008.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTPPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT        23297 a        14569 c        17510 g        22485 t
ORIGIN      
        1 taaaataaga aaattgttta tatattgtct ccgtagtgtt attatacgaa ataaaagatt
       61 ttaggaaaag tcgttatatc atgctatacc tattctttgt ggtataattg caagaggttt
      121 aatccgataa tttataaaga gagaaagata ttcatgagag atttattatc taaaaaaagt
      181 cataggcaat tagaattatt agaattatta tttgaacata aacgttggtt tcatcgttct
      241 gaactagcag agttattaaa ttgtacagaa cgtgcagtca aagatgatct atcccatgtt
      301 aaatctgctt ttcctgactt gatttttcat tcttctacta atggtatacg cattattaat
      361 accgatgata gtgatattga aatggtttac catcatttct ttaaacattc aactcatttt
      421 tcgattttag aattcatctt ctttaatgaa ggttgtcaag ctgagagtat ttgtaaagaa
      481 ttttatatca gttcatcttc gctctatcgt attattagcc aaatcaataa agtgattaaa
      541 aggcaatttc aatttgaagt cagtctgacc cctgttcaaa tcattggaaa tgagagagac
      601 attcgttact tttttgcaca atatttttca gaaaaatatt atttcctaga atggccattt
      661 gaaaattttt catcagagcc actatctcaa ttgttagaat tggtttataa ggaaacaagc
      721 tttccaatga atttgtcaac gcatagaatg ctaaagttgc tcctagttac gaacctatat
      781 agaataaagt ttggtcattt tatggaagta gataaagatt cttttaacga ccaaagtttg
      841 gattttttaa tgcaggcaga aggaatagaa ggtgttgctc agagttttga atcagaacac
      901 aatatctctt tagatgaaga agttgtttgc caattatttg tgtcttactt tcaaaaaatg
      961 tttttcatag atgaaagtct ctttatgaaa tgcgtaaaaa aggatagtta tgttgaaaaa
     1021 tcttaccatc tattgagtga ttttattgat cagatttcag tcaagtatca gattgaaatg
     1081 gagaataagg ataatctgat ttggcatctg cataataccg cacatctgta tcgtcaagag
     1141 ttgtttactg agtttatttt atttgatcaa aaagggaata caatcaggaa ctttcaaaat
     1201 atttttccaa aatttgtttc agatataaaa aaagagcttt ctcactattt agagactctt
     1261 gaggtttgtt ctagttcaat gatggtaaat catctatctt ataccttcat cactcatacc
     1321 aaacatttgg tgattaattt gctacaaaat cagcctaaac taaaggtttt ggttatgagt
     1381 aattttgatc agtatcatgc aaaattcgtt gcagagacac tttcttatta ctgtagcaat
     1441 aattttgaac tggaggtttg gaccgaatta gaattatcaa aggaatcttt agaagattca
     1501 ccttatgata ttattatttc caattttatt attcctccta ttgaaaataa gagactcatc
     1561 tattcaaata atataaacac ggtctcactc atatacttgt taaatgccat gatgtttatt
     1621 cgattagatg agtaaccaaa aataacaaaa aaacgctatt tcgcgtttga actgtacctc
     1681 aaaagttaga cagaaaaagt ctaattttta gggtgttttt gttaagaaaa gaccttcaat
     1741 catttaagaa aaatgtacat ctagatttat agccctctaa aactcttgct ttttttgtag
     1801 aagatacgaa aaaagccatg aaaccaaggc ttttcctgtt ttatgtagat gtttacacat
     1861 gaaaattgaa gtattttcaa aagctaattg gagtgatttt attcatgatg ggataaatga
     1921 tctggccaaa aatgattgag aaatagttgc ttaaaaagca tttgcatgat actatatatt
     1981 gaaaggaggt gataatatgg tagaacaaag aaaatcaatt accatgaaag atgttgcttt
     2041 agaagcagga gttagtgttg gaactgtttc acgtgtaatt aataaagaaa aaggcattaa
     2101 agaagtaact ttgaaaaaag tggaacaagc gattaaaact ttgaattaca ttccagatta
     2161 ctacgctaga ggaatgaaaa aaaatcgaac agaaacgatt gcaatcattg taccaagtat
     2221 ctggcatccc ttcttttcag aatttgctat gcatgtggaa aatgaagtct ataagagaaa
     2281 taacaaatta ctcttatgtt ctatcaatgg tacaaataga gagcaagact atctggagat
     2341 gttgcgtcat aataaagttg atggagtggt tgccattacc tatagtccaa ttgaacatta
     2401 cttgacgtca ggaattccct ttgttagtat tgaccgcaca tactcagata ttgccattcc
     2461 ttgtgtttca tcagataatg atgcaggtgg aagagaagca gctaaacaat taattagtaa
     2521 aggatgtcag catttagcct ttgtgggcgg acataataca accattaatg aaaccaaacg
     2581 tcgtagaatt tcatttgaaa agtatgtcca agagcataaa atacctctta gtatttttga
     2641 tttggatgag acagttactg actattatgg aaagctagag agtttcttgg aagaaaattc
     2701 ttctatagat ggaattttta caatcaacga ttttacagct ttggatgtga ttgaaatact
     2761 agaaaaaaat ggcaaacgta ttcctcatga tgtccaaatt attggatacg atggaattaa
     2821 aatggctgga gatagagatt atctactttc aactattgaa caaccattgg aagaaatggc
     2881 aaaagaagcg gttcgtattt tgtttgatat aattgatgga aagactgtta atttgcagac
     2941 aatcctacca gtaaaatttg ttgaaggaaa aacaacaaaa aatgaaaata agtcttgaca
     3001 gaaagcgcta tcaatgatag aatgaattca gataaaaaga tttattttta aaacaaaaat
     3061 gaaacgtttc aaaaaaagaa ataaagagac agcgccaagc gctatctttt ctagaaaaaa
     3121 tgaaacgttt caaaaaggaa gttgctatga atagcaaagc gaagcaagtt tctctttggg
     3181 aaagaatcaa gaaacaaaaa ctcttgttat tgatgactgt ccctggttta gttttaacct
     3241 ttatctttaa atacatccct atgtatgggg ttttaattgc atttaaagat tacaatcctt
     3301 taaaaggaat tttagggagt gattggattg gtttttctga gtttacaaaa ttcatatcct
     3361 ctcccaactt tggtatcttg ttagccaaca cattaaaatt aagtatctat ggtttattgc
     3421 ttggcttttt accaccaatc attcttgcta ttatgctcaa tcaactcttg agtgaaaaag
     3481 tcaaaaaacg aattcagctc attttatacg caccaaactt tatctcagtc gttgttattg
     3541 tcggtatgat tttcctcttc ttttcagtgg gaggaccaat caacaatttt ctttctatgt
     3601 ttggaatgaa ggctgacttc ttgacaaatc cagacttctt tagaccttta tacatcttta
     3661 gtggtatctg gcaaggaatg ggctgggctt caacgctcta cacggcaaca ttggtaaatg
     3721 tagatccagc cttagtagaa gcagcccgac tggatggagc caatatcttc caacgaatct
     3781 ggcacattga tattccagct cttaagccta ttatggttat ccaatttgtt ttagctgcag
     3841 gtggaattat gaatgtcgga tatgaaaaag cattcttgat gcagacatcg ttaaatttgc
     3901 caacttctga aattatctcg acatatgact ataaagttgg tcttgtatca ggagactatt
     3961 cttactcaac agcggttggt ttgtttaatg cagtgattaa cgtagtattg cttgttgcag
     4021 ttaaccaaat cgttaaacgc atgaataatg gtgaaggaat ttaaggagga aagtatgaaa
     4081 aattcgatta tggatacaaa atttgataga cgtatcttac tcttaaataa aatcattatt
     4141 gtctttatcg ttttgatgac tttgcttcct ttactttata tcgtcgtagc atcctttatg
     4201 gatcctaagg ttctggttag tagagggatt agctttaatc cagccgattg gactgtagaa
     4261 ggttaccagc gtgtattcag tgaccaatct attctaagag gttttatcaa ttctctacta
     4321 tactcttttg gatttgcagc tttaacagtc ttgctatctg tgtttacagc ttatcctctt
     4381 tccaaaaaag atttggtagg gcgccgttgg attaactact tcttgattgt gactatgttc
     4441 tttggtggtg gtttagtccc aacttacttg ctcgtaaaag aattgggaat gctcaatact
     4501 ccatgggcta tcattgttcc aggtgctgtc aacgtttgga atattattct tgctagggcc
     4561 tatttccaag gattgcctga agaattagtt gaagctgctg tcattgatgg tgcaaatgat
     4621 ttacagattt tcttcaaaat catgcttcct cttgcaaaac caattatgtt tgttctcttc
     4681 ctttatgctt ttgtaggaca gtggaactca tactttgatg caatgattta tatcaaggat
     4741 ccaaacttgg aaccattgca acttgtactt cgtaaaattc tcattcagag ccaaccaggt
     4801 caagacatga ttggagcaca agcggctatg aatgaaatga aacgtttagc tgaattgatt
     4861 aaatacgcaa ctattgtcat ttccagcttg ccattgattg ttatgtatcc attcttccaa
     4921 aaatactttg ataaaggaat tatggctggt tcacttaaag gataaaaaaa gaaaaaataa
     4981 aaggagtttt ctcatgaaat tcaaaacatt ctcaaaatca gcagttttgt tgacagctag
     5041 tttagcagta cttgcagcct gtggctcaaa aaatacagct tcaagtccag attataagtt
     5101 ggaaggtgta acattcccgc ttcaagaaaa gaaaacattg aagtttatga cagccagttc
     5161 accgttatct cctaaagacc caaatgaaaa gttaattttg caacgtttgg agaaggaaac
     5221 tggcgttcat attgactgga ccaactacca atccgacttt gcagaaaaac gtaacttgga
     5281 tatttctagt ggtgatttac cagatgctat ccacaacgac ggagcttcag atgtggactt
     5341 gatgaactgg gctaaaaaag gtgttattat tccagttgaa gatttgattg ataaatacat
     5401 gccaaatctt aagaaaattt tggatgagaa accagagtac aaggccttga tgacagcacc
     5461 tgatgggcac atttactcat tcccatggat tgaagagctt ggagatggta aagagtctat
     5521 tcacagcgtc aacgatatgg cttggattaa caaagattgg cttaagaaac ttggtcttga
     5581 aatgccaaaa gctactgatg atttgattaa agtcctagaa gctttcaaaa acggggatcc
     5641 aaatggaaat ggagaggctg atgaaattcc attttcattt attagtggta acggaaacga
     5701 agattttaaa ttcctatttg ctgcatttgg tataggggat aacgatgatc atttagtagt
     5761 aggaaatgat ggcaaagttg acttcacagc agataacgat aactataaag aaggtgtcaa
     5821 atttatccgt caattgcaag aaaaaggctt gattgataaa gaagctttcg aacatgattg
     5881 gaatagttac attgctaaag gtcatgatca gaaatttggt gtttacttta catgggataa
     5941 gaataatgtt actggaagta acgaaagtta tgatgtttta ccagtacttg ctggaccaag
     6001 tggtcaaaaa cacgtagctc gtacaaacgg tatgggattt gcacgtgaca agatggttat
     6061 taccagtgta aacaaaaacc tagaattgac agctaaatgg attgatgcac aatacgctcc
     6121 actccaatct gtgcaaaata actggggaac ttacggagat gacaaacaac aaaacatctt
     6181 tgaattggat caagcgtcaa atagtctaaa acacttacca ctaaacggaa ctgcaccagc
     6241 agaacttcgt caaaagactg aagtaggagg accactagct atcctagatt catactatgg
     6301 taaagtaaca accatacctg atgatgccaa atggcgtttg gatcttatca aagaatatta
     6361 tgttccttac atgagcaatg acaataacta tccaagagtc tttatgacac aggaagattt
     6421 ggacaaaatt gcccatatcg aagcagatat gaatgactat atctaccgta aacgtgctga
     6481 atggattgta aatggcaata ttgatactga gtgggatgat tacaagaaag aacttgaaaa
     6541 atacggactt tctaattacc tcgctattaa acaaaaatac tacgaccaat accaagcaaa
     6601 caaaaactag aggttgatta tgggagataa gaaatacaca gtagaaaaag ccaatcgttt
     6661 tatagcagaa aataaacatc tcgttaatac tcaatataag cctgaagaac atttttcagc
     6721 tgagattggt tggatcaatg atccaaatgg atttgtctat tttcgtggag aataccatct
     6781 cttttatcaa ttctatccat atgatagtgt ttggggacct atgcactggg gacatgctaa
     6841 aagtaaggac ttggtgactt gggagcactt gccagtggca cttgctcctg atcaagatta
     6901 tgaccgaaat ggttgtttct caggctctgc cattgtcaag gatgatcgcc tctggctcat
     6961 gtacactggg catatcgaag aaaaaaccgg tgtccgccaa gtgcaaaata tggcattttc
     7021 agatgacggg attcactttg aaaagatttc ccaaaatcca gttgcaactg gatcagactt
     7081 gccagatgag ttgattgctg ctgatttccg tgatccaaaa ctctttgaaa aagatggacg
     7141 ctattactcc gtagtagctg ccaaacacaa ggataatgtg ggctgtatcg ttctactagg
     7201 gtccgataac ctagtagaat ggcagttcga atccatcttt ttaaaagggg gagaacacca
     7261 aggctttatg tgggaatgcc cagattactt cgagttagat gggaaagatt gccttattat
     7321 gtcacccatg cgttatcagc gtgagggaga ctcatatcat aacatcaact catcgctttt
     7381 gttcacgggt aaggtagatt ggagagaaaa acgttttatc ccagaatcag ttcaagaaat
     7441 tgatcatggc caagacttct atgcgcctca aacattgttg gacgatcaaa atcgtcgtat
     7501 cctgattgct tggatgcaga catgggggcg tacccttcca acccatgacc aagaacacaa
     7561 atgggcatgt gctatgactt tacctagaat tctaagattg gaagatggca aactaagaca
     7621 attccctgtt aaaaaaggcc aatatcaaat ccaaatagat aaagattgtc attaccactt
     7681 aggaaatgat acagattatc ttgaatttgg ttatgacagt aatgcgcagc aagtttacat
     7741 tgatcgtagc catcttattc aaaaaattct aggtgaagaa gaacaggaca ctagtcgacg
     7801 gtatgtagat attgaagcta aagaattgga agttgttcta gataaaaatt ccatcgagat
     7861 ttttgtcaat caaggtgaag caagcttgac tgcaacttat tacttaacgg tgccagctga
     7921 gctatcacga attgattaaa aattaagtta tttctcctaa agaaaaagtt ctctttctaa
     7981 aatagtggaa agaggacttt ttgtgttttg ggtatataag cttagtttat ggtatttgta
     8041 aaattggtgt tggattatga tttaagctag ttttctaaag aatttgaaaa aaattttatt
     8101 taagcaaaaa aaccttggtt ccaaggcttt tcctgttgta tgtagatgcc ccctacaggg
     8161 atcgaacctg tgacccacgg attaagagtc cgctgctctg ccagctgagc taaggaggca
     8221 aagaaaaaag ctgtattggt gccgaaactt cacggtttgt attgaacccg cgcaattaag
     8281 caggtgggca actcgctcta actgaagctg tttccgtgtg agacggccta catgctgtta
     8341 gaagactttt gtttccctaa taatacaaaa aatagtcggt caacacttaa gtgtgaagtc
     8401 gtacaccaca gcgtttctat acttatatga taccactttt tcaaaaaaaa tcaagaggaa
     8461 agtgcaattt tttgaaaagg atttcagatt tttcgcaaac gatcgatagc ttcctttctt
     8521 tgagccaaag cccgttcata tttaccagta tcttctgctt ggaaatagtg atgattacga
     8581 attttttctg gcagatagtc ttgcttgatc caatttccag gatagttgtg tggatagaga
     8641 tagtcttggg cattccccag ttccttgctt ccactgtagt gcccatcacg caggtgtcgc
     8701 ggaataggca agtgccctga tgttttgagg tcagcaagtg ccttatccat agctacatag
     8761 gctgagttgg attttggaga aagggccaaa tcaatcacga cattggcaat gagaatgcgg
     8821 gcttctggga acccaatctt ctgggcagca tccagagcag tcacggtatg aatctgggcc
     8881 tcaggattgg ctaagccgat atcttcatag gcgataacag tcaagcgacg agcgagacta
     8941 ggcagatccc cagcctcaat caagcgggca gtatagtgga gactggcatc cacatctgag
     9001 ccacgaatag acttttgcag ggcagataga acatcatagt gaccgtctcc atccttgtcc
     9061 atagtgatgt agcttctctg aagactattt tccatgatgt ctaaggtgat gtggcgaatg
     9121 cccttgtcat tttcggaagt agagagaaca gccaagtcca gtgagttgaa ggcagagcga
     9181 aggtctccgt ttgtagaggt cgcaatgaaa tccagcgcct cctcatctag ttctactgga
     9241 aaatcaaaac cacgctcagg gttacttaga gctatctgca gggcctcttt gacgtcttgg
     9301 ttagacagag gttccaactc aaaaatttga acacggctac gaatggcagg agtgacagaa
     9361 aagaaaggat tttcagtcgt agcgccaatc atgatgacca gaccactttc caagagaggc
     9421 aagaggaagt cttgcttggt tttatctagt ctatgaatct cgtctagtaa taggacgaga
     9481 ccaccagaga atttagcctc ttccgcaatt tcttgcaatc gctttttact atcaactgtc
     9541 gcattgaaag ttcgaaaggc atactttgtt gttccagcga tggcagaggc aatactggtc
     9601 ttgccgattc ctggaggtcc atagagaatc atggaggaca ggcgattggc ttccaccatg
     9661 cggcggatga tttttccagg tccgaccaga tgttcctgac cgatgacctg gtcgatggtt
     9721 ttagggcgca tgcgaagcgc gagattgtct ggcatagcag tcctttctaa cgtggatttg
     9781 agtagaatga ctcatctact atatcttact atgtccattc tagcctatta gttgtgatat
     9841 ttcaatggtt ttgtaataat cagggagtga gatagaatct tttttactat ttaatttaat
     9901 gaggagaggt atcagcatga gagatttgat tttccttaaa gctcaaaata ggatagttga
     9961 gcctaaagaa gtggaagtgc tgacttgaga aataatattg ctgaatgtca ttgtatgaac
    10021 tataatgaaa agagaggtga taagcaatgg aaatgatgga actaccaagt caggaaattt
    10081 tgatttttac aaaacaaatt cgtcattgga ttcttagtga tcaagttatt tcagggaaaa
    10141 gaaaactttt cttccgggaa gatactccaa aagagatttt agatttgtac gaaaacatta
    10201 aatctaaact tgattttgct taccaagaag ttcattctaa taatgggttg aaaaaatatg
    10261 aaaaatagaa taattgatgt ttttgaagta gtaaatcgcc tccttgtaat aactgttgaa
    10321 aatcctgatt tcgaagactt gagagttaat catactcaat gaaaatcaaa gagcaaacta
    10381 ggaaactagc cgcaggctgt acttgagtac ggtaaggcga cgttgacgtg gtttgaattt
    10441 gattttcgaa gagtatcagt ttgtaaaaat tggagataaa aaatatagag tacgcagtgt
    10501 tcctatgatt cattcaactc cgcctcaatc tgtcttagat cgagatactt ttacaattga
    10561 ctatacagat gatgaattgc tcgataaaga agcagttttt actactcatt agaaaaatag
    10621 gtatgaataa attggcttcc cttagaacca catctagggg cttttatgta taatagaata
    10681 ataagtatca ctcctttaca atacgtgtaa cacgtgttat aatggtgttg tcaggaggta
    10741 aaagcgctat gcctatgaca caaaaagaga tggttaaact ccttacggcc catggttgga
    10801 taaagactag aggcggtaaa ggctcccata ttaaaatgga aaagcaaggg gaaagaccta
    10861 tcacaatcct tcatggtgag ctgaataagt acactgaaag agggataaga aagcaagctg
    10921 ggttgtaaaa ttcagcccct gctttttgat atggaggtag tgaaatgtta gttacgtatc
    10981 cagctttatt ttattatgac gacacagacg gaacagaagc gacttatttt gtccatttcc
    11041 cagattttga atactcagct acacaaggag aggggatttc tgaggctttg gctatggggt
    11101 cggagtggct agggataact gttgcagatt tgatagagag tgatggagag ttacctcagc
    11161 catcagatat caatagcttg tctttaattg ataatgatcc ttttaaagat gatgaagatt
    11221 tcgtgtcaac ctatgacctt gataaatctt ttatttctat ggtatctgtt gatgtatcag
    11281 aatacctagg aagtcaggaa cccattaaaa agactttgac catatcaaaa tgggcagata
    11341 agttgggacg agaaatgggg cttaactttt ctcagacttt gacagacgct attgcagata
    11401 agaaagttca agcctaagat taagcgtggt atcgtggtaa tagtcaataa aaaagcacgt
    11461 ccacttgtgc tagttactcg cctattgatt ttatagattt attagccctt tcgagggctt
    11521 tttatattga tttttatgag aaatgaagaa atcagacttt taagaaaatc actgatacca
    11581 agggtttaaa tgaggtaata tggtataatt aggacataaa ataattttgt ggtaagatgg
    11641 tagtatctat tttagcatat ttccgagcaa tcggggcgat taaagagtcg catagaaaga
    11701 ggacaaaatg gcaacatacg gatttttaga tattttagag gaagagttgg acaagaactt
    11761 tccctttgac tttgagatta gctgggacaa acgcaaccat gcggtagaag tgagttttct
    11821 attggaagcg caaaatgctg caggtgtgga gatggtggat gaagacggag aggtttcatc
    11881 agatgacatt ctttttgagg aagcggtcct tttctacaat cctgccaagt caacagtcaa
    11941 tgaggaagac tatttgactg ttattcctta cctgcctaaa aaaggatttt cccgtgaatt
    12001 tttagcttat tttgcgcttt tccttaaaga tactgctgag gttgggctag atgtcctcat
    12061 ggactttttg gaagacccag aagcagagga atttgtcatg gaatggaacc aagaagtctt
    12121 tgaagaagga aaaattggct tggaaaaggg agaattttat ccttatccaa aatactagga
    12181 gttggttgga ggtgttatga agaaaattgg gacttatttg gtttatgtgc tagctgttgt
    12241 ctttattatg ctagcttttg cttgtggaac aatcgcattt gcagagttgg ggtattccgc
    12301 agttttagcc tttacttttg gttatgcctt cgctcttcta agcatgtatt taatctttat
    12361 tcttcatgag ctgggtcatg ctttttgtgg ctacttgaca ggctatcggc tggtggcttt
    12421 tggattagga cattttattt tgaccaaaaa gtcaggcagg tttcatctta gtagaacagc
    12481 cattctgaaa aatgttggtg ctcaatacat tggtttaaaa gaggatgaaa gcgatcaaag
    12541 aatcatcctg atgctttcag gaggcttgat ggttcatctc ggcttgatat tattggcgat
    12601 attgtttgga tttttgacaa gaagctggta ttttgcaggg acttggattt ttcttaattt
    12661 atctttcttc ctaaataaca ttttgccagt cgacatcacc gatggagcaa aaatttggga
    12721 attactacaa caccctgaaa ataccaaata cgcctacctg gtattgagac attctgccca
    12781 gaccttgcta gctcctcaag aatatgattt gaaagacttt gttcaagcag ttcctgagga
    12841 tgcacgaggg agttttgcgg atggtgtatt aggtatgcaa ggtgaagttt ccattttgga
    12901 agggaaggaa gaagtagcta aacagcagtt tcaagcatta cttgagagga caactactcc
    12961 gatgatgcag acagttgccc aactatccct gcttcatatc gccttgttgg aaggagattt
    13021 tgagcaagcg gagcaatatg ctagtattcg acaggtcaaa tcgtttctgt ctctcaaact
    13081 gtccaatctt caagtgatac aagcctggta tcaattaaag gtgaagaaag atgtagatcg
    13141 aactcgtaag gctctcaaga ttgctagaca gaaaatggat agtagtcgaa tgttgaggga
    13201 tgagaaaaga tattatgaaa actggttagc cgagctggaa aaggaaatgt tagaaggaac
    13261 tgaagatgga actagaaatt tctgatttca caggttgcaa aattgctttg ttttgtgggg
    13321 ataagctttt gactatctta cgcgatgata aggcaagtat tccctgggcc aatatgtggg
    13381 aactgccagg tggtggacgt gaaggtgatg aaagtccttt tgagtgtgta gcgcgtgaag
    13441 tttatgaaga actgggcatt catctgactg aagattgtct gctttggagt aaggtttacc
    13501 caagtatgct ttttgcagac aaacagtccg tttttctagt tggtcagttg acacagaacc
    13561 agtttgacag tatcgtattt ggagatgaag gacagggcta tcagctgatg aatgttgagg
    13621 aatttcttag ttccagtcaa gttgtgcctc agttgcaaga gagattaaaa gattatttaa
    13681 aagtaagtga ttagaaagga tggttcggtt aaatttctaa actgaacccg ccctaaacac
    13741 ggtgccaaaa agataaactt ctcttagaca caagcgtctt cagagaattt cctattttgg
    13801 ttttgtgttt tacgggcttg gtattaataa tggaaacatg gcaagagtta aaagttacag
    13861 tgaagcgtga gggagaggag ttggtttcca atctcttgat tgagctggga gcgcaaggag
    13921 tcgcaatcga agacagtatg gactatgtgg gaaatgtgga ccgctttgga gagattttcc
    13981 cagaggtgga gcagcaagaa gaaatcgtag tgacagccta ctaccctgac acggtggatg
    14041 tgacagtggt tgaggcggat ttgcaggctc gtctagcaga attgacagat tttatggatt
    14101 tgggagagtt aaaaataggt acgactgcct tggctgagga agactgggca gacaactgga
    14161 agaaatacta tgaacctgct cgcatcactc atgatttgac catcgttccc tcttggacag
    14221 actatgaggc gactgcggga gaaaaaatta tcaagctgga tcctggcatg gcttttggta
    14281 cgggaaccca cccaactacc aagatgagcc tttttgcctt ggaacaggtt cttcgtggtg
    14341 gcgaaacggt gctagatgtg ggaactggtt caggggttct ctctattgcc agctcgcttc
    14401 tgggggctaa agaaattttc gcctatgacc tggatgatgt ggcagttcgt gtggctcagg
    14461 aaaatattga gctcaaccct ggaatggaaa atatccatgt agcggcaggc gatttgctta
    14521 aaggcgtgga gattgaagca gatgtcatcg tggcaaacat cttggcggat atcctcattc
    14581 atctgacaga ggatgcttat cgcttggtta aggatgaagg ttacctgatc atgagtggca
    14641 ttatcaagga taagtgggac atggtgcgcg agttggctga atcagctgga tttttcctcg
    14701 aaactcacat ggttcaaggg gaatggaatg cctgtgtctt taagaaaacc aaggatatct
    14761 ctggtgtgat tggaggctag catgcagcag tattttgtaa aaggcagtgc tatctctcct
    14821 gtcactatcg agaacaagga aaccagtaag catatgtttc aggttatgcg cttgaaagaa
    14881 gaggatgagg ttaccttagt ctttgatgat ggcatcaagc gcttggcgcg cgtgctggat
    14941 atggaaaatc gtcagtttga gttggtccaa gaattaaatg acaatgtgga actaccagtc
    15001 caagtgacca tcgcatctgg atttcccaag ggagacaagc tggagttcat cgctcaaaaa
    15061 gtaaccgaac tgggtgctag ccaaatctgg gcctttcctg cagactggtc agttgccaag
    15121 tgggatggca agaaattggg taaaaaagtt gaaaaactag aaaaaattgc ccttggagca
    15181 gccgagcaaa gcaagcgtaa tattgtacca agtattaaac ttttcgagaa aaaagcagat
    15241 tttctagctc agctggacca gtttgacttt atcatagtag cctatgaaga atcagctaaa
    15301 gaaggagaag ccgctgcgct tctgcaagca gtcactggtc ttgaaacagg agccaaactg
    15361 ctctttatct ttggtccaga aggcggtctc tcacctgcag aaatcgaaag ttttgaagct
    15421 aagggagccg ttttggtagg cctaggtcct cgtattttgc gagcagaaac agcaccgctt
    15481 tacgccttat cagcccttag tgttttagta gaattagaga aataagagga agaaaatgga
    15541 acaaaaacac cgttcagaat ttccagagaa ggaactctgg gacttaacag ccctatacca
    15601 agaccgtgag gatttcttgc gtgcaatcga gaaagctcgt gaagacatca accagtttag
    15661 ccgtgattac aagggcaatc ttcacacttt tgaggatttc gagaaggcct ttgcggaatt
    15721 agaacagatc tacattcaga tgagccatat tggcaactat gcttttatgc ctcagacgac
    15781 ggactatagc aatgacgaat ttgccaatat tgcccaagct gggatggaat ttgaaacaga
    15841 tgccagcgta gccttgacct tctttgacga tgccttggtg gtagcagacg aggaagtctt
    15901 ggaccgtttg ggtgaattgc ctcacttgac ggcagctatt cgtcaggcca aaatcaaaaa
    15961 agcccactat ctaggggctg atgtggagaa ggccttgacc aatctcggtg aagttttcta
    16021 tagtccgcag gacatttata ctaagatgcg agctggggat tttgaaatgg ctgactttga
    16081 agcccatggc aagacctata aaaacagctt tgtcacctat gagaatttct accaaaatca
    16141 cgaggatgct gaggttcgtg agaaatcctt ccgttccttc tcagagggac ttcgtaagca
    16201 ccaaaatacg gctgcagcag cctatctggc tcaggtcaag tctgaaaaac tcttggctga
    16261 tatgaaggga tacgactctg tatttgatta tcttctagct gaacaagaag tggaccgtgt
    16321 catgtttgac cgccagattg acctcatcat gaaggacttt gcaccagtcg ctcagagata
    16381 cctcaagcat gttgccaagg taaatggtct tgaaaagatg acctttgcag actggaaatt
    16441 ggacttggac agcgccctga atcctgaagt gactattgac gatgcctatg atttggtcat
    16501 gaagtcggta gaacctttgg ggcaagaata ttgtcaggaa gttgctcgtt accaagaaga
    16561 gcgctgggtg gactttgctg ctaacagtgg caaggattcc ggtggttatg cggcggaccc
    16621 atatcgcgta cacccttatg tactcatgag ctggacaggc cgtttgagcg atgtctatac
    16681 cttgattcat gaaatcgggc attctggtca attcatcttt tcagacaatc accaaagcta
    16741 tttcaacgcc cacatgtcga cctattatgt tgaagcaccg tcaaccttca atgaattgct
    16801 actcagtgat tacttagaga accagtctaa tgacccacgt caaaaacgct tcgctctggc
    16861 tcatcgcttg acagacacct acttccataa tttcatcacc cacctcttgg aagccgcctt
    16921 ccagcgtaag gtgtatacat tgattgaaga aggggagacc tttggagcaa gcaagctcaa
    16981 cagcattatg aaggaagttt tgacagattt ttggggcgat gccattgaaa tcgacgacga
    17041 tgcagctttg acttggatgc gccaagctca ctactatatg ggcttgtata gttacactta
    17101 ctctgctggt cttgtcatct cgacagctgg ttaccttcat cttaaaaact cagaaactgg
    17161 agctgaagac tggctcaatc tcctcaaatc aggtggtagc aagacaccac ttgagtcagc
    17221 catgattatc ggtgctgata tttcaacaga caaaccactc cgtgatacca tccaattctt
    17281 gtctgacaca gttgaccaga ttatcgccta cagtgctgag ttgggggagt aaggggaata
    17341 gaaaaatttt ctagaatgat gtttatgggc ttgttaagcg tcattctatt tgtcttagtt
    17401 gtagctattt tcaaaaatgt cgttgaaggt cgtgatgtta aatttgaact tactgtagaa
    17461 ctggtattga tagttattta cgtcatttta tatcagattg tatttaattg agaattcaat
    17521 attgagtcat ttaagactgc ctttttgaac agttgctaga aatgtagagg tattgaccat
    17581 gtatcaagat ttactaagaa aaatagcaga agaaaaacca aattataacc aggaagaaat
    17641 ccagtggttg tttgatcatt tgggaaatcc ttctccagaa attcgtgatg acctttcaaa
    17701 tcaaggcttg cactatcttt caaaagaaaa ggatacaaca gatttctcaa gtcagtatgg
    17761 ttgggttcat gcttttgcac atggagccga tttactgaca gaggtggttt gtcatccaga
    17821 ctttcctata aacagaattc atgaagtatt tgacatactt ggccaactat ttaaaagaat
    17881 gtcgattcgc tttacagatg atgaggattg gcgtttagca agagtgatct atgaacctat
    17941 tttacaaggg aagttggagc aagaacaagt agcttcttgg ataaaaactg ttgattttcc
    18001 gatagaagaa agggaggatt tttacaaatt ttccaacttt agatcctgtc tggtggaagt
    18061 ctatgtccaa cttgaccaga gaaatagttt acaagatgac ctgaaagaag ctatccagtc
    18121 ttttcaatac tagagattag ctaatagttc tatgattttc aaaaaatttc caatcaattt
    18181 tcttgaaacc ctttcctact tttgatagac tagtatctag tttttgaaaa aaggagaaag
    18241 aaaatgaaaa aatttgttgc tgagttaatc ggtacgttca tgcttgtgtt cgttgggaca
    18301 ggagctgttg tttttggaaa tggtcttgat ggccttggtc accttggaat cgcctttgcc
    18361 tttggtttgg caatcgtggt ggcagcctac tcaatcggaa ctgtttcagg tgctcacttg
    18421 aacccggctg tttcgattgc tatgtttgta aacaaacgtt tgtcatcttc agaacttgta
    18481 aactacatcc ttggtcaggt tgttggagct ttcatcgctt ctggcgcagt cttcttcctc
    18541 ttgggtaatt caggtatgtc aactgctagt cttggtgaaa atgccttggc aaacggtgtc
    18601 actgtctttg gtggtttctt gtttgaagtc atcgcaactt tcttgtttgt cttggttatc
    18661 atgactgtga cttcagaaag caagggcaat ggcgcgattg ctggtttggt aatcggtttg
    18721 tcattgatgg cgatgattct tgtcggattg aagattactg gactttcagt aaacccagct
    18781 cgtagcttgg caccagctgt cttggtaggc ggcgcagccc ttcaacaagt ttggattttc
    18841 atccttgcac caatcgctgg tggagttctt gcagcccttg ttgcaaaaaa tttccttgga
    18901 acagaagaat aattgaaact caaaaagcct tgctcctcat cttgaggaac agggcttttt
    18961 cgtatgatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtatg
    19021 gttactgact tcgtcagttc tatctgcaac ctcaaaacag tgttttaagc tgacttcgtc
    19081 agtttcatct acaacttcaa aacactgctt tgagcaacct gcggctaact tcctagtttg
    19141 ctctttgatt ttcattgagt atgagtttag cggttgtcaa ttttctctgg ataaaggtcg
    19201 tgttggaaga ggcgttgttc tgccaagccc tcatacttag ttccttgctt accgtagttg
    19261 tagtaggggt cgattgaaat gccaccgcgc ggagtgaatt ttccccagac ttctaaatag
    19321 cgagggtcta gcaagttgac caagtctttc ccgatggtgt tgatacagtt ttcgtggaaa
    19381 tctccgtgat ttcggtagct aaatagatat agtttgaggg attttgactc gacacagagc
    19441 ttgtcaggaa tgtaggaaat atgaatcgtc gcaaagtctg gttgagcagt gatttgtccc
    19501 agcagagaca tatcgaggat atggtgacga atgccctgtt ccttagcgat ttctctagca
    19561 atttgaattt cgaggtgatg acgttggccg taggcaaagg tgacagcttc gactgtttca
    19621 tagtgttgca tggtccagaa aaggcaggtt gttgaatctt gaccgccact aaagacgacc
    19681 aaggctgatt gacgtttcat agtactcctt ccaaaatggg aaatgttcag agcacgcaaa
    19741 aagctcccat tagggagcta aaaaatacca aatcgaggtt tttttagcga tggcatatcc
    19801 caaacatcgt aatattctac ttatatagta aaatgaaata agaacaggac aaatcgatca
    19861 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
    19921 atatactata gtctagcata ttttttgaaa aatggcaaag ggcaagaaaa aagagaccaa
    19981 agaaagtact tggtctctcg tttgattagc tcaattcagc aatgatggcc ttgatttgtt
    20041 ctgctgtgtg aacacctgca acctgtttga caacttggcc gtcttttttg aagagaagag
    20101 ttggaataga catgattcca aaagcacgag ctgtgtttgg attttcatca acgtccattt
    20161 taacgatttt caagacatct tctgaaagtt cttcagacaa tttgtccaag attggacctt
    20221 gcatacgaca tggaccacac caagttgccc agaagtctac taagaccaaa ccgtcttttg
    20281 tttcttgttc gaatgttgca tctgtaattg cttttgccat tgtatttctc ctttttttag
    20341 ttatattggc ttaaatcttg tttcatgaga tagaagaaga tatctccata agtcccatgg
    20401 tagtccaaat tatgaccctt gtaagttaat ttttggacag ggtagtagtc tgcgacgccg
    20461 ataaggcaag cttgttgcga acgttcaaag tcttcataag actcgaaagt cacagttctt
    20521 tcgttcttgc tggcatctat ataggtaatt tcaatcatat ttaaaactcc tttgtttaat
    20581 gctaacttta ttttactcct tataaaagag aatgtcaaga aaaatgattg cgcacgcaac
    20641 tttttttaaa atcatcttaa atcaagaaat ccaaacctgc ttccaagctt tcttcgacag
    20701 tcttttgtag cgaggccagt gtcttttgcc catcatttgt caggcagata aaactagagc
    20761 gtctatcttg atggcaacac atgcgactga gtagaccgca atttttagct tccaagcgag
    20821 ccaccatcct agaaactgcg ctcgggctca gatgaagctt atctggcagg tcaatctggc
    20881 gtagagattt ttcttcagcc aagtccagat agtagagcag gtagaactct ttcaaggtca
    20941 gactttgctc gctctgttgg gcaatggtct cttccaagag actttcaatt tctttctgac
    21001 gccgattgaa gtcaaaccat ttttccaaat aggtcatagt gtctcctttc tttttagagt
    21061 cataaaatag aagaaagtcc attaacgggc agtctctgcg tcacaagatg attgcgcatg
    21121 caataattat actacttttc aagaatgctg gcaagctctg ttttttagtg gttttatttt
    21181 ttactgtcca tatttttggt aaaaatcaac ttttacttgg atgaaggttt tggcttcacg
    21241 taggagttga agaagggtgg cgcgggtttc aaactcttct cttgtcttgg gcagactgcg
    21301 gttccggaag acttccagat aactttcaat ttcatctagc aaatcagaag caggattggt
    21361 ctggctcagt tgaccagcaa tttttgaaaa gagctgcgct aaaatcaggc tttcactggc
    21421 ggcaaggtga caagtgttaa tctgttgggc catgtttctc aggatacgac tttgtcgttg
    21481 tctcatctca aagtagtgga tatggtagtc ggtctggtga aagaggtggt cagagtgatc
    21541 caaatagacc agtctgaggg cttctttcaa aagcgtgtct aattctgcta ccagctgtgc
    21601 tcggttgcgt ccgtctcctc tggataaata gtatttgaag cgctggagga tatcttttaa
    21661 cttttcttcc accagcgtgt ggtagtgctg gattttcttt tctcgtgaag gcatgtagag
    21721 attgaccagt aaagcaaatc ctgtaccgat agcaaagaga aggaattcat tgactagaag
    21781 gtctggagag gttgactctt gaaccaagag atggctaacc aaaacagtgc ttggtgtgat
    21841 accaatttcc cagcccatct tgtaggctaa aggaacgtag aaggccagat agaggccgag
    21901 actccagata tgaaatccgc tcaaatgaaa agctagaaca ccgatagcca gagctagaag
    21961 catagaaaaa agacgattgc gagccagttt taaagtactt ctacgcgtat cagataggct
    22021 caagagagcg ataattccag ccgaaactgc tgacgaaaga ttgagaaaat aagcaagcag
    22081 gcaggcaaga caggtagcta agatgagctt ggtcgtacgt tggctaatag acataagaat
    22141 ttcctaataa gttagaataa aagcgtaaaa gacaagacat gagcaggctt gccttgatga
    22201 gttatttttt acgggttgct gcgtattcgg caacggcggt aaagaggaca tctgtagaag
    22261 agttaagggc tgtttcacat gagtcttaga tgacaccaat cacaaaacca accccaacaa
    22321 cttgtatggc aatatcgtta gaaataccga aaaggctaca agcaactggg ataagaagga
    22381 gggaacctct ggcaatacct gaagcaccac aggctgagat agctgctacc acactgagga
    22441 caaaggttgt ggcaaagtca acaggaattc caagagtgtt aactgcagca agggtcaaaa
    22501 ggttaatggt aatcgctact ccagccatat tgatagtaga accgagtggg atagaaacag
    22561 aataggtatc tgggttgagt ccaaggtcat ggcagagttt catgttgaca ggaatgttag
    22621 ccgcagaact acgagtgaaa aaggctgtca caccgctgac acggaggcag ttccaaacta
    22681 gagggtaagg attgcgtctc ataaagaaga aggcaatcaa agggtgacca caagggcaac
    22741 aaaaagcata gtcgttacta atagaaccaa taaaataccg tagttggtaa ggcttccgac
    22801 tcccttgtca gaaatggttt taaaaacaag accaaggctt ccaaatggag ccagattgat
    22861 gatccattcg acaattttag aagtcacgtc agcgatagtt tttagcaatt ctttactatt
    22921 tttactggct tctctcatag cgattccaaa aatgactgcc caagataaga ttctaatata
    22981 gttagcagta aacagggcgt tgactgggct gtcaaccagt ttgagcaaga ggttgctgag
    23041 aacctgccca accccatctg gtggtgcaat ttcagtattg gcactattta gggtaatttc
    23101 aatagggacg atgaaacttg ctagtacagc tacaagagca gcggcgaaag tccctatcat
    23161 aggatataca agaaaacaac agttttcata ttgctatctt gtcccttttg atgttggaaa
    23221 gggcattggc aacgagggca aagactagga taggagcaac agcttttaga cctccaacga
    23281 ataaatcccc gagtagccca atccctgaga gattaggaag ggtcagtcct aggattcccc
    23341 acaaagcata ccaatcaaga tacgcttgac aaggcttgcc ttattccaag catgaatgat
    23401 tcttttcata ataatctcct ttttgtgtag tgattatgat tatagtataa atgatagaca
    23461 aaatcaagaa ttttctgtct attttttgaa tatttatgga gaatgagact gatgaaaata
    23521 tggtataatg aaataaagga gttttatatg caaaaattta ttcaggctta tattgaaaag
    23581 ctagatgtga caaccattat cgagaatatt ctaaccaagg tcatttctct tttactgctt
    23641 ttgattgtat tttatattgc taaaaaaatg cttcatacca tggtgcagag aattgtcaaa
    23701 ccttctctaa aaatgtctcg tcatgatgtc ggacgccaaa aaaccatctc acgtttacta
    23761 gaaaatgtgt ttaattatac gctatatttc tttttactct actgcatttt gtcgatttta
    23821 ggtttgccag tttctagttt gctggctgga gctggtattg ctggggtagc gattggtatg
    23881 ggagcccaag gctttctgtc tgatgtcatc aatggctttt tcatcctctt tgaacgtcaa
    23941 ctggatgtgg gagatgaggt cgttctgaca aatggaccga ttactgtatc gggtaaggtt
    24001 gtcagtgtgg gaattcgtac gacacagctt cgtagcgagg agcaagccct tcactttgtc
    24061 cctaaccgaa atatcacagt tgttagcaat ttctcacgca cagactagac ctgttatttt
    24121 aagtaatttg tggtacaata gagggagttt aataaggaga aaagatggtt ttagaaaagc
    24181 agttgggcaa tggttgtacc tggatagacc tagacctagg aaagttgaat aaactagaag
    24241 acctttctga aatttacggt ttggacaagg aaaccattga atacgcactg gatagaaacg
    24301 agcgcgccca catggactac caccgtgaaa gtgggacggt tacctttatc tataatgtcc
    24361 tagacgtaaa aaaggacaag gcctactatg agacttttcc catgaccttt attgtcgagc
    24421 atcgtcgcct gattaccatt agtaatacca agaacgccta tgtcattgaa cagatgactc
    24481 gttatctgga gagccatgac acgctttcga tttataagtt tctctttgcc agtctggaaa
    24541 tcatcagcaa tgcctactat cctgtcattg agcagatgga caagagtagg gatgaggtca
    24601 atgacctctt gcgccagcga actaccaaga aaaacctctt tgccctgtct gatttggaga
    24661 ctggtatggt ttatctaacg gcagctgcca aacaaaatcg gattttgtta gagcatattc
    24721 aaggtcatgc cttgtatcgt agttttgatg agattgagag agaacagttt gatgatgcca
    24781 tgattgaggc tcatcagctg gtatccatga cagacctaat ctctcagatt ttacagcagc
    24841 tttcagcctc ttacaacaat attctaaaca ataatctgaa tgacaatttg acaaccttga
    24901 ctatcatttc agtcttgcta gctgttttgg cagtcgtgac aggctttttc ggaatgaatg
    24961 ttcccttgcc tttaacagat gagccccatg cttggctcta tatcagtttg gctagtgcag
    25021 gtttgtggat tgttttatcc ttgttactaa ggaaaattgc gaaaaaaagt taagaaaagg
    25081 agccagaatg gcgattgaaa attatatacc agattttgct gtggaagcag tctatgatct
    25141 gacagtccca agcctgcagg cgcagggaat caaggctgtt ttggtcgatt tggataatac
    25201 cctcattgct tggaacaacc ctgatggaac gccagagatg aagcaatggc tacatgacct
    25261 tcgggacgcg ggtattggca ttatcgtagt gtcaaataac accaaaaaac gcgttcaacg
    25321 agcagttgag aaatttggga ttgattacgt ttactgggcc ttgaagccct tcacatttgg
    25381 tattgaccgt gctatgaagg aattccacta tgacaaaaag gaagtggtca tggttggtga
    25441 ccagctcatg acagatatac gagcagccca ccgtgcaggg attcggtcaa ttttagtcaa
    25501 acccttggtc caacatgact caatcaaaac gcagattaac cgaactcgtg agcgtcgtgt
    25561 tatgagaaaa atcactgaaa agtacggacc gattacatat aaaaaaggaa tttaactatg
    25621 gaagaaattc tctgtattgg ttgtggagca accattcaga cgacagataa agctggtctt
    25681 ggttttaccc cccagtcggc acttgaaaaa ggtttggaga ctggcgaagt ctattgccaa
    25741 cgctgtttcc gtctccgcca ctacaatgaa atcacagatg tccagttgac gaacgatgat
    25801 ttcctcaagc tcttgcacga ggtgggagac agtaatgcct tagtggtcaa tgtcattgat
    25861 atctttgatt ttaatggatc tgtcatccca ggtttaccac gtttcgtctc tggcaatgat
    25921 gtcctcttgg taggaaataa aaaagatatc cttcctaagt cagttaagtc tggtaagatt
    25981 agccagtggc tcatgaaacg tgcccatgaa gaaggtcttc gtccagtcga tgtggtccta
    26041 acttcagcac aaaataaaca tgccattaag gaagtcattg acaagattga acactaccgt
    26101 aagggccgcg atgtctatgt ggtcggtgtg accaacgttg gaaaatcaac tctaatcaat
    26161 gctattatcc aagaaatcac gggtgatcag aatgtcatca ctacttcacg cttcccaggg
    26221 acaaccttgg acaaaataga gattccgctt gacgacggat cttatattta cgatacgccg
    26281 ggaattatcc accgccacca gatggctcac tacttgacgg ccaaaaacct caagtatgtc
    26341 agtcctaaaa aggaaatcaa gcctaagacc tatcagctta atcctgagca aaccctattt
    26401 ttaggtggtt tgggacgctt tgactttata gcaggagaaa agcaaggatt tactgctttc
    26461 tttgataatg aactcaaact ccatcgtagc aagcttgaag gagctagtgc tttctacgat
    26521 aagcacctgg gaactcttct gacaccacca aatagcaagg aaaaagaaga tttcccaagg
    26581 ctagtccagc atgtctttac cattaaagat aagacagacc tagtcatttc aggcctaggc
    26641 tggattcgtg taacaggcat agcaaaagtc gccgtctggg caccagaagg cgtcgccgtc
    26701 gtcacacgaa aagcaattat ttaagcacag aaaggaaagg gttgtctgaa tttgggcgag
    26761 caaggcgagc cccatagaga atacttttcg ctgtggtgta agttggtaca agtgattgta
    26821 ccaactgcgg aaaatttgag accttaggct caaattttag tcatgaaagt ccgaaggact
    26881 ttgctgacgt ccgtcaccac ttcagaaaag tataaaaaga aactctttta aagaaattat
    26941 gtcattaaca tcaaaacaac gtgccttcct caacagccag gcacacaccc tcaaacctat
    27001 catccaaatc gggaaaaatg gactcaacga ccaaatcaaa accagcgtcc gtcaagctct
    27061 tgatgcgcgt gaattaatca aggttactct cttacaaaac acagatgaaa acatccacga
    27121 agtagctgaa attttggaag aagaaatcgg tgtggataca gtccaaaaaa taggacgcat
    27181 cttgattttg tttaaacaat ctagcaagaa agaaaatcgc aagatttcta agaaagtcaa
    27241 agaaatctaa gaccgaaact ccaaataact gtttttatag agaaataaag gggactagcc
    27301 tatgacaatc gaactattga ctccctttac caaggtagag ttggagccag aaatcaagga
    27361 gaaaaaacgc aaacaagttg ggattttagg ggggaatttt aaccctgttc acaatgccca
    27421 tctcattgtt gcggatcaag tacggcaaca gttgggactg gatcaagttc ttctcatgcc
    27481 tgaataccaa cctcctcacg ttgataaaaa ggaaaccatc cctgaacacc atcgtctcaa
    27541 gatgcttgag ttggcaattg agggaattga cggcctagtc attgaaacca ttgagttgga
    27601 gcgcaagggt atttcctaca cctacgacac catgaagatt ttgacagaga agaatccaga
    27661 tacggattat tactttatca tcggtgccga catggttgac tatctgccta agtggtaccg
    27721 aattgatgaa ctggttgaca tggttcagtt tgtgggggtt cagcgtccac gctacaaggc
    27781 agggacttcc tatccagtta tctgggtgga cgtaccgctc atggatatct cgtccagcat
    27841 ggtgcgggac ttcattgccc aaggtcggaa acccaacttt ctcctacctc agccagtgct
    27901 agactacatc gagaaggagg ggctctactg atgtcctatc aagactatat caactgctcc
    27961 cgtgaggcct tgttggaaaa aatggcagag cttctacctg agaaacgtct aacccattgt
    28021 ctaggtgtgg agcgtgccgc tatggaatta gctcagcgct ttggtgtaga tgttgagaaa
    28081 gcaagtctag caggtcttct tcatgactat gctaaaaagt tgtcagatca ggaatttcta
    28141 gacttgattg accgttatca gctagatttc gacctcaaaa actggggtaa taatgtctgg
    28201 catggtatgg tcggaattta caaaattcag gaagatttgg atttgcatga ttctgaaatt
    28261 ctgcgagcca ttgaaattca tacagtcgga gctggtcaaa tgacagacct agataaggtc
    28321 atctacgtcg cagactatat cgagcacaat cgggcatttc ctggagtgga tgtggcgcgt
    28381 gagattgcaa gtctatcgct caataaggcg gtggcctacg aaacagctcg taccgtggag
    28441 tatctagctc atcagggatt ccccatctat ccccaaaccc ttgaaaccta taacgccttt
    28501 gtgcactatt tgaaagagga ctaaatgaag acggctttta taatcattga tgttcagaat
    28561 gttttagtag aaactgggtt ccagacaaaa agtctattgg aaaaaatttc ttatttacaa
    28621 aaccaggcta gaagcaagaa tattgaaatt atctatgttc aacatattga gaactctgaa
    28681 gctcaaacat cagaagattg gcagttatct gcgcttttaa atcgaaaacc tgctgaaaag
    28741 gtctttcaga agaagtataa cagtattttc aaagaaactg gcttaaaaga atacttggat
    28801 aagcagggga ttgaaaaatt agttttatgt ggtatgcaga cagaatattg tgtggatacc
    28861 tctgtcaagg ttgcctttga atatggctat cagcttattg ttccagaagg tgctgtcaca
    28921 acctttgatg gggatgacat tccagcagaa acgattaatg aattttatga ggacatttgg
    28981 gaggagcgct ttgcagatgt tctagattac aaacatattt tctaaaaaga ggattaaatg
    29041 aacgaaaaag aattactaga actagtcgtg aaagcggctg atgagaaacg tgcggaggat
    29101 atcctcgcac ttgatgtaca agatttgact agtgtgacgg actactttgt catcactagc
    29161 tcaatgaata gccgtcagtt ggacgctatc gcagctaata tccgtgaaaa agtagctcaa
    29221 gcaggcttta aaggtagcca tgtcgaaggc gatgcagctg gaggctgggt cttactggac
    29281 ctcggtgctg ttgtcgtgca tatcttttca gaagaaatgc gtgcccatta taatctagag
    29341 aagctatggc atgaggcgaa ttcagtagat atttcagaag ctcttgctta gaagatgaac
    29401 tcagttgtag tcaactgggt ttctttgctt attttagaaa aattgataga aaggtaaagg
    29461 gctagtggtg tttaccatgg agctcttagt atcatgatta tggcgactta tgaaaccttt
    29521 gcggcggtct atgatgcggt catggacgat agtttatacg acaaatggac gaatttttct
    29581 ctgcgtcatt tgcctaagac caaggagaga aagaaactct tggaattggc ttgtgggaca
    29641 ggaattcaat cagtgcgctt ctctcaggct ggttttgatg tgactggact tgacttgagt
    29701 gcggatatgt tgaagattgc ggagaagaga gcaacttcag ccaagcaaaa gattgctttt
    29761 atagaaggta atatgctgaa tttgtccaag gcagggaaat acgattttgt cacgtgttat
    29821 tcggactcta tctgctatat gcaggatgag gtggaagtag gggacgtctt taaggacgtg
    29881 tacaatgcgc tgaatgaaga gggagttttc atctttgacg tgcactcgac ctaccagaca
    29941 gatgaagtat tccctggcta ttcctaccat gaaaatgcgg aagattttgc catgctttgg
    30001 gatacatatg aggacgaagc tcctcactcc atcgtgcatg agctgacttt ctttatcaag
    30061 gaggctgacg gttcctttag tcgccacgat gaagtacatg aggagaggac ttatgagatc
    30121 ttgacctatg atatcttgct ggaacaggct ggattcaagt ccttcaaact ctatgcagac
    30181 tttgaggata aggaaccaac agaaactagc acccgttggt tttttgtggc gcagaagtag
    30241 gagaacatca tgaccatcac aggtattatc gcagagttca atccttttca taatggccat
    30301 aaatacctgc tggatcaggc agagggactg aaaattgttg ccatgtcagg gaatttcatg
    30361 cagcgtggag agcctgctat tgtggataag tggacaaggg cccagatggc gctggaaaat
    30421 ggcgcagact tggtagtgga attgcccttt ttagtcagtg ttcaggcagc tgatttcttt
    30481 ggtcaaggag ctgtggatat cttggatcgc ttgggcattg atagtctagt ttttgggaca
    30541 gaggaagttc gagattatca gaaaatcgct gacttataca cagagaaagg tgctgagatg
    30601 gagaaatttg tggaaaatct gcctgattcc ctttcctatc cccagaaaac ccaatctatg
    30661 tggaaggaat ttgctggtct tgatttttca ggtaataccc ccaatcatgt tcttgctctg
    30721 gcctatgcaa aggcggttgc aggacgaaat atcaagctgc atacgattca gcgtcagggg
    30781 gcaggttacc attctgtgaa taaagatgtg gactttgcct cggcgacagc cctccgtcaa
    30841 catcagaagg accaagattt cttagaacgc tttatgcctt ctgttgccct atttgagcag
    30901 gccagtaagg tgatctggga agactatttt cccttgctcc gctatcaaat cttgtcaaat
    30961 cccgacctaa ccaccatcta tcaggtcaat caagaaatgg ctgtgcgcat taaagaagct
    31021 attaaaacag cccagtctgt agaagagttg gtcgaggcgg ttgcgaccaa acgttacacc
    31081 aaggcgcgtg tcagacgcct attgacctat attttggtgc aggctagaga aaatgtcttg
    31141 ccagaagcca ttcatgtcct tggatttact gaaaaaggca ggcaacatct caagtctctg
    31201 aaaggacagg tcaatctagt cagccgaatt ggcaaagaac cttgggatgc tatgacccaa
    31261 aaagcagacc agatttacca actaggaaag ccaagtatag cagagcaaaa ttttggaaga
    31321 gtgccgatta gaatagaaac aagctaagtc taccgaaagg taggcttttt gagatttttt
    31381 acgaataata ctcttcgaaa atcaaattca aatcgcgtca acgtcgcctt gccgtactca
    31441 agtacagcct gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaatagat
    31501 agaaaagaaa atcttgtaca agttcctgac aatttctttc ttttcgtgta taatagtgga
    31561 aaagagctaa aacgaggtat ggttatggaa gcagtccttt actcaacatt ccgaaatcat
    31621 ttaaaggact acatgaagaa ggtaaatgat gaatttgagc ctttgacggt ggtcaataaa
    31681 aatccagatg aggacattgt agttctttca aagagcgaat gggacagtat tcaggaaacc
    31741 ctgagaatcg ctcaaaataa ggagttatca gacaaggttt tgcgaggaat ggctcaagtc
    31801 cgtgctggaa gcattcaggt ccatgtgatt gaggagtgat gaatgctact caagtttaca
    31861 gaagatgcgt gggcagatta ttgctactgg caaaaccaag ataaaaaaac actaaaaaga
    31921 atcaataaat taatcaagga tattcaacgc gatccattta caggaatagg aaaaccagag
    31981 ccactcaaat atgattacca aggagcctgg tcacggcgta ttgatgcaga aaatcgcttg
    32041 atttatatga tggatggaga tagcgtggct ttcttgtcct ttaaagatca ttactaagtc
    32101 tattgaaagg taggcttttt ctcaagtctc tactaaacta ctatttctaa aaaacaagtt
    32161 tattttggca aatgtgttcc aaattcccca aaacatattc tattttaggt ttgtgaaaat
    32221 cactttttta tggtagaatg taaaagaatg tatgtcattc ggaataacaa taaaatgagg
    32281 taaaaacatg gaaatcatgt cgcttgcgat tgctgttttt gccgtcatca ttggtttagt
    32341 cattggatat gtcagcatct cagctaagat gaaatcatct caggaagctg cagagttgat
    32401 gcttttaaat gctgaacaag aagcaactaa tttacgtgga caagctgagc gtgaagcgga
    32461 tttacttgtt aatgaagcca aacgtgaaag caagtctctt aaaaaagaag cactattgga
    32521 ggccaaagaa gaagccagaa aataccgtga agaagtggac gctgaattca aatcagaacg
    32581 tcaagaactc aaacaaatcg aaagtcgttt gacagagaga gctactagcc ttgaccgtaa
    32641 ggacgacaat ttgacgagta aagaacaaac acttgaacaa aaagaacaaa gtatttctga
    32701 tagagcgaaa aaccttgatg cgcgtgaaga gcaattagag gaagtcgaaa gacaaaaaga
    32761 agcagaacta gagcgtattg gtgctctgtc tcaggcagaa gcacgagata ttatcttggc
    32821 tcagacagag gaaaacttga ccagggagat tgccagtcgc attcgcgaag ctgagcaaga
    32881 ggtcaaggaa cgttctgaca aaatggccaa ggacatcttg gttcaagcta tgcaacgtat
    32941 cgctggtgaa tatgtagcgg agtcaacaaa ctcaacagtt catctgccag acgatactat
    33001 gaagggacgc attattggtc gtgaaggtcg taacattcgt acctttgaaa gtttgacagg
    33061 ggtcgatgtg attatcgacg atacaccaga agtggtgacc ttgtcaggat ttgatccgat
    33121 tcgtcgtgag attgcccgta tgactatgga aatgttgctc aaagatggtc gtatacatcc
    33181 agctcgtatc gaagagttgg ttgagaaaaa ccgtcaagag attgacaata agattcgtga
    33241 atacggtgag gctgctgcct atgaaattgg tgcgccaaac cttcatccag acttgatgaa
    33301 gattatggga cgtttgcagt tccgtacttc atatggacaa aatgttttgc gccattcgat
    33361 tgaggttgct aagttggctg gtatcatggc gagcgaactt ggtgaaaatg cggctcttgc
    33421 ccgtcgtgct ggattccttc acgatatcgg gaaagccatt gaccatgagg ttgaaggtag
    33481 ccacgttgaa atcggtatgg aattggcccg taagtacaag gaacccccag ttgtggtgaa
    33541 tacgattgct agtcaccacg gagatgttga agctgagagc gtgatagcag ttatcgtcgc
    33601 tgcagcagat gccttgagcg cagcccgtcc aggtgctcgt agtgagtctc ttgaaagcta
    33661 catcaagcgt ctccatgatt tggaagaaat tgctaacggc tttgaaggag tgcaaactag
    33721 ctttgccctt caagcaggac gtgaaattcg tatcatggtc aatccaggaa aaatcaagga
    33781 cgacaaagtc acaatcttgg ctcacaaagt tcgtaagaaa attgaaaaca atctcgatta
    33841 tccaggaaat atcaaggtaa ccgtgattcg cgagcttcgt gcagtagatt atgctaaata
    33901 aataagaaag agcagttgaa aaattactgc ttttttgtta cactagatag aaagactgta
    33961 aaggataatc tggctttttg ccattattct agagaaatgt tatttcacag attgactaaa
    34021 aggagacaca atggcagacc gaggcttact aatcgttttt tctggtcctt caggggttgg
    34081 aaaaggaacg gttagaagag agatttttga gagttctgaa aaccaatttc aatattctgt
    34141 atcgatgacg acacgcgcac aacgtcctgg agaagtggac ggtgttgact atttcttccg
    34201 tactcgtgaa gaatttgaag agctgattcg tcaaggacag atgttggaat acgcagaata
    34261 tgtcggcaac tactatggaa ctcctctgac ctatgtcaat gaaaccttgg acaagggaat
    34321 cgatgttttc cttgaaattg aagttcaggg tgctcttcag gtcaagaaaa aggttccaga
    34381 tgctgtcttt atcttcctga caccaccaga tttggatgaa ttgcaagaac gcttggtagg
    34441 tcgtggaaca gatagtgcag aagtgattgc ccaacgaatc gaaaaggcca aggaagaaat
    34501 tgccctcatg cgtgagtatg attatgcgat tgtcaacgat caggtgcccc tagctgctga
    34561 acgtgtcaaa tgtgtgattg aagcagaaca cttctgtgtg gatcgtgtca ttggtcacta
    34621 tcaggagatg ttaccaaaat ctccaactac ccgataaaat ttagaaaata ggtacaagca
    34681 aatgatgtta aaaccctcta ttgatacctt gctcgacaag gttccttcaa aatattcact
    34741 cgtaatcttg gaagcaaaac gtgcccacga attggaagca ggtgccccag caactcaagg
    34801 tttcaagtct gaaaaatcaa ctcttcgcgc tttagaagaa atcgaatcag gaaacgttac
    34861 aattcaccca gatccagaag gaaaacgtga agcagtgcgt cgccgtatcg aagaagaaaa
    34921 acgccgcaaa gaagaagaag aaaagaaaat caaagagcaa attgctaaag aaaaagaaga
    34981 tggtgaaaaa atttaaggtt ggggggactc aatcttattt tttctattgc aagaatgtac
    35041 tgacaaggag gaggtgagaa gatggcccta gctaagatta tcgtagatgt gcccttgatg
    35101 cagacggacc agccctatag ttacaggatt ccggaggaat ttgagggaat gctggaagtt
    35161 gggatgcggg ttcatgtgcc ttttggtaag ggtaatcgcc tgattcaagg gattgttctt
    35221 ggtttggagt cccaatcaga tggagaagag atggagcgag atttaaaaga tattgcagag
    35281 gtgctggatt tttctcctgt tctcacgcca gaacaactct ggctggctga ggagttacgc
    35341 aaatctgtct tctcctacaa aatctctatc ctcaaggcca tgcttccggg atttctgaat
    35401 tctagctatg acaagattct ctatcctctg gaaggcttga gtcaggaaga acgagtacgc
    35461 ctgtttgatt cagaagattc gctagccttt tcttctctgg atttaggtaa gcaagctgaa
    35521 atgatgcgtt tgactagaaa aggcctgctt ggtctggaat atcaggcagt cgatcaaaag
    35581 aaggtcaaga cccagtcttg gtatgaggtt gaccatgctc aattagaagg tgttgagatt
    35641 tctacacgtg ccaagaaaaa gttggaactg agagattatc tgctgtctca tccagagagc
    35701 gcttccttgg ctagcttgtt agagtcctac tcgcgagagc aagttaactt ctttgtggat
    35761 caaggtgctg ttactatagt ccaaaaggaa gttcgacgct cggctgctta ttttgaagga
    35821 attgaagcaa gtagaccttt ggagttaaat ccagaacaaa gacaggcgcg tgatgcggtt
    35881 gtgagttcta ttggcagttc tcaacctccc tttctacttc aagggattac aggaagtggg
    35941 aagaccgagg tttacttgca gattatccaa ggtgccctgg ataagggcaa gacagctatt
    36001 ttgctggtac ctgagatttc cttgactcct cagatgaccg agcgttttat agcacgtttt
    36061 ggggacaagg tagccattct tcactcagga ttatccaatg gtgaaaagta tgatgaatgg
    36121 cgcaaggtgg agcgtggcga tgcccaagtt gttgttggtg ccagatctgc tatctttgct
    36181 cctctgaaaa atctgggtgt catgattatt gatgaagagc atgaagcggc ttataagcag
    36241 gacagcaatc cccgttacca tgccagagag gtagctattt tacgggctca gtataatcaa
    36301 gcaactctgg tacttggatc tgcaacgccg agcttagaga gccgggcacg tgctggcaaa
    36361 ggcgtctatc aacacttacg tctaacccaa cgtgccaatc ctttggctac aatccctgag
    36421 gttcaagtga ttgactttcg agactatatc ggacaaaatg agacgtcaaa ctttacgcct
    36481 cctttgctag aggctatcca agaccgtctg gttaaaaaag agcagatggt tctcatgctc
    36541 aatcgccgtg gttattctag ctttgtcatg tgtcgggagt gtgggacggt ggatacttgt
    36601 cccaactgcg atatttctct gaccttgcat atggatacca agactatgaa ctgccattat
    36661 tgtggtttct cgaaggatat tcctcaggtc tgtcctaact gtaagagcca cagtattcgt
    36721 tactatggga cgggaactca gaaggcttat gatgagctag cagaactctt tccccaagct
    36781 cgcattttga ggatggatgt ggatacgact cgaaagaaag gcagtcacca agccttgctt
    36841 gaccagtttg ggcgagggga agcggatatt ttacttggta ctcagatgat tgcaaagggt
    36901 ttggattttc ccaatgttac cctagtcgga gttctaaatg cggatacggc cttgaatctg
    36961 cctgatttcc gttcttctga gagaaccttc cagctcttga ctcaggtggc aggtcgagca
    37021 ggtcgggctg aaaaagcagg tcaagtcttg atacagtcct acaatccgca gcactatgct
    37081 attcgatttg ccaaggatca agattacgaa ggcttttatg cctatgaaat gggaatcaga
    37141 cgacaactcg gctatccacc ttactatttc acgattggta ttaccctttc tcacaagaaa
    37201 gaagaagagg ttttcaaacg tgcctatgaa gtcatgaaca ttttgcggtc aggcttgtca
    37261 gagaccagtc ccattctggg gccaacgcca aaaccgattg cccgtaccca caacctctat
    37321 cattaccaga ttttaattaa ataccgttta gaagatgagc tggggccgac cctcaaccag
    37381 gtcctggcct tgactcaaga acgggaaaat agtgagctcc gtctcagcat tgaccatgag
    37441 ccgcagcaat ttttataaga aggagaagat atgacaaaac taatctttat ggggaccccc
    37501 gacttttcag caacagtctt aaaaggactt ttgacagatg accgttacga aattctagcc
    37561 gttgtgaccc agccagaccg tgctgttggt cgtaaaaaag ttatccaaga aaccccagtc
    37621 aagcaggctg ccaaggaagc aggattatct atctatcaac ctgaaaaatt atctggaagt
    37681 ccagagatgg aagatcttat gaagctagga gcagatggaa ttgtgactgc tgcttttggg
    37741 cagtttctcc caagcaaact ccttgatagc atggactttg ctgtcaacgt tcatgcctcc
    37801 ctccttccta gacaccgtgg tggtgcgcct atccattatg ccttgattca aggggatgag
    37861 gaagctggtg tgaccatcat ggaaatggtt aaggaaatgg atgcaggaga tatgatttct
    37921 cgtcgcagca ttccgatcac agatgaggac aatgttggca ccttgtttga aaaattggcg
    37981 ctagttggtc gtgatttgct tttggacact ctgcctgcct atattgctgg tgatatcaaa
    38041 cctgaaccgc aggatacgag tcaggttacc ttctctccaa atataaagcc agaggaagaa
    38101 aaactggact ggaacaaaac caatcgtcaa ctctttaacc aaattcgtgg aatgaacccc
    38161 tggcctgttg cccatacttt ccttaagggc gaccgcttta agatttatga agccctacca
    38221 gtagaaggtc agggaaatcc aggtgagatt ctctctatct gcaagaaaga attgattgtc
    38281 gcaacggctg aaggggctct atccctcaaa caagtgcagc cagctggtaa gcctaagatg
    38341 gacattgctt ccttcctcaa cggagttgga cgtacattga ctgtaggaga acgatttggt
    38401 gactaaagta gaaacggcta gaagtttagc tctagcagtg ctagaggatg tttttgtgaa
    38461 tcaagcatat tcaaatattg ccttaaataa acacctcaag gggagtcagc tctctgcagc
    38521 agacaagggc ttagtgaccg agctagtcta tggaacggta gcccgtaaac tgactctgga
    38581 atggtaccta tcccacttta tcgaagacag agaccagtta gacagctggc tctatgtcct
    38641 tcttctcatg agtgcctacc aactccgcta tttggacaag attccagatc atgctgtggt
    38701 caatgaagca gtggaattag ccaaactccg taaaaaaggc agtgaaaaat tggtcaacgc
    38761 tgtccttcgc cgtatcttgc gtgaaggctg gccagatatt gctagcatca agcgaaaaaa
    38821 caagcgtgac tccattgcct attctctccc agttttgcta gttgccaaac tcaaggaaga
    38881 atacggagag gagagagcaa aagccatctt tgaaagcctg ttagtgcgaa acaaagccag
    38941 tattcgtgta acagacctaa gtcgaaaaga ggaaatccaa gccttgttgg aggcgaatga
    39001 ttccctttta gcaaccactg gtctggttaa ggagcagggg cattttgcag ggcataattt
    39061 gtttgcggat ggagccatta ccatccaaga cgagtccagt cagctggttg ctccgacgct
    39121 tgatttacaa ggtgatgagc gagtgcttga tgcctgtgcg gctccaggtg ggaaaacagc
    39181 ccatatagcc tcttatctta cgacaggtca ggttactgct ctggacttgt acgaccacaa
    39241 gttggattta attcaagaaa atgcccaacg tctgggagtt gaagatcggg ttcaaactca
    39301 aaaattggat gccagaaagg tgcatgagtt ttttgaccag gattcctttg ataagatttt
    39361 ggtggatgct ccttgttcag gaatcggtct tttgcgccga aaaccagata tcaaatacaa
    39421 taaagaaacg gcagatttcg cgtccttgca ggaaattcag ttagaaatat taggtagtgt
    39481 ttgtcaaata ctaggcaaag gtggtataat aacttatagc acctgcacta tcgtctcaga
    39541 ggagaatttt caagtcgtta aggccttttt agagagtcat cccgagttcg agcaggtaaa
    39601 actagaacat gaatgtaagg atatcatgaa agacggctgt atcctcatta cacctgaatt
    39661 gtatggaagt gatggattct tcatcagtca atttcgcaag atatcggatt aggaaggaac
    39721 tgacacatgg aaatttcatt attaacagat gttggtcaga aacgaacaaa taaccaagac
    39781 tatgtcaacc actatgtcaa tagagctgga cgtaccatga ttattttagc tgatgggatg
    39841 ggaggtcatc gcgcagggaa tatcgctagt gaaatggcgg tcacagacct gggtgtagct
    39901 tgggttgata cccagattga tacagtcaat gaagtgcgtg aatggttcgc ccattaccta
    39961 gaaattgaaa atcaaaagat tcaccagctt ggtcaggatg aagcttacag aggcatggga
    40021 actactttgg aagtccttgc tattattgat aatcaggcta tctatgctca tattggtgat
    40081 tcgcgtatcg gcttgattcg tggagaagaa taccatcagt tgacgagcga tcattccttg
    40141 gttaatgaat tgctcaaggc tggtcaattg acaccagaag aggcagaagc tcatccgcaa
    40201 aaaaatatta tcacccagtc tattgggcaa aaagatgaaa ttcagcctga ttttgggaca
    40261 gttatccttg agtcaggtga ctatcttttg ctcaatagtg acggcttgac caacatgatt
    40321 tcaggcagtg agattcgtga tattgtaacc agtgatattc ctttagcaga taaaacggag
    40381 acacttgttc gttttgctaa caatgcagga ggtttagaca acattacggt tgcccttgtt
    40441 tctatgaacg aggaggatgc agaatgatcc aaatcggcaa gatttttgcc ggacgctatc
    40501 ggattgtcaa acagattggt cgaggaggca tggcggatgt ctacctagcc aaagacttaa
    40561 tcttagatgg ggaagaagtg gcagtgaagg ttctgaggac caactaccag acggacccga
    40621 tagctgtagc tcgttttcag cgtgaagcga gagctatggc agatctagac catcctcata
    40681 tcgttcggat aacagatatt ggtgaggaag acggtcaaca gtatcttgca atggagtatg
    40741 ttgctggact agacctcaaa cgctatatca aggaacatta tcctctttct aatgaagaag
    40801 cagtccgtat catgggacaa attctcttgg ctatgcgctt ggcccatact cgaggaattg
    40861 ttcacaggga cttgaaacct caaaatatcc ttttgacacc agatgggact gccaaggtca
    40921 cagactttgg tattgctgta gcctttgcag agacaagtct gacccagact aactcgatgt
    40981 tgggctcagt tcattacttg tcaccagagc aggcgcgtgg ttcgaaggcg actgtgcaga
    41041 gtgatatcta tgccatgggg attattttct atgagatgtt gacaggccat atcccttatg
    41101 acggggatag cgcggtgacc attgccctcc agcatttcca gaaacccctg ccgtccgtta
    41161 ttgcagaaaa ttcatctgta cctcaggctt tagaaaatgt tattatcaag gcaactgcta
    41221 aaaagttgac caatcgctat cgctcggttt cagagatgta tgtagacttg tctagtagct
    41281 tgtcctacaa tcgtagaaat gaaagtaagt taatctttga tgaaacgagc aaggcagata
    41341 ccaagacctt gccgaaggtt tctcagagta ccttgacatc tattcctaag gttcaagcgc
    41401 agacagaaca caaatcaatc aaaaacccaa gccaggctgt gacagaggaa acttaccaac
    41461 cacaagcacc gaaaaaacat agatttaaga tgcgttacct gattttgttg gccagccttg
    41521 tattggtggc agcttctctt atttggatac tatccagaac tcctgcaacc attgccattc
    41581 cagatgtggc aggtcagaca gttgcagagg ccaaggcaac gctcaaaaaa gccaattttg
    41641 agattggtga ggagaagaca gaggctagtg aaaaggtgga agaagggcgg attatccgta
    41701 cagatcctgg cgctggaact ggtcgaaaag aaggaacgaa aatcaatttg gttgtctcat
    41761 caggcaaaca atccttccaa attagtaatt atgtcggccg gaaatcttct gatgttatcg
    41821 cggaattaaa agagaaaaaa gttccagata atttgattaa aattgaggaa gaagagtcga
    41881 atgagagtga ggctggaacg gtcttgaagc aaagtctacc agaaggtacg acctatgcct
    41941 tgagcaaggc aactcaaatt gttttgacag tagctaaaaa agctacgacg attcaattag
    42001 ggaactatat tggacggaac tctacagaag taatctcaga actcaagcag aagaaggttc
    42061 ctgagaattt gattaagata gaggaagaag agtccagcga aagcgaacca ggaacgatta
    42121 tgaaacaaag tccaggtgcc ggaacgactt atgatgtgag taaacctact caaattgtct
    42181 tgacagtagc taaaaaagtt acaagtgttg ccatgccgag ttacattggt tccagcttgg
    42241 agtttactaa gaacaatttg attcaaattg ttgggattaa ggaagctaat atagaagttg
    42301 tagaagtgac gacagcgcct gcaggtagtg tagaaggcat ggttgttgaa caaagtccta
    42361 gagcaggtga aaaggtagac ctaaataaga ctagagtcaa gatttcaatc tacaaaccta
    42421 aaacaacttc agctactcct taaaagcaga tggataatca aaatgagtaa tcaatctttg
    42481 tcatgatttc atggcaaaga ttttttttga gtccagattt gtgatagaat agagggagtt
    42541 gataaaagga ggaaagcatg gaagaatcaa aagaattaaa tgccgtcatt gatgtgatta
    42601 tgctagcggg gactattctc cttaaaagtg gctcagaaat ccatcgtgta gaagatacca
    42661 tgattcgaat cgcgcattcg caggggattg tggattgcaa tgtccttgcc atgcctgccg
    42721 ctatcttttt ctctattgaa aataccaata tttcgcgcat gaagcgcgtg acctcctctt
    42781 cttataacat cgaaaaagtc tgcgatgtga accagatttc tcgtcagcta gttggggggc
    42841 agattgactt agaaacagcc tttaagcaat tgacggcctt gcaagctcaa ccccttccct
    42901 atactaagtt gcaggtaact ctggctgcga cctttagtgc tcctttcttt tcagttatgt
    42961 ttagcggaaa tatctacgac gcacttgggg caggagtggc gaccttattt ggttttgcct
    43021 tttccctcta tgtggaaaaa tttatccgaa ttccctttgt gacagccttt gctggagcct
    43081 ttgtctttgg gataattgcc cagttttggg ctcgctacac aggttttcct tcaacggcag
    43141 atttgattat agctggtgcg gtcatgccgt ttgtaccagg tattgccttg accaatgcgg
    43201 tccgtgatat tatgaccaac cacataaact ctggtatgag taagatgttt gaatccctgc
    43261 tcattaccct cgctttaggg gcaggaactt ctgtcgcctt ggtattgatg aactaatatg
    43321 acactaacaa cctttttatt acaagcagta gcaagttttc ttgccattat cactttttta
    43381 atcgtactca atgtgcaacg gtctatgctc ttacctggag ggattttggg catgactgtc
    43441 tggctaatct atctcttgct caaggaaccg accaatgtca ttgtagctac cttcattgca
    43501 gccattattg gttcttgtgt cagccagatt ttaagtattc tttataagac acctgctgtg
    43561 gtctttatct tggccatttt ggcaccgctg gttccaggtt atctctctta ccgaacaact
    43621 gccttttttg tgacagggga ctataataaa gcactggcaa gtgcgacctt ggttgtcatg
    43681 ttggctttgg taatctctat tggaatggct agcggaacag tgattctcag actgtatcat
    43741 tatataaaaa cacatcgagt atcgtagact ttacagaaat aaaagaattt tctgaaaaat
    43801 gagataaata aattaacaac gctttctata tgtgcgagaa taccgcactt atgaagaaat
    43861 tgcggctgat tttggtattc acgaaagcaa cttaatccgt cggagctaat gggttgaagt
    43921 aactcttgtt caaaggtggt gttacgattt caagaactcc tctcagctct gaggacacgg
    43981 taatgattga tgcgacggaa gtacaaatca atcgacctaa aaaaagaatt agcgaatgat
    44041 tctggtaaaa agaaatgcca cgctatgaag gctcaagcaa ttgtcacaag tcaagggaga
    44101 attgtttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt
    44161 tgcagaaata tcggacaagc tggtaaaatc ttggctgaca gtggttatca agggctcatg
    44221 aagatatatc ctcaagtaca aactccacgt aaatccagca aactcaagcc gctaacagtt
    44281 gaagataaag cctataacca tgcgctatct aaggatagaa gcaaggttga gaacattctt
    44341 gccaaagtaa aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttc
    44401 ggattacgaa tgaatttgat tgctggcatt atcaatcatg aactaggatt ctagttttgc
    44461 aggaagtcta ctactttcct tattgtctgt aagtctactg accttgttgt ttatcccagt
    44521 catggtttct agttcgggct cagagtttca aagtggatgg caagagcatc aattgattgc
    44581 tgagaaggtt agtaaaacac ttgataagac atttgataag gatgtcagag aaattccgac
    44641 cagtcagttt tatcaaaaat ttgtagatga gatggtaagg acttactcag gaaatttgat
    44701 cctccaggag ctgataactg tgaatggagc ttataaagct acttatatcg gtgaactctc
    44761 tagcaactaa tcattcttta aaatgatgac caataagagg cttgatttgg tgaatcaagt
    44821 cttttttctc tcttttactg ccatttgtga taaaatagta tagaacgatt ttttacatga
    44881 atgataaaac agaggtaaat atgacaatcg gtattgataa gattggtttt gcgaccagtc
    44941 aatatgtctt gaaattacaa gacttagcag aagcgagggg aattgaccct gaaaaattaa
    45001 gtaaaggact cttactcaag gaattgagta ttgcgcccct aactgaggac attgtgacct
    45061 tggcggccag tgctagtgac tctattttaa ctgagcaaga aagacaagaa gttgacatgg
    45121 tcattgtggc gaccgagtca ggaattgacc agagtaaggc tgcggccgtc tttgtgcatg
    45181 gcttgctggg catccagccc tttgctcgta gtttcgagat taaagaagcc tgctatgggg
    45241 cgacagctgc cctccattat gccaaattgc atgtggaaaa ttctccggag tccaaggtat
    45301 tggtcattgc cagtgatatt gccaaatatg gtattgaaac tccgggagaa ccaactcaag
    45361 gtgctggaag tgtagctatg ttgattacac aaaatccacg catgatggcc tttaataatg
    45421 acaatgtagc tcagacccgt gacatcatgg atttctggcg accaaattac tcgacaactc
    45481 cttatgtaaa tggtgtctat tctacccaac aatacttgga tagtttgaaa acgacttggc
    45541 ttgaatatca aaaacgctac cagcttactt tggatgattt tgcggctgtt tgtttccact
    45601 tgccttatcc taaattagcg ctaaaaggct tgaaaaaaat catggataag agcctgcctc
    45661 aagagaaaaa agatctctta caaaagcatt ttgaccagtc tattctctac agtcaaaagg
    45721 tggggaatat ctacacaggt tcacttttcc ttggactttt gtctctcttg gaaaatacag
    45781 atagcttgaa agctggggat aaaatcgccc tttatagtta cggaagtgga gctgtggctg
    45841 agttcttcag tggtgaattg gttgaaggat atgaagctta tttggataaa gaccgtttga
    45901 acaagctcaa ccaacgaact gccctatccg ttgcagacta tgaaaaggtc ttttttgagg
    45961 aagtaaactt ggatgaaaca aactctgccc agtttgctgg ctatgaaaat caagattttg
    46021 ccttggttga aattctcgac caccaacgcc gttatagcaa ggttgaaaaa taatgaagat
    46081 aagttggaat ggattttcta aaaaatcata ccaagagcgc ctcgagctgt taaaagctca
    46141 ggcgctcctt agtcctgaga gacaagctag tctggagaag gatgaacaga tgagcgtgac
    46201 tgtggcagac cagctgagtg agaatgtagt gggaactttt tctctgcctt attcactggt
    46261 tccagaggta cttgtcaacg gtcaggaata caccgttccc tatgtgacag aagaaccctc
    46321 tgtggttgcg gcggccagct atgccagcaa aatcatcaag cgtgcaggtg gttttactgc
    46381 acaagtccat cagcgacaga tgattgggca ggtagccctt tatcaagttg ctaatcctaa
    46441 actagcgcaa gagaagattg ccagcaagaa agcggagctc ttggagcttg ccaatcaagc
    46501 ctatccttct atcgttaaac gtggaggtgg ggcgcgtgat ctgcatgtcg agcagataaa
    46561 aggcgaacca gactttctcg ttgtttatat tcatgtcgat acccaggaag ccatgggtgc
    46621 caatatgctc aacaccatgc tggaagcctt gaaaccagtc ttagaagaac tcagtcaggg
    46681 acagagtctc atgggaatcc tgtccaacta cgcgaccgat tctctggtga ctgcaagctg
    46741 tcgcatcgcc tttcgctact tgagccgcca aaaggatcaa ggacgagaga ttgcggagaa
    46801 aattgcgttg gctagtcagt ttgcgcaggc tgatccttac cgagctgcta ctcataataa
    46861 aggaattttt aatggtattg atgcgatttt gattgccact ggtaatgact ggcgtgccat
    46921 cgaagctggg gcccatgcct ttgccagtcg agatggacgt tatcaaggtc ttagttgctg
    46981 gacgctggac cttgaaagag aagaattggt cggtgagatg accctgccca tgcctgtagc
    47041 gactaagggt ggctctatcg gcctcaaccc acgtgtagct ctcagtcatg atctactagg
    47101 aaatccttct gccagagaat tagcccagat tatcgtgtcc atcggtcttg cccaaaattt
    47161 tgcagccctc aaagccttgg taagtacggg catccagcaa ggccacatga aactacaggc
    47221 caaatcccta gctctcctag ctggggctag tgaatctgaa gttgctcccc tagtcgagca
    47281 gcttatcgca gataaaacct ttaacctaga gacagcccag cgctatctcg aaaatttaag
    47341 atcataaaaa actcagacga atcggtctga gttttcttgt gtttaaatac tttttcctgg
    47401 taatagtgta actggtaaga agtaaccagt tgtggcgact tccttgcctt caatcttttg
    47461 caagagaaga tcaatagtga gacaagcaat ctcttccaaa ggttgcttga tagtagccaa
    47521 ttgagggtag taattttcga taaagtaggt cccatcatag ccgatgacct tgagcttttt
    47581 tgggacagaa atgcccaatt cttgagcgat tttaatgacc agaatagctg tcaaatcatc
    47641 cgaagcaaaa atggcatctg gtttttcccg ggtcaagata ttcttgattt ccatctcttt
    47701 tctgacggga gaaaagtcac tggaaacatt gataatagga gcttttggga gtacggatgc
    47761 aaaaccagcg tggcgcagtc cggttggcga attagaattg tcattccctg taatcatgat
    47821 gatagactgg gcacctgtct tgaccaaggt ttgggcagca agaaccccac cagcatagtt
    47881 gtcagaggag acgacaggga tgtctggcga taggtttcgg tcaaaggaaa taatcggcgc
    47941 tgtcacacga ttgtagtctt cgattcctag gttgtgacta ccagaaatga tgccgtccac
    48001 ctgattggct tccaacattt cgatgtattc gcgttccttc tcagaatcat gttcactgtt
    48061 gcagatgatg gtcttgtaac catttttgaa gagttggtgt tccaatttat caatcaattc
    48121 tgcatagaaa acattggaaa tattggggaa aatcaagccg attaacttag ctgattttcc
    48181 ttgcagacta cgagctaggt tgttgggttt atagcctaat tctctcatgg cttcattgac
    48241 tttttggatg gttttctcag atagatatcc ttttttattg ataacccgag aaacggtagt
    48301 aggactgacg cctgcaagtt tggcgacatc agttagtttt gcgaccataa tctaattcat
    48361 agtaagttcc agttgggttt ccagatttga tcaggatacc attttggtcc gcatgtggga
    48421 agacacgacc agaaaatact ttttctcctt tattgatgaa aatttcaaag acagagttat
    48481 cgatgaagat tgtagcagta gtagcctgat tctcgatagg gcaagaacga gttgtcccaa
    48541 attcttgggc atactgttct ccagcctggc tacgatccac tgtcacttga ccgtttacaa
    48601 ggtcaaagtt gattgaaagt cccttacctt ctttatcagc aagtaagaca atctcgctct
    48661 ggctattagc ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg gaacggtttg
    48721 agaaggcttc ttcagaagca cgaaggtcct taatagcagc gactggatac tggtagagct
    48781 tgtcgtcttt gatagtgagt tccttgacca aagagaaggt tccttggtgg tcaaaacggt
    48841 cagatgggta agaaacatct ggcaaaccaa gccagctaac tgctagagca cgcccatcag
    48901 gagcgttgaa ggcttgagtt gcataggctt cgaaaccgta atccatgttt tgaagttgag
    48961 acacatctac cattttggca tttttagggt caaaggaagc cccaatctta tacatatttg
    49021 gaaagatatt atcgtagtct agaactttct tatccaatcc ttgtggacag tagagaagga
    49081 caggttgttc ctctacaaag accagattag gacattccat catgtaggca gtacggtcgt
    49141 tagcaaagtc aaggtcgcca actgcttgcc agtttgtgta gtcgttattg acagccttgt
    49201 agagacgaac gaaacctttt ttctccaagt cctgtccacc gacgacagca tagtattgac
    49261 ctttaaagtt aaaaatttgt ggatcgcgga agtggtcagt agagtctgct ggctggtcaa
    49321 tcaagatctt gtcaatcttt gtaatcttac cctccttgtc catcaaagca ccgatctggt
    49381 atgggtgacg gatccagttt tcatcgcgaa catttcctgt ataaaatagg aataagttat
    49441 cgccaaattg catggcagaa ccagagtagg caccgtggct atctaatgga gtatctggta
    49501 aaactttgat tccagtttct ttaaagtgaa ccaaatcatc actttctagc tgtgcccaag
    49561 attttaaacc gtgggctgca ccaaaaggaa aattctggta aaagaggatc cacttgccat
    49621 caaagtaaga aaagccattt gggtcgttga gaagtcctgt ttttggctca acatggtaat
    49681 gagtatgcca tggagattgt gccatatttt cctttatatg ttgaatttct tcttgcgtcc
    49741 aatcttgata aagtctgtaa cgacgctcag ttgtccattc cattcattcc tccaaaaatc
    49801 ttatcacttt taatagtaac tgttttcgat aaaaaatgca agccttttat gttaaaaaag
    49861 agaaaaaact gtcaaacgat tatcataaaa taaatacagg aaatcaatta aatttttacg
    49921 aaaatgtgaa agataatgaa ataaaagact ttttaaccaa ggtttcaaac ttatttttca
    49981 aggaattcct gatgaaacag tcaaaaacaa tcaatctaaa gcttgcccat taagtggata
    50041 gaatattttt tatgcaaaac gcttgacata tttttaaaac atgataaaat aatagtcgta
    50101 agggcgaata aaatcgcttt caaacaagaa caaaatgtta tataaggaga tttttgctat
    50161 ggattatagt aaagttgctg ccgaggtcat tgaggctgtc ggtaaggata atcttgtagc
    50221 tgcagctcac tgtgcgacac gtcttcgctt ggtattgaaa gacgaagcaa aagtgaatca
    50281 agcagctctg gataataatg cggatgtcaa ggggactttt agcactaacg gacaatatca
    50341 aattatcatt ggtcctggtg atgttaactt cgtatatgcg gaaattatta agaaaactgg
    50401 tttgaaagaa gtttcgacag atgatttgaa agagattgct aataaagaca aaaagttcaa
    50461 tccattgatg gacttgatta aacttttgtc agacattttt gttcctatta tccctgcctt
    50521 agttgcaggt ggtctcttga tggctttacg gaacttcttg acatcaccag atttgtttgg
    50581 acctcaatca attgaagata tgtatcctgc tatcaaaggc ttctcagcta tgattcaatt
    50641 gatgtctgct gctccattta tgttcctccc tgttttggtt ggtatttcag cagccaagcg
    50701 ctttggagca aaccaattcc ttggtgcggc aatcggtatg attatgacca ctccagattt
    50761 gggtggtaaa gaagccttct gggacatctt aggtttccat gttacacaaa caaactatgc
    50821 ttatcaggtt attccagtcc ttgttgcagt ctggttgtta gctaatttag aaaaattctt
    50881 ccacaagaaa ttgccatctg cagttgactt cacttttaca ccgcttttat cagtgatgat
    50941 tacaggattc cttaccttta cagttatcgg tcctgttatg ttggttgtgt ctgatgcgat
    51001 tacaaatgcg attgtatggt tgtacaacac aacaggtgcc tttggtatgg ggctatttgg
    51061 tggaacttac tcattaatcg ttatgacggg tcttcaccaa tcattcccag caatcgaaac
    51121 acaattgttg tctgcataca ataataacgg tactggattt ggagactaca tctttgttgt
    51181 tgcttcaatg gcaaacgtag cacaaggtgc ggctactctt gcagtctact tcttgacaaa
    51241 aaatgctaaa acaaaaggat tgtccagttc ggctgctgtt tctgccttcc ttggtattac
    51301 agaacctgct ctctttgggg taaacttgaa atacaaattc ccattcttct gcgcccttgc
    51361 tggttcagca attggtgcct ttgtagcagg tttaactcac gttattgcag tttcattggg
    51421 agcggctgga tttattggat tcctttctat taaggctggt tcaatcccta tgtatataat
    51481 tgcggaaatt atgtcctttg ttgccgcctt tgctttcact tatttctacg ggaaaacaaa
    51541 agcagctagt gtctttgctg atgaagctgc cacagcaacc gcagaaacag ttacagaacc
    51601 tacagtagaa gcaccagtag tggaagagac tgatactctt caaaatgaaa cacttgtaac
    51661 tcctatcgtt ggtgatgttg tcgctcttgc tgatgtcaat gacccagtct tctcaagtgg
    51721 agctatggga caaggtatcg ctgtgaaacc aagccaaggc gtggtctatg caccagctga
    51781 tgctgaagtt tcaattgcct ttccaacagg gcacgctttt ggtttgaaaa caagaaatgg
    51841 tgctgaagtt ttgattcacg ttggtattga cactgtatct atgaacggtg acggttttga
    51901 agcaaaagtt gctcaaggta ataaggtgaa agctggcgat gttcttggaa catttgactc
    51961 aaacaaaatc gctgcagctg gacttgatga tacaacaatg gttatcgtta caaatacagc
    52021 tgactacgct tcagtagctc cagtcgcaac aggttcagtt gcgaagggga atgctgtgat
    52081 cgaagtgaaa atctaatcaa tcctctctaa tgtgaaaacg aacaaatgac atgtttgttc
    52141 gtttttatta gatagtaaga tttacagagg aaaatctaaa aaatagagac atttagactt
    52201 tcgaagtatg ctataataaa gaaaataaaa acaagaggtt tatcatgaca aaattatatg
    52261 gaagcttgga agcgggcggt acaaagtttg tctgtgctgt cggtgatgaa aactttaacg
    52321 ttgtagaaaa aacacaattt ccaacaacaa ctccaatcga aacaatcgat aaaaccattg
    52381 agttcttctc aaaattcgat aaccttgctg gtcttgcagt tggttcattt gggccgattg
    52441 atattgacaa aaactcaaaa acttatggct ttatcacgac gactccaaaa ccaaactggg
    52501 caaatgtgga cttgcttggt gcccttcgtc gcgccctaaa cgtgccaatg tacttcacaa
    52561 cagacgtaaa cagctctgct tacggtgaaa tggttgcccg taacaatgct ggtggtcgta
    52621 tcgaaaactt ggtttactac acaatcggta caggtatcgg tgcaggcgtc atccaacgtg
    52681 gtgagtttat cggtggtgtg ggtcaccctg aaatgggtca ttattatgtt gctagacacc
    52741 caatggatat tgaaaaagag tttaagggtg tttgtccttt ccataaggga tgtctagaag
    52801 gttatgcagc tggtccaagt ttggaagctc gtacaggtgt acgtggggaa actattgaac
    52861 tcaacaaccc tgtttgggat gttcaagcct actatatcgc tcaagctgcg gttaatgcga
    52921 cagtgacttt ccgcccagac gtgattgtct ttggtggagg ggtcatggct caacaacata
    52981 tgctggaccg tgtccgtgag aaatttacat ctcttcttaa tggttaccta ccagtaccag
    53041 atgtgcgtga ctatatcgtg acgccagcag tcgcaggaaa tggttctgcc acacttggga
    53101 actttgttct tgcaaaagaa gtttcaaaat aaagcacaaa atccgcttgg gaaaccaaac
    53161 ggattttgtg gttgaaaaca atatttttga gcctttcctt aagtgattac ggacggtagc
    53221 gactttcttc gaaattccat acctaaactt tgagcctagt gtctcaaagt ttccgaatac
    53281 ctgaaaccat tagatttcag gtgtttctat cacggcggaa aggctaggta agtcctcgcc
    53341 tcactatcga aaaatatgca tgatttccat accaaagtat atttagtatc aagctatagt
    53401 taatctacgc tttaaaaatc cacttgggaa accaaacgga ttttttacgt gtcaaagcat
    53461 ttgccagaaa aagtcaataa tataggtcag accgtaggta taaaccacga gggtaaaggg
    53521 tttggtcaga atgatgatgg tcatgtagcg cttgaaactc atcttggtca gggcagccag
    53581 catacagaga aagtcagctg ggctaatggg ccaaatcatc ataaaaataa agaagcggtc
    53641 aaaacgattg cccttatcta gccagccgat gtacttgtcg taggtgcgct tgctgacgac
    53701 agactggaca aaggcagctc cgtataggcg cactagataa aagataatgg cacagccaat
    53761 cacgatgccg atatagttgt agatagtccc gatgatgtgc ccgtagataa agaccccagc
    53821 caccgaggtc aaggcccctg gaatgatagg gacgacagtc tgtaaaatct gtaaaaagat
    53881 aaagagaggt ggaccccaga tgcctgcctg ctggataaag gcagagaggg tttccttgga
    53941 ttgtaaaatc ccagcctgat aagcccaaat acagaaaatc aaactcccaa ccccaccgac
    54001 aatcgatgag atattgataa ctcgctgcag aaggggagaa acagctttca tttgtttatc
    54061 ctgtgacatg taaactcctc atagatagta tatttctact ataccatatt ttggaggaga
    54121 aagggggaat gagtcttttt tgataaggaa tagaaagtaa atagcccttc gagacttaga
    54181 ataggtctgt caactaaagg ttatatgcat tctaggtttc gaataatcgc aattccataa
    54241 atttaaaagc attctaagtt tcgaatagct tatctgagat aattttgagg cattcgcgct
    54301 ttcgaatagt cattttccct aaagtttaga tgtattctga agctagaaag actaaaatct
    54361 aaaagtagta agagtctctc tctgatggac gtaatttatg gctagtatga atcctttgaa
    54421 ttgttagtta attttaatat taatcagttc tgaaataatt actaaatata gttagatggt
    54481 gaattaatta ttgctaaatt tcaagttcaa gttagtcatc cagaagtctt ctctggggga
    54541 cttgtagttc aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc
    54601 ctttgtagtc gttttcttag ttccctgagg taaccatcta tgaatgaact tgttgtgatt
    54661 tttattagat cctatagtgg tgtgcataat agatatagca gattgaaact agaatagtat
    54721 acatctactt ctaaaacatt gttagaaatc aatttgactg tcctgatcaa tttgtcctgt
    54781 tcttatttca ttttactata taatccttag aaaacatatc ggacaagcgg ttgaattccg
    54841 ttccgtccat tagtagataa aggattactc cttcttgaaa tgacagatga acttgtttct
    54901 tataaaaatg ttatctgaaa ctattcgctt ttttccagaa gttttagagg aagaaaactt
    54961 tatgaggaaa aaggagttac tcaaataaca attcaggatt aaaaatagac agttgaggag
    55021 cggaaggtat aaattaagtt tgctactgta taatggattt atcactaata ctcttcgaaa
    55081 atctcttcaa accacgtcag cttcgccttg ccgtagatat agttactgac ttcgtcagtt
    55141 ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt cagttttatc tgcaacctca
    55201 aagctgtact ttgagcagcc tacggctagc tttctagttt gctctttgct tttcattgag
    55261 tataaaagtg ctccaggcca tattttacac agcaatagtc ttctaaaaat ggacaaaaaa
    55321 cattgtaaag gctatcaaaa aggagtataa tgagtgcaag aaatttcgga ggtgaaagat
    55381 gctagaagta agaagtctag agaaaagttt tggctccaag caagttttgt ttggtattga
    55441 ctttcaagcg cgaccaggtc gtattttggg actagtcgga aaaaatggtg ctggaaaaac
    55501 aacgattttc catagtattt tgaaattcct agaatatcag ggagaaatcg gtctagatgg
    55561 tcaggatatt cgtcaggaga cctatgctcg gattggttat ctgcctgaag aacgcagtct
    55621 catgcctaaa ttgacagttc ttgaacaagt tcgctacttg gcgactctaa aaggcatgga
    55681 tgccaaagaa gtcaaagaaa aactccctca atggatgaag aggttggaag tgaaaggaaa
    55741 gctgacagat aaaatcaaga gtctgtcaaa aggaaatcag cagaagattc agctcattat
    55801 tactctgatt catgaaccag acctgattat cttggatgag ccttttagtg gattggaccc
    55861 agttaataca gaattgctca aacaagtcat ttttcaggaa aaagagcgcg gagcaaccat
    55921 tatcttttct gaccatgtca tgaccaatgt tgaggaactt tgtgacgata ttctgatgat
    55981 ccgagatggc cgtgtggtct tgcacggacc agttcaggat gtccgcaatc aatacgggaa
    56041 aacgcgtctc tttgtttcaa gtgaacgaag caaggaagaa ttggaaaatc ttcctcatgt
    56101 caaacaggtg agcttgacca aacaaggcag ttggaaattg attttggagg atgagagcgc
    56161 tggaagggaa ctcttcccaa tcttgactca aggtcaatat atcgcaacat ttgaccaaca
    56221 agcgccaact atcgatgaaa tctttaaact agaatcagga gtggaagtat gagaaatatg
    56281 tgggttgtaa tcaaggaaac ctatcttcga catgtcgagt catggagttt cttctttatg
    56341 gtgatttcgc cgttcctctt tttaggaatc tctgtaggaa ttgggcatct ccaaggttct
    56401 tctatggcta aaaataataa agtggaagta gtgacaacag tgccatctgt agcagaagga
    56461 ctgaagaatg taaatggtgt taacttcgac tataaagacg aagcaagtgc caaagaagca
    56521 attaaagaag aaaaattaaa aggttatttg accattgatc aagaagatag tgttctaaag
    56581 gcagtttatc atggcgaaac atcgcttgaa aatggaatta aatttgaggt tacaggtaca
    56641 ctcaatgaac tgcaaaatca gcttaatcgt tcaactgctt ccttgtctca agagcaggaa
    56701 aaacgcttag cgcagacaat tcaattcaca gaaaagattg atgaagccaa ggaaaataaa
    56761 aagtttattc aaacaattgc agcaggtgcc ttaggattct ttctttatat gattctgatt
    56821 acctatgcgg gtgtaacagc tcaggaagtt gccagtgaaa aaggcaccaa aattatggaa
    56881 gtcgtttttt ctagcataag ggcaagtcac tatttctatg cgcggatgat ggctctgttt
    56941 ctagtgattt taacgcatat tgggatctat gttgtaggtg gtctggctgc tgttttgctc
    57001 tttaaagatt tgccattctt ggctcagtct ggtattttgg atcacttggg agatgctatc
    57061 tcactgaata ccctgctctt tattttgatc agtcttttca tgtatgtagt cttggcagcc
    57121 ttcctaggat ctatggtttc tcgtcctgag gactcaggga aagccttgtc gcctttgatg
    57181 attttgatta tgggtggttt ttttggagtg acagctctag gtgcagctgg tgacaatctc
    57241 ctcttgaaga ttggttctta tattcccttt atttcgacct tctttatgcc gtttcgaacg
    57301 attaatggct atgcgggggg agcggaagca tggatttcac ttgctattac agtgattttt
    57361 gcggtggtag caacaggatt tatcggacgc atgtatgcta gtctcgttct tcaaacggat
    57421 gatttaggga tttggaaaac ctttaaacgt gccttatctt ataaatagaa gagccttgcg
    57481 aaagcgaggt ttttaaaggt gaaaagggtg gaatcacgaa cctaattatg tacacattat
    57541 gtaaacaagt tgcttgaaaa ctcaattgta tagtgaactg aatctggaat aggataatat
    57601 tacttctaaa acattcttac aaattgattt gaattccaaa atcccatcgt tccgttctta
    57661 tttcattttg cgatatagtg aaaggaaata agtcaactca caaaaaacgc ataatatcaa
    57721 ggatttttaa cacttgatac tatgcgtttt ctaattttaa agactttttg cctggtctct
    57781 tttgttctat gagtatgtta catatctagg taaaaattat ttaaagcaaa ttaaccttat
    57841 ttctcaagat gtagtaggtt ccgagataaa agatagctat gaatatgagt tctttaacaa
    57901 tggctatacc tgctcccata tagaaatggt cattgagtcc taccagtgaa ttgacataga
    57961 aattagaact aagattgaag aaaagttcaa taaatccaat gacgatttgg ataccaatgt
    58021 aggctgcaac agcgagtgct gtacggtatt cattgaaaag ctgtccaatg gaaatagcca
    58081 ggtagatgca gaggattcct gaaatggtat ttagtaggaa ggatatacct gtaagaaaga
    58141 tctgagggag atgtgtttct acaaatgtaa tcacataaga aagaggaatc cattctggag
    58201 ctgttaaagc cagaataata acagcactta gagccaatac agcggtgcta atcaatgacc
    58261 agataaaggc accgattagt ttggctgtga tgatatggtg ttcagaaact ggcaaggtca
    58321 aagtcagata gccttgtcgg tcgtagacac tacctttgaa gcgtttaata atcaagaaaa
    58381 tggttgaaat cgcaagtgta agcatcaagc caccaaagac tgtagctaga aaaagtagca
    58441 tagtagcctg actttcttgg taaggtagat ttttaaagcc ttgtgtctgt attccgatga
    58501 gggcagaaag gactagcacg gctgcgtaga gggctaaata ccacttgtta acatttttaa
    58561 attcgtagtg aactaaattc caaaacataa ataatctcct ttgcttaggc cttaaattcc
    58621 tgacggaaga gttggtcaat ggattcacct gactcgtagc gaatatcatc tacatttcct
    58681 tgacggacga cttttccgtc ttttaggaag acaatttcat ccaagattgg ctcgatatca
    58741 gaaatcaagt gggtagaaat caaaacggta gaagttggtg agtagttgtt gataatggta
    58801 ttgaggatat aagcacgggc tgctggatcc accccaccaa tgggttcatc caaaacatag
    58861 agacgagcat cacggctcat aaccaaaatc agttgaacct tttctttgtt tccttttgat
    58921 agtttcttga gacgactatt ttcatcaatg cccaggtctg caagtagatg atgagcgcgt
    58981 tcaagattga aatctttata gaaggtcttg aagtaggtta gggcttcttt gaccttcatt
    59041 tgctcattga gataagtcgt atcaggcaaa taagctacaa cggccttggt tgctgggctt
    59101 gggtccatgt cgttgatgag gacacgtcct tgatctggtt gtaagaggcc attaattagt
    59161 ttaatcaggg ttgtttttcc tgagccgttt ggcccaagaa ggccgacaat ttttccagct
    59221 ggaatgtcaa gagaaacatt ttcaagggct ggtgttgctc catatgattt ggatacattt
    59281 tcaaatgcta gtaatgacat aggcttaaac tcctttaata taatcactga ctacgcctgg
    59341 tagttcttct ttttcatagc caaaatgggt catggaggaa acgaagtgtt ccaattcttc
    59401 ttctgataat tgtttgcgtg actgggcgat tagctcctta tccttagtca caaatcgtcc
    59461 agttgttcgc ttgctgtaga caaatccttc tcgttcaagg tctgataagg ctctttggat
    59521 ggtattggga ttgacaccag cctcgctagc tagctccctc acggttggaa gttgttgatt
    59581 gggttccagt gtatgggaaa caatctgaag cttgattttc tccataatct gtaaatagat
    59641 gggttttttg ttgtcaaatg tccaggacat cttagtctcc tttcttttac cctattgtct
    59701 taattaaata atacaacaaa acaaaaaact tgtcaagcaa aaagaagaat tgttttggga
    59761 atcgcttaaa aaatggtata atgaaaagaa aacgataagg agggaaagga tgcgttgtcc
    59821 aaaatgtggg gctaccaagt caagtgttat cgatagtcgc caagcagaag aagggaacac
    59881 cattcgtaga agacgtgagt gcgacgaatg ccaacaccgt tttacaacct acgaacgagt
    59941 agaagaaaga accttagtgg ttgttaaaaa agatggcaca cgggaacaat tctccagaga
    60001 taaaatcttt aatgggatta tccgctcagc ccagaaacgt cctgtgtcaa gtgatgaaat
    60061 caacatggta gtcaatcgta tcgaacagaa actccgtggt cgaaatgaaa atgaaattca
    60121 aagtgaggac attggttcac tcgtcatgga ggagttggct gaattggacg agattaccta
    60181 tgtacgtttt gctagtgtct atcgtagttt taaggatgtc agtgagttag agagcttgct
    60241 ccaacaaatc acccagtcct ctaaaaagaa aaaggaaaga taaatgaagc caattgaccg
    60301 tttttcttat ctaaagaata atcgggtgtc gcaagatacc tcatctctgg tacagtgcta
    60361 cctcccgatt atcggtcagg aggcactgag cctttatctt tatacgatta gtttttggga
    60421 taatggtaga aaggaatatc ttttttcaag tatcctcaat catctcaact ttgggatgga
    60481 tagactgata aaatcattga aaatcttatc tgcttttaat ctcttgactc tctatcaaaa
    60541 gggggatgtt tatcagctag ccctccatgc tcctctatct agtcaagact tcttggggca
    60601 tcctgtttat cgcagactct tagagaaaaa gattggcgat gtagctgtgg aggatttgaa
    60661 agttgaaagt gctgatggtg aagaaatacc tgtctcactc aatcaagtct ttccagaatt
    60721 ggcagaacta ggcagtcaag aagaccttgg tctcaagaag aaagtggcca atgattttga
    60781 cttggaacat tttcgccagc tgatggctcg agatggactt cgttttgcgg atgagcagtc
    60841 cgatgtctta aacctctttg ctattgccga ggagaagaaa tggacttggt ttgaaaccta
    60901 tcaattggcc aagtcaacag ctgtttctca ggttatttca accaaacgca tgcgtgaaaa
    60961 aattgctcaa aaaccagttt catctgactt tagtcttaag gaaacaacca ttatcaaaga
    61021 agccaaaagt aaaactgccc tgcagttctt ggcagaaatc aagcaaacac gcaagggaac
    61081 cattacccaa acagaaagag aactcttgca acagatggct ggcttgggct tgctggacga
    61141 agtcatcaat atcattcttt tattgacctt taataaggtc gattcggcaa atatcaatga
    61201 gaaatatgcc atgaaggtag ccaatgacta tgcctatcaa aagattcatt cggcagaaga
    61261 ggcagtcttg cgcatccgtg agcgaggaca gaaagcaaaa acacaaaaac agaatcagac
    61321 tgccccagta aaaaccaatg ttcctaaatg gagtaatcct gaatataaga atgaaaccag
    61381 cgaggaaact cgtctggaac tagaacgtaa gaagcaagaa ctattagctc gattagaaaa
    61441 aggaggagat tagatggaaa gtgtcggaga cgtactcaaa cgtcaaccca gccgttttta
    61501 ttatcaagat ttggtccaga aaatcatgaa ggaccctgat gttgcggctt ttatccagca
    61561 agaatccttg actccagagg aattaaatcg cagtatctcc aagtttaatc agtacatcac
    61621 cgagcgtgac aagtttctcc gaggagatac agattatatt gccaaaggct acaagcctat
    61681 actagtcatg aaccatggct atgcggatgt ttcttatgaa gaaactcctg aactaatcgc
    61741 ggcggaaaaa gaagcggcta ttaagaaccg tctcaagtta atcaatctac cagccagtct
    61801 caagaaagct agtttggctc aagttgactt ggatgatttg gggcgcttac cagtttttga
    61861 aaagctacta gccttcgtgg agcaatatcc agctattcga aaaggtcttt acctatatgg
    61921 agattttggt gtgggtaaaa gtttcatggt ggctgcccta gctcatgatt tatcagaaaa
    61981 acgtggtgtt tcatccactc tcctccacta tcctagcttt gtcattgatg tcaaaaatgc
    62041 tatcagtgat ggcaatgtta agaccttggt ggatgagatt aagctgtctg aggtcctgat
    62101 tttagatgat attggcgccg agcaatccac cgcttgggtg cgtgacgaaa tcctgcaggt
    62161 cattctccaa tatcggatgc aggaaaattt accgaccttt ttcacatcca acttcaactt
    62221 tgaagattta gagaagcatt ttgcgaaagt gaaacatgga aatgacgaaa cctgggaagc
    62281 cagacgcgtc atggaacgca tccgttattt ggctgaagag actcgtttag aaggagtaaa
    62341 ccgtcgatga cagaaacaat caaattaatg aaggctcata cttcagtgcg caggtttaaa
    62401 gagcaagaaa ttccccaagt agacttaaat gagattttga cagcagccca gatggcatca
    62461 tcttggaaga atttccaatc ctactctgtg attgtggtac gaagtcaaga gaagaaagat
    62521 gccttgtatg aattggtacc tcaagaagcc attcgccagt ctgctgtttt ccttctcttt
    62581 gtcggagatt tgaaccgagc agaaaaggga gcccgacttc ataccgacac cttccaaccc
    62641 caaggtgtgg aaggtctctt gattagttcg gtcgatgcag ctcttgctgg acaaaacgcc
    62701 ttgttggcag ctgaaagctt gggctatggt ggtgtgatta tcggtttggt tcgatacaag
    62761 tctgaagaag tggcagagct ctttaaccta cctgactaca cctattctgt ctttgggatg
    62821 gcactgggtg tgccaaatca acatcatgat gtgaaactga gactgccact agagaatgtt
    62881 gtctttgagg aagaatacca agaacagtca actgagacaa tccaagctta tgaccgtgtg
    62941 caggctgact atgctggggg gcgtgcgacc acaagctgga gtcagcgcct agcagaacag
    63001 tttggtcaag ctgaaccaag ctcaactaga aaaaatcttg aacagaagaa attattgtag
    63061 aaagtgagaa attatggccc taccaactat tgccattgta ggacgtccca atgttgggaa
    63121 atcaacccta tttaatcgga tcgctggtga gcgaatctcc attgtagaag atgtcgaagg
    63181 agtgacacgt gaccgtattt atgcaacggg tgagtggctc aatcgttctt ttagcatgat
    63241 tgatacagga ggaattgatg atgtcgatgc tcctttcatg gaacaaatca agcaccaggc
    63301 agaaattgcc atggaagaag cagatgttat cgtctttgtc gtgtccggta aggaaggaat
    63361 taccgatgca gacgaatacg tagcccgtaa gctttataag acccacaaac cagttatcct
    63421 cgcagttaac aaggtggaca accctgagat gcgaaatgat atctatgatt tctatgccct
    63481 cggtttgggt gaaccactgc ctatctcatc tgtccatggt atcggtacag gggatgtgct
    63541 agatgcgatc gtagaaaatc ttccaaatga atatgaggaa gaaaatccag atgtcattaa
    63601 gtttagcttg attggtcgtc ctaacgttgg aaaatcaagc ttgatcaatg ctatcttggg
    63661 agaagaccgt gttattgcta gtcctgttgc tggaacaact cgtgatgcca ttgataccca
    63721 ctttacagat acagatggtc aagagtttac catgattgat acggctggta tgcgtaagtc
    63781 tggtaaggtt tatgaaaata ctgagaaata ctctgttatg cgtgccatgc gtgctattga
    63841 ccgttcagat gtggtcttga tggtcatcaa tgcggaagaa ggcattcgtg agtacgacaa
    63901 gcgtatcgca ggatttgccc atgaagctgg taaagggatg attatcgtgg tcaacaagtg
    63961 ggatacgctt gaaaaagata accacactat gaaaaactgg gaagaagata tccgtgagca
    64021 gttccaatac ctgccttacg caccgattat ctttgtatcc gctttgacca agcaacgtct
    64081 ccacaaactt cctgagatga ttaagcaaat cagcgaaagt caaaatacac gtattccatc
    64141 agctgtcttg aacgatgtca tcatggatgc cattgccatc aacccaacac cgacagacaa
    64201 aggaaaacgt ctcaagattt tctatgcgac ccaagtggca accaaaccac caacctttgt
    64261 catctttgtc aatgaagaag aactcatgca cttttcttac ctgcgtttct tggaaaatca
    64321 aatccgcaag gcctttgttt ttgagggaac accgattcat ctcatcgcaa gaaaacgcaa
    64381 ataaaaaagt agaatctgga atgacagttc cggatttttt tgatataata aaataataga
    64441 aaacgctatc aaaagaagga gggtgatgtc ggtgatggaa catttgttta aattcttact
    64501 tttagcaccg tacttttatt ttgataactg gattgagaag gccaacagaa atagtaagtt
    64561 ttttccaatt ttttattatt tttactggtt ttacatcccc ttctattctc tttttagcct
    64621 tgcttggaca gttgtttcag ttctgttttt caataccgtc ttgagaaatg tgacagatat
    64681 caagttatgg ggcatttggt ttctttttat tctgctagct attggtatga attggttaac
    64741 ttattcctgt ttcaaagaaa tgtttcgctt gagacaggaa ctagggaagt ctaagggtgg
    64801 aaggcattga tttatatcgg tttctatttg taggaggtgg cttatggtac ctctaaaatc
    64861 atttattaca cgctattcca aggtttatat tggtaataac atttaataga acgaaactaa
    64921 agaaaacaat ttaaaaaagg aggcttgtga tggaacactt gtttaaaatg ataatcttat
    64981 taccctgttt ttactttttc agctggattg acaaggataa tagagaaagt aaatttttcc
    65041 caatttttta ctatttttac tggatttaca tcaccctcta tgctcttttt agccttgctt
    65101 ggacagtttt ttcagttctg tttttcaata tcgtcttgag aaatttgaca gatatcaagt
    65161 tatggggtat ttggctatta ttactactta tcgcttttgc tagtgactgg ttagactata
    65221 tctgtttcaa aaaaatgctt gacttgagac gggaactagg gaagtctaaa ggcgtaaggc
    65281 attgatttat actcttcgaa aatctcttca aaccacgtca acgtcgcctt ggattatata
    65341 tgtaactgac ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag caacttgcgg
    65401 ctagtttcct agtttgctct ttgattttca ttgagtatta tattactttc tatttgtagg
    65461 aggtggctta tgaagattcc tctcttaact ttggcaaggc ataaatttgt ttatgtcttg
    65521 cttactttgc tttttcttgc tttggtttat cgtgatgttt tgatgactta tttctttttt
    65581 gatattcatg cgcccgatct agctaaattc gatggacaag caattaaaaa tgacttatta
    65641 aaatcagcat tagattttcg tattctccag ttcaatctag gtttttatca atcatttatt
    65701 attccaatca tcattgtttt gctaggtttt caatatattg agctgaaaaa taaagtttta
    65761 cgattgagta ttggaagaga agtgagttat caagggttaa aaagaaagtt gactttgcaa
    65821 gttgcaagta tcccttgttt gatatattta gtgactgtgc tgataattgc aattataacc
    65881 tatttctttg ggactttttc tcctcttgga tggaattctc tattttctga tggaagtggt
    65941 ttacaaagac tcctagatgg agagataaaa agctatttgt tctttacttg tgtcctacta
    66001 atcggtattt tcatcaatgc aatctatttt ttacaaatag ttgattatgt ggggaatgtg
    66061 actcgttcgg caatcaccta tttgatgttt ctttggcttg gttctatgct gctctatagt
    66121 gccttgcctt actatatggt tcctatgacg agtttgatgc aagctagcta tggggatgta
    66181 agtttgatga aactctttac tccttatatc ctttatattg tcccttatat ggtgcttgaa
    66241 aaatatgaag ataatgttta agaattttaa caatatttgg ctaaagagaa agatcgtttt
    66301 actacttcgt atagttctga tgatgatttt gataaactat ctattgtcaa cagcggttca
    66361 aaagcaggat gctgttatct ttttcaagag agaattgatt tcaatctttt cctataatga
    66421 ctattctgaa gcgaatttag aaatccccaa actcttgtta aacctttcgc ttttcatggt
    66481 aggatggctc tctgtcattt tacttgaaag tgatttggca gaccattacc atcacttgat
    66541 tcgctatcaa tcaagctcct ttttcgatta tacaaggaaa cgattggttg tcatttctaa
    66601 attttttact caagatttac ttgtctggtt ccttggttta cttccgctag gaattcattt
    66661 caaaacagtc gcacttttct ttttacttgc tcagttaatg atgttgtact tactactgtc
    66721 ttatctgata gcactgatta gtgcgggcgc tggtttttcc ttttttctct attttttagc
    66781 atttgtggga caagaatgga tgatggatca tattgtaaca gtgtatttac tactcttaag
    66841 tttattagtt atgttgattc ttagtcgctt ggaagagaaa tttaagaaag gataaacgat
    66901 gagacttgaa attataaatg gacagaaaat ttatgggaaa agacctattt taaatcagtt
    66961 gaatttggtg tttcaatcag gaaaaattta tggacttaaa ggtgataatg gatctggcaa
    67021 gacggttctt ttaaaggtac ttgctggtta tattaagctt gacaaaggaa aagttcttca
    67081 agacgggaaa gtctacggga taaaaaatca ttatattcag gatgcaggaa ttttaattga
    67141 aaaagtcgag tttttatctc atttatccct gagagaaaat ttggaactgt taaggtattt
    67201 ttcatctaaa gttacggaaa aaagaattgc ctattggatt caatactatg atttacagga
    67261 atttgaagac gttgaatacc ggcatttatc cttgggaaca aagcaaaaaa tggccttgat
    67321 tcaagccttt atttcctctc cttctatact ctttctcgat gaacctatga atgctttgga
    67381 tgagaaaagt gtgaggttaa ccaaacaggt cattttatct tacctgaaaa aagaaaatgg
    67441 tctggttatc ctgacgtcgc acatatcgga agatatttca gacctttgta cagatgtatt
    67501 agttgtcgaa aatggacata tacaatatgt aaaggatata caatcctagg agatggctta
    67561 tggcacatct aaaatcattt attacacgct attccaaggt ttatattggt ttagttctgc
    67621 tgatctggct gtctttcttc tttatccctt gggatagagc gattctgggg gtaaggattg
    67681 acatcttcat catacagaaa gtcttgctag tttttggaat tctgtccatt ttgatggcct
    67741 tgctgtccaa gaaagtcagt ctctttgttt ttggactgat ttgctgtctt tctctttgga
    67801 ttaacttatt tatcacattt gccattttgc caatttttgg caattaaaca gtcataaaag
    67861 tcggagaggt tagcttgaaa actaacctct ttttcctttt caaaatgggg attcttcctt
    67921 gaaaataatc agtaattgtg ctaaaattaa aggaacattc taaaatattc ggaatttaaa
    67981 gtaaggaaaa acatggctaa tattttaaaa acaattatcg aaaatgataa aggagaaatc
    68041 cgtcgtctgg aaaagatggc tgacaaggtt ttcaaatacg aagaccaaat ggctgctttg
    68101 actgacgacc aactaaaagc aaaaacagtt gaatttaagg aacgttatca aaatggagaa
    68161 tcactggatt cattgcttta cgaagcattt gcggttgtcc gtgaaggtgc caaacgtgtc
    68221 ctaggtctct tcccttataa ggttcaggtc atggggggga ttgttcttca ccatggtgac
    68281 gtgccagaga tgcgtacagg ggaagggaaa accttgactg cgaccatgcc ggtatacctc
    68341 aatgcccttt caggtaaagg ggttcacgta gttacggtta atgaatacct gtcagaacgt
    68401 gacgcgactg agatgggtga attgtactct tggcttggtt tgtcagtagg gattaacttg
    68461 gctaccaaat ctccaatgga gaaaaaagaa gcctatgagt gtgatattac ttactcaact
    68521 aactcagaaa tcggatttga ctaccttcgt gacaatatgg tcgttcgcgc tgaaaacatg
    68581 gtacaacgtc cgcttaacta tgccttggtc gatgaggttg actctatctt gattgacgag
    68641 gctcgtacac ctttgattgt atcaggtgcc aatgcggttg aaaccagtca gttgtatcac
    68701 atggcagacc actatgtaaa atctttgaac aaagatgact acatcatcga tgtgcagtct
    68761 aagactattg gtttgtctga ttcagggatt gacagggctg aaagctactt caaacttgaa
    68821 aacctctatg acatcgaaaa cgtggctttg acccacttta tcgataacgc ccttcgtgcc
    68881 aactacatca tgcttctcga tattgactat gtggtgagcg aagagcaaga aatcttgatt
    68941 gtcgaccaat ttacaggtcg taccatggaa ggtcgtcgtt attctgatgg attgcaccaa
    69001 gctattgaag ccaaagaagg tgtgccaatc caggatgaaa ccaagacatc tgcctcaatc
    69061 acgtaccaaa accttttccg tatgtacaaa aaattgtctg gtatgacggg tacaggtaag
    69121 actgaggaag aagaatttcg tgaaatctac aacattcgtg ttattccaat cccaacaaac
    69181 cgtcctgttc aacgtattga ccactcagac cttctttatg caagtatcga atctaagttt
    69241 aaagcggttg tcgaagacgt taaggctcgt taccaaaagg gtcaacctgt cttggttggt
    69301 acagtagcgg ttgaaactag tgactacatt tctaagaaat tggttgcagc tggtgttcct
    69361 cacgaagtct tgaatgccaa aaaccactat agagaagccc aaatcatcat gaatgctggt
    69421 caacgtggtg ccgttaccat cgcaaccaac atggcgggtc gtggtaccga catcaagctt
    69481 ggtgaaggtg ttcgtgaact tggaggactt tgtgttattg gtacagaacg tcatgaaagt
    69541 cgtcgtatcg ataaccagct tcgtggacgt tcaggtcgtc aaggagatcc aggtgagtca
    69601 caattctacc tatctcttga agatgatttg atgaaacgtt ttggttctga acgcttgaag
    69661 ggaatctttg aacgcttgaa catgtctgaa gaggcgattg agtctcgcat gttgacgcgt
    69721 caggttgaag cagcgcaaaa acgtgtcgaa ggaaataact acgatacccg taaacaagtc
    69781 cttcaatacg acgatgtcat gcgtgaacaa cgtgagatta tctatactca acgttatgat
    69841 gtcattactg cagaccgtga cttggcacct gaaattcagg caatgatcaa acgcacgatt
    69901 ggtcgtgtcg ttgacggtca tgcgcgtgct aaacaagatg agaaactaga ggcaattttg
    69961 aacttcgcta agtacaactt gcttcctgaa gattctatta cgatggaaga cttgtcaggc
    70021 ttgtctgata aggccatcaa ggaagagctt ttccaacgtg ccttgaaggt ttacgatagt
    70081 caggtttcaa aactacgcga tgaagaagca gttaaagaat tccaaaaagt tttgattcta
    70141 cgagtggtgg ataacaagtg gacagatcat atcgatgccc ttgatcaatt gcgtaacgcg
    70201 gttggacttc gtggctatgc tcagaacaac cctgttgttg agtatcaggc agaaggtttc
    70261 cgtatgttta atgatatgat tggttcgatt gagtttgatg tgacacgctt gatgatgaaa
    70321 gcacaaattc atgaacaaga aagaccacag gcagaacgtc atatcagtac aacagcgact
    70381 cgcaatatcg ctgctcacca agcaagtatg ccagaagatt tggatttgag ccagattgga
    70441 cgcaatgaac tttgcccatg tggttctggt aagaaattta aaaactgtca cggtaaaaga
    70501 caataaaatg agatagttta gaggcggata tcttgtgaaa agtaaatttt tactgggtat
    70561 ccgtttgctt tataaggaga tgagttatgg tatttacagc aaaaagctct aaaataaata
    70621 tagaagaagt tcgtgccttg tcaaaattag aaggtcaggc tttggagagg aaatcacagc
    70681 gagatcaaga gctagaagcc attatacgtg gagaagacca gcgaattctc ttggtaatcg
    70741 ggccatgctc atctgacaac gaagaagctg tccttgaata cgctaagcgt ttggcagtcc
    70801 tacaagaaga agtggcagat cgtatcttta tggttatgcg tgtttatact gccaaacccc
    70861 gtaccaacgg agatggctat aagggcttga ttcaccagcc taacgcgaca gaagcgccta
    70921 gtcttatcaa tggaatcaaa gccgttcgcc atcttcacta tcgtgtcatc acagaaacag
    70981 ggatgacaac tgctgatgaa atgctttatc ctgaaaacct tccgcttgta gatgatttga
    71041 tttcttacat ggcagttggt gcccgttcag ttgaagacca gcaacaccgc tttgtggcaa
    71101 gtggggcagg attttctact ggttttaaaa atccaacctc tggaaatctc aatgtcatgt
    71161 ttaatgggat ttatgctgct caaaacaaac aaagtttcct tttcttagga aaagaagtag
    71221 aaacaactgg gaacccgctt tcacacgcta ttcttcgtgg tgctcttaat gagtatggaa
    71281 aaaatattcc caactactat tatgacaatt taattgatac cattgcccag tatgagaaaa
    71341 tgggcttgga aaatcctttt atcatcattg ataccaatca tgacaattct ggtaagcagt
    71401 atattgaaca gatccgaatt gtccgccagg ccttgattaa ccgtgcttgg aatgaaaaaa
    71461 ttaagcagtt cgttcgtggt tttatgattg agtcttatct ggaagatggt cgacaaaatg
    71521 agccagaagt atttggtaag tctatcacag acccttgcct gggttgggat aacacagaag
    71581 ctcttgtcag agaaatttac aaaacgttag gagaataaga tggcatttat tgaaaaaggt
    71641 caagaaatcg atatggaagt catcaaggct gaaacccaat tgtctgcgga agccttgaga
    71701 ctcaaggaaa gccgtgacag ggaattggca gatattattt caggggaaga tgaccgtatt
    71761 ctcttggtga ttggtccttg ctcttctgat aatgaagagg cggtcttgga atatgctcgc
    71821 cgtttatccg ccttgcaaaa gaaggtagcg gataagattt tcatggtcat gcgcgtgtat
    71881 actgctaagc ctcgtaccaa tggagacggc tataaaggat tggttcacca gccagatact
    71941 tctaaggctc caagcctgat taacggcttg caggctgtgc gccagttgca ctaccgcgtg
    72001 attacagaga ctggtttgac aacggcagat gagatgcttt atccgtcaaa tctgatcttg
    72061 gtggatgact tggtcagcta ccatgccgtt ggagctcgtt ctgtggaaga ccaagagcac
    72121 cgctttgtgg cttctgggat tgatgcacca gtagggatga aaaatccaac ctcaggaaat
    72181 ttgggtgtta tgtttaacgc catctatgct gctcaaaaca agcaaacctt cctttatcat
    72241 gggcaggaag ttgagacatc aggtaatcct ttggcccatg ttatcctccg tggagcagtc
    72301 aacgagtatg gcaattatat gccgaattac tactatgaaa acctactcca agccattgaa
    72361 cgctatgaaa ccatgggact tgaaaatcct tttatcctca ttgacaccaa ccatgataac
    72421 tcaggcaagc aatatatgga gcagattcga attgttcgcc agaccttgca gaatcgtgat
    72481 tggaatgaga aaattaaaaa gacggttcga ggatttatga ttgaatctta cctagcagat
    72541 ggtcgtcaaa accaaccaga gatctttggt tgctctatta ctgacccttg cctaggttgg
    72601 gaaaatacag aggccttggt agaagagatt tatgttacct tgacaaaata agtgaaaagg
    72661 atggagttgg ggaatctcaa ctccttttga tgagaatgat agttggacac ggaattgaca
    72721 tcgaagaatt ggcttcgata gaaagcgcag ttacacgaca tgaaggattt gctaagcgtg
    72781 tactgaccgc tcaggaaatg gagcgcttca ccagtctcaa aggacgcagg caaatagaat
    72841 atttagctgg tcgctggtcg gctaaggagg ccttttccaa ggctatggga acgggcatta
    72901 gcaagctcgg ttttcaggat ttggaagtct tgaacaatga acgtggggcg ccttatttta
    72961 gtcgggcacc attttcagga aagatttggc tgtctatcag ccacaccgat cagtttgtga
    73021 cagccagtgt cattttggag gaaaatcatg aaagctagtc cacatagacc aaccaaggct
    73081 ctgattcatc tgggagctat tcgacaaaat attcagcaaa tgggggctca tatccctcaa
    73141 ggaacgctca agttggctgt ggttaaggcc aatgcttatg gtcatggagc tgttgccgtt
    73201 gccaaggcaa ttcaagatga tgttgatggc ttttgcgttt ccaatatcga tgaagccatt
    73261 gaactcagac aagctggact cagcaagcca atcctcattt taggagtttc tgaaatcgaa
    73321 gctgttgctc tagctaaaga atatgacttc accttgacag tggctggact ggagtggatt
    73381 caagcactct tagataagga agtggaccta actggattga cagtccacct caagattgat
    73441 tcaggaatgg gacggattgg ttttagagag gccagtgagg ttgagcaggc tcaagatttg
    73501 ctccaacaac acggtgtttg tgttgaagga atctttaccc actttgctac tgctgatgag
    73561 gaatcagatg actattttaa tgcccagtta gaacggttta aaactatttt agctagtatg
    73621 aaggaagttc cagagctggt tcatgctagc aattctgcaa cgactctttg gcatgtagag
    73681 actattttca atgcggttcg tatgggagat gccatgtatg gcctcaatcc aagtggagcg
    73741 gtcttggatt tgccttatga tttgataccg gccttgacct tggagtctgc tctggttcat
    73801 gtcaagacag ttccagctgg agcttgcatg ggctatggag caacttatca agcggatagc
    73861 gagcaagtca tcgcgaccgt gccaatcggg tatgcagatg gatggacaag agacatgcaa
    73921 aatttctctg tcttggtaga tggccaagct tgcccaattg tcggcagggt ttcgatggac
    73981 caaatcacta ttcgattgcc taagccttac ccactcggaa ccaaggtaac cttgattggc
    74041 tccaatgggg ataaggaaat cactgcaact caggtagcga cctaccgcgt aaccattaac
    74101 tatgaggtgg tttgcctcct cagcgaccgt attccgagag aatattatta gaaaagaaag
    74161 gagtggagca tgaatctaca tcaacccttg catgtcttgc ctggtgtggg accaaagtca
    74221 gcagaaaaat acgccaaact aggaattgaa aacttgcaag atctcttgct ctactttcct
    74281 ttccgttatg aagacttcaa aaccaagcag gtgctggagc tggaagacgg tgagaaggca
    74341 gttctttctg gtcaggtagt gactcctgct agtgtccagt attatggttt caagcgcaat
    74401 cgcctgcgtt ttagtctcaa gcagggagag gtcgtttttg cggtgaattt ctttaaccag
    74461 ccctatctgg ctgataaaat agagttggga gcaacccttg ctgtctttgg aaaatgggac
    74521 cgcgctaagg ctagtctgaa tgggatgaag gttctggctc aggtagaaga tgacctccag
    74581 cctgtttatc gtctggctca gggaatcagt caggccagtc tggttaaggt catcaagacg
    74641 gcttttgatc agggactgga cctcttgata gaagaaaatc tgccccagtc tttactagac
    74701 aaatacaaac tcatgtcccg ttgtcaggca gtccgagcta tgcattttcc aaaggatttg
    74761 gcagaataca agcaggctct tcgccgtata aagtttgagg aactctttta tttccaaatg
    74821 cagctgcaga tgctcaagtc tgaaaataga gttcagggaa gtggtctggt tctgaattgg
    74881 tctcaggaaa aagtgacagc agttaaagta agtcttcctt ttgccctgac ccaagctcag
    74941 gaaaagagtt tgcaggaaat tttaactgat atgaagtccg accaccacat gaatcgtctc
    75001 ctacaagggg atgtggggag tggaaaaacg gtagtcgctg gcttggccat gtttgcggca
    75061 gtgacagcag gttatcaggc tgccctaatg gtaccaacag aaatcctcgc agagcaacac
    75121 tttgagagtt tacagaacct ttttcccaat ttgaaactgg ctctcttgac aggttccttg
    75181 aaagctgcag aaaagagaga ggtcttggag accattgcca agggtgaggc tgatttgatt
    75241 ataggaactc acgctctgat acaagatggg gtggagtatg ctcgtcttgg tttgattatt
    75301 atcgatgagc agcaccgttt tggtgtaggg caaaggcgta ttttacggga aaaaggtgac
    75361 aatccagatg tcctcatgat gacggcgact cccattccac ggacgcttgc catcacagcc
    75421 tttggagata tggatgtttc cattatcgac cagatgccag caggtcggaa gcctattgtg
    75481 acgcgctgga tcaaacatga gcaactacct caggtcttga cttggttaga gggggaaatt
    75541 caaaaaggtt cccaagtcta tgtcatctct cctttgattg aagaatcaga agctctagat
    75601 ttgaaaaatg ccattgcctt atcagaggag ttgacgactc attttgcagg caaggcagag
    75661 gtggctcttc tacatggtag gatgaagagt gacgaaaaag accagatcat gcaggatttc
    75721 aaggagagag agacggatat tctggtttcg acgacggtta ttgaggttgg ggtcaacgtt
    75781 cccaatgcga ctgtcatgat tatcatggat gccgatcgct tcggtctcag tcaacttcac
    75841 cagcttagag gtcgtgtcgg tcggggggac aagcagtcct acgctgttct cgttgccaat
    75901 cccaagacgg attctgggaa agaccgcatg cgcatcatga tagaaacgac caatggattt
    75961 gtccttgcgg aggaagattt gaaaatgcgt ggttctggtg agatttttgg aaccagacag
    76021 tcaggacttc cagagttcca agtggctgat attatcgaag attttccgat tttagaagaa
    76081 gcaagaaagg ttgctagcta cattagttct atagaagttt ggcaagaaga tccagagtgg
    76141 cgcatgattg cccttcatct ggaaaagaaa gaacatctgg attaagcttt ctctaaggaa
    76201 aacttaagct agtttttagg tttggctctt atactaaagt catcaaaaag aaacgaggac
    76261 tctcatatga cagtaacgat taaagtaaat taccaaacca ctttccaaaa gaaggaagca
    76321 aaaaactagt ataaacagaa gagagagcga aatgctcttt ttcgtttcta aaactacttt
    76381 cagcccatca tcctaaaagt aaagaatcta aattcacttt ctatttatcc ttctttcttg
    76441 cattgattac atagatatgc tacagttgtg gtaacgatta caaaataaaa ggagcatgct
    76501 atgaaaaatc cagctttgct agaagaaatt aagacctata gaggaaggga tgaggttccg
    76561 gaagactttg atgctttctg ggatggggaa gtgaaaaatg tttccacacc tccatcctac
    76621 cacttggagg aaagagattt ccacattcct caagtcaagt gctatgagtt aacatttgaa
    76681 ggaagcaagg aaggaaaggt ctatgcacgc attgttcttc caaagagtga ggagaaggtt
    76741 ccactaatct tccattttca tggttatatg ggacgtggct gggactgggc cgacatgctg
    76801 ggcttcaccg tagctggtta cggtgttgtt tccatggatg tgcggggcca gtcaggttac
    76861 tcacaagacg gcttgcgttc tcctttagga aataccgtga aggggcatat tatccgtggt
    76921 gctatggaag gtcgggacca cctcttttat aaggatgttt atctggatat ttaccagttg
    76981 gtcgaaattg ttgctagtct gtctcaggtt gatgagaagc gtctttctag ctatggtgcc
    77041 tcacaaggag gggctctagc tctagttgca gcagcgctca atcctcgaat tcagaaaaca
    77101 gttgccattt atcccttctt gtcagacttc agacgggtga ttgagattgg taatactagc
    77161 gaggcttacg acgaactttt ccgttatttc aagtttcacg accccttcca tgaaacagag
    77221 gaggaaatca tggcgaccct tgcctatatc gatgtcaaaa atcttgccca tcgtatccaa
    77281 ggtgaggtta agatgattac gggcttggac gacgatgttt gctatcccat tacccagttt
    77341 gcgatttata atcgtctgac ctgcgataaa acctatcgta tcatgcctga gtatgctcac
    77401 gaagccatga atgtatttgt caatgaccaa gtctacaact ggctctgtgg aagtgagatt
    77461 ccttttaaat atttaaaata aggagtcgac tctaagcaca aaatcttaaa aattacaaac
    77521 acgcatagta tcaggggctt aagaaaactt gatactatgc gttttatcat ggaaatatag
    77581 taaaatgaaa caagaacagg acaaattgat caggacagtc aaatcgattt ctaacaatgt
    77641 tttagaagca aatgtgtact attctagttt caatctatta tatttataga attttttgtt
    77701 gctagatttg tcaaattgct taaaataatt tttttcagaa agcaaaagcc gatacctatc
    77761 gagtagggta gttcttgcta tcgtcaggct tgtctgtagg tgttaatact tttcaaaaat
    77821 ctctttaaac cacgtcagct tcgccttgcc gtatatatgt t
//
LOCUS       DAVMCG010000005        74000 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVMCG010000005 DAVMCG010000000
VERSION     DAVMCG010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.005"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            189..686
                     /locus_tag="VYP66_000399"
     CDS             189..686
                     /locus_tag="VYP66_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1850009.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            686..2341
                     /gene="dnaX"
                     /locus_tag="VYP66_000400"
     CDS             686..2341
                     /gene="dnaX"
                     /locus_tag="VYP66_000400"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1850010.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYTPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQIEKEVEESLIPEGFEFLADKVKVEED"
     gene            2369..2563
                     /locus_tag="VYP66_000401"
     CDS             2369..2563
                     /locus_tag="VYP66_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1850011.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2713..3483
                     /gene="sufC"
                     /locus_tag="VYP66_000402"
     CDS             2713..3483
                     /gene="sufC"
                     /locus_tag="VYP66_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1850012.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3511..4773
                     /gene="sufD"
                     /locus_tag="VYP66_000403"
     CDS             3511..4773
                     /gene="sufD"
                     /locus_tag="VYP66_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1850013.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLLGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4784..6010
                     /locus_tag="VYP66_000404"
     CDS             4784..6010
                     /locus_tag="VYP66_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1850014.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINACSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5997..6437
                     /locus_tag="VYP66_000405"
     CDS             5997..6437
                     /locus_tag="VYP66_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1850015.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6487..7899
                     /gene="sufB"
                     /locus_tag="VYP66_000406"
     CDS             6487..7899
                     /gene="sufB"
                     /locus_tag="VYP66_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1850016.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKDGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8098..9339)
                     /locus_tag="VYP66_000407"
     CDS             complement(8098..9339)
                     /locus_tag="VYP66_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1850017.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9442..10551
                     /locus_tag="VYP66_000408"
     CDS             9442..10551
                     /locus_tag="VYP66_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1850018.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11227..11574
                     /gene="ssrA"
                     /locus_tag="VYP66_000409"
     tmRNA           11227..11574
                     /gene="ssrA"
                     /locus_tag="VYP66_000409"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11818..12594)
                     /locus_tag="VYP66_000410"
     CDS             complement(11818..12594)
                     /locus_tag="VYP66_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HEV1850019.1"
                     /translation="MNATDIKNTYLNYIKENAVFNDVTDTHTEVITPFIDPLGEAIGF
                     SIKSNGKHLTVTDDGYTIWNLSINNIDVTKKGRRQDIFNSLLHFNGFDLHDGAIERTT
                     GKEHLGQVIHDMTQLLMNVYDFIQLTPNNIKSQFLDDVKSYFMKNEHYTVFPAFSIAG
                     KSRLEHRFNFVFMSKGISKIARVHNNITKQQVDTILASWLDTSEYRRKEYGDTEQLYI
                     IVSDEGYNNIKDDHQIALQEYGINILNFSDKEQLEIQLGK"
     gene            complement(12621..13091)
                     /locus_tag="VYP66_000411"
     CDS             complement(12621..13091)
                     /locus_tag="VYP66_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850020.1"
                     /translation="MKELLLTDSEAKALIKIIKAIANKHNRTLTNRSSGTINLVGKHD
                     TRFILNYFYSTTSKVFHLRETQHNYTLLRINLNNKFHKNANGEKVWGNRVNIFSEEEY
                     YQKGDETTHYKAYPLPYEDILNTDDFLDMLDNLLDYTNVNNPENIAINIQEDLL"
     gene            complement(13146..13610)
                     /locus_tag="VYP66_000412"
     CDS             complement(13146..13610)
                     /locus_tag="VYP66_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HEV1850021.1"
                     /translation="MSKVVKVTGAEVVISHNEEYLKVNPSELNFVPKLGDEVEVHKVD
                     GEIIVIKVKDKKDDKININIVNENNAMQNQSQVVHTQEIATGVHYVNKWVYVILALFL
                     GGLGIHHFYAGYNGKGFLFLILSLTGIPAIIALFQGIIALFKKPDVYGRIAV"
     gene            complement(13966..14053)
                     /locus_tag="VYP66_000413"
     tRNA            complement(13966..14053)
                     /locus_tag="VYP66_000413"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14017..14019),aa:Ser,seq:gga)
     gene            14215..14955
                     /locus_tag="VYP66_000414"
     CDS             14215..14955
                     /locus_tag="VYP66_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1850022.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            14952..15863
                     /gene="pfkB"
                     /locus_tag="VYP66_000415"
     CDS             14952..15863
                     /gene="pfkB"
                     /locus_tag="VYP66_000415"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1850023.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVKLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            15860..17812
                     /locus_tag="VYP66_000416"
     CDS             15860..17812
                     /locus_tag="VYP66_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1850024.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLTGHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALTELSQYLMKDGFADKLRQATSADQVVELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAVDKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDAEVYRAANGAK
                     AATVSNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            17976..20201
                     /locus_tag="VYP66_000417"
     CDS             17976..20201
                     /locus_tag="VYP66_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1850025.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(20246..20674)
                     /locus_tag="VYP66_000418"
     CDS             complement(20246..20674)
                     /locus_tag="VYP66_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850026.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            20837..22921
                     /locus_tag="VYP66_000419"
     CDS             20837..22921
                     /locus_tag="VYP66_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1850027.1"
                     /translation="MFEIRNLSLSFAGRRLLEPTDLIFERGKVYTIYGKSGVGKSSLL
                     NKIGLLSATDPSVSYFFDGKEIDIENKKSVSVFIAEEVAFVFQGRNLINDLTVFENLR
                     LALNFYDLSPDEIESKIDTVLADLQISSLKHAYPEDLSGGEEQRVAIARALVTGKTLI
                     LADEPTSSLDKENREKISALLIDLAHKYHKIVLIVSHDEAMIAIGDVQLHFKDHKLVG
                     NCLILNSDEGIKDSKKWSSCLSSSHTKLSVLKHRRPFLPRLLAFFISLVVAIAVTSIN
                     FQSLFADKYHQLVNNSLENGFLVINDSLHLQTTKVLDDFLSFDKEEITSISTSQNIQT
                     VNPYIEFLSLGMTFDNSKDYSQLQKNFQPTLTIDGQTRSLTRNFSIQPLYQTNTTQRQ
                     IEYFDRSNEKGIYLSEQFISDEKLPNIVSGTTVTLTFYIPISLYESSIEKEGNILKGD
                     GGLFVKVDKTYPVLGIVKKSYPFEYSPYGNTLFMNIAEMEELQNEAIQQHPMTKMALD
                     GFPLKSWMPSAIHVLLKDSGAIPEELSRIRAISSQITILSSYENYEEFNKGLTYIRQF
                     LMLLSLVLLILVIAVLSFVFFLLNRPRRFEVGILKSLGYSTQNIVWLFLKELIGYGKT
                     ISILASCLLVILSILAMQVLKLEISDVFKFYLTSVFTLIGLSVSVLIISGLLPIYTTC
                     RQTVVDTIRKNG"
     gene            22931..23308
                     /locus_tag="VYP66_000420"
     CDS             22931..23308
                     /locus_tag="VYP66_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850028.1"
                     /translation="MKHKIMKKIIVVVFAIPWLTFLSQVHADYVSKSSSLDGYSLVGL
                     NVLNVTFNASGYSDTYSGSVSNMYFTDWAWFPNTISNRSTWKSSIPYGQRANGTVHIG
                     VGVNSPWGAVNLWGGQNYFSLDF"
     gene            23468..24610
                     /locus_tag="VYP66_000421"
     CDS             23468..24610
                     /locus_tag="VYP66_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1850029.1"
                     /translation="MIYFDNSATTSPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            24619..25833
                     /gene="thiI"
                     /locus_tag="VYP66_000422"
     CDS             24619..25833
                     /gene="thiI"
                     /locus_tag="VYP66_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1850030.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            25968..26781
                     /locus_tag="VYP66_000423"
                     /pseudo
     CDS             25968..26781
                     /locus_tag="VYP66_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            26803..27138
                     /locus_tag="VYP66_000424"
     CDS             26803..27138
                     /locus_tag="VYP66_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HEV1850031.1"
                     /translation="MHIEHLSHWSGHPNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGRVQFFTLSSVDSESWLATWKNAHDQAEMHRAYERYVIEEAILLS
                     STRQVSLMA"
     gene            27135..27542
                     /locus_tag="VYP66_000425"
     CDS             27135..27542
                     /locus_tag="VYP66_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1850032.1"
                     /translation="MMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYY
                     NDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQK
                     QIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            27555..28721
                     /locus_tag="VYP66_000426"
     CDS             27555..28721
                     /locus_tag="VYP66_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1850033.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(29212..30882)
                     /locus_tag="VYP66_000427"
     CDS             complement(29212..30882)
                     /locus_tag="VYP66_000427"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1850034.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVDAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWGKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            31112..31801
                     /gene="coaB"
                     /locus_tag="VYP66_000428"
     CDS             31112..31801
                     /gene="coaB"
                     /locus_tag="VYP66_000428"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1850035.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDILIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            31813..32364
                     /gene="coaC"
                     /locus_tag="VYP66_000429"
     CDS             31813..32364
                     /gene="coaC"
                     /locus_tag="VYP66_000429"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1850036.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            32348..32911
                     /locus_tag="VYP66_000430"
     CDS             32348..32911
                     /locus_tag="VYP66_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1850037.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGITLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            33193..33720
                     /locus_tag="VYP66_000431"
     CDS             33193..33720
                     /locus_tag="VYP66_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1850038.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            33732..34247
                     /locus_tag="VYP66_000432"
     CDS             33732..34247
                     /locus_tag="VYP66_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1850039.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(34244..34711)
                     /locus_tag="VYP66_000433"
     CDS             complement(34244..34711)
                     /locus_tag="VYP66_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1850040.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(34784..35272)
                     /locus_tag="VYP66_000434"
     CDS             complement(34784..35272)
                     /locus_tag="VYP66_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850041.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            complement(35238..35801)
                     /locus_tag="VYP66_000435"
     CDS             complement(35238..35801)
                     /locus_tag="VYP66_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850042.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            complement(35811..37799)
                     /gene="uvrB"
                     /locus_tag="VYP66_000436"
     CDS             complement(35811..37799)
                     /gene="uvrB"
                     /locus_tag="VYP66_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1850043.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(37876..38829)
                     /locus_tag="VYP66_000437"
     CDS             complement(37876..38829)
                     /locus_tag="VYP66_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1850044.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            38999..41164
                     /locus_tag="VYP66_000438"
     CDS             38999..41164
                     /locus_tag="VYP66_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1850045.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            41164..41904
                     /locus_tag="VYP66_000439"
     CDS             41164..41904
                     /locus_tag="VYP66_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1850046.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            42053..43540
                     /locus_tag="VYP66_000440"
     CDS             42053..43540
                     /locus_tag="VYP66_000440"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1850047.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGTSPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLKKFGAKWTWQPDITYRQDGRLE"
     gene            complement(43586..44863)
                     /gene="ftsY"
                     /locus_tag="VYP66_000441"
     CDS             complement(43586..44863)
                     /gene="ftsY"
                     /locus_tag="VYP66_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1850048.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEIS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(44867..45685)
                     /locus_tag="VYP66_000442"
     CDS             complement(44867..45685)
                     /locus_tag="VYP66_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1850049.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(45685..46479)
                     /locus_tag="VYP66_000443"
     CDS             complement(45685..46479)
                     /locus_tag="VYP66_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1850050.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            complement(46476..50015)
                     /gene="smc"
                     /locus_tag="VYP66_000444"
     CDS             complement(46476..50015)
                     /gene="smc"
                     /locus_tag="VYP66_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1850051.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKYDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKKKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRVGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMAALTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQESLATIASEKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEEVAQARLLKTELQGQKRYEVADIERLGKELDNLNIEQEEIQRMLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQNQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNLEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(50006..50704)
                     /locus_tag="VYP66_000445"
     CDS             complement(50006..50704)
                     /locus_tag="VYP66_000445"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1850052.1"
                     /translation="MKELQTVLKNHFEIEFADKKLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(50887..50958)
                     /locus_tag="VYP66_000446"
     tRNA            complement(50887..50958)
                     /locus_tag="VYP66_000446"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50923..50925),aa:Arg,seq:ccg)
     gene            complement(51022..52008)
                     /locus_tag="VYP66_000447"
     CDS             complement(51022..52008)
                     /locus_tag="VYP66_000447"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1850053.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHAESVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(52183..53499)
                     /locus_tag="VYP66_000448"
     CDS             complement(52183..53499)
                     /locus_tag="VYP66_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1850054.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IVVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKITRRNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEIGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(53486..55417)
                     /locus_tag="VYP66_000449"
     CDS             complement(53486..55417)
                     /locus_tag="VYP66_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1850055.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYISPEEVETDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            complement(55581..55742)
                     /locus_tag="VYP66_000450"
     CDS             complement(55581..55742)
                     /locus_tag="VYP66_000450"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850056.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQVEYY"
     gene            complement(56003..56146)
                     /locus_tag="VYP66_000451"
     CDS             complement(56003..56146)
                     /locus_tag="VYP66_000451"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850057.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            complement(56365..56724)
                     /gene="leuD"
                     /locus_tag="VYP66_000452"
     CDS             complement(56365..56724)
                     /gene="leuD"
                     /locus_tag="VYP66_000452"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1850058.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            complement(56728..56997)
                     /locus_tag="VYP66_000453"
     CDS             complement(56728..56997)
                     /locus_tag="VYP66_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1850059.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            complement(56994..58031)
                     /gene="leuB"
                     /locus_tag="VYP66_000454"
                     /pseudo
     CDS             complement(56994..58031)
                     /gene="leuB"
                     /locus_tag="VYP66_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            complement(58043..59137)
                     /locus_tag="VYP66_000455"
     CDS             complement(58043..59137)
                     /locus_tag="VYP66_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1850060.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            complement(59156..59812)
                     /locus_tag="VYP66_000456"
     CDS             complement(59156..59812)
                     /locus_tag="VYP66_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1850061.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            complement(59856..60488)
                     /locus_tag="VYP66_000457"
     CDS             complement(59856..60488)
                     /locus_tag="VYP66_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1850062.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AAELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            complement(60581..60940)
                     /locus_tag="VYP66_000458"
     CDS             complement(60581..60940)
                     /locus_tag="VYP66_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1850063.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            complement(61161..63248)
                     /gene="topA"
                     /locus_tag="VYP66_000459"
     CDS             complement(61161..63248)
                     /gene="topA"
                     /locus_tag="VYP66_000459"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1850064.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNKAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            complement(63415..64458)
                     /locus_tag="VYP66_000460"
     CDS             complement(63415..64458)
                     /locus_tag="VYP66_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1850065.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            complement(65342..66190)
                     /gene="dprA"
                     /locus_tag="VYP66_000461"
     CDS             complement(65342..66190)
                     /gene="dprA"
                     /locus_tag="VYP66_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1850066.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(66276..66965)
                     /locus_tag="VYP66_000462"
     CDS             complement(66276..66965)
                     /locus_tag="VYP66_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1850067.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(66977..67855)
                     /locus_tag="VYP66_000463"
     CDS             complement(66977..67855)
                     /locus_tag="VYP66_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1850068.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(67845..68714)
                     /gene="licA"
                     /locus_tag="VYP66_000464"
     CDS             complement(67845..68714)
                     /gene="licA"
                     /locus_tag="VYP66_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1850069.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            complement(68731..69753)
                     /locus_tag="VYP66_000465"
     CDS             complement(68731..69753)
                     /locus_tag="VYP66_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1850070.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(69758..70465)
                     /locus_tag="VYP66_000466"
     CDS             complement(69758..70465)
                     /locus_tag="VYP66_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1850071.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            70801..72288
                     /gene="tacF"
                     /locus_tag="VYP66_000467"
     CDS             70801..72288
                     /gene="tacF"
                     /locus_tag="VYP66_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1850072.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            72298..73101
                     /locus_tag="VYP66_000468"
     CDS             72298..73101
                     /locus_tag="VYP66_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1850073.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLTFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            73103..73912
                     /locus_tag="VYP66_000469"
     CDS             73103..73912
                     /locus_tag="VYP66_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1850074.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT        22001 a        15076 c        14073 g        22850 t
ORIGIN      
        1 tctttctaat gagttgtttg atcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaaatag gctccataat atccataggg gatttaccca ctacaaatat tatagagccc
      121 aaaatccttt gtttactaaa caagggattt ttcttttgtc tctgctcctt ttttgatata
      181 atagttctat gttaaaatca gaaaaacaat cacgttatca aatgttaaat gaagaattgt
      241 ccttcctatt ggaaggcgaa accaatgttt tggctaatct ttccaacgcc agtgctctca
      301 taaaatcacg ttttcctaat accgtatttg caggctttta tttgttcgat ggaaaggaat
      361 tggttttagg tcccttccaa ggaggtgttt cctgcatccg tattgcacta ggcaagggtg
      421 tttgtggtga ggcagctcac tttcaggaaa ctgttattgt tggagatgtg acgacctatc
      481 tcaactatat ttcttgtgat agtctagcta aaagtgaaat tgtggtgccg atgatgaaga
      541 atggtcagtt acttggagtt ctggatctgg attcttcaga gattgaggat tacgatgcta
      601 tggatcgaga ttatttggaa caatttgtcg ctattttgct tgaaaagaca acatgggact
      661 ttacgatgtt tgaggaaaaa tcttaatgta tcaagcactt tatcgaaaat atagaagtca
      721 aaacttctcc cagttagttg gtcaagaagt tgtggctaag actcttaaac aagcggtgga
      781 gcaagagaaa ataagtcacg cttatctttt ttctggtcct cgtggaacgg gaaaaaccag
      841 tgttgctaaa atctttgcca aggctatgaa ctgtcccaat caagtgggtg gcgaaccttg
      901 caataactgc tatatttgtc aagcagtgac ggacggtagt ttagaagatg tcattgaaat
      961 ggatgcagct tctaataatg gggtagatga aattcgcgaa attcgtgata aatctaccta
     1021 tacgcctagc cttgctcgtt ataaggttta tatcatagat gaggttcaca tgctgtctac
     1081 aggggctttt aatgccctcc taaagacgct ggaagaacca acacagaatg tagtctttat
     1141 tttggccact actgaattgc acaagattcc tgctactatt ctatcccgtg tgcaacgttt
     1201 tgagtttaaa tcaattaaga cacaggatat taaggaacat attcactata tcttagaaaa
     1261 agaaaatatc agttctgaac cagaggctgt ggaaatcatt gccagacggg cggaaggtgg
     1321 aatgcgggac gccttgtcta ttttggatca agccctgagt ttgacacagg gaaatgagct
     1381 gacgactgct atctctgaag aaattactgg caccattagc ctatcagcct tggatgatta
     1441 tgtggcggcc ttgtctcaac aggatgttcc caaagctttg tcttgcttga atcttctttt
     1501 tgacaatggt aagagcatga ctcgttttgt gaccgatctt ttgcactatt taagagactt
     1561 gttaattgtt caaacagggg gagaaaatac tcatcatagt tcagtctttg tagaaaattt
     1621 ggcacttcct caaaaaaatc tgtttgaaat gattcgctta gcaacagtga gtttagcaga
     1681 tattaagtct agtttgcagc ccaagattta tgctgaaatg atgaccgtcc gtttggcgga
     1741 aatcaagccc gaaccagctc tatcaggagc ggttgaaaat gaaattgcta cgctgagaca
     1801 ggaagttgcc cgtctcaaac aagagctttc taatgtaggt gcggttccta aacaagttgc
     1861 accagctcct agtcgaccag ctacgggcaa aacagtctat cgtgtcgatc gcaataaagt
     1921 gcaatctatc ttacaagagg ccgtcgaaaa tcctgattta gcacgtcaaa atctaattcg
     1981 tttgcagaat gcctggggag aggtaattga aagtctaggt gggccggaca aggctctgct
     2041 agttggttct caaccggttg ctgccaatga acaccatgct attcttgctt ttgagtctaa
     2101 cttcaatgct ggtcaaacta tgaaacgaga caatctcaat accatgtttg gtaatatcct
     2161 cagtcaggcg gcaggttttt cacctgagat tttagctatt tccatggagg aatggaaaga
     2221 agttcgcgca gccttttcag ccaaagccaa atcttctcaa attgaaaaag aagtagaaga
     2281 aagcctgatt ccagaaggat ttgaattttt ggctgataaa gtgaaggtag aggaagacta
     2341 aagaaagatt tcatgataca ataagtttat gaataaacaa caatttatta ttatggcgct
     2401 gtttacagct gctgagacct attttttcaa tgaagcctgg atgactggtc gctatattat
     2461 ggcagccttt tgggcaattt tactctttag aaatttccga gtcagttatg tgatgggcaa
     2521 aatcgttgat gtcatcgatc agcattttaa taggaaagac tagccctcag cttccagaca
     2581 aaatcaaagc cttttaggct tttttttgtt atactagaaa agtatattta tagaattttt
     2641 gctctatttc tggggaaatc agacgttttt ctagtaagta ctgtaaaagt tttgaaaaag
     2701 aaaggaacta tcatgtcagt attagagatc aaagatcttc acgttgagat tgaaggaaaa
     2761 gaaattttaa aaggggttaa cctgaccctg aaaacaggag aaattgccgc tatcatggga
     2821 ccaaatggta caggtaaatc gactctttct gccgctatca tgggaaatcc aaactatgaa
     2881 gtaactaaag gtgaagtttt gtttgatggc gtaaacatcc ttgagttgga agtggatgag
     2941 cgtgcgcgta tgggactttt ccttgctatg caatacccat cagaaatccc tggaattacc
     3001 aatgctgagt ttcttcgtgc cgctatgaat gcgggtaaag aagatgatga gaagatttca
     3061 gttcgtgagt ttattactaa gctagatgaa aaaatggaat tgctcaacat gaaagaagaa
     3121 atggcagagc gttacctcaa cgaaggcttc tctggtggtg agaaaaaacg caatgaaatt
     3181 cttcaacttt tgatgttgga gccaacattt gctcttttgg acgagattga ctcaggtctt
     3241 gatattgacg ctcttaaagt tgtgtctaaa ggtgtcaatg ccatgcgtgg tgaaggtttt
     3301 ggtgctatga tcatcactca ctaccaacgt cttttgaact atatcacacc tgatgtggta
     3361 cacgtgatga tggaaggtcg tgttgtcctt tctggtggtc cagaattggc tgcgcgtttg
     3421 gaacgtgaag gatacgcaaa actagctgaa gaacttggct acgactacaa ggaagaattg
     3481 taattccctc gtatctttta ggagaagtaa atgactagag aaaatattaa acttttttca
     3541 gaaatgcacg ctgaaccaag ctggttggct gatctccgtc aaaaagcttt tgacaagatt
     3601 gagactttgg aattaccagt tattgagcgt gtcaaattcc accgttggaa tctgggtgat
     3661 ggaacgatta cagaaaatga gccatcagca aatgttccag atttcacagc tttagatcat
     3721 cacttgaagt tggtgcaagt aggaactcaa actgttttcg aacaaactcc agttgagtta
     3781 gctgaacagg gtgttgtctt cacagacttt cactcagctt tagaagaaat tccagagctg
     3841 atcgaagaat tcttcatgtc atctgttaag tatgatgatg acaagttggc ggcttaccac
     3901 acagcttact ttaacagtgg tgctgtactc tatattccag ataacgtaga aattacagag
     3961 ccaattgaag gaattttcta ccaagatagc gatagcaatg tgccgtttaa caagcatatt
     4021 atgattatcg ctggtaaaaa ttctaagatt agttatctgg agcgtttaga gtcacgcggt
     4081 gaaggaagtg acaaagcaac tgccaatatc acagtggaag tgattgcacg ttctggtgcg
     4141 caagtcaagt ttgctgctat cgaccgtcta ggtgaaaacg tcactgccta cattagccgt
     4201 cgtggtaaat taggcaacga tgcaagtatt gactgggcta tcggtgtcat gaacgaagga
     4261 aatgtcgttg ctgattttga tagtgacttg cttggaaatg gtagccatgc ggacctcaag
     4321 gtagtagcac tttcaagtgg tcgtcaggtg caagggattg atactcgcgt gactaactat
     4381 ggttgcaact ctatcggaaa tatcctacaa catggggtta tccttgaaaa agcaactttg
     4441 actttcaatg gtatcggcca catcatcaag ggtgctaagg gagcagatgc ccaacaagag
     4501 agccgtgttc tcatgctttc agaccaagcg cgttcagatg ctaacccaat tcttttgatt
     4561 gatgaaaatg atgtcactgc aggacacgca gcgtctatcg gacaagttga tccagaagac
     4621 atgtattacc tcatgagtcg tggattggat aaggcaactg cagagcgttt ggttgttcgt
     4681 ggtttccttg gatctgttat cgtggagatt ccagtcaagg aagttcgtga tgaaatgatt
     4741 gcaactatcg aagagaaatt gtcaaaacgc taaggggaag cctatgttag atgtagaagc
     4801 gattcgcaag gattttccaa ttttagatca gattgtcaat gatgaacctc tggtctatct
     4861 ggacaatgct gcgacgacac aaaaaccact agtagttctg aaagctatta acagctacta
     4921 tgaacaggac aatgccaatg ttcaccgtgg tgtccatacc ttagcggaac gagcgacagc
     4981 ttcttatgaa gctgctcgtg aaaccattcg taagtttatt aatgcatgct ctacaaagga
     5041 agttctcttt accagaggaa cgacaaccag ccttaactgg gtggcacgct ttgctgagga
     5101 aattctcact gagggagacc aggtcttgat ttcagtaatg gaacaccatt ctaatatcat
     5161 tccatggcag gaagcttgtc gaaagactgg agcagagctt gtctatgtct atcttaaaga
     5221 cggtgccttg gatatggagg atttgcgagc taaattgact gataaggtta aatttgtttc
     5281 cctagctcat gcctccaatg ttcttggtgt ggtcaatccg attaaggaaa tcactcaatt
     5341 agcccaccaa gttggggcaa tcatggtagt ggatggtgct caatctacac ctcatatgaa
     5401 gattgatgtc caggacttgg atctggactt tttcgccttt tcgggtcaca agatggctgg
     5461 tccgactggt atcggtgtcc tttacggcaa agaaaagtat cttgagcaaa tgtctccagt
     5521 agaatttggc ggcgagatga ttgattttgt ctacgagcaa tccgctagtt ggaaggaatt
     5581 gccttggaaa tttgaggctg gaacgccaaa tatggcagga gctattggac ttgcgactgc
     5641 agttgattat ctggaaaaga ttggtatgga tgccgttgaa gctcatgaac aggaattgat
     5701 tgcgtacgtc tatccaaaac tgcaggcaat tgagggattg accatttacg gttctcagga
     5761 tttggctcaa cgttcgggtg ttattgcctt taacctaggt gatctccatc ctcacgatct
     5821 tgcgacggct ctggattatg aaggagtggc tgttcgtgct ggtcaccatt gtgcgcaacc
     5881 cttgcttcag tatttggaag tcccagcatc agctcgtgca agtttttata tctataatac
     5941 caaggcagat tgcgacaaac tagtcgatgc cctacaaaag acaaaggagt ttttcaatgg
     6001 cactttctaa actagatagc ctttatatgg cagtggtagc agaccattcg aaaaatccac
     6061 atcaccaagg gaagttagaa gacgctgagc aaatcagtct caacaatccg acttgtgggg
     6121 atgtcatcaa cctctctgtc aagtttgatg cagaggaccg tttggaagat attgcttttc
     6181 taaattcagg atgcacgatt tcaactgctt ctgctagtat gatgacagat gccgttttag
     6241 gaaaaaccaa acaagaaatt ttagaactgg cgactatttt ttctgaaatg gttcaagggc
     6301 aaaaagatga gcgtcaagac caacttggag acgcggcatt cttgtcaggt gttgccaaat
     6361 tccctcaaag aatcaagtgt gcaaccctag cttggaatgc ccttaagaaa acaattgaaa
     6421 atcaagaaaa acagtaagac aagtttcttt tgtcttatga attattagaa atgaagaaag
     6481 gatattatgg ctgaagaaag agtagaacca aaaccaattg accttggtga atataaattt
     6541 ggtttccatg acgatgtaga gcctgtctta tcgacaggaa aaggactcaa cgaaggtgtt
     6601 attcgtgaat tatctgctgc taagggtgag cctgagtgga tgttggagtt ccgtttgaag
     6661 tcttatgaaa ccttcaaaaa aatgcccatg caaacttggg gagcagactt gtcagagatt
     6721 gactttgatg acttaatcta ctaccaaaaa ccatctgaca aaccagcccg ttcttgggat
     6781 gatgtacctg aaaagattaa agaaaccttt gaacgtatcg ggattccaga agctgaacgt
     6841 gcttatttag caggggcttc tgcccagtac gagtcagaag tggtttacca caacatgaag
     6901 gaagagttcc aaaaattagg tattatcttt acagatacag attccgcact caaggaatac
     6961 ccagacttat ttaaacaata ctttgcgaag ttggtaccgc cgacagataa caagttggca
     7021 gccctcaact cagcagtatg gtcgggtgga acttttatct acgtgccaaa aggtgtcaag
     7081 gtagatattc cacttcaaac ttatttccgt atcaataacg aaaatatagg tcagttcgaa
     7141 cgtaccttga ttatcgttga tgagggagca agcgtccact acgtagaagg atgtacagca
     7201 ccaacatatt caagcaatag cttgcacgct gccattgtag aaatttttgc tttggacgga
     7261 gcttatatgc gttatacaac tatccaaaac tggtctgata acgtctataa cttggtaaca
     7321 aagcgtgcta aggctcaaaa ggatgccact gttgagtgga ttgatggaaa cttgggtgcc
     7381 aaaacgacta tgaaatatcc atctgtttat cttgatggag aaggagcgcg tggtaccatg
     7441 ctctctatcg cctttgctaa tgcagggcaa caccaagaca cgggtgctaa gatgattcac
     7501 aatgctccac ataccagctc gtctattgtg tctaaatcca tcgctaaaga tggaggaaag
     7561 gttgactacc gtggacaagt cacctttaac aagaactcta agaaatctgt ttcccatatt
     7621 gaatgtgata ccattatcat ggatgacttg tcagcatcag atactattcc atttaatgaa
     7681 attcacaact cgcaagtggc tttggaacac gaagccaaag tatctaagat ttcagaagag
     7741 caattgtatt atctcatgag ccgtggattg tcagaatctg aggcaactga aatgattgtc
     7801 atgggatttg tagaaccctt tacaaaagaa cttccaatgg aatacgcagt tgagctgaac
     7861 cgcttgatta gctatgaaat ggagggatca gttggataaa atttgatttt atactcttcg
     7921 aaaatctctt caaaccacgt cagcatcgcc ttaccgtatg tatggttact gacttcgtca
     7981 gtttcatcta caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgt
     8041 tctttgattt tgaagatgaa cttgtatcaa aaaatcgcgg tttaaaatcg cgatttttta
     8101 taatttctcg ttaacaaagc ggacaaactg attccaccaa acttttaaga agaaggcttt
     8161 ttcaattttc ttgtctgcta ccatttcgaa actagggcgc tctgtggtga tgtaaccttg
     8221 accaatcaag tccttgtctt cataagtcaa atggccaacc actgttccag cttcaagtgg
     8281 tgctgggatt gctttggaat caggtgtgaa ttgaacagat tgggaagatt gattcccaac
     8341 acgttctatt agatagatat cctctggagc cactgcagtt actgtatctt cttttccatc
     8401 ttgtacaggg gttttgctat cttgataggc atcgccttgt tgaacgattt tgcgaagtgt
     8461 aaatgtagaa gaaatataat ccattaggga agatgtagct gtaaatcgag cgtaaggatt
     8521 attgtcttga tgatctgcat ttaaaacaac tgtgatgact ctcatgcctt tttcgacagt
     8581 agtaccaaca aaagactctc cagccttatc tgttgttcct gtttttagcc catcaaaacc
     8641 accacggtaa gcaggcatac cttctaacat gtagttggtt gaagtgattg tcatcccagc
     8701 aaaagtagaa gaaggttttt tggtgatttc taagacttgt gggtattttt tgatgaggtt
     8761 gcgagcaacg atagcgacat cataagcact aagcttattt tcctcatctt ttttagaacc
     8821 tgggtaaatg ttatccccta gagtttcatt gttaagacct gtcgtattga caacagtggc
     8881 atcctgaatt ccccattcca agagttttgc ccgcatcata tcgacgaaat ctttttctga
     8941 gccagcaatt ttctcagcta gggcaatagc ggcgctgttg gcactagata ccagagttgc
     9001 ttcaagcaac tcttcgacag tataattacg ggcctccata ggaatattac tggcttcaga
     9061 atttgtcgtc aattgataag gataatcaga aatatctaca ggagtggaga gggtaatact
     9121 tccgttttcc aaagcttcat agaccagata aacagtaatc aattttgtta tggaagcaat
     9181 ttcgacaggt tgcgttgcat ccttctcata gagaatttta ccagtatttg cctcaacagc
     9241 aatcgcatgt ttagcggcaa tggtaaaatc ttgagcaaca gcagtagaag caccccctaa
     9301 aagagagaca gttaacaaag ttaaaaatat ttttttcata gtagtcttat tctatcataa
     9361 agaaaaaaaa tattcttgct ttaataattc atctgttaag ctttttgaaa atatggtaaa
     9421 ataaagtgag ggaggtaact catgtttcgt agaaataaat tatttttttg gaccacagaa
     9481 attttactct taaccatcat cttttaccta tggagacaga tgggatcttt gattaaccct
     9541 tttgttagcg tgcttaatac aattatgatt ccatttttat tagggggctt tctttattat
     9601 ttgacaaacc ctattgttac tttcttaaat aaagtctgta aactcaatcg tttgcttggt
     9661 attttaatta ccttgtgtac tttggtctgg ggaatggtca taggtgttgt ctatctctta
     9721 cctattttga ttaatcagtt atctagtttg attatatcta gtcaaactat ttatagtcga
     9781 gtacaagact taatcataga cttatctaat tatcctgcgc tccagaattt ggatgtagaa
     9841 gctacaattc agcagttaaa cttatcctat gttgatattc ttcaaaatat cctaaatagc
     9901 gtatcaaata gtgtggggag cgtcttgtca gctcttatca gtactgtttt gattttgatt
     9961 atgactccag tttttttggt ttatttctta ttagatggac ataaattctt gcccatgctt
    10021 gaaagaacga ttctaaagag ggatcgcttg catattgcag gcttattaaa gaatttaaat
    10081 gcgacgattg ctcgctatat tagtggagtt tcgattgacg caatcattat aggttgtttg
    10141 gcttatattg gctatagtat tattggttta aaatatgctt tagtttttgc cattttttct
    10201 ggtgtagcca atttaattcc ttatgtgggg ccaagtattg gtttgattcc tatgatcatc
    10261 gcaaatatat tcactgatcc ccatagactg ctgattgcag tgatttatat gcttgttgtt
    10321 cagcaggtag atggcaatat cttatatcct cgaattgtag gaagtgttat gaaggttcat
    10381 ccaatcacga ttttagtttt acttttgttg tcaagcaata tctatggtgt agttggaatg
    10441 attgtcgcag tgccaaccta ttctatcttg aaagaaattt ctaagttctt atcccgtttg
    10501 tatgaaaatc ataaaataat gaaagaacga gaaagagaat tagctaagta aaagtcagga
    10561 gaaccctgat ttttctttac tggaagtggc ctttagatta gaagactgaa aataagttaa
    10621 agtcttaaac taattttcac agctaagaat agtagaagtt aatctgataa aaatcgaaaa
    10681 aaccagtgga attccgtgtc agggtaagtt ccactggttt tcatagtcta ttaaagttcg
    10741 aatgaaacct atttataata tattgaaact agaatagtac acctctaatt ctaaaacatt
    10801 gttagaaatc gatttgactg tcctgatcta ttcgtactat tcttatttca ttttactata
    10861 ttttggtgca ataagtgaaa agtagtccga ataatataag gattgatttt atagttttta
    10921 aactcaaatg aattaaaata aagagagtac gaaaattctc atctgaaagt attttagaat
    10981 aattctcttc gtgaatttct tcaaaacaga tagcttcatc ttaggtatgt gttaattgga
    11041 tttcgtaagc tctatttaca atcgtaaagt tatgcactga aaaagttgta gttagtcttc
    11101 cagtttgcta aatttctcga atagtatctt ttttaggtat gtgattttta ggtatgtgat
    11161 ttttaggtat gtgatttctt tttgcatttt tgagttagat aaggtataat ggttttattg
    11221 tcttttgggg tcgttacgga ttcgacaggc attatgaggc atattttgcg actcgtgtgg
    11281 cgacgtaaac gctcagttaa atataactgc aaaaaataac acttcttacg ctctagctgc
    11341 ctaaaaacca gcaggcgtga cccgatttgg attgctcgtg ttcaatgaca ggtcttatta
    11401 ttagcgagat acgattaagc cttgtctagc ggcttgataa gagattgata gactcgcagt
    11461 ttctagactt gagttatgtg tcgaggggct gttaaaataa tacataacct atggttgtag
    11521 acaaatatgt tggcaggtgt ttggacgtgg gttcgactcc caccggctcc attattcctt
    11581 tgcattcttt tgcattcctt ggtaaaacgt tgttaaatca acgtttttta tttttatctt
    11641 tggtattcct ttgcattctt ttgctaaaaa gggagtcaca aacagaccct attttaaaaa
    11701 aaggatagaa aaaaggatac aacatttgtc gcatcctaga aatctatgta cttcgtaaag
    11761 cgttctccga ttcgagtatt cctctgcatg ctttagtaaa tataggattt tttgtagtta
    11821 cttccctaat tggatttcta attgttcttt atctgagaaa ttcaaaatgt taataccata
    11881 ctcttgtaga gcgatttgat ggtcatcttt gatattatta tacccttcat cgcttacaat
    11941 gatatacaac tgttctgtat ctccatattc ttttctacgg tattcagatg tatctaacca
    12001 actagctaag atagtatcaa cttgttgttt ggttatgtta ttgtgaactc tggctatttt
    12061 tgaaatacct ttactcataa acacaaaatt aaagcggtgt tctaaacgag atttacctgc
    12121 aattgagaaa gctggaaaga ctgtgtaatg ctcatttttc atgaagtaag atttaacatc
    12181 gtctaaaaat tgagatttaa tattgttagg tgttagctga ataaagtcat aaacattcat
    12241 cagcaattgt gtcatatcat gtatgacttg tcctagatgt tctttaccag tcgtccgttc
    12301 gattgctcca tcgtgtaaat caaatccatt aaagtggaga agtgagttaa agatgtcttg
    12361 acgtcgccct ttttttgtaa catcaatatt attaatggat aaattccaga tagtataacc
    12421 atcatctgta actgtcaaat gttttccatt gctttttatt gagaaaccaa tagcttcacc
    12481 taatgggtct ataaaaggag taatcacttc agtatgagta tcagtcacat cgttaaaaac
    12541 agcgttttct tttatgtaat ttagataggt atttttgata tcagtagcat tcatgatatt
    12601 ctcctttctt tatagggtga ttataacaaa tcctcttgta tattaattgc tatattttca
    12661 ggattgttca cattggtata gtcaagcaaa ttatcaagca tatccaggaa gtcatcagtg
    12721 ttaagaatat cttcataagg tagtggatag gctttgtaat gagttgtttc atcccctttt
    12781 tgataatact cttcttcaga gaagatgtta actcgattgc cccaaacttt ctcgccgttt
    12841 gcgttcttat ggaatttatt atttagattg attcgtaaga gagtatagtt gtgttgagtt
    12901 tcccttagat gaaaaacttt gcttgtagtg ctgtagaagt agttcaaaat aaatctagta
    12961 tcatgcttgc caacaaggtt aatagtacct gaactgcgat tcgtaagagt tcgattgtgt
    13021 ttattagcaa ttgctttaat tatttttatg agagctttag cttcactatc tgtcagaagt
    13081 aactctttca tatctttcct ttctacttta tctacattct agagagtgga aatctggaat
    13141 gtagatcaga cagcgatcct tccgtataca tctggtttct taaagagagc tatgatgcct
    13201 tggaaaagtg caataatagc aggtattcct gttaaagata aaatcagaaa aaggaaacct
    13261 tttccgttat atcctgcgta aaaatgatgt atacccaatc cacctaaaaa taaagcaaga
    13321 ataacataaa cccacttatt aacataatgt acacctgtag ctatttcttg agtgtgaacg
    13381 acttgtgact gattttgcat agcgttgttt tcattgacaa tgttaatatt aattttgtcg
    13441 tcttttttat ctttaacttt tatgacgata atctcaccat ctactttatg aacttcgact
    13501 tcgtcaccta attttggaac aaaattcaat tcagatggat ttacttttaa atactcttca
    13561 ttatgggaga ttacaacctc tgctcctgta actttaacaa cttttgacat tttgtttttc
    13621 ctttcatttt accatctata gattttaata atgagctttg atatttattt tatctgtttt
    13681 tataagtaaa gtatatcaaa aaaagtacga aaagaaaatc ttttatggtt tagttaaaaa
    13741 gcaagagttt aagaaactgg attaattaaa cttgaagtat ttgagatttt gtcttttact
    13801 gttcgtaaaa tcgtatgaga taagaaggga gtggaaagaa ttcatactct ctctagaact
    13861 tgtatattga aacgatgtgg agattgtaaa gaaattacaa aataccccaa aactaagata
    13921 gaaatacaaa gtttcagggt atcatatatt ttatctgttt ttccacggaa gacatgggat
    13981 tcgaacccac gcacgctatt acacgcctac cgcgtttcca acacggcctc ttaagcctct
    14041 tgagtaatct tccaatactt actcaaatag tctaccataa aggctcttat cttgcaataa
    14101 aaattctaga aataagaaaa atgatagatt ttgaaagaaa atgataaaaa atgcttgact
    14161 tcaaaagaaa gtatggtaga atgaatagtg taaacgataa caggaggtga ttcagtgtta
    14221 aaaacagaac gtaaacaact gattttagag gagttaaatc aacatcatgt agtttctcta
    14281 gaaaaattag ttagtttgct agaaacgtca gaatcaacgg ttcgaagaga cttggatgag
    14341 ttggaagcgg aaaacaagct tcgtcgtgtg catggtggag cagaactccc ccactcctta
    14401 caggaagaag aaaccattca agaaaaatct gtcaaaaacc ttcaagaaaa gaaattgctg
    14461 gctcagaaag cagcctctct cattaaagaa aaagatgtca tctttatcga tgctggaaca
    14521 acaactgctt ttttgattca tgaattggtc aataagaatg ttacagttgt gaccaactcc
    14581 attcaccatg ccgctcagtt ggttgaaaag cagattccaa ctgtcatggt tggaggaaac
    14641 gtcaagacgg cgacagatgc tagtatcggg ggcgttgctc ttaaccagat taaccaattg
    14701 cactttgacc gtgcctttat cggaatgaat ggtgttgacg atggctatta tacgactcct
    14761 gatatggagg agggagctgt gaaaagagct attttggaga atgccaagca gacctacgtc
    14821 ttggtggatt cgtcaaaaat tggacaaact tgctttgcca aggtagcccc actcaaacgc
    14881 gctatcgtta tcactagtca agggcatgag ctcttgcagg ttattaagga gaaaacggag
    14941 gtaatagaag tatgatttat acagtcacac tcaatccatc cattgactat atcgttcgtt
    15001 tggaccaagt caaagttggt agtgtaaatc gtatggacag tgatgataag tttgctggtg
    15061 ggaaaggaat caatgtcagc cgtgtcttga aacgtttgaa tataccaaat acagcgacgg
    15121 gatttatcgg tggctttact ggtaaattta tcacagatac tttagcagag gaagaaatcg
    15181 agacacgttt tgtccaggtg gcagaagata ctcgtatcaa tgttaaaatc aaagcagacc
    15241 aagaaacaga aatcaacgga acgggtccaa ctgttgaacc ggttaagcta gaagaattga
    15301 aagctatttt atctagtctg acagcagaag atacagttgt ctttgcaggt tcaagtgcta
    15361 aaaatctagg caatgttatc tataaggatt tgatttcctt gacgcgccag actggtgcgc
    15421 aagtggtctg tgactttgaa ggacagacct taattgatag tttggactac cagcctcttc
    15481 ttgtaaaacc aaacaatcat gaacttggag cgatttttgg ggttaaactc gaaagtttag
    15541 atgaaattga gaaatacgct cgtgagttac tggctaaggg tgctcaaaat gttattatct
    15601 ctatggctgg tgatggtgcc cttcttgtca catctgaggg agcttacttc gctaaaccaa
    15661 tcaaaggaac agtcaaaaat tcagttggag ctggtgattc tatggttgct ggattcacag
    15721 gtgaatttgt caaatcaaaa gacgcagtag aagccttcaa atggggagtg gcttgcggaa
    15781 cggcaactac cttctcagat gacttggcaa cggcggaatt tattaaagaa acatatggaa
    15841 aagttgaggt agaaaaacga tgaaaattca agatttattg agaaaagatg tcatgttgct
    15901 ggatttgcag gcaactgaaa agactgctgt cattgaagag atgattaaaa gcctaacagg
    15961 ccacggttat gtgacagatt ttgaaacatt taaagaagga attttggcgc gtgaagcttt
    16021 gacttctact ggtttgggtg atggaatcgc aatgcctcac agcaaaaacg ctgctgtcaa
    16081 agaagcgaca gttctctttg ctaagtcaaa caagggtgtt gactatgaga gtttggatgg
    16141 gcaggcaact gacctcttct tcatgattgc agctccagaa ggtgccaatg atactcactt
    16201 ggcagcattg acagaattgt ctcaatactt gatgaaagac ggttttgcag acaaacttcg
    16261 tcaagcaaca tctgcagacc aagttgtcga actttttgac caagcttcag aaaaaactga
    16321 ggaacttgtt caagcacctg ctaatgactc tggtgacttt atcgtagctg ttacagcttg
    16381 tacaacaggt attgcccaca cttacatggc ccaagaagcc cttcaaaaag tagctgctga
    16441 aatgggggtt ggtatcaagg tcgaaaccaa cggtgctagc ggtgttggaa atcaactaac
    16501 tgcagaagat atccgtaagg ctaaagctat tatcattgca gtagacaagg ccgttgaaat
    16561 ggatcgattt gatggaaaac cattgatcaa tcgtccagtt gctgacggta tccgtaagac
    16621 agaagagtta attaacttgg ctctttcagg agatgcggaa gtctaccgtg ctgctaatgg
    16681 tgcaaaagct gcaacagtct ctaacgaaaa acaaagcctt ggtggtgcct tctacaaaca
    16741 cttgatgagt ggtgtatctc aaatgttacc attcgttatc ggtggtggta tcatgattgc
    16801 ccttgccttc ttgattgacg gtgctttggg tgttccaaat gaaaaccttg gcaatcttgg
    16861 ttcttaccat gagttagctt ctatgttcat gaaaattggt ggagctgcct ttggtttgat
    16921 gcttccagtc tttgcgggtt atgttgccta ctctattgct gaaaaaccag gtttggtagc
    16981 aggtttcgtg gctggtgcta ttgccaaaga aggttttgcc tttggtaaaa ttccttatgc
    17041 cgcaggtggt gaagcaactt caactcttgc aggtgtctca tctggtttcc taggtgccct
    17101 tgttggtgga tttatcgcag gtgccttggt tcttgccatc aagaaatacg ttaaagttcc
    17161 tcgttcactc gaaggtgcta aatcaatcct tctattgcca cttcttggaa caatcttgac
    17221 aggatttgtt atgctagctg taaatatccc aatggctgca atcaacactg ctatgaatga
    17281 cttcctaggc ggtcttggag gaggttcagc tgtccttctt ggtatcgtcc ttggtggaat
    17341 gatggctgtt gatatgggtg gaccagttaa taaagcagct tatgtctttg gtacaggtac
    17401 gcttgcagca actgtttctt caggtggttc tgtagccatg gcagcagtta tggctggagg
    17461 aatggtgcca ccacttgcaa tctttgtcgc aactcttctt ttcaaagata aatttactaa
    17521 ggaagaacgt aactctggtt tgacaaacat catcatgggc ttgtcattta tcactgaggg
    17581 agcgattcca tttggtgccg ctgacccagc tcgtgcgatt ccaagcttca tccttggttc
    17641 agcagtagca ggtggactcg ttggtcttac tggtatcaaa ctcatggcgc cacacggagg
    17701 aatcttcgtt atcgccctta cttcaaatgc tctcctttac ctcgtttctg tcttggtagg
    17761 agcaatcgta agtggtgtgg tttatggtta cctacgcaaa ccacaagcat aaaaaataga
    17821 aaaatgaaaa gattggaccg tttggtgcag tctttttctc ttcccgaaat gcctgtgaaa
    17881 tatggtataa tagaagaatg gcaaacaaga atacaagtac aacaagacgg agaccgtcta
    17941 aagcagaact ggaaagaaaa gaagcgattc aacgaatgtt gatttcatta ggaattgcga
    18001 ttttattgat tttcgcagcc ttcaaattag gggctgcagg tataaccctt tataatttaa
    18061 ttcgcttgct agtgggtagc ctagcttatc tggcgatatt cggcctatta atctatctct
    18121 tctttttcaa gtggatacga aaacaggaag gactcttatc tggctttttc accatatttg
    18181 ctggcttact cttgattttt gaagcctact tggtttggaa atatggtttg gacaagtccg
    18241 ttctaaaagg gaccatggct caggttgtga cagatctgac tggttttcga acgactagct
    18301 ttgctggagg gggcttgata ggggtcgctc tttatattcc aacagccttt ctcttttcaa
    18361 atatcggaac ttactttatt ggttctatct tgattttagt gggttctctc ctagtcagcc
    18421 cttggtctgt ttacgatatt gctgaatttt tcagtagagg ctttgccaaa tggtgggaag
    18481 ggcacgagcg tcgaaaagag gaacgctttg tcaaacaaga agaaaaagct cgccaaaagg
    18541 ctgagaaaga ggctagatta gaacaagaag agactgaaaa agccttactc gatttgcctc
    18601 ctgttgatat ggaaacgggt gaaattctga cagaggaagc tgttcaaaat cttccaccta
    18661 ttccagaaga aaagtgggtg gaaccagaaa tcatcctgcc tcaagctgaa cttaaattcc
    18721 ctgaacagga agatgactca gatgacgaag atgttcaggt cgatttttca gccaaagaag
    18781 cccttgaata caaacttcca agcttacaac tctttgcacc agataaacca aaagatcagt
    18841 ctaaagagaa gaaaattgtc agagaaaata tcaaaatctt agaagcaacc tttgctagct
    18901 ttggtattaa ggtaacagtt gaacgggccg aaattgggcc atcagtgacc aagtatgaag
    18961 tcaagccggc tgttggtgta agggtcaacc gcatttccaa tctatcagat gacctcgctc
    19021 tagccttggc tgccaaagat gtccggattg aagcaccaat ccctgggaaa tccctaatcg
    19081 gaattgaagt gcccaactcc gatattgcca ctgtatcttt ccgagaacta tgggaacaat
    19141 cgcaaacgaa agcagaaaat ttcttggaaa ttcctttagg gaaggctgtt aatggaaccg
    19201 caagagcttt tgacctttct aaaatgcccc acttgctagt tgcaggttca acgggttcag
    19261 ggaagtcagt agcagttaac ggcattattg ctagcattct catgaaggcg agaccagatc
    19321 aagttaaatt tatgatggtc gatcccaaga tggttgagtt atctgtttac aatgatattc
    19381 cccacctctt gattccagtc gtgaccaatc cacgcaaagc cagcaaggct ctgcaaaagg
    19441 ttgtggatga aatggaaaac cgttatgaac tctttgccaa ggtgggagtt cggaatattg
    19501 caggttttaa tgccaaggta gaagagttca attcccagtc tgagtacaag caaattccgc
    19561 taccattcat tgtcgtgatt gtggatgagt tggctgacct catgatggtg gccagcaagg
    19621 aagtggaaga tgctatcatc cgtcttgggc agaaggcgcg tgctgcaggt atccacatga
    19681 ttcttgcaac tcagcgtcca tctgttgatg tcatctctgg tttgattaag gccaatgttc
    19741 catctcgtgt agcatttgcg gtttcatcag gaacagactc ccgtacgatt ttggatgaaa
    19801 atggagcaga aaaacttctt ggtcgaggag acatgctctt taaaccgatt gatgaaaatc
    19861 atccagttcg tctccaaggc tcctttatct cggatgacga tgttgagcgc attgtgaact
    19921 tcatcaagac tcaggcagat gcagactacg atgagagttt tgatccaggt gaggtttctg
    19981 aaaatgaagg agaattttcg gatggagatg ctggtggtga tccgcttttt gaagaagcta
    20041 agtctttggt tatcgaaaca cagaaagcca gtgcgtctat gattcagcgt cgtttatcag
    20101 ttggatttaa ccgtgcgacc cgtctcatgg aagaactgga gatagcaggt gtcatcggtc
    20161 cagctgaagg taccaaacct cgaaaagtgt tacaacaata aaaaaatagc ttctttccaa
    20221 gtttggaggg aagctatttt agtggctatt gattgctttt attttctgaa gttggcgcat
    20281 tggactgttt ttcgttttca gtagcaggtt tacttgaagc aggagtagaa gagtcctgag
    20341 ttgctgtttt ctgatcttct tttttctctt ccttgacgct agattttggt gtttcctctt
    20401 gctgtgtttt ttcttgacta gtgttagtct ctttagttgg actggtgttt tccttagggg
    20461 attccttttg gatttctttg acaatggttg tcgtctggct tgtcgtaggt tcttttttaa
    20521 tatttttgtt attatccaag gcgttcataa tcgtgatact tgcggtaatc aagccaagga
    20581 tactagcgat tgtagcaacg gttttttgaa agactgtaaa gccttttttg atgtgttctg
    20641 tttttggttt tgaagttcta cgataattag acatacattc tctcctttaa ttaaaattta
    20701 ttatacctca tttctttaaa aaaatcttaa aaaaagagga gatttttcta cacgaacttc
    20761 agtaattagt tgaaataaaa tatgacttat gatataacaa aataaagaaa gcgatttcaa
    20821 aaaaggaggg cgttatatgt tcgaaattag aaatttgagt ctctcttttg caggcaggcg
    20881 gttgctagag ccaacagatt tgatatttga aaggggaaaa gtatatacaa tatatgggaa
    20941 gtcaggcgta ggaaagtctt ctttactgaa taaaattggt ttgctctctg ctacggatcc
    21001 tagtgtttct tatttcttcg atggaaaaga gattgatatc gaaaataaga aatcagtctc
    21061 tgtctttata gctgaagaag ttgcctttgt atttcagggg cgaaatctaa taaatgattt
    21121 gaccgtattt gaaaatttaa gactagcttt aaacttttat gacttgagtc cagatgaaat
    21181 agaaagcaaa attgatacag tattggcgga tttacagatt tcttctttaa agcatgctta
    21241 tccagaagat ttatccggtg gtgaagaaca acgagtggca atcgcaagag ccttagttac
    21301 aggaaagact ctcatcttag ctgatgaacc aacaagttct ttggataaag aaaatagaga
    21361 aaaaatctcc gccttgttaa ttgatttagc tcacaaatat cataaaattg tattgattgt
    21421 ttcgcatgat gaggcgatga ttgcaatagg agatgttcag cttcatttta aagaccataa
    21481 attagttggg aattgtctta ttttgaattc tgatgaaggg ataaaggatt ctaagaagtg
    21541 gtcctcctgt ttgtcgtctt ctcatacgaa gctatccgtt ttgaaacata gaaggccttt
    21601 tttacctaga ttattagcgt tttttatctc tcttgtagtt gctatagcag taacctctat
    21661 taactttcag tccttatttg cagataagta tcaccaactg gtgaacaact cactcgaaaa
    21721 tggcttcttg gtgattaatg attcgcttca tttacaaact acaaaagtgt tggatgattt
    21781 tctcagtttt gataaggagg aaatcacctc aattagcaca agtcagaata ttcaaaccgt
    21841 caatccttat atagagtttc tctctttggg tatgacgttt gataattcaa aagactattc
    21901 acaacttcaa aagaactttc agccaacttt gactattgat ggtcagacca gaagcttgac
    21961 aagaaatttt tcaattcaac ccttgtatca gacaaataca acacagaggc agatagagta
    22021 ttttgatagg agcaatgaaa aagggattta tctatctgag caattcattt cagatgaaaa
    22081 attaccaaat atagtttcgg gaactaccgt gacactgact ttttatattc caatttcttt
    22141 atatgaatca agtatagaga aagaggggaa tatattgaaa ggagatggcg gtttatttgt
    22201 caaagtggat aaaacatatc ctgttttagg gattgttaaa aaaagttatc cgtttgaata
    22261 ttccccttat gggaacaccc tatttatgaa tattgctgaa atggaagaat tgcaaaatga
    22321 agcaattcaa cagcatccca tgacgaagat ggctttagat ggttttcctt tgaaatcatg
    22381 gatgccgagt gcgattcatg tgttactaaa ggatagcggt gctattcctg aagaattgag
    22441 tagaataaga gcaatctctt cacaaattac tattttatca tcatatgaaa actacgaaga
    22501 atttaataaa ggactcacct atatcaggca atttttaatg ttgctatccc tagtcttact
    22561 catccttgtc atcgcagtat tgtcctttgt tttctttttg ctcaatcgtc ctcgacgctt
    22621 tgaagtaggg attttaaaat ctttgggata cagtactcaa aatattgttt ggcttttctt
    22681 aaaagaatta attggttatg gtaaaacaat ttcgatatta gcaagttgtt tactcgtcat
    22741 tctttccatt ttagcaatgc aagtgcttaa attggaaatt tcagatgttt ttaaattcta
    22801 tctaacttcc gttttcacct taattggatt atcagtctca gtactgataa taagtggctt
    22861 actacctata tacacaactt gtaggcaaac agttgtcgat actatccgaa agaatggatg
    22921 aggtgatatc atgaaacata agataatgaa aaaaataata gtggtagtgt ttgctatccc
    22981 atggttaaca tttttaagtc aagtacatgc agattatgta agtaagtcta gttctttaga
    23041 cggttatagc ttggtaggct tgaatgttct taatgtgact tttaatgctt ctggctattc
    23101 tgatacttat agtggcagtg tgtcaaatat gtatttcact gactgggctt ggtttcctaa
    23161 tacgataagt aatcgttcca cttggaaaag ttcgattcca tatggtcaac gcgcaaatgg
    23221 tacagtccat ataggtgtag gagtaaattc gccttgggga gcggttaatc tctggggcgg
    23281 acaaaattac ttttctttag atttttaaca gaaataatca aagttagata gaatgaataa
    23341 gaatgctctt gatgatggta tcaagagtat tttatgttat tcagattaat gcaaacattg
    23401 ccctttcttg tcgcaggctc cgtttcatga tacaatagaa ggagtgattt tagaaagcgt
    23461 gagaaacatg atttactttg ataattcggc gacgaccagt ccctatccag aagcccttga
    23521 aacctatatg caggtggctt caaaaatttt aggaaatcca tctagtctcc atcgtttggg
    23581 agaccaggca acacgaattt tagatgcttc ccgtcaacag attgcagatt taatcggtaa
    23641 gaaaagtgat gaaatcttct ttacatctgg tgggacagaa ggggataact ggatcatcaa
    23701 gggagtagca tttgaaaaag cccagtttgg caagcacatc atcgtatcag ccattgaaca
    23761 tccagcagtt aaggaatcag ccctctggtt gaaagctcaa ggttttgaag tggattttgc
    23821 tccagttgat aacaaaggat ttgtggatgt tgaggcgcta gaagatttga taagacctga
    23881 tacgaccctc gtttccatca tggcagttaa caatgaaatt ggctctgttc agcccattga
    23941 ggctatttca aaactattgg cagacaagcc aactatttcc ttccacgttg atgcggttca
    24001 ggcgcttgcc aagattccga ctgaaaagta tctgacagaa cgagtggatt tcgcgacttt
    24061 ctctggtcac aagttccacg gaatccgtgg tgttggtttt atctatatca agtctggcaa
    24121 gaagattacg cctcttttaa caggtggtgg tcaggaacgt gattaccgtt cgacaactga
    24181 aaatgtggca ggaattgcag cgaccgctaa ggctctccgt ttatctatgg aaaagctaga
    24241 tatctttagg agcaagactg ggcagatgaa ggcagtgatt cgtcaagcac ttctggacta
    24301 tccggatata tttgtctttt cagatgagga agacttcgcc cctcatattc tgacttttgg
    24361 aatcaagggt gttcgtggtg aggtcattgt tcacgccttt gaagactatg atattttcat
    24421 ctcaacgacc tcggcttgtt cgtccaaggc tgggaaacca gccggaaccc tgattgctat
    24481 gggagtggac aaggataagg ctcagtcagc tgtgcgtctt agtctagacc ttgaaaatga
    24541 tatgagtcag gtcgagcagt tcttgaccaa gctaaaatta atttacaatc aaactagaaa
    24601 agtaagatag gagcattcat gcagtattca gaaattatga ttcgctacgg tgagctgtca
    24661 accaagggca aaaatcgtat gcgtttcatc aataaacttc gcaataatat ttcagacgtt
    24721 ttgtctatct atccccaagt taaggtaaca gcagatcgcg accgtgccca cgcttacctc
    24781 aatggagcag attacacagc agtagcagaa tcgctcaaac aagtatttgg aattcaaaac
    24841 ttttcccctg tttataaggt tgaaaaatct gtagaagttc tgaagtctgc tgtccaagag
    24901 attatgcagg acatctataa ggaaggcatg acctttaaaa tctctagcaa gcgtagcgac
    24961 cacacctttg aattggacag tcgtgaactc aaccaaacgc ttggaggggc tgtattcgaa
    25021 gccattccaa acgtacaagc tcaaatgaaa agtcctgaca tcaatcttca ggtggagata
    25081 cgtgaagaag cagcctatct ttcttatgaa accgttcgag gggcaggtgg attaccagtg
    25141 ggaacttctg gtaagggcat gctcatgttg tcagggggaa tcgattcccc tgtagctggc
    25201 tatctagcgc ttaaacgagg ggtagatata gaggcagttc actttgccag cccaccttac
    25261 acgagtcctg gtgctcttaa aaaagcccaa gatttgaccc gtaaattaac caaatttggg
    25321 ggaaatatcc agtttatcga agttcctttt acagagattc aagaggaaat caaagccaaa
    25381 gcgccagaag cctaccttat gaccttgacg cgtcgtttta tgatgcgtat tactgaccgt
    25441 attcgtgagg tacgaaatgg tttagttatc atcaatgggg aaagtctagg tcaagtagcc
    25501 agccaaaccc ttgaaagtat gaaggctatc aatgctgtta ccaacactcc catcattcgt
    25561 cctgtggtta ccatggacaa gttggaaatc attgacatcg cccaggaaat cgataccttt
    25621 gacatttcaa tccaaccgtt tgaagactgt tgtaccattt ttgcaccaga tcgtccaaaa
    25681 acaaatccta aaattaagaa tgcggagcag tacgaagcgc gtatggatgt tgaaggcttg
    25741 gttgagcgag cagtggctgg aatcatgatt actgaaatca cacctcaagc cgaaaaagat
    25801 gaagttgatg acttgattga caatctgctc taattcagaa aatccaaaag aatagcgaaa
    25861 atcagtaaaa aaagttagtt ttttctctaa aaacaggtga aaaactaact ttttttattt
    25921 ttatgatata atgatataaa attttgaata tagagagttt tctgacaatg aatcaatcct
    25981 acttttatct aaaaatgaaa gaacacaaac tcaaggttcc ttatacaggt aaggagcgcc
    26041 gtgtacgtat tcttcttcct aaagattatg agaaagatac agaccgttcc tatcctgttg
    26101 tatactttca tgacgggcaa aatgttttta atagcaaaga gtctttcatt ggacattcat
    26161 ggaagattat cccagctatc aaacgaaatc cggatatcag tcgcatgatt gtcgttgcta
    26221 ttgacaatga tggtatgggg cggatgaatg agtatgcggc ttggaagttc caagaatctc
    26281 ctatcccagg gcagcagttt ggtggtaagg gtgtggagta tgctgagttt gtcatggagg
    26341 tggtcaagcc ttttatcgat gagacctatc gtacaaaagc agactgccag catacggcta
    26401 tgattggttc ctcactagga ggcaatatta cccagtttat cggtttggaa taccaagaaa
    26461 aaattggttg cttgggcgtt ttttcatctg caaactggct ccaccaaccg ctatatcgag
    26521 tgccagaaac tatcgcctga ccaacgcatc ttcatctatg taggaacaga agaagcagat
    26581 gatacagaca agaccttgat ggatggcaat atcaaacaag cctatatcga ctcgtcgctt
    26641 tgctattacc atgatttgat agcaggggga gtacatctgg ataatcttgt gctaaaagtt
    26701 cagtctggtg ccatccatag tgaaatccct tggtcagaaa atctaccaga ttgtctgaga
    26761 ttttttgcag aaaaatggta agttaagaaa ggaaaaaacg aaatgcatat tgaacatctt
    26821 agccactgga gtggtcatcc taaccgtgaa atgtacctta accgttatgg acatggtggg
    26881 attccagttg tggtctttgc ttcatcaggt ggtagtcaca acgaatacta tgattttggc
    26941 atgattgatg cctgtgcttc ctttatcgag gaaggccgtg tccagttctt taccctatct
    27001 agtgtggata gtgagagctg gttggctact tggaaaaatg ctcatgacca agcggaaatg
    27061 caccgtgcct acgaacgtta tgtgattgag gaggccattc ttttatcaag cacaagacag
    27121 gttagtttga tggcatgatg acgacaggtt gctctatggg agcctatcat gcactcaatt
    27181 tcttcctcca gcatccagat gtctttacca aagtgattgc tctcagtggt gtttacgacg
    27241 cacgtttctt tgtcggtgat tactacaacg atgatgctat ttaccaaaac tcgccagtag
    27301 attatatttg gaaccaaaac gatggctggt ttattgaccg ttaccgtcag gcagagattg
    27361 tgctgtgtac ggggcttgga gcctgggaac aagatggttt accatccttt tacaagctca
    27421 aagaagcctt tgaccagaaa caaattccag cctggtttgc tgaatgggga catgatgtcg
    27481 cccacgactg ggaatggtgg cgtaaacaaa tgccttattt cctcggtaat ctctatttat
    27541 aaaaggagtt acctatgaat taccttgtta tttctcccta ctatccacaa aactttcaac
    27601 agtttaccat cgaactagct aataaaggca tcacagtctt gggaattggt caagagtctt
    27661 acgagcaatt ggatgagccc ttgcgcaata gcttgaccga gtattttcgt gttgataatc
    27721 ttgagaacat agatgaagtc aaacgtgcag ttgcttttct cttttataaa catggtccaa
    27781 ttgaccgcat cgagtctcac aatgaatact ggcttgagct agacgcaaca ctcagagaac
    27841 aattcaatgt ttttggtgcc aaaccagagg atctcaaaaa gacgaaatat aagtctgaaa
    27901 tgaagaaact tttcaaaaaa gcaggtgttc ctgtggtacc tggagctgtt atcaagacgg
    27961 aagcagatgt tgatcaagca gtgaaagaaa tcggtcttcc aatgattgcc aaacctgata
    28021 atggagtggg agcagccgca acctttaaac ttgagacaga agacgatatc aatcacttca
    28081 agcaagaatg ggaccattca accctttatt tctttgaaaa atttgtcact tccagcgaaa
    28141 tctgtacctt tgacgggctc gtggacaagg atggaaagat tgtcttctca acaacctttg
    28201 actacgccta tacaccgctt gacctcatga tttataagat ggacaattct tattatgtgc
    28261 tcaaggatat ggatcctaaa ctgcgcaagt atggggaagc aattgtcaaa gaatttggta
    28321 tgaaagaacg gtttttccat attgagttct tccgtgaggg ggacgattat attaccatcg
    28381 agtacaataa ccgccctgca ggtggtttta ccattgatgt ttataacttt gctcattcct
    28441 tggaccttta tcgtggctat gcagctattg tcgcaggaga ggagttcccg gcgtcagact
    28501 ttgaaactca gtattgtttg gctacttctc gccgtgcaaa tgctcactat gtttattcag
    28561 aagaggattt gcttgccaaa tatagccagc agttcaaggt taaaaaagtc atgccagctg
    28621 ccttcgcgga acttcaagga gattacctgt atatgctgac aactccgagt cgacaagaaa
    28681 tggatcagat gattgctgat ttcggacaac gtcaagaata agaactatcg gattaaggaa
    28741 attcactccc ttaatccttt tgttttgtct ggtaaaaaat aagagcatcc taacaaggta
    28801 gctatcataa aacttgttcg ataactattt gaagcaggat taggtggcta gaaattgaat
    28861 tttaacattt caatttagtc atagtattgt gttttcgtat ccttaaatca gctaaaagga
    28921 tccatgacga cacctatacg atatagtttt caggatacca aaccagtcta ttaatactca
    28981 atgaaaatca aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag
    29041 gttgtggata gaactgacag agtcagtatc atatacctac ggcaaggtga agctgacgta
    29101 gtttgaagag attttcgaag agtataaatc ttattgatga actgcttgca gtctgagaaa
    29161 aaatgagctt ggatattatt tccaaactca cttaaagtca atttcaatcc actagaacaa
    29221 gcctagtaca gttccatcgc tttcaacatc catgttgaga gctgctggac gttttggaag
    29281 acctggcatg gtcataacat caccagttaa ggcaacgatg aagcctgcac ctaattttgg
    29341 taccaattca cgaatggtaa tttcaaagtt ttctggtgct ccaagcgcat ttggattgtc
    29401 tgagaaactg tattgagttt tagccataca aattggcaat ttgccccaac cattttgaac
    29461 gatttgagca atttgtgttt gagctttctt ctcaaagttc actttgctac cacgatagat
    29521 ttcagtgaca attttttcaa tcttttcttg gacagaaagg tcattatcgt acaaacgttt
    29581 atagttagct ggattttcag caattgtctt aacaactgtt tcggcaagtg ctactccacc
    29641 ttctgctcca tcagcccaga cactagccaa ttcaactggt acatcgattg aggcacagag
    29701 ttcttttaag gctgcaattt cagcttctgt atcagataca aattcgttaa tagctacaac
    29761 tgctggaata ccgaacttac ggatattttc aacgtggcgt ttcaagttag caaaacctgc
    29821 acgaactgca tctacatttt cttcagtcag agcgtcttta gccacaccac cattcatctt
    29881 aagggcacga agggttgcga caataacaac tgcatctgga gatgttggca agtttggtgt
    29941 cttgatatca aggaatttct cagcaccaag gtccgcacca aaaccagctt cagtaacagt
    30001 gtaatcagcc aagtgaaggg ctgttgtcgt cgccaaaaca gagttacagc catgagcgat
    30061 attggcaaat ggaccaccgt gtacaaaggc aggtgtaccg taaattgtct gaaccaagtt
    30121 tggcttaata gcatccttca aaatcaaagc caaggcaccc tcaacctgca aatcacctac
    30181 agaaacaggc gtacggtcat agcgataacc aataacgata ttcgccaaac gacgtttcaa
    30241 gtcctcgatg tccgttgcca agcaaagaat tgccatgatt tctgaagcaa ctgtaatatc
    30301 aaaaccatcc tcacgtggaa taccgtttag aggaccacca agaccaacag tcacatggcg
    30361 gagcgcacgg tcgttcaagt ccacaacgcg tttccagagg atacgacgtt gatcaattcc
    30421 cagctcattc ccttggtgca agtggttgtc aatcaaggca gaaagggcat tgttggcagt
    30481 tgtaatagca tgcatatctc cagtaaagtg gaggttgatg tcttccattg gcagaacttg
    30541 tgcataccca ccaccagcag caccaccctt gatccccatg actggaccaa gagacggttc
    30601 gcggatagca atcatggttt tcttgccaat cttgttcaag gcatccgcaa gaccaatggt
    30661 aagcgtcgac tttccttcac ctgcaggtgt tgggttgatg gcagtaacca agatcaattt
    30721 accaactgga ttgctctcaa ctgcacgaat tttatcaaag ctgagtttag ccttgtactt
    30781 tccgtacaac tccaaatcgt cgtaagaaat accaagtttc tctacaacat caacaattgg
    30841 cttcaactca atactctgtg cgatttcaat atctgttttc attcaaaatt cctctaacct
    30901 cttatatgat aattcattat atcacaaaac aagattttta acatcctaaa actctctaaa
    30961 cgttcgtaaa tatctctgtt tttaaggctt ttagagtcct ttcttaaatt ttatatggct
    31021 ttatagtttg aaactatagt aaatcttcgt ttttaccaaa aatttatcac tttcatttta
    31081 cttaccgctt atttttgtgt acaatagtgc tatgaaaatt ttagttacat cgggcggtac
    31141 cagtgaagct atcgatagcg tccgctctat cactaaccat tctacaggtc acttggggaa
    31201 aattatcaca gagactttgc tttctgcagg gcatgaagtt tgtttaatta cgacaaaacg
    31261 agctctgaag ccagagcctc atcctaacct aagtattcga gaaattacca ataccaagga
    31321 cattctaata gaaatgcaag aacgtgttca ggattatcag gtcttgatcc actcaatggc
    31381 tgtttctgac tacactcctg tttatatgac agggcttgag gaagttcagg ctagctccaa
    31441 tctaaaagaa tttttaagca agcagaatca tcaggccaag atttcttcaa ctgatgaggt
    31501 tcaggttttg ttccttaaaa agacacccaa aatcatatcc ctagtcaagg aatggaatcc
    31561 tactattcat ctgattggtt tcaaactgct ggttgatgtt accgaagatc atctggttga
    31621 cattgcacga aaaagtctta tcaagaatca agcagattta atcatcgcga atgacctgac
    31681 tcaaatttca gcaggtcagc accgagctat atttgttgag aaaaatcagc ttcaaacagt
    31741 ccagactaaa gaagaaattg cagaactcct ccttgaaaaa attcaagcct atcattctta
    31801 gaaaggaaaa ctatggcaaa cattctcttg gctgtaacgg gttcaatcgc ctcttataag
    31861 tcggcagatt tagtcagttc tctaaaaaaa caaggccatc aagtcactgt cttaatgact
    31921 caggctgcta cagagtttat ccaacctttg acactacagg tactctcaca gaatcctgtc
    31981 cacttggatg tcatgaaaga accctatcct gatcaggtca atcatatcga acttggaaaa
    32041 aaagcagatt tatttatcgt ggtacctgca actgctaaca ctattgcaaa actagctcac
    32101 ggatttgcgg acaacatggt aaccagtaca gctctagccc taccaagtca tattcccaaa
    32161 ctaatagctc ctgctatgaa tacaaaaatg tatgaccatc cagtaactca gaataatctg
    32221 aaaacattag aaacctacgg ctatcagctg attgctccta aggaatccct actagcttgt
    32281 ggagaccacg gacgaggagc tttagctgac ctcacaatta ttttagaaag aataaaggaa
    32341 actatcgatg aaaaaacgct ctaatattgc acccattgct atcttttttg ctaccatgct
    32401 cgtgatacac tttctgagct cacttatctt taaccttttt ccatttccaa tcaaaccgac
    32461 cattgttcat attcctgtca ttattgccag cattatttat ggtccacgag ttgggattac
    32521 acttggattt ttgatgggat tacttagctt gacggttaac acgattacga ttctaccgac
    32581 aagctacctc ttctctccct tcgtaccaaa cggaaacatc tactcagcta tcattgccat
    32641 cgtcccacgt attttgattg gtttaactcc ttacttagtc tataaactga tgaaaaacaa
    32701 gactggtctg attttagctg gagcccttgg ttccttgaca aatactatct ttgtccttgg
    32761 aggaatcttc ttcctatttg gaaatgttta taatggaaat atccaacttc ttctggcaac
    32821 cgttatctca acaaattcaa ttgctgaatt ggtcatttct gcaattctaa ccctagccat
    32881 tgttccacga ctacaaacct tgaaaaaata aaaacaatct ccgctttcaa acctgaaggt
    32941 ggagattttg ctctatacag tttcttttta atgaaatctt tactatagta aaacgaaata
    33001 agaacaggac aaatcgatca ggacagtcaa atagatttct aacaatgttt tagaagtaga
    33061 ggtggactat tctagtttca atctactata acttttaact aaaaaatgat ctataaaccc
    33121 aagtaaattc ttgctttatt gtctggttta ttgtaccata ctagtgtata tgcagttaaa
    33181 aaggagattc ttgtgaatac acggaaaaag acacaattta tgacaatgac agccctttta
    33241 acggctattg cgattttgat tccaattgtt atgcctttca agattgtcat tccacctgct
    33301 tcctatactt tggggagcca catcgctatt tttatagcca tgttcttgtc gcccttgatg
    33361 gcagtttttg tcatcctagc ctctagtttt ggatttttga tggctggcta tcccatggtt
    33421 atcgtttttc gggctttttc ccatatatct tttggtgctt taggagctct ttacctacaa
    33481 aaattccccg ataccctaga taaaccaaaa tcttcctggg ttttcaattt tgttttggct
    33541 gttgttcatg cccttgctga agtattagcc tgtgtccttt tttacgcaac ttcgggtacc
    33601 aatgtagaaa acatgttcta tgttctattt gtactagttg gatttggcac aattatccat
    33661 agtatggtag actatacatt agcactagct gtctataaag tgcttcgaaa acgccgttaa
    33721 aaggaaaagc tatgacaaaa gatcgcaaac aagccctgct ccaactcttg aaagaagctc
    33781 ctaaagccct taatggccaa agtttggcgg aacattttca tgtcacacgt caggtcattg
    33841 tgcaggacat tgcaattttg agagccgatg gcgctcctat cctatccacc aatcgtggct
    33901 acatctataa gcaaattgat accaatcctt atgttcacaa acttttcaaa gtgaaacatg
    33961 aagttgaaga aatcggtcag gaactccttg ctattgtcga taatggtggg catgtccaga
    34021 atactttgat tgaccatccc gtttatggag aaattgaaac cttgcttaaa ctgtcttgcc
    34081 gccgagacgt tcaacatttt ctagaacaag tcgagcattc tgattttaaa cctttatctg
    34141 aattgacaga tggtgtccat taccacctag tcgaagccga aacacaacaa gacctccact
    34201 atatcgagga ggccttggat cagctaggtt atttagtaaa ggattagaaa attttctttt
    34261 cccaatcgtc ttctgtacgg cgagggtaga aaaattcaga tttgtccgat gcttccatca
    34321 tctccatcaa aggtagcata tcataggcca gatccaagtt tggaatctgg tctttttgca
    34381 cccaagaaac ttctccttca tctgaagagc gaagggtacc agagaactca gttgccttat
    34441 aacaaacgac aatatagcgc ccacctgtat ctagtggcca atttttaatg ccgacaagtt
    34501 gaggattttg gatagtcaac cctgtttctt catagatttc acgaatgaca gactctgcga
    34561 aagattcgcc attttctaca tggcctcctg gaaaggcata accagaccag cgattagttt
    34621 caggagcgcg atactgcatc accacgcgct gagcttcgag atcttcaatc agacaaatat
    34681 ttgttaaaat cgttaattgt gctcgagaca taaatttact cactttctaa tttattaaat
    34741 ttttagactt gataccagta ccattagctt ctacttttta aaattattta gaatagaata
    34801 ccatccgttt ttcctttatg ggctttccaa gttcaagtat cttttcttgt tcatcaaaag
    34861 taaagcccat tttttgatag aaagcaattg cgcgcttatt atctttcaat acccataaga
    34921 aaatttcaga aaaatgatta agagcaatca aagctgcttt tattaacttt tgtgcgatac
    34981 cttttccata atagtctttt aaaacatata aagcaataat ttcgccagct tgaatagtct
    35041 catcacgaaa gttgccataa ctgataaaac caactacctt cataccatcc atcgcaatca
    35101 atgtattttc tggatacttt tgactaaaga atcgacatct ttctaatgtc attgtctcct
    35161 gaaattctgc aggcaaaagg ccatcataag cctctctcca cgtttgccag tgaacaaggg
    35221 gcttaccttc tatctcttca ggagtttcca ttgatttgat aataaccgtc atttgttttc
    35281 tcccagtctt ctctcaaaat accatattta atactatcaa aatatttacc ttgataataa
    35341 cgaacttttg gaatatgagc ttcttttttc attcttaatt tttcagcaag tttcatcata
    35401 ccaagattcc ctgaccaagt tgtcaaaccc agatgctcca actccaagta atcctgaaac
    35461 gtcctatcta tccactgcaa catagcaact ttcccaatac cagtgttcca gaatttttta
    35521 tcataaatac caattcccaa ttccatccat cttgtttgtt tacataccca ataacgcgaa
    35581 acagtcccaa ctagtttatc atcaacaaaa ataccaaggc gatttgagtt gcttaaaatg
    35641 gattctgatt tttgtagttc gaattcttta aaatttgaaa aatactgata atcatcataa
    35701 tagggagcat catactgttt ccaaactgga ttaagttgtg aataagccat ttcccataaa
    35761 gacatcaaat cttctctctt taactttctt aaataaatca tactattccc ctaatccaag
    35821 gccttgactt ccaacatcat atcacggatc tgagccgcca gttcaaagtc aagtacttcg
    35881 acggcttctt gcatttgttt ttctagtttc ttgacgagtt ctttgcgctc ttgtttgttg
    35941 aggctattga tgtcgacttc cttgtcctct tccttagcaa ctgccttggt cacagcaatc
    36001 aggtcacgga tttctttctt gattgtctgt ggtacgatac catgctcttc attataggcc
    36061 atctgaattt tccgacggcg ggcagtttca tcgatagcac gttgcataga ctgggtaacc
    36121 gtgtctgcat acatgatgac atggccttca ctgttacgag cagcacgtcc aatagtctgg
    36181 atgagtccac gttcgttgcg aaggaaacct tccttgtcag catcgagaat agctacgagg
    36241 ctcacttcag gaacgtcaat tccttcacgg agcaggttaa ttccgaccaa gacatcaaag
    36301 acacccaagc gcaggtcacg gataatctcc gtccgttcca aggtcttgat atccgagtgc
    36361 atgtacttaa ccttgatacc catttccttg aagtagtcgg tcaagtcctc tgccattttc
    36421 ttggtcaaag ttgtgataaa ggtacgctca tttttttcaa cgcgggcatt gatttcaccc
    36481 aagaggtcat caatctgtcc catagtcgga cggacttcca cctctggatc caagagtccc
    36541 gttggacgaa tgatttgctc aatcactgtc tcggtctgtt cattttcata gtcaccaggt
    36601 gtcgctgaaa cgtaaacaat ctgatgaacg tgactctcaa actcctcccg acggagagga
    36661 cgattgtcca aagcagacgg caaacggaaa ccataattaa ccagcatttc tttacgcgaa
    36721 cggtctccat tgtacatgcc cttgatttgc cctatggtca tatgactctc gtcaatcata
    36781 atcaagaaat catctgggaa gaagtcgaga agcgtataag gaggctctcc ttcgctccgt
    36841 ccatccatgt ggcgagaata attttcaacc ccattggtat agcccatctc acgcaacatt
    36901 tcgatatcat actctgtccg ctgtttcaaa cgctgggctt caagcagttt accttccttt
    36961 tcaaagacag ctaattgttc ttccaactcg gcctgaatct ttgcaatggc aacttccatg
    37021 tggtcgtcat tggtcacaaa gtgtgtcgct gggaaaatcg ctaaatgatc cacttctccc
    37081 aacacctgac ctgtcagagc ctcaacttca cgaatacggt caatttcgtc tccaaaaaat
    37141 tctactcgaa aggcatgttc atctcgggaa gctgggaaaa tctctaccac atccccacga
    37201 acgcgaaatc ttccgcgttg gaaatcaata tcattgcgtt caaactgaat atcgaccaag
    37261 tcattcaaga gtttatcacg agaaatctct agaccaggac ggagactaac gacactatca
    37321 gcgtattcct tgggcgaacc caaaccatag atacaagaga ctgaggccac gacaataaca
    37381 tcattacgct ccaaaagggc tgaggtagct gagtggcgaa gcttgtcaat ctcgtcattg
    37441 acagaactat ccttctcaat ataggtatcg ctagaaggga cataggcctc tggctggtaa
    37501 taatcatagt aggatacgaa atactcaact gcattttcag ggaaaaattc cttaaactcc
    37561 ccatagagct gaccagccag agttttattg tgggcaataa ccagagttgg tttattgact
    37621 ttagaaatga cctgactcat agtataggtc ttccctgttc cagtcgcccc catcagaatc
    37681 tgagcttttt ctcccccctc aatgttatcc accaactgct cgatagcttg gggttgatct
    37741 cctgatggtt gatattttga tactagttta aattgattat ctgtaatgtg attgatcata
    37801 agaatcctct ctccatgtgc tattcctatt ttagcatact tatagtattt tcacgaagaa
    37861 aaggacggac cgaagtcaca tcctttcatt ttctttcttt aatttattag caagatagac
    37921 aatcagcagt agtaatacca gacttgtcat aatggaacct tctatgccaa aagaaccacc
    37981 tgataaccaa tcttgattgc cttgtggtaa aaaggtcatc agagacgttc ctgacggttg
    38041 accactaact aaaatcccaa agagattacc ctgagcaaaa ttccaagcac catgaatacc
    38101 tgcaacaccc caaactgtat cagttttgag aaggtaaaga gccatggcaa ctccgaataa
    38161 aaagagattt actagagata gaggggtgag gccagaattg cccatatgaa gcagggtaaa
    38221 gaacaggcta gatataagaa tagctagttt tagattggtt cttgaggcca attgaggaag
    38281 tagccaagca cgggccacca cttcttctgc tgtcccctgt aaaatccaaa atgggatagt
    38341 aaagacgaca aaggcaagag aataaggatt caagtgaatg gattccaaac gatattgacc
    38401 taagaccacc aaacctaaca aggtcagaag aaaaagtgcc agacctagac taaatccttt
    38461 cagaagattg ctgaggcaat tctctctata aaatcccaag gttcgaatag gtcttttctc
    38521 aacttttctt gtccatctga acacagtgtt aagaataaaa ccaaaggcca gtaatcctaa
    38581 aattaaacga aagtcacttg ttttatccgt caagctctga tgcaaggtct gcaagtaggt
    38641 tgcaagattt tgaccagcct ctccaaaatt tctagcaagt ccgatgagag ctaacaagcc
    38701 aataccatac aaagtaaaag ccacaaactc tcctatgaag acaaaaacaa aggctaacaa
    38761 ggggcttgtg taaatgttta aactcatttt tgaagcttgg aagtctttaa atattctttt
    38821 gttcttcata tccccgtcct cttttcttct atatatacta ttattatagc actttttaat
    38881 agcaattcaa gaaaaggaaa aaatcaatgt tatattttct gacacgaaaa atataaaaat
    38941 ttgccttttt ttactttttc tgatataatg agagaatatt cggaaaagga gactaaaaat
    39001 gaagaaaaaa tttctagcat ttttgctaat tttattccca attttctcat taggtattgc
    39061 caaagcagaa acgattaaga ttgtttctga taccgcctat gcaccttttg agtttaaaga
    39121 ttcagatcaa acttataaag gaattgatgt tgacattatt aacaaagtcg ctgagattaa
    39181 aggctggaac attcagatgt cctatcctgg atttgacgca gcagtcaatg cggttcaagc
    39241 tgggcaagcc gacgctatca tggcagggat gacaaagact aaagaacgtg aaaaagtctt
    39301 caccatgtct gatacttact atgatacaaa agttgtcatt gctactacaa agtcacacaa
    39361 aattagcaag tacgaccaat taactggcaa aaccgttggt gttaaaaacg gaactgccgc
    39421 tcaacgtttc cttgaaacaa tcaaagataa atacggcttt actattaaaa catttgacac
    39481 tggtgattta atgaacaaca gcttgagtgc tggtgccatc gatgccatga tggatgacaa
    39541 acctgttatc gaatatgcca ttaaccaagg tcaagacctc catattgaaa tggatggtga
    39601 agctgtagga agttttgctt tcggtgtgaa aaaaggaagt aaatacgagc acctggttac
    39661 tgaatttaac caagccttgg ctgaaatgaa aaaagatggt agtcttgata aaattatcaa
    39721 gaaatggact gcttcatcat cttcagcagt gccaactaca actactctcg caggattaaa
    39781 agctattcct gttaaggcta aatatatcat tgccagcgat tcttcttttg caccttttgt
    39841 tttccaaaat tcaagcaatc aatacactgg tattgatatg gaattgatta aggcaatcgc
    39901 taaagaccaa ggttttgaaa ttgaaatcac caaccctggt tttgatgctg ctatcagtgc
    39961 tgtccaagct ggtcaagccg atggtatcat cgctggtatg tctgtcacag atgctcgtaa
    40021 ggcaactttt gacttctcag aatcatacta cactgctaat accattcttg gtgtcaaaga
    40081 atcaagtaat attgcttctt atgaagatct aaaaggaaag acagtcggtg ttaaaaacgg
    40141 aactgcttct caaaccttcc taacagaaaa tcaaagcaaa tacggctaca aaatcaaaac
    40201 ctttgctgat ggttcttcaa tgtatgacag tttaaacact ggtgccattg atgccgttat
    40261 ggatgatgaa cctgttctca aatattctat cagccaaggt caaaaattga aaactccaat
    40321 ctctggaact ccaatcggtg aaacagcctt tgccgttaaa aaaggagcaa atccagaact
    40381 gattgaaatg ttcaacaacg gacttgcaaa ccttaaagca aacggtgaat tccaaaagat
    40441 tcttgacaaa tacctagcta gcgaatcttc aactgcttca acaagtactg ttgacgaaac
    40501 aacgctctgg ggcttgcttc aaaacaacta caaacaactc cttagcggtc ttggtatcac
    40561 tcttgctcta gctcttatct catttgctat tgccattgtc atcggaatta tcttcggtat
    40621 gtttagcgtt agcccataca aatctcttcg cgtcatctct gagattttcg ttgacgttat
    40681 tcgtggtatt ccattgatga ttcttgcagc cttcatcttc tggggaattc caaacttcat
    40741 cgagtctatc acaggccaac aaagcccaat taacgacttt gtagctggaa ccattgccct
    40801 ctcactcaat gcggctgctt atatcgctga aatcgttcgt ggtggtattc aggccgttcc
    40861 agttggccaa atggaagcca gccgaagctt gggtatctct tatggaaaaa ccatgcgtaa
    40921 gattatcttg ccacaagcaa ctaaattgat gttgccaaac tttgtcaacc aattcgttat
    40981 cgctcttaaa gatacaacta tcgtatctgc tatcggtttg gttgaactct tccaaactgg
    41041 taagattatc attgctcgta actaccaaag tttcaagatg tatgcaatcc ttgctatctt
    41101 ctatcttgta attatcacac ttttgactag actagcgaaa cgcttagaaa agaggattcg
    41161 ttaatggcaa aattaaaaat tgatgtaaat gatttacaca agcactatgg aaaaaatgaa
    41221 gtcctaaaag gaattacgac taagttctat gaaggagatg ttgtttgtat catcggtcct
    41281 tcaggttctg gtaagtcaac tttcctccgt agcctcaatc ttttagaaga agtcactagc
    41341 ggtcacatca ctgtgaacgg ctatgattta actgaaaaaa caaccaatgt tgaccacgtc
    41401 cgtgaaaata tcggcatggt attccaacac ttcaacctct tccctcatat gtctgtattg
    41461 gacaacatca cctttgctcc tattgagcac aagttgatga ctaaggaaga agctgagaaa
    41521 ttgggaatgg agttgcttga aaaggttgga ctagcagata aagctaatgc caatccagat
    41581 agcctatcag gtggtcaaaa acaacgtgtg gccatagctc gtggcctagc aatgaatcca
    41641 gacatcatgc tcttcgatga accaacttct gcccttgacc ctgagatggt tggagacgta
    41701 cttaacgtta tgaaggaatt ggctgagcaa ggcatgacca tgattatcgt aacccatgag
    41761 atgggatttg ctcgtcaggt tgccaaccgc gttatcttta ctgcagatgg cgagttcctt
    41821 gaagacggaa cacctgacca aatctttgat aacccacaac accctcgtct gaaagagttc
    41881 ttagataagg tcttaaacgt ctaaactcaa actgtaagga tttccttgca gtttttctac
    41941 ctcgtattgg aatttttgat ttttcggaaa attatgttag aattaagttt atgaaatgag
    42001 gtttcctcat acctagcaag actaggaata aaaatagaaa ttaggtagct agatgtcatc
    42061 taaggttatt gttacaattt tcggtgcgag tggagacctg gctaaacgca agctctaccc
    42121 ttcccttttt agactatata aatccggcaa tctttccaag cactttgccg ttattggaac
    42181 tgcccgtaga ccttggagta aggaatattt tgaatctgta gttgtcgagt ccatccttga
    42241 tttggcagat agtaccgagc aagcccaaga atttgctagc cacttctact atcaaagcca
    42301 tgatgtcaat gattcggaac attatattgc tttgcgtcaa ttacaagctg agcttaatga
    42361 aaaataccaa gctgaacaca ataagctctt cttcttgtct atggcacctc agttctttgg
    42421 aaccattgcc aaacacctca aatctgaaaa cattgtcgat ggcaaaggtt ttgagcgctt
    42481 gatcgttgaa aaaccatttg gtacagatta cgcaactgca aacaagttga atgacgaact
    42541 cctagcaaca tttgacgaag aacaaatttt ccgtatcgac cattatcttg gtaaggaaat
    42601 gatccaaagc atctttgcag ttcgctttgc aaacttgatt tttgaaaacg tttggaacaa
    42661 ggattttatc gacaatgttc aaattacctt tgcggagcgc ttgggtgtag aagaacgtgg
    42721 tggctactat gaccaatccg gtgccctccg tgacatggtc caaaaccaca ctctacaact
    42781 tctttcgctc ctcgccatgg acaaaccagc aagcttcaca aaagacgaga ttcgtgctga
    42841 aaagattaag gtctttaaaa acctctatca tccaactgat gaagaactca aagaacactt
    42901 tatccgtggg caataccgct ctggtaagat tgatggcatg aaatacatct cttatcgtag
    42961 cgagccaaat gtgaatccag aatcaacaac tgaaaccttt acatctggtg ccttctttgt
    43021 agacagcgat cgattccgtg gtgttccttt ctttttccgt acaggtaaac gactgactga
    43081 aaaaggaact catgtcaaca tcgtctttaa acaaatggat tctatctttg gagaaccact
    43141 tgctccaaat attttgacca tctatattca accaacagaa ggcttctctc ttagcctaaa
    43201 tgggaagcaa gtaggagaag aatttaactt ggctcctaac tcacttgatt accgtacaga
    43261 tgcgactgca actggtactt ctccagaacc atacgaaaaa ttgatttatg atgtcctaaa
    43321 taacaactca actaacttta gccactggga tgaagtttgt gcgtcatgga agttgattga
    43381 ccgtattgaa aagctctggg ctgaaaatgg tgccccactt catgactata aagctggaag
    43441 catgggacct caagccagct ttgacctact taaaaaattc ggtgccaaat ggacttggca
    43501 accagatatc acctatcgtc aagatggtcg cttagaataa aaaaatttcc tgcaagttta
    43561 tgccttgcag gatttttgct tctgattaga ttaaaccttc caagagacct ttcataaagt
    43621 tttctgagtt aaactctcca atatcatcga ttttttcacc aaaaccaatc aattttacag
    43681 gaatattgag ttcttcacga atggctagaa ccacacctcc tcgagcagtt ccatcaatct
    43741 tagtcaaaac aattcccgtt aaaggtgtga ttttcgaaaa ttctttggcc tgtactaggg
    43801 cattttgacc tgttgatgca tcaagtgcca agaaggtttc atgtggtgct tctggcacaa
    43861 cacgtttgat aatacgacca atcttttcca actcagccat aaggttatcc ttattttgca
    43921 gacgaccagc agtatcaatc atgagaatat cgataccttc agccacggca cgttccatac
    43981 catcaaagac cacgctggct ggatcagctt tttcaggtcc agttactact ggaacatcta
    44041 ctcgtcggcc ccattcagct agctgagcta ctgcacccgc acggaaggta tctgctgcaa
    44101 ccagcatgac cttcttacca gcttgtttgt agcggtgggc tagttttccg atagaagttg
    44161 ttttcccaac accattcaca ccaacaaaga gcataactgt caagttatct tggaagtgga
    44221 tgctttcatc gtagctacca tccttttcat aaagctcaac caatttctca atgatgacac
    44281 gacgaagtgc atcaggtttc ttggcatttt caagcttggc ttcgtaacgt agttcctccg
    44341 ttaagttaga agcgacttgg acaccaacat cactcataat cagcagttct tccagttcct
    44401 cgaaaaattc ttcgtcaaca gagcggaagt tagcaaagaa ggcattcaag cgggcaccga
    44461 aacctgtacg agttttctta agactgcggt catatttttc ctgaacggtt tcttctgctt
    44521 gaggcctttc tggttcaaga acttcagaat tattttcttc tatagtctct agaaactcag
    44581 tattcccttc ttctgagtgt ggaaattctt cgacttcttt ttgagaaact tctacaactg
    44641 gctctaaatc cagactttct tcaactgtgt cttggatttc ctcttcttgg aacacagctt
    44701 gttcaacaat ttcaacctct gcttcttcct gagaaatttc ctcaacttct gtgaaggtag
    44761 gatcaacatc ttcagacaaa tcaagatttt ccagagcttc ttttacaact tcttcgattt
    44821 taggttcttc tttttttccg aatagacggt caaacaatcc catatcttag ttctccttta
    44881 gcacatattc ttcgatagcc caggcgacag cttcctcatc gttggtcatc ggcgtcacta
    44941 catttgcggc tgcctttact tcaggaacag cgttttgcat agcaacacca agacctgccc
    45001 attcaatcat agagaggtca ttggcctcgt caccacaagc catcacttga ctttggtcga
    45061 ttccaagatg gctgattagt tttgccaaac ctgttgcttt atgaacattc tttggtgacc
    45121 attctagcaa catttcacgt gatttaaaga tttcatattg gtcaaacaat tctggagaaa
    45181 tcttctgaat ggctgcatcc aagggttctt gagcaaaggc agtcacgcat ttgttgtagg
    45241 tcatttgact agataagtct tcaaagtcca ctggaacaaa ggtcaaagct ggattgaatt
    45301 tggcataaag actttcttgg tccgattgga tttgataaac tgttccttct gagatggcat
    45361 caagaggcag tgataatttc tctgtttctt catacaaacg tgccacatca tcatatgaaa
    45421 agactgtttt atcaaggatt tctcctgtat ttttctgaac taatccacca ttaaaagtaa
    45481 tggtatactc atcttcctga ccgtcagtcc ctaactcatg gagaaagaaa tccatggctt
    45541 ttaagggacg accagttgtc aatacgacct tgataccacg atcacgcgca gctttcaagg
    45601 tttccttggt acgatccgtc agccttttat cagtagtcag caaggtcccg tccaagtcca
    45661 atgcaatcaa ttttatatct gccattataa gccctccata taagctataa ccgaccgttc
    45721 cttatggtga ccaatcacag tctttgctaa ttctaaaatt tcaggtcgtg cattttcagg
    45781 agctacagga tgtcccacaa cctgcatcat atgtaagtca ttaagattgt ctccaaaagc
    45841 catgacctga tccattgtga taccaagttt tttagctaat tcaacaatag ctacaccctt
    45901 atcgacatag tccagaacaa tatcaataga ttcaaagcca gttgtcatgg ccttaacacc
    45961 agggacatgt tcattaaccc aagcttcacc agcttctagc gtttcttctg tgaagttggt
    46021 tgtaaatttg aaaatgtcat ctgtgatatc ttccaaactc gctacttttt ggatattttc
    46081 attataatgc tgactcactt tcaaataggt ctcatcaacc gtatctagaa catatgaacc
    46141 cttcttaccc gtcaagagca gtttattgat atctacataa ggtgacgttt tcagcttttc
    46201 aaaagttgcc agataaaagt cacgagacat agtcgcttca tacaagtcct gaccttgata
    46261 ctctaccaaa ctgccatttt ccgcgatgaa aataatgtca tcacgaacat cagcaaataa
    46321 tttttccaga gacagaaatc cccgacccga agccaccgca aagtaaatcc ctttttcctt
    46381 gtaggaagcc aagagagact tgagacgatc catatcaaag cgtccattcc catctaggaa
    46441 ggttccgtcc atatccgttg ctactagttt aattgtcatc cttcaatact ttctaaatct
    46501 tttaacttaa ctgaaacaat ctttgaaaca cccgattctt gcatggtcac tccatagatg
    46561 gaatcagccg ctgccatggt tcccttacgg tgggttacaa cgataaactg gctgtccttg
    46621 tcaaagcggt tgaggtaatc cccaaaacgt ttaacattgg cttcatccag cgcagcttcc
    46681 acctcatcca agatgacaaa aggaatggtc ttgacacgaa taatggagaa aagcaaggca
    46741 agagccgata gagctttttc accaccactc atgaggttaa gcgactggat tttcttacct
    46801 ggaggttgaa cagaaatctc cacaccagct gttaaaaggt cgccctcagt caatatcaag
    46861 tctgcctgac ctccgccaaa catctgcttg aaggtcactt taaaggactc acgaatagct
    46921 tcaaaggttg atttaaagcg ttccttgacc tcatcattca tctctgtaat ggtttcaagg
    46981 agcagatttt tcgctgacaa aatatcatct cgctgactat ttagaaagtc cagacggttg
    47041 tgaacttctt cgtactggtc aatagcttcc aagttgacag gtcccaatga gcgaatagcc
    47101 ttctctaaat cctgcacctc ttgctctgcc agattgaggt tttccaattc atgtgccttt
    47161 tctagtgctt cagtatagct aatctggtac tggtctgtta attgattttg tagatggcgc
    47221 aagcgctcgc tgaccttttc tttcttggct tcagcacgtg tttgcttgcg aatccactcc
    47281 tcattctgct ggcgagcttg atccaagtga ctggcaatat catccagttg accttctata
    47341 tcatccaact caaactgctt gcgaatcaaa ccttgttgga gatttgtttt ctgagttttg
    47401 gattcttccg cctgttgact gagcaattct gtatcaacct tctcaagatt gtcaactttt
    47461 tcttggagca tgcgctgaat ttcttcttgt tcgatattaa gattgtccaa ttccttgcct
    47521 aaacgctcaa tatcagctac ttcataacgt ttttgccctt gcagttctgt cttaagcaag
    47581 cgagcttgcg ccacctcttc ctgcaaattt tgatagcgtt cttggatggc gtttttatta
    47641 gacttaattt cttcaatctc agcttccaga ttttgctttt cactggcgat agtagcaagg
    47701 ctctcttgac atttttcctt atccgcttgc caatctccct cagaaagacg atctatttcc
    47761 tcttcttgga gtttccaaag agtttccagt tcttcaactt gctgactagt ttgctgataa
    47821 gcgagggaca agccttgctc ctgaatacgt gcctgctctc cttgagattt gatggcttct
    47881 aatctttctg tcaatgcagc catctggtct tgcaaggtct tcaaagccgc ttcttctgaa
    47941 cccaagcttg cttcatctgc agcaatttct ttttgtaatt gctccagttc tggcttgatg
    48001 aaaatactgt tattttggcg attggcacca cccgcatagg aaccacccgt gcgtaattct
    48061 gtcccatcca atgtcaccat acgaacctga taacgaactt gtcgagcagc ttcacgcgca
    48121 tgttctacgg tatcaaagat agccgtcgta gctagcaagt tcttgaaaat ggcttccagt
    48181 ctagtatcaa aagtcaccaa ctcatctgcc atcccaagga aacctgggct tacagcgata
    48241 gcatcttggt tctgactaga aatcgtacgc gccttaatag tggtcaaagg aagaaaggtt
    48301 gcacgaccga ctctgtttcg tttgaggaaa tcaatagctt tggttgccga ctcttcatct
    48361 tctacgatga tatgctggct acttgcccct aaggcaatct ctagggcagt ttgataataa
    48421 acatcaaagg tcagatgctc actgactgca ccaataatcc cacctaggcg atctttttct
    48481 tggagaacac tcttaacacc tgcataaaag ttactatgat ttctcaggat attttccaaa
    48541 ctttgagctc tggcctgctt gtttttgaga ctatccagac ggtcaaagag ttgactttgt
    48601 tgagcttgat aggaagtttt ctgctcctct tgctccttgg caatagcttg atagtcagcc
    48661 aataatttct gaacctgcac cttggcagtt tcaagctcgt ctttttgctg actagccttc
    48721 tttttagctg tagctaattg ctctttcagc ttttctagtt gatctgcttg tttttgagaa
    48781 agctgacgac tattttccaa ctcattctca atacgggtca actggtttga gacatccgct
    48841 tcttcttgta aaagagctac aaagcgttca cgtaagagct caatcatctg atcaggatcg
    48901 tctgagaaag ccagcaattc agcttctaaa cgattgagtt tttgattatt ttggactaga
    48961 tttccctcta acagagctaa agagctttct ttatcatact tttctttgct gagtgaattt
    49021 ctcttatcct ccaaagcagc caaacgagct tgtgcctcct gttgattcag ggccacttgc
    49081 tcggactcca gtttcgatag ggctaatttt ctttctaaat cactaatcag actagtcaag
    49141 tccatcaaac tgccttggtc tttggccatt tcagcctgta aatcttggcg ttgcttttta
    49201 agagtttgat tttcttcttc taatttttca cgcttttggt aataactcat caagagttct
    49261 tgaacctgag ccaactcttc ttctgtcgac tctagttctg ccttattttc cttgatttga
    49321 gcaaccagaa cgtctaaata aatagcctta cgttgtcctt ccaagtctaa aaacttacgg
    49381 gcattctcag cttgcttctc aagaggcttg atttgattat ccaactcgta gataatgtcc
    49441 tctaagcggt ccagattatc ctgagtttgc tgcagtttac tctcggtttc ttttctgcga
    49501 gtcttgtatt ttaaaactcc agcagcttct tcaaaaatag ctcgtcgttc ctcaggcttg
    49561 gaattaaaaa tctcctcaac cttcccttgg gaaataatag agaaggaatc tcgtcccaat
    49621 ccagtatcca agaagaggtc atgaatatca cgcagacgga ctttcttgcc gtcaatcttg
    49681 tattcgctat ctccactacg atagatatgg cgttccaccc tgatttcttg acctgcatcc
    49741 ttgataaatc cgtcatgatt atccagagtc acaactacag aagcataatt gagcggtttg
    49801 cgactttctg ttccagcaaa gatgacatcc ggcatcttgc ccccacggag actcttgaca
    49861 ctagactccc ccaaagccca acgcagactt tctgtaatat tggactttcc agatccattg
    49921 ggtccaacaa ctgccgtcac accttggtca aaaacgacct tggtcttatc agcaaaagac
    49981 ttgaacccct gaatttcgat ttcctttaaa tacatgaatc cagccctttc tcaacggcat
    50041 ttttggcagc ttcctgctct gctaatttct tagaacgacc ttggccttga ccgatgctct
    50101 taccttcaac aagaacttct acatcaaaga ccttatcgtg agcaggccct gtttcagaaa
    50161 tcacttgata acgaatagcc acatcaccat tgacctgaag caactcttgg agatgggttt
    50221 tatagtctgt aatcatctca aattcgcctg cttctacctt aggaatcata acttggtaga
    50281 taaattcctt gacctttgcc acatccttat ccaaaagaag ggcaccaaga aaggcttcaa
    50341 aggcatcacc aagaatggtg tcacgattgc gaccaccaga tttttcttcc cctttaccca
    50401 acttgataaa ctggtcaaac tggcaatcac gcgcaaaacc agctaaactc tcctcacgga
    50461 caatcatagc acggagtttt gataggtcac cttcaggctt tttaggatat tttttatata
    50521 gatattctga aatcaataac tgtagaacag cgtctcctaa aaattccaag cgttcattgt
    50581 gtgaaatttt taagaggcgg tgctcattgg cataactcgt atgagtaaag gcagtttcca
    50641 gtaacttttt gtctgcaaat tcgatttcaa aatgattctt tagtacagtt tgtaattctt
    50701 tcataccaac ttctttctaa ctgataatag tcctttttat tatatcaaaa aaagccccct
    50761 gagtcactct aaaacgggac tggaaagcat ttgggaattc tttagacaga gattctcagt
    50821 tttagcggca aatttgggtc aggataaaga aaaaagccct attaaaggct ttttaggatg
    50881 tttacatcca ccctgaggga atcgaacccc catctcaaga accggaatct tacgtgatat
    50941 ccattacact aagggtggaa acttgtttta ttataacaga aatttgctct aataacaagt
    51001 tttttggtca aagaccccgt cttagtggga agcatcccca ttccagatgg agtttttcac
    51061 gatcacataa tcaacgtgtt taaggtcagc aacctgacgt ccacctgcat aagaaatagc
    51121 actttgaagg tcttgttcca tctcagttaa agtgtcttgc agatgacctt tagcaggaag
    51181 caagatacgt ttgccttcca catttttgta agcacctttc tgatattgtg aggctgaacc
    51241 ataatattct ttgaactgtt caccatcgac ttcaatcgtt ttccctggac tttcaatgtg
    51301 tcctgcaaag agggaaccaa tcatgatcat gctagcaccg aagcggatag acttggcaat
    51361 atcaccgtga gtacgaattc ctccatcagc gataatcggt ttacgcgcag ccttggcaca
    51421 ccagcgtaga gcagccaact gccaaccacc tgtaccaaaa ccagtcttaa ccttggtgat
    51481 acaaacctta ccaggaccga ttccgacctt agtagcatct gcaccagcat tttccaattc
    51541 acgcacagct tctggtgttc ccacatttcc agcaatgaca aaggtatctg gcaattcttt
    51601 cttgatgtgt tgaatcatag aaatcacgct ctccgcatga ccatgagcaa tatcaatagt
    51661 gatatactca ggagcatcag ccttgagctg gctaacaaaa tcatactcat aatccttaac
    51721 accgacagat atggaagcaa tgagcccttg atcgtgcatt cgtttaataa aaggaatgcg
    51781 tcctgcctca tcaaaacggt gcataatgta gaagtaacca cctttagcca gttgctctgc
    51841 tacattttca tccaaaatcg tctgcatatt cgctggcaca acaggtagtt taaaggtgtg
    51901 atttcctaaa gtgacacttg tatccgcttc tgcacggctt ttaatgacac atttatttgg
    51961 aatcaattga atatcttcgt aatcaaaaat tggaaattca tttaacatat cgatgtctcg
    52021 tttcttttgt aatgacctac ctatgctctc gcatcactac gccttttccg acgtttcctt
    52081 aatttattat aaaccaaagt acagtttttg tcaaattatt ttatgaatta aaatatattg
    52141 ttcggatttt gcttgtgtta aaaataaaag aaagagggga aattattttc tccccacttc
    52201 ttcatcaata atcgctttaa aattttcttc tgaattttcc atcattttac aaaatgcact
    52261 ataagatgaa gacttctgag gaatttggat agaccatttc ttcaacaaag ctccataacc
    52321 tgctaggttt cctatctcat tatcaatgac cttgtccttg ctcggaaaaa caagtccagc
    52381 cttctcagct tttaaaatat aagaatagga aatcagctgg aataagtcct cacggttgat
    52441 tcctttttca gtcaattcca gttttttata ttttgcatct agaacaatct ttcgttctct
    52501 gtcataaaaa tctggatata cttttcgttt cccaacagaa aatactgaaa ttccatccgt
    52561 cttatcctta tttctgggat gtacaaaacc ttttggcaac aaggtgtaaa catactcttc
    52621 ccaaagccag gcaacatcaa agagaatacc atagattttt tgatcttgat accctaaacc
    52681 gtgcttttct tggtttagga tcatcagaca aagttcttgt aagtttctgt actcgtgaaa
    52741 gtatgcatga cgtataggtt tagattgatt tctccgagta atcttagcac gatcagctag
    52801 tttataagag ggcgttacac gcacgatttc agatacgttt tcacgactag ttgagagatt
    52861 atctagtacc ccttgaccaa tgcttttctg attcttaatg tattcaatag tgtgacggac
    52921 caactgcatg aggggattat cataggtgaa ctctctcgtt gtgtaggcaa tatttcccgt
    52981 gaaaggaaga tttttcttga gatggtttct tacaacaatc actcccttaa cattactgtc
    53041 gttatgagaa aatcgatgat attccttata aagacctttt cgaatagcag cttgtagata
    53101 cttggggaag agatacatca aaagttgata aagcctctct tcacgagaca aagcaacatc
    53161 taaactagtg agattgatat aaagaacctt gtttaagaga taatgcaaaa aatggtcatt
    53221 actctcatca gaaaatcgtg aggaaatcgt taatctttcc tgaccatatc caagaaaacc
    53281 aatcacgttc cctgtcttga ttttctgatt gactgtttca aaaatctttt gatccttatc
    53341 caaatcagga gtatgagtca aatcatttgg aaaaatgaaa atacgttcat cttgggatag
    53401 actttccaag gttctgtcta aaagaagatt gcttagttta ggatattctt caacaaattt
    53461 ttctttaata atcttgtgtt gattatcagt aatccgcatc atcgttttca tcaccttcat
    53521 tgtcatcagc tactgcctga tctttttgct cattatttgt cagttcaaat gcttttttca
    53581 aagtttccaa agtttcaacc tcatcataag aacctcgcaa gtagtcttct aggagaggct
    53641 taatataatc agaccagagt aattcatagt caaaatctac atccttcaac ttaagaaaat
    53701 aacttggtcc aatatgataa tgactgttta attcctgaac attttcgata gcagcgttca
    53761 agtttcttag acgaattttt gcttcttctg catggatatt cagctcttta tccaacatgc
    53821 caacttgacc ctcggcagta acttcaacaa aacgaaaacg acgacgcata gcaaaatcaa
    53881 aggtatccac tgaacgatca atatcattca tagttccgat gatgtaaaca ttttcgggga
    53941 tatagaactt ttcatcagtt tcgtgtagat ttgcatattg ggtagaaaca cttccttttt
    54001 caccacgata gccagggtcg atagaaaaaa agagttcgcc aaaaatctta gaaatctccc
    54061 cacgattgat ctcatcgatg atgaaaacaa atttcttgtc tgtttcaacc tcttctggag
    54121 aaatatagtc tttcaaacca aatctctttc tcaatgtttc taggacagtt tttccaccac
    54181 ttttgtagta ttcttgctta ttataatttt tatctttata caactcgtaa acatatttgc
    54241 taggtagtga ccatcctgga acaccactat cataatttac tgacaaattt tgtctactat
    54301 taacagataa gtaagatgtt tttgttatat attctttttc ttcagcaaca tttatatatt
    54361 ctaagtaaga atcccaagcc tcatcaaaat tatcttgtcc tccaatcaat tgggtttctt
    54421 ttgctttctg acaaaaatct ttaaaaatac cgtcctgtag cctaaactca atagctccat
    54481 ccccatttga tactggtctt aaaccttcta caaaatccgt ataatcatag gatgggtgaa
    54541 attgtacaaa tccgatttgg tcttcgttac catccgttaa ttctttggca atttctttag
    54601 caagataagt ctttcctgtg ccaggagcac cacgaaggat aaggtttgga gactttaata
    54661 gagattgagt taattgatga ctaaaattgt ttgatgaatc cattgtacta ttgtcttcct
    54721 tattttccat aaaaagctta gaatactcaa aaagcatagt tcctaatttc gatggctcca
    54781 actcaggata agttttggac accagttcaa ttattttatg attttgcaga taaggtccac
    54841 cttgatttgt ctgagaaaca aagtggttcc aaaattcttt ctgactatta atatttacac
    54901 caaagaaagg atctccctca gtatagatac aaagtaattt tgtcaccata gcagaacgac
    54961 caataaattc atttgttgat cttttcatat caaaaatagg attttcaaag ttaaaacgaa
    55021 taccttcttt gataatttca tacaaatctg attttaattt tgaaaatcgc tgatccaact
    55081 ctgaaatctc attattagct tgatctttat atttgtttgt ttttttattc caataaatac
    55141 caaattttga agctgagcca ccagaaattc caagaaatag atttttgtat tttcccttct
    55201 caagagcgta gcataaagac ttattttgct gtccctttcc tattacatat tcatcgattg
    55261 acattgttaa aatcctatcc aaaggccatt cctggagaaa ctcttctttt aatttatcat
    55321 taaacttttc accaacagtt gccttattta ataactcttc tttatttaga ctataccatt
    55381 tataaaaatc ttctaaacta acttttcttt tattcatcaa tctaactcct tttactaatg
    55441 atgtttaaat attggcatta cttattaaca tatattttct acatagaata ccatatccta
    55501 tagaaaaaga aaagaaattc taaacaaaag cccagtgtta ggagctttaa tatctcataa
    55561 cactagactt cttctctatc ctaataatac tcaacctgac ggtagtccca tgagttaaaa
    55621 gtatctgaca ggtgcatcat gattttatca atgtcaagcc ctttacggat cacaactgga
    55681 gctggtgaag ttgaacgtgc tcctccttgt tctgggatga gtttgccgtc cttatcgacc
    55741 atagacacca ttacaccttg ctcatagcga gtttcaatcg ttttgtcatt gaagcagatg
    55801 aggcgtagac cattttacct tcttcccaaa gcttggcagc caattgttca cctgcttttc
    55861 caaacttgat aacaaaacag ctagtaccac gtacatcagt aataagttct tcacggccat
    55921 ccccgtatgc tttgagtttt tcaaaggctt ctggtttcca aggaaggata caaccaagaa
    55981 gaatatcttc atcccaatgt ttttagtaga atgcttcaat ttctgggttg agttgcgcta
    56041 aagcgcaaag ttcatccatg ctaccgcaga gaacaacacc tggtttgtta cgcttacgtt
    56101 ctttggctgc gaacttacgc tcaagtcctg ccttgtcact ggtcatgata atgtaaccaa
    56161 ctttagtagg gcaaacgata catccgccct caccttttaa aatgtcgtag ccttcttgtg
    56221 aatgtgtttt gtcataattt tataatgtgt tgaatccaga atagtccact gtagtttcta
    56281 aaaaattgct ggaaatggat gttaagctcc aattcatttg tttacatctt atttcagttt
    56341 actatatctc cttttctatt ttttctaatc ctgccagtag gctggtcgtt gtttttcata
    56401 agcagcaatc aactcttcat actgcaaggt aataccgata tcatccaaac tatttaggag
    56461 tttatgtttc cactcgctat ctatctcgaa ggtgaattct tcaactggtg agatgatttt
    56521 ttgttgttcc aagtccacag ttacctggtc ggttggtttt agctgggcta gtttctctct
    56581 aacctctcta ggctgaacga ttggcaacat gccattattg agttcattat tgtaatgaat
    56641 gtcaccgaaa gatcctgcaa tcacgacctt aaaaccatag tccgctagag cccaagcagc
    56701 gtattccctc gaagaccctg ccatccatta cctccaaata aaatataagg ctactagtgt
    56761 ggtcaccatc ccaagaaacc aaactatttt aaagtaccat tttcgagtct tgtggtgaaa
    56821 gatgattcct gctagccagg caccaaaacc accaaaagta aaggctaaaa taagtaagat
    56881 tttctcaggg atgcgccaaa ctcttctcct tgccttagat ttgtcaatac cataaatcaa
    56941 gaaaatgatg acattccaaa tcaaaaggac tagagtaatt ttttcgtcta acttcataac
    57001 cttgcaataa tagcttccgt catttccttt gttgaagcct gacctcctat atctctcgtt
    57061 aaaattcctg ccgccagact tgtctcaaca gcacgtttga tacgctctgc atcctcataa
    57121 cgtccgaaac tatctctcaa catcatggaa actgataaaa tcatggaaat aggattggca
    57181 attccttgac ctgcaatatc aggtgctgaa ctgtgaatag gttcatagag acttggtcca
    57241 ttttcagaat gactggctga tggcataacc ccaagtgtac cagataagac gcttgattca
    57301 tcagataaaa tatctccaaa aagattctcc gttacaataa catcaaactt agcaggattg
    57361 gtaatcataa gcatagcagc tgagtctacc agctgatgtt ccaaggttac atctgggaaa
    57421 tcctgtgcga cttcctcagc tactttccgc cagagttttg aggtcgctag aacattttgc
    57481 ttatcgatac tagtaacgat ttttctgcga tttcttgcaa tttcaaaggc tttgcgaata
    57541 atccgctcca cttcctcata gctatagtcg ttgatatcac gcgcattgcg ctcttcaaga
    57601 atatgatctc caaagtaaat cccgcctgtc aattcacgca ccacgacaaa gtctacacca
    57661 gcaattcgtt ccagtttgag tagtgacaaa tgcttgagac tgtcaaagat ttttacagga
    57721 cgaatattag cgtaaagatt gagttcctta cggagagcca tcaggccttg ttcagggcga
    57781 accactgctc catcatactg aggactaccg atagctacta gtaggatagc atctgcttcc
    57841 ctacttgcct taagggtttc atcaggtaag ggaggtcatg ctgcatcaat atctgcacct
    57901 ccgaacggtc gtctgtcaat ctcatagtca aaacctgttt tttcagctag agcctccaga
    57961 acttctaaac caacctccat gatttctggg ccaattccgt ctcctgctag agctactatt
    58021 ttctttgcca tagccttctc ctttacacac taggcatatc gtggtaagaa acactgcgtc
    58081 ccatctcacc tgcattctct ttttgaacaa aggtattagc gtttatatag acaatagcag
    58141 aagccttcaa cacatcaaaa tcaagccctg ctgcattaaa gatggtttct gtatctctgt
    58201 tttcaacagt gaccaaaacc cgatcctggg tatcgattcc atctgttacc gcatcgatag
    58261 tgtaggacac caaacgaaca gattggttaa agaacttatc gatagcatta aagattgctt
    58321 caacggaacc ttgccctgtc gcattaaatt cgactttctc accatccata ttggctaggc
    58381 taacgagcgc ttcaatgtca ttatctgcat gagtttgaag ttgtaaatca tcaaagtgga
    58441 agccttctgg attttcaacc atggttccag ctaccaaagc tcgaatatct gcatctgtga
    58501 tttcttgctt cttatcgacc agtgccttga acttagcaaa gagtggtttg atatcctctt
    58561 ctgtaaaatc tagggccaat tctctcagtt tctcaacaaa agcatggcga ccagataatt
    58621 ttccaagcag aatcttaaca ccaaccaatt caggtgtgat gatctcataa gtgagaggat
    58681 ttttaaggac tccatcttgg tgaataccag attcgtggga gaaggtattg ccaccaacga
    58741 cggctttgtt tttaggaact ggaataccag agaagcgaga aaccatttct gacgtattga
    58801 tggtctcatt taggacaata ctggtttcta cttggtagta atcttggcga atattgagag
    58861 ccactgcaat ttcttccaaa gcagcatttt cagctcgctc cctaatacca ttgatagtcc
    58921 cttcaacacg tcctgcacca ttcttgacag cagcaaggct atttgccact gccattccga
    58981 ggtcatcatg acagtgaggc gaatagatga tctgacgatc cgtcttgaca ttctcaatca
    59041 ggtatttgaa gatggcacca tattcctcta gtgtggtaaa tcctatattt tctaaaaatc
    59101 tcttcagtaa agaatattta gctaattgaa agttcatgaa aattattaaa atatttcatt
    59161 ttttagaggt taagttccaa cttttttcta tcaattccag tacttcttca tctgataaag
    59221 tatcatcaag ggacacacta atccagtagc gcttgctcat atggaaggct ggataaatcc
    59281 ccttttgtga aagcaaatta gctacttggt catgcttgag gttgactgct tccacttgtc
    59341 cttctctgcc cttttccagc ttattccaag agattttcat caagacggca taccactttt
    59401 gattgccttc atggcgcaat acagctgtat caggcgattt ttcccacaga tactccaact
    59461 ggtttccata cttttcctga acttgagtca tgatacgctt agtctgatga cagataaaat
    59521 cttgcacatc aaaacaagcc ttccgaatct ggtaaagaat ctccagacaa gcctcacgga
    59581 catttccgac aaaacttccc ctcatgcttt ccatataaac gtgaggatag aggtcaccag
    59641 tctcttggtc aaagacttga aagttcacat tatcagcagt gatggacaca gtcatgacaa
    59701 agtcaccttg caaaatctgg caactatatg tccagacttc gctattttct ataaaaccat
    59761 aatcatgagc cttttcttga ttaaattgat aggatttaaa aatttcaaac ataagtgaaa
    59821 actgctaccc aaagctagca gttcctttct attttttaaa aaacaacctt agtaccatgc
    59881 aattgtgtta cccccacctg gtcgataaag gtttgacggt tttcaaggtc aatcccccca
    59941 cctggtagaa tttcaatttt acctttagcg tactccaaaa ttctgtgata gtgaacaaaa
    60001 cgtttttcta aggagtcgcc agacacacca gcacgagtta ggatacgagt gacaccggct
    60061 tgactgagcc agtcaatagc ttccggttga tcttcatcac ttagttcatc aaaggccatg
    60121 tgaaagacaa tttccattcc ttttgatgca gcaattaact tttccagatt aggcttatcc
    60181 aactttttat cagcagttaa agctccaaat acaacccctt gacttccagc ctgagcagtc
    60241 aaacgaatgt cttctagcat gatagcaatt tctaggtcat tatagacaaa gtcaccacca
    60301 cgtggccgaa tcatggtcat gatggttgta tcgtagttag ctgccagttc agccgctgcc
    60361 ttagtcactc catagctggg tgttgtccca ccaactgcta gattatcaca gagttcaatc
    60421 cgacgagctc cagcctgcat cgctttttca agtaaagtca cattttcagc acaaaattcg
    60481 taaatcattt gattctcctt gaatattact tcaattttat tatatcatat tgttatgaat
    60541 atgctttcaa ttttatcaag gcaaataact actgttttaa ctattctttg tctggaatga
    60601 ccttgaagag ataataagta ataaagatgg tcaaagcacc cagaccgatt ttgactggta
    60661 aaagaggtgc aaaataaata gaaattccca tcaagacgta gatagagacg atgatttttt
    60721 tctttcgttc acgcgcaata gacttggtct cacgaaaatc agctacatat gcttgataga
    60781 gcttggtatg ataaagccaa tcttcgaatc gcttggaact tctggagaaa caagcaatag
    60841 acaacaaaag gaaaggtgtt gtcggcaaca agggtaaaac aaccccaaca atagccaagg
    60901 ccagtgataa aaaaccaatt atcagataga taagacgcat aacttctcct agttaatact
    60961 cttcgaaaat ctcttcaaac caggtcagct tccatcttca acctcaaagt agtgctttga
    61021 gcaacctgcg actagctttc taatttgctc tttgattctc attgagtata aaataatctt
    61081 cttctagttt cgcataaaat gatgtatttt gtcaagttct aaccaaaagg agcctgaaat
    61141 ttactttcgg gcccctcctc ttatttaatc ttttcttcct cgtagtcgcc tttgctacaa
    61201 acaacctgct tgccaccacc acggactttt ttctccatga ggaagttgcc acattttgga
    61261 cagtcacgac caacaggctt gtcccaagag gtaaattcac attctggata gcgattgcaa
    61321 ccatagaaga ggcgattacg cttggttttt cgctcaataa tttgtccctg atgacagctt
    61381 ggacactcaa caccaatctc tttcacgatt gcttgggtat gacggcaatc tgggaaattg
    61441 ctacaagcgt agaatttacc aaaacgacca agtttaatga ccattggact gccacacact
    61501 tcacagtcaa atccagctgg ttcatcctta atctggattt tttccatttc ttcttcagcc
    61561 ttggcaactt ctttagagaa tggtttgtaa aaggcatcaa tgacccgtcg ccactgctct
    61621 tttccaactt cgacatcatc cagtttacct tccatttcag ctgtgaaggt cacgtttacg
    61681 atatctggga aatattcaac gatgagctta ttgacaattt ctcccaactc tgtcggttca
    61741 aaacgtttgg ctgccaggcg aacataataa cgtttctgaa tggtttcaat ggttggcgca
    61801 taggttgatg gacgtccaac cccattttcc tctaaggttt taatcagtgt tgcttcagaa
    61861 taacgggcag gcggttgggt gaaatgttgc tctggtttgc tattgacctg tttgaccaca
    61921 tctccaacaa ccatgtccgg taacatctta ttcttgtcag aatcattata aatggcaaga
    61981 taaccatcaa acttaacctg actaccattg gcagcaaatt gaactccatt ttgagacaat
    62041 ttaacagcca tggtatcaaa aacggccgct gtcatctggc tagccacaaa acgattccag
    62101 ataagggtat atagcttgag ctgatccttg tccagatact tagcgatgct ttctggtgta
    62161 ttaaagacac ttgacggacg aatagcctca tgggcatcct gagcacctga tgcatttttg
    62221 accttgctac cgtgcttaga atacttacta ccaaaacgat ccgtaatgaa gcttgccgcc
    62281 ttattttgcg ctacaggact gatacgagtc gaatcggtac gcatataggt aatcaaacct
    62341 tgaacaccag aaccgatatt aattccttca tagagctgtt gggcaaccat catggttttt
    62401 cgagtacgga aattgatttt attggcagca tccatctgca tagatgaagt ggtatagggt
    62461 aaaggagcat tgcgcttgcg ctctttctta tccacctgat ctactgaaaa gtctttactc
    62521 gtcagacgag acaagacttc cttgacttcg tcattgctgg tcagtttcat ctttttacca
    62581 tctactccat agaaggaagc atgaaattgt ttggttccct ttttaaagac agcatcaact
    62641 gtccagtatt cttctggctg gaaggcattg atttcatttt cacggtcaat gatgagttta
    62701 agggcaatgg actgaacgcg acctgctgac aagcccttct tgaccttctt ccacaaaata
    62761 ggcgaaatcg aataccctac caagcgatcc aagatccgac gagcttgttg ggcatcgacc
    62821 aagtccatat cgatcttacg aggttcttta aaagcatttt tgactgcatc cttggtgatt
    62881 tcattgaaga ccacacggtt ggcatcattt tcatccaagt tgagaatatg ggccaaatgc
    62941 caagaaatcg cttctccttc acggtccggg tcactcgcga gaaaaacttt attagctttt
    63001 ttagcttctt ttttcaagtc attgataaga gggccttttc ctcggatatt gatatattgc
    63061 ggttcataat tattttcaat atcgacggac atactggatt tcttcaaatc acggatatgc
    63121 ccgacactgg ctaaaacctt gtagtttctg cctagatatt tttcaatcgt cttggcctta
    63181 gcaggcgact ccacgatgac tagatttttt ttaactgttg attttttctt ttttgttgcc
    63241 gtagccacag tatcacacct tttcaaagta ataaacttta taaagtgtaa accatttttt
    63301 gaaccctgtc aagacttagc tactataata gaagaaaagt tttatactta aaacctcagt
    63361 cttcctttga tatacataga agactcacga gaaaaaccag ctattctcaa gaaattattg
    63421 ctcctcagac tctgtataaa acttattagc tttttccttt tcttttgctt ccttatcctt
    63481 gatatactgg aagaaatact ccaccagttc ttccttacta agttgttctg aatcagacaa
    63541 ttgtgaaact tgaacagaaa catcacttaa accatagtca cctctcttac ttgaaatcat
    63601 atcgagttct tcttctgtca aataatttcc tgaaatggtt agctttaggg tatgagtctt
    63661 tttagaatag gtttttttca aaatattatg cccctgaaac tgctctgata taaatttctt
    63721 aagggactct tttttcaacg tttctctcac taaagtcgtt gcagagatga aactcggaat
    63781 catcagcaaa acagcaacta gaagcaaaat cctacgcatt ttagagtctt cttcattatc
    63841 tttaaaataa tgtttcttaa ccatcatcaa cctaacacct atataagtcg caatgacaat
    63901 aaagctacaa ttgatgagaa ataggtaaga ggagcctatg ataaatttta gattagcaga
    63961 agcaatagca taacctactg tacaaagagg aggcatcaag gcggttgcaa tagcaacacc
    64021 aggaacaata ttattggtct cttttttcct agcaccaata atacctgcta tccctcctac
    64081 aaaagcaatg agaacatccc aaatagtcgg agaggttcta gcaacaatct ccgaactagc
    64141 atacgaaatg ggagaaagat aaaaataaag tgttgaagct attagactgg caagaatttg
    64201 aatagctaat attttaaaag attttcttaa caatttaaaa tcaaatatag ctagagagag
    64261 ccccactccc agaataggtg tcatcaaagg agagattaac atggctccaa taatcacggg
    64321 agtcgaatcc atatttaatc cgatagaggc gataagcatg gcacatagta aaatcgctaa
    64381 atcacttctg gaaagttcta attcttcata tattttattt ctaaattcta tcaacgaata
    64441 cagtttatta tttgtcacaa atatcttcct ttcccagcta actagtcgct aaaatcctaa
    64501 caaactcaat actttagtag tctgatatgc caatctcacg agctcttttt atcattttcc
    64561 ataatatcct gactcaaatg tctactgata tctctcatca gtttcatttc tagtaaatga
    64621 aaatcaaact cggaagctaa ccgtagcttg ctcaaaacac agcaaggcaa agctgagctg
    64681 acgtaaaaag attttcgaaa agtatcatca tctatttcag accatttttt ataataacca
    64741 ttttattttt atttgtcaag gtctttgaat tctttcttaa acaagccttg taatctctac
    64801 ttttgaagaa tttatttttc cttactgaca agatttgaga cggtaggaat cattgaacat
    64861 aacctagcca acatcaatca caatcatttc tcctttctca attacactaa attatagtgt
    64921 attgaatcta taacagtgca ccttggctgc taaaatattt ctataaatca atttgacttt
    64981 cctgatagag ttgttcacat cttatttcaa ttcactatac tttcccttat actcaatgaa
    65041 aatcaaagcg caaactagga agctagccac aggttgctca aagcactgct ttgaggttgt
    65101 agataagact gacgaagtca gctcaaaata ctgttttgag gttgcagatg gaagctgacg
    65161 tagtttgaag agattttcga agagtattat atgagaaaaa tcctctactc tactaatcca
    65221 cttagaaaaa acgcatatta tcaagtgtta aaaacttgct aatatgcgtt ttattatgga
    65281 aatgttgggt tcattttctc ttaaaattga ttttttctta gaattctagc ttaggtcatt
    65341 tttaaaattc aaattccgca agaacatctt gcccactggt gaccaatttt gctccttctt
    65401 gaatcaaatg atggcaaccg tctgatagtc catctaaaat gctaccagga atagcaaaga
    65461 catcgcgtcc ttcttccatt gctcgctcac acgtaatgag actacctgaa cgcatcttag
    65521 cctctgctac aatcacacca cgacaaagtc cagcaatgat gcgattacgg gcaggaaaat
    65581 gaaatttcag aggttgttcg ccaggtccat attcacttag aaccagatgg tcattgccga
    65641 tgtagtcttg caagcgttta ttggctttag gataaaacac atccagtcct gttccaatca
    65701 ctgcaatggt ttttccgcca ttctgaagag ctgccatatg agctgctgtg tcaatgccct
    65761 tggccagacc actgacaata accagttcat tttccaagcc ttgaatgact ttttcaactg
    65821 atttagctcc ctgtttgcta caagcacgac tgcccacgac cgctaccttc gggaatttca
    65881 ggaggtcaag atttcccttg taaaataaaa gtacaggcgc atcatatatt tcactcaaat
    65941 cccaaggata acagtcatct aaaatagaga aagatggaaa tttttgaaac tctttcgaca
    66001 aatgcgcatc gtctatctga aaataacgtt ccataaaaac ggctggatta cggcaacctg
    66061 agatatctgc aatatcaccc aacaaaagct cctgatcaac attttcaccg tattctagca
    66121 ctttcaaaat ctgttgattg gtcaaacctg atttttttaa cttatagatt tcatagtttg
    66181 tgattttcat aaataactcc atttcttttt ctactcatct atctattcgt aaaaaatcaa
    66241 aaaacatccg actattttgt cagatgttgg aatctttaat tttcgttttt aagaatttct
    66301 tctaatttac gatagtcttg gacactatcg atctcataaa tgctattgcc ttctaattct
    66361 tcaacataga catctagctc tttgatatta tccttaacca tattgtccca gtagagatca
    66421 acaaattcac cacttgcata agccttgtcg ataaagctga caatcttttc tgcagttgga
    66481 gcatcccaga aggatacacc actaaggatg cgacctgcct tgctatcaac aataatgtct
    66541 tgaaccttgt agtcatctcc atagaccaag aaccattcgt tggtacaatc ttcacgataa
    66601 acactaaaat aagtcgaacg tgtcaaatca ttgcggaaca tatttttaaa gagataattg
    66661 tcagcatcaa taacatagct gttggccaat tcttctttta caagatagag agagtaaaag
    66721 ttattgtagt cagcgtattt atcattgaaa acgaggcgaa caccgtattt ttcttttaaa
    66781 taatcgaatt gttctttaag ataaccaacg atgatgatga tgtcattgat tcctttttct
    66841 ttgagaaact caatttggta ttcaatcaaa ggtttttgat taacctgaac caaggcttta
    66901 ggggtatttt cagtcatagg acgcaagcga gttcccaatc ccgctgctaa gataatggct
    66961 ttcacacgaa tctcctttat tctttaataa taatataaac tccagcaatg acgacaagtg
    67021 acgtcataat ggtcagcata tctaatgatg ttcccaagaa aagagctgcg aacaagacag
    67081 tccatactac atagctcacg ttcaagcctg tagccttggc tggttgcaag cgattgatag
    67141 cgatataata agccaaatag gaaatcatat caaaggctac aaagacaatc atgagaccta
    67201 gcaattgtcc attggctact gcaacaaatg actgatgaga gaagagcaca atcacaagat
    67261 aggacaagaa cgaagttact tgacggatta agagggcttc gatttcactc aattcacttt
    67321 ccatggcaaa agagctaaga acactctcac ttccccatgc aatagcacaa accaaagcac
    67381 aaagaatccc aatgtagaaa gaattaacct gttcaacctt ataggtctgg gcaataatcc
    67441 ctccaataat caagacaatc ccaaatacag tatttttcga aatcttgtgc ttcaaaaaga
    67501 agaaagccaa tagaactgaa atcgcagggt aaatagccga tacagatgaa gctaaagaac
    67561 ttccgatata cttaactgca taaagattgg cctgcatacc gatagggcct gctagcaagg
    67621 ctcctatgat aacactgaca ttgcgaatat ttaagaaaat tgagaggcga actttccctt
    67681 cttttaccaa gagaaaagct agtaagataa agatgctcaa aaaatcatga gttgcagcca
    67741 ccacaaaggg tgacaaatct gtaaaaatcg aaaagatata agcactaacc gttagaccca
    67801 agccccagaa aatacctgag agaaggccaa aaggaactcc gtttttactt ttcatctgaa
    67861 cctccataag aagccaaacc tttaatagct ctttggtaac gattcacacc atagtcacca
    67921 aaatcttcac cttgctcttc cttatagaca gtccatagac tccaaatagt atcttgtaaa
    67981 attttataaa tagcaatctt ttcatgagaa accggtgttt ggtcactctc atagtgagat
    68041 aagaaagttt cttcctcttg ggaagtgaat tcagactcta aaaagagggc agccaaatcc
    68101 cacattggat cattcattga tgaatattcc cagtcaatca aataaagtcg tccttgaggt
    68161 gattcgataa agttttcagg caccaaatcg atatgacaag attttctgtc aacacctaag
    68221 tcagccagtc ttttctctaa ggagaagact gcatttctaa cagattcata gttggcataa
    68281 ggaatttgtt cttcaatcaa ggattcgtat tttttgattt cttcaaaagg agcaaattct
    68341 cctcttaatt ccttagcaga cgtatgaata gtttgtaata ttggagtaat tttgtcgaac
    68401 ttggtcttga ttgacgttga atcaagcgta atcgcagatt cgatatactc atttactttg
    68461 ataccagctt caatatcaaa aagataattt tttacatcta agcctaaatc ctttagtagt
    68521 tcaagattgt acttttcatc ttgtcgattg ataagctttt ctgtcccttt accaaagaat
    68581 ttaacaatgt attgcttatt tgttgttttg gccaaatagt tttgattggt cattccaccc
    68641 agttgttcaa cactgaggac ttcctcttct tgactaagta aggaagaaat tttttcttta
    68701 atgattttct ccacaattaa cctccagtac ttatacttcc cacttaaaca ctgttttaaa
    68761 ggctgtgttt aaatcggttg caaagacacg atgaatatct ttaatttctc ttacaggttc
    68821 ttctagataa aggatatttt taagacgatt ggcaaatttc ttgacttcca tcatttggat
    68881 agcattttca aaatcaatgc gaccagaacg agatgaccca accaaaatca agcccttttc
    68941 taaggcatcg cgagtattga gattgacttt atattcgcta actcccatca tgagaatcgt
    69001 tccctgagga cgaatgtagc gaatcaagtc attaatagct ggtccagtac catcaccacc
    69061 acaacattca aaagcatggt caaaggccaa atcttcagga atattatccg taatatagca
    69121 ttctttggca aatgagaaga gttccaactt ttcccaatga cgaccaataa ccacaatctc
    69181 tgcttctggc aaagtatagt tgataatatt ggcaaccaca aaagctaaac ttccatctcc
    69241 aataacggcg atccgctccc gcttgctatg agcaagagtc aatagacgat tcatagcgtg
    69301 catgcccaca ctgacaaact ctgtaatggc tgcaaccgta tcttcaatag catcataagc
    69361 caccacacga tctttaggga gagaaacaaa ctctctcata aagccatcaa atccactaga
    69421 caagaaatgg gtccctgtca tgtagttttc atagaattct tcatcactct gcataggaga
    69481 ctgattggga atcatgacaa ctttttgacc aacctcgtag gttccggtcg ggtcagaaat
    69541 gacggttcca catgactcgt gaatcattgc cattggaagc tttttattca aaatcttggg
    69601 atcacgtttt ccctgatagt aacgctgatc cgcatgacag acagccatgt agttgggacg
    69661 gataaggata tgattctctt ggtcaatagc ctcttcctga tatttgacat tgataaactt
    69721 aggcttagtt agttgataaa tttgattaat cattttacta gtctttctca atcatacttt
    69781 ttgcaatctt caaatctgtt acggttgtaa tcttcagatt tgagtattca cctttggcca
    69841 aggccacatc ttttcctttg atcacaaaga ttttacatgc atctgtcaag atttccttct
    69901 cttcatcaga aagagatcca taaaggtcca tgaagtcctt gcaacggaat gtttgaggtg
    69961 tttgtccttg ataaaggtga gcacgatttg gaatatctgt aataaattga ccattggtac
    70021 tttcaacgat agtatcaacc gcttctacca ctgtgtccac tgcgtcatga ttttgggcaa
    70081 gttggatatt gtcctgaatc atgcgaagtg taataaatgg acgaacagaa tcgtgggtaa
    70141 caacgatatc ctctggagta agcggacgat aagcatcaat ggcttcaatg attttcttaa
    70201 tacttgtatt gcggtcagca ccaccctttg taatgatgat acgttcctta taaagaggaa
    70261 gatatttatc tacaagatct tctgcatgag aaacccagtc tccatgaaca ccaactacaa
    70321 ttttttcaat acttggctcc aagacaaatt tttcaattgt atgaatcaaa ataggtcgat
    70381 cacctagctc taaaaattgt tttggcaagt tactgatccc catgcgtgtg ccagttccac
    70441 cggcaagaat tcctgcataa atcatctatt ttctcctttg tcttactaaa aaaacttatt
    70501 ctctctatta taccacaatc tagtcctatc ataaaagaaa tactggtcct ccccttctag
    70561 aataggagaa ttatgcagtt ctattattca aagaaactag tccatttcta gtaatgacta
    70621 ggaattctgt agcaattact aataaatggc tgcgaaattt tagagtcctt cagaataata
    70681 tactttcctt aaagaaaact taaaacttaa gatttgaaac ttcaaagtga ttacttgact
    70741 tactgccctt catttcttat tagctaactt tatgatataa tgaaaaacga ggtaaattga
    70801 atgaaaagta taaaattaaa tgctctatct tacatgggaa ttcgtgtctt gaatattatt
    70861 tttcccatcc taactggaac ctatgtcgcg cgtgtcttgg accgaactga ctatggttac
    70921 ttcaactcag tcgacactat tttgtcattt ttcttgccct ttgcaactta tggtgtctat
    70981 aactacggtt taagggctat cagtaatgtc aaggataaca aaaaagatct taacagaacc
    71041 ttttctagtc ttttttattt gtgcatcgct tgtacgattt tgaccactgc tgtctatatc
    71101 ctagcctatc ctctcttctt tactgataat ccaatcgtca aaaaggtcta ccttgttatg
    71161 gggattcaac tcattgccca gattttttca atcgaatggg tcaatgaagc tctggaaaat
    71221 tacagttttc tcttttacaa aactgccttc atccgtatcc tgatgctggt ctctattttc
    71281 ttatttgtta aaaatgaaca cgatattgtt gtctatacac ttgtgatgag tttatcgacg
    71341 ctgattaact acctgattag ttatttttgg attaaaagag acatcaaact tgttaagatt
    71401 cacctaagtg attttaaacc actctttctc cctctgacag ccatgttagt ctttgccaat
    71461 gccaatatgc tcttcacttt tttagatcgc ctcttcctcg ttaaaacagg gattgatgtc
    71521 aacgttagtt actataccat agctcagcga attgtgaccg ttatagctgg ggttgtaaca
    71581 ggtgcaattg gagtgagtgt gcctcgtctc agttactatc tggggaaagg agacaaagaa
    71641 gcctatgttt ctctggttaa tagaggtagt cgaatcttta acttctttat cattccactg
    71701 agttttggac tcatggtttt aggaccaaat gccatcctac tttacggtag tgaaaaatat
    71761 atcggaggcg gcatcttgac ctctctcttc gcttttcgta cgattatcct ggccttagat
    71821 accattcttg gttcccaaat tctctttacc aatggctatg aaaaacgtat cacagtctat
    71881 acagtctttg ctgggctact caatttgggc ttgaatagtc tcctcttttt caaccatatc
    71941 gtggctcccg aatactactt actgacaact atgttatcag agacttctct acttgttttc
    72001 tatatcattt tcatccatag aaaacaactc atccacttgg gacatatctt tagctatact
    72061 gttcgatact ctctcttttc actttccttt gtagcaattt atttcctgat taatttcgtg
    72121 tatcctgtgg atatggtcat taatttgcca tttttgatta atactggttt gattgtcttg
    72181 ttatcagcta tctcttatat tagtctactt gtcttcacaa aagatagcat tttctatgaa
    72241 tttttaaacc atgtcctagc cttaaaaaat aaattcaaaa aatcatagga gtttaaaatg
    72301 aaacaactaa ccattgaaga tgccaaacaa attgaattag aaattttgga ttatattgat
    72361 actctctgta aaaagcacaa tatcaactat attattaact acggtactct gattggggcg
    72421 gttcgacatg agggctttat cccttgggac gacgatattg atctgtccat gcctagagaa
    72481 gactaccaac gatttattaa catttttcaa aaggaaaaaa gcaagtataa gctcctatcc
    72541 ttagaaactg ataagaacta ctttaacaac tttatcaaga taaccgacag tacgactaaa
    72601 attattgata ctcgaaatac aaaaacctat gagtctggta tctttatcga tattttccct
    72661 atagatcgct ttgatgatcc taaggtcatt gatacttgtt ataaactgga aagcttcaaa
    72721 ctgctgtctt tcagtaaaca taaaaatatt gtctataagg atagcctttt aaaagattgg
    72781 atacgaacag ccttttggtt gctccttcga ccggtttctc ctcgttattt tgcaaataaa
    72841 atcgagaaag aaattcaaaa atatagtcgt gaaaatgggc agtatatggc ttttattcct
    72901 tcaaaattta aggaaaagga agtcttccca agtggtacct ttgataaaac aatcgattta
    72961 acctttgaga atttaagcct tcctgcacct gaaaaatttg atactatttt gacacaattt
    73021 tatggagatt atatgaccct accaccagaa gaaaaacgct tctacagtca tgaatttcac
    73081 gcttataaat tggaggatta ggatgcaata tttagaaaaa aaagaaatta aagaaattca
    73141 actagccctg ctggactata ttgatgagac ttgtaagaaa catgatattc cttattttct
    73201 cagttatgga accatgcttg gagccatccg ccacaaaggt atgattcctt gggatgatga
    73261 tattgatatt tccctttatc gtgaggatta tgagcgttta ctgaagatta ttgaagaaga
    73321 aaatcaccct cgctacaagg ttctttccta cgatacatct tcttggtact tccataattt
    73381 cgcatcgatt ttggacactt ctactgttat agaagaccat gttaagtaca agcgtcatga
    73441 taccagcctt ttcatcgatg tcttcccaat tgatcgattt acagacttga gcattgtcga
    73501 caagagctat aagtatgtgg ctcttcgtca actagcttat atcaaaaaat cacgagcagt
    73561 tcacggtgat agcaaactaa aagattttct tagattatgt agctggtacg ctctccgatt
    73621 tgtcaatcct cgctactttt acaagaaaat tgatcaacta gtcaaaaatg ctgtaaccaa
    73681 cactcctcaa tatgaaggag gagttgggat cggtaaggaa gggatgaaag aaatcttccc
    73741 agttgatacc tttaaagaac tgattttaac tgagtttgag ggccgtatgt tgcctgttcc
    73801 caaaaaatat gaccaatttt taacccagat gtatggcgat tatatgacac caccatcaaa
    73861 agaaatgcaa gagtggtata gtcatagcat taaagcttat cgcaaaaact gattgagggg
    73921 gattatacag actactaaga tagaggttat tcaaaaacat aattttagta gaaaatgaaa
    73981 tacatattcc cacaataaaa
//
LOCUS       DAVMCG010000006        68749 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVMCG010000006 DAVMCG010000000
VERSION     DAVMCG010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.006"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..110
                     /locus_tag="VYP66_000470"
     CDS             <1..110
                     /locus_tag="VYP66_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1850075.1"
                     /translation="TVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(602..751)
                     /gene="rpmG"
                     /locus_tag="VYP66_000471"
     CDS             complement(602..751)
                     /gene="rpmG"
                     /locus_tag="VYP66_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1850076.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(767..949)
                     /gene="rpmF"
                     /locus_tag="VYP66_000472"
     CDS             complement(767..949)
                     /gene="rpmF"
                     /locus_tag="VYP66_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1850077.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1101..1301)
                     /locus_tag="VYP66_000473"
     CDS             complement(1101..1301)
                     /locus_tag="VYP66_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1850078.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1304..2311)
                     /locus_tag="VYP66_000474"
     CDS             complement(1304..2311)
                     /locus_tag="VYP66_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1850079.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIVDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2502..4532
                     /locus_tag="VYP66_000475"
     CDS             2502..4532
                     /locus_tag="VYP66_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1850080.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEYYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4536..4820
                     /locus_tag="VYP66_000476"
     CDS             4536..4820
                     /locus_tag="VYP66_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1850081.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4833..6179
                     /locus_tag="VYP66_000477"
     CDS             4833..6179
                     /locus_tag="VYP66_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1850082.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFIGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            6183..7040
                     /locus_tag="VYP66_000478"
     CDS             6183..7040
                     /locus_tag="VYP66_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1850083.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            7037..7969
                     /locus_tag="VYP66_000479"
     CDS             7037..7969
                     /locus_tag="VYP66_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1850084.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFSSRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPEAVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8202..9905
                     /gene="ilvD"
                     /locus_tag="VYP66_000480"
     CDS             8202..9905
                     /gene="ilvD"
                     /locus_tag="VYP66_000480"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1850085.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10111..10191)
                     /locus_tag="VYP66_000481"
                     /pseudo
     CDS             complement(10111..10191)
                     /locus_tag="VYP66_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10249..10590)
                     /locus_tag="VYP66_000482"
     CDS             complement(10249..10590)
                     /locus_tag="VYP66_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1850086.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10714..11565
                     /gene="rgg"
                     /locus_tag="VYP66_000483"
     CDS             10714..11565
                     /gene="rgg"
                     /locus_tag="VYP66_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1850087.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSIDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEKFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11755..13002
                     /locus_tag="VYP66_000484"
     CDS             11755..13002
                     /locus_tag="VYP66_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1850088.1"
                     /translation="MKLLFRNQAYRLLTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTFFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFFGLLFTLSIPVGTACFSLVAIWNMQLT
                     WMLFVGFSLLAIFLTILNLKNDI"
     gene            13080..14369
                     /locus_tag="VYP66_000485"
     CDS             13080..14369
                     /locus_tag="VYP66_000485"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1850089.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPAIDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14624..14938
                     /locus_tag="VYP66_000486"
     CDS             14624..14938
                     /locus_tag="VYP66_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850090.1"
                     /translation="MWVLVFILFIIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKKPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            14948..15154
                     /locus_tag="VYP66_000487"
     CDS             14948..15154
                     /locus_tag="VYP66_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850091.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15154..15351
                     /locus_tag="VYP66_000488"
     CDS             15154..15351
                     /locus_tag="VYP66_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850092.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15354..16088
                     /locus_tag="VYP66_000489"
     CDS             15354..16088
                     /locus_tag="VYP66_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1850093.1"
                     /translation="MKKKRRLLFLMSIVFGGVLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16100..16741
                     /locus_tag="VYP66_000490"
     CDS             16100..16741
                     /locus_tag="VYP66_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1850094.1"
                     /translation="MKLLKNLGWILLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            16759..16989
                     /locus_tag="VYP66_000491"
     CDS             16759..16989
                     /locus_tag="VYP66_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850095.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17031..17108
                     /locus_tag="VYP66_000492"
                     /pseudo
     CDS             17031..17108
                     /locus_tag="VYP66_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            17340..19103
                     /gene="aspS"
                     /locus_tag="VYP66_000493"
     CDS             17340..19103
                     /gene="aspS"
                     /locus_tag="VYP66_000493"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1850096.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETSKTN"
     gene            19081..20022
                     /locus_tag="VYP66_000494"
     CDS             19081..20022
                     /locus_tag="VYP66_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1850097.1"
                     /translation="MKQAKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20142..20222)
                     /locus_tag="VYP66_000495"
                     /pseudo
     CDS             complement(20142..20222)
                     /locus_tag="VYP66_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20358..21344)
                     /locus_tag="VYP66_000496"
     CDS             complement(20358..21344)
                     /locus_tag="VYP66_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1850098.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21354..22154)
                     /locus_tag="VYP66_000497"
     CDS             complement(21354..22154)
                     /locus_tag="VYP66_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1850099.1"
                     /translation="MLPYPFSYFSSILGFRKPLSKRFGLNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYAGTVSQASSVVIG
                     PSQIKELPKNLQLHFDTNELVISKENKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22407..23249)
                     /locus_tag="VYP66_000498"
     CDS             complement(22407..23249)
                     /locus_tag="VYP66_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1850100.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23251..24543)
                     /locus_tag="VYP66_000499"
     CDS             complement(23251..24543)
                     /locus_tag="VYP66_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1850101.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24654..25925)
                     /locus_tag="VYP66_000500"
     CDS             complement(24654..25925)
                     /locus_tag="VYP66_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1850102.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26475..27992
                     /gene="malQ"
                     /locus_tag="VYP66_000501"
     CDS             26475..27992
                     /gene="malQ"
                     /locus_tag="VYP66_000501"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1850103.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28018..30276
                     /gene="glgP"
                     /locus_tag="VYP66_000502"
     CDS             28018..30276
                     /gene="glgP"
                     /locus_tag="VYP66_000502"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1850104.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGENSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31321..31893)
                     /locus_tag="VYP66_000503"
     CDS             complement(31321..31893)
                     /locus_tag="VYP66_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850105.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGIYLAQLWDKNDAIPNNGRINF"
     gene            complement(32514..33362)
                     /locus_tag="VYP66_000504"
     CDS             complement(32514..33362)
                     /locus_tag="VYP66_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1850106.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYNKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33514..33792
                     /locus_tag="VYP66_000505"
     CDS             33514..33792
                     /locus_tag="VYP66_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850107.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            33794..35857
                     /locus_tag="VYP66_000506"
     CDS             33794..35857
                     /locus_tag="VYP66_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1850108.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(35935..37191)
                     /locus_tag="VYP66_000507"
     CDS             complement(35935..37191)
                     /locus_tag="VYP66_000507"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1850109.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADEHNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37333..39798
                     /locus_tag="VYP66_000508"
     CDS             37333..39798
                     /locus_tag="VYP66_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1850110.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALVPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            39863..40774
                     /locus_tag="VYP66_000509"
     CDS             39863..40774
                     /locus_tag="VYP66_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1850111.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41004..41702
                     /gene="dapD"
                     /locus_tag="VYP66_000510"
     CDS             41004..41702
                     /gene="dapD"
                     /locus_tag="VYP66_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1850112.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            41770..42900
                     /locus_tag="VYP66_000511"
     CDS             41770..42900
                     /locus_tag="VYP66_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1850113.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEAGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            42912..43451
                     /locus_tag="VYP66_000512"
     CDS             42912..43451
                     /locus_tag="VYP66_000512"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1850114.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDLQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43435..44112
                     /locus_tag="VYP66_000513"
     CDS             43435..44112
                     /locus_tag="VYP66_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1850115.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIILRYATRNPYIQQLGQSYMTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRLYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44179..45078)
                     /gene="galU"
                     /locus_tag="VYP66_000514"
     CDS             complement(44179..45078)
                     /gene="galU"
                     /locus_tag="VYP66_000514"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1850116.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDEATGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQDEGKDGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFARKFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45100..46116)
                     /locus_tag="VYP66_000515"
     CDS             complement(45100..46116)
                     /locus_tag="VYP66_000515"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1850117.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKPYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVAVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46328..46708
                     /locus_tag="VYP66_000516"
     CDS             46328..46708
                     /locus_tag="VYP66_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1850118.1"
                     /translation="MRKFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(46882..47307)
                     /locus_tag="VYP66_000517"
     CDS             complement(46882..47307)
                     /locus_tag="VYP66_000517"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1850119.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYASSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(47375..48025)
                     /gene="phoU"
                     /locus_tag="VYP66_000518"
     CDS             complement(47375..48025)
                     /gene="phoU"
                     /locus_tag="VYP66_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1850120.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48040..48792)
                     /gene="pstB"
                     /locus_tag="VYP66_000519"
     CDS             complement(48040..48792)
                     /gene="pstB"
                     /locus_tag="VYP66_000519"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1850121.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(48794..49609)
                     /gene="pstA"
                     /locus_tag="VYP66_000520"
     CDS             complement(48794..49609)
                     /gene="pstA"
                     /locus_tag="VYP66_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1850122.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49602..50465)
                     /gene="pstC"
                     /locus_tag="VYP66_000521"
     CDS             complement(49602..50465)
                     /gene="pstC"
                     /locus_tag="VYP66_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1850123.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50583..51458)
                     /locus_tag="VYP66_000522"
     CDS             complement(50583..51458)
                     /locus_tag="VYP66_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1850124.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51625..52956)
                     /locus_tag="VYP66_000523"
     CDS             complement(51625..52956)
                     /locus_tag="VYP66_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1850125.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(52957..53664)
                     /locus_tag="VYP66_000524"
     CDS             complement(52957..53664)
                     /locus_tag="VYP66_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850126.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(53748..54050)
                     /locus_tag="VYP66_000525"
     CDS             complement(53748..54050)
                     /locus_tag="VYP66_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1850127.1"
                     /translation="MTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54037..54258)
                     /locus_tag="VYP66_000526"
     CDS             complement(54037..54258)
                     /locus_tag="VYP66_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1850128.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54220..54777
                     /locus_tag="VYP66_000527"
                     /pseudo
     CDS             54220..54777
                     /locus_tag="VYP66_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55092..56783)
                     /locus_tag="VYP66_000528"
     CDS             complement(55092..56783)
                     /locus_tag="VYP66_000528"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1850129.1"
                     /translation="MNTKELIASELSSIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            56919..57365
                     /gene="argR"
                     /locus_tag="VYP66_000529"
     CDS             56919..57365
                     /gene="argR"
                     /locus_tag="VYP66_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1850130.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57416..59950
                     /gene="mutS"
                     /locus_tag="VYP66_000530"
     CDS             57416..59950
                     /gene="mutS"
                     /locus_tag="VYP66_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1850131.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60097..61791
                     /gene="patA"
                     /locus_tag="VYP66_000531"
     CDS             60097..61791
                     /gene="patA"
                     /locus_tag="VYP66_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1850132.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMIQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKNVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62109..62372)
                     /locus_tag="VYP66_000532"
                     /pseudo
     CDS             complement(62109..62372)
                     /locus_tag="VYP66_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62566..64332
                     /gene="patB"
                     /locus_tag="VYP66_000533"
     CDS             62566..64332
                     /gene="patB"
                     /locus_tag="VYP66_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1850133.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64471..65160
                     /locus_tag="VYP66_000534"
     CDS             64471..65160
                     /locus_tag="VYP66_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1850134.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKHLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65164..65343
                     /locus_tag="VYP66_000535"
     CDS             65164..65343
                     /locus_tag="VYP66_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850135.1"
                     /translation="MEHLVVLFFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65330..66679
                     /locus_tag="VYP66_000536"
     CDS             65330..66679
                     /locus_tag="VYP66_000536"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1850136.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEKIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            66803..68263
                     /locus_tag="VYP66_000537"
     CDS             66803..68263
                     /locus_tag="VYP66_000537"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1850137.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGTIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68277..68711
                     /locus_tag="VYP66_000538"
     CDS             68277..68711
                     /locus_tag="VYP66_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1850138.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNEQ"
BASE COUNT        20203 a        12770 c        14828 g        20948 t
ORIGIN      
        1 ttacagtttc tggtaaatgg tactatacct ataattcagg agatttatta gtaaacacga
       61 ctacacccga tggctatcga gtcaatgcta acggtgagtg ggtaggatag gtatccatta
      121 gctaaatcta atcattctga actaaaaaat cttcttacat atgtaggaag attttttgga
      181 ttctcaaaac tagtttaaaa gactacgcta tttaaaccaa ttttaagaat ggatatataa
      241 ggatattcag aaatctagtt ggtcaacttt tgtattttga atatacctta gatggtgacg
      301 atgtcttggt atatctggta ctcacttaca tattctaact tattttaact aagatacaac
      361 tgtagttggt gaatttgcta caaatagtgt agaggcgtta tttgaaaaat atacaaaaaa
      421 ggaaccccaa cttacatttg agtttctctt acttttaatc gtccgaatcc gtattcttat
      481 ttcaaaaaag gtagtgaaaa aggtagtcat tcgaatgatt tcccttgcaa tatagtgaaa
      541 ttaacaaaaa gaaaaaacgc tgatcaagcg tttttcttct gtattgattc gtattgaatg
      601 cttacttcac ttctgtaaac acaacgtgtt tgcgaagttt tggtgagtat ttcttcaatt
      661 gaaggcggtc tggagtgtta cgtttgtttt tagaagtaag gtacaagcgt tcaccagatt
      721 ctttgtgttc aagtgtaata tttacgcgca tggtatctcc cttctattat tcagctgatg
      781 cagctttagc gattttacgt cctttgtagt atcctttaag tgatacacgg tgagaacgtg
      841 agtaatctcc agtagtttcg tcaaagttta cagatggagc tgttactttg tagtgtgtac
      901 gacgtttgtt tttcttcgct tttgaagtgc gacgtgcagg tactgccatt ttgatttctc
      961 ctttaggtat ttatattcga ttcaatctac tgattttcat caaccatact aggataacac
     1021 attttttttg taaagtaaag ttacttgaca aaaaaagatg aaaaaattct cctgtccgac
     1081 ttgtcagaca ggagaagatg ttaaatatca atctcaaatg gttcgtcaat ggtttctgat
     1141 acgtattttc cgtctttctt ccgttgcttg acacactctg tgaggagata ttcgatttgc
     1201 ccattgactg aacgaaagtc gtcttctgcc catgatgcga gtgcagcgta taactttgtt
     1261 gagagtcgaa gggggatctg ctttttttta gcttcagcca tctttagtaa agacttcctg
     1321 tgttgacaat tggttgtgca tcatgattgc cacaaagaac gacaaggaga tttgaaacca
     1381 tggcagcttt tcgttcttcg tcaagttcta ccaattcccc ttcattgagc cgttctagtg
     1441 ccatttcaac cattcctaca gcaccatcta caatcatctt ccgtgcatca acaatggcag
     1501 atgcttgttg gcgttgaagc ataacggcag caatttctgg agcataagct aggtaagtga
     1561 tacgtgcttc aaggatttcc aagccagcat cctcaacacg actttggatt tcttcacgaa
     1621 tacggttagc aacaatttcg ctagagccac ggagactacc ttcatctgct tgcccgtcac
     1681 ccgtagtatc cacattagga gacacatcgt aaggatagat gcggacaata ttacggaggg
     1741 cgctatcaca ttgcaatgaa agatattctt tgtagttatc aacgttgaag actgccttag
     1801 cggtatcgac aactctccaa gttaccgcga taccgatttc tacagggttt cctaagcaat
     1861 cattgatttt ttgacgagaa ttgctcaagg tcatgacttt gagggaaatg tgtttcttgc
     1921 caatttcaag atttacatca ttgtcatttg atgatttagc tcctaaaaaa ggagattttg
     1981 tgctaacatc accactttgt ccaagtcgag tgtggtttgc agggttgact gctacgctga
     2041 agggattgac aaagtaaaaa ccaggttctt tgatggtacc tgtataatta ccaaagagtg
     2101 tcagaaccag agcttcctga ggtttgacaa cttttaaacc agcatgagct agacctgcaa
     2161 ttacgattag taaaggtccg ataataattc caaaaatgtt ttccgaacca acccccatta
     2221 taaatataaa gataccaagt acgattgtca actcaatgag aatcaatgcg aatacaccat
     2281 ttggttttga attgattagt ttttcagtca taagaatgac ctcccattat ttgatatcta
     2341 aatgatatca ctttgttttt aaaagtcaat agaaagttga aaataatcac taaaaagttt
     2401 cagcccaata atttctttta aaaggtgaga ttatattgtg ctcaaatact cttttattct
     2461 tataattttt acactataat tgtagttaga aaggaagaga aatgtttgat tatagagcac
     2521 tagttatttt gatgactttg atggatcatt gtgagctatc attatatgaa ttatctgtta
     2581 aggtgagctt acctataaag gaagtcaaag aaggaataga ttatttagtg ccttatctag
     2641 ctaataaagg gatagtgctg gataaaaaac aaggtcgcta tagtttatca aatcgtacga
     2701 agcagtcttt gacagatatt attaagtcgg atgaattggt tttaccaaag tcgactcgct
     2761 tagctttaat ctatctttac actttttgcc gattagattt tatatcgaat aatcattacc
     2821 aagacttttt gaaagtaagt aagaatacaa ccttatctga tattcaatca ttaagaaaga
     2881 ttatgttaga taatgatttg gagctagggt acagtagagc aaaaggttat actttacacg
     2941 gttcagagtg gaataagcac cgcttagctt ttcaaatggt tagtgagttg ctggaatcct
     3001 ccatagggat ttggggtttg gattatgttt tatccagttg ggggtattca ttaacttatg
     3061 atttgataaa tcaggtagtt aaagattatt atgagaagct acagctagta cctattgtta
     3121 atcaattaaa agtttacctt ttcggtttag tattcattct gtgtaggtat caaagggatg
     3181 ttgaaagagt atgtctttca gagacattag tatctcctgt tattcaagat ataaccacta
     3241 ttttattgga tacagtggtt gatttgggaa ttatagatac ggtgttttct gaggatgatt
     3301 atcgctatat caccgtttta ttatcaagtt gctttgaagg tgaagtagat gttgctccgg
     3361 tttactttaa tcaattaaca gaggctatta taagtagaat ggaagatatt tctttgttac
     3421 attttaaaca aagggaagga ttgagagaaa atcttcgccg ccaccttata ccggcttact
     3481 atagattaaa gttcggccta cctagttcaa atgaatatgt attgcatgtt aaagaatatt
     3541 atcctgattt atttgaatta gtcaaagatt ctttgatgcc cttgatggac gctattgaca
     3601 atcccatacc tgatagtgaa acagcatatt ttgttatcca tttcggaggt tatttaaaga
     3661 aagcagatac tttgcctcaa aaatggtata aagcagcaat catttgtcct aatggtgtta
     3721 gttcttcatt gatgttaaaa gagaatctat tagcattatt tcctcaaatt gagtttatag
     3781 gaacctcaaa gattgatgat ttacaggtga aagctagtag tgactatgat atggtttttt
     3841 ctaccataaa ggtggagaca gaaaagccaa attatctagt ttcggttatg atgactgaag
     3901 agcaagcaat acaactagta gaactagtgt taaaagattt tccgaattta gagtatgggg
     3961 attttgagat tgaacaaatt ctgaatattg tcaaaagata tggaattatt acacaagaat
     4021 tggaattaag attggcgtta aagaattatc tttaccaaaa aaatgataga aaggaaattg
     4081 taccagtgct agaacaactc attaccaaag aaacctatca ggttagttcg caaaaattag
     4141 gatggaagga ggcgattcgt ttagcagcta aaccgctttt ggatcaagat aagataactg
     4201 agaactaccc tgaggcaatg attcaaaaag tagaagagtt tgggcctttt attaatttag
     4261 ggaagggagt agcaattcct cacgctcggc cagatgaagg tgtgaatgaa ataggaatgt
     4321 caatgttagt tttggaagaa ccgatttatt tattggataa tccagaacaa gaggtaagat
     4381 tgttgatttg tattgcagcc attgataatg agagtcattt aaaggctttg tcacatttaa
     4441 caacaatttt aagagataaa aatcatgttc aaactttaat atcatcaaaa aactatgatg
     4501 acattaaaat gataattaaa caggaggatt agataatgtt aaaaattggt acagcttgtg
     4561 gttcaggatt aggttcaagt tttatggtac agatgaatat tgaatctgta ttgagtgatt
     4621 tgaatgtttc ggatgtagaa gttgaacatt atgatttagg tggagcagat ccaaatgcag
     4681 ctgatatttg gattgttggt cgtgatctag ctgattcagc tagtcatctt ggagatgttc
     4741 gtatcttaaa tagtattatt gatatggatg aactacgaga attaattact aaactttgtg
     4801 aagaaaaagg acttatatag gaggctagcg tcatgatgaa gttcatattg gatattgtta
     4861 gtacaccagc tattttagta gctttaattg caattttagg attagttctt cagaagaaga
     4921 aattacctga tattattaaa ggtggaatta agacctttgt tggtttctta gttgtatctg
     4981 gtggtgcagg aattgtacaa aattctttaa atccatttgg taccatgttt gagcatgctt
     5041 ttcatttatc tggcgttgtg ccgaataatg aagcaattgt agctgtagct ttaacaacat
     5101 atggctcagc tactgcaatg attatgtttg caggaatggt gttcaatatc ttaatcgctc
     5161 gttttactcg atttaaatat atttttttaa cagggcacca cactctatat atggcatgta
     5221 tgattgcggt cattttatca gttgctggct ttactagctt gcctctcatc ttactaggag
     5281 gattagcact cggtattatt atgagtattt ccccagcatt tgtgcaaaaa tatatggttc
     5341 aattaactgg aaatgacaag gtggctttag gtcatttcag ttctttggga tattggttga
     5401 gtggttttac tggtagcctt atcggtgaca aatcaaaatc aacagaggac attaaatttc
     5461 caaagagttt agctttttta cgtgatagta ctgttagtat cactttatct atggcagtta
     5521 tttacattat tgtagctatc tttgcagggt cagaatatat agaaaaagaa atcagtagtg
     5581 gtacaagtgg tctagtttat gctttacaat tagcaggtca atttgcagca ggggtatttg
     5641 ttattttagc aggtgttcgc cttattttgg gcgaaattgt tccagccttt aaaggtattt
     5701 cagagcgtct tgtacctaat tcaaaacctg ctttggattg tccgattgtt tatacttatg
     5761 cacctaatgc agttctaatt ggatttatct ctagttttat tggtggttta gtaagtatgg
     5821 caattatgat tgcttcagga acggttgtta tcttaccagg cgttgtgcct catttcttct
     5881 gtggagcgac tgcaggtgtt attgggaatg catctggtgg tgttcgtgga gccactattg
     5941 gagcattttt acaaggtatt ttaatcagtt ttctcccagt ctttttaatg ccagttttgg
     6001 gaggactcgg tttccaagga tcaactttct cagatgcaga ttttggtcta tcaggaatta
     6061 ttttaggaat gttaaatcaa tttggctcac aagcaggcat tgtgattggt cttgttctta
     6121 ttttagcagt tatgtttgga gtatccttta ttaaaaagcc atctgcaaag gaggaataag
     6181 ggatgatttt aagtaaaaat agagaagatg agttaagaaa atttgcgact aacatccgat
     6241 taaatactct tagaacattg aatcatcttg gattcggaca ttacggagga agtctgtcta
     6301 tcgtagaagt tttagcagtg ctttatggtg aaataatgcc aatgactcca gaaatatttg
     6361 cagcacgaga tagagattat ttcatattat caaaaggtca tggaggacca gctctataca
     6421 gtacactcta tttgaatggt ttctttgaca aagaattcct atattcttta aatacaaatg
     6481 gaaccaaatt accgtctcat cctgatagaa atctaacgcc aggcatagat atgacaacgg
     6541 gctctttagg acaaggaatt agtgttgcaa ctggacttgc atatggtcag agaataagaa
     6601 agagtccctt ttatacttat gctattgttg gagatggtga gttaaatgag ggacaatgtt
     6661 gggaggctat acagtttgct tctcatcaac agttatccaa cttaattgta tttgttgatg
     6721 ataacaaaaa acaattagat ggttttacaa aggatatttg taatccaggt gatttcgtag
     6781 aaaaattttc agcatttgga tttgaatcca ttagggtcaa gggttcagat attagagaaa
     6841 tttatgaagg gattgtccaa ttaaaacagt caaataattc atcacctaag tgcattgtat
     6901 tagatactat taaaggtcaa ggggttcaag agctggaaga aatgaaatcc aatcatcatc
     6961 ttcgccctac tgtagaggag aaacaaatgt taacttcagt tgtagaaaga ttaagtcagg
     7021 aattggagga aacagaatga tgagaagtac gaaagaatta cggcatgtat atagagactt
     7081 ccttttagag gctaatcaaa gtgattctga tatagtagtc ttagaagccg atttgtcaag
     7141 ttcgatggct actcataatc ttgaaaagga ctttggagac cgttatgtga atgttgggat
     7201 tatggaagca gaaatggtcg gccttgcagc aggcttgtct attcaggggt ttagacctta
     7261 tcttcataca tttggtcctt tttcttcacg aagggtattt gatcaattat ttatttctct
     7321 tggatacgca caattggatg ccactgtgat tggatcagat gcaggagtaa ctgcagaaat
     7381 gaatggtggg acacatatgc catttgaaga aattggcttg ttacgtttaa ttcctaaatc
     7441 aatcattttc gaagcaactg atgatatcca atttcgtgaa atattgaatc agacattaga
     7501 cttaaaagga ctaaaatata ttcgaacaat tagaaaagct ccagaggctg tatatcaagg
     7561 tggagaagat ttttctaaag gctacattga gttaagacat ggtgaagatc ttgtaatcgt
     7621 tgcttctggc ataatggttg ctccaagtat tcgagttgca gatgaactgt ctaaattagg
     7681 ttattcagta ggtgtgatag atttatttag aatcaaaccg ataccagaac agataaaaac
     7741 aatgttaagt ggaaaaacta tatttactgt agaaaaccac aatcagatag gtggaattgg
     7801 cagtgcttta tgtgaattat tctctgatga tggaataaca aaaattcatc ggatgggtgt
     7861 tcaagaaaga tttggtcaag tagggaaaat ggattatctt cttaatgagt atggtttgag
     7921 tgaatcgaat ataaaagaga aggttctaga aatttataat gcaagataga tgttaaatac
     7981 acttatttga aagaatttct gtaaaaatta cagtacgtta tttaaagaaa gcggattaaa
     8041 aagcatattc tggtcatcag aaagtgcact aatccgcttt gttgttttta attttaaata
     8101 tttcacatgc gtatagaatt ttctgaaaat tcaagaattt tattctgttc attgccttta
     8161 aattgtgcta taatagtaaa aactgaaatg ggagggataa gatgactgaa ttagataaac
     8221 gtcaccgcag tagcatctat gacagcatgg ttaaatcacc taaccgtgct atgcttcgtg
     8281 cgactggtat gacagataag gactttgaaa catcgattgt gggagtgatt tcgacttggg
     8341 cggaaaatac accatgtaac attcacttgc atgatttcgg gaaactggct aaagaaggtg
     8401 tcaaatctgc aggcgcttgg cctgtacagt ttggaaccat taccgtagcg gacgggatcg
     8461 ctatgggaac gcctggtatg cgtttctctc taacatctcg tgacatcatc gcggactcca
     8521 tcgaggcggc tatgagtggt cacaacgtgg atgccttcgt cgctatcggt ggctgtgaca
     8581 agaacatgcc tggatctatg attgctattg ctaatatgga tatcccagct attttcgcct
     8641 atggtggaac tattgcaccg ggaaatcttg atggtaaaga tatcgacttg gtttctgtct
     8701 ttgaaggtat cggaaaatgg aaccacggtg acatgacagc tgaggacgtg aaacgtcttg
     8761 aatgtaatgc ctgccctggc cctggtggct gtggtggtat gtatactgct aataccatgg
     8821 caactgctat cgaagttcta gggatgagtt tgccagggtc atcctctcac ccagctgaat
     8881 cagctgataa gaaagaagat atcgaagcag caggacgtgc tgttgttaag atgttggaac
     8941 ttggtctcaa accatcagat atcttgactc gtgaagcctt tgaagatgct attactgtaa
     9001 cgatggctct cggtggttct acaaacgcca ctcttcactt gctcgccatt gcccatgccg
     9061 caaatgttga cttgtcactt gaggacttca atacgattca agaacgtgtg cctcacttgg
     9121 ccgacttgaa accatctggt cagtatgtct tccaagacct ctacgaagtc ggtggtgtcc
     9181 ctgcggttat gaagtacttg ttggcaaatg gtttccttca cggagatcgc atcacatgta
     9241 ctggtaagac tgtagctgaa aacttggctg actttgcaga cttgactcca ggccaaaaag
     9301 ttatcatgcc acttgaaaat ccaaaacgtg cggatggtcc gcttatcatc ttgaacggga
     9361 accttgctcc tgacggtgca gttgccaagg tatcaggtgt taaagtgcgt cgtcacgttg
     9421 ggccagctaa ggtctttgac tcagaagaag atgcgattca ggccgttctg acagatgaaa
     9481 tcgttgatgg cgatgtagtc gttgttcgtt ttgttggacc taaaggtggt cctggtatgc
     9541 ctgagatgct gtcactttct tcaatgattg ttggtaaagg tcagggagat aaggtggccc
     9601 tcttgacgga cggacgtttc tctggtggta cttatggtct ggttgttgga catatcgctc
     9661 ctgaagctca ggatggtgga ccaattgcct atctccgtac cggcgatatc gttacggttg
     9721 accaagatac caaagaaatt tccatggccg tatccgaaga agaacttgaa aaacgcaagg
     9781 cagaaacaac cttgccacca ctttacagcc gtggtgtcct cggtaaatat gcccacatcg
     9841 tatcatctgc ttcacgcgga gccgtgacag acttctggaa tatggacaag tcaggtaaaa
     9901 aataaactca tactcgaaaa tctcttcaaa tcacgtcaac gtcgccttgc cgtaggtatg
     9961 gttactgact tcgtcagttc tatccacaac ctcaaaacag tattttgagc tgacttcgtc
    10021 agttctatcc acaacctcaa aacagtattt tgagctgact tcgtcagttc tatccataac
    10081 ttcaaaacag tattttgagc tgacttcgtc agttctatcc ataacttcaa aacagtgttt
    10141 tgagcaacct gcggctagtt ttctagtttg ccctttgatt ttcattgagt atcaaaaagc
    10201 aagccatttt tggcttgctt ttttcatctt taaaagtgat tggcctgctt aacgaggtgg
    10261 taatccaagg gcaatacggc catagcgact gattcgtgtg attttccaag caggcgacca
    10321 ggtaacttca accttgatat ctttgatacc ctcgatttgt ttcagacctg ccacgatttc
    10381 aataggcagg ctttcggcgc aatcacaggc agtatcggtg aaggtcatga caatcttgca
    10441 gagccccgtt tcatccagat tgatttcata aatcagacct agattgtaaa catccaattc
    10501 cacatctgta tcaaaaactt tctctagttt ttcgatgatt tggtcttgca aggccaaagc
    10561 acggtcattg attttgatat cgtctctcat agcagtccct ccacgtgata aatatcctct
    10621 attttctcat aattctgaca atttggcaag tttttgatga attttctgaa aaatatgata
    10681 aaatgaagaa aatacggaat caaggggaag tctatggagc agattggaaa agtctttaga
    10741 caattacgag aatcaagaaa tatctcactg agacaagcaa ccggaggaca attttcgccg
    10801 tctatgttgt cccgttttga aacaggtcag agtgagcttt cggtggaaaa gtttctattt
    10861 gctctggaaa atatatctgc cagtgtggag gagatcctct ttctggcgag aggtttccag
    10921 tatgatacag attctgagtt gagaaaagaa attacagatg tcttggaacc aaagaatata
    10981 gcacctcttg aggacttata tcgcagggag tatcaaaagc atgcccattc tcacaacaaa
    11041 cagaaacata ttctaaatgc cattatgatc aagtcttata tgaagagcat agatgaaagg
    11101 gtagagttaa cagcagagga aggaaaagtc cttcatgatt atttgttttc taccgagatc
    11161 tggggaatct atgaactcaa tttattttca gtcagttctc catttttatc tgtttctctt
    11221 tttactagat atgtacgaga aatggtacgt aaatctgatt ttctaatgga aatgtctggt
    11281 aatcgaaact tttttcatac tatactattg aatggctttt tagctagtat tgagtgtgaa
    11341 aaatttacca atgcctatta ttttaaacgt gttatcgaag agcatttcta caaggaaaat
    11401 gagacctatt tccgaattgt ttatctgtgg gcagaaggtc tccttgatag caagcaaggt
    11461 agagtcaagg aaggccagaa aaagatggag gatgctgtcc gtatttttga gatgcttggc
    11521 tgtaataaat ctgccgaata ctatagaaat acgaccgaat gttgaatatc tgcaaactaa
    11581 gaaaaaattt gaagcgatag aactgttgcc ctttctcagg tcattacaaa agttctatcg
    11641 ttttttgctc attttatttg ttgcatatat tcaaaagaat cgtttcgcaa attcataagt
    11701 gctatactaa agctattctt gatgtagaac ttagaacaag gagggagatt atctatgaaa
    11761 ctattgttta gaaatcaagc ttatcgccta ttgactttgt cacgcttctt caatgctttt
    11821 ggtgcttcga ttttcaacct ggtctttatc gtctatgcat cgaccttgtc acaagcatct
    11881 tttgctgttg ctatggcgaa tattgtcatg attcttccga ccttctttac agtttttgca
    11941 gggattcggg cagattacac gagggacaag gtcaaatgga tggtctatag cggtttgttt
    12001 caggcggttc tattttttct agcagcccta gttgttcagc aagctagtct ctttgccttt
    12061 tctagcctgt gtttgatcaa tgtcattagt gatatcatca gtgattttgc aggtggcctg
    12121 cgtatgcctc ttattaagga aaaagtagct gaagatgatc tgatggaggc ttattctttt
    12181 tcacagttca tcacctatat ttcagctatt ggtggtcaag ctttcggagt ctggctctta
    12241 gctctatcgg tcaacaattt ttccctcgtt gcgggaatta atgcttgctt tttcctcgta
    12301 tcagccacta tcctcttttt aggaaaaagc aaattgagcc tgtcaatgtc atctgctgat
    12361 ggtgaaaact taaaaaatga gaagctttct atcaaagacc agttcctaac aatttaccga
    12421 aatttacgtc tcgtttttct taaaagtgga cagaaaaact ttggttttat gctctttgct
    12481 gtcttgctta ttaattcctt gggtggcgct ttgggtggaa tttataatat cttctttttg
    12541 agccattctc tcttgaattt ttcttataca gaggcactat ttatcaatca attctgtgtt
    12601 ttagtagcaa tcatcatcag tagccttacg ggcaatgatt attttgggaa gcagtccttg
    12661 cctagattga tgatgtgggc gaccgtagga cttagtctag ttggtttggc taatttattc
    12721 aatcaagtcg tgcttggttt gctatttctc ttctttactc tgtatgtgtc tggtaaagtt
    12781 caaccaaaga ttagtgccat gctcatgaaa aatctagctc cagaggttct agctcgtact
    12841 agtaattttt tcggtctatt gtttacctta tccatacctg tgggaacagc ttgtttttca
    12901 ctagtagcca tatggaacat gcagttgact tggatgctat ttgttggttt ttccttgcta
    12961 gctatttttt tgacaattct taatctcaaa aatgatatct aaatcctaat ttttttctca
    13021 ctgttttaat ccctctattt atggtaaaat aagactatta agtttaaaga ggattcccta
    13081 tgaaattaca aaaaccaaaa ggaacgcagg atattttacc tgctgaatct gccaagtggc
    13141 agtacgttga gggctttgcc cgtgaaattt tcaaacgcta caactacgca gaagtgcgta
    13201 cgcctatttt cgagcattac gaggttatca gtcgctctgt cggagataca acggatatcg
    13261 taaccaagga aatgtacgat ttttatgaca agggtgaccg tcatattacc ctccgtccag
    13321 aaggaactgc gcccgttgtc cgttcctatg tggaaaataa actcttcgcc ccagaagtgc
    13381 aaaagccaag caagttctac tatatgggac ctatgttccg ttatgagcgt ccacaggcag
    13441 ggcgcttgcg ccaattccac cagattggtg ttgagtgttt tggctctagc aatccagcta
    13501 tcgatgtgga aacaatcgct atggcagccc attttttgaa ggaaatcggt attcaaggtg
    13561 tcaaattgca cctcaacact cttggaaatc ctgagagccg tgcagcctac cgccaagcct
    13621 tgattgacta tttgacaccg ctcaaggaga ccttgtctaa ggatagccaa cgtcgcttgg
    13681 aggaaaatcc tcttcgtgtc ttggactcta aggaaaaaga agacaaggtg gcagtagaga
    13741 atgcgccgtc tatcttggac tttcttgatg aagaaagcca aactcatttt gatgctgtgc
    13801 gtcagatgtt ggaaaatctt ggagtagatt acatcatcga taccaatatg gtgcgtggtc
    13861 tggactacta caaccacacc attttcgagt ttatcacaga gattgagggc aatgacttga
    13921 cagtctgtgc gggtggtcgc tacgatggtt tggttgctta ctttggaggc cctgaaactg
    13981 ctggatttgg ttttgggctt ggtgtagagc gcctgcttct catccttgaa aaacaaggcg
    14041 tggccctccc tatcgaaaat gccctagatg tctatatcgc agtcttgggt gatggagcaa
    14101 atgtcaaagc cctagaacta gtccaagctc ttcgccaaca aggtttcaaa gcagagcgtg
    14161 attacctcaa ccgtaagctc aaagctcagt tcaagtcagc cgatgtcttt gcggctaaga
    14221 ccctcatcac cctaggagag agcgaagtcg aaagcagaca agtgacagtc aagaacaacc
    14281 aaacccgaga agaagtgcaa gtgtcacttg agacaatcag ccaaaacttc tcagaaatct
    14341 ttgaaaaact aggattttat actcaatgaa aatcaaagag caaactagga agctagccgc
    14401 aggttactca aaacatggtt ttgaggttgt agatgaaact gacgtggttt gaagagattt
    14461 tagaagagta ttaatgatag ataaagtggt caggaactta ctcctgacct ttttcttttg
    14521 caaaatgaca aaaatcataa actttttgac agctatactt gtcaaaaaga aaaagatgtg
    14581 ttacaatgta agcaagttaa gagaaaagaa gaaaggagct atgatgtggg tactagtatt
    14641 tatactattt attattttct tttattctaa taattctaaa aaaatcaaga aactagagaa
    14701 taaaatcaaa aaacttgagc gaaaagagaa aggaaacgca gaaatgtcga gattattgca
    14761 agaaatgatt ggaaagaaac caattataac gggagtgtat attgggccag ataactggga
    14821 agttgtggat gttgatgagg aatgggtaaa gctacgacgt gtagataata cgggaaaaga
    14881 aaaattcaag ttgcaacgta ttgaagatat ccaaaccgtt gaatttgacg gagagtaggt
    14941 gtgtaacgtg caactaaaaa atcgtctaaa agagcttcga gctcgcgatg gtctcaatca
    15001 aactgaccta gccaaactgg caggggtttc cagacagacc attagcctac tagaacggga
    15061 tgagtacacc ccatccatta tcattgccct gaaaatatct caaattttca acgaaacagt
    15121 cgaatcggta tttcgtttgg aggaggacga gtgatgaaca agtataaagt gatttattat
    15181 gtagtggtca tagctttatt agtcagcgta tttctactga ttgggatgga cctaagctgg
    15241 tttaatccct atcaaagcga ccaatttgtt tgggtctact ttgctctcat cccagtaatt
    15301 gaatggattg aaaagaaatc caaaaatcta gcaagtgaaa aaggagaatg aatatgaaaa
    15361 agaaacgtag attgttattt ttgatgtcta ttgtctttgg gggggtcttg ggcatgtttg
    15421 tagggatgtt taaggcacgt gtcgaatccc acgaaattat tttagatgta aaagccttga
    15481 tgccatggat atcagctatt tgtttactga taggtttcat tagtatgttt ttgactttca
    15541 atttcttaaa gaaaagcaga aaatttcatt ccttgtatca agaggaaatg gatgacgatc
    15601 tgaatgaaac ctattatgtg caaatgtatc ggaatcttga gtttggaacc attgctttta
    15661 atattacagg tgtagcgatt ccattggcta tttttatttc attaagtgag gtgattatat
    15721 tgcatacaaa ccctcaaaca tttttccttt ctttcttact ctttgtggta ttcttagtcg
    15781 ctcaaaaatc tctttttaaa accattgcga ttgttcgtca gtttgatttg gaatttttcg
    15841 ctacaccaaa ggatgtcttg aactatataa attcttatga tgaaggggag cgtcaggcta
    15901 atttggaaca gagttttcga attttattcc aattacacca atatgtctta ccagccttat
    15961 atatttttct tattatcatt tctttcttga caggagagat tcagttacta gctttcttgc
    16021 ttgtaggagc catccatgtt tatatcaatg tgatgcagtt acctatggta aaacgttatt
    16081 tcaaataaag gagttatcta tgaaattact taaaaacctt ggctggattc ttctagccct
    16141 tctatccttt ttctttatct atggctttat tcaggggctc gcgactgcgt cgcttgcttt
    16201 aggcgcttca ccctatgctg ttactctact ctatgtggtc ttggctggag tatatgtgta
    16261 cggcatttac aaatggtatc agaaagctcc tgtttatatt gagaagagcg gctttaaccg
    16321 atttatttgg cttcctgcct tggtttggtt cttatctctg gtcgttcaat tcttcttgcc
    16381 agatgatcct tcagtaaatc agcaaatagc gacagacttg accttgtctc aaccactttt
    16441 ctcattcttt gctgtggtta tttttgctcc tttgacggaa gagattgttt ttagagggat
    16501 gttagcacgc tatctctttc ctaagcagga caatagtaaa cgaaccctga tttttcttct
    16561 ggtatctagt cttctatttg ccttgattca ttttccaggt gatgtgcaac aattttttgt
    16621 ctattttagc cttggtttta gtttgggttt ggcttacgtt agcagaaaag gtctggtcta
    16681 cagtatttct cttcacgctt tgaataattt agtcggcttt ttgatgattc tcatgctata
    16741 atagagtcag gaggtcacat gaaacgagta attttattag cagtgattca ggcagtcgtt
    16801 ctatttttca tcattggagc gctagcttat gccttcaaag gcgatttctt ctataactat
    16861 ctagcagttg tctttgctcc tattgcaggt gtactgcgtt ttgggacggc ttacataacg
    16921 gaaattgtct tgcctcgaaa ggcagccgaa atcgctgaaa agcgtaaagc aggcaaaaat
    16981 tcaaaataaa agagtccggt gaagttcatc ggatttttgt attatactca atgaaaatca
    17041 aagagcaaac taggaagcta gccgcaggtt gctcaaaaca ctgttttgag gttgtggata
    17101 gaactgacga agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca
    17161 gtaaccgtac tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatta
    17221 gcgctaattt ttagggcttt cacctgactt ttaaagactg gcaaactttt ctgatgattt
    17281 tcatgaagag cctgcgcttt tatggtaaaa tagtaacaga ataaaagagg agagaaataa
    17341 tgaaacgtag tatgtatgct ggtcgtgttc gtgaggaaca catcggacaa gaaataacct
    17401 tgaaaggatg ggttggccgt cgtcgtgacc ttggtggttt gatctttatc gatcttcgtg
    17461 accgtgaagg aatcatgcag ttggttatca accctgaaaa agtatctgca gaggttatgg
    17521 caacagctga aagccttcgt agcgaatttg ttattgaggt gactggtcag gtcgctgcgc
    17581 gtgagcaagc caatgataag ttgccaactg gtgcggttga gttaaacgtg acagctctta
    17641 ttgtgcttaa cacagctaag acaacaccat ttgagattaa ggatggcatt gaggcaaatg
    17701 acgatacacg tttgcgttac cgttaccttg accttcgtcg tccagaaatg ttggaaaatc
    17761 ttaaacttcg tgccaaggtg acccactcta tccgcaacta tttggatgag ttggagttta
    17821 tcgacgtgga gacaccattc ctttctaagt caacgcctga aggggcgcgt gattatttag
    17881 taccgtctcg tgttaataag gggcattttt acgctcttcc tcaaagtcca caaatcacga
    17941 aacagctctt gatgaatgct ggttttgacc gttactacca aatcgttaaa tgtttccgtg
    18001 acgaggactt gcgtggagac cgccagcctg aatttactca ggtcgacttg gaaacgtcct
    18061 tccttactga gcaagaaatc caagatatta cagaaggctt gatcgcgcgc gtgatgaagg
    18121 aaacaaaagg catcgaagta acgctaccgt tccctcgtat gaaatacgat gatgctatgg
    18181 ctctttacgg ttctgacaag ccagatactc gttttgacat gttgcttcag gacttgacag
    18241 aagtggtcaa aggtgtagac tttaaagtct tttcagaagc acctgctgta aaagcgattg
    18301 tggtcaaagg agctgcggac aactattcac gtaaagacat cgacaagatg acggaagtag
    18361 ccaaacagta tggtgccaaa ggtcttgctt gggtcaaggt ggttgatgga gaattaaacg
    18421 gaccagttgc caagttcttg actggtatcc aagaagaatt gacaacagcg cttgctcttg
    18481 aagataagga cttggttctc tttgtggcgg atacgcttga agtggctaat gcaacactgg
    18541 gtgcccttcg tggacgtatt gctaaagagc ttggcttgat tgataatgat aagttcaact
    18601 tcctttgggt ggttgactgg ccgatgtttg aatggtctga agaagaaggc cgctacatga
    18661 gcgcccacca tcctttcacc cttccacagg aagagactgc tcacgaatta gaaggtgatt
    18721 tggctaaggt tcgtgccatt gcttacgata tcgtcttgaa cggttatgag cttggtggtg
    18781 gtagccttcg tatcaaccaa aaagaccttc aagaacgcat gttcaaggct cttggtttct
    18841 caactgaaga agccaatgac cagtttggtt tccttcttga agccatggac tatggtttcc
    18901 caccacacgg tggtttggct atcgggcttg accgttttgt catgttgctt gctggagaag
    18961 aaaatatccg tgaagtcatt gcctttccta agaacaacaa ggcaactgac ccaatgacac
    19021 aagctccatc aacagtcgct ctcaaacaac tagaggaact cagcttacaa gtagaagaag
    19081 atgaaacaag caaaacgaat taagcgatgg cgctattatc tgcgccgctt tgcttatcag
    19141 ataaaaattt tacgtgtctt acaaagtatc tctcgagaaa agtatgatga gaagatttcg
    19201 gcctctctgg tctatggttt tttatcagca gtagcagtta atttcttttt ccaaccaggg
    19261 catgtgtatt cgagtggtgc aacaggtctg gcacagatta tctctgcctt gagtaatcac
    19321 tggtttggtt ttcatattcc gatttcgcta agcttctacg ccattaactt ccctttgatg
    19381 gtcttagctt ggtatcagat tggccataag ttcaccgtct ttacctttat cacggtatct
    19441 atgagttcct tctttatcca gtttgtccct gtggcaacct tgacggagga tcccattatc
    19501 aattcccttt ttgggggtgt tgttatgggt ttggggattg gttttgctct tcgaaacaat
    19561 atctccagtg gtgggacgga tatcgtcagc ctgactattc gcaagaaaac gggtaagaat
    19621 gtcggtagta tttctttctt ggtaaatgga actatcatgc tgatagcagg tttaaccttt
    19681 ggttggaaat acgctcttta ttctatgatt accatctttg tctctagccg tgtgacagac
    19741 gcagtcttta ctaagcaaaa gcgtatgcag gccatgattg tgacaaatca tccagagaag
    19801 gtaattgaaa aaatccataa aaaattgcac cgcggagcaa ccatgatcca cgatgcagaa
    19861 ggaacctata atcacgagag aaaggcagtt ttaatcactg tcattacacg tgcagagttt
    19921 aatgaattta aacagattat gacacaagtg gatccaagct cctttgtctc tgtctcggaa
    19981 aatgttcata ttctaggaag atttgttgag atagataatt agtgattaat actcttcgaa
    20041 aatctcttca aaccacgtca gcttcacctt gccgtatata tgttactgac ttcgtcagtt
    20101 ctatctgcaa cctcaaaacc atgttttgag ctgacttcgt cagtttcatc tacaacctca
    20161 aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gcactttgat tttcattgag
    20221 tataaaaaga tcttgggaaa agactcaatt tcagtagaaa aggaagtaaa tcttcccaca
    20281 ataaaacgca tagtatcaag ttttttcaat acctgatagt atgcgttttt gcttttaacg
    20341 actttttgcc cagtctctta tttttcgata attttgtggg cgatcaattg acggtaacaa
    20401 atttgtttat tgtttttatt atcattaata atctggagaa tagtttcaag ggaaacacga
    20461 ccaagctcta aactattgat atcgacatag gctgccaagt tgagcttggg attaaccgag
    20521 tcaaagctga gaacagggac atccagctgg tgtttggcaa tatagttaca aacaccttca
    20581 gctaggaggc tatcggttgt gatgatagca tcaatttgtg gatcgtgctt gaataatcgc
    20641 ttgctaaatt tatagccctt ttcttccaga aactcgtcgg caaagtagat gcgattgttg
    20701 tcagtggtaa gtttgtaatg tttaagcgcc tgttcatagc ctgttaaacg gtctttggtc
    20761 acgaagagct ttttacttcc tccgataaag gcaatgcgtt tgcagccttt tttgatgaaa
    20821 tattcagtcg catcaaaacc agcttgaaca ttgtcgttgt cgacaagtgg gatgaaagga
    20881 gatagagatt tacctaagat aaggaagggg aactgttctt ctgcgacgag ttttacgaga
    20941 gggtcttctt cttgggcata gagaaagatt agcccatcta cacgcttgcc gtagaccatt
    21001 tgtgaaatag cgttgagacg ctccttctca tctttccctg ttgctatctg aatggcatag
    21061 tggttttcag atgcgacttg agagatgcca cgtagaaccg atggaaagaa aggattctgg
    21121 tagaaggcgt ctgagtcatc aggaagaact aatccgataa cctgagtata gctgcttacc
    21181 aagctacgag cgttgaggtt tgggtggtag ttgagttcct tcatagcttt gcgaacgcgt
    21241 ttttttgttt cgtcgctaat ggttgattta ttttgaataa cacgggttac ggttgaaggc
    21301 gaaacaccag cagccttggc cacgtcttta atcgtaacgg gcataaaaat ctcctattta
    21361 tggtaatttg gatcacggaa atgtgtttta taaaagatag tgaccagata cagaacaaaa
    21421 agaatatttt gtacagtaat cagggttgtc atattttggc caaataatcc caaaataagt
    21481 gtaatcagag tcggcaatcc taaacagttc aagataaagt gatagcactc tttaaaggtt
    21541 ctaaatgaaa agaggcgtga tttcttagtg atataaagga gaagactagc tcctagagag
    21601 acgataaaga aattcaaacc aaagaggaag ctcgcaccga gaactaggaa gaggctgata
    21661 tagacacgat tttgttggta ccagtcttta gaaattgctt gggtcaagct gtctttgctt
    21721 ttgaaactct cagtctgaat ggctcggtaa gagatgcggg tcagttcctt gttttccttg
    21781 ctgatgacta gctcatttgt atcgaaatgc agttgcaagt tcttaggtaa ttccttgatt
    21841 tgacttggac caatcacaac agaagaggct tgactaactg ttccagcata agttaatgtg
    21901 ccatcgacaa ttgtagcatg ttcagagaga tcctggacaa cctcatttgt cagaggttca
    21961 tagacattat cgataaaagt ttctagcgga taggtctcct gggagctgtt ttggatagca
    22021 atgggtacca tagacaagct gataaggaag atactggtaa agagaagttg aaaccagttg
    22081 agcccgaaac gtttggacag gggcttacga aaccccaaaa tacttgaaaa ataggaaaat
    22141 ggatatggaa gcataggtat ctttctaaaa ggtgttttct atatgagtat tattatatag
    22201 agaaatgcgc tttatttcaa gtctaggaga aaaattgctt gctacaagga tattatttac
    22261 agtgacaatt gctaataatc aatgaaaatc aaagtgcaaa ctagccacag gttgctcaaa
    22321 gcacaacttt gaggttggag ataaagctga cgtggtttga agagattttc gaagagtata
    22381 aaatgaaaaa gggtggcggg gataaattat cccttgtcgc caccacttgt aagtcctgaa
    22441 acaaagttct tttgtaggaa gaagaagaga atacagattg gaagggcgat gaggatagca
    22501 cctgctgaga agtaggcaat cttcaagttt ttcgcattgt taacgaaggt ttggagacct
    22561 acggcaacag taaagtattc tttctcacga agcaagaaac tagagaggat gtagtccccg
    22621 aaaggtccca tgaaggccca gagagcttgt acggcaacca ttgggcgaac aagtggtaga
    22681 acaatttgcc agaagcggcg gaagtgtcct gcaccgtcta gttttgcaga ttcgtctaaa
    22741 gacattggca ctgtatcgaa gtagcctttc atgagccaag cattcatcgg gataccacca
    22801 ccaacgtaga ggaagatgag gaaccagttg tggttaaggg cgttcaacat aagcgccata
    22861 acgaagaagg ctgtcaaagc ggccatagtt ggcaccattt ggatgatcaa gaagaagacc
    22921 aaactttgtt tacgagccaa gaagttgtaa cggctgtaag cataaccagc aagtacgatg
    22981 atacttgttt gaacagccat ggtaattaag gcgataatca aagtgttgag gtaccaagta
    23041 ccgtacaagg tttcagtgaa gaggccttta aagttatcaa aattgaggtc gatattagta
    23101 tctagtttaa aggctgagac gttacctgct ttaaaggctg acataatggt aatcaacagt
    23161 ggatagataa ttacaattga tagaccaatc aggtaaaggt aagtaaggct ttgagtcagt
    23221 ctacgtttga gtttaattga gttattcatc ttagacgtcc tccatatcaa atgcgtgtag
    23281 tttcttgaat gcgatcatag agattgagat gacaatgata gagataatca aggtaacagc
    23341 tgccgccatt gagtattgag gagatgtacc tgttgtcaaa cggtagatcc atgagatcaa
    23401 gatatcggtt gaaccagctc cacctccgac actaccaggt cctccaccat tgaagaggta
    23461 catgatagag aagttgttaa agttgaaggt gtattggcta atcaaagtag gtgccgcaac
    23521 agccaaaatc attgggaaag tgatgttgcg gaatttttgc caagcgttgg caccgtcaat
    23581 ataagctgct tcgtaaaggt cgttaggaat agattgcaag atacccaaag tcaaaacgta
    23641 gatgtatggg aatccgagcc aaccttgcat cataatcaag gcaatcttag tccaagttgg
    23701 gtctgttttc caaggaataa gagctccatc aaggaaagga aggaatttag ccaagattgg
    23761 caatacttga gtgttgatag caccgacact atcgttaaac atgtttgaga atgtcaagat
    23821 agtgatgaag gctgggacag cccaaggaag aaggaaaata acaccaaaga tacgttttcc
    23881 tttgataaat ggttggttgg caatgatagc tgtgaagata ccaattacga tttgtaaagt
    23941 agaagctgcc aaagcccaaa tgatagtcca agaaagaaca gaaccaaagg cagaacggaa
    24001 ggtactcaag ctccaaatgt ttgtaaagtt ggtcaaacca acccagtcca acaacttgtt
    24061 tggtggcaag tgttggaagt cgtagttggt aaaggcgatc atcaaggtta cgataactgg
    24121 gaagataatc gcgaaggtca tggcaacata agatggaatg atcaagaggt aagggaagcc
    24181 attttcataa atccctttga tcatgtcttt gagtgtgcgt ggaactggaa ttccattgtt
    24241 aatgcgtttt gcaatcgtat gtgcatcttt gatatttgag aaataaaaga gtacataaac
    24301 gattacaaag attagatgga aggcaccacg aatcagcata aagagggaat tatcacgacc
    24361 tggtttgtca ccaagagtga tgaggttgct caattcaggg gttgcaagtg ctaggaagta
    24421 aaggacaaat acgatggtta caccaaggaa gataaaacct ttggcttttt gtttattgta
    24481 aatctgtcct aacccaggaa tgatagacag cagggctgct ttactaggtt gttgcttttc
    24541 catattaact cctttcatag gatactactt ttttataaga aagctaaatt atttgtgtct
    24601 ctattgataa attcaaaggg ggatttgatt tccacccccc ttgaacaaat tttttattca
    24661 ccaaattttt gtttgattgt ttctttgatc aatgttacag catcgttagc agctgtttta
    24721 gcatcttttt gaccacttac agcatcaaag agcatatttt tcgctggatc ccaaactgca
    24781 gacatttgag agatgtttgg cagtggttga gtgttcttga actgtttgat aacagctgtt
    24841 gtcaactcat cgtttttacc ttcagcgtat gaacgagcct cagtattagc tgggatttcg
    24901 ttagtcttat catataatac tttttgttgt tcagttgcaa caaggaagtc tacaaatttt
    24961 tgagaagctt caaggttctt aacggcttga ggaatgaccc aagctttacc accaccgaat
    25021 gcagcatatt cttttccatt tggaagagtt gggatagttg caactccgta gtttacttta
    25081 gcatctttaa aggcttgagc tttccaaggt ccgtcgatga tagcagctgt tttaccttct
    25141 tggaattgag tttggattaa gtttccagca ccttctgtat cttgcatacc tttaggccat
    25201 ttttcgtacc aagatttagc gtagttgata cctgcgatag aaccgtcgtt tgcaagaccg
    25261 atgtctttag cgtctttacc gttttggcca aagacgtaag caccgttacc ggcaagaagt
    25321 ccatatgtat agtagaagtt tgtccagtca gctaggaagg cagtagtttt accatcttca
    25381 ccagcgaatg cgtatttgct atctttagca aggttttcca agtcagcaaa tgtttttgga
    25441 gcatctttca ccaagtcttt gttgtagtac ataacaagtg actcgataac ggcaggagca
    25501 ccgtaaactt taccattagc agctgttaca agagatttag ttgtgtcgtc tgttttagca
    25561 ccatcgctca atttcacttc tgaaagttgt ccgtcagaac caaggctacc tacacggtcg
    25621 tatggagcca tcataacatc agggacatta ccagattggt tgtcaagaga aagtttatca
    25681 agacctccta gagcatcacc agttttaaga gtgactttta ctccagcttc tttttcataa
    25741 gctttagcaa cctcttcaat atagctctta tatccctcgt ctacatatac agtgagttct
    25801 ttgacttcag atgaaccaga atcagcaggc ttatcagcag ttttgcttcc gcaagctacc
    25861 aaaagcaagc tagcaagtgt aacagttcca agcaccgcag tgctcttcat aaatttagat
    25921 gacatagtgt attcctccca aagaatagca agttttattg ataaggaaac gcaaacgttt
    25981 tcctttatga gcttagtata gcacaaatag aaaacggttg caagtatttt ttgtaaaaat
    26041 tttaaaaaat ttttaagctt gatttgatag cataattttg cattttaata gaagaaaagt
    26101 atgaaataga taagaataca gtatttttaa taaaaatata tggaatctgt ctaaagaggg
    26161 aaaccaggag gggctacctc cctggttcta atccctatct attttctatg gacgtttgtg
    26221 ctttgttaca tataaattca agctccctaa ggaggttttg tactttgtag actgtctcgt
    26281 gagagtcaaa ccttaggatt agatagtttt aagttatctt tgctaaaatg agttagtctc
    26341 cttaaaaata atcaaaaaag ttttttaaaa acgcttgcaa ttatgcttga aaaggagtat
    26401 acttataagt aacgcaaacg tttgcgtctg caaaatacgc aacgttccat tattttaaca
    26461 cacgaggtgc tattatgaaa aaacgtcaaa gtggtgtgtt gatgcacatc tcttctcttc
    26521 caggagctta cggaatcgga tcatttggtc aaagtgctta cgacttcgtt gatttcttgg
    26581 tccgtacaaa acaacgttac tggcaaatcc ttccattagg agcaactagt tacggggatt
    26641 ctccttacca atctttctca gccttcgcag gaaacactca ttttatcgat ttagatatct
    26701 tggtggagca aggtttgttg gaagcaagtg accttgaagg agttgacttt ggtagcgatg
    26761 cgtctgaagt tgactatgct aaaatctact atgcacgtcg tcctctttta gaaaaagcgg
    26821 tgaaacgttt ctttgaagtc ggagatgtta aagattttga gaaatttgct caagacaacc
    26881 aatcatggct tgagctcttt gctgagtata tggctatcaa agagtatttt gacaatcttg
    26941 cttggactga atggccagat gcagatgctc gtgctcgtaa agcttcagca cttgaaagct
    27001 atcgtgagca attggcagac aagttggttt accaccgtgt gactcaatac ttcttcttcc
    27061 aacaatggtt gaaattgaaa gcttacgcta acgacaacca catcgaaatc gttggggaca
    27121 tgccaatcta cgtagcggaa gattcaagtg atatgtgggc aaatccacat ctcttcaaaa
    27181 cagatgtcaa tggtaaggct acttgtatcg caggatgccc accagatgag ttttctgtaa
    27241 ctggtcagct ttggggtaac ccaatctatg actgggaagc aatggacaaa gacggctaca
    27301 aatggtggat tgaacgcttg cgtgaaagct tcaaaatcta cgatatcgtt cgtatcgacc
    27361 acttccgtgg cttcgaatct tactgggaaa tccctgctgg ttccgataca gcagcacctg
    27421 gtgagtgggt gaaaggtcca ggctacaagc tttttgcagc cgttaaggaa gaacttggtg
    27481 agctaaacat catcgcagaa gaccttggct tcatgacaga tgaagtgatc gaattgcgtg
    27541 aacgtactgg cttcccagga atgaagattc ttcaatttgc cttcaaccca gaagacgaaa
    27601 gcattgatag cccacacttg gcacctgcta actcagttat gtacacagga acacacgata
    27661 acaatacggt tcttggttgg taccgtaatg agattgatga tgcgactcgt gagtacatgg
    27721 ctcgttacac gaaccgtaaa gaatacgaaa cagtggtaca cgctatgctt cgtacagtat
    27781 tttcatcagt tagctttatg gcaattgcaa ctatgcaaga tttactagaa ttggatgagg
    27841 cagctcgtat gaacttccca tctacccttg gtggaaactg gtcttggcgt atgactgaag
    27901 atcaattgac accagctgtc gaggaaggtt tgcttgactt gacaacaatt tatcgccgaa
    27961 ttaatgaaaa tttggtagat ttaaagaaat aagacaataa tcaggagaca actaaacatg
    28021 ttatcactac aagaatttgt acaaaatcgt tacaataaaa ccattgcaga atgtagcaat
    28081 gaagagcttt accttgctct tcttaactac agcaagcttg caagcagcca aaaaccagtc
    28141 aacactggta agaaaaaagt ttactacatc tcagctgagt tcttgattgg taaactcttg
    28201 tcaaacaact tgattaacct tggtctttac gacgatgtta aaaaagaact tgcagctgca
    28261 ggtaaagact tgatcgaagt tgaagaagtt gaattggaac catctcttgg taatggtggt
    28321 ttgggacgtt tggctgcctg ctttatcgac tcaattgcta ctcttggttt gaatggtgac
    28381 ggtgttggtc ttaactacca ctttggtctt ttccaacaag ttcttaaaaa caaccaacaa
    28441 gaaacaattc caaatgcatg gttgacagag caaaactggt tggttcgctc aagccgtagc
    28501 taccaagtac catttgcaga ctttactttg acatcaactc tttacgatat tgatgttact
    28561 ggttatgaaa cagcgactaa aaaccgcttg cgtttgtttg acttggattc agttgattct
    28621 tctattatta aagatggtat caactttgac aagacagata tcgctcgcaa cttaactctc
    28681 ttcctttacc cagatgatag tgaccgtcaa ggtgaattgc tccgtatctt ccaacaatac
    28741 ttcatggttt caaacggtgc gcaattgatc atcgacgaag caatcgaaaa aggaagcaac
    28801 ttgcatgacc ttgctgacta cgcagttgtc caaatcaacg atactcaccc atcaatggtg
    28861 attcctgaat tgattcgtct tttgactgca cgtggtatcg atcttgacga agcaatctca
    28921 attgttcgta gcatgactgc ctacactaac cacacaatcc ttgctgaagc gcttgaaaaa
    28981 tggcctcttg aattcttgca agaagtggtt cctcacttgg taccaatcat cgaagaattg
    29041 gaccgtcgtg tgaaggcaga gtacaaagat ccagctgttc aaatcatcga tgagagcgga
    29101 cgtgttcaca tggctcacat ggatatccac tacggataca gtgttaacgg ggttgcagca
    29161 ctccatactg aaatcttgaa aaattctgag ttgaaagcct tctacgacct ttacccagaa
    29221 aagttcaaca acaaaacaaa cggtatcact ttccgtcgtt ggcttatgca tgctaaccca
    29281 agattgtctc actacttgga tgagattctt ggagatggtt ggcaccatga agcagatgag
    29341 cttgaaaaac tgttgtctta tgaagacaaa gcagctgtca aagaaaaatt ggaaagcatc
    29401 aaggctcaca acaaacgtaa attggctcgt cacttgaaag aacaccaagg tgtggaaatc
    29461 aatccaaatt ctatctttga tatccaaatc aaacgtcttc acgagtacaa acgccaacaa
    29521 atgaacgctt tgtacgtgat ccacaaatac cttgacatca aagctggtaa catccctgct
    29581 cgtccaatca caatcttctt tggtggtaaa gcagctccag cctacacaat cgctcaagac
    29641 attatccatt taatcctttg catgtcagaa gttattgcta acgatccagc agtagctcca
    29701 cacttgcaag tagttatggt tgaaaactac aacgttactg cagcaagttt ccttatccca
    29761 gcatgtgata tctcagaaca aatctcactt gcttctaaag aagcttcagg tactggtaac
    29821 atgaaattca tgttgaacgg agctttgaca cttggtacta tggacggtgc taacgtggaa
    29881 atcgctgagt tggttggaga agaaaacatc tacatcttcg gtgaaaattc agaaactgtt
    29941 atcgaccttt acgcaaaagc agcttacaaa tcaagcgaat tctacgctcg tgaagctatc
    30001 aaaccattgg ttgacttcat cgttagtgat gcagttcttg cagctggaaa caaagagcgc
    30061 ttggaacgtc tttacaatga attgatcaac aaagactggt tcatgactct tcttgatttg
    30121 gaagactaca tcaaagtcaa agagcaaatg cttgctgact acgaagaccg tgacgcatgg
    30181 ttggataaag tcatcgttaa catttctaaa gcaggattct tctcatctga ccgtacaatc
    30241 gctcagtata acgaagacat ctggcacttg aactaatact cttcgaaaat ctcttcaaac
    30301 cacgtcagct ttatctgcaa cctcaaagcg gtgctttgag caacctgcgg ctagcttcct
    30361 agtttgctct ttgattttca ttgagtataa gatacaaatt tatactaata catcttgtaa
    30421 aaaagcgagt ttcaattgaa attcgctttt ttaaatgctg tggatttggg tcaatcttgt
    30481 ctaaaaatag ggaaatccta gatacagtga aggctttaaa tgctggtttt tactgtcttc
    30541 agccttatat tttttcgtag ttggttacct cacatctatt atattcgctt acataaagta
    30601 ttataatata attgtaggaa agaaggtgtt tttatgatat acacacttaa attggtgttg
    30661 tttattacct ttcttgtaat aagcttgtta cctgataaga tttttggaaa aaataaaaaa
    30721 atttggaaaa tagtttttgc aatattgacg gcagtggcag cattgtcatt tatgtactaa
    30781 gttattttaa gaatgtaggg aaataaaccc tacatttttt ttagtttttt ctgttttcta
    30841 aattctattt atccaagagc ttcaacattt cttgcttctt cgcttcaagt tctgcacgct
    30901 tttcttcgat ttcggcatgt tttttctcga gttcagaaca acttgcatca ttgctaaatt
    30961 cttttcgcca tcaggagata gggtgagtct acatgtctat tactcaccca aagcagtcct
    31021 acaaagcagg aattttctgt tacttttttg gaaatagtaa cgtttataca gctttgacac
    31081 ttcgtatcaa agcgccaaac acactccgag ggatttacag aaagcagaaa aggaatgatc
    31141 tggtataaga tcattccttt tctctctttt tctttaagta attatataca atgtacgacg
    31201 aagtcgtcat tgcaatgctg atccaccacc taaagggaac tttaaacaac attgataaga
    31261 taaagaatat aaacaacgaa aatacgttat acccaattaa ttttattgta tatctcatga
    31321 ttaaaagtta atccttccgt tgttaggaat ggcatcattt ttatcccata attgtgctaa
    31381 ataaatcccc ggtgataata aattcatagc gaattctaaa gcaacatcat ttacaaacca
    31441 actacctaga tatctagaaa ttgctgaacg aatagcactt tttgctgcat gttttccttt
    31501 tactttaatt agatttgcaa ggcctgcagt agttcctcct aatgctaaag ctattgcagt
    31561 atctaataga gcacccattt gattaactgt aataccttgc caagctgctc taaatggaga
    31621 gtatgtaggt gggattgtat aatcgccttg taattgtcgg ttaattactt ctttgatcca
    31681 ttgttgtgag acgtctggat gaaaagattg gatttcgttt gcaagtgtat tgatttgttc
    31741 ttctgttaga gaagtgacag gttgaagttc catatttgtt tcaatttgtg atacttgttc
    31801 agaagcgtat acagctgaaa cacttggaat cgctgataca attaacacaa ttgacgtcaa
    31861 aaaaaccgaa ataaatttca ttaatttgtt catgagcttt tctccttttt atttgtatct
    31921 gcttacattt tatcatatac tgttattata gtcaaaaaaa tatgctatta tgttaaaaaa
    31981 tatttttcaa aatataaatg gacggattta ttttggattt tatttgttat tttgacctgc
    32041 ctctatattg gtaaccatga tttgtttact ctcaatcatc aagaattctc ttttcgtggt
    32101 agcgtttggg gtctggtact ggccttatat cacttattgt tcattgataa gtttgtaatt
    32161 tcgaatcgaa aataaagatt agaactatga ttgactggct acttttaata ttgattttgg
    32221 aggaagattt tgtctctatt atttattatt ttaaatttat ctattttgta caagatttat
    32281 tctttgagac gggagaaatc gaaatacttg atttatacgg cctatatcat atttggggta
    32341 aatgtagtat atggtattca atggttatta agagaactga tttcaactat ttccccttaa
    32401 tgtgtatgga aactataaca aaacgcataa gattaaggtt tgtgtacctg ttcttatgcg
    32461 tttttataat attgaagatt ttcggtaagt tttatacctt tgggaagtct agtttagaat
    32521 gctttcccaa ccaaaatctc tgcttcgatg gtaatctctg tcagttggct ccagtcaatc
    32581 ttgctctggt caacgtgaaa gaggagagga gtcatactga gtagggcttg gagttgttct
    32641 gctgtgatag tcttagtcag agaggcagtt tgactagata ggatggtaaa gtgttcctgg
    32701 aaatgctcct tgatatcttg gttagaatac tccttgtttg tcagctggtc ctgtactctt
    32761 tgacggattt ctttgaggtg attttcagtt gggataacct ttatcaagat accgtctttg
    32821 gataaaacgc gacgaaattc tccatagttg gcaggtgaga agatatcaag cagaatatcc
    32881 atgttagcgt cttttatagg aagtcgtgcc aagtcgccaa caaaccaatt gactgcccag
    32941 ttgggttcac ttttagcagc gatttggact gaatctttgg agatgtcaaa ggcatagaaa
    33001 gttttttcag agtgactttc ttgtagtttg cgagaataga atccttcacc acaaccgata
    33061 tccaaaattg ttgtggtagt ttttgagctt gcaagcaagt cagatacagc atctaagata
    33121 gcttggtaaa agccggcttc taggatttgt tgacggtttt gaaaattttc cttgttatag
    33181 ttagcagatt gcttgatttg aggtgctaga ttgacatagc caaatttcgc caagtcaaaa
    33241 gaatgacggt tgcagcactt gaaattagtc tctaacagag tcagattttc ttgacagata
    33301 ggacaggcaa aggcagtcgc agaagcaaaa cgctgaagtt tgggcttgag atttgtattc
    33361 atagtttaag tgtatcaaaa gaggcaaatg aaagcaactt taggaataag tagatgggag
    33421 attcagtaga aataaaacta attctccaat ttatagaatg aaattgcttt tatatctaaa
    33481 ttgctatata ataatgataa ggaggaaata agtatgttaa aagaagtatt aaccgttgca
    33541 aaagttgcga aaaaatcttc attatttttg ggtggtgtcg catttggtac ccttggtttg
    33601 aaaatcttag caagtaagga agctaaaaaa ggttattcta aagctttggc taaggcttac
    33661 aagttgaaag acgagctaga tgcatctgtt tctgttgtga agcaacatgg agacgatgtc
    33721 ttgcaagatg ccaaatattt gtacgagcaa gagaaaaaag aagagcaatt agatagcctt
    33781 ataggtgaat aatatgtctt ttaaagtgct acatagagga taccaacata tccgactatc
    33841 atcttctttt tcacttacct tggatattca agactatctt cgttccttgg cgagagatga
    33901 aaaggggatt gagtctatcc agttttacat ggatcaacag cactttactc tacgcataaa
    33961 agaaggcttt tctgtattag ataatgcaga agccttttta aaaagaattg ataaagggaa
    34021 agtttctgag ttgatgactc ttcccattcg tagagaagag agtgcttatt ctattgtttc
    34081 aggtgcagcg gttaagcgtg tactttttcg tagttttgtg ccgtatccta ttcgctatat
    34141 atggacttgt tatcaggctt tgggttatat tagagaagcc tatcaaacac tagcgcgtaa
    34201 ggaactaact atggaagtct tggactgttc ggctatttta ttgtctttgt ttatgaacca
    34261 atccaagaca gctagcaata tcatgtttat gcttgatttg gggaatcatt tagatcagtg
    34321 gtccttgaaa aaaactgcaa cagatttaga acagagtctt cttgcaaaag agagcgatgt
    34381 attcctagta cagggcgata cggttgttag tataaagagt tccgatgttc aaataggaga
    34441 tgtcttgatc ttatctcaag gaaatgaaat tctgtttgat gggcaagtag tttcaggttt
    34501 aggtatggtc aacgaaagtt ccttgacagg agagagtttt ccagttgaaa aaagagagtc
    34561 tgatttggtt tgtgcaaata cagtattaga aactggagag ttacgcattc gtgtaacaga
    34621 taatcagatg aacagccgta ttttacagct gattgagttg atgaagaaat ctgaagaaaa
    34681 caagaaaacg aaacaacgct atttcatcaa gatggcggat aaagtcgtca aatataattt
    34741 cttgggggct gggctgactt acctattgac aggttctttt tctaaggcta tttctttcct
    34801 attggtcgat ttctcctgcg ctttgaaaat ctctactcct gtagcttatt tgacagttat
    34861 caaggagggg ttgaaccgtg aaatggtgat taaggatgga gatgttctgg agaaatatct
    34921 ggaagttgat actttcttgt ttgataagac aggaacaatc acaactagtt atcctatagt
    34981 tgaaaaggtg ttaccttttg gagactatag tgaggaagat attctcagaa tcagtgcctg
    35041 tcttgaggaa cacatttatc atcctattgc taatgccatc gtcaagcaag ctgagataga
    35101 gggaattgaa catgaggaaa tgcatgggaa actccaatat atcgcaagca aggggatcaa
    35161 atctcatata gatggccaac cagttcttat tgggaattat gtcttgatgc aggatgagca
    35221 gattcatatc agttcagaac aaaatgcttt aattgaagag tacaagagtc actacaatct
    35281 cttattcttg gcttatcaaa atgaattgat tggaatgttc tgcattcata ctcctttgag
    35341 aaaagaagca aaaacagcct tggataaact taaggcacag gggaaaaaat tgattctggc
    35401 aacaggagac accttgatta ggacagagga attagtcaaa gatttgccct ttgatcaggt
    35461 ctatacagac ttgaaacctg atgggaaatt tgagttagta gagaaactgc agaaagcagg
    35521 tcacactatt ttgatggttg gagatggatt gaatgactca gcggctttaa ctctatcaga
    35581 tatcggtgtg gtgatgaatg agagtgcaga tatttctaag cagatgagtg atatcttatt
    35641 gttagataat cgtttggatt tcttccaaga gttggattcg ttatcatcat ctttgcaaac
    35701 actcatcaag aaaaatattc aagataccgt tgtcgtaaat agtagtttga ttggctttgg
    35761 cttatttaat tggttcagtc cttcaaatct ctctatctta cataatctaa caaccttgcg
    35821 cattgtcttg cgtagcttgt ctattaaaaa tagatagatg agagttatta acagcaaaaa
    35881 ggagttacct ttctcgaggt taactccttt gtttatagat aaatgttgaa tagtttagta
    35941 agtcaataca aagtattttt tcttcccacg acggataaca gtcagttcat tttctaactt
    36001 atcagcgtca ctcaagacat agtcaaggtc ttggatgcgg tcgccgttta cgtagatggc
    36061 tccgttttgg acgtcttcac gggcttggcg ttttgagtta actataccag atgagacgag
    36121 cagttccacg atattgttat gttcgtctgc ctgtacttgg tagtttggca caccacgaag
    36181 tccttgtttg agctctttga cagaaaggtt tttgatgttt cctgcaaaga gttgctcagt
    36241 gatgttaagt gcttctttgt aggcttcttc tccgtgaaca agtgtaacaa cttcacgagc
    36301 caagactttt tgagccaagc gttcgtgtgg cgctgcttca aattgtttac gaatatcttc
    36361 aatctcatca agtgacaaga aagtaaagat tttcaagaag cgaacagcgt cagcgtccat
    36421 cacgttcatc cagaattggt acatttcgta tggagaagtc ttttcgggat tgagccagac
    36481 ggcatttcct tctgatttac caaatttctt accagttgca tctgtgatta gtggaacagt
    36541 gataacgtga ccagtcttgt ccgccttacg acgaagcaat tcggtaccag ctgtcatatt
    36601 tccccactgg tcagaaccac cgatttgaag agtgacatta tggtcttggt taaggacgaa
    36661 gaagtcgtac ccttgcatga tttggtaagc gaactcagtg taagaaattc ctgtttcgat
    36721 ccgtttttta acagattcct tactcatcat gtagttgacc gtgaagtatt ttccaatatc
    36781 acggaggaag tcaatgaagc tgatgctgcc aaaccagtcg tagttgttga ccatgacagc
    36841 cttgttttcg ccattttcaa agtcaagaaa acgagaaagt tgtccttgga tagacttgac
    36901 ccagccatct actgtgtctt ttgtttggag actacgttca gcatctttga aggacggatc
    36961 tccgatgaga cctgtagcac cgccaacgag cgcataaggt ttgtgacctg ctagttgcaa
    37021 gcgacgactt gtcaagattg cgacaaggtg gcctaggtga aggctgtcag cagttggatc
    37081 gtagccagta taataagaaa cttgaccttc ttctagggct ttacgcaaag cttcttcatc
    37141 agtcgtttga aatatcaaac cacgctcttt tagctcatca aaaatgtgca tgtgtctttt
    37201 ctccttttta aaattattgt ttctacctat tgtatcacaa acttgggcaa tagcctagca
    37261 gaatagggaa gaaagtggct attttattga aaatttccct tttgtggtat aatagataga
    37321 gtgaggaaat ccatgcaaaa tcaattaaat gaattaaaac gaaaaatgct ggaatttttc
    37381 cagcaaaaac aaaaaaataa aaaatcagct agacctggca agaaaggttc aagtaccaaa
    37441 aaatctaaaa ccttagataa gtcagccatt ttcccagcta ttttactgag tataaaagcc
    37501 ttatttaact tactctttgt actcggtttt ctaggaggaa tgttgggagc tgggattgct
    37561 ttggggtacg gagtggcctt atttgacaag gttcgggtgc ctcagacaga agaattggtg
    37621 aatcaggtca aggacatctc ttctatttca gagattacct attcggacgg gacggtgatt
    37681 gcttccatag agagtgattt gttgcgcact tctatctcat ctgagcaaat ttcggaaaat
    37741 ctgaagaagg ctatcattgc gacagaagat gaacacttta aagaacataa gggtgtagta
    37801 cccaaggcgg tgattcgtgc gaccttgggg aaatttgtag gtttgggttc ctctagtggg
    37861 ggttcaacct tgacccagca actaattaaa cagcaggtgg ttggggatgc gccgaccttg
    37921 gctcgtaagg cggcagagat tgtggatgct cttgccttgg aacgcgccat gaataaagat
    37981 gagattttaa cgacctatct caatgtggct ccctttggcc gaaataataa gggacagaat
    38041 attgcagggg ctcggcaagc agctgaggga attttcggtg tagatgccag tcagttgact
    38101 gttcctcaag cagcattttt agcaggactt ccacagagtc ccattactta ctctccttat
    38161 gaaaatactg gggagttgaa gagtgatgaa gacctagaaa ttggcttaag acgggctaag
    38221 gcagttcttt acagtatgta tcgtacaggt gcattaagca aagacgagta ttctcagtac
    38281 aaggattatg accttaaaca ggacttttta ccatcgggca ctgttacagg aatttcacga
    38341 gactatttat actttacaac tttggcagaa gctcaagaac gtatgtatga ctatctagct
    38401 cagagagaca atgtctccgc taaggagttg aaaaatgagg caactcagaa gttttatcga
    38461 gatttggcag ccaaggaaat tgaaaatggt ggttataaga ttactactac catagatcag
    38521 aaaattcatt ctgccatgca aagtgcggtt gctgattatg gctatctttt agacgatgga
    38581 acaggtcgtg tagaagtagg gaatgtcttg atggacaacc aaacaggtgc tattctaggc
    38641 tttgtaggtg gtcgtaatta tcaagaaaat caaaataatc atgcctttga taccaaacgt
    38701 tcgccagctt ctactaccaa gcccttgctg gcctacggta ttgctattga tcagggcttg
    38761 atgggaagtg aaacgattct atctaactat ccaacaaact ttgctaatgg caatccgatt
    38821 atgtatgcta atagcaaggg aacaggaatg atgaccttgg gagaagctct gaactattca
    38881 tggaatatcc ctgcttactg gacctatcgt atgctccgtg aaaagggtgt tgatgtcaag
    38941 ggttatatgg aaaagatggg ttacgagatt cctgagtacg gtattgagag cttgccaatg
    39001 ggtggtggta ttgaagtcac agttgcccag cataccaatg gctatcagac cttagctaat
    39061 aatggagttt atcatcagaa gcatgtgatt tcaaagattg aagcagcaga tggtagagtg
    39121 gtgtatgagt atcaggataa accggttcaa gtctattcaa aagctactgc gacgattatg
    39181 cagggattgc tacgagaagt tctatcctct cgtgtgacaa caaccttcaa gtctaacctg
    39241 acttctttaa atcctactct ggctaatgca gattggattg ggaagactgg tacaaccaac
    39301 caagacgaaa atatgtggct catgctttcg acacctagat taaccctagg tggctggatt
    39361 gggcatgatg ataatcattc attgtcacgt agagcaggtt attctaataa ctctaattac
    39421 atggctcatc tagtaaatgc gattcagcaa gcttccccaa gcatttgggg gaacgagcgc
    39481 tttgctttag ttcctagtgt agtgaaatcg gaagtcttga aatcaacagg tcaaaaacca
    39541 gggaaggttt ctgttgaagg aaaagaagta gaggtcacag gttcgactgt taccagctat
    39601 tgggctaata agtcaggagc gccagcgaca agttatcgct ttgctattgg cggaagtgat
    39661 gcggattatc agaatgcttg gtctagtatt gtggggagtc taccaactcc atccagctcc
    39721 agcagttcaa gtagtagttc tagcgatagc agtaactcaa gtactacacg accttcttct
    39781 tcaagggcga gacgataatt ctctaaatga agtggccaat caatggattg ccactttttt
    39841 cctttcgtgt tacaataagg gtatgaatca gtatcagaaa aagattgtta acggaaaaat
    39901 ttattcgctc ctatccggct taatatgggg aatctgtgga attttaggag agtacttctt
    39961 tactcattat caggtgtctt cgggctggat tacctctatg cgtttgacac tggcagggag
    40021 tcttgtactc atttggtctg caatacaatt aaaatcgcaa gtgctagata tttggcgaga
    40081 caagaaaaat tacctgccct ttttagccta tgctattttg gggatttttt cagttcagta
    40141 ttttttctat ctctgtgtag aatactcaaa tgctacgaca gcaactattt tacagtttat
    40201 tagccctgtc tttatcctct tttacaatcg cttggtttat caaaaacgag cgtcaaaaag
    40261 cgctgttttc tatgttttgg ttgccatgct gggtgtttgc ttgatggcga caaagggaga
    40321 cctctctcag ttatccatga cgccgctagc tcttataaca ggtttgctga gtgccatggg
    40381 tgttatgttt aatgttatct tgccccaacc ttttgctaag cgttatggtt ttgttcctac
    40441 ggttgggtgg gggatgattt tggcaggttt gtttagcaat gtcctctcgc cggtttatca
    40501 gctttccttt actcttgata tttggagtat cttgatttgc ctcattatcg ctttctttgg
    40561 aacggctttt gcttttttca tttccatgaa ggctgtgtcc ttggtttctc ctttggtggt
    40621 ttccgttatc agtgccagtg aacctctctc ttctgctctc ttgagtgttt tgttcttagg
    40681 attagtagtg gattggtccc tccttctagc tatagccttg attattttac ccatgatatt
    40741 tttgtctata gaagaagcga aagaaagtag ataaaaagtc ttttcttaat tctaaaagtg
    40801 tgctatacta gaatagtcaa taaaacacgg ggagatagtt gtgaagagtg tttttaggtt
    40861 gtatcggtag gggcttgctt ttaccgacag cacgttttat ctcacatccc taaaaaatca
    40921 tacctaaaaa cagacaaaaa ggtttcaaat ttgaggcctt ttttggtaga ataggtatca
    40981 ttataacgaa ccaggaggca cctatgactg ctacaaaaat gaacgctcaa gaaattatcc
    41041 aatttatcgc caatgctgaa aagaaaacca gtgtcaaagt aacctttgag gggcaactcg
    41101 caactgctgt gcctagctct gttgtcaaac taggaaatgt cctattcgga gactggaagg
    41161 acgtggctcc gcttcttgaa ggtttggtag aaaatcaaga ttatgttgtc gagcaagatg
    41221 ctcgtaattc tgcagttcct ttgctagata agcgtgctat caacgctcgt atcgagccag
    41281 gtgctattat ccgtgaccag gtggaaattg gtgacaatgc tgttatcatg atgggagctg
    41341 ttatcaatat cggtgctgaa atcggtgctg gaaccatgat tgacatgggt gccatccttg
    41401 gtggccgtgc catcgttgga aaaaatagcc acgttggtgc aggtgcagtt ttggcaggtg
    41461 tgattgagcc agctagtgct gaaccagtcc gtgtcggaga caatgttctt atcggtgcta
    41521 atgcagtggt tatcgaagga gtccaaatcg gtagtggttc agttgtcgca gcaggagcta
    41581 ttgttaccca agatgtccca gaaaacgtgg tagtagcagg tgttccagct cgtatcatca
    41641 aagaaattga tgcccaaact caacaaaaaa cagcgctaga ggatgcgctt cgtaccttgt
    41701 aattgtaaaa gtaaaaaaga ggcggaaccc tttttccagc ctctttctgc tatatcggag
    41761 gacagataga tgttagattt gattcagact agacgagatt tacaccagat accagagatt
    41821 ggcttggagg agttcaagac tcaggcttat ttgctggatg tgattgagaa attgactacg
    41881 ggcaaggatt ttgttcaaat tcgtacttgg cggacaggga ttttggtcta cctgcaggga
    41941 agtcagccgg agcgaaccat tggttggcgg acagatattg atggcctgcc tatcgtcgaa
    42001 caaacaggtc taccttttgc ttctcaacac caaggtcgca tgcatgcctg tggccatgat
    42061 tttcatatga ccattgcctt aggctgtctt gagcgcgccc ttgaggagca acctaaaaat
    42121 aatctgctct ttctatttca gcctgctgaa gaaaatgaag ctggtggtat gctcatgtat
    42181 gaggctggtg cttttggaga ttggttgcca aaccaattct atggtctcca tgttcgtcca
    42241 gatttgaaag tcggccagat tgcgactaat actcatacac tctttgcagg aacttgcgag
    42301 gtgaagatcc gtttcaaagg caaaggtggc cacgcagctt ttcctcatga agccaatgac
    42361 gccttggtgg cggctagtta ctttgtgacc caagtgcagt cagttgttag ccgcaatgtc
    42421 aacccaatcg agggagcagt ggtgaccttc ggcgtttttc aagctggaac caccaacaat
    42481 gtcatcacag acacagcttt tttacatgga actattcgtg ccttgacaca ggacatgagt
    42541 ctcttggtgc aaaagagggt aaaaacagtt gcagaagggg ttgcagctgc ctttgatatg
    42601 gaagtcgaag tggaactcaa acaaggtgga tacctacctg ttgagaacaa tccagccttg
    42661 gcgcgtgaac tgatggactt ctttgacgag aaagacggaa tcgagttgat tgatatcgaa
    42721 cctgctatga caggcgagga ctttggttat ctcctttcaa aggttgatgg cgtgatgttt
    42781 tggctaggta tcgatagtcc ctacgctctt catcaccctc aaatgagtcc taaggaagaa
    42841 gtcttagcta ttggggtggc tgcggtgtct agtttcctga aaaagaaggc agcagaatag
    42901 agggcttgtc tatgaaatcg gaattacgca agcaagtctt gcatgaaatg aaggctttat
    42961 ctcaagaaca aaaacaggct atagaccaag ctttaaccga gcgaatttta caacacccct
    43021 tttatcaaga agccaaggtc atcgcaacct acctctcttt ttctcatgag tttcaaacgc
    43081 gggaactgat tgagcaggcg ctgaaggacg gcaagaaggt tttaataccc aaaacttatc
    43141 ccaaggggcg catggacttt gtagtctatg atctgcagca gttggtaaaa actgcctttg
    43201 ccttactgga gccacaggga gatttggaag tggtggatgt atctcagatt gatttgattc
    43261 atgttcctgg cctggctttt acgacggatg gatatcggat tggatatggt ggaggttatt
    43321 atgaccgcta tctggaacat ttttctggtc atactttgag tacggttcat ccttgtcaaa
    43381 ttcaggactt tatacctgaa aaccatgata ttcctgttca ggaggtatta attgatgaag
    43441 gaaatctttg atagacgtta ccctgtgacg agtttcttcc tcttagtgac ggccttggta
    43501 tttttactaa tgttggtcac tgcaggcgga aactttgaca gggcagatac attatttcga
    43561 tttggagcca tgtatgggcc agctattcgc ctctttcccg agcaggtttg gcgtctcttg
    43621 tctgccattt ttgttcatat tgggtgggaa catttcattg ttaatatgct ttcactttat
    43681 tatcttggaa ggcaggtaga ggagattttc ggctctaagc agttcttttt tctctatctc
    43741 ttatcaggaa tgatgggcaa tctctttgtt tttgtattta gtcctaaatc cttagcagca
    43801 ggcgcctcta cctctcttta tgggctattt gccgcgatta tcattcttcg ctatgcaacg
    43861 cgtaatcctt atatccagca gttgggccaa tcctatatga cactttttgt ggttaacatt
    43921 attggaagtg ttctgattcc agggatcagc ctagcaggcc atatcggtgg agcagttggt
    43981 ggcgcatttc tagcagttat ctttccagtt agaggagaaa aacggctgta taacaccagc
    44041 cagagattag gagcggtagt cttgttcgta ggactcgcca ttttgctttt ctacaaggga
    44101 atgggaatgt gacgaagttg aaagaaaatt tgtgtaatga aaaaagataa ggcatttttt
    44161 gaaccttatc tttttatttt attccttctc agtcaattct tttccaagtt ggatgaggta
    44221 attcttcaaa tcatctttga cttgtggatg tttgagggcg tagtcaatag atgttttcat
    44281 aaagccaaac ttatccccaa cgtcgtaacg agctcctgta aatttacggg caaaaacacg
    44341 ctgtgtttta ttaagagtat cgattgcatc agtaagttgg atttcatttc cagcaccagg
    44401 agcttgcttt tcgagaatct caaaaatttc tggtgtgagt agatagcgac cgatgattgc
    44461 caaatcactt ggagtctcct cgggagctgg tttttcaaca aaggtttcaa cactgtaaag
    44521 accatctttt ccttcgtctt gaggagcaat gactccatat gatgaaacgt cttcgtgtgg
    44581 tacgggcatg acagcaatgg ttgatgcgtg tgtcttttcg taatcattca tcagttgttt
    44641 tgtcaaagga acggccttct cgtctgtgat gtccatcaag tcatcaccca gcataacaac
    44701 gaagggttca tttcctacaa aagctttggc ttgtaagaca gcgtctccaa gaccacgagg
    44761 gtgagtttgg cggatgaaat gaaggcgcat gccagttgct tcatctacca attttaacaa
    44821 atccgttttg cctttttcct taagattgta ttcaagctca aagtttgaat caaagtggtc
    44881 ctcaatagaa cgttttgatt taccagtgac aactagaata tcttcaatac ctgatttgag
    44941 agcctcttcc acgataaact ggatagttgg tttgtctacg attggcaaca tttctttggc
    45001 aagggccttg gttgctggta aaaatcgagt tcctagtcca gcagcaggga taactgcctt
    45061 tctaactttt gatgtcataa aaatcctttc tatagagggt taagaccact cattttctgc
    45121 tttaaattca ttgttcatga tgtcataaat ggcatctttg atattggttc cgtgataaat
    45181 aacttggtaa atagcctgtg taatgggcat atagactcca agttcttggg ctagttcata
    45241 ggctgctcga gtcgttgaaa ttccttcgat taccatgccc atattagctt ctatatcagc
    45301 tagggattct cctcgtccga gagcatctcc agctctccag ttacgagagt ggatggaagt
    45361 tcccgttacg atcaaatctc ccacaccaga taagccgcta taggtcaatg gactggcccc
    45421 gagtgctacc cctaggcggg tgatttctgc taaacctcga gcgatgatgg ctgccttagc
    45481 attatcacca aatccaagac catgtaaagc tccagcaccg acagcaataa tatttttaag
    45541 agcaccagca gtttcaaccc cgataacatc cgtattggta taaagtcgga agtagtgatt
    45601 actaaatagc tcctgaacgt attgagctgt ttgtaaatct ttagaagcag cagttattaa
    45661 agttaggtca cgcacaatgg tctcttctgc atgactaggc cctgaaacag cgacgatatc
    45721 actacggaga tgttcaggaa tttcttcttc aagaatggtt gataatcgtt tatggctatc
    45781 aggttctaat ccctttgatg cgtgcatgat gataacctta tggtccaagg tttgtgcaac
    45841 ttgctgggca acaagtcgtg tcacttttgt tgggacaaca aacaaaatcg catccacatt
    45901 tttcaatgtt tctgctaagt cggtgtaggc aatgatattt tcgtctagaa cgacatcttt
    45961 aaagtagggc ttattagtat ggtgtgtatt aatttcattg atttgctcgg gaagatttcc
    46021 ccaaatacgt acctcgtgtc cattgtcatt taagacttgt gaaagggcgg ttccccaaga
    46081 accaggcccc aagacggcga cggtttgttt ttccatgatt tcctccttga tagatttctt
    46141 tctcttatta tatcatattc taggggattt tgcacttgca ttactggggt atggtggaaa
    46201 aatacacaaa gatcgagatg aagggataaa ctcttagtct ttagttaaag tgagaagaaa
    46261 tctgatagat agtttgattc agtatatgct ataaatagag gtaaacaact caggaggttc
    46321 ttgtaggttg cgaaagtttg gcgaaaaaat taaaagatta cgtttggcta aaaaaatcag
    46381 tcgttcagaa ttttgtggtg atgagtctga attaagtatc cgtcaattaa ttagaattga
    46441 aaatggagaa tccagaccaa cactaacaaa gttaaaatat atcgctgaac gtttgggggt
    46501 tgaagattac aagttgatgc caagttatat agagttggat aaggaatacc tagaattgaa
    46561 gtatttcttg atgaggactc ctacatacga agatgaaact atcgcccaaa agaaagagag
    46621 tgttttgata agatttttga agagtattat gataggctac ctgaggaaga aagatttatc
    46681 atcccaaatt attcatatct ggcactaacg aactacacag ttcaaaaatt accagaaaag
    46741 ctagttgaaa tactgtcctt ctggtgattt tgcttaattt ctgatgttcg agacataatt
    46801 gaggagattt gtcttgattt tttcctaaaa aagggcagac tcctcccttg gtttgatgct
    46861 cgatttttaa aataaggtga cttattctgt taggcatgtt ttcccctgcc ctctagctct
    46921 atatggaaca gggagtatca gatttatctg gcagattgta tcaaataagg cttgaaactg
    46981 ttttgaagag gcatatagac ttgagaattt gagaatatgt cgtctagcag tagagacata
    47041 ttttccggca atatgaagga agagacgtcg aaaacgcttg atagtcaagg cctttacttc
    47101 atcaccagct agctgcttta aaaagaggta gagattataa gccagacagc ccatcatcat
    47161 acgtacttca ttcttaatca tggtcgaact atctgtctta tccccaaaga atcctgcttt
    47221 cctttctttg ataaagtttt cagcattccc tcgttcacga tagaattgaa acagctcctc
    47281 actatctaca ctgcttaaat tgttcaaatg aactttttta caaccataaa aaagagcact
    47341 taatcgtact cttctctttt aaggattagt tgaattaatt caaatccact agttctcctg
    47401 tttctaggta gactaggcgt tcacaaatgt tagcaatgta atcagcgaag cgttccagat
    47461 gccctatgat ataaaggtat tgtgttccat tgggaattga ggtttcttgg tctttcataa
    47521 gtccaatgat ttcctttgat aaggcataat aatattggtc aatctgttca tctttttgag
    47581 caatactaat agcttttgag gcttggtgca aaggaaaggc aaccaataaa tcggctagca
    47641 tgctgaggga taatttaccc atttggtgta actgttcttc gtcaggggct agttgatttt
    47701 cttttagttg caaaacagct ttggcaatgc ctgccatatg gtctcccata cgttcaaggt
    47761 ctgaacaaga agacatgatg ctaatcacaa atcgaaggtc agacacttgt ggctgctgca
    47821 aggccaacaa acgggcacag gtcaattcga tagcgctttg accttggttg atagcatgat
    47881 ccttattgat aattagctct gccatctcct tgtctttgga ggctaaggcc agtaaggctt
    47941 ttgaagctgt ttcaaggaca agttgcccta gtcctaaaaa ggattgttct aattcatgca
    48001 attctaagtc aaattgattt ctcataggtt tttccttcct tatccgaacc gtcctgaaat
    48061 atagtcttct gtgcgctgat cttttggatt ggtaaacacg tcaacggtat ctccaaattc
    48121 gcaaatttct cctgttaaga aaaaagcagt tttatctgaa atacgtgaag cttgttgcat
    48181 gttatgggta acaatgataa tcgtataatc tttttttagt tgctgaatga ggtcttcaat
    48241 ttttaaagtg gagatagggt ctaaggctga agtcggctca tccattaaca gaatatcagg
    48301 ttctactgct aaagctcgcg caatgcaaag gcgttgctgc tgaccgccag ataaggacat
    48361 ggcactcttt ttaagatcat ctttgacttc ttcccaaatg gctgcccctt ttaaagattt
    48421 ctccactaag gcatctaatt gttttttgtc tcgaatacca tgtgtccttg ggccataagc
    48481 cacgttatca tagatagaca tggcaaaggg attaggctgt tgaaaaacca tccctacacg
    48541 cttacgtagc tgattaaggt tgaatttgct actataaata tcttgctcat ctaagaggac
    48601 ttggccttca atatggcaag aaggaaccaa atcgttcatc cggttaaggg tttttagaaa
    48661 agttgatttg ccacaaccag atgggcctat caaggcagta atctgccttt ctggtaattg
    48721 aatcgaaata ttttttaagg cttgaaaatc cccgtaaaat aagtctaggt gtctaactga
    48781 aaatgttccc atactaggaa gctcctttca caagttttcg agataataag cttgatagag
    48841 tatttatcat taaaacagta ataatcaaaa tcacaccggt agcataggct tcattgacat
    48901 gtagcccctc acttgacagc atatacatat gcagggctag agaacgacct gaagacatga
    48961 gactacttgg cgtattggta gaggtaccta atgtatacat gagggcagct gtctcaccaa
    49021 cgatacggcc aatagctagt atcactccag ctaaaatacc tggcatggca actggtagaa
    49081 caattctaaa aacagtccgt aacttacctg ccccaagtcc ataacttgct tgacgcatgc
    49141 tatcactaac agataaaagg gcttcttctg ttgagcgaat aatgactggc aacaccatga
    49201 tgactgaggt taagattcct gataacagag agtattgaaa acctaagaag actacaaaga
    49261 agagcatgcc aaacagacca aaaacaatgg aaggaatccc agacaaggta tctgaggcca
    49321 atcgcatgat tttaacacaa agggaatctt tttttgtata ttccacaaga taaaaaccag
    49381 caaaaatccc tatgggcaag gctaaaagaa gagcaccaaa gaccagaata acggtggaaa
    49441 taatcgctgg cataagggaa atgttctcag aagtataagt ccaagaaaag agggatagac
    49501 ttagatgagg taagcctttg atgaggataa aaccaatgat taaaaagaga gagccaaagg
    49561 ttaaagctga aaaacaataa acgagaagtt ttagcaggta tttactcata agatgatttt
    49621 cctttcaagt aggcaaagta ggcattaatc aagagaataa ggaaaaagag aactgctgag
    49681 gttgcaataa gggcttccct atgctgacct gatgcgtaag ccatttccag aacaatattg
    49741 gttgttaagg ttctggttcc tgaaaagagt ccacttggaa taatcggctg gttgcctgcc
    49801 accaagataa ctgccatggt ttcacctact gcgcgaccga ttcctaaaat aactgctgat
    49861 aaaataccag atctcgcagc tggcaagatg acactaaaaa tactccgttc atgactagct
    49921 cctagagcca agctaccaga ataatacgtt ttgggaactg ttcggatagc agattctgac
    49981 aaactgataa tagttggcaa aatcattatt cctaatagta acgaagcggt taggacactc
    50041 atgccatttc ctaaaaagct tctaatccaa ggcaccaata attgtaggcc gaaaaaacca
    50101 taaacaatag atggaatggc tgccatcaag ttgatagctg attttaagaa gccatagacg
    50161 ggctttggac aataataaac cataaacacc gatgtcaaga tgcctgttgg caccccaatc
    50221 acaatcgctc ctaaggtaat taataaggaa ccaacgatca ttggtaaaat accatagctt
    50281 gccggaatgt tcgttggcga ccaatcactg cctaataaaa aacgggcaaa gccgtagtta
    50341 gctatgaaag gtaagccatt actaaaaata aagaaacaga ttagcaaaat agctacaaca
    50401 gctactgttg cactcatgaa aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt
    50461 gtcacatctt gtcctttcta gtgaagaaag taagggagat acgacacctc cctacttgcc
    50521 ttctttatct tattgtacga tgaaacgtct gcatctcttt agagatttat ggagcaaaca
    50581 ttttatttaa tcttgtccca ggtggttaat ttgccactaa aaacgtctgc aagttcagcc
    50641 atactgactt ggcttgcctt attgtcatta ttgaccacaa cagcaatacc gtctaaagca
    50701 atagcatcat gggtgagact cttaccttct tcaggagtta attccctaga aaccatacca
    50761 atatcagcgg ttttctcctt aacagcggta atacctgctg aagacccatt agaggtaata
    50821 tcaatcgtaa cttctggatt ttctttttta taagcttctg ctaatttttc cattaaagaa
    50881 gatactgaag tggaacctac aacagacaac ttgcctgata agtgttggct tgtatattct
    50941 gtggtttcag ttttagcttc aataaattta ttatctgtga ccacttgttg accttgtttg
    51001 gagtggataa agctgataaa atcttgacct agcttggaaa gattagaaga ccaaacaatg
    51061 ttgaagggac gttgaagagg gtattcacca tctaaaactg tgtctcgact agccttgaca
    51121 ccatcaatct ctaaagcctt gacagatttc gttaaagatc ccaaggagat gtagccgata
    51181 gcattagcat tcccttgaac tgctgagaga acaccttctg tactattttg aatcacagct
    51241 gttttggcag tgttgtcaat ttttttatca ccgtcttttt tgagaatccc tgtgatttct
    51301 gtgaaggcac cccgtgttcc agagccattt tctcgtgaaa tcacctcaat cgttcctgaa
    51361 gctgactgtt tggaagcagc tgactgattg ccacaggcaa caagcccaaa tcctgataag
    51421 ccaatggctg caagagtaag catttttttg aatttcataa taatcacctt tatctctatg
    51481 tatttttctt gtgtaggctt actacattta tagtctaaca agtctttgta aaggtttatc
    51541 cctgattcat gtaaagattg tgtaaagaat caaaaaaagc cacttttgaa aaatggctgc
    51601 tcctaaaaat agctttaaaa attattagtc ctgtgcgaaa gattggttag gaagaaaaat
    51661 cgtgaagcaa ctgcctctgc caagctgact cgtcaccgtg acttggccac ctaataattg
    51721 actgagttct ttgacaatgg caaggccaag accagtgcca ccagtttgtc tgcttcgacc
    51781 tttattaact cggtaaaaac gttcaaaaat acgatcctgc tctaattgac taataccaat
    51841 ccctgtatct gatacagaaa tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat
    51901 ttttccccct tgttcagtgt aacggatggc attggataaa agattgagta agatttggga
    51961 aagtaattga ctatctgata cgagggtgac atcatctggc acctgcacct ttagctgtaa
    52021 atccttcttc ttgagctgag gttgcaagct ttgagtcaaa tcctgtacaa attctgccaa
    52081 agaaagggtc gtccattgta taggcatttg ttgagcctta gataaggtaa gaagatgctc
    52141 aacaatatgc tcaagacgca aactttcttt gtaaataatg tctagaaagt catccttgag
    52201 cgcttcttct tcagctgaca tccccttaat ggtttcagca aagcccttaa tcgaagtaac
    52261 tggtgtcctc aattcatggg aggcatttga gacaaaggct aaatttaact tttcataagt
    52321 tctaatcgtt gttaaatcat atagcaagac gagcacagct tccacagatt gggtggggct
    52381 aaaaacggga actgctgtta cttctaaaat caagtcaccc tcatgaaacc cacttacttc
    52441 ttgttttaac cttgtttttt gatcaaaggc ttggtgaact aaatttcgaa tatccatccg
    52501 tttgaggtca tcaagtgaac ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga
    52561 gcgactggat aataacatct gaccttgagc ggaaactaaa aacgtcccca tggttaggtg
    52621 cgacagaaga acctccattg tttcggctag gtccttgtat tgctgatcct gttgggagac
    52681 tttggttttt aggccagaca catactgagc caaagacttt aagtcttctt gccctttttc
    52741 taaaaagtat tcactactgg tcaagagagg ttggtgcaag gtctcaaaag caacttccca
    52801 tttccaaagg caaaagagcc agtagccacc ttgtcccaaa gaaagggcta gaagaaagag
    52861 accgatgcct ttactgatcc aagttaatgc catccctgca atcagaatga ggctaacact
    52921 tagattgact agccaaaatt gaaggtagcg tttcatctat aactccttga acttataacc
    52981 ataaccccga atggttcgaa taaattgagg ggctttagga ttgtcttcaa ttttttccct
    53041 caacttacca atatgaacgt ccaccaaacg tgtttcctgc ccaaagtcat acccccagat
    53101 acgttccaaa agacgctctc tagtcagtgt catgttggga tgtttcataa gatagagcaa
    53161 gagttcaaat tcttttgggg tcaaactcag taacttattc gccttgtaga cttcatgacg
    53221 ctcagggtat actttcaagg tcccaaatag ccaagaatcg tcagcgatat tatctgaatc
    53281 atctccttct tgttctcctt tagttcgcct gaggacagcc ttgacacgcg ccagcaattc
    53341 tctagggcta aaaggcttgg tcaggtagtc atcagcccct aattccaagg ccaaaacctt
    53401 atcaaattca tcacttttcg cagaaaccat cataattgga gttttgacgc ctttggctct
    53461 cagccgctta caaacttcca tgccatctaa ttgtggtaac atgatatcaa gcaagataaa
    53521 atcaaagggt tctgtttctg ccaaagctaa ggccttccgt ccatttgtta ccaattgagt
    53581 agaaaagcct tccttactta aatggtagtc aagcaatttc agaatgtgtt cttcatcatc
    53641 cactaataag acttgttttg tcatctatta tctcctattg gtaacattat aacacaatta
    53701 tcagaaatcc taacattgct aaatcagatt aaatttgctt atcaagacta gtatctggtc
    53761 aaacgctcaa tcatctcctt gtgctctgga taggtcgcca gtagatctac cctttcaaat
    53821 aattcaaaat cctcaaattc aaaaccagga gcaacaagac aagaaaccag agcatcatcc
    53881 ttatcaactg ttgatcccca aatagtgccc ttaggaacac agtagtgaag ttgttgccct
    53941 ttggatatgt ccaggcctaa agtgactgct tcgtagtgac catctgctgt gatcatgtga
    54001 acagtaagtg gggatcctgc atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa
    54061 tgtgaaggat tcgtttcttc ttaataagaa ataaatactg gtataaagcg cccttccctt
    54121 accagcaagg tttatggtgt ctgaagcttt ttttgtttgt ctaaaatagc caccttcaac
    54181 atggggagct aactctagag ttcttatcaa gtcttcttta tccgtcggag ccaatgggtt
    54241 gaagtaactc ttgttcaaag tggttttacg atttcaagaa ctcctctcag ttctgaggac
    54301 acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc ctaaaaaaag aattagcgaa
    54361 ttattctggt aaaaaaaatg ccacgctatg aaggctcaag cgattgtcac aagtcaaggg
    54421 agaattgttt ctttggatat cgctgtgaac tattgtcatg atatgaagtt gttcaaaatg
    54481 agtcgcagaa atatcggaca agctggtaaa atcttggctg acagtggtta tcaagggctc
    54541 atgaagatat atcctcaagc acaaactcca cgtaaatcca gcaaactcaa gccactaaca
    54601 gttgaagata aagcctataa ccatgcgcta tccaaggaga gaagcaaggt cgagaacatc
    54661 tttgccaaag taaaaacgtt taaaatgttt tcaacaacct atcgaaatca tcgtaaacgc
    54721 ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg attctagttt
    54781 tgcaggaagt ctattatttg gttaggtgaa ttagtgaagc gtttaggcaa gtgtctctgg
    54841 ttacgacgtc atggcctcta aatcgattat atttaggggt catgactagt gaagcagtta
    54901 gctagttcgc atataagcgg ctagcgtcta acaattagga actttagttc caataacttt
    54961 aagattacga cgttttagga cataaatcga tcatatttat gtcctaaaac tagtgaagcg
    55021 cctagccaaa gtccgaatag gatttggcgt tagttactta gattgctttg caatcaagta
    55081 actttggcga tttacatctt ctctggcgct tctactccaa gcaagcgaag ggcttctttg
    55141 agaacgactg cggttgcgta gctgagggct agacggctgt cgcgttctgg gctttcatcc
    55201 aagatacgtg tatgtgcata gtatttgtta aaggattgag ccaggctaat tgcaaattta
    55261 gcaatgatag aaggttcaaa gttatctgcc gcacggttga taatacgtgg gaagtcttga
    55321 atgagtttaa tgatttccca gctttcagta tcattcaagc tatagttgcc agctgtttct
    55381 ggtttgaaat cggctttgcg taagatagat tggatacgag cgtaggcata ttgaacgtaa
    55441 ggtccagttt caccctcgaa ggataccata gcttctaggt cgaagtcgta tccatttgta
    55501 cggtcagttt tgaggtcata gaatttaatg gctccaaccc caacagcatg tgctacttgg
    55561 tctttgtttt ctagttcagg atttttagcc tcgatttgga ccttggcacg gctaacagcc
    55621 tctgcaacag taggctctag caagatgaca ttccctttac gagtagagag cttcttccct
    55681 tcttttgtaa ccagaccaaa aggaacgtgg gtaatgtcgt cactccaatc gtagcccatc
    55741 tcttgcaaga cagctttgag ttgtttaaag tgggcagatt gctcttgacc aacgacgtag
    55801 atagatttag caaattggta ttcattttta cggtagaggg ctgcagccaa gtcacgtgtg
    55861 atatagagag ttgcaccatc agacttcttg atgagggctg gatgttcaat tccatatttc
    55921 tcaagattca caacttgggc accttctgat tcaagaagta gtcctttttc agaaagaatg
    55981 tctacaactg catccatctt atcattgtag aaggcttctc cgttatagct gtcaaattca
    56041 accttcaatt cattgtaaag gcggttaaat tccactaaac tttcatcgcg gaaccattgc
    56101 caaagagcga gagcttcctc atctccattt tcaagtttac ggaaccattc gcgcgcttct
    56161 tcatccaagc tagggtcatt ttcagcttca gcgttgatgc ggacatagag tttaaggagt
    56221 tcatcgattg gatgagcttt tacagcttct tcgtcgcccc attttttgta ggcaacaatc
    56281 aacatcccaa attgtttacc ccagtctccc aaatggttga ccttgaccgt ttgataaccg
    56341 attttttgga aaatatgtga caagctatct ccgataacag ttgaacgcag gtggccaata
    56401 gaaaatggtt tagcgatatt cggactagac atgtcgataa caacattttc ttgtttgcca
    56461 atattttggt cagcatagtg ttctttttca gtggtaacag cttgcaatac ttgagcagaa
    56521 atggcagatt tatcaaggaa aaagttaacg taaggtcctg ttgcgacaac tttttcaaag
    56581 gcttggctgt tcattttttc agccagttca gccgcaatca tttgtggtgc tttacgttcg
    56641 acttttgcaa gagaaaaagc agggaaagca atgtctccca tttctgagtt tttaggggtt
    56701 tccagtaact ttaaaatagc ctcttggtcc aggctatcaa tgatgctaga taattcgcta
    56761 gcaatcaatt cttttgtatt cattaagagc tcctttttgg acttttctac tattttatca
    56821 caattttaaa gaaagaagaa aaaatttttg aaatctcctg tttttttggt ataatatggt
    56881 tataaatata gttataaata tgcacgcaag aggattttat gagaaaaaga gatcgtcatc
    56941 agttaataaa aaaaatgatt actgaggaga aattaagtac acaaaaagaa attcaagatc
    57001 ggttggaggc gcacaatgtt tgtgtgacgc agacaacctt gtctcgtgat ttgcgcgaaa
    57061 tcggcttgac caaggtcaag aaaaatgata tggtgtatta tgtactagta aatgagacag
    57121 aaaagattga tttggtggaa tttttgtctc atcatttaga aggtgttgca agagcagagt
    57181 ttaccttggt gcttcatacc aaattgggag aagcctctgt tttggcaaat attgtagatg
    57241 taaacaagga tgaatggatt ttaggaacag ttgctggtgc caatacctta ttggttattt
    57301 gtcgagatca gcacgttgcc aaactcatgg aagatcgttt gctagatttg atgaaagata
    57361 agtaaggtct tgggagttgc tctcaagact tatttttgaa aaggagagac agaaaatggc
    57421 gatagaaaag ctatcacccg gcatgcaaca gtatgtggat attaaaaagc aatatccaga
    57481 tgcttttttg ctctttcgga tgggtgattt ttatgaatta ttttatgagg atgcggtcaa
    57541 tgctgcgcag attctggaaa tttccttaac gagtcgcaac aagaatgccg acaatccgat
    57601 ccctatggcg ggtgttccct atcattctgc ccaacagtat atcgatgtct tgattgagca
    57661 gggttataag gtggctatcg cagagcagat ggaagatcct aaacaagcag ttggggttgt
    57721 taaacgagag gttgttcagg tcattacgcc agggacagtg gtcgatagca gtaagccgga
    57781 cagtcagaat aattttttgg tttccataga ccgcgaaggc aatcaatttg gcctagctta
    57841 tatggatttg gtgacgggtg acttttatgt gacaggtctt ttggatttca cgctggtttg
    57901 tggggaaatc cgtaacctca aggctcgaga agtggtgttg ggttatgact tgtctgagga
    57961 agaagaacaa atcctcagcc gccagatgaa tctggtactc tcttatgaaa aagaaagctt
    58021 tgaagacctt catttattgg atttgcgatt ggcaacggtg gagcaaacgg catctagtaa
    58081 gctgctccag tatgttcatc ggactcagat gagggaattg aaccacctca aacctgttat
    58141 ccgctacgaa attaaggatt tcttgcagat ggattatgcg accaaggcta gtctggattt
    58201 ggttgagaat gctcgctcag gtaagaaaca aggcagtctt ttctggcttt tggatgaaac
    58261 caaaacggct atggggatgc gtctcttgcg ttcttggatt catcgcccct tgattgataa
    58321 ggaacgaatc gtccaacgtc aagaagtagt gcaggtcttt ctcgaccatt tctttgagcg
    58381 tagtgacttg acagacagtc tcaagggtgt ttatgacatt gagcgcttgg ctagtcgtgt
    58441 ttcttttggc aaaaccaatc caaaggatct cttgcagttg gcgactacct tgtctagtgt
    58501 gccacggatt cgtgcgattt tagaagggat ggagcaacct actctagcct atctcatcgc
    58561 acaactggat gcaatccctg agttggagag tttgattagc gcagcgattg ctcctgaagc
    58621 tcctcatgtg attacagatg ggggaattat ccgaactgga tttgatgaga ctttagacaa
    58681 gtatcgttgc gttctcagag aagggactag ctggattgct gagattgagg ctaaggagcg
    58741 agaaaactct ggtatcagca cgctcaagat tgactacaat aaaaaggatg gctactattt
    58801 tcatgtgacc aattcgcaac taggaaatgt gccagcccac tttttccgca aggcgacgct
    58861 gaaaaactca gaacgctttg gaaccgaaga attagcccgt atcgagggag atatgcttga
    58921 ggcgcgtgag aagtcagcca acctcgaata cgaaatattt atgcgcattc gtgaagaggt
    58981 cggcaagtac atccagcgtt tacaagctct agcccaagga attgcgacgg ttgatgtctt
    59041 acagagtctg gcggttgtgg ctgaaaccca gcatttgatt cgacctgagt ttggtgacga
    59101 ttcacaaatt gatatccgga aagggcgcca tgctgtcgtt gaaaaggtta tgggggctca
    59161 gacctatatt ccaaatacga ttcagatggc agaagatacc agtattcaac tggttacagg
    59221 gccaaacatg agtgggaagt ctacctatat gcgtcagtta gccatgacgg cggttatggc
    59281 ccagctgggt tcctatgttc ctgctgaaag cgcccattta ccgatttttg atgcgatttt
    59341 tacccgtatc ggagcagcag atgacttggt ttcgggtcag tcaaccttta tggtggagat
    59401 gatggaggcc aataatgcca tttcgcatgc gaccaagaac tctctcattc tctttgatga
    59461 attgggacgt ggaactgcaa cttatgacgg aatggctctt gctcagtcca tcatcgaata
    59521 tatccatgag cacatcggag ctaagaccct ctttgcgacc cactaccatg agttgactag
    59581 tctggagtct agtttacaac acttggtcaa tgtccacgtg gcaactttgg agcaggatgg
    59641 gcaggtcacc ttccttcaca agattgaacc gggaccagct gataaatcct acggtatcca
    59701 tgttgccaag attgctggct tgccagcaga ccttttagca agggcggata agattttgac
    59761 tcagctagag aatcaaggaa cagagagtcc tcctcccatg agacaaacta gtgctgtcac
    59821 tgaacagatt tcactctttg atagggcaga agagcatcct atcctagcag aattagctaa
    59881 actggatgtg tataatatga cacctatgca ggttatgaat gtcttagtag agttaaaaca
    59941 gaaactataa aaccaagact cactagttaa tctagctgta tcaaggagac ttctttgaca
    60001 attctccact tttttgctag aataacatca cacaaacaga atgaaaagga gctgacgcat
    60061 tgtcgctccc ttttgtctat tttttaagga gaaagtatgc tgattcagaa aataaaaacc
    60121 tacaagtggc aggccttggc ttcgctcctg atgacaggct tgatggttgc tagttcactt
    60181 ctgcaaccgc gttatctgca ggaagtatta gacgccctcc ttactgggaa atatgaagct
    60241 atttatagta tcggggcttg gttgattggt gtggccgtag tcggtctagt tgctggtgga
    60301 ctcaatgttg tcctcgcagc ctatattgcc caaggagttt catccgacct tcgggaggat
    60361 gccttccgta aaattcaaac cttttcttat gctgatattg aacaatttaa tgcgggaaat
    60421 ctagtcgttc gaatgacaaa tgatatcaac cagattcaga acgttgtcat gatgaccttc
    60481 caaattcttt tcagacttcc cctcttgttc atcggttcgt ttatcctagc ggttcaaacc
    60541 ttaccttctc tgtggtgggt gattgttctc atggtagtct tgatttttgg tttgactgct
    60601 gtcatgatgg gaatgatggg gcctcgtttt gctaaatttc aaacccttct tgagcgcatc
    60661 aatgccattg ccaaggaaaa tttacgtggc gttcgtgtgg tcaagtcctt tgtccaagaa
    60721 aaagagcaat ttgctaagtt tacagaggtc tcaaacgagc ttcttggtca aaacctttac
    60781 attggttatg ccttttcagt agtggaaccc tttatgatgt tggttggtta cggggcggtc
    60841 ttcctctcta tttggctggt cgcgggaatg attcagtcgg atccgtctgt tgttggttcc
    60901 atcgcttctt ttgttaatta cctaagccag attatcttta ccattgttat ggttggattt
    60961 ttgggaaatt ctgtcagccg tgccatgatt tccatgcgtc gtattcgaga aattcttgac
    61021 gcagagccag ctatgacctt caaggatatc ccagatgaag agttggttgg aagtcttagc
    61081 tttgaaaatg tgacctttac ctatccaatg gacaaggaac cgatgctgaa aaatgtgagc
    61141 tttactattg aacctggtca aatggttggt gtagttggag cgactggtgc aggaaagtca
    61201 accttggctc aattgattcc acgtctcttt gatccacagg acggggccat taaaattggt
    61261 ggcaaggata ttcgagaagt gagtgaagga accctgcgta aaacagtttc catcgttctc
    61321 caacgtgcca ttctttttag tggaacgatt gcagataact tgagacaggg gaagggaaat
    61381 gctaccctat ttgaaatgga gcgcgcagcc aatattgccc aggctagtga attcattcat
    61441 cgtatggaga aaacctttga aagtccagtt gaagaacggg gaaccaattt ctctggtgga
    61501 caaaaacaaa ggatgtcgat tgcgcgtggg attgtcagca atccacgtat tctgattttt
    61561 gacgattcga cctcagcctt ggatgccaaa tcagagcgct tggtgcaaga agctttgaat
    61621 aaggacttga aggggacgac aaccattatt attgctcaaa aaattagctc ggttgtccat
    61681 gcagacaaga tcttggttct aaatcaagga cgattgattg gtcaaggtac gcatgcagac
    61741 ttggttgcca acaatgccgt ttaccgtgaa atctatgaaa cacagaaatg aaagacaaac
    61801 tataagaaaa gtcaatagtt ttatctaaac tatttcttat ttcaatttga tgatttggcg
    61861 atgattttag agcacggcaa aaagcccttg aaaaagtcca ttttttcaaa ggtaatcctg
    61921 tgttgatttc agaaattaca tcactttttg ttcgtcaaat ggcagctctt ttttaggata
    61981 taaaacaggg ttcggataag tttttttgca aggtggatga tggctacatt gtaatgtttt
    62041 ccttgttcta acttagtctt aaaagcaggt gaaaagtgag ggcatgcttt ggcagcttgt
    62101 atgagtacct accgcagatg aggggaaccc cgtttgacca ttctttctgc taaatcaatc
    62161 tgacctgact gataaataga agaatccagt ccagcgaaag cttgtaattg agcaggatta
    62221 tcaaaggcat gaatatttcg aatctcggct aaaatgaccg cccctaaacg attctcaatc
    62281 ccagtaaccg tcgtgatgac cgagttgaac tcagccatca agtcattgac acatttttcc
    62341 gccttgtcaa tgagcctctt gtaatgtttg atgttttcat tacacgagat aaaacgtcta
    62401 tgcgttatca aactcattac caattaaaac aaatgtggtt agatcctttc ggaaattgtc
    62461 aagcgattgg aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct
    62521 ttggcagtag ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa
    62581 tttttttggc attattttaa ggtctacaag ttctcatttg tagttgtcat cctgatgatt
    62641 gttctggcga cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag
    62701 ctagccaatt tagttcaagc ttatcaaaat ggcaatccag aacttgtatg gcaaagccta
    62761 tcaggaatca tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata
    62821 tacatgtgtc tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggtctc
    62881 tttggtaagc ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc
    62941 ctgtctcatt ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt
    63001 caggtcatga gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat
    63061 gtgacgctgg ctctcatcac tattgccagc accccattgg ctttccttat gctgattttc
    63121 atcgtgaaaa tggcacgtaa atacaccaac ctccagcaga aagaggtagg gaagctcaac
    63181 gcctatatgg atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag
    63241 gatatgatgg caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga
    63301 agaatgttct caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc
    63361 atcgtcatct ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca
    63421 gccctaggtt tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc
    63481 caagttgcag cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag
    63541 gaaatgtttg atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg
    63601 caagaaagtg ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg
    63661 aaagatgtca gcatttctgc ccctaaaggc cagatgacag cagttgttgg gccgacaggt
    63721 tcaggaaaaa cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt
    63781 atttattttg atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg
    63841 ggaattgtat tgcaagattc ggtcttgttt agcggaacga ttcgagacaa tatccgattt
    63901 ggtgtgccag atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac
    63961 gactatatcg aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc
    64021 ttttcaacag ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa
    64081 gttctcattc tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag
    64141 catgccatgg aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa
    64201 accattctca atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt
    64261 aaccaccatg aacttttgaa gctaggtggt ttttattcag aactctatca caatcaattt
    64321 gttttcgaat aagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg
    64381 tttatcacag ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga
    64441 ctatcgttag cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca
    64501 aatctatgtc ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc
    64561 gcagagatca ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca
    64621 gttgtacgtg attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt
    64681 catcctcagt tttatggaga gaaaaagacc gtcgagagcg atgattacaa tctggtccgt
    64741 gacgaatttg aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca
    64801 atctgtcgcg gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc
    64861 gaaggtcact ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga
    64921 agtgtggtgg ctaagctatt tgggaaagaa agtcaggtca actcagtcca tcgtcaaagc
    64981 attaaacatt tggcacctaa tttccgtgta actgctattg attcaagaga ccaaactatt
    65041 gaagcgattg agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt
    65101 ctggttaatg aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa
    65161 cgattggaac atctggtcgt tctttttttt attttttcaa aatttttaga atgtggtatt
    65221 ttacgcaaac gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa
    65281 aacgaaggta agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat
    65341 taaatttgat tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat
    65401 gcaatcacaa gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga
    65461 cttcttggga tggttggacc ttcctgaaaa atacgatcgc gaagaatttg accgcatctt
    65521 gaaagctgct gagaaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg
    65581 atcttacctt ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca
    65641 aacaaaagaa gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tctcatctac
    65701 ttaccttgct gacttggtag agtatgttgc agacaaggac ttctcagtaa acgtaatttc
    65761 taaatcaggt acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt
    65821 taagaaatac ggtcaagaag aagctaacaa gcgtatctat gcaacaactg accgccaaaa
    65881 gggtgctgtt aaggttgaag cagacgctaa cggttgggga acatttgttg ttccagatga
    65941 tatcggtgga cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg
    66001 agctgacatc aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga
    66061 caaaatctct gaaaacgaag cttaccaata cgcagccgtt cgtaacatcc tttatcgtaa
    66121 aggctatgca actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg
    66181 gtggaaacaa ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc
    66241 agccaacttc tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat
    66301 catgtttgaa acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt
    66361 ggaagaagac cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa
    66421 aaaagcaact gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt
    66481 gactcttcca gagcaagacg ctttcactct tggttacact atatacttct tcgaattggc
    66541 aattgccctt tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc
    66601 ttataaacgt aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga
    66661 acttaacgca cgtctataat agaagaaaag agtggtttgc ccactctttt tactctcttt
    66721 atccatagaa attggactca gccaagactt gtgatataat atagaaagca aaaaggcaga
    66781 cgcctagata ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc
    66841 aacaggacta ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg
    66901 ccatcatggt ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga
    66961 ggatggtgaa cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag
    67021 tccagaatca catgagaatt atcgccagtc tgagcgtttg gacttgtatc aaaaatacat
    67081 cgaccaacta ttagctgaag gaaaagccta caaatcttac gttacagaag aagagttggc
    67141 agctgaacgt gaacgtcaag aagtagctgg cgaaacacca cgctacatca atgaatacct
    67201 tggtatgagt gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggaccat
    67261 cccaactgtt cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa
    67321 aggcgatatc gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga
    67381 cggttaccca acttacaact ttgccgttgt tatcgatgac cacgatatgc aaatctctca
    67441 tgttatccgt ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaagc
    67501 tcttggttgg gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg
    67561 taagaagtta tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa
    67621 aggttacctt ccagaagcag tctttaattt tattgctctt cttggttgga acccaggtgg
    67681 tgaagatgag attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag
    67741 caagtcacca gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa
    67801 gaatgcagac cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg
    67861 tttgactgac aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga
    67921 tgagattatc ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga
    67981 gcgcgaagtc atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact
    68041 tgaagcgatg acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt
    68101 tcaaaaagaa acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc
    68161 aggcgaaatg catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc
    68221 aattcagcat atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg
    68281 acatctggga aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag
    68341 actttgttta tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta
    68401 caggattctg tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc
    68461 tcttcaatat gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag
    68521 ataaaccacc ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt
    68581 tagagcttaa tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa
    68641 cagttaaagt cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta
    68701 atgagcaata gaagagtcag tataattctg gctcttttta ctataagtt
//
LOCUS       DAVMCG010000007        67092 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVMCG010000007 DAVMCG010000000
VERSION     DAVMCG010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67092
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.007"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..1606
                     /locus_tag="VYP66_000539"
     CDS             <1..1606
                     /locus_tag="VYP66_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV1850139.1"
                     /translation="KNVIINNIIDIINDIHAEGYLAVDISPTNFILDDFGRVRLIDLE
                     NFTNKNNTVRRAATKFMINTDCPSKICTIQQDYFALAMLSFAIMREHVLIFEGEDVLL
                     NITALDKIKFCMYSEKEIGNITKSQFNWLMYLLNLSEQEKLDRFEKMKYINDFEDKNI
                     EFHLKKVDSSFNLQIENETLINYLLSLNMNRESRILNSNEFGEFVSPISFQHGLSGYL
                     FYLSHMRDISENGRIIEWIISEGNQNKGNVYLNGCSILFGSSGYLWVLLEFYKKITSN
                     NPSRELIIDKIRDIYKDLISSYQKVEVFDFALGKSGILLSLMKYCINFNDVDSMEFIR
                     EKIEELYLYFVDEIRNVNSLKECNFAHGLAGIAYVILIYNSEFEFKVAYENSIKVFNN
                     LLENLLENEYSRLNATPTNLELSWCEGTSGILLYFELLYDKRYSNIISRFQQLAFKFN
                     LIQSSCYCHGLSSLLQTLNYQDKLNLRENVIEILLSRSKRDKNGILVFECEESSDTLF
                     DFGIGNLGIYWSILGERFPFELKKEL"
     gene            1606..2832
                     /locus_tag="VYP66_000540"
     CDS             1606..2832
                     /locus_tag="VYP66_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1850140.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            3280..3936
                     /locus_tag="VYP66_000541"
     CDS             3280..3936
                     /locus_tag="VYP66_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1850141.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            3926..4249
                     /locus_tag="VYP66_000542"
     CDS             3926..4249
                     /locus_tag="VYP66_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1850142.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            4353..5183
                     /locus_tag="VYP66_000543"
     CDS             4353..5183
                     /locus_tag="VYP66_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1850143.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            5337..6191
                     /locus_tag="VYP66_000544"
     CDS             5337..6191
                     /locus_tag="VYP66_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1850144.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            6291..7664
                     /locus_tag="VYP66_000545"
     CDS             6291..7664
                     /locus_tag="VYP66_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1850145.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            7657..8718
                     /locus_tag="VYP66_000546"
     CDS             7657..8718
                     /locus_tag="VYP66_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1850146.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            8720..9412
                     /locus_tag="VYP66_000547"
     CDS             8720..9412
                     /locus_tag="VYP66_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850147.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIVIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(9442..10011)
                     /locus_tag="VYP66_000548"
     CDS             complement(9442..10011)
                     /locus_tag="VYP66_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1850148.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVTPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            10146..10760
                     /locus_tag="VYP66_000549"
     CDS             10146..10760
                     /locus_tag="VYP66_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1850149.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            10762..12408
                     /locus_tag="VYP66_000550"
     CDS             10762..12408
                     /locus_tag="VYP66_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1850150.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            12420..13706
                     /locus_tag="VYP66_000551"
     CDS             12420..13706
                     /locus_tag="VYP66_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850151.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            13758..14291
                     /locus_tag="VYP66_000552"
     CDS             13758..14291
                     /locus_tag="VYP66_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850152.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            14369..14839
                     /gene="nrdI"
                     /locus_tag="VYP66_000553"
     CDS             14369..14839
                     /gene="nrdI"
                     /locus_tag="VYP66_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1850153.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(15132..16394)
                     /locus_tag="VYP66_000554"
     CDS             complement(15132..16394)
                     /locus_tag="VYP66_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1850154.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDAVFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(16704..17162)
                     /locus_tag="VYP66_000555"
     CDS             complement(16704..17162)
                     /locus_tag="VYP66_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1850155.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(17159..17599)
                     /locus_tag="VYP66_000556"
     CDS             complement(17159..17599)
                     /locus_tag="VYP66_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850156.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            17955..19904
                     /gene="mutL"
                     /locus_tag="VYP66_000557"
     CDS             17955..19904
                     /gene="mutL"
                     /locus_tag="VYP66_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1850157.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(20229..20696)
                     /locus_tag="VYP66_000558"
     CDS             complement(20229..20696)
                     /locus_tag="VYP66_000558"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1850158.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(20697..21902)
                     /locus_tag="VYP66_000559"
     CDS             complement(20697..21902)
                     /locus_tag="VYP66_000559"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1850159.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRIDDLIQFSKKHNIPLITIKELQEYRKAYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKIIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(21922..22557)
                     /gene="ribE"
                     /locus_tag="VYP66_000560"
     CDS             complement(21922..22557)
                     /gene="ribE"
                     /locus_tag="VYP66_000560"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1850160.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(22542..23642)
                     /gene="ribD"
                     /locus_tag="VYP66_000561"
     CDS             complement(22542..23642)
                     /gene="ribD"
                     /locus_tag="VYP66_000561"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1850161.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGSHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMTMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(23776..23890)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            24047..24640
                     /gene="ruvA"
                     /locus_tag="VYP66_000562"
     CDS             24047..24640
                     /gene="ruvA"
                     /locus_tag="VYP66_000562"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1850162.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKIAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            24650..25213
                     /locus_tag="VYP66_000563"
     CDS             24650..25213
                     /locus_tag="VYP66_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1850163.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            25210..25887
                     /locus_tag="VYP66_000564"
     CDS             25210..25887
                     /locus_tag="VYP66_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1850164.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(26024..27055)
                     /locus_tag="VYP66_000565"
     CDS             complement(26024..27055)
                     /locus_tag="VYP66_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1850165.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(27310..27993)
                     /locus_tag="VYP66_000566"
     CDS             complement(27310..27993)
                     /locus_tag="VYP66_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1850166.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(28005..28949)
                     /locus_tag="VYP66_000567"
     CDS             complement(28005..28949)
                     /locus_tag="VYP66_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1850167.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            29081..31912
                     /gene="uvrA"
                     /locus_tag="VYP66_000568"
     CDS             29081..31912
                     /gene="uvrA"
                     /locus_tag="VYP66_000568"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1850168.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQVLSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            31905..32966
                     /locus_tag="VYP66_000569"
     CDS             31905..32966
                     /locus_tag="VYP66_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1850169.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            33098..33496
                     /gene="spx"
                     /locus_tag="VYP66_000570"
     CDS             33098..33496
                     /gene="spx"
                     /locus_tag="VYP66_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1850170.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            33562..34131
                     /locus_tag="VYP66_000571"
     CDS             33562..34131
                     /locus_tag="VYP66_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1850171.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            34218..34484
                     /locus_tag="VYP66_000572"
     CDS             34218..34484
                     /locus_tag="VYP66_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1850172.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            34488..34907
                     /gene="ruvX"
                     /locus_tag="VYP66_000573"
     CDS             34488..34907
                     /gene="ruvX"
                     /locus_tag="VYP66_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1850173.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            34923..35228
                     /locus_tag="VYP66_000574"
     CDS             34923..35228
                     /locus_tag="VYP66_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1850174.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            35689..36939
                     /locus_tag="VYP66_000575"
     CDS             35689..36939
                     /locus_tag="VYP66_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1850175.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            36936..37493
                     /locus_tag="VYP66_000576"
     CDS             36936..37493
                     /locus_tag="VYP66_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1850176.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            37639..39171
                     /gene="cls"
                     /locus_tag="VYP66_000577"
     CDS             37639..39171
                     /gene="cls"
                     /locus_tag="VYP66_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1850177.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            39429..40967
                     /locus_tag="VYP66_000578"
     CDS             39429..40967
                     /locus_tag="VYP66_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1850178.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            41087..43294
                     /gene="nrdD"
                     /locus_tag="VYP66_000579"
     CDS             41087..43294
                     /gene="nrdD"
                     /locus_tag="VYP66_000579"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1850179.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            43306..43446
                     /locus_tag="VYP66_000580"
     CDS             43306..43446
                     /locus_tag="VYP66_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850180.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            43490..43996
                     /locus_tag="VYP66_000581"
     CDS             43490..43996
                     /locus_tag="VYP66_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850181.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            43989..44579
                     /gene="nrdG"
                     /locus_tag="VYP66_000582"
     CDS             43989..44579
                     /gene="nrdG"
                     /locus_tag="VYP66_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1850182.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            44576..45193
                     /locus_tag="VYP66_000583"
     CDS             44576..45193
                     /locus_tag="VYP66_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1850183.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            45459..45767
                     /gene="rpsJ"
                     /locus_tag="VYP66_000584"
     CDS             45459..45767
                     /gene="rpsJ"
                     /locus_tag="VYP66_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1850184.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            45984..46610
                     /gene="rplC"
                     /locus_tag="VYP66_000585"
     CDS             45984..46610
                     /gene="rplC"
                     /locus_tag="VYP66_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1850185.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            46635..47258
                     /gene="rplD"
                     /locus_tag="VYP66_000586"
     CDS             46635..47258
                     /gene="rplD"
                     /locus_tag="VYP66_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1850186.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            47258..47554
                     /locus_tag="VYP66_000587"
     CDS             47258..47554
                     /locus_tag="VYP66_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1850187.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            47572..48405
                     /gene="rplB"
                     /locus_tag="VYP66_000588"
     CDS             47572..48405
                     /gene="rplB"
                     /locus_tag="VYP66_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1850188.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            48509..48790
                     /gene="rpsS"
                     /locus_tag="VYP66_000589"
     CDS             48509..48790
                     /gene="rpsS"
                     /locus_tag="VYP66_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1850189.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            48802..49146
                     /gene="rplV"
                     /locus_tag="VYP66_000590"
     CDS             48802..49146
                     /gene="rplV"
                     /locus_tag="VYP66_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1850190.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            49159..49812
                     /gene="rpsC"
                     /locus_tag="VYP66_000591"
     CDS             49159..49812
                     /gene="rpsC"
                     /locus_tag="VYP66_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1850191.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            49816..50229
                     /gene="rplP"
                     /locus_tag="VYP66_000592"
     CDS             49816..50229
                     /gene="rplP"
                     /locus_tag="VYP66_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1850192.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            50239..50445
                     /locus_tag="VYP66_000593"
     CDS             50239..50445
                     /locus_tag="VYP66_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1850193.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            50470..50730
                     /gene="rpsQ"
                     /locus_tag="VYP66_000594"
     CDS             50470..50730
                     /gene="rpsQ"
                     /locus_tag="VYP66_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1850194.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            50756..51124
                     /gene="rplN"
                     /locus_tag="VYP66_000595"
     CDS             50756..51124
                     /gene="rplN"
                     /locus_tag="VYP66_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1850195.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            51202..51507
                     /gene="rplX"
                     /locus_tag="VYP66_000596"
     CDS             51202..51507
                     /gene="rplX"
                     /locus_tag="VYP66_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1850196.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            51531..52073
                     /gene="rplE"
                     /locus_tag="VYP66_000597"
     CDS             51531..52073
                     /gene="rplE"
                     /locus_tag="VYP66_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1850197.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            52091..52360
                     /gene="rpsN"
                     /locus_tag="VYP66_000598"
     CDS             52091..52360
                     /gene="rpsN"
                     /locus_tag="VYP66_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1850198.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            52645..53043
                     /gene="rpsH"
                     /locus_tag="VYP66_000599"
     CDS             52645..53043
                     /gene="rpsH"
                     /locus_tag="VYP66_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1850199.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            53235..53771
                     /gene="rplF"
                     /locus_tag="VYP66_000600"
     CDS             53235..53771
                     /gene="rplF"
                     /locus_tag="VYP66_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1850200.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            53855..54211
                     /gene="rplR"
                     /locus_tag="VYP66_000601"
     CDS             53855..54211
                     /gene="rplR"
                     /locus_tag="VYP66_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1850201.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            54229..54723
                     /gene="rpsE"
                     /locus_tag="VYP66_000602"
     CDS             54229..54723
                     /gene="rpsE"
                     /locus_tag="VYP66_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1850202.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            54695..54919
                     /gene="rpmD"
                     /locus_tag="VYP66_000603"
     CDS             54695..54919
                     /gene="rpmD"
                     /locus_tag="VYP66_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1850203.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            55064..55504
                     /gene="rplO"
                     /locus_tag="VYP66_000604"
     CDS             55064..55504
                     /gene="rplO"
                     /locus_tag="VYP66_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1850204.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            55517..56827
                     /gene="secY"
                     /locus_tag="VYP66_000605"
     CDS             55517..56827
                     /gene="secY"
                     /locus_tag="VYP66_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1850205.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            56978..57616
                     /locus_tag="VYP66_000606"
     CDS             56978..57616
                     /locus_tag="VYP66_000606"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1850206.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            57733..57951
                     /gene="infA"
                     /locus_tag="VYP66_000607"
     CDS             57733..57951
                     /gene="infA"
                     /locus_tag="VYP66_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1850207.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            57976..58092
                     /gene="rpmJ"
                     /locus_tag="VYP66_000608"
     CDS             57976..58092
                     /gene="rpmJ"
                     /locus_tag="VYP66_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1850208.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            58110..58475
                     /gene="rpsM"
                     /locus_tag="VYP66_000609"
     CDS             58110..58475
                     /gene="rpsM"
                     /locus_tag="VYP66_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1850209.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            58493..58876
                     /gene="rpsK"
                     /locus_tag="VYP66_000610"
     CDS             58493..58876
                     /gene="rpsK"
                     /locus_tag="VYP66_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1850210.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58919..59854
                     /locus_tag="VYP66_000611"
     CDS             58919..59854
                     /locus_tag="VYP66_000611"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1850211.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            59866..60252
                     /gene="rplQ"
                     /locus_tag="VYP66_000612"
     CDS             59866..60252
                     /gene="rplQ"
                     /locus_tag="VYP66_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1850212.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            60517..60783
                     /locus_tag="VYP66_000613"
     CDS             60517..60783
                     /locus_tag="VYP66_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1850213.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            60793..62130
                     /locus_tag="VYP66_000614"
     CDS             60793..62130
                     /locus_tag="VYP66_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1850214.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            62374..63066
                     /locus_tag="VYP66_000615"
     CDS             62374..63066
                     /locus_tag="VYP66_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1850215.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(63169..64804)
                     /locus_tag="VYP66_000616"
                     /pseudo
     CDS             complement(63169..64804)
                     /locus_tag="VYP66_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(64794..65885)
                     /locus_tag="VYP66_000617"
     CDS             complement(64794..65885)
                     /locus_tag="VYP66_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850216.1"
                     /translation="MSEIKIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPTNEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEDLQKDNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(65898..67019)
                     /locus_tag="VYP66_000618"
                     /pseudo
     CDS             complement(65898..67019)
                     /locus_tag="VYP66_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
BASE COUNT        20102 a        12493 c        14727 g        19770 t
ORIGIN      
        1 aaaaaatgta atcattaata atataattga tattattaat gatattcatg ctgagggata
       61 tttagcagtg gatatttctc caacaaactt tatattggat gattttggtc gtgttaggtt
      121 aatagactta gaaaatttta caaacaaaaa caatactgtt agaagagctg ctacaaaatt
      181 catgataaat actgattgtc cctcaaaaat ctgtaccatt caacaggatt attttgcact
      241 tgcaatgttg agttttgcta ttatgcgcga gcatgtttta atatttgaag gagaggacgt
      301 cttattaaat ataactgctt tagataaaat caagttttgt atgtatagcg agaaagaaat
      361 tgggaacata actaaatcgc aatttaattg gttgatgtat ttattgaatt taagtgaaca
      421 agagaagtta gaccgattcg agaagatgaa gtatataaac gattttgaag ataaaaatat
      481 agaatttcat ttaaagaaag ttgattcctc attcaatctt caaattgaaa atgaaacgct
      541 tattaactat cttctttcgt taaatatgaa tagagaaagc aggatactaa attcaaatga
      601 atttggagaa tttgttagtc caatatcgtt tcaacatggc ttatcaggat atttgtttta
      661 tttatcacat atgagagaca tttctgagaa tggtagaatt atcgagtgga ttatctctga
      721 aggaaatcaa aataaaggaa atgtgtatct aaatggttgt tcaattttat ttggttcttc
      781 cggatatctt tgggtattat tagagttcta taaaaaaatt accagcaaca atccaagtag
      841 agaattgatc atagataaaa ttagagatat ttataaagac ttgataagta gttatcaaaa
      901 agttgaagta tttgactttg ctttaggaaa gtcaggtatt ttattgagtc ttatgaaata
      961 ctgtataaat ttcaatgatg tcgatagtat ggaatttatt agagaaaaaa tagaggagtt
     1021 atatttatat tttgtagatg agatacgaaa tgttaatagt ttaaaagaat gtaattttgc
     1081 acatggtcta gctggaattg catacgtaat tttaatttat aattcggaat ttgaattcaa
     1141 ggtagcttac gaaaatagta ttaaggtatt caataatctg ttagaaaatt tgttagaaaa
     1201 tgaatatagt agactaaatg caactcctac aaatttagaa ctatcgtggt gcgaaggaac
     1261 ttcaggaatc ttactttatt ttgagttatt atatgacaaa aggtattcaa acataatttc
     1321 aaggtttcaa caacttgctt tcaaattcaa tcttatccag tcaagttgtt attgtcatgg
     1381 cttatccagt ttgttgcaaa ctctaaacta tcaggataaa ttaaatttac gtgagaatgt
     1441 gattgagatt ttattaagta gatccaaaag agataaaaat ggtattttgg tatttgaatg
     1501 tgaagaaagt tcagatacat tatttgattt tggtatcgga aatctaggga tttattggtc
     1561 tatccttggg gaaagattcc catttgaact taagaaggag ttgtgatgaa agtatttctt
     1621 caaaatagag attttaggca attaactatc aaccagtgga tttcaacgct tggggatacg
     1681 attttttatc tggccttcct gaattatgtg gcagatgcat cttttgcccc tttggcgatt
     1741 ttactcatca cgatttcaga aaccctgccc caagttctac aaatctttct gggagttttg
     1801 gcggattttc aacatcatcg tgtcttgaaa tacacagtca ttagttttgc aaaatttttg
     1861 ctttactcta tagtgtcttt atcactttca gggcagtcct tttccttgtt attagtagca
     1921 tttatttgtc tgattaacct cttgtctgac acgttgagtt atttttcagg cgccatgctc
     1981 actccgattt tcattagaat tattgggcaa gaccatctgg cagaagctat tggatttaaa
     2041 cagtcaactg ttagtttagt gaaaacaatc agtaatattc taggaggagt cttattaggt
     2101 attctatcca tccagtttat ttccttgctg aacgctctta cctttttaat cgcattttta
     2161 ggtatcctct tcataaaaac tgacctcttg aaagtagaaa aaacgattaa ctatcaagaa
     2221 ggactctctg taaaatcctt ttgccagcat ttgctccaat catcgaaatt gatatggaat
     2281 atgaataagg tgctcttggt tttgtttatt atctctacta gtcaagcagt gataaatgtt
     2341 acagttcctg tctctactct atttttgagg aatcaaccct ttttgaattt acaaacaggt
     2401 caatctcttg ccttgctatc cacttttgaa ctgtcagccc tgattgtcgg aagccttgta
     2461 agtggctatc tgcaacatac catttccata aaaacagctc tctatgcctc acttgtcacc
     2521 cagttgcttc ttctagtagg atttgccaca gttcgttttg actggattct catctttagt
     2581 accttggatg cctttttcgc aggtgttctc tctcctagat tgcaagaact cgtttttaaa
     2641 caaatacctg aggagtcaat gggagcagtt caatcctcta tcggtgccat tacggttgtt
     2701 ttacctagct tatttacaat agctttggta accattgcta ctagctttgg aactctggca
     2761 gttagctttg ttttattgct atttcttcta gttgcctttg ttatgcttct gaatattcgt
     2821 gaaagtattt agtggagaat ttctataata tatgtttgag actggattgc cagccttttt
     2881 atgatggtca aaatcaacag acttttttct cttttctgaa tgtgttataa tagactgaat
     2941 ctaaaatagt acgaaacaat tgctaaaaca tttatttata gaaattaatt ttactttccc
     3001 aatcgatttg ttctcatctt atttcaatct gctatataat agtccatgct gtggctggat
     3061 tcttttcagc ctacttatac tcttcgaaac tctcttcaaa ccacgtcagc ttcaccttgc
     3121 cgtaggtatg gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc
     3181 tgactacgtc agttctatct gcttttcatt gagtactatt aagacaatat gaggagaaag
     3241 atgaaagaaa aaggatttta ggagggggcg caggcagcca tgccaacggc tcttggctat
     3301 gtcagtatcg gcctggcctg tgggactatc ggtgcgccct atgtgacacc tgttgagatg
     3361 ggcttgatga gtctctttgt ttatgctggg agtgcccagt ttgccatgtt ggcactgatt
     3421 gtggttcaag ctcctgtggc agctattgct atgacggttt ttctaatcaa cttgcgtctc
     3481 tttttgttga gtttacacgc atcgacttat ttccgtcata ccagtctttg gtacaatatc
     3541 ggtatgtcta gtatcttgac agatgagacc tatggcgttt tgatgggtga attggcccat
     3601 acagacaagg taaatcctat gtggatgcac ggaaacaatc ttaacagcta tgtggcttgg
     3661 tttgtgggga cagtagtcgg aacggctctg ggtggcctgc taccaaatcc agaaatcttt
     3721 ggcttggatt ttgccctagt tgggatgttt attggtattt ttgcttcgca atttcagatt
     3781 atgcaaagac ggattcctgt ccgcaatctg ctcattatcc tagcagttgt tgcggtgtcc
     3841 ttctttttgc tcttgacagt ggtgtctcag tcactagctg ttctgtttgc gacgctactt
     3901 ggttgtagca tgggggtggt tttagatggt cagtaagtat cttttattag cagttatttt
     3961 ctctggcttg gtgacttgga ttctccgtat gattcccttc atcttagtca agtataaggg
     4021 cttgcctgca atcgttgagc gttttttgaa gttcttgccc gtttccatta tctttgcctt
     4081 gattctttca agcgtagtga caggtaaggt tgggagcctt cctcaaatta aatggctaga
     4141 cttcttagcc gtctttccaa cagcttgggt agcctttcgc taccgcaatc tagtcggaac
     4201 agttctcttt ggagtggtct tgattgccat cttgcgtttg gtcttttaaa ttacccataa
     4261 aaaaaactta tcacagagat agatatcata taatggcgta aatgctcttt ttctgttaag
     4321 attataaggt attctatttt ggaggaaatg acatgaaaaa aatcgttaaa tactcatctc
     4381 ttgctgccct aggacttgtt gctgcaggtg tgcttgcggc ttgctcaggg ggtgctaaga
     4441 aagaaggaga agcagctagc aagaaagaaa tcatcgttgc aaccaatgga tcaccaaggc
     4501 catttatcta tgaagaaaat ggcgaattga ctggttacga gattgaagtc gttcgcgcta
     4561 tctttaaaga ttctgacaaa tatgatgtca agtttgaaaa gacagaatgg tcaggtgtct
     4621 ttgctggtct tgacgctgac cgttacaata tggctgtcaa caatcttagc tacactaaag
     4681 aacgtgcgga gaaatacctc tatgccgcac caattgccca aaatcctaat gtccttgtcg
     4741 tgaagaaaga tgactctagt atcaagtctc tcgatgatat cggtggaaaa tcgacggaag
     4801 tcgttcaagc cactacatca gctaagcagt tagaagcata caatgctgaa cacacggaca
     4861 acccaactat ccttaactat actaaggcag acttccaaca aatcatggta cgtttgagcg
     4921 atggacaatt tgactacaag atttttgata aaatcggtgt tgaaacagtg atcaagaacc
     4981 aaggtttgga caacttgaaa gttatcgaac ttccaagcga ccaacaaccg tacgtttacc
     5041 cacttcttgc tcaaggtcaa gatgagttga aatcatttgt agacaaacgc atcaaagaac
     5101 tttataaaga tggaactctt gaaaaattgt ctaaacaatt cttcggagac acttatctac
     5161 cggcagaagc tgatattaaa taatttcttg aaatcatcca ttctgagtaa ggtgggtggt
     5221 ttctcagttt ttagggatat agttttaaac tatatatctg actatctaat aacaatttgt
     5281 gaaatcaaac aaattgtgag atactagtac ggtattattt ttaaggagaa agaatcatga
     5341 aaatcaaaaa atggcttggc ctagcagccc ttgctacagt cgcaggtttg gctcttgcag
     5401 cttgcggaaa ctcagaaaag aaagcagaca atgcaacaac tatcaaaatc gcaactgtta
     5461 accgtagcgg ttctgaagaa aaacgttggg acaaaatcca agaattggtt aaaaaagacg
     5521 gaattacctt ggaatttaca gagttcacag actactcaca accaaacaaa gcaactgctg
     5581 atggcgaagt agatttgaac gctttccaac attataactt cttgaacaac tggaacaaag
     5641 aaaacggaaa agaccttgta gcgattgcag atacttacat ctctccaatc cgcctttact
     5701 caggtttgaa tggaagtgcc aacaagtaca ctaaagtaga agacatccca gcaaacggag
     5761 aaatcgctgt accgaatgac gctacaaacg aaagccgtgc gctttatttg cttcaatcag
     5821 ctggcttgat taaattggat gtttctggaa ctgctcttgc aacagttgcc aacatcaaag
     5881 aaaatccaaa gaacttgaaa atcactgaat tggacgctag ccaaacagct cgttcattgt
     5941 catcagttga cgctgccgtt gtaaacaata ccttcgttac agaagcaaaa ttggactaca
     6001 agaaagcact tttcaaagaa caagctgatg aaaactcaaa acaatggtac aacatcattg
     6061 ttgcaaaaaa agattgggaa acatcaccta aggctgatgc tatcaagaaa gtaatcgcag
     6121 cttaccacac agatgacgtg aaaaaagtta tcgaagaatc atcagatggt ttggatcaac
     6181 cagtttggta ataagaaaca gggaggtggg agagaaaatt ccacctcttg cttttgtata
     6241 gagtatagat tgtaaagaag actattcgtt catagaaagg tagagagaat atggtttttc
     6301 ctagcgaaca agaacagatt gaaaaatttg aaaaggatca tgtagcccag cattattttg
     6361 aggttttgcg taccttgatt tctaagaaat cagtctttgc ccagcaggtt ggactcaagg
     6421 aagtcgcaaa ttatctgggt gagattttca agcgtgttgg agctgaagtg gagattgatg
     6481 agagctatac agcgcccttt gtcatggcac atttcaagag ttcgcgtcca gatgccaaga
     6541 ccttgatttt ctataaccac tatgacactg tgccagcgga tggggatcag gtctggacag
     6601 aggatccttt tacgctttcg gtccgcaatg gcttcatgta tgggcgtgga gttgatgacg
     6661 acaagggtca tatcacagct cgcttgagtg ctttgagaaa atatatgcag caccatgatg
     6721 atttacctgt caatatcagc tttatcatgg agggagcgga ggaatcggct tcaacagacc
     6781 tagataagta tttggaaaag catgcagaca aactccgtgg ggcggatttg ttggtctggg
     6841 aacaagggac caaaaatgcc ttggaacagc tggaaatttc tggtggcaat aaggggattg
     6901 tgacctttga tgccaaggta aaaagcgctg atgtggatat ccactcgagt tatggtggtg
     6961 ttgtggaatc agctccttgg tatctcctcc aagccttaca gtctcttcgt gctgcggatg
     7021 gccgtatctt ggttgaaggc ttgtacgaag aagtacaaga gcccaatgaa cgagaaatgg
     7081 ccttgctaga aacttatggt caacgaaacc cagaggaagt tagtcggatt tatggattgg
     7141 agttgcctct cttacaggag gagcggatgg cctttctaaa acgtttcttt ttcgagccag
     7201 cgcttaatat cgaaggaatc cagtctggtt atcaaggtca gggtgttaag actattttac
     7261 ctgcagaagc cagtgccaag ctagaggttc gtctggttcc gggcctagaa ccgcatgatg
     7321 ttctggaaaa aattcggaaa cagctagaca aaaatggctt tgataaggta gaattatact
     7381 ataccttggg agagatgagc tatcgaagcg atatgagcgc accagccatt ctcaatgtga
     7441 tcgagttggc caagaaattc tatccacagg gcgtttcagt cttgccgacg acagcgggga
     7501 caggacctat gcatacggtc tttgatgccc tagaggtacc aatggttgca ttcggtctag
     7561 gaaatgccaa tagccgagac cacggtggag atgaaaatgt gcgaatcgct gattattaca
     7621 cccatatcga attagtagag gagctgatta gaagctatga gtagagatat tatcaagtta
     7681 gatcagatcg atgtgacttt tcaccaaaag aagagaacca tcacagcggt taaggatgtg
     7741 accattcaca tccaagaagg ggatatctac ggaatcgttg gatattctgg agcaggaaaa
     7801 tcaacccttg tacgggtgat taatctcttg caaaaaccat ctgcagggaa aattaccatt
     7861 gacgacgatg tgatttttga cggcaaggtg accttgacgg cagagcagtt gcgtcgtaaa
     7921 cgtcaagata tcggaatgat tttccagcat tttaacctga tgagccaaaa gacagcagag
     7981 gagaatgtag cctttgccct taaacactct gaactcagca aggaagaaaa gaaggctaaa
     8041 gtagctaagt tgttggactt ggttggtttg gcagatcgtg ctgaaaacta cccttcacaa
     8101 ctatctggag ggcaaaaaca gcgtgtggca attgcgcgtg ccttggccaa tgatccaaaa
     8161 atcttgattt cagacgagtc aacttctgcc cttgatccga agacaaccaa gcagattttg
     8221 gccttgttgc aagatttgaa ccaaaaatta ggcttgactg ttgtcttgat tacgcatgaa
     8281 atgcagattg tcaaagacat tgccaaccgt gtggcggtta tgcaggatgg gcatttgatt
     8341 gaagagggta gtgtgcttga aatcttctca gaccctaaac aacctttgac tcaagacttt
     8401 atctcaacag ctacaggtat tgacgaagcc atggtcaaaa tcgagaagca agaaatcgtg
     8461 gaacacttgt ctgaaaacag tctcttggtg caactcaagt acgctggagc ttcaacagac
     8521 gagccacttt tgaatgaatt gtacaagcat taccaagtaa tggctaatat tctctatggg
     8581 aatatcgaaa ttctcgatgg tactcctgtt ggagaattgg tggtggtctt gtcaggtgaa
     8641 aaagcagcgt tggcaggtgc ccaagaagcc attcgtcaag caggtgtaca actaaaagta
     8701 ttgaagggag gacagtaaga tggaatcatt gattcaaacc tatttaccaa atgtctataa
     8761 aatgggttgg gctggtcagg caggctgggg aacggctatc tacttaactc tttatatgac
     8821 agttctttcc ttcattatcg gaggcttctt ggggctagtg gcaggtctct ttctcgtctt
     8881 gacagcgcca ggtggtgtct tggagaataa agtcgtattc tggattttag acaaaattac
     8941 ctcaattttt cgtgcggttc cctttatcat cctcttggca atcttgtcac cactttctca
     9001 cttgattgtt aaaacaagta tcgggccaaa tgcagccctt gtcccacttt cttttgcagt
     9061 ctttgccttc tttgcccgtc aggtgcaggt tgtcttggct gaattggatg gcggtgtcat
     9121 tgaggcggct caagcgagcg gagcgacttt ctgggacatc gtgggtgttt acctatcaga
     9181 aggtcttcca gatttgatcc gtgtgacgac tgtgaccttg atttcccttg ttggggaaac
     9241 agctatggcc ggtgcggttg gagctggtgg tatcggtaac gtagccatcg cttatggatt
     9301 taaccgctac aatcacgatg tgaccatctt ggcaaccatc gttatcattt tgattatctt
     9361 tgcaatccaa ttcttaggag atttcttgac taagaaattg agccataaat aaaaaagagc
     9421 cgtgtggctc tttttaactg atcagatttt ctgggcaaat tttttactca aggcttgtcc
     9481 aatcaaggca cccactaggg ctccgatgac aatacttgcg ataaatagaa ggacagttcc
     9541 agggtttgga gtgaccatga tacggtcgat atattcttgg gattttcctc ttgccagaag
     9601 agtagccata taggctttgg gcgcaatcca cataagcaag attggtcctg ttgtactaaa
     9661 ggcgaaaata atgaaagaaa ggaagttctt tgttttgtcc ttgtattttc ctaaatgagc
     9721 tacttcatct gctaggaggc cacagataat tccaggaagg aaggaaccag caccgtgttt
     9781 agttcccaag aaaaagaggg caatgacaag gccgatagtg gtaatggctc caaagcgcgg
     9841 aacttttgcg actaggatca tatagacgct accgccgaca agggcagtaa aggcaggcgc
     9901 ataaaacatg tttccagttt ggtcaaagag attgcccaaa aggacaccaa tccccatgca
     9961 gaggaagtaa agaactgcaa aaagcagtgt agttaagata gatttcttca tgaattgtct
    10021 cctgataatt ttttcacaat tctcattgta ccacggtttg gtgggattgt aaatggatac
    10081 tagaagtttt tgaaaacgct tgaaatatga tataatggtt tcatagttat ttttagggga
    10141 atatcatggg tagattttta gactttgtct ttaatcgttt ctttttaggg atgattgcga
    10201 cagccttctt ttggctatta actttagcag gagggattat ccttggtcta gcgccggcta
    10261 gtgccacctt gatgagctta tatgcagaac atggttatag ctttcgggaa tacagtttga
    10321 aggaggcttg gtctctttac aagcaaaatt ttgtctcaag caacctgatt ttctatagct
    10381 ttttaggtgt gggtctagtt ttgacctatg gtttgtatct attggtgcaa ttgcctcatc
    10441 agaccattgt tcatttgatt gcgacccttt tgaatgtcct agtagttgcc ctgatctttt
    10501 tggcttatac agtatcttta aaattacaag tttattttgc cttgtcctat cgaaatagtc
    10561 tcaaattatc cttgattggc atctttatga gtctagcagc tgtggccaag gttctccttg
    10621 ggactgtgct acttgtagca attggttact atatgcctgc cctgctattt tttgtaggaa
    10681 ttgggatgtg gcatttcttt atcagtgata tgttggaacc tgtctatgaa atcatccatg
    10741 aaaaattggc gacaaaatag aatgaagcag ttttggctac atacgcttct aagaacctat
    10801 agttcagtga tgatcattat cattgcgagt tttgcaatct tactctctta cgctgactgg
    10861 gattcacgtg aaaaggaagc ccagagagta gcccagcgtg taactgctag aacagtgagt
    10921 gaaattgaat attaccatag agagtcaacc cagatagctc aggctttagt tgaaaatcaa
    10981 gctcgtattg agggaatcta taaatacttt agccttagca tgccagacta tttttactgg
    11041 caattagagc ggaaagcttc gccttatata tcagtctctc tgtatgaaaa tgttgatgac
    11101 ctctatgttc gaaatgattt tgtaactggg gtggccattg cttttcaaga ttacaaggaa
    11161 gtctatgttt ctactaaaga caaacgtagt ggagaaaaaa tcagggctga ggatttcaaa
    11221 ccagcaggaa atagttttgc cattccggtg tcagatccag tgtcagatca agatttagga
    11281 gtgatttaca tctccttgga tcctgctgtt ttataccatg ccattgataa tactagaggt
    11341 catactccga tggcagtaac agtgacctca ccttttgata cggagatttt tcatattggt
    11401 gagacagttg atagggagag tgaaaattgg ctagttggct taacttctca tggatatcag
    11461 gttcaggtgg cagttcctaa aaactttgtt ttacaaggaa cagtgactag ctctgctttg
    11521 attgtgggtt tgagccttct ctttattgtc attctttatc tgactttgag gcagactttt
    11581 gctaattacc aaaagcaggt agtggattta gtagaatcca ttcaagtcat tgctcaaggc
    11641 gaagaggggc gtcggattga catttccgag aaagatcagg aattactcct aatcgcggag
    11701 acgaccaatg atatgttgga tcgattggaa aagaatatcc atgatattta ccagttagag
    11761 cttagtcaaa aagatgccaa tatgcgagcc ttgcaggcgc aaatcaatcc tcattttatg
    11821 tataatacgc tggagttctt gcgcatgtat gcagttatgc agagtcaaga tgagttggca
    11881 gatatcattt atgaattcag tagtctcttg cgtaacaata tttccgacga aagagagacc
    11941 ctcctcaaac aggaattaga attttgccgt aaatacagct atctctgcat ggttcgctat
    12001 cccaagtcca ttgcctatgg tttcaagata gatccagagt tagagaatat gaagattccc
    12061 aagtttacct tgcaaccgct ggtagaaaac tatttcgcgc atggtgttga ccacaggcgg
    12121 acagataatg tgattagcat caaggctctt aaacaggatg gttttgtgga aattttggtg
    12181 gtcgataatg gtagaggaat gtcggctgaa aagttggcaa atatccgaga aaaattaagt
    12241 cagagatatt ttgaacacca agccagctac agtgatcaaa ggcagtctat cgggattgtc
    12301 aatgtacacg agcgttttgt gctctatttt ggagaccgct atgccattac tatagagtct
    12361 gcagagcaag ccggtgttca gtatcgtatt acaattcaag atgagtagaa agggagaaaa
    12421 tgtataaagt attattagta gatgatgagt acatggtgac agaaggtctg aagcgtttga
    12481 ttccctttga taagtgggat atggaggttg tcgcaacagc cagtcatgcc gatgaagctc
    12541 tagaatatgt tcaggaaaat cctgtcgatg tcatcatttc cgatgtcaat atgccagaca
    12601 aaacagggct tgatatgatt cgggagatga aagagatctt accagatgct gcctatatcc
    12661 tgctctcagg ttatcaggag tttgattatg taaaaagagc aatgaacctt agtgtggtgg
    12721 actatttggt caagcctgtt gataaggtag agctgggaaa tctgctggag aagattgcag
    12781 gtcagctcgg cgagagaggg aagaaaagtc agactcttag tcaagaatta gacgaggctg
    12841 gatttgttag ttatttaggg gataaggaga attggtggat aggtctatcc aaggaaaaac
    12901 aaggttcctt caccattccc tactatgtct tgggccaaga ctggcagatt ttcatttctg
    12961 gccaacctct agatggttta gtcgttacac cttttgaagc tccttatcaa gaacactttg
    13021 aacgctggaa gctgaatgct gagaaaaccc tcttttacgg ttctgtaaat ttgcagcagt
    13081 ctgagagtct ctttgcctat tacgaaccga tttatagggt tatcattcag ggaaatctca
    13141 atcaaatcgt agaagagtta aatctcttgg agaaggtagt tcttgaaaat acgccgcgtg
    13201 ttccgattac taaacagctt tttattcagt ttgtcatgga tgttttccat ttatttgaac
    13261 atctcaaagc tgatgacctg acagacatcg tcaaaaccat tcatgctatt caatccttcg
    13321 atgaattggt ttcttatatc aaggaaactc tgatcagctt tttcggtcaa taccgtatga
    13381 atgaaaatgt ggtcagtgtg ctggaagtca ttggtcgtga ttaccaaaaa gagctttccc
    13441 tcaaggatat cagtaaggct ctctttatca atcctgtcta tctagggcag ttgattaagc
    13501 gtgaaaccga ttcgaccttt gcagagttac taaacaaaca acgtattaag gctgcccaac
    13561 aacttttgct ttcaactagt gacagcatcg aagatatttg ttatgctgtt ggttacagta
    13621 accttggata tttctataaa gttttccgaa aattgtgcgg aaaatcgcca aaagcctacc
    13681 gaaaacaggt agaaactata ctataaaatt tgtattcctt tacaaaaggt gctataatat
    13741 tatcaggagg ttctatcatg aaaaagaaac caatttatct atgggtcttg ctaatcttgt
    13801 ctgcccttat ttcagttccg tctctgtttg gaattgtgag tcccttgcct agtaaggaag
    13861 cccttcgtgc tgctcagaaa caagttgcag gggtcaatgc tcagcaatta gaagaccagc
    13921 ttaattatac ctatagagta gcagaagcat ctcattctat ttttaatgtt gctttgattg
    13981 tgctatctac tattttagtg gtcgtagcga ttgtcttcct tgttcgtaaa aatttgcaat
    14041 atgcaaacta tacttacgtt ggctatgttt tgttagctat tattggttcg atttatggct
    14101 atgttggttt acaagacgct gtgcagttgg ttcaagatga gagcatgcgt ttgacagtga
    14161 gtattggttc aaaagctgtt agcattttct atatcgtcat caatgttctc ttcctagccc
    14221 ttgtcttcta taagatgtgg cgacaacaga aagccttggc agaagaagag gaaacagaag
    14281 agcttgccta agtattgaca aaaaagaact atcaagatac aatcttggta gttgtttttt
    14341 gattatagat aaaatcatgg aggtacatat gaagacaatt tctttagttt atattagttt
    14401 gagtggcaac actgaaagtt ttgtgacgcg cttgaaagac tatctcttgt cccagtacaa
    14461 agggattgag gttcaaaaga ttcatatcaa ggatttagtc aaggaaggca aaaatttcta
    14521 tgaaatggac catccctatg tcgctttttt gccgacctat ctcgaaggtg ggaatggcgt
    14581 ggataacgga gatgttgaga ttttgacgac accggtggga gattttattg cctatggtaa
    14641 caatgctagt aagtgttttg gtgtggttgg gtcaggaaat cgtaacttta ataaccaata
    14701 ctgcctaaca gccaagcaat acagtcaacg ctttggcttt cctgtattgg ctgactttga
    14761 aatgcgaggc atgctggaag atatcaaaca tgtcgcagct attatcgcag atttgtatga
    14821 gttggaaaag gagaattaat actcaatgaa aatcaaagag caaactagga agctagtcgc
    14881 aggttgctca aagcacagct ttgaggttgc agatagagct gacgtggttt gaagagattc
    14941 tcgaatagta taaagttctt ataagaggtg gttgaagttg ttcaactgtt ttttgagtat
    15001 aaacagtctt taagaacgta aaaaagcata agttcaggtc ttcaaaacct tgttcttatg
    15061 ctttttatca tagaaatatt tgctgaattt tctcttgaaa tgaaacctta tcttcatctc
    15121 gcgcttgtcc cttaccctgc ttttccgatt gcgagtgcgt agataaagaa gatggcgaag
    15181 ccaaagagga aaatcaatcc cgcaatggca aggtgtttga gccaagaagg aagatttttg
    15241 ttttcacgcg ttaccaaggc gtaattcaaa agagcaaaga aaggtgttgt caggaaagag
    15301 ccaatcatgg caaagcggag catggttgaa acctgaccag cgaagaactt gataatgacg
    15361 ataccgatga tagcagtgat ggtcatccag atgttcaaag atttacgatt gtcctctttt
    15421 tgactgatta gcagtcggag agattcctga ttaacgcgag aatagccatc gataacagtt
    15481 ataactgttc caaagataca gaggaaggca ataaaggtaa tcaagtaacg ggaccattcg
    15541 ccaagaacag aggcatacat gcccacgaat tgagagatgt atttggctga agcagcttca
    15601 accgcctgcc ctgtaggata ctgaatcagt gctcccagtg ccacaaagaa gacggctagg
    15661 atagctgttc caatataacc agtgttaaag tcaaacacag cgtcttctgt gttaaagttg
    15721 acggtctttc tcttttcagc tgaccaaagt gaattgatgg ctgaaatttc aataggagcc
    15781 ggcatccatc ctaggaggga gacgatgaag ggcagagctg ccatttgcca aggtgtcttc
    15841 tcgacaaaat cagaactgta ttctggatgc ttgaccgccg caatgataac tgcaagaaca
    15901 gtcgcaatgg ttaaggcaga cataatccat ttgaccatgc cgtctaaaag tttgtagcct
    15961 ccaaagagta gcatagccca aatgattgca acgagaatga gggaccactg agtaatgcta
    16021 agtccaatca ttgggaaggc actggcgatg atagctgagc acagaatggc aacaccagcc
    16081 gtgttgacca tagccgaaaa gacattgagg ataaagaaaa tccagagata gagttttcct
    16141 ttttcggcat aaccttcaac caaagtcttt ccagtatcag ctgtgtattc agcaccaaaa
    16201 cggaaaaatg gatatttaaa gacattggct aagatgacca agagaagtag agaccaaccg
    16261 taagaaccgc cagcttgagt tgaggataca atgtgggaac ctccaacagc ggcagttgcc
    16321 attaggattc caggtcccat tgcttttagc ttgcttgccc aggttgattg atttaaggaa
    16381 atagcttgcg acatgataaa tactcctttt tgaattttca gaataatctg tatatgtaat
    16441 ctatattcta caaaaaattt tggaaaaatg caagagtatt ttgaaaaaag atagaaaatt
    16501 tacaaagaaa atctgaaata actgttatga tatagcagat tgaaactaga atagtacact
    16561 tttgcttcta aaacattgtt agaaatcgat ttgactgtcc tgattgattt accctgttct
    16621 tatttcattt cactatagta aggtgcagca ggataaagca aaaccgagaa gtttctttct
    16681 cggttttgct tattatgagg ttcctatttt ctatgctcca agagttgatt gatgtgatct
    16741 acttttttag cctctctttt atagagaata gcccagatga tgagatagac aatcgcaaac
    16801 tcgataatga gctggaggta gaaaatccag tggaagggga accaaccagc aagagttgct
    16861 agtgggacaa agccagccag cataaggaag aaatgagtca gagtggcacg aagcatgctc
    16921 cagtcacggc tgaataagcg gttgccaaag ttgaagagca taccgatggc tgcccagata
    16981 agtgtgcagt agagcaagac cagggcaccg tgaacctgat gctgatccat cacttggccg
    17041 atgagagagt agggatttag tggtgcgtag gtatttggtg cataaatgag tgaaaagagg
    17101 atggagagga tgaggccgat aagaacaccg gcagctgcat cgtgaaatac ttgttttttc
    17161 atagttctaa tttctccttg atggttttta gataacggcg tgaagagtag gtgaagcttt
    17221 cgtttttcaa gaaaatttct accagaccgt ttggcgtgag cttgaggtga gagatggaat
    17281 cgatattgat gatttctgat tgggaaattt ggataaaatt ggttggcaag agtttaagaa
    17341 cctgatagag tcgcaaatca atgctgtagg tctgactcgc ggtttctgct agaaccttcc
    17401 gattctcgat atagaagcgc tgaatcttgc caatctcaac tagatagacc tgatcatcga
    17461 tttttccttt gattttttct ctttggtcca gattttctgc gaactcgatg actttctgga
    17521 ctttttcggt ttcttgaggt gcttggacaa tcagcttttc ctcctcgtaa gtctcactaa
    17581 tctgtagttc tactttcata aatttctctc cttgtttttc atacaaaatt aatctcactt
    17641 cttgtacacc tttattaata ctcttcaaaa atctcttcaa accacgtcag cgtcgtcttg
    17701 ccgtaggata gttgttgact ttgtcagttt tatctacaac ctcaaaacag tgttttgagc
    17761 tgtctgcgtc tagctttcta gtttgctctt tgatttttat tgagtatacc actattttac
    17821 tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg gtggagtttt
    17881 tctgttcttt ctgaaatatg gtataatagc actaattaat ttctaggaaa atagatacag
    17941 aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca aaccaaatcg
    18001 cagctgggga ggtcattgaa cgtcctgcca gtgtggttaa agagttggta gaaaatgcca
    18061 ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc aagaaggttc
    18121 aaatcacgga taacggtcat ggaattgccc acgatgaggt ggagttggcc ctgcgtcgcc
    18181 atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg cttggttttc
    18241 gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta acggcggtgg
    18301 atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag gaagtcatcc
    18361 cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc aacacgcctg
    18421 cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt gatattgtca
    18481 accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat ggcaaggaaa
    18541 tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt tacggtttgg
    18601 tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa atttcaggtt
    18661 ttgtgtcttt acctgagttg actcgggcta accgcaatta tatcagcctc ttcatcaatg
    18721 gccgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc ggaagcaagc
    18781 ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct tatctagcgg
    18841 atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa gaactgatga
    18901 ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt ccagatgcct
    18961 tggaaaatct tgccaaatcg accgtgcgca atcgtgagaa ggtggagcaa actattctcc
    19021 cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct agtcaaactg
    19081 aagtagctga ttatcaggta gaattgactg atgaagggca ggatttaacc ctgtttgcca
    19141 aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag agaaagcctg
    19201 ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat aaggcttatg
    19261 acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc ggacaaatgc
    19321 acgggactta tctctttgcc caagggcgag atggacttta catcatagat cagcacgctg
    19381 ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt gaccagagcc
    19441 agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc ctgcgtctca
    19501 aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac ggagaaaatc
    19561 aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa tcaggcatct
    19621 atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa taccgagcag
    19681 agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt attgatgatc
    19741 attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat aactgtcctc
    19801 acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg ttccgacgta
    19861 ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat aaaaaagtct
    19921 gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa ccttgatttt
    19981 atgcgtttta tcatagaaat atttacttca tgttttccta attcttttcg aaactctttt
    20041 taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat tttgccagtt
    20101 ttgtctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta gtttgctcta
    20161 tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt ctaaaagtag
    20221 agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc tccttgtgca
    20281 cactcagaac ccttatttcc tgctttagtg ccagctcgtt ctatggcttg ttcaattgta
    20341 tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat ttgggcgatt
    20401 cccttagata cctcgctaca tacataatca taatgacttg tattccctct aatgacagct
    20461 cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc aatcagtggt
    20521 atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac attctctctt
    20581 ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt aaatctcgct
    20641 acaacaatac ctattttaat attgtttgct actaaattac cttcataagt gttcatttat
    20701 ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa ataaaaacta
    20761 tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat tccatatttt
    20821 tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg aagtcccaga
    20881 tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa gcctaatgca
    20941 agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt taatttattg
    21001 ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga accattctca
    21061 acaattattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa agagcctaaa
    21121 acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc atcctctatg
    21181 tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata gctaattgct
    21241 ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac cagctgatca
    21301 tatgcttttc tatattcttg taattctttg atggtaatta gtggaatgtt gtgtttcttc
    21361 gagaactgaa ttaaatcatc tattctcatc attttgccat catgattcat tatttcacaa
    21421 cataggccac actcttttag tccagctaat tttaataaat caacagttgc ttctgtgtgt
    21481 ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg tcctggcctg
    21541 cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag tcctctctcc
    21601 tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa agcagtctta
    21661 tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc taaactttcg
    21721 ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac attttctgtt
    21781 gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt gtcgtctata
    21841 acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt tcgatattcc
    21901 attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct tcgatatttc
    21961 tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat cattttcaag
    22021 atttactgta ctcccgactt gtttactctt aagaatggtt tgtttcaagg tatgagggat
    22081 aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa tgccgtcaat
    22141 tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt tgatttgata
    22201 ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat caatgtgtcc
    22261 tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta gattcacctc
    22321 acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca ttacatcaac
    22381 tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta ctgctatact
    22441 atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt tacaattacg
    22501 agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg tgaacatgga
    22561 taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc ataaggtttc
    22621 aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa cttggcactg
    22681 cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg ttgttccaaa
    22741 gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg catgtttcct
    22801 agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat ggaaagtatt
    22861 tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga agtggcaatg
    22921 taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt tcgtaaatgt
    22981 gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt cagcaaagga
    23041 tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg tcgtaactga
    23101 tgcacatgct ttcttgcctc ttcttcagta atccatttgg attgatttgt tttagtggct
    23161 atttttccat ccattgtcat tgcatatttc ataaaaacat agggtacatg ctgggtaata
    23221 tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc aacagtaact
    23281 tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg attacagtct
    23341 aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat acaaggaggt
    23401 gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc gacaggggat
    23461 tctctacagt ttttaagagc atttctctca gcatgtgagc caccaaaaaa ctcatgataa
    23521 ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg attgggattg
    23581 acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt tgaatcgctc
    23641 atctcactac ctccaaaaaa atataccttg aataggagac tactcaaggc atacaaaaga
    23701 aaacttatgc gattaacaaa aatgctctga aatgacaagt aatcatttca gagcacgcaa
    23761 aaagcacaaa tatactttta tcttctttca tccagactat actgtcggct ttggaatttc
    23821 accaaatcat gcctttcggc tcgtgggcta taccaccggt agggaattgc accctgccct
    23881 gaagatagtt attcaattac agatgattat agtacttaat tttgaatatg tcaacagata
    23941 aataccgatt gtttttgata tactgtattt gtgataatcg attctcgctc ctcggataaa
    24001 gaaaatatga tatactagat aaacgaaata agagagaagg aacactatgt acgcatattt
    24061 aaaaggaatc attaccaaaa ttactgccaa atacattgtt cttgaaacca atggtattgg
    24121 ttatatcctg catgtggcca atccttatgc ctattcaggt caggttaatc aggaggctca
    24181 gatttatgtg catcaggttg tgcgtgagga cgcccatttg ctttatggat ttcgctcaga
    24241 ggatgagaaa aagctctttc ttagtctgat ttcggtctct gggattggtc ctgtatcagc
    24301 tcttgctatt atcgctgctg atgacaatgc tggcttggtt caagccattg aaaccaagaa
    24361 catcacctac ttgaccaagt tccctaaaat tggcaagaaa acagcccagc agatggtgct
    24421 ggacttggaa ggcaaggtag tagttgcagg agatgacctt cctgccaaga tcgcagtgca
    24481 agcaagtgct gaaaaccaag aattggaaga agctatggaa gccatgttgg ctctgggcta
    24541 caaggcaaca gagctcaaga aaatcaagaa attctttgaa ggaacgacag atacagctga
    24601 gaactatatc aagtcggccc ttaaaatgtt ggtcaaatag gagcagagaa tgacaaaacg
    24661 ttgttcgtgg gtcaagatga ccaacccact ctacatcgcc tatcatgatg aggagtgggg
    24721 ccagcccctc catgatgacc aagcgttgtt tgagttgttg tgtatggaaa cctatcaggc
    24781 aggcctgtct tgggaaacgg tactcaacaa acgccaagct ttccgagaag cctttcatag
    24841 ctatcaaatt cactcagtcg cagagatgac tgacactgaa ttggaagcca tgctggagaa
    24901 tccagctatc attcgaaata gagccaagat ttttgctaca cgcgctaacg cccaagcctt
    24961 tctacagtta caggcagagt acggctcttt tgatgcctat ctttggtctt ttgttgaggg
    25021 gaaaactgtc gttaacgatg ttcctgatta tcgccaagcc ccagctaaaa cacccttatc
    25081 tgagaaatta gccaaagatc tcaaaaaacg agacttcaag ttcacaggcc cagtcgccgt
    25141 attgtctttt ctacaggctg cagggctagt tgatgaccac gagaatgatt gtgagtggaa
    25201 aggtcttaaa tgatgtctaa caaaaataag ggaattctga tttttgcgat tctctataca
    25261 gtcctctttg tgtttgatgg cgttaaattg ctggcttctt taatgccatc tgccattgca
    25321 aattatcttg tttatgtagt tttagcttta tatggctcct tcttgttcaa ggatagattg
    25381 atccaacaat ggaaggagat tagaaagact aaaagaaaat tcttctttgg agtcttaaca
    25441 ggatggctct ttctcattct gatgactgtt gtctttgaat ttgtatcaga gatgttgaag
    25501 cagtttgtgg gactagatgg acaaggtcta aatcagtcta atattcaaag tacctttcaa
    25561 gaacaaccac tactgatagc tgtttttgct tgtgtcattg gacctctggt agaagaatta
    25621 tttttccgtc aggtcttatt gcattacttg caggaacggt tgtcaggttt actaagcatt
    25681 attctggtag gacttgtttt tgctctgact catatgcaca gtttggctct atcagagtgg
    25741 attggtgcag ttggttactt aggtggaggc cttgcctttt ctattattta tgtgaaagaa
    25801 aaagagaata tctactatcc cctacttgtt cacatgttaa gcaacagcct ctccttaatc
    25861 attttagcta tcagtatagt aaaatgaaat gagaacagga caaatcgatt tctaacaatg
    25921 ttttagaagt agaggtgtac tattctagtt tcaatatact gtaatatgtg atgaaaatgc
    25981 cagtaatgat accgagaaaa aagctgagaa acttttccca gctttatttg ttatagtcaa
    26041 agagaatgac ttgttcctgt gcatctacat gagcatggac cccaaagggt acaattgctc
    26101 ttggagttgc gtggccgaca ttcagattat agacaatcgg gatattgctg tcaatgatat
    26161 ccaatagtgc ctctttatag tcgtcatgga aagtttcatc cataggtttt ccgaccaaga
    26221 gtccattgat gaccgcgaat atgccagtgt cctttaaagt tagcaacatc tttttgaagt
    26281 cttctggctt aggcttttct tcgcttgttt cgagcaagag gattttccct tcccagtctg
    26341 acaagtcagg gaaaagtttg tatttttggc agagttccgt gctatctgcg tatcgagagt
    26401 tgtcaaagat atcgtagagg gattcgaggc aaccaccgag gattttcccc tcgaactgag
    26461 cacttccttg caacaagtca aaacctgtat ttgtatgact gacacgaggt gttcccaggg
    26521 ccgtgggact aaaatcagtt cgttcctcat accaaacgtc actagggcgg atttctgaaa
    26581 ttcttcccgt ctcaatcaat tctttaaagt agtgaaggct ataggctagc atttctttgt
    26641 ctaattcaca aatgtctgct aaaaaggatt gaccataaaa agtcttgatt cctaatttat
    26701 gcaacatgag gtggttcatg gttgtatccg agaagccaag aaaaattttt tgtttgataa
    26761 ccttttggag ttggtcattt tcaaaaagat aaggtagcaa gcgataggta tcgtctccac
    26821 cgatggcaca taggatcatg tcgatgctat catcagaaaa ggcatgaatc aaatcctctg
    26881 cacgagcttc aggatggtcc ttgataaagt ctaatccttt taacgaatgg ggcaaaaaga
    26941 tgggattgag tcccagatcc ttgagacgtt ggatacccaa gtccacttcg tgtttgacaa
    27001 aatcctctcc gataatgcca ctagataaac taacaatacc aatagtagaa accatatctc
    27061 atcctcctag aaatagattg agcctatttt atcacaaaat ataagagaaa gctatgtggg
    27121 atttcagaag aatactttta atactcttcg aaaatctctt caaaccacgt cagttttatc
    27181 tgcaacttca aagctgtgct ttgagcaacc tgcagctagc ttcctagttt gctctttgat
    27241 tttcattgag tacaactcaa aaaagtaagt gaaaaagcaa ccgcacctgc agttgctttt
    27301 atcgttttct tattcttgat agcgtgttgg tcctgcactt gcactacgga tattcaagcg
    27361 tttcttgaga tagaagcgaa gggctaggag ggctgctcca ataatagcta gtggcaatgg
    27421 atccagtact gggttaaggc tagctggtag gaagcttgtt gcaaagaaga caagcaacca
    27481 aaggaacata gaagctagga taactagtac agatttccag aaaggtggac gttgactgcg
    27541 atccatatct ggtccatagt attggtaaac aaagtagtac atcaagtaga aggcaaatcc
    27601 accaaccagt ccaactaata gaagagtaat caatccatag ccgaaagctt gatctgccgc
    27661 aaagaaggtt gtgagggcgc tgacaagggc aaagaggcta gtgatgaaaa gagctgagtc
    27721 cataatcatc agttttggat catcattttc ttttggatgc tctttttcgt actgctcttt
    27781 gacagtgaag ctatgagccc aatgagttgg tgcgccgtat agggaacggg cagttgtacc
    27841 tttagattgc tcctcaagga tttggggaat gacttcctca aaaatagtct ggatttcagc
    27901 gtctgttttc ccatctttga tgaattgttg ggtagcaatg tggacaaact cttggttttt
    27961 cttagttaat ttttgtagat caatttgaga cataggaact cctcttagaa ccatttttta
    28021 tggatgagat agagagtgag cgagacactc atagcaaagg cgataaagac gattaaccag
    28081 aaggcatttg gctctccgtt taggggaatt tcattatcct taaagttcat cccgtaggca
    28141 gaaaagacca tggttgggat ggacatgacg atggtcacaa gggccaaggt tttcatgatg
    28201 ttgttctggt tgttagaaat gatagaggca aaggtctctg tcatagaatg caagacgttt
    28261 ccataaatat ctgccatctc gatggcctgt tgggtttcaa tcagggtgtc ttcaagcagg
    28321 tcttcgtcct caaggtattt cttgatattg ctggttgaac tggtcaattt cttaatcacg
    28381 cgctcatttg ttttgaggga ggccttgaaa tagacgatag ttttttccaa ttccatgagc
    28441 tcaatcaatt cttcattacg agttgattga tgcagttgac tttcgatttg ttcactcttg
    28501 cggtcgattg aacgaagggc tgttaggtaa agctctgcat tgcgataaag aatttgaaag
    28561 ataaaacgtg aacgcatgaa ggtatagaaa ttacgcaatc gacggttgat aaagacatca
    28621 aggacaggta gtggttccaa acacgtagtg ataatggttt cctcagtgat gataatacca
    28681 agcgggatgg ttacgtagta ggtgcggtta tttctttcct ccgtgaccgg cacgtctacg
    28741 ataatcaggg tatactcgtc ttcaatggta atacgagaca tttcttccgc atcgagcggt
    28801 gctcgaaggt cggcaatatc aatatcgaag gtgttggcga tttcgagtga ttcattttga
    28861 gtcggattga cgagattgat ccaagtaccc ggttcaagcg tatcgatctc tttaaattca
    28921 gttgttgtag agagaaaaac ttgtttcata tcccttatcc tttctcattt ttcagatttt
    28981 ttcacactgt actattatac tacaaaatcg gccttttggg taatagaatc tcactttttt
    29041 tggtataatg gtaagcaata atggactaga aagaacaaag atgcaagata aaattgtcat
    29101 tcatggggcg cgtgcccata atttaaaaaa tattgatgtg gagattccgc gagacaagtt
    29161 ggttgtcgtg actggcttgt caggttcagg gaagtccagt ctggcttttg ataccctcta
    29221 tgcggaggga caacgtcgct atgtagagag tttgtccgcc tacgctcgtc agttcttggg
    29281 aaatatggaa aaaccagatg tagatgccat tgatggtctc agcccagcta tttccatcga
    29341 ccagaaaacg actagtaaaa atcctcgctc gacggtggga acgacgactg aaatcaatga
    29401 ctatctgcgt ctcctctacg cacgtgtggg gacgccttac tgtatcaacg gacatggagc
    29461 tatcaatgct tcttcggtgg agcaaatcgt tgataaggtt ttggagttac ctgaacgcca
    29521 gcgcttgcag atcttggctc ctgtcatccg caagaaaaaa ggccaacata agagtgttat
    29581 cgagaaggtt cagaaagacg ggtatgttcg tgttcgtgtg gatggggaag tctatgatgt
    29641 gaccgaagtg ccagagttgt ctaagagcaa gcaacacaat atcgatgtcg tggttgaccg
    29701 tattgttatc aaggagggca ttcgtagtcg tctctttgat tccattgagg ctgcccttcg
    29761 tattgcagaa ggttatgtca ttatcgacac catggacgat tcggagttgc tcttctctga
    29821 gcattatgcc tgtccagttt gtggttttac tgtcccagag ttagaacctc gtctcttctc
    29881 tttcaatgct ccttttggct cttgtagtga gtgtgacggc ttggggatca agctggaggt
    29941 ggatactgat ttggtagtgc cagatgccag caaaacctta cgtgagggag cgctagcacc
    30001 ttggaatcct atctcatcca actactatcc aaacatgtta gagcaggcca tgaaagtctt
    30061 tggagtggct atggataagc cttttgagga cctgtcagaa gaagataaga acttgattct
    30121 ctatgggtca gatggtaagg aattccattt ccactatgag aatgaatttg gtggcgtgcg
    30181 cgatatcgac attccgtttg agggagttat caataatatc aaacgtcgtt accatgaaac
    30241 caatagcgat tacactcgca ctcagatgcg tctctacatg aatgagctga cctgcggaac
    30301 ctgtcaaggc tatcgtctca atgaccaggt cttgtctgtc cgtgtgggcg gccagcaagg
    30361 gccacatatt ggagaaatct cagacctgtc tatcgctgac cacttggact tggtgagcca
    30421 gttaactttg tctgaaaatg aagccatcat tgctcgtccc attctcaagg aaatcaagga
    30481 tcgtttgacc ttccttaata atgtgggtct taactatcta accctgtcac gttcagcagg
    30541 aaccctttca ggtggggaaa gtcagcgcat tcgtttggca acccagattg gttccaacct
    30601 atcaggcgtc ctctatatcc tagacgagcc gtcaatcggt cttcaccaga gggacaatga
    30661 ccgcctgatt gccagtctga aaaagatgcg tgacttgggc aatactctta tcgtggtgga
    30721 acacgacgaa gataccatgc gtgaagctga ttatctgatt gacgttggtc ctggtgccgg
    30781 tgtttttggt ggtgagattg ttgcagcagg tacacctaag caagtggctc gcaacagcaa
    30841 gtctatcaca ggtcagtact tgtcaggcaa acgtgtcatc ccagtaccag aagagcgccg
    30901 tgtcggaaat ggtcgtttta ttgaagtgac aggagcgcgt gagaacaact tgcaaaatgt
    30961 cacggctcgc tttccactag gaaaatttat cgcagtgaca ggtgtgtcgg gttcagggaa
    31021 atcgactcta atcaacagca ttctcaaaaa agccattgcc cagaagctca accgtaattc
    31081 agacaaacct ggtaagttta agactattac agggattgag catgtcgacc gtttgattga
    31141 tattgaccag agccctatcg gacggacgcc gaggtctaac ccagctacct atacaggagt
    31201 ttttgacgat atacgtgacc tttttgctca gacaaatgaa gccaagattc gaggctacaa
    31261 gaaggggcgc ttcagtttca acgtcaaggg aggtcgctgt gaagcttgct caggtgacgg
    31321 gattatcaag attgagatgc acttcttgcc agatgtttat gtggcttgtg aagtttgcca
    31381 cggaacccgc tataacagtg aaaccctaga agttcactac aaggaaaaga atatttcgca
    31441 ggtcttggat atgacggtca acgatgcggt agaatttttc caacacattc cgaaaattca
    31501 acgcaaactc cagaccatca aggatgtagg gctaggctat gtgaccttgg gacagccagc
    31561 taccaccctt tctgggggag aagcccaacg tatgaagtta gctagcgaac tccacaaacg
    31621 ctcgacagga aaatctttct acattctgga tgagccgacg acagggcttc atacagagga
    31681 cattgctcgc ctgctcaagg ttttagctcg ctttgtagac gatggcaata cagtcctcgt
    31741 catcgagcac aatctggatg ttatcaagac ggcagaccat atcattgact tgggacctga
    31801 gggcggtgtc ggtggtggaa ccatcatcgt aacaggaact ccagaagaag tagctgccaa
    31861 cgaagccagc tatacaggac actatttgaa aggaaagtta catcatgaat aaacgcgtac
    31921 aagcatttct agctaaaatg caagaaaaag aactagatgg tatcatcatc aacaatctta
    31981 aaaacgtcta ttatttgact ggtttttggg gctcaaacgg aacagtcttt atcagtcgtg
    32041 accgtcaggt cttagtgaca gactctcgct atatcatcgc agctaagcaa gaaaccagtg
    32101 gttttgagat tgtggctgat cgtgatgaat tggctgtcat tgcaggaatt gttaaggaca
    32161 tgggcttgac tcgtatcggt tttgaagatg agatttcagt gtcttattac caccgtatgc
    32221 aggcagcttt tgcaggtttg aacttgcttc cacaaactca gtttgtggaa ggtcttcgta
    32281 tgattaagga tgaggcagag attgcagcga ttcgcaaggc ttgttctatc tcagaccaag
    32341 ctttccgcga tgcgcttgac tttatcaaac caggaaaaac tgaaattgag attgccaact
    32401 tccttgactt ccgcatgcgt gagttgggag catctggctt atcttttgat acgatcctag
    32461 ctagcggtat caattcttct aaaccccatg cccatccaat gcacaaacca gtggagttgg
    32521 gagaagccat taccatggac ttcggctgtc tctatgacca ctatgtcagt gatatgaccc
    32581 ggactatcta tctagggcat gttagcgatg agcaggcaga gatttacaat acggttctaa
    32641 aagctaacca agccttgatt gaccaagcta aggcaggctt aggtttccgt gactttgaca
    32701 aaatccctcg tgatattatc attgaggcag gttatggcga ctactttact cacggcattg
    32761 gccacggtat tggtctggat atccatgagg aaccctactt tagccagact tctacagaaa
    32821 ctattaagac aggtatggcc ttgaccgatg aaccaggtat ctatatcgaa ggcaaatatg
    32881 gcgttcgtat cgaggatgat atcctgatta cagagacagg ttgtgaatta ttgaccctag
    32941 ctccaaaaga gttgatagtc atttagttgt ttgtcaagaa aaaagtacga aaatgacgaa
    33001 aaaagtcaaa aaaaattaaa aataggtcgc aagtcggatg ttttttatgg tataatagac
    33061 taaactgata gtaacatgta gcgaaagggg taggtacatg attaaaattt atacagtctc
    33121 aagttgtact agctgtaaaa aagcaaaaac ctggctcaat gcccaccagt taagttataa
    33181 agaacaaaac cttggtaaag aaggaattac gagagaagaa ttactggata ttctaaccaa
    33241 aacagataac ggaatagcca gcatcgtttc gtctaaaaat cgctatgcca aagcccttgg
    33301 agtggatatt gaagatttga gtgtcaatga agttctcaat ctgattatgg aaacaccgag
    33361 aattttaaag agcccaatcc ttgtagatga aaaacgcctg caagttggct acaaggaaga
    33421 cgatattcgt gccttcctac cacgctctgt ccgtaatgta gaaaatgcag aagcacgttt
    33481 gcgtgcagct ctataaacat caaggctggg agcacttccc agtcttattc tattttaatt
    33541 tcaaaaagaa agaagaaaga aatgaaaaaa atagttcttg ttagtctagc tttccttttt
    33601 gtcctggttg gttgcggaca gaaaaaagaa actggaccag ctacaaaaac agaaaaagat
    33661 acgcttcagt cggcattgcc agttattgaa aatgctgaga agaatacagt tgtaactaag
    33721 actttggtct tgcccaagtc agatgatggt agccagcaga cacaaacaat tacttacaaa
    33781 gacaagactt ttttgagtct aactatccaa caaaaacgtc cagtctctga tgagttgaag
    33841 acttatattg accaacatgg agtggaggaa actcaaaaag ctcttcttga agcggaggag
    33901 aaggataagt ctatcattga agctcgtaaa ttggcaggtt tcaaacttga aacaaaacta
    33961 ttgagcgcaa cggaacttca aacaacgact agttttgatt ttcaagttct ggatgtcaag
    34021 aaggcttccc agttggaaca tctgaagaat attggtttgg aaaatctttt gaaaaatgaa
    34081 ccaagcaaat atatttcaga tagattggca aatggcgcga cagaacaata gaaaatccaa
    34141 ataaatagac tgcctgaatt gtagaaggta aggaattatg ctataatggt actattctaa
    34201 ggaaagaggg tgttagaatg ggatttactg aagaaacagt acgttttaaa ttggacgatt
    34261 ccaataaaaa agaaattagc gaaactttga cagatgttta tgcttcgttg aacgataagg
    34321 gttacaaccc aattaaccaa atcgtaggtt acgtattgag tggagaccct gcctacgttc
    34381 ctcgttataa taatgcacga aatcaaatcc gtaagtatga gcgtgatgaa atcgttgagg
    34441 aattggttcg ctactacctc aaaggacaag gagtcgatct ataacctatg agaattatgg
    34501 gattggacgt cggttcaaaa acggtagggg tggcgattag cgatccgctt ggttttacag
    34561 ctcaagggct tgaaatcatc cagataaatg aagaacaagg ccaatttggt tttgaccgcg
    34621 ttaaggaatt ggttgatact tacaaggtgg aacgatttgt agtgggcttg cctaaaaaca
    34681 tgaacaatac aagtggaccg cgcgtagaag ctagtcaagc ctacggagca aagctagaag
    34741 agttttttgg tttaccagta gactatcagg atgaacgctt gacaacagtg gctgctgagc
    34801 gcatgttgat tgaacaagca gatatcagtc gcaataagcg caagaaagtc attgataagt
    34861 tagcagctca gctgatttta caaaattatt tagatagaaa attttaatat aaaggagagg
    34921 ctatgtcaca cgatcataac cacgaccacg aagaacgtga actaatcaca ctagtagatg
    34981 agcaaggaaa tgaaaccttg tttgaaatcc ttttgacaat tgatggaaaa gaagaatttg
    35041 gtaaaaacta tgttcttcta gtaccagtta acgcagaaga agacgaagac ggacaagttg
    35101 aaatccaagc ttactcattc atcgaaaacg aagatggaac agaaggcgaa ttgcaaccaa
    35161 tcccagaaga ctcagaagac gaatggaaca tgattgaaga agtcttcaac agctttatgg
    35221 aggagtaaaa acgtccgggg gacgttttta gccctgcgct agaaattaga aacgcaggta
    35281 gtctgggaga ctgtatcagc ccaactccca gaaatgggga agagttggaa cgtccagtgg
    35341 atgtttttag cccagttcct ttaaataaga gagaactggt aggttcgggg ggacgttttt
    35401 agcccagctc ctttaaataa gatagagctg gtaagtctgg gagactgtat cagcccaact
    35461 cccagaaatg gggaagagtt ggaacgtcca gtgaacattt ttaccccaac tcttagaaat
    35521 tgagaagagt tggaacatct agtggatgtt tttagcccat attcacattc atagtggcta
    35581 gttattagct aaccaggtaa gaggtcggga cgaaaatcct ggccttgttt ttattagtaa
    35641 ccatacttta atgcgataat tgattggact tttgtcaagg agatgtgtat gtttgaagta
    35701 gaagaatggc tccatagtcg gattggttta aattttcgat caggtttggg ccgaatgcag
    35761 caagcggtgg atttgttagg aaatcctgag cagtcttacc ctattatcca cgtaacaggg
    35821 actaatggga aaggatctac cattgctttt atgagggaat tatttatggg gcatggcaaa
    35881 aaagttgcga cctttacctc ccctcatatc gtctctatca atgaccgaat ctgcattaat
    35941 gggcaaccta tagcagacgc agactttatc cgtttggctg atcaggtcaa ggagatggag
    36001 aaaacgcttc tgcaaactcc tgaccagttg tccttttttg aattgctgac cttggttgct
    36061 tttctttatt ttagggagca agaggtggat ttggttttat tagaagtggg aattggtggc
    36121 ttacttgaca cgaccaatgt ggtaactgga gagcttgctg tcatcacctc cattgggctt
    36181 gaccatcaag aaaccttggg tgatagtcta gaagcaattg cagagcagaa agctggtatt
    36241 ttcaaggctg gtaagaaggc agtgattgcg aaattgcctc cagaagctag gcttgtctgt
    36301 cagaaaaaag ccgaatcttt agctgttaac ctttatcagg caggtcaaga ttttttaatg
    36361 ctgaatggtg atttttcaag ctctttacta aatctttcac agctgaacat aggcttagaa
    36421 ggagtctatc agcaggagaa tgcagccttg gcgttgcaaa cttttcttct ttttatggga
    36481 gaaggaaagg aagctgttga tgaacaggct gtaagaaagg ccttggaaca gacccattgg
    36541 gctggtcgct tggagcgtat tcgcccacag atttacttgg atggtgctca taacctccct
    36601 gccttgactc gcttggttga gtttatcaaa gaaaaagagc aggaaggcta tcgacctcaa
    36661 atcctttttg gagccttgaa acggaaggat tatcaaggga tgttaggtta cctgactgaa
    36721 aaattgcctc aggtggaact caaggtgacc ggctttgact atcagggggc tttggacgaa
    36781 agggatgtga caggttacga tatagtttct tcttgccgag aatttatcag cgattttgaa
    36841 gaaagagcag atgctcagga tttgctgttc gttacagggt ctctctattt tatctcagaa
    36901 gtacggggct acctgctgga ccgtgagcag ataaattgac ccccttgttt gaacttgtta
    36961 tactagggga attgctggtt agagaaaatt tctctaaatt ggtagcagaa aggaaattca
    37021 tcatgaaatt aaaaagattc acactttctc ttgcttctct agcaagtttt agtctcttag
    37081 tagcttgttc acaaagagct caacaggttc aacagcctgt tgctcagcag caggtccaac
    37141 agcctgctca acaacctgct caacagaata ccaatactgc aaatgcagga ggtaaccaaa
    37201 atcaagcggc tccagtacaa aaccaacctg ttgctcaacc gaccgatatt gatgggactt
    37261 atactggtca ggatgacgga gaccgtatca ctttagtggt aactggaacg actggtacat
    37321 ggactgagct cgaatctgac ggggatcaga aagtcaaaca ggttacattt gattcagcaa
    37381 atcaacgcat gattattggc gatgatgtca aaatttacac tgtaaacggt aatcaaatcg
    37441 tcgtagatga tatggataga gacccatcgg accaaatcgt tttaactaaa taagactatg
    37501 caagtagaaa gggctggatt tttcagcctt tttactttta cctagaaaat aatcataaat
    37561 acttgccttc taccgaatac ctgcgttata ctagtatcaa ttacttgttt ttagcattca
    37621 aactatcaag gaggggatat gaaatatagg aaatttcaat tattgatgtc caagtatggc
    37681 tttagtcttt cgattatgtt acttgaactt tgtcttgttt ttggtctctt tctttattta
    37741 ggacgcatgg ctcccatttt atggattact gtcctcattc tactgagtat catcacaatc
    37801 atttcgatag tcaaccgtaa tacgactcct gagaataagg taacctggtt gttagtagcc
    37861 tttgtgccag tatttggtcc cttgctctat ctgatgtttg gtgaaaggcg attgtccaaa
    37921 aaagaaatca aacaactgaa gaagctaggc tctatgcatt tccaagaagc aaatagccag
    37981 ctactaaaag agaaattaaa agaaagtgac aaggcagctt atggagtcat caagtcctta
    38041 ttgagtatgg ataccaatgc tgacatctat gatcaaactg cctctacatt ttttcctaac
    38101 ggagaagcta tgtggaaaaa gatggtagaa gatcttaaaa aggctgagaa atttattttc
    38161 ttggaatatt acattataga agaaggtttg atgtggaatc gcatactaga tatactagag
    38221 caaaaggtag ctcagggtgt agaggttaag atgctctatg atgatatcgg ctgtatggct
    38281 actttaacag gagattatgc acatcgactt cgtcagctgg gcatcgaggc ccataaattc
    38341 aataaagtta ttcctcgttt gacagtggct tataataaca gagatcatag aaaaatattg
    38401 attgttgatg gtcagatagc ctatactggt gggatcaatc tggcagatga gtacattaac
    38461 cacgtcgaga gatttggtta ttggaaggat agtggaattc gcttagacgg actagcagta
    38521 aaagctctga cacgcttatt tttgaccact tggtacatta atcgaggaga aattagtgat
    38581 tttgatcaat atcatttaga aaatcattct atcccgagtg acggtttaac cattccatac
    38641 ggaagtggac ccaagccaat ttttcgagcg caggtaggga aaaaagttta tcagagttta
    38701 atcaatcaag caacagaatc ggtctatatt acgacacctt atttgattat agattatgat
    38761 ttaacagaga caatcaaaaa tgcagctatg agaggggtcg atgttcgaat tatcacccct
    38821 tacataccag ataagaagtt cattcagtta gtcacgagag gagcttatcc cgaccttctt
    38881 tctgctggtg ttcggattta tgagtatagt ccaggtttta ttcatagtaa gcagatgttg
    38941 gtagacgaag attttgcggt ggtggggaca atcaatctcg actaccggag cttggtacac
    39001 cattatgaaa atgcagtctt actctataaa actccttcta taagggaaat cgcccgagat
    39061 tttcgaaata tatttgcaga ttctcaggaa gtctatcctc attctatcaa aacgagctgg
    39121 tatcaaaagc ttgtaaaaga aatcgcccag ctattcgccc ctatcttata agaaatctag
    39181 aacttaggat acaaaccaga cctatttttc ttgtctttta cgaatagaaa gaaagaggag
    39241 gggaattcat gctaactaag gaagaagtga atgatatgat tgagttcaaa cagatacatt
    39301 tacaccgctt tcgggaaatt gaaacctttg tgaaactatg caaaaaatca ctcaaacagc
    39361 catcgcaagc tgacaatcct aggacttttt gatatactaa gacagataaa ttgaacagga
    39421 gaaacgatat gagtgtgtat ggtagagtag aagaagttca taaggagaat cgtgaacctc
    39481 tagaatacca aatcgaacaa gaatcgcatc atcgtgaatc aagtcgtctt cctttggtga
    39541 aaattttact atggagtacg cttgtaacgg ggataactct aggagtaccg ctattactcg
    39601 acttaatgag tgcacaagaa gtgcaggatt tttatgcagg ttgggcgctt catcagacag
    39661 ggaagattta cagcgactat tatggaagtc aaggtttgct ttattatttg ctgacttacg
    39721 tgagtcaggg cggatttttc tttgccatct ttgagtggtt agccttggta gcaggaggat
    39781 ttttcctttt tagatcagcg gacaccttga cagagcaagg agaccaagct ggacatctgg
    39841 tgactatttt ttacatgcta gttacaggtc ttgcttttgg tggaggctat gcgactcttt
    39901 tagcgcttcc tttcttattc gcagccttta gtttagttgc ggcttaccta agcaatccaa
    39961 gccatgataa gggatttgta cggattgggc tagctttggc aggcggattt ttctttgctc
    40021 ccttatcatc gctcctgttt attgctgtag tgagtttagg cttgttggtc tttaaccttg
    40081 ggcatagacg ctttgcgcat gggttttatc agtttcttgc agtggcttta ggtttttcac
    40141 ttgtctttta tccaactgcc tactatagtg ctgcaacagg aagttttggg gatgcgatta
    40201 gtggtattcg ttatcctatt gacagtattc gctttgattt tacttctaaa attttagaga
    40261 atatgttttt ttatggcttg ttgtcccttg gtttgggatt tgtggtttgt atctttttag
    40321 gtctctttca atccaaaccc tttaaactat acgtcatttc ggttcctgca agtcttgtgg
    40381 taattttagg tttgatttta cttttctttt cacaagagcc tctgcacgct tcttatttga
    40441 tggtcgtctt ccctgttttc ctacttttat tggtaaccaa tattaagagt caacagaggg
    40501 ggcgtagtgc tagaagaagc cgaagagaaa cgccagttag cctatggagt cgtttcttca
    40561 aaggaaatct atatctgcta gtttttgagt ttgtctatct tttgtctgtt ccttttttga
    40621 tgaagtttgt cctttatcca gtaccttatc aagaacgtaa tcgtcttgct gatttggtaa
    40681 aagaggagac aaatacggaa gatgctatct atgcatggga tgatactgcg actctttatc
    40741 gtaagagtga gcgcttgtcg ccatcggcga ttttgtcccc gttgcactat acagcaactg
    40801 aggaaaatcg taataagtta cttaatgact tgaaagaaaa acaacctaag gtgattgtgg
    40861 taaatgataa ggtggtagtc tggtctgaag tggaaacact cttaaaagaa aattaccaac
    40921 aagtaaagac tgattactca gagtttaaag tctataaaat taaataacca aatcaatatc
    40981 ttgtgtattt ttaaaaattt taggattttt aacacaagat attgattttt ctttttagag
    41041 tggtataata ctttttagaa agaacatttt agaaaagagc atgcatatga ttgcactaga
    41101 agaaaaaatt acaattttgc caactctctt cgtcgagaaa cgagatggga gacgtgttgt
    41161 atttgatgtg gacaagattg acaaggctct ccacaaggcg gctgacaagg ttatggatgt
    41221 gacacccctg gttgaaaaac gcctcaatga tctgactgag cgaattatta cagaaattca
    41281 tagtcgcttt ccacagggaa ttaagattta cgaaattcaa aatatcgtag aacatgaact
    41341 ccttgaagcc aaagaatatg cgctggctga ggagtatatt acttatcgga cacagaggga
    41401 ttttgagcgc tcaaaagcga cggatatcaa ctttagtatt cataaacttc tcaacaaaga
    41461 ccagacagtt gtcaatgaaa acgctaataa agacagtgat gtctttaaca ctcagcgtga
    41521 tttgacagca gggattgttg ggaaatcaat cggactgcaa atgcttccta agcacgtagc
    41581 caatgcccac caaaaggggg atatccacta tcacgatttg gactacagtc cctatacccc
    41641 tatgaccaac tgctgtttga ttgattttaa gggtatgttg gaaaatggtt ttaagattgg
    41701 aaatgcagag gtagagagtc ccaagtctat ccagactgcg acagcacaga tttctcaaat
    41761 cattgccaac gttgcttcta gccagtacgg tggctgttca gctgaccgta tcgatgaaat
    41821 tttggcgcct tatgcagaga agaattatca aaaacatctc aaagatgcag aagagtgggt
    41881 attgcctgaa aaacgggaag attacgcttg gaagaaaacg caaaaggaca tctacgatgc
    41941 catgcaatct cttgagtatg aaatcaatac tctcttcact tcaaatggac aaacaccttt
    42001 tacttcgtta ggttttggtc tgggaaccag tcgttttgaa cgagaaattc aaaaagctat
    42061 tttaaacatt cgcatcaagg gtcttggttc agaacaccgt acggctatct ttcctaaact
    42121 tattttcact ctgaaaagag gccttaattt agaggaagga actcccaact acgacatcaa
    42181 gcagttggct cttgagtgtg caaccaaacg gatgtatcca gatgttttat cttacgataa
    42241 gattgttgac ttgacaggat ccttcaaggt gcctatgggt tgccgttctt tcctccaagg
    42301 atggaaggat gaaaatggtg tagaagtcaa ttcaggtcgc atgaatctgg gtgttgtgac
    42361 ggttaatctg cctcgtattg ctcttgagtc tgaaggtgat atgaataagt tctgggaaat
    42421 cttcaacgag cgaatgaata tcgcagaaga tgctcttgtt taccgtgtcg aacgcactaa
    42481 agaggcgaca ccagcgaatg ctcctatcct ttatcagtac ggtgcttttg gccatcatct
    42541 aggtaaagaa gaaagtgttg accagctctt taagaatcgt cgtgcgaccg tttcgctggg
    42601 ctatatcggc ttgtatgaag tagcgacagt tttctttggt aacagctggg aaagtaatcc
    42661 agatgctaag gaattcacgc tagacatcat tcacgatatg aaacgccgtg tagaagagtg
    42721 gtcagaccaa tatggctacc atttctctat ctactcaaca ccatccgaaa gtctgacaga
    42781 ccgtttctgc cgactagata tagacaagtt tggctctatt cctgatatca cagacaagga
    42841 atactacacc aactctttcc actacgatgt tcgtaaaaat ccaacaccgt ttgaaaaatt
    42901 ggactttgaa aaagtctatc cagaagcagg tgcgtcaggt ggtttcatcc attattgtga
    42961 gtatccagtc cttcagcaaa atccaaaggc cttggaagct gtctgggatt atgcttatga
    43021 ccgtgtaggc tatctaggca ccaatactcc gattgaccgt tgctacaagt gtgactttga
    43081 aggggatttt gaaccaactg agagagggtt tgcttgtcca aactgtggca atagcgaccc
    43141 taaaacagta gatgtggtga agcgaacttg tggctaccta ggtaatcctc aagcaagacc
    43201 gatggtcaac gggcgtcaca aggaaatcgc tgcgcgtgtc aaacatatga atggttcaac
    43261 gattaaaata gctgggcatc aagtaacaaa ttagaaagaa atgaaatggg aaaatatcaa
    43321 ctagacgata aggggcgcgc acaagtgacc cgttatcacg agaagcactc taaaggtgga
    43381 gctggtaaga aagaacgctt gcttagcttc agagaacaat ttttaaacaa gaacaagaaa
    43441 aaataaaagt gagagccagc tctcgctttt ctcatagtgg gaggtaagga tggaattacg
    43501 cagaccaaga ttagcggata agaaagctgt tttagatatg atgacagagt ttgaaaagag
    43561 ccaatcagcc catgatggag gattttggga tgttgaggat ttttcttacg aggagtggct
    43621 agaaggtaac cgtaataaag aaatgggaat atggctacct gaaaatcgcg ttccatcgat
    43681 acagttcgta ttgtttggtg aatcaggttg tgctctagga tttttgaatc tgcgattgag
    43741 actgaatgag gggttactga attatgctgg ccacattggc tactccatcc gtccatctga
    43801 aagaggcaag ggttatgcaa aagagactct ccgtcagggc ttgcaagttg ctaaggaaaa
    43861 gaacatcaag aaagctctgg tgacctgtag cgtgaataat cttgctagta gagcagtcat
    43921 tctagcaaat ggtggaatat ttgaggatgc tcgcaatgga gtcgagcgtt attggataga
    43981 ggtagcgaat gaataatcca aaaccacaag aatggaaaag cgaggaactt agtcaaggtc
    44041 gtatcattga ctacaaggcc tttaactttg tggacggcga aggcgtgcgt aactctctct
    44101 atgtatcagg ctgtatgttt cactgcgagg gatgttataa tgttgcgact tggtctttta
    44161 atgctggcat tccctataca gcagaattag aagagcagat catggcagat cttgctcagc
    44221 cctatgttca aggtttgact ttgttgggag gggagccttt tcttaatact gggattctct
    44281 tgccacttgt taagcggatt cggaaggaat tgccagacaa ggacatctgg tcctggaccg
    44341 gctacacttg ggaagaaatg atgttggaaa ctccagataa actggaattc ttgtcactga
    44401 ttgacattct tgtcgatgga agatatgatc gaactaagag aaatcttatg ctccagtttc
    44461 gaggttcgtc taaccaacga attatcgatg tgcaaaaatc gctcaaaagt gggcaagtag
    44521 tgatttggga caagctcaat gacggaaaag aaagctatga acaggtgaag agagaatgaa
    44581 gaaaaaagac ttagtagacc aactagtctc agagatcgag acggggaaag tcaggacact
    44641 gggaatatac ggtcatggag cttcaggtaa atcaaccttt gcacaggaat tgtaccaagc
    44701 tttagattct actacagtaa atttgctaga gacagatcct tatatcacct caggacgcca
    44761 tctggtagta cccaaggacg cgccgaatca aaaggtgaca gccagtctgc cagtggcgca
    44821 tgaactggag agtttgcaga gagatatcct tgccttgcag gcgagtatgg atgtcttgac
    44881 aattgaagaa ccttggaagg ctagtgaggt cttgtctgga gccaaaccaa ttttgattgt
    44941 cgaagggatg tctgttggct ttctacccaa ggaactcttt gaaaaaacca tctgtttcta
    45001 cacggatgag gagaccgaat taaagcgacg ccttgctaga gatacgactg tgagaaatcg
    45061 cgatgcatcc tttatattgg ctagccatca gatgagacgg gagcagtatc tgcgatacta
    45121 taaagaaact gagtctaagg cggatatctt agtggaccaa tcagaagata aatttgatgt
    45181 caagaggact taacttatgt atagaagaaa tatagaagaa aatccctaat tttagaaaga
    45241 aaaagtagga aaacagtttc atccccaaaa aacgaaaaaa cctaacaaat cccttgcaat
    45301 cgcaggggat ttgtgttatt ctattatggt gctgtaaatt acagccttag ttttgatgca
    45361 agaggttgcg acacgctcgg ttgcattgcc acgcaacacc gcgtcggttt tcttgtggag
    45421 ctagcctatt atcttaaata gacgaaaagg agaaaaagat ggcaaacaaa aaaatccgta
    45481 tccgtttgaa agcttacgaa caccgtacgc ttgacacagc ggctgcaaaa atcgtagaat
    45541 cagctactcg tacaggtgca caagttgcgg gtccaatccc acttccaact gaacgtagcc
    45601 tctacacaat cattcgtgcg actcacaaat acaaagactc tcgcgaacaa tttgaaatgc
    45661 gtacacacaa acgtttgatc gatatcgtta acccaactca aaaaacagtt gatgccttga
    45721 tgaaattgga tcttccaagt ggtgtaaacg tagaaatcaa actttaatct aaaatataaa
    45781 agagcagagg ctggtgtttc aatctaattg aacacgggct aaactcggtg tgaaaaagat
    45841 aaacttcctc gcgtctgcta gacactgtgt cagtttccta ttttcacgtt gagtttgacg
    45901 ccctttgtat cttagacttg agcataaaaa acgctcgtta aaaacttttt gaataaaaaa
    45961 tatagaaaag gaactatttt ctcatgacaa aaggaatctt agggaaaaaa gtgggaatga
    46021 ctcaaatctt cactgaagct ggcgaattga tccctgtaac agttattgaa gcaactccaa
    46081 acgttgttct tcaagttaaa actgttgaaa cagacggata caacgctatc caagttggtt
    46141 tcgatgacaa acgcgaagta ttgagcaaca aacctgctaa aggacatgta gcgaaagcta
    46201 acacggctcc taagcgcttc attcgtgaat tcaaaaacgt tgaaggcttg gaagttggtg
    46261 ctgaaattac agttgaaaca ttcgcagctg gagacgttgt tgacgtaact ggtacttcta
    46321 aaggtaaagg tttccaaggt gttatcaaac gccacggaca atcacgtgga ccaatggctc
    46381 acggttctcg ttaccaccgt cgtccaggtt ctatgggacc tgttgcacct aaccgcgtat
    46441 tcaaaggtaa aaaccttgca ggacgtatgg gtggtgaccg cgtaacaatt caaaatcttg
    46501 aagttgtaca agttgttcca gaaaagaacg ttatccttat caaaggtaac gtaccaggtg
    46561 ctaagaaatc tcttatcact atcaaatcag cagttaaagc tggtaaataa taaagaaagg
    46621 ggaaatcagt cacaatggca aacgtaacat tatttgacca aactggtaaa gaagctggcc
    46681 aagttgttct tagcgatgca gtatttggta tcgaaccaaa tgaatcagtt gtgtttgatg
    46741 taatcatcag ccaacgcgca agccttcgtc aaggaacaca cgctgttaaa aaccgctctg
    46801 cagtatcagg tggtggacgc aaaccatggc gtcaaaaagg aactggacgt gctcgtcaag
    46861 gttctatccg ctcaccacaa tggcgtggtg gtggtgttgt cttcggacca actccacgtt
    46921 catacggcta caaacttcca caaaaagttc gtcgcctagc tcttaaatca gtttactctg
    46981 aaaaagttgc tgaaaacaaa ttcgtagctg tagacgctct ttcatttaca gctccaaaaa
    47041 ctgctgaatt tgcaaaagtt cttgcagcat tgagcatcga ttctaaagtt cttgttatcc
    47101 ttgaagaagg aaatgaattc gcagctcttt cagctcgtaa ccttccaaac gtgaaagttg
    47161 caactgctac aactgcaagt gttcttgaca tcgcaaatag cgacaaactt cttgtcacac
    47221 aagcagctat ctctaaaatc gaggaggttc ttgcataatg aatttgtatg atgttatcaa
    47281 aaaacctgtc atcactgaaa gctcaatggc tcaacttgaa gcagggaaat atgtatttga
    47341 agttgacact cgtgcacaca aacttttgat caagcaagct gttgaagctg ctttcgaagg
    47401 tgttaaagtt gccaatgtta acacaatcaa cgtaaaacca aaagctaaac gtgttggacg
    47461 ttacactggt tttactaaca aaactaaaaa agctatcatc acacttacag ctgattctaa
    47521 agcaatcgag ttgtttgctg ctgaagctga ataatctaag gaggaaatat cgtgggaatt
    47581 cgtgtttata aaccaacaac aaacggtcgc cgtaatatga cttctttgga tttcgctgaa
    47641 atcacaacaa gcactcctga aaaatcattg cttgttgcat tgaagagcaa ggctggtcgt
    47701 aacaacaacg gtcgtatcac agttcgtcac caaggtggtg gacacaaacg tttctaccgt
    47761 ttggttgact tcaaacgtaa taaagacaac gttgaagcag ttgttaaaac aatcgagtac
    47821 gatccaaacc gttctgcaaa catcgctctt gtacactaca ctgacggtgt gaaagcatac
    47881 atcatcgctc caaaaggtct tgaagtaggt caacgtatcg tttcaggtcc agaagcagat
    47941 atcaaagtcg gaaacgctct tccacttgct aacatcccag ttggtacttt gattcacaac
    48001 atcgagttga aaccaggtcg tggtggtgaa ttggtacgtg ctgctggtgc atctgctcaa
    48061 gtattgggtt ctgaaggtaa atacgttctt gttcgtcttc aatcaggtga agttcgtatg
    48121 attcttggaa cttgccgtgc tacagttggt gttgtcggaa acgaacaaca tggacttgta
    48181 aaccttggta aagcaggacg tagccgttgg aaaggtatcc gcccaacagt tcgtggttct
    48241 gtaatgaacc ctaacgatca cccacacggt ggtggtgaag gtaaggcacc agttggtcgt
    48301 aaagcaccat ctactccatg gggcaaacct gctcttggtc ttaaaactcg taacaagaaa
    48361 gcgaaatctg acaaacttat cgttcgtcgt cgcaacgaga aataatatta aactagtcgc
    48421 ttaagcaact agtaaatccg ccagctcggt agcgctccat aggagtgcaa gccgctgtgg
    48481 tacaacattt aaaggagaaa atataaaaat gggacgcagt cttaaaaaag gacctttcgt
    48541 cgatgagcat ttgatgaaaa aagttgaagc tcaagctaac gacgaaaaga aaaaagttat
    48601 taaaacttgg tcacgtcgat caacgatctt cccaagtttc attggttaca ctattgcagt
    48661 ttatgacgga cgtaaacacg tacctgttta catccaagaa gacatggtag gccacaaact
    48721 tggtgaattt gcaccaactc gtacttacaa aggtcacgct gcagacgaca agaaaacacg
    48781 tagaaaataa ggagaacata aatggcagaa attacttcag ctaaagcaat ggctcgtaca
    48841 gtacgtgttt cacctcgtaa atcacgtctt gttcttgata acatccgtgg taaaagcgta
    48901 gccgatgcaa tcgcaatctt gacattcact ccaaacaaag ctgctgaaat catcttgaaa
    48961 gttttgaact cagctgtagc taacgctgaa aacaactttg gtttggataa agctaacttg
    49021 gtagtatctg aagcattcgc aaacgaagga ccaactatga aacgtttccg tccacgtgcg
    49081 aaaggttcag cttcaccaat caacaaacgt acagctcaca tcactgtagc tgttgcagaa
    49141 aaataaggag gtaaaatcgt gggtcaaaaa gtacatccaa ttggtatgcg tgtcggcatc
    49201 atccgtgatt gggatgccaa atggtatgct gaaaaagaat acgcggatta ccttcatgaa
    49261 gatcttgcaa tccgtaaatt cgttcaaaaa gaacttgctg acgcagcagt ttcaactatt
    49321 gaaatcgaac gcgcagtaaa caaagttaac gtttcacttc acactgctaa accaggtatg
    49381 gttatcggta aaggtggtgc taacgttgat gcactccgtg caaaacttaa caaattgact
    49441 ggaaaacaag tacacatcaa catcatcgaa atcaaacaac ctgatttgga tgctcacctt
    49501 gtaggtgaag gaattgctcg tcaattggag caacgtgttg ctttccgtcg tgcacaaaaa
    49561 caagcaatcc aacgtgcaat gcgtgctgga gctaaaggaa tcaaaactca agtatcaggt
    49621 cgtttgaacg gtgcagatat cgcccgtgct gaaggatact ctgaaggaac tgttccgctt
    49681 cacacacttc gtgcagatat cgattacgct tgggaagaag cagatactac atatggtaaa
    49741 cttggtgtta aagtatggat ctaccgtggt gaagttcttc cagctcgtaa aaacactaaa
    49801 ggaggtaaat aaccaatgtt agtacctaaa cgtgttaaac accgtcgtga attccgtgga
    49861 aaaatgcgcg gtgaagcaaa aggtggaaaa gaagtagcat tcggtgaata cggtcttcaa
    49921 gctacaacta gccactggat cactaaccgc caaatcgaag ctgctcgtat cgccatgact
    49981 cgttacatga aacgtggtgg taaagtttgg attaaaatct tcccacacaa atcatacact
    50041 gctaaagcta tcggtgtgcg tatgggatct ggtaaagggg cacctgaagg ttgggtagca
    50101 ccagttaaac gtggtaaagt gatgttcgaa atcgctggtg tatctgaaga gattgcacgt
    50161 gaagcgcttc gacttgctag ccacaaattg ccagttaaat gtaaattcgt aaaacgtgaa
    50221 gcagaataag gagaaggcat gaaacttaat gaagtaaaag aatttgttaa agaacttcgt
    50281 ggtctttctc aagaagaact cgcgaagcgc gaaaacgaat tgaaaaaaga attgtttgaa
    50341 cttcgtttcc aagctgctac tggtcaattg gaacaaacag ctcgcttgaa agaagttaaa
    50401 aaacaaatcg ctcgtatcaa aacagttcaa tctgaagcga aataatagac tagggaagga
    50461 gaaatttcaa tggaacgcaa taatcgtaaa gttcttgttg gacgtgttgt atctgacaaa
    50521 atggacaaga caatcacagt tgtagttgaa acaaaacgta accacccagt ctatggtaaa
    50581 cgtattaact actctaaaaa atacaaagct catgatgaaa acaatgttgc caaagaaggc
    50641 gatatcgtac gtatcatgga aactcgcccg ctttcagcta caaaacgttt ccgtcttgta
    50701 gaagttgttg aagaagcggt catcatctaa tcaaacctga aaggagaaaa ctgaaatgat
    50761 tcaaacagaa actcgtttga aagtcgcaga caacagcggt gctcgcgaaa tcttgactat
    50821 caaagttctt ggtggttcag gacgtaaatt tgcaaacatc ggtgatgtta tcgtggcatc
    50881 tgtaaaacaa gctactcctg gtggtgcggt taaaaaaggt gacgttgtta aagcagttat
    50941 cgttcgtact aaatcaggtg ctcgtcgtgc tgatggttca tacatcaaat ttgacgaaaa
    51001 cgcagcagtt atcatccgtg aagacaaaac tcctcgcgga acacgtatct ttggcccagt
    51061 tgcacgtgaa ttgcgtgaag gtggtttcat gaagatcgtg tcacttgctc cagaagtact
    51121 ttaattttta ggaacaaact agtcccctag cttcaagcta gggtgccctt atgggcgtaa
    51181 gaaaaatcaa ggagaaacct aatgtttgta aaaaaaggcg acaaagttcg cgtaatcgct
    51241 ggtaaagata agggaacaga agctgttgtc cttactgccc ttccaaaagt aaacaaagtt
    51301 atcgttgaag gtgttaacat tgttaagaaa caccaacgtc caactaacga gcttcctcaa
    51361 ggtggtatca tcgagaaaga agcagctatc cacgtatcaa acgttcaagt tttggacaaa
    51421 aatggtgtag ctggtcgtgt tggatacaaa tttgtagacg gtaaaaaagt tcgctacaac
    51481 aaaaaatcag gcgaagtgct tgattaatca cgaaggaaag gagaagtata atggcaaatc
    51541 gtttaaaaga aaaatatctt aatgaagtag ttcctgcttt gacagaacaa ttcaactact
    51601 catcagtgat ggctgtgcct aaagtagata agattgtttt gaacatgggt gttggtgaag
    51661 ctgtatcaaa cgctaaaagc cttgaaaaag ctgctgaaga attggcactt atctcaggtc
    51721 aaaaaccact tatcactaaa gctaaaaaat caatcgccgg cttccgtctt cgtgaaggtg
    51781 ttgcgatcgg tgcaaaagtt acccttcgtg gtgaacgtat gtacgaattc ttggataaat
    51841 tggtatcagt ttcacttccg cgtgtacgtg acttccacgg tgtcccaaca aaatcatttg
    51901 atggacgcgg gaactacaca cttggtgtga aagaacaatt aatcttccca gaaatcaact
    51961 tcgatgacgt tgacaaaact cgtggtcttg acatcgttat cgtaacaact gctaacactg
    52021 acgaagagtc acgtgcattg cttacaggcc ttggaatgcc ttttgcaaaa taatatagga
    52081 ggtaaatcta atggctaaaa aatcaatggt agctagagag gctaaacgcc aaaaaattgt
    52141 tgaccgttat gctgaaaaac gtgctgcatt aaaggcggca ggggactacg aaggtttatc
    52201 taaattacct cgcaacgcct caccgactcg tttacataat cgttgtagag ttacggggcg
    52261 cccacattca gtttaccgca aatttggtct gagtcgtatc gcttttcgcg aacttgcgca
    52321 taaaggtcaa attcctggtg taacaaaagc atcttggtaa tttaagatat caagagtgtc
    52381 aaaactccaa gtaaaaatag gaaacttgac gaagaaacta aagtttctag gaaagtttat
    52441 ctttttcaca cagagtttag cccgggttca attgggcttg ccaatttgaa cacgagctac
    52501 agctttggca aaaaagacca atttgctttg gagcattgct tctgcattaa attgtctatt
    52561 tttgctcgtg ctgttacgct ctttgtatca tgtattaact agcaagtgca acttgcaaac
    52621 tactagtaag aggagaaaaa caaaatggtt atgactgacc caatcgcaga cttcctaact
    52681 cgtattcgta atgctaacca agctaaacac gaagtacttg aagtacctgc atcaaacatc
    52741 aaaaaaggga ttgctgaaat ccttaaacgc gaaggttttg taaaaaacgt tgaaatcatt
    52801 gaagatgaca aacaaggcgt catccgtgta tttcttaaat acggaccaaa tggtgagaaa
    52861 gttatcacta acttgaaacg tgtttctaaa ccaggacttc gtgtctacaa aaaacgtgaa
    52921 gaccttccaa aagttcttaa cggacttgga attgccatcc tttcaacttc tgaaggtttg
    52981 cttactgata aagaagcacg ccaaaagaat gttggtggtg aggttatcgc ttacgtttgg
    53041 taaaatcaag atacaaagct cgtaaagaac aaagcaaaat taggaagttg gagaagtttg
    53101 tttacaaaca agccaactta tctattttgc acagttctta gagcgtgttc agttcagctc
    53161 ttgaactaaa taagtatctg aaccccgtga aaactggccg ttctggcctg acaatttaac
    53221 aggagaaaat aaacatgtca cgtattggta ataaagttat cgtgttgcct gctggtgttg
    53281 aactcgctaa caatgacaac gttgtaactg taaaaggacc taaaggagaa cttactcgtg
    53341 agttctcaaa agatattgaa atccgtgtgg aaggtactga aataactctt caccgtccaa
    53401 acgattcaaa agaaatgaaa actatccacg gaactactcg tgcccttttg aacaacatgg
    53461 ttgttggtgt atcagaagga ttcaagaaag aacttgaaat gcgtggggtt ggttaccgtg
    53521 cacagcttca aggatctaaa cttgttttgg ctgttggtaa atctcatcca gacgaagttg
    53581 aagctccaga aggaattact tttgaacttc caaacccaac aacaatcgtt gttagcggaa
    53641 tttcaaaaga agtagttggt caaacagctg cttacgtacg tagccttcgt tcaccagaac
    53701 catataaagg taaaggtatc cgttacgttg gtgaattcgt tcgccgtaaa gaaggtaaaa
    53761 caggtaaata atgttgagtg gttgatcatc aaccaccaac ctattttcca actttgtgca
    53821 tagcacacga tttaaaacta aagaggtgaa aactgtgatt tcaaaaccag ataaaaacaa
    53881 actccgccaa aaacgccacc gtcgcgttcg cggaaaactc tctggaactg ctgatcgccc
    53941 acgtttgaac gtattccgtt ctaatacagg catctacgct caagtgattg atgacgtagc
    54001 gggtgtaacg ctcgcaagtg cttcaactct tgataaagaa gtttcaaaag gaactaaaac
    54061 tgaacaagcc gttgctgtcg gtaaactcgt tgcagaacgt gcaaacgcta aaggtatttc
    54121 agaagtggtg ttcgaccgcg gtggatatct atatcacgga cgtgtgaaag ctttggctga
    54181 tgcagctcgt gaaaacggat tgaaattcta ataggaggac actagaaaat ggcatttaaa
    54241 gacaatgcag ttgaattaga agaacgcgta gttgctgtca accgtgttac aaaagttgtt
    54301 aaaggtggac gtcgtcttcg tttcgcagct cttgttgttg ttggtgacca caatggtcgc
    54361 gtaggatttg gtactggtaa agctcaagaa gttccagaag caatccgtaa agcagtagat
    54421 gatgctaaga aaaacttgat cgaagttcct atggttggaa caacaatccc acacgaagtt
    54481 ctttcagaat tcggtggagc taaagtattg ttgaaacctg ctgtagaagg ttctggagtt
    54541 gccgctggtg gtgcagttcg tgccgttgtg gaattggcag gtgtggcaga tattacatct
    54601 aaatcacttg gttctaacac tccaatcaac attgttcgtg caactgttga aggtttgaaa
    54661 caattgaaac gcgctgaaga aattgctgcc cttcgtggta tttcagtttc tgatttggca
    54721 taagaaaggg gataaaatgg ctcaaattaa aattactttg actaagtctc caatcggacg
    54781 cattccatca caacgtaaaa ctgttgtagc acttggactt ggcaaattga acagctctgt
    54841 tattaaagaa gataacgctg ctatccgtgg tatgatcaca gcagtatctc acttagtaac
    54901 agttgaagaa gtaaactaat gaagttttag gggatgtgca ctgtaccatc ccctaaaact
    54961 agatatagtc atctatgatg acatcgtata ggcgagttga tgggggagac aaccttttct
    55021 cccttatcgg cgctagcatt ttacaaaaga ggagaaaata aaaatgaaac ttcatgaatt
    55081 gaaacctgca gaaggttctc gtaaagtacg taaccgcgtt ggtcgtggta cttcatcagg
    55141 taacggtaaa acatctggtc gtggtcaaaa aggtcaaaaa gctcgtagcg gtggcggagt
    55201 tcgccttggt tttgaaggtg gacaaactcc attgttccgt cgtcttccaa aacgtggatt
    55261 cactaacatc aacgctaaag aatacgcaat tgtgaacctt gaccaattga acgtctttga
    55321 agatggtgct gaagtaactc cagttgttct tatcgaagca ggaattgtta aagctgaaaa
    55381 gtcaggtatt aaaattcttg gtaacggtga gttgactaag aaattgactg tgaaagcagc
    55441 taaattctct aaatcagctg aagaagctat cactgctaaa ggtggttcag tagaagtcat
    55501 ctaagagagg tgacctatgt tttttaaatt attaagagaa gctcttaaag tcaagcaggt
    55561 tcgatcaaaa attttattta caatttttat cgttttggtc tttcgtatcg gaactagcat
    55621 tacagttcct ggtgtgaatg ccaatagctt gaatgcttta agtggattat ccttcttaaa
    55681 catgttgagc ttggtgtcgg ggaatgccct aaaaaacttt tcgatttttg ccctaggagt
    55741 tagtccctat atcactgctt ctattgttgt ccaactcttg caaatggata ttttacccaa
    55801 gtttgtagag tggggtaaac aaggggaagt aggtcgaaga aaattgaatc aagctactcg
    55861 ttatattgct ctagttctcg cttttgtgca atctatcggg attacagctg gttttaatac
    55921 cttggctgga gctcaattga ttaaaactgc tttaactcca caagtttttc tgacgattgg
    55981 tatcatctta acagctggta gtatgattgt cacttggttg ggtgagcaaa ttacagataa
    56041 gggatacgga aacggtgttt ccatgattat ctttgccggg attgtttcct caattccaga
    56101 gatgattcag ggcatctatg tggactactt tgtgaacgtc ccaagtagcc gtatcacttc
    56161 atctatcatt ttcgtaatca ttttgattat tactgtattg ttgattattt actttacaac
    56221 ttatgttcaa caagcagaat acaaaattcc aatccaatat actaaggttg cacaaggtgc
    56281 tccatctagc tcttaccttc cgttaaaggt aaatcctgct ggagttatcc ctgttatctt
    56341 tgccagttcg attactgcag cgcctgcggc tattcttcag tttttgagtg ccacaggtca
    56401 tgattgggct tgggtaaggg tagcacaaga gatgttggca actacttctc caactggtat
    56461 tgccatgtat gctttgttga ttattctctt tacattcttc tatacgtttg tacagattaa
    56521 tcctgaaaaa gcagcagaga gcctacaaaa gagtggtgcc tatatccatg gagttcgtcc
    56581 tggtaaaggt acagaagaat atatgtctaa acttcttcgt cgtcttgcaa ctgttggttc
    56641 cctcttcctt ggtgtgattt ccattttacc gattgcagct aaagatgtat ttggtctttc
    56701 tgatgttgtt gcctttggtg gaacaagtct cttgatcatt atctctacag gtatcgaagg
    56761 aatcaagcaa ttggaaggtt acctattgaa acgtaagtat gttggtttca tggacagaac
    56821 agaataaaag tatttactga atcagtaaat gctgagggag tggaggttta aactctgaca
    56881 tttgtaagag ttggatctcc cctcttctat tttgttttta aataggggtg aaaagacttt
    56941 ttgcttctat ttaaaaataa aataaggaga tcaaatcatg aatcttttga ttatgggctt
    57001 acctggtgca ggtaagggaa ctcaagcagc aaaaatcgta gaacaattcc atgttgcaca
    57061 tatctcaaca ggtgatatgt tccgcgctgc aatggcaaat caaactgaaa tgggtgttct
    57121 tgctaagtca tatattgaca agggtgaatt ggttcctgac gaagttacaa atggaatcgt
    57181 aaaagaacgc ctttcacaag atgatattaa agaaacagga ttcttattgg atggttaccc
    57241 acgtacaatt gaacaagctc atgccttgga caaaacattg gctgaacttg gcattgaact
    57301 agaaggtgtt atcaatattg aagtgaaccc tgacagcctc ttggaacgtt tgagtggccg
    57361 tatcatccac cgcgtaactg gagaaacttt ccacaaggtc tttaacccac cagttgacta
    57421 taaagaagaa gattactacc aacgtgaaga tgataagcct gagacagtaa aacgtcgttt
    57481 ggatgttaat attgctcaag gagaaccaat cattgctcac taccgtgcca aaggtttggt
    57541 tcatgacatc gaaggtaatc aagatatcaa tgatgtcttc tcagatattg aaaaagtatt
    57601 gacaaatttg aaataaagcg tttttcatac ttgcaaaaat tcgctacaaa tgttatactg
    57661 agatagtctg acttataatt gttgtctctg tgtctagagg catcgaatcg aaatttatgg
    57721 aggtgctttt gcgtggcaaa agacgatgtg attgaagttg aaggcaaagt agttgataca
    57781 atgccgaatg caatgtttac ggttgaactt gaaaatggac atcagatttt agcaacagtt
    57841 tctggtaaaa ttcgtaaaaa ctatattcgt attttagcgg gagatcgtgt tactgtcgaa
    57901 atgagtccat atgacttgac acgtggacgt atcacttacc gctttaaata atcgaaaaac
    57961 ttggagggat aagaaatgaa agtaagacca tcggtcaaac caatttgcga atactgtaaa
    58021 gttattcgtc gtaatggtcg tgttatggta atttgcccag caaatccaaa acacaaacaa
    58081 cgtcaaggat aagatagaaa ggagaaaaca tggctcgtat tgctggagtt gatattccaa
    58141 atgacaaacg cgtagtaatc tcattgactt atgtttatgg tatcggactt gcaacatcta
    58201 agaaaatttt ggctgctgct ggaatctcag aagatgttcg tgtacgtgat cttacatcag
    58261 atcaagaaga tgctatccgt cgtgaagtgg atgcaatcaa agttgaaggt gaccttcgtc
    58321 gtgaagtaaa cttgaacatc aaacgtttga tggaaatcgg ttcataccgt ggtatccgtc
    58381 accgtcgtgg acttcctgtc cgtggacaaa acactaaaaa caacgctcgc actcgtaaag
    58441 gtaaagctgt tgcgattgct ggtaagaaaa aataatatag gaggtaaaag tcttggctaa
    58501 accaacacgt aaacgtcgtg tgaaaaagaa tatcgaatct ggtattgctc atattcacgc
    58561 tacatttaat aacactattg ttatgattac tgatgtgcat ggtaatgcaa ttgcttggtc
    58621 atcagctggt gctcttggtt tcaaaggttc tcgtaaatct acaccattcg ctgctcaaat
    58681 ggcttctgaa gctgctgcta aatctgcaca agaacacggt cttaaatcag ttgaagttac
    58741 tgtaaaaggt ccaggttctg gtcgtgagtc agctattcgt gcgcttgctg ccgctggtct
    58801 tgaagtaaca gcaattcgtg atgtgactcc agtgccacac aatggtgctc gtcctccaaa
    58861 acgtcgccgt gtataatcat cgcattacac tgcttttcgt ttaagaggga gtaactaaat
    58921 gatcgagttt gaaaaaccaa atataacaaa aattgatgaa aataaagatt atggcaagtt
    58981 tgtaatcgaa ccacttgaac gtggctacgg tacaactctt ggtaactctc ttcgtcgtgt
    59041 acttctagct tctctaccag gagcagctgt gacatctatc aacattgatg gtgtgttaca
    59101 tgagtttgac acagttccag gtgttcgtga agacgtgatg caaatcattc tgaacattaa
    59161 aggaattgca gtgaaatcgt acgttgaaga cgaaaaaatc atcgaactgg atgttgaagg
    59221 tcctgctgaa gtaacagctg gtgacatttt gacagatagc gatattgaaa ttgtaaatcc
    59281 agatcattat ctctttacaa tcggtgaagg ttcttctcta aaagcgacta tgactgttaa
    59341 cagtggtcgt ggatatgtac ctgctgatga aaataaaaag gataatgcac cagttggaac
    59401 acttgctgta gattctattt atacaccagt tacaaaagtc aactatcaag tggaacctgc
    59461 tcgtgtaggt agcaatgatg gtttcgacaa attaaccctt gaaatcttga caaatggaac
    59521 aattattcca gaagatgctt tagggctttc agcacgtatt ttgacagaac atcttgattt
    59581 gtttacaaat cttactgaga ttgctaagtc aactgaagtg atgaaagaag ctgatactga
    59641 atctgacgac cgtattttag atcgtacgat tgaggaactg gacttgtctg tgcgttcata
    59701 caactgttta aaacgtgccg gtatcaatac tgtgcatgat ttgacagaaa aatctgaagc
    59761 agagatgatg aaagtacgaa atcttggacg caagagtttg gaagaagtga aactcaaact
    59821 cattgatttg ggtcttggat taaaagataa ataaaggagg aatacatggc ttaccgtaaa
    59881 ctaggacgca ctagctcaca acgtaaagca atgcttcgcg atttgacaac tgaccttttg
    59941 atcaacgaat caatcgtgac aactgaagct cgtgctaaag aaatccgtaa aactgttgaa
    60001 aaaatgatta ctctaggtaa acgtggtgat ttgcatgcac gtcgtcaagc agctgctttc
    60061 gtacgtaatg aaatcgcatc tgaaaactat gatgaagcaa ctgataagta cacttctact
    60121 acagcacttc aaaaattgtt ctcagaaatc gcacctcgtt atgctgaacg taacggtgga
    60181 tacactcgta tccttaaaac tgaaccacgt cgtggtgatg cagcgccaat ggcgatcatc
    60241 gaattagtat aaaatcatca attttgttga gtgttatgat gatggagtct tgtgctctta
    60301 gtctagctct ggtctaccgc taggatttcg gtcctagcgg gaacactcat cataagttgg
    60361 gatagtagac gcttgtttac gaaattgttt ttttcttaag aacaacttcg taagcaggcg
    60421 tttttgagta ttttcgttag aattatgcta tactatttga aaagaatcct gtttaatgtt
    60481 aaggtttctt attttaagaa gaattggagt ttacttatga aagcgattat aactgttgtt
    60541 ggtaaagata aatctggaat tgttgcaggt gtttctggta aaattgcaga attaggattg
    60601 aatattgacg atatctctca aactgtattg gatgaatatt ttacgatgat ggctgttgta
    60661 tctagtgatg aaaagcaaga ttttacctat cttcgtaatg aatttgaagc ttttgggcaa
    60721 actttgaatg taaaaatcaa tattcagagt gcagcgattt tcgaagctat gtataatatc
    60781 taggaggtca tcatggatat tagacaagtt actgaaacca tcgccatgat tgaggagcaa
    60841 aacttcgata ttagaaccat taccatgggg atttctcttt tggactgtat cgatccagat
    60901 atcaatcgtg ctgcggagaa aatctatcaa aaaattacga caaaggcggc taatttagta
    60961 gctgttggtg atgaaattgc ggctgagttg ggaattccta tcgttaataa gcgtgtatcg
    61021 gtgacaccta tttctctgat tggggcagcg acagatgcga cggactacgt ggttctggca
    61081 aaagcgcttg ataaggctgc gaaagagatt ggtgtggact ttattggtgg tttttctgcc
    61141 ttagtacaaa aaggttatca aaagggagat gagattctca tcaattccat tcctcgcgct
    61201 ttgactgaga cggataaggt ctgctcgtca gtcaatatcg gctcaaccaa gtctggtatt
    61261 aatatgacgg ctgtggcaga tatgggacga attatcaagg aaacggcaaa tctttcagat
    61321 atgggagcgg ctaagttggt tgtattcgct aatgctgttg aggacaatcc atttatggcg
    61381 ggtgcctttc atggtgttgg ggaagcagat gttatcatca atgtcggagt ttctggtcct
    61441 ggtgtggtga aacgtgcttt ggaaaaagtt cgtggacaga gctttgatgt agtagccgaa
    61501 acagttaaga aaactgcctt taaaatcact cgtatcggtc aattggttgg tcaaatggcc
    61561 agtgagagac tgggtgtgga gtttggtatt gtggacttga gtttggcacc aacccctgcg
    61621 attggagact ctgtggcacg tgtccttgag gaaatggggc tagaaacagt tggcacgcat
    61681 ggaacgacgg ttgccttggc cctcttgaac gaccaagtta aaaagggtgg agtgatggcc
    61741 tgcaaccaag tcggtggttt atctggcgcc tttatccctg tttctgagga tgaaggaatg
    61801 attgctgcag tgcaaaatgg ctctcttaat ttagaaaaac tagaagctat gacggctatc
    61861 tgttctgttg gattggatat gattgccatc ccagaagata cgcctgctga aaccattgcg
    61921 gctatgattg cggatgaagc agcaatcggt gttatcaaca tgaaaacaac agctgttcgt
    61981 atcattccca aaggaagaga aggcgatatg attgagtttg gtggtctatt aggaactgca
    62041 cctgttatga aggttaatgg ggcttcgtct gtcgacttca tctctcgcgg tggacaaatc
    62101 ccagcaccaa ttcatagttt taaaaattaa gaaaatagga gaaattttaa gttctattta
    62161 agattagatg tgtatactat aatcattaaa taaagacctc ctaatattat ttgaaacaga
    62221 taacactgaa ttagtttgaa tttgattttc atctaatatc tttatttaat gaactcctaa
    62281 actttttcat aataatctcc ttcaaaagtc gcctgtatgg gtggctttta ttttatcatt
    62341 catgatataa tagaagcaaa cggaggacgg aaaatggtaa aagtacgatt gtatttggta
    62401 cgtcatggca agaccatgtt taacacgatt ggtcgcgcgc aaggttggag cgatactccc
    62461 ttaactgctg aaggtgaacg agggattcaa gagttaggaa tcggtttgcg agaatctgat
    62521 ctacagtttg agcgcgctta ttcgagtgat tctggtcgta ccattcagac catgggaatt
    62581 atccttgaag aacttggctt gcaggggaaa atcccttatc gcatggacaa gcgtatcaga
    62641 gaatggtgtt tcggtagttt tgatggagcc tatgatggcg atcttttcat gggcattatt
    62701 cctcgtatct ttaatgtgga ccacgttcac caattgtctt atgctgaact ggctgagggc
    62761 ttggtagagg tcgatacagc tggttgggct gaaggctggg aaaaactcag tggccgaatc
    62821 aaggaaggct ttgaaatgat tgcaaaagaa atggaagatc aaggtggagg taacgccctt
    62881 gttgtcagcc atggaatgac tattggaacc attgtttatc tgattaatgg catgcatccg
    62941 catggtctag ataatggtag cgtgacgatt cttgaatatg aggacggtca gtttagggtt
    63001 gaagttgtcg gtgaccgtag ttaccgagag ctaggatgtg agaagatgga agaaggctct
    63061 atttaatcag tctagacttg cttgccatga gctagggatt tgataagaat atcaagataa
    63121 gaaaaaacag ccgagggcac tcctttcggc tgtttttgat gtggaaaact aaagtgtaat
    63181 gctattgctt ttagagattt tcataaacaa gagcaaggaa cctactgtta gaacagtcag
    63241 gatagttgac aaggctgcgg ctacaccgta atttcctctg agaacctctg tataaatagc
    63301 tacagtcatt gttcttgttt tgacattgta gaggaggata gaagtagaga gttttgaaat
    63361 cattgtgacc caagataaga tggctccaga aatgatacca gatagcatca ttggagttgt
    63421 aatcttagca aaggtattga gacgactact tcctaagctt tcagcagctt cttcaatact
    63481 tggtgctatt tgttgtaagc tagcaacaga tgagcgaata gtataaggta atcttctgac
    63541 agatagagac ataatcaaga tgaaagcagt ccctgtaatc ataagaaatc cacttccaaa
    63601 tagaccagta ttgaaggaag aaatgaaggc aatccctaga acggttcctg gtacaatata
    63661 aggtaccata ctgaggctgt caattaagtt tgtaaacaaa ttccgttttc taacggctag
    63721 gtaggagata aatgtcgcaa atagaacaac tagaactaag gcaatcaaag ggatacgaat
    63781 ggtattgaaa atagcagatc ccatacgatt gaaagctacc ttgtaactgt ttggagaata
    63841 acctttaaca gataccatac ctgatgtttt taggaaagag gtataaatta agtagatttg
    63901 aggtaaaaca gagataaaga taattccgta gactgttgca taaatggcag ctatttttcc
    63961 ttttgtagtt tttttaggct caattggatg gagcagattc atgctgaaac tgtagcggtt
    64021 tgcaatgtgt ttttggataa ggaaaattgc caaggcaatg ataatcgcca taattgcaaa
    64081 agcagaattt cctccaacct cgctaataaa ttgggtataa atcaggacag ggaaagtccg
    64141 atatccttcg tcaatcaaca taggcgttcc aaagtctgag aatgctctca taaatacaag
    64201 caaggagctg ctagtaaggt tggaactagg agaggtaaaa caaccgttac gatacgctta
    64261 aatccgaagg accccatgct ttcagctgct tcaagtagag aattgtcaat actgttcatt
    64321 gttccagcaa catatagaaa taccagtggg aatagttgca gtgtaaagac aagtacaatt
    64381 cctttgaatc cataaatatc gatagctgga agatgaaggg catttgtcaa aaatttagtg
    64441 atgacctcat ttcgtcccag caagagaatt caggagtagg ctcctacgaa aggagctgac
    64501 atggaagcaa tgataatcaa tatttgtaga aatttcttcc ccttgaagtc atacatagag
    64561 aagagataag ctaatagggt tcctacaact aaggaagtga cagtagcggt aatggaaacc
    64621 ctgaaactgt tgactagtgt ctcagagtag taggttttac taaagaaagt gacaaaatta
    64681 gctagtgaga attatccttc atgtataagt gcttacttga gcacggtaac gataggataa
    64741 acgagaaaga caagataggt aagaaagagg aggctgtcca aatatttagt tttttacgtt
    64801 ccatggttga ctccttttat caggttttgg gaaccatctg cagaaaagat gtttaatttt
    64861 tgcgtattga ttcgtagacg aatacgattg tctttttgta gatcttcttc aaaagttgat
    64921 tcttcactaa cttgaatttt tgaggcaaaa cctgtctcaa tgaaatactc cgtatttagt
    64981 ccaagataga cgctatcgct aatagttcct tcgatatctc cagattcatc tttgataaac
    65041 tcttcgggac gaatgcttac atgaatagct tgctcctcaa cctgatcaag agctagcatt
    65101 cgaagggcat agccatctga aaagacgata taagcgccgt cgctccgttt ttcaagattg
    65161 gcagggataa tatttgtgcg tccgataaag gttgccacaa actcattagt tggtttatga
    65221 tagagttctt ttggtcggcc gatttgttgg atcaccccat ctttcataac agcaatttgg
    65281 tctgaaatag ccatggcttc ttcttggtcg tgggttacat aaacagttgt aattcccact
    65341 tcgtgttgga tttctcggat ggcttgacgc atatccaagc gaagtttggc ctccagatta
    65401 ctaagtggct cgtccatgag gagaacactt ggattaaccg ctaaggcgca tgccaaggtg
    65461 acacgttgtt gttgtccacc actgagttta tcgggctttc gatccgcata ttgagcaatt
    65521 tgcatgagtt caagatactt gttggtctgt tgaatcaatt cttcttttgg aaccttcttt
    65581 tgcataagac caaaagcaac gttgtctcgg acagtcaaat gtgggaaaat agcgtagttt
    65641 tggaaaacca tcccgatatt gcgtttgctg ggttccatat tattgatttt tgtatcatcg
    65701 aagtaaaatt ctccaccttc gatactgttg aaacctgcaa tcatacgaag aagggtcgtt
    65761 ttcccacatc ctgaagctcc aagaagggta aagagacttc cttttggaat tgtaatgttc
    65821 aaattctcaa taacagggac atcgtggtag atttttttgg cgttaataat tttgatctca
    65881 ctcatagtga acctctttta ctgtttagat tggatatctg taaagacttc gttgtatttc
    65941 ttaacgatat ctgatttatt cttgatgaca taatcataat cttcagtgag tgttttgatt
    66001 ttgtcaattg gtttcatgtt ttcgcttgtt ttagcatttt tacgaacagg acggttagta
    66061 gtggttgtac caagtgtatc ttgtacttct tgagagataa taaaatcgat aaatttcttg
    66121 gcattttcca tatttttaga ttttttaacg atagcagcac tagcaggtag gaagacggtt
    66181 ccttcttttg gatagactac cttaatgtta gctccgtcat ttaagagttt aactgctgga
    66241 tcttcataag agagaccaac agtcatttct tcatcagcga ctgctttata gacaccagat
    66301 gaacttaaac cgattttata gtatattgaa actagaatag tacacatcta cttctaaaat
    66361 attgttagaa atcgatttga ctgtcctgat taatttgtcc tgttcttatt tcattttact
    66421 ataccatcaa taagtgtgaa aagatctttt acataagacc aagccttatc atctttgtaa
    66481 ccaccttgag cttgtagcat atttgttaat tgagcaaagg tgctagaaga gtttgctggg
    66541 tcagcagttg cgattttttc ttttagttca ggtttgagaa gatcgttata tccttcgatg
    66601 ttcatgcctt tagttaaatc agggttgacg attaaaacac taccatctag tgtataagga
    66661 gtagagaagc cagttgtgtt ttgatattct ttgataacat tatcattttc ttttgaagta
    66721 tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc aaagataaca
    66781 tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc agtaccagct
    66841 tgaatcagtt ctactttgat accatatttt tcttcaaagg caggaatagt tgctccaatt
    66901 aagtcctctg agtttggtca ataaacgact agcgaaccac cgtctccttt atcagatgaa
    66961 ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt ctttttcatg
    67021 atgggatatc tccgttgtgt tatttaagtt tattttaaaa aaatgtaagc gtttttaaaa
    67081 cctacaattc ta
//
LOCUS       DAVMCG010000008        62874 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVMCG010000008 DAVMCG010000000
VERSION     DAVMCG010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.008"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(1..463)
                     /locus_tag="VYP66_000619"
                     /pseudo
     CDS             complement(1..463)
                     /locus_tag="VYP66_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(453..650)
                     /locus_tag="VYP66_000620"
     CDS             complement(453..650)
                     /locus_tag="VYP66_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850217.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(654..1448)
                     /locus_tag="VYP66_000621"
     CDS             complement(654..1448)
                     /locus_tag="VYP66_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850218.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(1856..2281)
                     /locus_tag="VYP66_000622"
     CDS             complement(1856..2281)
                     /locus_tag="VYP66_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850219.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(2410..2793)
                     /locus_tag="VYP66_000623"
     CDS             complement(2410..2793)
                     /locus_tag="VYP66_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850220.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(2815..3021)
                     /locus_tag="VYP66_000624"
     CDS             complement(2815..3021)
                     /locus_tag="VYP66_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850221.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(3008..3181)
                     /locus_tag="VYP66_000625"
     CDS             complement(3008..3181)
                     /locus_tag="VYP66_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850222.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(3527..4483)
                     /gene="lytA"
                     /locus_tag="VYP66_000626"
     CDS             complement(3527..4483)
                     /gene="lytA"
                     /locus_tag="VYP66_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1850223.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(4859..6229)
                     /locus_tag="VYP66_000627"
     CDS             complement(4859..6229)
                     /locus_tag="VYP66_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1850224.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLSMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(6536..7702)
                     /gene="recA"
                     /locus_tag="VYP66_000628"
     CDS             complement(6536..7702)
                     /gene="recA"
                     /locus_tag="VYP66_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1850225.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(7757..9013)
                     /locus_tag="VYP66_000629"
     CDS             complement(7757..9013)
                     /locus_tag="VYP66_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1850226.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FTLRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGNPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(9098..10114)
                     /locus_tag="VYP66_000630"
     CDS             complement(9098..10114)
                     /locus_tag="VYP66_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1850227.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNLLRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(10122..10640)
                     /locus_tag="VYP66_000631"
     CDS             complement(10122..10640)
                     /locus_tag="VYP66_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850228.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(10630..11073)
                     /gene="tsaE"
                     /locus_tag="VYP66_000632"
     CDS             complement(10630..11073)
                     /gene="tsaE"
                     /locus_tag="VYP66_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1850229.1"
                     /translation="MYTKNEEELQALGESLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(11159..11779)
                     /locus_tag="VYP66_000633"
     CDS             complement(11159..11779)
                     /locus_tag="VYP66_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850230.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(12162..13025)
                     /locus_tag="VYP66_000634"
     CDS             complement(12162..13025)
                     /locus_tag="VYP66_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850231.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            13214..13384
                     /locus_tag="VYP66_000635"
     CDS             13214..13384
                     /locus_tag="VYP66_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850232.1"
                     /translation="MKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            13834..15849
                     /locus_tag="VYP66_000636"
     CDS             13834..15849
                     /locus_tag="VYP66_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1850233.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVRDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKNLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKAIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTTGEGLLSYNLILLSISLFFTQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            15851..16483
                     /locus_tag="VYP66_000637"
     CDS             15851..16483
                     /locus_tag="VYP66_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850234.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(17411..17824)
                     /gene="ndk"
                     /locus_tag="VYP66_000638"
     CDS             complement(17411..17824)
                     /gene="ndk"
                     /locus_tag="VYP66_000638"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1850235.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(17935..21612)
                     /gene="rpoC"
                     /locus_tag="VYP66_000639"
     CDS             complement(17935..21612)
                     /gene="rpoC"
                     /locus_tag="VYP66_000639"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1850236.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(21645..25256)
                     /gene="rpoB"
                     /locus_tag="VYP66_000640"
     CDS             complement(21645..25256)
                     /gene="rpoB"
                     /locus_tag="VYP66_000640"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1850237.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TSEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVIAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            25672..25742
                     /locus_tag="VYP66_000641"
     tRNA            25672..25742
                     /locus_tag="VYP66_000641"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25704..25706,aa:Cys,seq:gca)
     gene            complement(25940..27271)
                     /locus_tag="VYP66_000642"
     CDS             complement(25940..27271)
                     /locus_tag="VYP66_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1850238.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(27562..28386)
                     /gene="endA"
                     /locus_tag="VYP66_000643"
     CDS             complement(27562..28386)
                     /gene="endA"
                     /locus_tag="VYP66_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1850239.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(28425..28613)
                     /locus_tag="VYP66_000644"
     CDS             complement(28425..28613)
                     /locus_tag="VYP66_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1850240.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(28606..29889)
                     /gene="murA"
                     /locus_tag="VYP66_000645"
     CDS             complement(28606..29889)
                     /gene="murA"
                     /locus_tag="VYP66_000645"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1850241.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(29913..30143)
                     /locus_tag="VYP66_000646"
     CDS             complement(29913..30143)
                     /locus_tag="VYP66_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1850242.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(30201..31238)
                     /locus_tag="VYP66_000647"
     CDS             complement(30201..31238)
                     /locus_tag="VYP66_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1850243.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(31222..31710)
                     /gene="coaD"
                     /locus_tag="VYP66_000648"
     CDS             complement(31222..31710)
                     /gene="coaD"
                     /locus_tag="VYP66_000648"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1850244.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(31700..32239)
                     /gene="rsmD"
                     /locus_tag="VYP66_000649"
     CDS             complement(31700..32239)
                     /gene="rsmD"
                     /locus_tag="VYP66_000649"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1850245.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLIFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(32304..33296)
                     /locus_tag="VYP66_000650"
     CDS             complement(32304..33296)
                     /locus_tag="VYP66_000650"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1850246.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(33408..34091)
                     /locus_tag="VYP66_000651"
     CDS             complement(33408..34091)
                     /locus_tag="VYP66_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1850247.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(34147..34887)
                     /locus_tag="VYP66_000652"
     CDS             complement(34147..34887)
                     /locus_tag="VYP66_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1850248.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            34921..35199
                     /locus_tag="VYP66_000653"
     CDS             34921..35199
                     /locus_tag="VYP66_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1850249.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            35277..36203
                     /gene="yidC"
                     /locus_tag="VYP66_000654"
     CDS             35277..36203
                     /gene="yidC"
                     /locus_tag="VYP66_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1850250.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(36278..37072)
                     /gene="pflA"
                     /locus_tag="VYP66_000655"
     CDS             complement(36278..37072)
                     /gene="pflA"
                     /locus_tag="VYP66_000655"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1850251.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(37198..38448)
                     /locus_tag="VYP66_000656"
     CDS             complement(37198..38448)
                     /locus_tag="VYP66_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1850252.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYHPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEVVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(38515..39342)
                     /gene="purR"
                     /locus_tag="VYP66_000657"
     CDS             complement(38515..39342)
                     /gene="purR"
                     /locus_tag="VYP66_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1850253.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(39609..40550)
                     /locus_tag="VYP66_000658"
     CDS             complement(39609..40550)
                     /locus_tag="VYP66_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1850254.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(40540..41796)
                     /locus_tag="VYP66_000659"
     CDS             complement(40540..41796)
                     /locus_tag="VYP66_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1850255.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(41798..42460)
                     /locus_tag="VYP66_000660"
     CDS             complement(41798..42460)
                     /locus_tag="VYP66_000660"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1850256.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(42423..43079)
                     /locus_tag="VYP66_000661"
     CDS             complement(42423..43079)
                     /locus_tag="VYP66_000661"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1850257.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(43090..43968)
                     /gene="rsgA"
                     /locus_tag="VYP66_000662"
     CDS             complement(43090..43968)
                     /gene="rsgA"
                     /locus_tag="VYP66_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1850258.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(43970..44842)
                     /gene="rsmA"
                     /locus_tag="VYP66_000663"
     CDS             complement(43970..44842)
                     /gene="rsmA"
                     /locus_tag="VYP66_000663"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1850259.1"
                     /translation="MRIADYRVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(44973..45281)
                     /locus_tag="VYP66_000664"
     CDS             complement(44973..45281)
                     /locus_tag="VYP66_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850260.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(45274..45915)
                     /locus_tag="VYP66_000665"
     CDS             complement(45274..45915)
                     /locus_tag="VYP66_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850261.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(45917..47947)
                     /locus_tag="VYP66_000666"
     CDS             complement(45917..47947)
                     /locus_tag="VYP66_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1850262.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(48024..48320)
                     /locus_tag="VYP66_000667"
     CDS             complement(48024..48320)
                     /locus_tag="VYP66_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1850263.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(48640..49551)
                     /locus_tag="VYP66_000668"
     CDS             complement(48640..49551)
                     /locus_tag="VYP66_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850264.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     EDLFYEQLPNEEKVWFEATRATIDVIRSGRPEYGETVLDDYFKTIYDKELFLINELEV
                     INLYFAIVLTKIKQGQNQIEEINRIHSFLVRLTNHVELIASEYLFALSNTLFSGLACL
                     DNLSSYDSLGAYIFSLNHIMEKTQDFQKKPIILMLEWKLSLIINNDYVSAEQFYQKSK
                     LFADIIENSYLVTMLEKQWQEDLKKYL"
     gene            complement(49623..50183)
                     /gene="rnmV"
                     /locus_tag="VYP66_000669"
     CDS             complement(49623..50183)
                     /gene="rnmV"
                     /locus_tag="VYP66_000669"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1850265.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(50183..50956)
                     /locus_tag="VYP66_000670"
     CDS             complement(50183..50956)
                     /locus_tag="VYP66_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1850266.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELLLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(51261..51926)
                     /locus_tag="VYP66_000671"
     CDS             complement(51261..51926)
                     /locus_tag="VYP66_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1850267.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKLENTPGGDKGGNTGSSD
                     ANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGVQAIAMVTVPKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVVATSGFALLGRKTR
                     RRK"
     gene            complement(52189..52323)
                     /gene="rpmH"
                     /locus_tag="VYP66_000672"
     CDS             complement(52189..52323)
                     /gene="rpmH"
                     /locus_tag="VYP66_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1850268.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(52468..53682)
                     /locus_tag="VYP66_000673"
     CDS             complement(52468..53682)
                     /locus_tag="VYP66_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1850269.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKKLLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(53838..54131)
                     /locus_tag="VYP66_000674"
     CDS             complement(53838..54131)
                     /locus_tag="VYP66_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850270.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            54293..54745
                     /locus_tag="VYP66_000675"
     CDS             54293..54745
                     /locus_tag="VYP66_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1850271.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(54780..56168)
                     /locus_tag="VYP66_000676"
     CDS             complement(54780..56168)
                     /locus_tag="VYP66_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1850272.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            56234..57196
                     /locus_tag="VYP66_000677"
     CDS             56234..57196
                     /locus_tag="VYP66_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1850273.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(57225..57428)
                     /locus_tag="VYP66_000678"
     CDS             complement(57225..57428)
                     /locus_tag="VYP66_000678"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850274.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHVFEVVDRTDEVSNHTYGKAT"
     gene            complement(57492..58502)
                     /gene="ccpA"
                     /locus_tag="VYP66_000679"
     CDS             complement(57492..58502)
                     /gene="ccpA"
                     /locus_tag="VYP66_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1850275.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(58927..59526)
                     /locus_tag="VYP66_000680"
     CDS             complement(58927..59526)
                     /locus_tag="VYP66_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850276.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(59528..60625)
                     /locus_tag="VYP66_000681"
     CDS             complement(59528..60625)
                     /locus_tag="VYP66_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1850277.1"
                     /translation="MLERLKSIHYMFWASLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGLMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKIDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(60625..61362)
                     /locus_tag="VYP66_000682"
     CDS             complement(60625..61362)
                     /locus_tag="VYP66_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850278.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(61364..62248)
                     /locus_tag="VYP66_000683"
     CDS             complement(61364..62248)
                     /locus_tag="VYP66_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850279.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(62235..62429)
                     /locus_tag="VYP66_000684"
     CDS             complement(62235..62429)
                     /locus_tag="VYP66_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850280.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(62426..62632)
                     /locus_tag="VYP66_000685"
     CDS             complement(62426..62632)
                     /locus_tag="VYP66_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850281.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        18387 a        14154 c        11576 g        18757 t
ORIGIN      
        1 gaccacaatt actcaatacc gaatacccct gaatggtttc tttttcatgc accaatatat
       61 tataataatc ttcatccaat aataaggctg ataaactagc atcttggtca aaatgtaagg
      121 gaatttctcg accgtccttc tttaatggat attctggtaa gatactaaat agttcaatca
      181 tagaaggaaa ctcaggatta gttgttgtaa atcgaaaaag ctacgctttc tcatctttct
      241 gacttccttg atactctccc aattctaaaa aatgattcaa ggtagtataa aattccttat
      301 tttttacttc atcaatgatg accatatcat aatcttttgt tgtgcgactt ttaaatcctt
      361 gcgaatccaa tacgatagag gtagcagttc ccccaatcag aacataatag ttctgaaaat
      421 ccgcaaacat ttcttgaaaa ataactttcg tattagctgg catcatcttc tcccagatac
      481 tgtaatatca tattttctag tgcttcactc tcttcctcta tacgtgggtc atcatcatct
      541 tttaaggtca aataaagaga aatcggatct acaaattgtt tatcatgatt atttttaaaa
      601 tcattccaaa actcagatac aaaaggacga tatttccata tctctagcat ctttcatttt
      661 aaaacatgct gagaaagtgg caaggataac tgattgaatt ttctctgcca tatgacatag
      721 ctaatatttt catccgtttc agctaaaaaa gttgaatgcg acaaagcata agcaccacca
      781 tatagaaggt tagaaacaga ttttatctgc tttatatcgc catctggcaa taaaatccgt
      841 tttttgatgg gattaaataa acatgacacg gattttaaga ataattcttt ctttgacacc
      901 gtatatgtgt aaagcttatt ttgcttgttt aaccaatata aagctttaaa agtcctcaaa
      961 cacctataaa ttgttgagtt tggaagtcca gtgacttgtg aaagcaaatc aacatctact
     1021 actttttgac cttttgtcaa taaaaaggca atccacgtta attgttcgct aggtgttaat
     1081 tccttaggga cttcagtatc attcgcattg agtactagtc ccaatggagg gaagaagagg
     1141 tttcccttaa agtctacaaa cggaactcta gcttgaagta attgcttttt ttcactgtct
     1201 gataacttcg aaaacaccaa aacaacatcc atattggctt tttcacccat agtgcgagcc
     1261 tgagtaacaa atgaactcaa actccccctt ctcttttctt taatcaataa aaatgattcc
     1321 ttatgaaaag tcatttgagt atactcaaac ctttttacaa aactgattgg taaagtcaaa
     1381 gtcagttcct caatactgac atcaacataa aaggattgaa aaattgacat tatctttttg
     1441 acattcatgt tttttcctta ttctatcatt tttattatat tttatcattc ggtataataa
     1501 aatataagtt ttttgataaa ataaccaaaa actactcgct atcccctctc acattaccct
     1561 acatatcgtt tgacatgcga ctgatagttc aggaaaactt caaggagaac ttttctctca
     1621 tccactatgc aggacttact atttcacttc tactcctata ggctcaattt gacacttttc
     1681 tttttcgaat tgctcatatg cctcctgaat agtgagttcg atttatccaa atttattttt
     1741 gtctattttg atgaatactt ccacgaagat agtctgaaaa tgaatttgca ccaattttcc
     1801 ttctcttttt aagcatatta ttccagatat gattgccctc ttgttcagta ataaattacg
     1861 ctttaaacgc ttcaatcagt atatctcctg ttgtcatatg ttctaaagaa aattcttcta
     1921 catatgattt aacatctctt aggttattac ttcctaatat cccattatgc tttttcgcta
     1981 aggaaataga agccgcttct cccttaccaa taatcttgtt attatcatga tttcttgtta
     2041 aatctctata taatgcgtat tcttcagttc caatgtctat gctcacaatc tcagctgaac
     2101 ccttagctac caactgatct atcctagatt ttaaatgggg aattgtaggt atattgattt
     2161 catcatacac ctcttgtgga ataacaattt tacccgaata gagcttttct aaaagatgtt
     2221 cagtgccaac ccataaaaat actgaaatac aatctgcatc aataaataca cgactagtca
     2281 aacgacaact cccccctctt catctagccc atatacaata tcatatctga aagcatctag
     2341 taacagttcc tcatacttcc cttgcgaaat tctgttattt tctaaaagtt gttcagttga
     2401 attaatatat tatcctaata ccatttcctt tttactttct gacaaaggac gatataaact
     2461 tgtatcatag cctaatcttg aagctgtctc tataacacta atatccatat ttttaatttc
     2521 ttctgcatca aggtatccat cattcctcaa tctatataac atagctttat gactgatacc
     2581 ataaaactga cccaatttta taatatcttc tacttcaaga tgagttctat tggcattttc
     2641 tctgatttcc tcaaccatcc tatacagtga agatgggaaa attaaaaaat aagaagcaag
     2701 ctgatccgct tttctttcag tttcatctcc ttcaccaatc aagataagac tgactgaact
     2761 cttcttcacc tcatcataat aaagatgata cagttcatgt gctaaagaaa atctttacct
     2821 tcctaatgac atgtctgaat tgactgcaat gagactgaac tgagttcctt tataacagac
     2881 tccgctaata ttctttccga gtccataaaa taccagcgtc aaattttcta tcttttgtac
     2941 caatttaaaa atatctatcg gcgcttcacc atcagctccc aacttttttc taagatttga
     3001 agctttatta cttaaatcca ttcgtgatat tcctttcacc tttttccatt ttggcaatca
     3061 tgctttgatt caaagacaaa tataaagaca aatattcagc aatcttatct tgagtaagat
     3121 ttgaagatat tctaagttct tttattcttt ttccaacatc acatacattt atcatattca
     3181 tacacctctc ataaaaagaa tagcacactt ttgtcataat tttttaaata aaaaaattat
     3241 gacaaaacaa ggaagcaatt tattgatgct gcttaaaaat ctaaaattga tgagttccta
     3301 tcaaaaatcg tatcttcaac ctcaaaacag tacttaaagc tatccgactc ggtttacatt
     3361 gtcaaattta gattttattt gagcataact ttctagtttg ctttctgatt tttgtttaat
     3421 atagtagcaa acattgaagg aaatatctcc acaaaaaaac gcatactatt aagctttttc
     3481 aagacctaat aatatgcgct gttctgattt gaaagacatt ccattattat tttactgtaa
     3541 tcaagccatc tggctctact gtgaattctg gcttgtctgc cagtgttccg tctggtttga
     3601 ggtagtacca gcctgttccg tccgctgact ggataaaggc atttgatacc atggcgcctt
     3661 ctttagcgtc taagtagtac caagtgtcct tgtacttgac ccagcctgtc ttcatggcac
     3721 cttcttcgtt gaaatagtac cacttatcag cgattttctt ccagcctgta gccatttcgc
     3781 ctgagttgtc gaaccagtac cagttgccgt ctgtgtgctt cctccagcgg tctgcaagca
     3841 tatagcctga actgtcaaag tagtaccaag tgccattgat tttctcaaac ttgtcttttg
     3901 gataagagcc gtctgaatgt acgtaccagt agccagtgtc attcttctgc cagcctgttt
     3961 caatcgtcaa gccgttctca atatcatact taaactgctc acggctaatg ccccattttg
     4021 ccaagtaagg gtatggatcc acatggtctg agtggttgtt tggttggtta ttcgtgcaat
     4081 actcgtgcgt tttaattcca gctaaactcc ctgtatcaag cgttttcggc aaacctgctt
     4141 catctgctag attgcgtaag agttcgatat aaaggcggta gtccgtcatg aactcttctt
     4201 tagttgaatg gctttcaatc agttcaaccg ctgcataggt ctcagcattc caaccgcccc
     4261 caacgtccca ggcaccatta tcaacaggtc ctacctgcat gatgcaaccg ttcccaacaa
     4321 tgtgcgagaa aaaacctaat tctgggtctt tccgccagtg ataatccgct tcattctgta
     4381 cggttgaatg cggattccca gttgagtgtg cgtgtacttg cctatatggt tgcacgccga
     4441 cttgaggcaa atctgttctt aatttactca cattaatttc catattctac tccttatcaa
     4501 ttaaaacaac tcatttttta caatccagaa ccagaaactc ctttatttct accttacaaa
     4561 gaagacaatc ttagtcacga ttaggcttgt agatagaacc tcaaaacgca ctattttgac
     4621 actgtaaata ggactgacaa ggtctgcatt ctatctacaa taacacccca gactaaaaag
     4681 cttttcaaaa gtatattttt acagtctcta tatgtccttt tcataaatac tatactttat
     4741 tatatcatat aaaagaagtc aaaagtctgt taaactattt tcaacaccaa actaaagaag
     4801 agaacacaag ttttttcgat gttcactaga ggaaatggat tttattcagt aaatccaact
     4861 aggattgcac tttggttgcc aaaattgcct ttccttcttt tatcaaggga tgacggaata
     4921 gtgagaagta cagttgaact gtcatggcaa cccagataag aggttcacaa aggataacac
     4981 ccttatatcc tgcccaagga ataatcaaaa ccacaaaaac gatttttccg attagttcaa
     5041 taaagctaga aactagagga aggatcttct gccccaagcc ctgcaagcaa ttgcgataaa
     5101 tcaacaagag gctcaaaatg ggataaaagg ctgaactgat ttgcagatag agacttccat
     5161 tttctatcaa gtaaccatct gtcgaactag ccaagaagga aaccaaggct ggactggcaa
     5221 aaaagaggaa aatacaaaca aaaactgccc aggatatact taaacgactg ccgattcgaa
     5281 gaccttgaac aatgcggtca ggtcgcttag ctcctagatt ctgagaagca aaggtcgtca
     5341 ttgatgcaga aatagcggtc ataggaagaa gggcaaaggt cataatgcgt cgagctgccg
     5401 tctgggcact aataatcact gcaccaaatg tattaacaga aaactgtaaa atcacactgc
     5461 cgatagatac aattgaactc atcaagccca tagacaaacc ttgctccaag agatccgcgt
     5521 acaagctttt gtcccatttg aaatgtttaa actgtggcaa gagttctggc acacttttac
     5581 gaatataata aaagcagaga accgctgata aaccttgcga aataatggta gcaagtcctg
     5641 cggattgaac tcccagatgc aattgcgtaa taaaatagag atccagaacc acattaacca
     5701 aggcagagaa aatcagaaat cccagggctg ctagactgtc accaatagac cgcaacaagc
     5761 ctgcaaaaag attataagca aagctgacac ctacacaggt cacaatcata gaaatatatt
     5821 gataagattg aggaagaatt tctgcaggag tatctaagta ttgcaagaga ggatacaagc
     5881 caagaaagcc cagcaacata actagaatgc tcaaaagagc acctaaaatc caagtagctg
     5941 ctactgcttc cttgatttta gtgaaattcc gagccccata ataacgagca atgacaatcc
     6001 ccatgccatt gccaacacca agtgtaaaac ctacaatcag gtcaaaaatc gctgtcgtcg
     6061 ctcctactgc agccaaggat tcttgaccaa gaaatcgtcc aacaatcaag acatcagcag
     6121 tgttatagag ctgttgaaaa atatttgata gcaaaattgg aaaggtgaag cttaagagcg
     6181 agggaagaat cggaccatgt atcaggtcca ctgttcgttt tttattcata aagctattat
     6241 atcagctttc cagaggagcg acaagaaaca gcaaacttat atatagcgga atgaaataag
     6301 gaaagtcaaa tcgattttta acaatgtttt agaagtagat atgtactatt ctagtttcga
     6361 tctattatag ttggttgagt ttggaatagt acgctgtagc tgctaaaaca tttctagaaa
     6421 ttaatttgac tttcctaata gagttgttca tatcttattt caagctacta tatataatct
     6481 aaaaacttga atcaaaaatc gaaaaagtag cggatttctc cactgcttta acagcttatt
     6541 cttcaatttc gatttcaagt tcatcgccta agtcaagcgt aacttcttca ttcactgctt
     6601 cttctttctt tggctcatct tttttgtttt cagtatcttg ttctgaaact tcttctccat
     6661 caatcaagcc aaatttagaa cggacttgct tatcaatttc atcaaagatt tctgggtgct
     6721 ctgccaagta tttcttagca ttctcagaac cttgcccaat tttttcatct ttgtaagaat
     6781 accaagcccc tgcttttttg ataatatcca aatcgcttgc aatcttcaaa agctcaccag
     6841 tcttagaaat tccttctccg tacataattt caactacggc ttccttaaac ggtggagcta
     6901 ccttattttt tacaacctta atcttagttt ctttaccgac attggtttct ttttggtcac
     6961 cagttccctt aatttgtgta ttaccacgaa catccaagcg gactgaagca tagaatttca
     7021 aagcacgtcc acccggtgtt gtttctggat ttccaaacat cactccaact ttttcacgca
     7081 attggttgat aaaaatggca attgttttgg ttttattgat agaggcgcca agtttacgca
     7141 tggcctggct catcatacga gcctgcaaac caacatggct atctccgata tctccatcaa
     7201 tttccgcacg aggaacaagg gcagcaactg agtcgactac gacaagatca actgcacctg
     7261 agtcaatcaa ttttcccgca atctcaagac cttgctctcc tgagtctggt tgagacaaga
     7321 gcaattcgtc aatattgaca ccaagggccg cagcataagc tggatcaagg gcatgttccg
     7381 catcgataaa ggcagcaatc ccaccttctt tttgcgcttg tgcaactgca tgaagggcaa
     7441 ccgttgtctt accagatgac tctgggccat agatttcgat gatacgtccc ttaggataac
     7501 cacctgagcc aagggcaatg tcaagagcta aagaacctga gctcatcact tgcacctttt
     7561 gctctgcacg ttcacccaaa cgcatgattg atcctttacc aaagtctttc tcaatcaatt
     7621 taagagcatc attcaaggcc ttttcacgtt ctgccccaaa tttttttgaa atttcttcta
     7681 atttttttgg ttttttcgcc attctattct cctacattct aatgatcctc agacctatct
     7741 actattatat caaaagttag tcacttaata aagccttgcg aactaggtta aaggcatgca
     7801 taaccgcaat gtgacgtaca tctgctcggc ttctgcctcc aatattaacc ttgataacct
     7861 cagttccttg atcttgcgcc aagcctatga agactgtccc aactgggttt ccttctaggc
     7921 tatctggtcc tgccactcca gtcaaactaa ttccaaaatc agactgggtc ttgcttcgtg
     7981 cctgctcagc catcttctga gctgtaaatt cagacaccac accatgttct tccaaattct
     8041 tggcaggaat atccaacatc cttgattttt cctccaagct ataggtcaca aaaccgccct
     8101 taaatatact tgaaactcca gaaaaattcg ccacggtagc ttggaaaaga cctgccgtca
     8161 aactctctgc agccgcgatg gttttccctt gccttttcag ttcttctacc acaatgctgg
     8221 ctaaactagt ttcttcccca taaccatagc aaaagtctcg taaagaaatt ccttcgaaag
     8281 tctggcagtc caagatttga ttttccaaga tatccagcgc ttgattcgcc tcttcttgac
     8341 tgctagcctt tgttgacaga cgtagagtga cttctcctgt cttggcataa ggggccaagg
     8401 taggatcgat ctgattatca attaaatcag ccaaaatcgt aaccaactgg ctctcgccaa
     8461 tcccaaagaa acgaagaact cgggaataca gcttgctccc tgtcatcaac ttgggtagaa
     8521 gttggtttaa gaccatgggt ttcaattcac ttggcggacc tggaaggacg acataggtca
     8581 ctccgtctac ttctaatttt cctccaacag ccagtcctgt ttcgtttggc agtggaatcg
     8641 ctccttctac aatttgagct tgtctttcgt tattcggtgt tcgggcatag tctggtcgca
     8701 gggtaaaaaa gatatccaac ttctcctgag cctgaggatc aaagactaat gctttcccta
     8761 aaaatttagc tagggtttgt ttggttaggt cgtcctcagt tggccccaaa ccgcctgtca
     8821 aaatcaccag actgctacgt tgactggcaa tctcaagcaa agacaagaga cgaacttcat
     8881 tgtctcctac agccgtctga aaatatacat ctaccccaat ctcagctagt ttttccgaca
     8941 aaaactgggc attggtgttg acaatctgcc ctgtcaaaat ctctgttcca acagcaatga
     9001 tttctgcttt catgtttcct cctacctatc tattcgtatt tttttgaaaa aatcgcagga
     9061 attttcctac gattgatttt tttatttgta tcaaaagtta attatcttca tcaccaacag
     9121 gtgctctgcc aaataaatct tcaaataaaa ccgcattggt ttcaagctga gtaacttctt
     9181 cttgtcccaa agaacgtcgg agtagatttt gcatttccaa catatgtgct ctcgaaacaa
     9241 tctggtaaga aacaccttga agtatctctc cttcaccctg caactgctga gtttcaatgg
     9301 ttttaaatga atctttatag cctagcaagt tagggatact ttttgcagac aaatcaatat
     9361 tggtctgcat attgtcactc aaagctttta gaatctcttg ataatgacca atgctattta
     9421 aactgagagc tttttccatg actttttgaa taacttcacg ttgacgtttt tgacgaccat
     9481 aatccccctc aggatcttgg taacgcattc gtgcatagac tagggcttct tctcccccaa
     9541 tatgttgctc cccaacaccg atagaaatag tattaaattc ttcttggtca ctgatagaaa
     9601 ttgggaaacc taggatatta ttgactgtaa tacctcctac tgcatccact agtttttgca
     9661 atcctctcat attgaccatc acatagcgat caatatggat attcatcatt ttttgaatgg
     9721 tttctatagc aagctctgct ccaccatctg catatgctga gttcagtttc gcttcatgag
     9781 cctgaccatt ccctgattca atgcgcgtca gaatatcccg ctctaaactc atcattgttg
     9841 tttttttcgt tttaggattc actgtcatca agatcatgct atcacttcta ccgacccaag
     9901 tttcagttcg ttcaacattt ccggtgtcca ctcccattaa cagaatggtt agaggttcag
     9961 tcgcttcaat aaccttggtt tcttcgccga tttttttata ggttttagct aaggtttctg
    10021 tcccttgttg ataaatagta taagcaaaaa cacctactcc tactacagtt acagaaagta
    10081 aagctagcac cattccaata atttttttaa ccatatttct actaacctat cagtttaccc
    10141 atcaagtaaa catcgataaa tttcccttct tctatatatg ccccacgctc ttggctacct
    10201 tcaatgacaa agccatgctt ttgataaaga tggactgctg cttgattacg agtttggaca
    10261 gtcagttgga gacgacgcag aatgccactt gcttgtgccc actctatcgc ttcttctagc
    10321 aacaaacttc ccaagccatt attccaatat ctttttccaa tcacaatgaa gagatctcca
    10381 atatgacgga ctctcttacg ctggtcagct gtaatattta caataccagc aattttgcca
    10441 tttaagaatg caagtaaggt tatctgattg tccgaactag cttgcttgtt gaggaatatt
    10501 tccatctcct cactagtcaa gagaatacca tctccgtcta ggctggtaaa gtctgtctcc
    10561 aaactcacac gatttaaaaa ggccactaat tcagctgcat ctttgggctc tgcttcccta
    10621 atgagcaatt catactccat attgaagctc ctctaacaat ttctcagcac gcaaaccctt
    10681 tgcctgaaaa tttaaacggc gtccatctgc ttcttttaga atttccaatt ctaaataagc
    10741 atctggcaag gcatctccta agagatttcc ccactcaata acagtcacgc caccaccaaa
    10801 gataaactca tccaagtcga tagaatcagc atctccttca atacgataaa catctaggtg
    10861 ataaagtgga agtcgacctt catactctct cacgatagta taggtgggac ttttaatcat
    10921 ttgagaaatc tgtaatcctt ttgcaagtcc tttagtaaag gtcgttttac ctgcacccag
    10981 ttctccagtt aagattaaaa catcattctt tgctaataga tggcccaaac tctcccctaa
    11041 ggcttgcaac tcttcttcat tttttgtgta catactctta ttataccaaa aacttttctt
    11101 ttgtgtctat tttcctacta aacttatcat cataacatcc ataaaaaaca ggctttctct
    11161 aaaagaaaat gagcgtaaca atgaccaata caagatctcg gaaaatatga ccataaaagg
    11221 aaacttcctt cttaaccgaa tttgggacaa gataggctgc aaaaaacaag cccagtccaa
    11281 tataaatcag aagtgagaca atggtcattg gatttcttaa gaaaagaagt gttgctaaaa
    11341 tagtcaccaa cactgtcttt tttctgtcta gcatagcaag aaaatcgcgc acgtattttt
    11401 tcaagggtaa aaaaatcagc aaatctagcc caaataggaa aaagaaggat ggcaataaaa
    11461 agtcaactaa ttcttgctgc agcgtatttt tgatgaacaa gttatctgac aaaacaagaa
    11521 cagctcctaa caaattaatt aagagtaaca tactgtaaaa aagcttcacc gacttcttac
    11581 tggctaggac actatggact tcttgcttac gggtataaag ataatttact ccagcacaga
    11641 ttcctgaaac gaaaaccatg cttccgatga aaaaagctgt actttgttta aaggacaaga
    11701 tgcattcctt ccataggaaa cagctactca aactgatttg aattaaagct aacaaaaata
    11761 agattctcat tgatttcatc ttctctctcc cttcctacca atcattatac taggagaaaa
    11821 gagagaactg tttctaatct tctcaaatgt ctctttaaga cgctaaacaa acactagaga
    11881 ctaatactca atgaaaatca aagatcaaac taggtagcta gccacaggtt gctcaaaaca
    11941 gtgttttgag attgcagata gagctgacgt gatttgaaga gattttcgaa gaatatagat
    12001 ttgaaatcat gaaaatccgt caaacgggtg gttgttttgt ctcgcacctc acggagcgag
    12061 acggactcag agtcacataa ttataaggct gatagtatta atctaactat cagccttaca
    12121 ggttatttaa cgtttcagaa aaactataat gtcaagatta actaaacagt atctagttcc
    12181 ttcaaataat tttctatctt catcagcatt aaaggattgt tataaatctt gcatagctct
    12241 cttgcttcta tataataatt tttgacttgt tctctgtcta gaaatttggc tccagcattt
    12301 cctacaagaa taagtagagg agccaattgg tagcttgtct gtctttgttt acagagttca
    12361 atcgtttcaa gagcttcttg gatggcttca ttatattttt cctttgatac taggtagtga
    12421 gcgtagttgt aacgaactct gatgtagcca aataaaaact cttgatggtc caaatttttt
    12481 gtctgataca actctattaa atgagagtag tttgcctcat attcttgttc acgacccact
    12541 aaggaataga aattagatag agtattcaac gcctttaaat aaatcagagt atttgaagag
    12601 acttttaata atatattttc caatgaagaa attgcctcac acttactgtc atattgatag
    12661 aagtcaataa tagctttaat ccattcaagg taagttcggt cttctagtgt tagaaaagta
    12721 cttcgttcaa tctctattct ataaatatat tccaaatcgt cataatttct atcgtctaat
    12781 agtcgagcag acaattgctt gaaattagag aggttagatt taatttcaat ttgttcatta
    12841 aaaaaataat ctaatggtac ttcaagtcgt tgagagagtt tgaacaaaag gtctgcggag
    12901 ggaatgaaat gccctctctc aattttacta atctggcttt gttcacaaat tccttctgca
    12961 agagtttgtt gggagagtct caactctttt cttttcaatc tgaatttctc tgcgagtgta
    13021 ttcattaaag ataataaacc ttcctatttg cttaattgca ttataaaatt tttagttcaa
    13081 aatagcaagt taaaggaata aataattctt tatggtaata aactaaaaaa agtcaaaaat
    13141 tacataaaaa tgcttgaccg aataatatat atatattaaa ataaaaacaa ggaaaaagaa
    13201 aagggtttca cgaatgaaga aaaatcgtgg aattcaaaaa ttagctatat tagtattact
    13261 aggtgttttt atgtttagta acacaattcc ttaccaacag tttattcaga agaatagaca
    13321 attggagatt cgagtgcaat cacaaaagaa gtccaatggt cttgatgttg ggaaggctga
    13381 ttgatttcgt attactttaa aattcaacta tttagagaaa ggtattctga tgagagcttg
    13441 taacaatacc agatagatat aagaatggag atgtttgata aaatgctttc atagctaacc
    13501 aactgttgaa aattatgagt tacaaaatct aaagtattta agattggttt ataaaattag
    13561 gtctctgcct gtagaaagga acgtgcagtt agaaaggagg aaaaaatagg atactataat
    13621 tcagactgag atttctaatt aaaatatgta gttgcatttc gctcattttc ataatatttc
    13681 attcagagga gtaataatat gttaaaattt agatttgatg cgggatggta aagaataatt
    13741 gaagaagatt cttttatcaa tagtttagta agcttgttag tttatagagg gcaggggtat
    13801 ttctgccctc tgttttagaa taaggaatgc actatgaaaa aattatttat actcatatcc
    13861 aacctgcttg ctagtttgtt ctttgtttgg gtatttacca tttggactga tacatatgtc
    13921 tcccattatt accccaacgt tgttgtacgt gattcttccc ctgaaacaac ttttcagcat
    13981 gttgctacac gcttggaaaa actagcagaa gaaacagata gctttattgc gattcaacac
    14041 caagatccta actcagaagg tactacagtt ttttcttata cgacctttgg ggacggaaag
    14101 ttgcctgatg ggcttcagga aaaaaatcta gaagatgctc aaagtagtag tgttgaaaca
    14161 aactattttg tattcgatgg acacctagat attcacttgc taagggaaga gctaagtcaa
    14221 cttggcttga ctaacatgca cctgacaatt ccatctaaac tatctacgtt aatggctatc
    14281 tttagtaacg gatttcagtt aatcagtcta ttgattttca tcttaacctt tgtagcactg
    14341 actttaatta gtcaaattag ccaattacgg tcatcgggca ttcgcctcat ttcaggagag
    14401 aaacggtggt ccattttcct tagaccagtt ggtgaggatt tgaaagcgat agctgttggt
    14461 ttcagtttag ctggcgtgct cgccattctt atgcaaaaaa ttctgtcgct tccaacgcaa
    14521 tccctaatga ccacaggaga aggcttgctc agttataatc tcatcttgtt gtcgatctcc
    14581 ctgtttttca ctcaactctt cgcagttggg ataaaaaaga tacacctgat gcagattata
    14641 aaagggcaag tgcctgtcag aggaatcatt agtttgattt taatcggtca actattagcg
    14701 attattattg taacgctggg aatagggagt agcttaaagt attcccaagc ctggcaacag
    14761 catcggattg gacaagaggt ttggagtcag gaaaggcaac tgattaccct atcaatcagc
    14821 cgtgaaggaa cgagtcctgg ttttgatgaa caagctcaaa ggaaactcag aacttggtat
    14881 caattgatgg atctggctgt ttcagaacaa aaggctttct tatctagaca ccagttaatt
    14941 gaccgtactt tgcaaaatgg catggcttcc tccaaaaact tgataacctc tacagaatgg
    15001 cacgattaca acccgaatgg caatgtcctt atcgtcacac cgcaatactt ggagcgtcaa
    15061 aacattcctg tagatacaac tattgagcaa aagatgaatc accttgatgt aggggagttt
    15121 gtcttattgc tgcctgaaca cctccgttca gaggaagaac attataaatc tgtttttgaa
    15181 gacgacttaa ccagtcgcat gtctagtcaa gatgaacgac agcaaatgac tgctacggta
    15241 ggttatttag aatcaggtca ggatcgtttt gtgtataata cgacccctat ttcttaccag
    15301 cagtttttga aagatccaat catcattgtt ataacacccc aatcaactgg tccacagtcc
    15361 attttgtttt ggatagacgc agtacagaac tacgttctct ttaatcaatt gtctgatgcc
    15421 caggagctta tccagagaca aggcattgaa aattgggtct cagaaatgca aacaggttac
    15481 cacaactaca tcacattatt ggataatatc cagagggaac gttgggtaat gctagcagga
    15541 gctgtgcttg ggattgcaac ttcaatcttg ttgtttaaca ctatgaatag gctctacttt
    15601 gaagaattta gacgtgccat ttttatcaaa cgcattgcag gtctcaggtt cttagaaatc
    15661 catcgcactt atctctttgc tcaactgggt gtgtttttac tgggatttgt tgcgagtgta
    15721 tttcttcagg tagagatagg agttgctttc ttagtcttgt tactctttac tggtctatct
    15781 cttttacagt tacatgtcca aatgcagaaa gaaaacaaga tgtccattct tgttttgaag
    15841 ggaggttaat atgattgaac ttaaacaggt gagtaaatct tttggagaac gagagttatt
    15901 ttcgaatctt tcaatgacat ttgaggctgg aaaagtctat gccttaattg gttcaagtgg
    15961 tagcggaaaa acaaccttga tgaacatgat tgggaaatta gaaccttatg atgggacgat
    16021 tttttaccga ggtaaagact tggccaatta taaatcgagt gattttttcc gtcacgaatt
    16081 gggctacctc ttccagaact ttggcttaat tgaaaaccaa agtattgaag aaaaccttaa
    16141 gctaggtctc attggtcaaa agttgagtcg gtcggaacag cggttgaggc agaagcaggc
    16201 tttagaacag gtcggcctgg cttatcttga cctagataag cgcatctttg agttatcggg
    16261 cggagaatcg caacgggttg ccttggcaaa aattatctta aagaatccac cctttattct
    16321 ggcagatgag ccaacagctt caatagaccc agcaacctct cagttgatta tggagatttt
    16381 gctatctctt cgagatgata ataggctaat cattatcgca acacataatc cggcaatttg
    16441 ggagatggct gatgaagtgt tcacgatgga tcatctgaaa taaaaatcct tgtttttaat
    16501 tgcacgatga gttactgaaa tattatcatg aatcaagaat tggagttaat ttagaattgt
    16561 actttattaa tattgaggta actttttctt gataaaggaa gaaataatgg agaggaagtt
    16621 agaatgaaaa aattcgacaa ttatattatt gagaagcctt gcgattctaa ttcagataaa
    16681 ctgcaaaaaa tcttaataat tgaaagtttg gtagatgata ttttgcaatt ttctctcaga
    16741 atcaataata gtgtaggaga gattttcctc ctacaaccgt tttaaaagaa aactatcttt
    16801 attccatgtt attttgagga agatattgtg aaagtcaaag atgatgataa agttgagtgg
    16861 aatttgttag aatttcaaaa atttagagca tttttggctt agtaatctgt gttgaaggct
    16921 caaaacctat ggtaaaaaag tcgctttgaa aacgtattgc ctccaaagat ttagttaaat
    16981 aatgatttaa cacaaaaaga aattattgaa gttctggaaa gatgttgttt cagtattgag
    17041 aaaaggtggg aaaaacttgc gattttcaca gagaaaggaa gaaaaagtat agaaatatag
    17101 tcaattgaaa caagaacagg ataaaagaac cttttgtgcc atatttttct cctttcgctt
    17161 tacaattggc ttgaacacct ttattgtatc gcgtttggag tttttttggt ataaccttcg
    17221 acgcgcaccc gcatagcggg tgtttttttg tctcgcacct aacggagcga gacgaactaa
    17281 tagtcactta atcaaaaaac gcaccatatc aaaaactaaa aagtttgata tcatgcgtca
    17341 tgtcttaaac taattgacta tactttctat tcaaatgagc ttttaaccaa ttgattgagc
    17401 caatccactc ttaaaaccaa agagcaattt ctcgcttagc tgactcttct gaatctgaac
    17461 catgtacaac attttggata acctcatttt ctccagcagc ttttgcaaag tcacctcgaa
    17521 tagtgcctgg taaagcttct tctggacgag ttgcacccat catggtccgc caagtttcga
    17581 ttactttggg accagaaatg acacccacaa gaactggacc tgaagtcatg aattcacgaa
    17641 tcggtaggta aaaactctga ccaaccaagt cctgatagtg ctggtcaatc aactcttctg
    17701 aaacctgtga acgaaactcc aatttttcga ttgtaaatcc acgttgttcg atgcgcttta
    17761 acacttcacc cactagccct ctttttacac catctggttt gatgataaag aatgtttgtt
    17821 ccatacccgt ctcctttgtc agcttctttc ttttatttta ccacatttcg tggaaaaatg
    17881 gagaaagttt tcagaagaga gaatgagaga acccgagggt tctctcattc tctcttattc
    17941 tactgtttct tccacagttt caacggcagt atccacaact acttctgttg tttcttcatt
    18001 tccttcttcc tctactggag gattaaggta ttcttcttcg ttgacagcat gtggttcaag
    18061 gttacggtaa cgggccatac cagtaccagc tgggatgatc ttaccgatga taacattttc
    18121 tttaagtcca aggagatggt ctttcttacc acggatagct gcgtcagtaa ggacacgagt
    18181 tgtttcttgg aaggaagctg ctgacaagaa actgtttgtt tcaagtgagg ctttggtaat
    18241 tcccataagg actgggcgac ctgtcgctgg aactccacct gcgataagga catctttgtt
    18301 ggcatctgta aagtcattga tatccatgag ggtacccatg agaagatctg tatcacctgg
    18361 atccatgaca cggactttac ggatcatttg acgaaccatt acctcgatgt gtttgtcacc
    18421 gatttctacc ccttggctac ggtaaacttt ttgtacttca ccgagaaggt acgtttcaac
    18481 tgacaagaca tcacgaactg caaggagacg ttttggttgg atagaacctt ctgtcagagc
    18541 agcaccacgc gctacttggc ccccaacttc gacacgcata cgagctgtaa atggaacgac
    18601 atattcacct tcgccagttt cacccttaac aaagactttc ttggtacgag ttgatgcatc
    18661 ttcttcgata gcagtaactt gtcctttaac ctctgtgata accgcttccc ctttaggatt
    18721 acgggcttca aagatttctt ggacacgagg aagaccctga gtgatatcgg tatttgaggc
    18781 aaccccacct gtgtggaagg tacgcattgt aagctgtgta ccaggttccc cgatagattg
    18841 ggcagcaatt gtaccaactg cttcaccaac ttcaaccgca tcaccagtcg ccaagtttat
    18901 accgtaacag tgacggcaga caccgtgacg agtgttacat gtaaatacag aacggatagt
    18961 cacttcttcc acaccagcat tgacaatttc acgcgccttg tcttctgtaa tcaattcatt
    19021 tggaccaata atcactgcac cagtttctgg atgtttaaca gttttcttag tgtaacgacc
    19081 gttgagacgc tcttcgagag actcgatcat ctcttttcct tctgcgatag aacggatcaa
    19141 gagaccacgg tcagttccac agtcgtcctc acggatgata acgtcttggg caacgtcgac
    19201 caaacgacga gtcaagtaac ctgagtcggc tgtcttaagg gccgtatcgg tcataccttt
    19261 acgagcaccg tgagttgaga agaacatttc caataccgac aaaccttcgc ggaagtttga
    19321 aaggattggc aattccatga tacgtccatt cggagcagcc atcagaccac gcataccggc
    19381 aagctgtgag aagtttgaga tgttaccacg ggctccagag tccatcatca taacgattgg
    19441 gttcttagga tcttggttgg caatcaagcg tttctcaagt ttttcacggg cagcacgcca
    19501 ttcagctgta acagcattgt aacgctcgtc gtctgtgatc ataccacgac ggaattgttt
    19561 ggtgatttgt tcgacacgtt tgtgtgattc ttcaatgatt tcagtcttgt catcaacgac
    19621 tgggatatcg gcaataccca ctgtcaatcc tgcaagagtt gagtggtggt aaccgaggtt
    19681 cttcatgcgg tcaagtaggg cagaagtttc tgtcgtacgg aaacgtttga agatttcagc
    19741 gatgatattt ccaaggtttt tcttcttgaa tggagggttg agctcaagat tgctgatagc
    19801 ttccttgata tctccaccaa gtggcaagaa gtatttagct ggaacacctt ctgtcaagtt
    19861 ggcattgttt ggttcttgca agtatggtag cccctctggc atgatatcgt tgaagagaat
    19921 tttaccaact gttgtaagca agaccttatg tctttgctct tctgtccaag gcttgttgag
    19981 gctgtctgtt gcgataccaa cacgtgagtg gaggtgaaca taaccattgc ggtaagccat
    20041 aaccgcttcg tcacggtctt tgaagaccat tccttcacct tcgcgaccag cttcttccat
    20101 ggtcaagtag tagttaccca aaaccatgtc ctgagatgga gtaactaccg gtttcccatc
    20161 tttcgggttc aagatgtgct cagcagctag catgaggata cgagcttctg cttgtgcttc
    20221 ttctgaaagt ggtacgtgga tggccatttg gtccccgtca aagtcagcat tgtaggcttc
    20281 acagacaagt gggtgcaagc gaagagcctt accatcaatt aagactggct cgaaggcttg
    20341 gatacccaaa cggtgaaggg tcggtgcgcg gttcaaaagc actgggtgtt ctttaatcac
    20401 ttcttcaagg atatcccaga tacgctcatc tccgcgttcc accaagcgtt tagctgcttt
    20461 gacgttttgc acgatatcac gggcaacgat ttcacgcatg acaaatggtt taaagagttc
    20521 aatcgccatt tcacgtggca caccacattg gtacatctta agagttggac caacggcgat
    20581 aacggaacgt cctgagaagt caacacgttt accgagcaag ttttgacgga agcgtccttg
    20641 tttaccttta agcatgtggc tcaatgattt caatggacgg ctacctggtc ctgtgattgg
    20701 acgaccacga cgaccattgt caatcaaagc gtcaactgct tcttgaagca tacgcttctc
    20761 attttgaacg atgatacctg gtgcatttaa ctcaagcaaa cgagccaaac ggttgttacg
    20821 gttgataaca cggcggtaaa ggtcattcaa gtcagatgag gcaaaacggc caccatccaa
    20881 ctgcaacatt ggacgaagat ctggtgggat aaccggaagg atgttaagaa tcatccattc
    20941 aggtttgttt ccagacttgt aaaaggcatc caaaacatcc aaacgacgga tggctttgac
    21001 acgcttttgt ccagtagctg ttttcaattc ttctttgagt tcagcaattt ctttttcaag
    21061 atctacttgc ttcaaaaggt cttggatggc ttccgcaccc atcttggcaa caaatgaacc
    21121 ataaccatat tcacgcaagc gctctcggta ttcgcgctct gtcatgatag acttgtgctc
    21181 aagtggtgta tccttaggat caatcaccac ataagccgca aagtagataa cttcctcgag
    21241 ggcacgaggg ctcatatcaa gggtcaagcc catacggctt ggaatcccct tgaagtacca
    21301 gatgtgagat acaggagctt tcaattcgat atgtcccata cgctcacgac gaactttcgt
    21361 acgcgttact tcaaccccac agcggtcaca aacaattcct ctgtaacgaa tgcgtttgta
    21421 cttaccacaa gcacattccc agtcttttgt aggaccaaag atcacttcat caaagagtcc
    21481 ttcacgttct ggtttcaagg tacgataatt gattgtttca ggttttttga cttctccata
    21541 agaccatgaa cggactttac ttggagaagc tagggtgatt tgcatacttt taaaacgatt
    21601 tacatcaacc actatttctt ccctttctat tctaagtgaa ctgcttattc ttgttcagca
    21661 gcttcttctg ttgcttccgc ttttgttgct ttctcagctt cttcagcttc aaaggctgct
    21721 ttagcctctt gggctgcttt ttcgcgggct ttttcaaggt catctacgtg gatgacatct
    21781 tcgtccattc cttcatccaa gtcgcgaagt tccacttctt ggtcatcttc gtctaggaca
    21841 cgcatgtcaa gaccaagaga ttgcaattct ttgacaagaa ctcggaagga ttctggaaca
    21901 cctggttttg gaattggttt gccttttgta atagcttcat aggctttcaa acgtccgttg
    21961 atatcgtccg acttgtaagt caagatttct tgaaggacat ttgacgcacc gtaggcttca
    22021 agagcccaaa cctccatctc accgaaacgt tgtccaccaa actgagcctt acctccgagt
    22081 ggttgttggg taacagttga gtatggtccg actgaacgcg cgtgcaattt atcatcaacc
    22141 atgtggtgga gtttgatcat gtacatgact ccgacagaaa cacggttatc aaacggttca
    22201 ccagtacgtc catcgtaaag gatcgttttg gcatcgctat ccatacctgc ttctttaaca
    22261 gttgaccaaa gatcttcaga acttgctcca tcaaagactg gtgtagcgat gtgaatacca
    22321 agagtacgag ctgccatacc aaggtgaagc tccataacct gaccgatatt catacgtgat
    22381 ggtaccccaa gtgggttcaa catgatgtcg actggagttc cgtctggaag gtaaggcatg
    22441 tcttctacag gaacgatacg agagacaacc cctttgtttc cgtgacgtcc ggccatttta
    22501 tctccgacct taatcttacg tttttgagcg atgtaaacac gaaccaacat gttaacacct
    22561 gattgcaact catctccatt tacacgtgta aagatcttaa catcacgaac gacaccatcg
    22621 gcaccgtgtg gtacacgaag agaagtatca cgcacttcac gagacttgtc tccaaagata
    22681 gcgtgcaaga gacgttcttc agctgaaaga tctttctcac ccttaggtgt tactttacct
    22741 acaagaatat caccttcttt aacctcagca ccaatacgga taatccccat ttcgtcaagg
    22801 tctttgaggg catcttcacc aacgtttgga atttcgcgag tgatttcttc aggcccaagc
    22861 tttgtatcgc gcgtttctga ttcgtattct tcaaggtgaa cagatgtgta gacatcgtcc
    22921 ttcaccaagc gttcgctcat gataacggca tcctcgaagt tgtaaccttc ccaagtcatg
    22981 taggcaacga ttgggttttg tccaagcgcc atttctccat tttccataga aggtccgtca
    23041 gcgatgaaat cgcctttttc aacgacatca ccaactttta cgagagtgcg ttggttgtaa
    23101 gcagtacctg agtttgaacg acggaatttt tggatgtggt aaacatccaa tgaaccatct
    23161 tcacgacgaa cttctacctt gtcagcatct gcgtaagtaa ctttaccatc atactgagca
    23221 atcacagccg caccagaatc gtgggctgct tggtattcca taccagtacc aacgtaaggt
    23281 gcctgaggat taatcaatgg cacagcctga cgttgcatat tggctcccat gagggcacgg
    23341 ttggagtcat cgttttccaa gaaaggaata catgctgtcg caacggcaac tacctgtttt
    23401 ggtgaaacgt ccatgtagtc aacaatatta gctggatact cttggttgac cccttggtga
    23461 cgtcccatga caatcttctc agcaaaggtt ccatcttcat tcagacgaga gttagcctga
    23521 gctacagtat attcatcttc ttcatcagct gtcaaccaaa caatttcgtt cgtgacaaca
    23581 cctgtttcac ggtcaacctt acggtatggt gtttgaacaa aaccatattt gttcaagtgt
    23641 ccataagatg acaagttatt gatcaaaccg atgttaggtc cttcaggtgt ctcgattgga
    23701 cacatacgac catagtgagt gtagtgcacg tcacgtactt catatccagc acggtcacga
    23761 gtcaaaccac caggtcctaa ggctgacaaa cggcgtttgt gagacaactc agaaagcggg
    23821 ttgtgttggt ccatgaactg tgacaactgt gatgaaccaa agaattcttt aactgcagct
    23881 gttacaggac ggatattgat aatttgttgt ggtgtcaaga cttcattgtc ctgaacagac
    23941 atacgttcac ggacattacg ttccatacga gaaagtccca aacgtacttg gttggcaagc
    24001 aattcaccaa ccgcacggat acgacgattt ccaaggtggt cgatatcatc tacacggcca
    24061 agtccttcag ccaagttgag gaagtagctc atctcagcaa ggatatctgc aggagtcacc
    24121 gtacgaacct tgtcatctgg gttagcatta ccaatgatcg ttacgacgcg atctggatca
    24181 gttggagcaa taaccttgaa tttttgaaga acaacaggct cagtcacaac ggctgcatcg
    24241 tttgggatgt agacaatctt gttcaagtcg ccatccaaat ggctttcaat gctttcaatc
    24301 acgctacgag tcataatcgt accagcttct accaagattt ctccagtttc agggtctacc
    24361 aatggctctg caatggtttg gttgagcaaa cgtgttttaa cattgagttt tttattgatt
    24421 ttgtaacgac caactgctgc caagtcataa cgacgtgggt caaagaagcg agctacaagc
    24481 aagctacgtg agctttcagc cgtcttaggc tcacctggac gaaggcgttc gtaaatttct
    24541 ttcaaggctt cgtctgtacg agagtccatt ggattcttgt ggatatcttt ttcaacagtg
    24601 ttgcgaacca attcgctgtc accaaagata tcaaagattt catcatcacc tgagaaacca
    24661 agagcacgaa ccaaggttgt aaatggaatc ttacgagtac ggtcgatacg agtgtaggtg
    24721 atatcttttg agtcgctttc aagttccaac caagctccac ggttagggat aacagttgaa
    24781 ccatagccca ccttaccatt tttgtctact ttgtcgttaa agtaaacacc tggtgagcgg
    24841 accaactgag aaacgataat acgttcacca ccattgatga tgaaagtacc catttctgtc
    24901 atgattggga aatcaccaaa gaaaacttct tgggtcttga tttcgcttgt ttctttattg
    24961 atcaaacgga aggttacaaa aattggtgct gagtagctag catcgtggat acgagcttct
    25021 tctagcgtat attttggttc cttgatttca tatccaacaa attccaactc cattgtgtct
    25081 gtgaagtttg aaattggcaa tacatcttca aacacttcct taagaccgtg gtctaggaaa
    25141 gctttgaatg agtcagtttg aatttcaatc aaatttggta agtcaagaac ttctttgatt
    25201 cttgaaaaac tacgacgggt acgatgtttc ccgtattgaa cgtcatgtcc tgccaagatg
    25261 attctccttt gtaaataagt tccaagcctt gtcaatcagg cttttctaat cgtcatatgg
    25321 ttgtaaaccc cttatcaccg tgtcctcttg atgaattttc agaatcttta agcctctgtt
    25381 acaaatgctc aaaatcttga aaaaaagcac aaaaagagca gctaaatctg actttttcag
    25441 aagatttaac tgctgtgagc cttgtctgga caatatttca gacaaaacct acgacaaatg
    25501 attacccata ttatacccta tttagctaga tttttcaagg ggtttcagta ggtttttggt
    25561 aatttttttc ccatagaaaa cttggcatca cattcgaatc acgctatggt acaaaaaact
    25621 gaaaaaacta ttgactgaaa atcattttca aggtataata ataaacgtta aggcggtata
    25681 gccaagtggt aaggcacggc tctgcaaaag cttgatcgtc ggttcaaatc cgtctaccgc
    25741 cttctataac ttgatttatc aggtttcaaa tgaacagaaa gcccaatttg aagggctttt
    25801 tttattttcc ctcgaataaa tacgtataac tttaaaaact tttggagcga gtttgtggca
    25861 gagttctttc catggcataa ttcccttttg aaatcaattg aaaaaagctt cgtcacgcct
    25921 ggtgacaaaa gcctctagtt tattctgttt cttcttctat ttcgacttct gtgatttgga
    25981 cttttacctt ggtaacacgt ccattcttca ctttatcatt ggttaagata aactgtttgt
    26041 tttggctgac caattcatag ctgagtttct cagtcgttgg aatggttccc actcctgtca
    26101 aataataacc agcgatggta tcaacgtcat cactttccag ttcaacatca aagtaattat
    26161 tgaaatcatt gagggtcata gttccttgaa caatgtaggt atcctcgcca atctgatgaa
    26221 catctattgc tgctttatcc gtttcatcat caatttcacc aacaatttcc tctaagaggt
    26281 cttccaaagt cactaaacca gccataccac cgtattcatc cagcaagatt gccatttgtc
    26341 tttgggtatt tcgcagttct tttagcaagt catccacaaa aatagtttca ggtacaaaaa
    26401 gtggatcttg taaaattctc ttccaaacaa tattgtcaaa accgtccaca aagcctgcct
    26461 taaggagact cttggtgtga atgattccaa ttacattgtc cttatcccca tcataaaccg
    26521 ggatacgaga ataattttgt tttaaaatac tttggataat ggcttgacta tcatcctgaa
    26581 tatccaccat aaaggcatcc gttcgaggaa ccataacctc tcgtgccatc agttcatcga
    26641 gcgaaaagac accttgtagc atctcaatct catcagcatc caatgtttct tcactatttg
    26701 tcagcatata ggcaatttca tcacgggtca tcttttcatc cgcatcatcg aatgacatag
    26761 gagtcaaatg gctcaagaaa ttggtcgaag cagctaaaag ccaaacaaaa ggactgacta
    26821 gttttccgat cccaatgata accggcgctg tacgaattgc caaggcatcc tttagattaa
    26881 gagcgattct cttaggatat aattccccaa aaacgatgga aatataggtc aaaaatgcca
    26941 aggatagaaa agttgccacg gcttgtgctg tttcgccatt cccaagccaa gaggcaatca
    27001 cacgtcctag agtatcagtt aaactcgccc ctgataagat tgtaatcagg gtgattccta
    27061 cctgaatggt tgataaaaag tggttaggat tttctagtac cttcagcagg cgaatgtagc
    27121 gtctgtctcc ttcttccgcc ttttgttcaa ctcgggcacg attaagagaa accatggcca
    27181 tttctgtggc tgagaaaaag gcatttaata ccgtcaagat aaacaataaa acaaattgta
    27241 gcaacaaatt ctgactactt gggtcttcca tagttcttct cctaaaatag tatcttatcc
    27301 tttattatat cacaaaattt aatccaatac atattatttt tttcttagcg taacttccat
    27361 ctctctccca aaactggaag ttagtctaag acggatttcc actgatttca cgcgtttttc
    27421 tcatactaaa agctaggttg tgggaaactg gaagttagtt ttagaagtta ctattttttc
    27481 ttagtacctg ttctagccct gcttaaacta gtaaaaagaa ctcctacatc cataagtgac
    27541 ataggagttt aggcttatct tttactgagt tacagttact tctccagttc ggtaatccag
    27601 ttgaagtccc ttttgaacat tgggaactag aacattgaat tccaattctc catccgaaga
    27661 cttggcttca atctgtgaag ctgagggaac taaatcctcg tttgaagcgt agtaaagggt
    27721 tacacggtaa cggacacgct tgttttggtc caaggcttta cgcaccttgc tttcatagta
    27781 gttttgacca gtcgaatact cggcttgtgc ctgatttgcc caggctgtct gaacagcaat
    27841 gtttttagga ttgcttgttg aggcatcaaa accatccaaa ccaccgatta aggcatagcc
    27901 taacaaatga cctctatcga ctgcatgggt ataagagccc tttagattct tgacctgatg
    27961 ccaacctgga ggagtccaag aagttgaacc attcccagtt tctttacgat tcttgtactg
    28021 acgagtggcc ttagacaaga gggcattagc tacggttgga acagtttcct tgcccactgt
    28081 ctttgtttta ttgtcagcgt agggcttact tgaaaccttg gcatctagat ttgttttatt
    28141 accattgacg ataaaagcac ctgagccatt ccactccaga ctccccttta tttgactctt
    28201 gactgcgtct gttaagacac tctctgccaa tgcttgacta ggagcttcag gcgcttgttt
    28261 tttctgacta agcttggttt taggactatt aggtgccgac tgcatctgct tgatataata
    28321 gctccctgta gacaaaagca ataacactag cagtccgatt agtgtctgtc ttgttttttt
    28381 gttcatattt ctccttatct ttagaaaaag gctggttctc cagcctaatt tcctgtaaat
    28441 ttatgaatca attcctgcca ttttgctgga gacaggatag cccatggatc ttgacccttg
    28501 cccaagattc cataacctac cattaaaccg attcctagag ccagagtacc taaaatcagt
    28561 actatgatga ctaaaagtaa acgcttgact acgtagcttg atttcttatt catcttcatc
    28621 acttgcctca atccgctgaa tcttagcacc tagctgcgcc aacttctcat ggaaaccgta
    28681 gtaacctcta tccaagtgaa ccaatttacc gaccacagtt tctccctgtg ctaccaaacc
    28741 tgtcaaaatc aaggctgcac tggcacgaag gtcagttgaa agaacttctg ctccctgcaa
    28801 aggctgtcca ccaacaatac gagctgtatc acggataatc tcagaatgca agcccatgcg
    28861 gcgcatctct tctaggtgtt ggaaacgatt ttcgaaaact gtctccacca tggttgattc
    28921 gccttttgca actgtcatca aggctgtaaa ttgagcctgc atatctgttg gaaatcctgg
    28981 gtggggcaag gttttcacat gaacagcttt tagattttct agttgagaac gaacacgaat
    29041 tccttcgtct tcttcaatta cttcaacacc catttcaagt aacttggcaa tcaagggacg
    29101 gttgtgctcc cagacagcgt ctcgaatcaa gacatcacca ccagtcatgg cagcagctac
    29161 cataaaggtt cctgcttcga tacggtcttg gactacattg tgagtcgtac catgaagttt
    29221 ctcaacacca gtaatggtta tagtctctgt accagcacct ttgaccttgg ctcccatttc
    29281 attaaggaga atggctaagt caacaatctc aggctcacgc gcagcattct caatcactgt
    29341 caccccatca gccagagtcg ctgccatcat caagttctgc gttgcaccaa cacttggaaa
    29401 gtccatatag atatgagcgc catgcaagcg ttctgccttg gcttcgatgt aaccagctgt
    29461 ctgactaatc ttaaccccca tagcttccag acctttcaaa tgaagatcaa taggacggct
    29521 accaatcgta caaccacctg gcatggatac cttggcatga cccacacggg caaggattgg
    29581 ccctaataca acgatggagg cgcgcatctt gctgacatac ttgtaagggg cttcctcagt
    29641 gatgtcgcca gtagcatcca ccttgacaag atgagcttcc tcatcaaagt caaccttggc
    29701 attcaaacca ccaactacct gattcataat aaagacatcc gacaaaatcg gaacattctg
    29761 caagacggtc tttccttcac ttgctagaat agtcgctgcc aacaagggta agactgcatt
    29821 ttttgctccc tcgatcgtca cgcttcctac cagacgatta tcgccacctt gaaccacaat
    29881 tttatccata ctcgtttcct ttactcttga tttcataata atcctctaag cgcttcttgc
    29941 cacaaatgat acaggctaat aaagaaagaa ctcaggatgt agcctatgac aatgctaaaa
    30001 aaggctacta ataaacgaac ttttcttgta ttatcatctg tcacttttaa aaccttctcc
    30061 catctaacaa gatcctttaa aaggtaaaaa ctcacataaa taaagaacat atgactactt
    30121 agagtgaata ataattgaac catttgacta ttataccatc ttctctgttt gtgcgctagt
    30181 ttggaaactt cactcaaaaa ttagggattg tttttcaagt aatcaatcgc atcttgtagg
    30241 gttttaacgg gcacgatttt catatccgtc ttgattgttt tagccgcttc tagggctgtt
    30301 tggtagttgt ttttcgcgtc cggatgcgcc ttttgttctt cttcgctaac agggttatca
    30361 ggagcaaaga aaatagcagc acctgcccta gccgaagcta caaccttctt atcaatacct
    30421 ccaatgtctc ccacattacc atcgcggtca atggtacctg taccggcaac aatacgacca
    30481 ttacgaagat ctgggtgagc tatttgagta tagatagcta gactaaacat gagaccagca
    30541 cttggaccgc caataccagc tgttgaaaag ctaattggga cattgctgat tacctctgta
    30601 cggtcaatca agccgattcc aattccattt ttgccatttt ccaaggtgat gatttttcct
    30661 tctgcagact tggtttgccc atcctcttca taggtgacct tgacggaatc ccctaatttt
    30721 tgagaactga cgtaatcaat caagtctttg gaactatcaa aggtctgatc attgactgct
    30781 gtgactgtat cagagatatt gagaatccct ttaaaggttg aattatccgt cacattcaaa
    30841 acataaactc caaagtactt gagttcgata tccttaccag ctgtttttag tccttgatac
    30901 ttggccatat tttgcgatgt ttgcatgtag aattgattga ttcgcataaa ttcaacatcg
    30961 gaagaaccac ctgtagtctc ctgagcacta cgaatatctg taaaaggtgt caaccaagca
    31021 taaatcatat gagctaaagt ggcatgttga acaccaaccg taacgaattg ataggcacca
    31081 gcttccttat cttctgtgtc atttacttta aggacttggc gaatatcttc cgaaccacct
    31141 ggaacctcta tataataagg caagggcact acaaatgcca agaaagtcac aatcaaggcc
    31201 gcaatgacgt ataagggcca tctaatcttt tttttcattt cttatttcct ccaaaatact
    31261 ctcgggaaca tagcaggcaa tatcctgacc aaacttcaaa agctctctaa cgcctgatga
    31321 actgatatag agatgttcag gtcgactatg taaataaata gtctctatat cagaagacag
    31381 ctgatgattg tagtaatcaa aactggcttc atattgcaaa tccgacgcat ttctcaagcc
    31441 tcgcactagg caagtagccc ccagtctttt tgcgacatcg accaccaatt tatcatgaga
    31501 agacacgact ttaacatttc ccaaatgttt cacagccttt tctaaccccc gtttacgatt
    31561 ttcaagaggg agaaatcctt gtttgtgggg attaaaaaaa atacccacat aaagcttatc
    31621 aaagagtctg ctcgcccgtt caatcatatc cagatgccca tttgtcatcg gatcaaatga
    31681 gcctgtgaat aagccaatct tatctgacat agactgttac cttactaatt ccataaatct
    31741 tttccttcca gatacccaga caggcaattt cttctggaag ttcaacggcc ttatccgtct
    31801 cgcacacaac cataacatct tcagaaaaaa gctctctctc agccattttt tcaatatctg
    31861 ctacgatttg ttccttggca tagggagggt ctaagaaaat gaggtcaaat tccccagata
    31921 cctgttccaa tgccctttct gcatccatct tgaggagttg aaattttcca acttccttgg
    31981 tcatctggat attttcagcc acgatggtct gagccttacg gtctcgctcc accaaaacag
    32041 cactggacat gccacgcgat actgcttcga tagataaacc accactacct gcataaaggt
    32101 ccaagactcg tcccccttca aagtagggac caatcatgtt aaaaatggct cccctaacct
    32161 tatccgaagt aggtcttgtt gtcttgcctt ctagtgtctt aaggggacgt cccccataga
    32221 ttcctgatat gattttcata ctgtttatta taccaaatta tagacaaaaa gagaaagaaa
    32281 accgaacctt gcggttcgat tctctacaaa atattttcgt aagtatcgcg gacttcttga
    32341 ggccaaacac ttgtttgcac ttctccgatg tgtctcttgc gaagtaggaa catggccata
    32401 cgagattgtc caattcctcc accgattgtc aatgggaata ggccattcaa caaagacttg
    32461 tgccattcca attccaagcg gtcttcatca cctgtaattt ccacctgacg tctaagagtt
    32521 tcttcatcta cacgaattcc catagaagac aactcaaagg ctccacctaa agactcattc
    32581 cagacaagaa tatcaccatt tagacccttg tagccattct cagactcgct tgtccagtca
    32641 tcatagtctg gtgcacgtcc atcgtgcggt ttaccatctg gcaactcgcc accgatacca
    32701 atcaaaaaga cggctccaaa ttctttacaa atcgcatttt cacgttcttt cggtgtcaag
    32761 tctgggtagc gttctaccaa ttcttctgta tggataaagg tgatttgttt tggcaagata
    32821 gactcgatgt catagcgggc ttcaacagct agctcagtca ggcgaatagc cttataaatc
    32881 ttctcaactg tttcttttag ataaacgatg ttacgcttac catttggaat aaccttctcc
    32941 cagtcccact ggtcaacata aacagagtgg gttgcatcca aggaatcctc atctggacga
    33001 agggctttca tgtggacaaa gagaccctct ccttcaccaa agccaaaacg agccaaggtg
    33061 tggcgtttcc atttagcaag tgagtgcacc acttcataag tagcatcagg gatttggaga
    33121 accttgaccg atactggatt ttccacacca gacaggttgt cctgcattcc gtcaccgacc
    33181 ttactcaaga taggaccttg aacttcgaca acttctagct tatctttcaa atactgggta
    33241 aaagtgtttt tgacaaagga aatttcttct tgttgatgga taaaactttt cttcatagac
    33301 aactcctcaa aaatttaata aacgtattat acacctattt ccaagaaaag aaaagagaaa
    33361 atttaaaaaa aatcagtgtc actcaaaaca ctgatttcat agacctttta gtcattgcga
    33421 ccaaagatac gtagaatact taggaaaaga ttgataaaat caagatagat gctgagagcc
    33481 attgacacca cccagcctgt cgctacacga ccttgtgatt gttcataggc gaggcgaatc
    33541 ttttggttat cccaagcaat caaccctgaa aaaaccaaaa ccatggctac gctaatcata
    33601 taatcaaaga agccactagc caagaaaata ttgactacca tagcaatcag taaaccaatg
    33661 agagctgcca tcattgctcg accaatccca ctcaagtctt tcttggtaaa aataccaact
    33721 gccgccatga caaagaagag aagggcgctc gatacaaagg cagataaaac tgtacccgga
    33781 gtatagaaag ccaccacaaa actaagggta aagccgttta aaacggagta aagtaaaaat
    33841 actggaagag cagctggact atttcttgaa gccatgctac tggcaacgaa aaccaaagcc
    33901 aactccgcaa aagtagcaat ggtcaaccag agacgcccct gcatcaacaa gtaaaccaac
    33961 tgagactgaa agaccgtcaa cataaggcct gataccaaag cagatagtcc gattcccaga
    34021 ccaacaaagg cataaacctt agcgtaaaat tgattgagac ctgcacggtc atgtataata
    34081 gtgtgattca tccttttctc cttttctgtg aacatctttc cttgattata acaaaaaaag
    34141 ttaaaattag cttaaatgga agattaaaat accggctgca actgcaacat tcaaactctc
    34201 ggcctgcccc ttcatgctaa tatggaccaa ctggtctgca ctttcagcca taaggggact
    34261 aattccttga ccctcatttc ccataactag tacaaaattt tctatagaag gcagttctct
    34321 gtaatcaaca gaatctttag atagggttgt tgctagcact gggatagcta cctttttagt
    34381 ttcgtcaaga agcgcttgac tagtcatccg gtaaatgggc agatggaaat gactaccttg
    34441 catggaacgt agggttttga gactgtagat gtctgccgac ttatctgaaa caatcactcc
    34501 tgtaaaacct gctgcatccg cagttcgaat gatagttcct acattaccag gatcttgcac
    34561 atcttccaaa aacaagaact tgccctgact caaatcagct tgtcctactt cttctttttg
    34621 aaccacggca acaattccct gtggagtctg agaatccgcc aaatctagca aaatatcctc
    34681 tgaaatccag acagtttgcg gaaaagcagc taactgattt cgataatttt ctagggcaaa
    34741 gattttctca atcgtcactc cagcttggac agcttcttca aacaagtgcc agccttcaat
    34801 caaataggca gacttgcggt attttttttg gtgtaatttc ttagcatttt ttaccacaga
    34861 attggctttt gaggttataa tagtcataga aatattataa cacaatcaaa ggggtttggt
    34921 atgcaaaagg ttagaatgat tgcccaaggt agggtgcagg gagtcggctt tcgttggggt
    34981 gtttatagcc tggcccttga aatcggtggc atcacaggtc gggtatggaa taacgacgat
    35041 ggcacagtgg aaatcttagc ccaagcagac tcatctgcta tcatggcaaa atttatccaa
    35101 gaaatccgaa aaggaccgac acctttttca aaagtaagct acttagatgt caaactaagc
    35161 aactttcctc cctactctga ctttaaaatc gcaaattagg tctccagaac tattgtatat
    35221 tttgtaaaaa aacagtagaa tagaaaggta taatttttaa agaaggaata aaaacagtga
    35281 aatctattaa acgttttgca ttctcggcta tgggagtggc tatgttgctt gtcttgactg
    35341 gctgtgtcaa tgtcgataaa accacaggtc agccaacagg atttatttgg aatacgatcg
    35401 gagcgcctat ggctgaagcc atcaagtact tcgctactga taaaggtcta ggctttggtg
    35461 tcgctatcat tatcgtaacc attatcgtac gcttgattat cttaccactt ggtatctacc
    35521 aatcatggaa ggcaacgctt cactctgaaa agatgaacgc cctcaagcac gtccttgagc
    35581 cacaccaaac gcgtctcaaa gaagcgacta ctcaagaaga aaaactcgaa gcccaacaag
    35641 ctctctttgc tgctcaaaaa gagcacggta tcagcatgtt tggcggtgta ggatgtttcc
    35701 ctatcctcct tcaaatgcct ttcttctctg ctatctactt tgctgcccaa catactgaag
    35761 gggttgctca agcaagctac ctaggcattc ctctaggttc tccaagtatg attttggttg
    35821 cctgtgctgg tgtcctttac tatcttcaat cgctcctttc acttcacgga gtagaagatg
    35881 aaatgcaaag agaacaaatc aagaaaatga tttacatgag cccactcatg atcgtcgtct
    35941 tctccctctt ctcaccagct agtgtcacac tttactgggt tgtcggtggt ttcatgatga
    36001 ttctccaaca gtttatcgtc aactatatcg ttcgtccaaa acttcgcaaa aaagtccgtg
    36061 aagaactagc caagaaccca ccaaaagcaa gtgctttctc taaaccaagt ggacgaaaag
    36121 acgttacccc tgaacaacca actgctatca caagcaagaa aaaacacaaa aatcgcaacg
    36181 ctggaaaaca acgttcgaga taagaagaaa aaggcttagc tgatttgcta agtctttttg
    36241 caagtcaaaa gcccgatgtt tccatcaggc ttcttttcta tccatgtaca cgtttcatat
    36301 aatcttgata actttcggta tccatgagtt gtttagcgtt cttgacgcga tctgctgttg
    36361 gtggtttgac tccttcgagg gaatatggaa ttccaagttc acgccacttg aactcaccca
    36421 tggtgtgata aggtagaatt tcaaacttat caacattttt gagggtcttg acgaacttac
    36481 caagttcaat caagtcatca tctctgtctg tcaatcctgg aactagcacg tggcgaatcc
    36541 agacaggttt tccaatatct gatagatact gggcacaagc caagatattt ttattggttt
    36601 ggctagtgac aatcttgtgc tgttcttcgt tgatttcctt gatatccaaa agaaccaagt
    36661 cagtgacagc catgagtttg tcaaacttct caaggtaacg tggtttatta cggaaaggaa
    36721 gagcacaggt gtccaaggta cagtggattc cttgttcctt agccttggtg aagagagcaa
    36781 tcaggaaatc aatctgcaag agagcttctc ctccactgac tgtaatccca cccttatttc
    36841 cccagaaacc acggtagcgc aaggcctctg tcaagacatc atctaccgtc cgttcacgtg
    36901 acttattgga ctccatagcc caagtgtctg ggttgtggca atactggcaa cgcatgtgac
    36961 agccctgcaa aaagacaata aagcgaatac caggcccatc tactgaccca aagctttctg
    37021 tcgaatgcac cattcctgtc acttgtccat aatcaattgt ttcttcagac atatcgttac
    37081 cttccttgaa aacgttttat agttttatta tatcacgact tgaaggaaaa acaagatttt
    37141 tgcctatttt ttagaaagca atctgttttt caatttcatt ttcaatctat tatcagatta
    37201 ttcttcaaaa tcgaagccat ataaggttgc aaaatagtcc tcagggcgct ctgcacggcg
    37261 gatttgacgg gctttacctt cttcggtata gaggatttcc gcagaacgta atttggcatt
    37321 atactggtag cccattgaaa atccgtgggc acctgtatca tgaatgacca gcaaatcacc
    37381 gatttctgta tgaggcagtt cgcgattaac tgcaaattta tcattgtttt cacagagtga
    37441 accgaccaca tctaccactt cagctggtcc atctggatgg gtcacgttgc taatatgatg
    37501 gtaagctccg tacatagctg gacgcatgag gttgactgct gaggcatcca cacctagata
    37561 ggtacggtag gtttccttct tatgagtgac tcttgtgact agagcaccgt gaggtgccag
    37621 cataaaacga cccaattcgg tgaaaatctt gacctgacca agacctgctg acgtaagaac
    37681 ctcttcatac accttacgaa ctccctcacc aatcaaggcg atatcgttcg gctcctggtc
    37741 tggatgataa ttaacaccaa taccgccaga aagattgata aagtctagcg aaatgcccaa
    37801 cttttccttg atttcaacag ccagttcaaa gagctgacga gccaactctg gataatagag
    37861 atgggtcacg gtattggacg ctaggaagga gtgaatccca aaagtcttgg ctcctttttc
    37921 cttcaagata gcaaaggctt caaagagctg gtccttggtc atgccaaact tagcctcccc
    37981 aggattgtcc ataatgtctg tccccagttc aaaaacgcct ccaggattat aacgacaaga
    38041 gatgatttct ggaatgcctg ctactctctc cagatgttca atatcttcaa aggcatccaa
    38101 gttaatggtc gcacccaatt cacgtgcata ggcgtattcc ttgtctggcg tgttgttgga
    38161 agagaacata atctcagaac ccagaaagtc cagtttatgg ctcatcaaaa gctctacata
    38221 actagagcag tccacaccac aaccttcttc ttggagaatt ttcaaaatag ctggagttgg
    38281 agtagcctta actgcaaaat attccttaaa gcccttgttc cacgaaaaag cttggttgac
    38341 ggctcttgcc ttctcacgaa tccccttctc atcatataag tgaaagggag tcgggaactc
    38401 ggcaacaatc gcttctaact cttctctatt gataaatggt gttttcataa gcttccttct
    38461 attctgtttg caaagaaagg ctgggacaat cgttccaacc tttagttcta tctcttattt
    38521 atcttcgtca aagatattgc caacctcaac atcgatggct tggttcttga catcaatatt
    38581 ggttaccttc aagagtgact tgtagtcaaa ctgcttttca cgttcttctt gggcattgtc
    38641 cgcaaagacc gctacacctg ccagttctga gtcgaactcg cgcaagagac taatcatacc
    38701 attgaccgtt ccgccacctt tcaagaagtc atccacaatc aagacacggc tgcctgcctt
    38761 aagactacgt tttgaaagga acattttctc gatacggtca ccacttgaac ctgaaacata
    38821 gttgacgcta acagttgaac cttcggtaat tttcaggtca cggcgcacaa tgacaaaaga
    38881 gacattgagg acattggcaa ctgcatttgc aagtggcaca cccttagttg ctacggtcat
    38941 aaccgcgtca attttttggt ccataaagct tttggcaata atacgaccaa tatttttcaa
    39001 gatggctggt gtgctaagca aatcagacag atagatataa ccacctggca agatacggtc
    39061 actttctgac aacttggtac gcaagtcttc aaccatttcc ttagcatcct gactcgaaat
    39121 agacggtgtg aagatgacac ctccgccagc cccagtcact gtctggatat gaccgatttc
    39181 aatttcctca aaggcgcgtt tgataatgac gatatcttct gagatggatg atttagcaga
    39241 ctcatacttt tcagcaaaag tattgagact agttagttta taaggattat taatcaaata
    39301 gttggaaatg acaaccatcc gatcacttct tcttaatttc atttctattt cctattccat
    39361 ttttattcaa aaaatcaaaa agcaaactag aaagctggtc gctggtggtt caaaacactg
    39421 ttttgagatt gtcaatagaa ctgacaaacc ctgtaatata cctgcatata tacatacgac
    39481 aaggcgatac tatcctagtt tgaagagatt ttcgaagagt attcattttt gtcttttact
    39541 tattatacca tattcacata aaaaaacgaa cattcttatc ctaaaaaatg ctcatttttc
    39601 ttaaattatc aatctaaatc tggtttatag aaggaacgat tatccatagc gaagatttta
    39661 ttggtcatct ctcctttatc caccaaagcc agagctgttg acatcatcat catgcttgca
    39721 tccagattgt caatcatatg gataatctct gcctccataa tacgtggacg gactggactt
    39781 ccatattcaa gcaagccgtg gtgactgagg atgacatgac gaagcaaaac gacttcttcc
    39841 ttggtatcat cgatgccgag ttccataact gtcttggtaa tttcgctatc aatgagagcg
    39901 atatgtccaa gaagattacc tcgcactgtg tactctgtct ggtctggccc cgtcaactcg
    39961 ataaccttag ctaagtcatg cagcataatc cccgcataga gcaggctctt attgagctga
    40021 ggataaactt cgctaatagc gtctgccaaa cgcaccatgg tcgccgtatg ataggccaag
    40081 cccgtttcaa aggcatggtg gttggtcttg gcagctggat aggagtagaa ttccttatca
    40141 tacttggtgt agagatttcg gacaatccgt tgccagacag gattttcaat tttgaaaatc
    40201 atttgcgaca tgtagtcacg aatttccttg acatcaactg gtgacttgac cttgaaatca
    40261 gctgggtcat tgggttcacc agcttgaggc aggcggagag taatttgatt gacttgaggg
    40321 gtattgttat aaacttctcg gcgtcctttc atgtggacaa ccttacctgc ggtaaaggcc
    40381 tcaatgttat gaggttgggc atcccagagc ttcccatcaa tctcgccact atcatcttgg
    40441 aaggtaaagg ctaggtagtt tttcccagct cgagtttgcc tcaggtcagc tgatttgatt
    40501 aggtaaaagc cttcaaataa ctcatctttt ttcatgtgac taatcttcat attcttcctc
    40561 attttcttga aaatggagta gatcaagcgc aggctcacct tctgacaact caatgtgacg
    40621 gagcgtccgc tcgatagcta tggtacgacg gtttaataat tcatcaatat tgccagaggc
    40681 atgttggaga tgtttttgtg ccttgaccag aataccacca aacttgccaa actcggtctt
    40741 gacactggca agagtcttgc tgatatggtc ggcactcttt tggatattaa gggtcttgaa
    40801 accaactgat agggagttaa gaagggctga tagggtactt ggtcctgcaa cgataatctg
    40861 ttcttcccgt ctcaaatcat caaagaagac cggattgcgc acaatctctg aataaagacc
    40921 ttctgtcgga acaaacaaga ttccaaaatt ggttgtccga ggcggtgcta tgtacttgct
    40981 cttgatatcc ttggcaaagc gcttgacgct tgctaggagt gacttacgac agcgttcaat
    41041 ctcatccttg tcacctgtct cataggcttc ttccaagcgg taataatctg ccagtggaaa
    41101 cttagagtca attggcagat agacgtattc ttggtcgcct tgtccgggta acttgatggc
    41161 atactccact cgttcactag agttttcaac cgttgcgtat tctcgttcgt actgggcagg
    41221 tgtcatgatg tcttcaataa tttgccccag ttgcaattct cccagaatac ctcgcgtctt
    41281 ggttccagag agaaccttgt taagagctcc gacatcacgg gcaactgtct gcatttctcc
    41341 aaggccacga ttgacagact ccagttgttt agaaactgtt tcaaaggaag cctgtaagcg
    41401 tgtctgcaag gtcttttcta gtttttcctc gaccgtctgg cgcatttgtt ccaaacgttg
    41461 ctcatttgat tcctgcaagg cttggagacg ttggtctgtc ttgtctctag tttggaggag
    41521 attatctgtc atttcttgac ggacttgggt caggccttgg tgcaattcaa tccgcacttc
    41581 ttgcaaacgg tcgctgacag ccacttccaa atctttttgg tctaactggc tggcttgtct
    41641 ggcttggtca aagcggtaat ccaactggtc tgacaaatga tctgcctgat cctccaagct
    41701 cttacttaag tgtttctcct gcctatcctg cctttgccaa atcagaaaga gaccagctag
    41761 gttggcaatt aataatagaa taagtaaact ttccatccta cctcctgtcc ttgctatgca
    41821 gtacgaccac ataaccatct gggcaagtta ccgacacttc cctatctata tattcgttag
    41881 aagcgtacac ttttttaaag aaaaaattct cctctgtcaa ctcatactta gctccaagaa
    41941 tagtcagctg gctatcccga actggcataa aggctagata gtcgtagtct gaacgaggtt
    42001 ctagctgact ggtcccttct gaacaatagg caatcaaatt ttgcccatcc tcaatttcta
    42061 tttgacgcat atagggtgcc aacttaggat tgctaggtag aaagacattg gccaacatat
    42121 ggtcaatacg gccacccaag gcaccgaaaa tagtgacctg agcctgagga ttttgttcaa
    42181 agatggttaa gagagccaat tccagatctg tatcatcctt ttctggtcgg gcttggacaa
    42241 aatactgggc acgtttttga atcacctgtc gctcttcttc cgtcacagaa tcaaaatctc
    42301 cgactgctag agcaagaggt aagtcttctt ccaagaccca gagcgagcct cgatccaccc
    42361 caacaaaagc atcaaaatct gtccgataat gaccgcggtt tccgcctgca aaaactgcaa
    42421 ccctagtcca gttgttttct gagagtttgt actcgctcat tgacttctcc cttaaagaca
    42481 taggaacctg ctacaaaaac agtcgcacca gcttctttgg cttgagcaat agtttggtca
    42541 tcaatcccac catccacttc gatttcaaag ttcaaacctt tttcctcacg aagagcaacc
    42601 aactcacgaa ccttatccat ggtttctggc agaaaggctt gcccaccaaa acctggatta
    42661 accgtcatga ctaaaacttg gtcaactaga tgaaggacgt gcttgatggc ttcaactggt
    42721 gtgccaggat tgataacgac tgaaggctta actccgagtg aacgaatttt ttggagggcg
    42781 ccatgaatat gaggtgttgc ttctacatgg atactgatga tgtctgcacc tgcacgcgca
    42841 aaatcttcca gatgatgctc agggtttgac accatcaagt ggcaatcgaa aaccatctta
    42901 ctatgaggac gaaggctctc gaccacacct gcaccaaaac tgatttgcgg tacaaaatga
    42961 ctgtccatga tatcgatatg ggcatattct gccccagttg cttctagacg tttgatttca
    43021 cgttcaaagt tggcataatc tgctgccaga attgacggag caatcttgta ttgagacata
    43081 ggtttctcct tattttggaa tttttttgct gactttttta taggtttctc tacgattttc
    43141 aatttcacta aggaattgca ggtaattgtc aaaacggaag gttgcaataa caccctcttc
    43201 aacagctggt ttgacggcac aagacggctc atgggtatgg gtacaagtac ggaacttaca
    43261 atctcggcta acagtagcaa tctctgggaa agcctgattg aggtcttcag cccttgatac
    43321 ttcatagtcc aaggatgaaa atcctggtgt atctgcgatt ttacccccgt tgagattgta
    43381 aaaactaaca gctcgagtgg tatggcgacc gcgacctaga ctgtctgaaa tttctcccgt
    43441 ttcaagattg aggtctggtg cgattttatt gagaagagtt gacttcccaa cacctgtctg
    43501 ccccataaag accgtaacct tgcctgttaa caaagacagg agttcctctt tactggtcac
    43561 aaagtcatag ccgatgtcac cataggtctg ctggtaaaaa tccagttctc ccctatcttc
    43621 caacaaatcc attttggaaa tatagacaat gggatggatg cccttgtgct ccaaaagaac
    43681 caagaaacga tccagcaaat tgctgttaaa atcaggttcc ttgacggaca tgattactac
    43741 agcttgatcg atattgacaa taggcggacg aaccagactg tttttccgtt cgtgaatttt
    43801 gaggatatag ccttctgaat tttcctcggc agagaaatct acccagtccc caacataagg
    43861 ggtatggcct tttttacgga aattcccacg cgcgcgtgtt tgataaacct ggccatcact
    43921 ctccacatag tagaaacctg ccaaggcttt aatgatttgt ccctgcatct tagagtcctt
    43981 gccctttaag tgcgtctgct agaccggcaa attctgccaa gctgagagct tccccacgca
    44041 cacttggtga caagcctgcc tggtccaaag ccttggtcag cttgtccttg acctcttcag
    44101 tcttaccaaa gtaacctgtc aagttattcc acaaggtctt gcggcgatgg gtaaaactag
    44161 ccttggaaac cttaaagaaa aagttctcat cttctactgc tacggctggc tctggacgac
    44221 gcaccatttt caagatggct gaatccacat ttggcgctgg cacaaagacc gtacgaggca
    44281 cgataaaggc aaccttggct gtcatgtaat actgcacggc gatagacaag ctaccgtaag
    44341 ccttggtgtt aggctgggct gaaatgcggt ccgctacttc tttctgcatc atgaccacaa
    44401 actcacaaaa aggaatgcca ctctcaatca agtgcatgag aataggcgtc gtgatgtagt
    44461 aaggcaaatt agccactacc ttgattggca ggttaggatt tttaaaattt tggatatgtt
    44521 gcgccaaatc aaccttgaga atatcttcgt taactacagt cacattatca aaatcacgca
    44581 gggtatctac caaaattggc accaaacggt ggtcaatctc aaaagccatg acttgggctg
    44641 cacgctcagc cagaaactcc gtcaaggcac caatacctgg cccgatttcg atgacattga
    44701 cctggtcatc aatttcagcc gtatccacaa ttttttgaag gatattggta tccgtcagga
    44761 aattttgccc gaaggacttt ttaaaggtaa aaccgtgacg ctccagcact gccttggtca
    44821 ctctataatc tgcaattctc atctattctc ttttctatta tctgttacta ctattgtaac
    44881 acattcccct tgtattttgg gaatgaaaat cataccaaaa aactatcttt cctcatgaag
    44941 aaagatagtc ttggaaatct ttaaaagtgg ccttaacagt tctctcgaaa catgcgttca
    45001 aaaaaatcag cttcttgata acttcgattt tcaggtaggg tcaaatccac atcctcctcc
    45061 acatcatcca ctgtcagttc aaccgtctga ggtaaatttt tcaaacgata atgcttttgc
    45121 ctttgccctt caatactagc aaaatcaagc aaatagccat gcactcggat ttgaaccaaa
    45181 aggagatgat tggtcatatt ttccatgatg aggatatctt ctaaaccacc tctggcacta
    45241 ggataatcag ataccctgcg aatacggatt ttttcacaca tgagcaagtt tcctcatatc
    45301 aatgatttca tcagccttat tccagactag gggattatgg gtcgcaatga tgataattcg
    45361 attttcatct ttcaaatcca ccaagagatt cataacctcc tctgaatttt caggatcaag
    45421 agctgctgtt ggttcatctg ccaaaatcaa gggtggattt ttcaaaatag tcttagcaag
    45481 ggcaactcgt tgggcctctc ccccagataa agtataaatt ttttgttcta aatccaaata
    45541 ccctagatta actttttcta aagcccccac ttgcctttcc aaacgttcta cttttgagat
    45601 tttctgacca acaaaaccca aatccaaatt ttctttgatt gattggtttt ctaagaggcc
    45661 aaaattttga aagagatagc ccatctgatc tcgaaaatac tcacgagtgg gaatggtttt
    45721 taaatctttc ccctgataga gaacccttcc tccatctatc ttttctagct ttcccaagat
    45781 attcagcagc gtcgtctttc cgcttccact ctttccgatt aaggcataaa ccttgccctt
    45841 ctccagcttg agattcaaac cagagaaaat cgcgcggtca ttaaatttct tttccaatcc
    45901 ttgaatatca atcatcttat tttcctttca atactgccat gctaccagct tcttcttttt
    45961 tgtcctgcct tactaaaatc aagagggcgt taagcgtaaa caaagctaca actagagcgc
    46021 taatcaaacc atctcttgtc aaaatactag ataggactag gccaagcaag agaactcctc
    46081 cttgcgccag taaatacttg ccatgaagct catagattgt cataccagca agacgtttaa
    46141 tcataagctc ccgtctgaac tgctcaaaat agagaagatt catggaatca aataacaaga
    46201 tagccgtaga cagggtcaaa atcgtcccaa taaggagaga gtaaaactcc acccgtttgt
    46261 catttagtac cttggcaaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
    46321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
    46381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
    46441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
    46501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagccttac ctgtgggaag tagtgtttct
    46561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
    46621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
    46681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
    46741 agcgcggcga gacatagata acattccctg acggtatgta gtcactgaga cgattgccat
    46801 ctaggtccac ttctgctcca tctgagaaat tgtcaacatt gctcataata taaaaagagt
    46861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
    46921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
    46981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
    47041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
    47101 tcatccgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
    47161 caagtagatg gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
    47221 gaagagcaat gatgaccagt tgtaccgttg ccataaacaa ggcaccttga taccagagaa
    47281 tccccaatcc caaaagactg gataccagca ctgagcagat aagctgtctc acatcttcta
    47341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
    47401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
    47461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
    47521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
    47581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
    47641 ccttggagga aatggtcaga ccttctggaa gctttccctc accataagtg gcataggtaa
    47701 agcgtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
    47761 ctaccgccaa gtgactcaaa gcctctgtca cctcttcgcg actagctact ggttgattta
    47821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
    47881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
    47941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccaagtaaag
    48001 ctaaacaata gggctatacc attctaaaca ttatagtaga atgcaacttt ctctccccaa
    48061 gaagtacgaa tccatgcacg agaagtccct ccagcaccag catatccctt gtcagatgaa
    48121 ccagtttttc tgctaacaac tgttgaacta tggtattttg aagggtgata gtagtttgag
    48181 taagcaccac cgttacctga accataagtc caaacaccac cttctgggta ttgaacggct
    48241 gcagaggcaa ctgctacact tccacctaat gttgctgcaa tgctcgctac aagagctaat
    48301 tttttaactg tttgtttcat attgatactc ctctattttt gattacaaga ttgttgagtt
    48361 acttgctcct ctttccatta tcaacgttga tactattata ttaccaaatg atattctaaa
    48421 attatttgtt tttctctaaa ttgtcaaaat agcaccctga aatgaacttt tatagtcatt
    48481 atactccatc tttatcacac tatcaaggac atcaatgtcc ttaaaatcta actatttcat
    48541 attattttta gcttatatct aaaaaaacag ttctaaagac gaactttaga actgttttga
    48601 tacgaggata aggacatttt tgtcactgat tcactatgtt tataaatatt tttttaaatc
    48661 ttcttgccat tgtttttcta acatagtaac taaataagaa ttttctatta tatcagcaaa
    48721 tagcttcgat ttctgataga actgttcggc agaaacataa tcattgttta ttattagaga
    48781 taatttccac tccaacatta atataattgg tttcttctgg aaatcttgtg ttttttccat
    48841 tatatgatta aggctaaaga tataagctcc tagtgaatca taagacgaca agttatccaa
    48901 acaggctaga cccgaaaaca aagtgttact taaagcaaac agatattctg atgcaattaa
    48961 ttctacatga tttgtcaaac gaactaaaaa cgaatgaatt ctgttaattt cttcaatctg
    49021 attttgacct tgttttatct ttgtaagcac tatagcaaaa tataagttga taacttctaa
    49081 ttcatttatc aaaaacaatt ccttatcata aattgtttta aaataatcgt ccagtacggt
    49141 ttccccgtat tctggtcgtc cacttcgaat aacatctatc gttgctctag tagcttcaaa
    49201 ccatactttt tcctcattag gaagttgctc ataaaataaa tcctctatct cttccaaaca
    49261 cgcttccttc ttatcgtact cctcttcttt accatagatt ggttcacgta aaatctggta
    49321 tttcaattct aaataagcag aaggaagagc tgaaaaatcc ggcataaggc tataaactgg
    49381 aactcctagc cggcgagcaa tataggctaa cttgggcaaa ctcggttgcg aagctccact
    49441 ttcaattcgc gacagttgac gaactgtcag ttcttgctca tctccacaaa aatctggacg
    49501 actaattcct ttttctatcc gaatctcttt aattttttga ccaattaaca tcagacgcct
    49561 cctattctac ctgcttcgaa aaatactgtg aaacttaaaa aattgtaacg gctacatctt
    49621 tcctactcat aagatttcat agcttcttcc acttctgcca aagtaacccc aaacaactct
    49681 aggcgtttga ggagttgctt gccgttggaa tagccgattc ggagagtctc tccgaggtat
    49741 tctctacgct tacggctgtc tgcccctgct agaaaaccaa ggcgaatcaa atcgctacga
    49801 ctaatgtcaa actggctctc atgttcaaat tgttctgtca cctgagctag agccgttttc
    49861 aggtcttcat agctggcatg ctcaattccc agagaacgcc ccttggtctt ggacttggga
    49921 acagcttcat ctcgcttgag aaaggcatgc tgaactgttg gaatgaccgt catgatcatg
    49981 cgccgaatcc gttctccatt aaaatctggg tctgtaaaga caatgactcc atgacgttgg
    50041 tgcaggcgct gaatccgctc tatatcctga tcattgatgg cagaacctcg agtctcatag
    50101 gtctccacat cgaaataacg cttgagattg accgtatcat cacgcccttc aaccacgata
    50161 acttgagaaa ttttctcttt cattacttgc tgtccagtcc aaaaattcgt tctgcatttg
    50221 cagtcgttgc taccgccagc tcttctgtcg tcataccacg caagtcagcg ataaagtcga
    50281 ccacataacg agtataggct gttttatttt cacgaccacg cttgggtaca ggtgctaagt
    50341 aaggcgcatc tgtttccacc aaaatcttgt ccaaaagtaa ctctttagct gcttcttgga
    50401 ggtcagttgc cttcttaaaa gtcaccactc ctgagaagga aatggtcata ccaagatcca
    50461 caaacttctc tgcccactca agcgtccctg aaaatgaatg catgatacca ccacgaggac
    50521 caacgccctc actcttgata atctcatagg tatcttccag cgcatcacgg gtatggacaa
    50581 caaaaggcaa atccaagtcc ttagatagct gaatctgacg gcgaaaaacc tgctcctgca
    50641 cctctttggg cgctgtcatc caatggtaat ctaagccaat ttcacctaaa gccacaacct
    50701 tgggatgttt taacttatcc aacaagtaag cctcaacttc ctctgtataa gtaccagctt
    50761 ctgtaggatg ccaaccaata gtcgcataga gctgatcata ctcatctacc aactccaagg
    50821 cacgctcaat cgtcggttta tcaaaaccaa caatattcat ctgtgtcaca cccatctcag
    50881 cagccaaggc aatttcttct gcctcacgac ctgcaaattc ttctacattc aagtgtgtat
    50941 gtgtatcaaa aatcatctct tctaacctcg ttttctatct tctattatac caaaaaagag
    51001 gaggggcacc taatttttcg gtttcccctc ctctcttcaa tagagagcta ttctgctatc
    51061 ttttctatcc gatattgccc atctcctatt ccacagttag agacagaaga gattggctac
    51121 attgatagaa tattcctatt cagctaaagt atgtgattat cttgggttct cacttttctc
    51181 acccatcact aggattgatg acttctcaaa atccccctta taatctaact ttaagtagag
    51241 aatagaattt tctagctgtt ctattttcta cgtctagtct ttcttcctag caaagcaaaa
    51301 ccacttgttg ccaccactag accaagacta gcaagtgctg cacttgatgc tgaacctgtg
    51361 ttaggtaatt gtttgccagc aggtgactgg taggtaacat cttgcattgt tcctgcagtt
    51421 gcttgcggtg cacttgttgt cttaggagca gcattaggag ccactggtct cttaggaact
    51481 gtaaccatgg caatggcttg cactccaatc gtttctgctt ccttcacatc ttccatagtt
    51541 ttcgcatttt caatctcttt gagagctgct tgtttttctg cttccactct tgctaaaagt
    51601 tctgcttttt ctttatcaga aagcggtgcg cctttgattt catcctgctt gtccttggct
    51661 gctttttcaa tggcattttt agctgattct ttttcagtag ctaattgctt agaagcttgt
    51721 gattgagctg agttttgtga acctgtgtga gctgatccac ccgcctggct accaccgcct
    51781 tcattcgcat tagcatctga gcttccagta ttgcctccct tatctccacc tggtgtattt
    51841 tctagcttat actctggtgt agcttcttga gttacagatt cacctttcgc agattgttga
    51901 actgtatctt ttcctagaat cgtcactact gaaccatctg ggaatgtgat tgttgctgta
    51961 ccatctccag ctacttcaac tttatagtaa aataaaataa taacaggaca aatcgatcag
    52021 gacagtcaaa tcgatttcta acaatgtttt agaaacagag gtgtactatt ctagtttcaa
    52081 tctactataa catcgcttcc gaatccattt gcatctactg aactttttta caaaaataaa
    52141 aatcagtaga ctcgagttcc tactgatttt tgatagaatt cgtttggatt atgcagccaa
    52201 aactttgcgt cctttacgac gacgagctgc caatacgcga cgaccatttt tagttgacat
    52261 acggttacgg aatccgtgtt tgcgcgcacg acgaagttta cttggttgat aagtacgttt
    52321 cacgatgaat acctcctcat agattttgta ttcgtttagc cggctataaa gtgatcagtt
    52381 actaaacata ctttactatt ctatctgatt ctttcacttt tgtcaatagc cctaggcaaa
    52441 tgtttccagc tttttcgaat gcaagcccta tctacgatac tgtttcaaga aacgagtcat
    52501 cttttcttgg atttgggcta actcatcaac acgaggaagg taaacgatac ggaagtggtc
    52561 tggttcctgc cagttaaagc ctcgaccatg aaccaagaga accttttcct gcttcaagaa
    52621 atcaaggaca aactgctcat catcatcgat acggtacata ttgcggtcga tttttgggaa
    52681 gatatagagc cccgccttgg gtttaacggc agacaaacct ggaatatctt gaatggcatt
    52741 atagatgaaa tttctttgct cgtagattcg tccaccagga agaagcaatt catcgactga
    52801 ttggtgaccc cccaaggaag tttgtacgac ttgttgggcc aaaacgttag agcaaaggcg
    52861 catattggac agcatattga gcccttcgat atagccctta acatgagtct tagggccaga
    52921 caagaccatc caacccacac ggaaacctgc tatgcggtgg gattttgaca gaccattcat
    52981 gctgacacag aagacatctg gtgccaagct cgccacaggc gtatgcacat gtccgtccat
    53041 taccatgcgg tcatagattt catccgcaaa gataatcaaa tcgttttgac gggcaatctc
    53101 aataatctcc agcaagagtt tcttaggata aagggctcca gttgggttat ttggattgat
    53161 aaggacgatt gccttggtat tggaagtgat ttttgacttg atatcgtcaa tatctgggta
    53221 ccattcaaca gcttcatcac agatatagtg aacggcattt cctccagcta ggctgacagc
    53281 cgccgtccat agaggatagt ctggcattgg cactaagacc tcatccccat tgtccaaaag
    53341 cccctgcatg gacatgacaa tcaactcact gacaccattt ccaaggtaaa tatcatcaat
    53401 atctacgttt gggaatttct tcagctggca atactgcatg atggccttac gggctgagaa
    53461 aattcctttg gagtcagaat agccttcact atcacgcgca ttcataatca agtcatgaat
    53521 gacctcgtct ggcgctgtaa agccaaattc tgctggattt cctgtattca gacgtaaaat
    53581 cttttctcca ttcgctcgca tccgcatggc ttcttccaat acaggaccac ggatatcata
    53641 agcaacatgc tctaacttac tagacttgtt atattctttc atcttgtttc ctcaattcat
    53701 caggatagta acattatacc actagaaaga gaatgcgaca agtttactga aatgtgttac
    53761 tagtttcgta tagaagaaaa accttgctaa aggcgaggtt aagaacgtag agatagcagg
    53821 tattttgcaa agacacatca cataccaaaa gataaaccta gaaaaagcaa gcctagaaag
    53881 gagtcataaa gaagattaaa catgaggaaa agcccccata tcatcaagta atcccaacgc
    53941 ccacttcgtt ttgcaactag aaataagatt agatggtaga gtacatgaaa aactaaaaat
    54001 ccaataaaac ttggataaag aagcggtacc agactctcta attgacagat catgatcact
    54061 tctaccaaga ctgaaactag gataattcca taataaagga aatttgattt ttgaaaagag
    54121 tttttcatca ttctcccttc cttcacttct ttcctgctat cctttctttt attttatcat
    54181 atatttatat agagtttaag ccctaatatt cttttgaaaa atactttttt tgctttactt
    54241 ctatagtgaa aaggtttaca attatagtaa gaaaatttca ggaggtttca ttatggcaca
    54301 acgttaccaa aatatcatgg tcgcaatcga tggttctaag gaagcggact tggcttttgt
    54361 caagggagtt cattctgctc tacgaaacga cgctaaactc accatcgcac atgtcattga
    54421 cacacgcgct ctccaaagcg tatccacctt tgatgctgaa gtttacgaag aactccaagt
    54481 cgacgctgaa agtctgatga aagagtacga aaaacgtgct aaagatgctg gggtagcaga
    54541 tgttcatatc gtcattgaaa tgggaaatcc aaagaccctg ctagcacgta ctattccaga
    54601 tgccgaggaa gtggacctca tcctcgttgg cgcaactggt ctcaacgcct ttgaacgcct
    54661 cttggtcggc tcttcatctg aatacatact ccgccatgct aaggtcgatt tgctggttgt
    54721 gagagaacaa gaaaaaacct tataatcaca aagaaaagga gcccctagct cctttttgtt
    54781 tacgatttat ttctctcttt atggcgttcg taagccttga gctggcgctg cagttccttt
    54841 ttaatagcag gttctggagc atatttttct tcccaattat ctggttttaa gattttatgg
    54901 gtcactggat caaaatgagc cttgccatct ggaaaaattt tccccatatt ggcctgatgg
    54961 acaatatcaa aaatacgttc tgggtccacc cccatcaaga caaaactgcc gtaggtgaag
    55021 taaagcgtgt caatcaaggc atccacttgc cctatcaaat cttgctgagc aggtgtcttc
    55081 ttggctactt tatctgctgc cttatcaagg gcctgatgaa gttgcgatac agcttgacca
    55141 aaatcttctt cagaaggact ggctgctcga acaaactcca ccaattcttc tattttaaaa
    55201 ccagccctat gggttgcacc ctctaaatcc caagctcgag gttcttcttg ggttcgttca
    55261 tccatcatgt ggtggaaggt cttgacctta ttgaaatgat agtcacggct gacaaagact
    55321 ttttctgaag acaaaacacc aaaatgttcc aaggccttgt ggatcccatc ttgttgattg
    55381 ctagtggtaa tgtgcttggc agcttccttg acactgctac taccatttcc catagcgacc
    55441 gacataccga cgccagccag catttcaagg tcattatctg agtcaccaaa agccatgact
    55501 tgattgaggt caaagccata ttctttccca actcggcgaa tgccttctaa tttagaattt
    55561 ccctgattga tgacatccga tgcaaaagga ttgctacgtg tcaatttcaa gtcttcaaaa
    55621 tcagctgccg ccttctcaga ttcttctggt gtcatcagca tcaaaacttg gtagataggc
    55681 tgattcatca ggtgaagcag gtcctcttcc ttttggggaa caaccttgct gaccatgcga
    55741 ttaaaagact gactcaccgt ccgagttaaa acagagggaa cgaagcgact aattcgttgg
    55801 gaaaaagaac ccagaccaaa ggacatgatt ttagaaccca acatggcatc cttggtccct
    55861 agggcaatct ccgtgccctc ttttttagca tagctaatta gatggcgcaa atgtaacttg
    55921 gaaatagggc tcgtgaacaa gactctgtct ttactaaaga tatactggcc attataggtt
    55981 accgcaaaat ccagatccaa atcgtccatc aattccttaa caaaaaaagg tcctcgccct
    56041 gtcgctacgc caactagtac cccttgttct ttgacaatct taatcgcatc cttagtggat
    56101 ttcaaaacac tcttgcgatt gttgaccaag gttccatcga tatcaaaaaa aacagctttg
    56161 acttccatcc tatcccaatc tccccttttg tgatacaatg attataccac atttcagaaa
    56221 gagttagtaa atcatgccta agaaaatcct tgttttacat acgggtggaa ctatttccat
    56281 gcaggccgat gcttctggcg ctgttgtgac gagttcagat aatcccatga accatgtgtc
    56341 caacccactt gaaggaatcc aagtccacgc cttggacttt tttaaccttc caagtcccca
    56401 tatcaaaccc aaacatatgc tggtcctcta ccagaaaatt aaagaggaag cagataacta
    56461 cgatggagtg gtgatcacac acggaaccga tactttagag gaaacagcct atttccttga
    56521 taccatggaa gttccccaca tgcctatcgt tctaacagga gccatgcgta gctccaatga
    56581 gctcggtagt gatggtgttt ataattacct aagtgcttta cgagtggcca gtgatgacag
    56641 ggctgctgac aaaggagttt tggtcgttat gaacgatgaa atccacgctg ccaagtatgt
    56701 caccaaaaca catacgacta atgtcaacac cttccagact ccaacacatg gccccctcgg
    56761 tctcatcatg aaacaggaaa tcctctactt caaaacagct gaacctcgtg ttcgctttga
    56821 ccttgatcac atacaaggtt tagtccctat catctcggct tatgctggta tgacagatga
    56881 gctgattgat atgctggatt tagaacactt ggacggtttg attatccaag ccttcggagc
    56941 tggtaatatt cccaaagaaa cggctcaaaa attagaaagc cttctgcaaa aaggaatccc
    57001 agtcgctctg gtatcacgat gctttaacgg tattgccgag cctgtttatg cctaccaggg
    57061 tgggggcgta cagttgcaaa aagcaggcgt tttctttgtt aaagaactca acgcccaaaa
    57121 agcccgcttg aaactcctca tcgccctcaa tgccggacta acaggacagg ctttgaaaga
    57181 ctatatggaa ggctaatact cttcgaaaat ctctgcaaac cacgtcacgt cgccttaccg
    57241 tatgtatggt tactgacttc gtcagttcta tctacaacct caaaaacatg ttttgagctg
    57301 acttcgtcag ttctatctgc aacctcaaag cagtgctttg agctgacttc gtcagttcta
    57361 tctacaacct caaaacagtg tgttgcgcag cctttaacca gccgcctagt ccgctctatg
    57421 gtattcatta agtcaacatc tcttgtttaa gagcacaaaa tcaggaaatc ttctcgattc
    57481 cctgattttt tctatttacg ttttcgtgtt gagctacgtt ctgtcaaacc atgaggtaag
    57541 agaacttcac gttcttccaa ctcttcctta tgcataatct tggtcaacat acgcatacta
    57601 atggcaccaa ggtcataaag aggttgggca atcgttgtca agtttggacg ggtaaagcgt
    57661 gagatttgtg aatcatcact agtaataatt tcaaaatctt ctggcacaga aacaccctta
    57721 tcagccaaac cgttcaagac tcctgctgcc aactcatcac ctgtcacaac tgctgcagtt
    57781 gcatttgatg aaatcaaacg ctctgctaag gcgtaaccat catcatagct atatttagat
    57841 tcaaatacca aaccctcact ataagcgatt cctgcttttt tcaaggtttc cttgtagcca
    57901 actaaacgaa ccttaccatt gatgtcatcc actaacggac cgctaacgaa agcaatacgc
    57961 tcattttctt tagcaaggta actcactgca tcaattgttg cttgcttata gtcaatattg
    58021 acacttggca actggtgctc aacatcgaca gttcctgcga gaacaatcgg agtacgtgaa
    58081 cgcgaaaatt ctgagcgaat tttatctgtc aagtgataac ccatatagat aatgccatct
    58141 acctgctttg aaaagagggt attgacaaca gaaacttctt tctcgttatc ttcatcgcta
    58201 ttagctagga caatattgta cttgtacatt tctgcaatat catcaatccc cttagccaaa
    58261 ctcgaaaaat aaccattggt aatatttgga atcacgacac cgacagtggt tgtcttttta
    58321 cttgcaagac cacgcgcaac tgcatttgga cgataatcca agcgatcaat tacctctagc
    58381 acttttttac gggtattctc ttttacattt ttattgccat tgaccacacg gctgaccgtc
    58441 gccatggaaa cacctgcttc acgagcgaca tcataaatgg ttactgtatc atctgcattc
    58501 attccttttc ctgtcctttc tatctcacac attcttttac aagtagaggt actgattgaa
    58561 gctctatatc tacttacaaa agtgaagatg tgaaaatttc gttttcatat ttctacttat
    58621 tccattctat cactaattgt aaacactttc aagtgttttt tgaagattga ttgaaaaaat
    58681 ttcatagaaa acctaggttt agctccttgc taccacctta gactaaacaa aacggaggaa
    58741 actaagccct cctaaagtta tagtaaaatg aaataagaac aggataaatc gatcaggaca
    58801 gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta
    58861 ctataggtat tgttccattc actaccgtca attttagcac atagtcttca tgaaaatatt
    58921 atatcatcat aaccaaccag attcttttgc gatattagct gcctctgttc gattaccagc
    58981 atccaatttt gaaagaatat tggtgacata gtttcgaata gttccgtttg agaggtaaag
    59041 ctgatctgcg atttcttggt tggataagcc ccgggcgatc ccctttaaga cagcaatctc
    59101 ttgttctgtc aacggattgg gacgggtcat caccacttcc atcaattcag gcgaatactc
    59161 cttgcgtcct tcgaggacgg tgtgcaaggt ttgcatgagg tctgcaacgc ttcgttcctt
    59221 taatacataa gcatccactc cagccttgac cgcacgttca aaatacccag cacgcttgaa
    59281 ggtcgtcacc acaaccacct ttgtttcaag cctttctgat cgtatccact ccaagacttc
    59341 aagacctgtc ttaacaggca tttctacgtc aaggatggcg atatctacag actccttttc
    59401 taatagttgg attgcttctt gcccattctt ggcttgaagg acagactcca catctggttg
    59461 aagcgtgagc aattgacaca tggcatctcg caacatactt tgatcttctg cgactaatac
    59521 tttcatctta gtttctctcc ttataaggta gtcgaacttg cacttccgtt ggatgtttct
    59581 gactgattac acttacttct cctgaaaatg gaaaaacacg atctcggatt gtatggagct
    59641 catctccttt tagaaaagca aagccgcagc catcatcact tactgttaaa atgagttcct
    59701 tctctgtccg ttctaatttt aagtaagctt tagacgcttt ggcatgtttg atgatattgg
    59761 tcaccaactc aagcaaaatc atagaagcca ttgactccaa ttcttgagta aggctagcag
    59821 tatctagttg gttatctgtt tccacctcaa ttccagcaat ttctaacatc tttttcacag
    59881 tctctagttc ggatgtcaaa gttctagact taagattttc cacaatggtt cgaacttcac
    59941 gcattgattc tttgctaatt tgctgtattt ctcttaattc cttttccact tgtggataag
    60001 cctgcatttg aaatagctgc aaggctagat ctatcttgac actaagcata gcaaaggtat
    60061 gtcccagact atcatgcaaa tcctgaccga tacgattgcg ctcattttct gctagcaata
    60121 gatttatctg ggtattttgc ttgacctgag cttctttcaa atcctcgaca aggcgaattc
    60181 gaaccgagcc caaagtcatc aaatcgacaa aagtaagaat tacaagcata tagactagaa
    60241 actcaacttc gattctctga aaaatcaaaa gtcgccccac aacaaggact tgagcaagga
    60301 gaaatgtcca tacatgtaaa gactttaaac tacgtacgcc aaaatgataa attaagagat
    60361 tggaaaggaa aaagaaaaac cagatataat tcccagcaac aaaggcggta ttcccagcta
    60421 catagaccag catgagcccc cagaaaagcc aagataggcg ctggttctta gttattaaaa
    60481 cacccaaata cgtcactaca aatagaatat caaccaataa atgccaagca ggaagctccc
    60541 caatcactac aggtaggatg ggaaaaagca taaaaatcaa actggcccaa aacatatagt
    60601 gtatgctttt cagtctttca agcattaagc attctcctta tgaccttgaa ggtaaatagt
    60661 caaaccaaat aaaactgctg aaaaaacaag taaataaact gtggctgata gattgatgcc
    60721 accctcgttt aagaaggtct tgagcaactc catcaattga taggtcggga gacacttacc
    60781 aactgcttgc atccagtctg gaaataaaga aatgggcatc cagagtccgc ctaaaacagc
    60841 caatcctaga taaagaagat tgcccacaac agacatcagc tgactagttg gtaagagagt
    60901 caaggtcaag ccaagtgcta caaaagcaat actccccaca atcagcaaaa tcgcagctcc
    60961 aacccatttt actagaggca tgtctacacc tcttacaaaa tgtccaactg taaaaacaac
    61021 cagaattgag accaaataat caaccagcat acttgttatc tttgatagat aatattctac
    61081 catatttaca gggctatgac gcaatgtttt ctgccagttg ttcatcttat cggtatgtaa
    61141 aacagctgga aatgagagga tagttgtcga catcatggaa aaggcagtca tggaaatgag
    61201 gtaatcacgc ataaaattcg cgagttcacc tggtgtgtcc tgatagatac cagaaaaaaa
    61261 taaatagaaa gccgtcggca tccctaccga caatagataa tagattaatt gtcgtttggt
    61321 caataaaaat tctatcttac taagtgctat ccatcgtttc atcttagtta tctcccttct
    61381 gcgtctcttc aaagattgta ttcaacaaac tacgattatt aacttcgatt tcttgcatcc
    61441 tacatcctgc ttgggctaat agttcccaga aagcatctgc ttctcgagtg actacttgta
    61501 aagaatcttg ctttagggtc cagttttcaa ccaaatttga ctgctctacg acttccttgt
    61561 aagctatagg aaggataaag tgcttttcta tttcctcgct acgcatagct agaggcgtcg
    61621 tatctcgaat caactctccc ttatttaaga gcaaaatgcg gtctgcagtg tgttccactt
    61681 cctcaatata atgggacgaa tagagaatgg tgactccttg cgcttttaac tcctggacaa
    61741 tttcccaaaa acgttgacga gttgaggtat ccatggacgc agtaggctca tctaaaaaaa
    61801 caatctttgg tcgcccaatt aaggtcaaga cgaaagaaaa gagacgcttt tgaccgcctg
    61861 ataatttttc tgccaactgt tctttttgtt gcttgacaaa ctgcaatagt tgatcaattt
    61921 cctgattgct caaaggattt ggatagatac gttgaaagaa agcaatcaac tctttaactt
    61981 ttaatttctg aacgattaca ttttcttgag ggaggtaagc cctagtatag tctaacttag
    62041 aactcgtcac tggtaaacct tgaatagata cttgaccgct tgtgaccagt ttatctccaa
    62101 gcaaacaatc taagagtgtt gtctttccgg caccatttgg accaattaag gcaacacatt
    62161 caccatcgtt gatttcaaag gagatattcc gcaaaatttc cttgtctttt attttcttac
    62221 tcaatttctc aactttaacc accgtcatga gactctcctt tcaaccactc cattcccata
    62281 aggaaaacga cgaaaatcat aaatccaaac cccaaagcac cacgaatgaa ttggcgaagc
    62341 aaggcttgat caaaccaatc agtaaacatt tccactaacc ataccaagag tgacaggccg
    62401 ataaagaaat agatgatccc tctcttcatt cctcaaactc ctttttcaca tctctgacta
    62461 atttcaaacc ttctctaaca agccaagaca tgattccaaa gccagcaaag accttccaag
    62521 gaaaatggta gaaatcctca tccaatcccg aaaacatgag ataggtcata actcctgcta
    62581 ctactaaact tactgcgata atcattttat ttctcatctc ttcttccccc atttcatact
    62641 acaattatag tcttttaaaa tcagaggaga cagaagcttc tgtcactaga aaatatgaca
    62701 aatgtcataa aaaattctgt tcaaaacaag caagatacac tatacaataa aacacaatca
    62761 gaaaaatcta aggcaacttc ctcaaaagag atatcaaacc caattcacac cataatgtaa
    62821 actaatactt atttaaaatc aaaaagagta aaaattttta tcagacaaac acat
//
LOCUS       DAVMCG010000009        52233 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVMCG010000009 DAVMCG010000000
VERSION     DAVMCG010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52233
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.009"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            91..6522
                     /locus_tag="VYP66_000686"
     CDS             91..6522
                     /locus_tag="VYP66_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1850282.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQDPDLFAFNNQGVHAESTSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVS
                     REHFIRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEG
                     KSLFNIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAY
                     DDGTDLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEI
                     KATKYDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKET
                     KSEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQ
                     SVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6814..7160)
                     /locus_tag="VYP66_000687"
                     /pseudo
     CDS             complement(6814..7160)
                     /locus_tag="VYP66_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7317..7603)
                     /locus_tag="VYP66_000688"
                     /pseudo
     CDS             complement(7317..7603)
                     /locus_tag="VYP66_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7631..7858
                     /locus_tag="VYP66_000689"
     CDS             7631..7858
                     /locus_tag="VYP66_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001815354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1850283.1"
                     /translation="MRERLLTQLLLHADETSYRVLESDSQLTYYWTFLSGKVENQAIT
                     LYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            7934..8486
                     /locus_tag="VYP66_000690"
                     /pseudo
     CDS             7934..8486
                     /locus_tag="VYP66_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9069..9545
                     /locus_tag="VYP66_000691"
     CDS             9069..9545
                     /locus_tag="VYP66_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1850284.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            9583..9888
                     /locus_tag="VYP66_000692"
     CDS             9583..9888
                     /locus_tag="VYP66_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1850285.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIESAIKEHGLS"
     gene            9936..11411
                     /locus_tag="VYP66_000693"
     CDS             9936..11411
                     /locus_tag="VYP66_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1850286.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            11437..11514
                     /locus_tag="VYP66_000694"
                     /pseudo
     CDS             11437..11514
                     /locus_tag="VYP66_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            11716..18417
                     /locus_tag="VYP66_000695"
     CDS             11716..18417
                     /locus_tag="VYP66_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1850287.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TQKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLNFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKTLRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSDLPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGYVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(18665..19514)
                     /locus_tag="VYP66_000696"
                     /pseudo
     CDS             complement(18665..19514)
                     /locus_tag="VYP66_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19726..20085)
                     /locus_tag="VYP66_000697"
     CDS             complement(19726..20085)
                     /locus_tag="VYP66_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1850288.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            20177..21133
                     /locus_tag="VYP66_000698"
                     /pseudo
     CDS             20177..21133
                     /locus_tag="VYP66_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            21117..21674
                     /locus_tag="VYP66_000699"
     CDS             21117..21674
                     /locus_tag="VYP66_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1850289.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            21667..21921
                     /locus_tag="VYP66_000700"
     CDS             21667..21921
                     /locus_tag="VYP66_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850290.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            21933..23987
                     /locus_tag="VYP66_000701"
     CDS             21933..23987
                     /locus_tag="VYP66_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1850291.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLIWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHSFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            24171..25031
                     /locus_tag="VYP66_000702"
     CDS             24171..25031
                     /locus_tag="VYP66_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1850292.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            25242..25952
                     /gene="ccdA2"
                     /locus_tag="VYP66_000703"
     CDS             25242..25952
                     /gene="ccdA2"
                     /locus_tag="VYP66_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1850293.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            25972..26538
                     /locus_tag="VYP66_000704"
     CDS             25972..26538
                     /locus_tag="VYP66_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1850294.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            26549..27661
                     /gene="msrB"
                     /locus_tag="VYP66_000705"
     CDS             26549..27661
                     /gene="msrB"
                     /locus_tag="VYP66_000705"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1850295.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            27974..28711
                     /locus_tag="VYP66_000706"
     CDS             27974..28711
                     /locus_tag="VYP66_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850296.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            28708..30399
                     /locus_tag="VYP66_000707"
     CDS             28708..30399
                     /locus_tag="VYP66_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1850297.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIDTGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLNQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            30515..31078
                     /locus_tag="VYP66_000708"
     CDS             30515..31078
                     /locus_tag="VYP66_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1850298.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALTSRPKLIGGARAHYPQDAIRKF"
     gene            31100..36763
                     /locus_tag="VYP66_000709"
     CDS             31100..36763
                     /locus_tag="VYP66_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1850299.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGTMGLVVLPSAGAVDPVATLALASREGVVEMEGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPRKDEQAPVEPENQPEAPEEEKAVEETPKQEESTPDTKAEETVEPKEE
                     TKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDPTKYTDEET
                     VLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPIEGTTVETR
                     EEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAPTITETVIE
                     KPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSIKVALKDNT
                     GTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKEVQLDLKKV
                     EIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLAITNIEEVT
                     EEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDLVDAMQKNP
                     NGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFDRVEGGSIK
                     NINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDKLDDAGIMT
                     NVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIVGHLAHDFN
                     PRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKRGDIFFGSN
                     DMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMGITADTFEV
                     TEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQGNKLTTDS
                     PLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVKQVKEYSVA
                     ELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVNAIKNLYLE
                     ESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGLTYLNRYYG
                     VKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFREVVAKNTLS
                     GNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYRLYEGLNNG
                     QHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRETFKSEINKRAKEQVN
                     YLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPDYAPIREFF
                     GRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETTHVNDRMAY
                     LGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQWYNPDPTKL
                     QTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRPMDRNKLSG
                     PHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTAYVNVNMMA
                     GIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKENNGLLGDDF
                     IIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKTMFDEAVTK
                     DLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            36832..38553
                     /gene="pabB"
                     /locus_tag="VYP66_000710"
     CDS             36832..38553
                     /gene="pabB"
                     /locus_tag="VYP66_000710"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1850300.1"
                     /translation="MHRKTVIDFRTLGERYTFTKPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLNANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            38554..39171
                     /locus_tag="VYP66_000711"
     CDS             38554..39171
                     /locus_tag="VYP66_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1850301.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            39221..40219
                     /locus_tag="VYP66_000712"
     CDS             39221..40219
                     /locus_tag="VYP66_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1850302.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            40346..41305
                     /locus_tag="VYP66_000713"
     CDS             40346..41305
                     /locus_tag="VYP66_000713"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1850303.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            41402..42241
                     /locus_tag="VYP66_000714"
     CDS             41402..42241
                     /locus_tag="VYP66_000714"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1850304.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(42289..42459)
                     /locus_tag="VYP66_000715"
     CDS             complement(42289..42459)
                     /locus_tag="VYP66_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1850305.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            42580..43464
                     /gene="miaA"
                     /locus_tag="VYP66_000716"
     CDS             42580..43464
                     /gene="miaA"
                     /locus_tag="VYP66_000716"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1850306.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVSHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            43457..44695
                     /gene="hflX"
                     /locus_tag="VYP66_000717"
     CDS             43457..44695
                     /gene="hflX"
                     /locus_tag="VYP66_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1850307.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMKELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIAFMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESITFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            44688..45311
                     /locus_tag="VYP66_000718"
     CDS             44688..45311
                     /locus_tag="VYP66_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1850308.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKSFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFPHQLVFEESGKIYMKPVEDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            45326..46255
                     /locus_tag="VYP66_000719"
     CDS             45326..46255
                     /locus_tag="VYP66_000719"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1850309.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQNLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            46276..47031
                     /locus_tag="VYP66_000720"
     CDS             46276..47031
                     /locus_tag="VYP66_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1850310.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(47085..47993)
                     /locus_tag="VYP66_000721"
     CDS             complement(47085..47993)
                     /locus_tag="VYP66_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1850311.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            48057..48326
                     /locus_tag="VYP66_000722"
     CDS             48057..48326
                     /locus_tag="VYP66_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1850312.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            48326..48706
                     /locus_tag="VYP66_000723"
     CDS             48326..48706
                     /locus_tag="VYP66_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1850313.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILRARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            48795..49022
                     /locus_tag="VYP66_000724"
     CDS             48795..49022
                     /locus_tag="VYP66_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850314.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(49062..49787)
                     /locus_tag="VYP66_000725"
     CDS             complement(49062..49787)
                     /locus_tag="VYP66_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEV1850315.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            49949..51790
                     /gene="typA"
                     /locus_tag="VYP66_000726"
     CDS             49949..51790
                     /gene="typA"
                     /locus_tag="VYP66_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1850316.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQETTMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            51810..52064
                     /locus_tag="VYP66_000727"
     CDS             51810..52064
                     /locus_tag="VYP66_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1850317.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        16625 a         9377 c        11341 g        14890 t
ORIGIN      
        1 ataatactta gtaaaacttt ttataacaaa ggctagcaaa gttaaagttt attatctatt
       61 ggaagttaaa taaatatgta aggaattaaa atgaaaaaaa gtacagtatt gtcattaacc
      121 acagctgcag ttattttagc agcctatgcc cctaatgagg tagtcttagc agacacatct
      181 agctctgaag atgctttaaa catctctgat aaagaaaaag tagtattaga taaggaaaca
      241 gaaaataaag agaaacatga agatattcat aatgctatag aaacttcaca ggattttaaa
      301 gagaagaaaa cagcagtcat tgagggaaaa gaagttgtta gtaaaaatcc tgtgacagac
      361 aataacacta gcaatgaaga agcaagaatc aaagaagatt ccaatcaatc ccaaggagat
      421 catacggact catttgtgaa taaaaacaca gaaaatccca aaaaagaaga taaagttgtc
      481 tatattgctg aatttaaaga taaagaatct ggagaaaaag caatcaagca actatccagt
      541 cttaagaata caaaagtttt atatacttat gatagaattt ttaacggtag tgccatagaa
      601 acaactccag ataacttgga caaaattaaa caaatagaag gtatttcatc ggttgaaagg
      661 gcacaaaaag tccaacccat gatgaatcat gccagaaagg aaattggagt tgaggaagct
      721 attgattacc taaagtctat caatgctccg tttgggaaaa attttgatgg tagaggtatg
      781 gtcatttcaa atatcgatac tggaacagat tatagacata aggctatgag aatcgatgat
      841 gatgccaaag cctcaatgag atttaaaaaa gaagacttaa aaggaactga taaaaattat
      901 tggttgagtg ataaaatccc tcatgcgttc aattattata atggtggcaa aatcactgta
      961 gaaaaatatg atgatggaag agattatttt gacccacatg ggatgcatat tgcagggatt
     1021 cttgctggaa atgatactga acaagatatc aaaaacttta acggcataga tggaattgca
     1081 cctaatgcac aaattttctc ttacaaaatg tattctgacg caggatctgg gtttgcgggt
     1141 gatgaaacaa tgtttcatgc tattgaagat tctatcaaac acaacgttga tgttgtttcg
     1201 gtatcatctg gttttacagg aacaggtctt gtaggtgaga aatattggca agctattcgg
     1261 gcattaagaa aagcaggcat tccaatggtt gtcgctacgg gtaactatgc gacttctgct
     1321 tcaagttctt catgggattt agtagcaaat aatcatctga aaatgaccga cactggaaat
     1381 gtaacacgaa ctgcagcaca tgaagatgcg atagcggtcg cttctgctaa aaatcaaaca
     1441 gttgagtttg ataaggttaa cattggagga caaagtttta aatacagaaa tataggggcc
     1501 tttttcgata agaataaaat cacaacaaat gaagatggaa caaaagctcc tagtaaatta
     1561 aaatttgtat atataggcaa ggggcaagac caagatttga taggtttgga tcttaggggc
     1621 aaaattgcag taatggatag aatttataca aaggatttaa aaaatgcttt taaaaaagct
     1681 atggataagg gtgcacgcgc cattatggtt gtaaatactg taaattacta caatagagat
     1741 aattggacag agcttccagc tatgggatat gaagcggatg aaggtactaa aagtcaagtg
     1801 ttttcaattt caggagatga tggtgtaaag ctatggaaca tgattaatcc tgataaaaaa
     1861 actgaagtca aaagaaataa taaagaagat tttaaagata aattggagca atactatcca
     1921 attgatatgg aaagttttaa ttccaacaaa ccgaatgtag gtgacgaaaa agagattgac
     1981 tttaagtttg cacctgacac agacaaagaa ctctataaag aagatatcat cgttccagca
     2041 ggatccacat cttgggggcc aagaatagat ttacttttaa aacccgatgt ttcagcacct
     2101 ggtaaaaata ttaaatccac gcttaatgtt attaatggca aatcaactta tggctatatg
     2161 tccggaacta gtatggcgac tccaatcgta gcagcttcta ctgttttgat tcgaccaaaa
     2221 ttgaaggaaa tgcttgaaaa acccgtatta aaaaatctta aaggtgatga taaaatagac
     2281 cttacaagtc ttacaaaaat agccctacaa aatactgcaa gacctatgat ggatgcaact
     2341 tcttggaaag aaaaaagtca atactttgca tcacctagac agcagggggc ggggctaatt
     2401 aatgtggcca acgctttgag aaatgaagtt gtagcgactt tcaaaaacac ggattctaaa
     2461 ggtttggtaa attcatatgg ttccatttct cttaaagaaa taaaaggtga taaaaaatac
     2521 tttacaatta agcttcacaa tacatccaac aggcctttaa cctttaaagt ttcagcatca
     2581 gcggtaacta cagattctct aactgacaga ctaaaactgg atgaaacata taaagatgaa
     2641 aaatctccag atggtaagca aattgttcca gaaattcatc cagaaaaagt caaaggggca
     2701 aatattacat ttgagcatga cactttcact ataggggcaa attctagctt tgatttaaat
     2761 gcggttataa atgttgggga ggctaaaaat aaaaataaat ttgtagaatc atttattcat
     2821 tttgagtcag tagaagaaat ggaagcatta agctccaatg gcaagaaaac cgacttccaa
     2881 ccatctttat caatgcccct aatgggattt gctgggaatt ggaaccacga accaatcctt
     2941 gataaatggg cttgggaaga aggatcaaaa tcaaaaacaa tggaaggtta tgatgatgac
     3001 ggtaaaccaa aaattccagg aaccttaaat aaggggattg gtggagaaca tggtatagat
     3061 aaatttaatc cagcaggagt tatccaaaat agaaaagata aaaatacaac atctctagat
     3121 caagatccag acttatttgc ctttaacaac caaggtgttc atgcagaatc cactagtggt
     3181 tctaagattg ctaacattta tcctttagat tcaaatggaa atcctcaaga tgctcaacta
     3241 gaaagaggac taactccatc tccacttgtt ctaagaagtg cagaagaagg actaatttca
     3301 attgtaaaca ccaacaaaga aggagaaaac caaaaagacc ttaaagttgt atcaagagag
     3361 cacttcataa gaggaattct aaattctaag ggaaatgacg ctaagggtat caaatcatcc
     3421 aaactaaaag tttggggtga cttgaaatgg gatggactca tctataaccc aagaggtaga
     3481 gaagaaaatg ccccagaaag taaggataac caagatccag ctactaagat acgaggacaa
     3541 tttgaaccga ttgcggaagg tcaatatttc tataaattta aatatagatt aactaaagat
     3601 tacccatggc aggtttccta tattcctgta aaaattgata acacagcccc taagattgtt
     3661 tcggttgatt tttcaaatcc tgaaaaaatt aagctaatca caaaggatac ttatcacaag
     3721 gtaaaagatc aatacaagaa tgaaacttta tttgctagag atcaaaaaga acatcctgaa
     3781 aaatttgatg agattgcaaa tgaggtgtgg tatgcaggag ctgctcttgt taatgaagat
     3841 ggagaggttg agaaaaatct tgaagtaact tatgcaggtg agggtcaagg aagaaatagg
     3901 aagcttgata aagatgggaa tactatctat gaaattagcg gagcaggaga tctaagagga
     3961 aaaatcatcg aagtaatcgc cctagatgga gcaagcaact ttaccaaaat ccataggatt
     4021 aaatttgcta atcaagctga tgaaaaaggg atgatttcct attatctagt agatcctgat
     4081 caggattcat ctaaatacca aaagcttggc gaaattcctg aatctaaatt taagaattta
     4141 aaaaatgtta aagatgatag cctaaacaaa gagacagctg aggtggaaaa taacctttta
     4201 gtagataatc agtctatcga aggaaaatct ctctttaata ttcataaaac tatttcaaca
     4261 attagagact ttgaaaataa agacctaaag aaactcatta aaaagaaata taagcaagaa
     4321 gacgactttg taaatggtgg aacaagaaca gtagagcgtg attataaata cgatgataaa
     4381 ggaaatataa tagcctacga tgatgggact gatctagaat atgaaactga gaaacttgac
     4441 gaaatcaaat caaaaattta tggtgttcta agtccgtcta aagatggaca ctttgaaatt
     4501 cttggaaaga taagcaatgt ttctaaaaat gccaaggtat attatgggaa taactataaa
     4561 tctatagaaa tcaaagcgac caagtatgat ttccactcaa aaacgatgac atttgatcta
     4621 tacgctaata ttaatgatat tgtggatgga ttagcttttg caggagatat gagattattt
     4681 gttaaagata atgatcagaa aaaagctgaa attaaaatta gaatgcctga aaaaattaag
     4741 gaaactaaat cagaatatcc ctatgtatca agttatggga atgtcataga attaggggaa
     4801 ggagatcttt caaaaaacaa accagacaat ttaactaaaa tggaatctgg taaaatctat
     4861 tctgattcag aaaaacaaca atatctgtta aaggataata tcattctaag aaaaggctat
     4921 gcactaaaag tgactaccta taatcctgga aaaacggata tgttagaagg aaatggagtc
     4981 tatagcaagg aagatatagc aaaaatacaa aaggccaatc ctaatctaag agccctttca
     5041 gaaacaacaa tttatgctga tagtagaaat gttgaagatg gaagaagtac ccaatctgta
     5101 ttaatgtcgg ctttggacgg ctttaacatt ataaggtatc aagtgtttac atttaaaatg
     5161 aacgataaag gggaagctat cgataaagac ggaaatcttg tgacagattc ttctaaactt
     5221 gtattatttg gtaaggatga taaagaatac actggagagg ataagtccaa tgtagaagct
     5281 ataaaagaag atggctccat gttatttatt gataccaaac cagtaaacct ttcaatggat
     5341 aagaactact ttaatccatc taaatctaat aaaatttatg tacgaaatcc agaattttat
     5401 ttaagaggta agatttctga taagggtggt tttaactggg aattgagagt taatgaatcg
     5461 gttgtagata attatttaat ctacggagat ttacacattg ataacactag agattttaat
     5521 attaagttga atgttaaaga cggtgacatc atggactggg gaatgaaaga ctataaagca
     5581 aacggatttc cagataaggt aacagatatg gatggaaatg tttatcttca aactggctat
     5641 agcgatttga atgctaaagc agttggagtc cactatcagt ttttatatga taatgttaaa
     5701 cccgaagtaa acattgatcc taagggaaat actagtatcg aatatgctga tggaaaatct
     5761 gtagtcttta acatcaatga taaaagaaat aatggattcg atggtgagat tcaagaacaa
     5821 catatttatg taaatggaaa agaatataca tcatttgatg atattaaaca aataacagac
     5881 aagacactaa acattaagat tgttgtaaaa gattttgcaa gaaatacaac cgtaaaagaa
     5941 ttcattttaa ataaagatac gggagaggta agtgaattaa aacctcatag ggtaactgtg
     6001 accattcaaa atggaaaaga aatgagttca acgatagtgt cggaagaaga ttttatttta
     6061 cctgtctata agggtgaatt agaaaaagga taccaatttg atggttggga aatttctggt
     6121 ttcgaaggta aaaaagacgc tggctatgtt attaatctat caaaagatac ctttataaaa
     6181 cctgtattca agaaaataga ggagaaaaag gaggaagaaa ataaacctac ttttgatgta
     6241 tcgaaaaaga aagataaccc acaagtaaac catagtcaat taaatgaaag tcacagaaaa
     6301 gaggatttac aaagagaaga tcattcacaa aaatctgatt caactaagga tgttacagct
     6361 acagttcttg ataaaaacaa tatcagtagt aaatcaacta ctaacaatcc taataagttg
     6421 ccaaaaactg gaacagcaag cggagcccag acactattag ctgccggaat aatgtttata
     6481 gtaggaattt ttcttggatt gaagaaaaaa aatcaagatt aagataaaag ctatagaaaa
     6541 aaatggttta tgtactgaga ttagatagtg aggtgatgac atagttttgt gaaaacagcc
     6601 atttataact caattattta gtttacttca ctattgatac tatttggagt tattaatgga
     6661 cttagtttag ataactaatg aattgattga aagggttagt attgacaata ttggtcatat
     6721 tgattagaaa atagagtcta tcaaaattta aaggctaata gaggtgatga gacaatttcg
     6781 gctctttgtc aactgtagtg ggttgaagaa aagctaagct cgagaaagga caaattttgt
     6841 cctttctttt ttgatattca gagcgatgaa aatccgtttt ttgaagtttt caaagtttcg
     6901 aaaaccaaag gcattgcgct tgataagttt gatgagatta ttggtcgttt ccagtttggc
     6961 attagaatag tgtagttgaa gggcattgac aatcttctct ttatctttga ggaaggtttt
     7021 agaggatgaa cctgattcag attgtcctca atgagtccga aaaatttgtc aggctcctta
     7081 ttctgaaagt gaaaaagcaa gagttgatag agattatagt ggtgtttcaa gtcttctgaa
     7141 tagctcaaaa gtttatctat agtagattga aactagaata gtacacatct gcttctaaaa
     7201 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctggtcttat ttcatttcat
     7261 tataaattca tcagaaagtc gtgatttcta ttgaaatgag gactttcttt ttacactcat
     7321 ctgctttcaa aaagcattct agtccatctc cgattaacga tggactttat cacctccttc
     7381 tccagtcctt gtatgacatc ttccaaagtt cgaaaggctt tattcttaaa tccacgttta
     7441 cgaatctctt tccacacttg ttcaatgggg ttcatctctg gtgtgtatgg aggaataaat
     7501 gcaaaaccaa tattagtcgg aatctttaag gtacttgatt tatgccatat agcattgtcc
     7561 ataagagtaa aagataatca tctggataag cttatgaaag ctcctattcc taaagcccct
     7621 ttataacctc ttgcgagaga gactattgac tcagctctta cttcatgcag atgaaacctc
     7681 ttatcgggtc ttagaaagtg atagtcagct gacctactat tggacttttt tgtcagggaa
     7741 agttgagaat caagcaatca cgctgtacca ccatgatcag cgtcggagtg gtttagtagt
     7801 acaagaattc ctaggagatt attctggcta tgtgcattgt gatatgttgc ggcagtaact
     7861 taggacttta gtcctctagt tctgcctatg cgatagcagt ccaaggttta ggagcaaggc
     7921 gacgctaagc ttggtaaact gcgagccgct agaagcttat cgtcaactgg cagaagctga
     7981 acttgttgga tgttgggcgc atgtgagaag gaaatttttt gaagcgaccc ccaagcaagc
     8041 agataaatca tccttaggag ctaaaggttt agcctattgt gaccagttat ttgccttgga
     8101 aagagactgg gaggctttgc cagctgatga acgactacag aaacgtcaag aagagctcca
     8161 acccctaatg gaagatttct ttgcttggtg ccggcgtcag tcagttttag caggttcaaa
     8221 actaggaagg gcaattgaat acagcctcaa gtataaagaa acctttaaga ctattttgaa
     8281 agacggacat ctggtccttt ccaataatct agctgaacgc gccattaaat cattggttat
     8341 gggacggagt aaaagagtcc agtggactct tttagcctaa gctaaatttt aaaaagcgag
     8401 ggtggttatt ttctcaaagt tttgaaggag ctaaagcaag agctattatt atgagtttgt
     8461 tggaaacagc taaacgtcat caattatagt gcgttgaatc tataacagta cgcatcgact
     8521 gctaaaatat ttctataaat caattttcct ttcctaatcg atttgtgcat atcttatttc
     8581 aatccattat aaatagcgag aaatatctat cctatcttct agaatgtctt ctaaacgtgg
     8641 aaactctcgt aaacaaagag gttttagagg cttatttact atggactaaa gttgtacaag
     8701 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact aatctggaga
     8761 tttttcaata gacttcgtta ttggacggtt acgatatgat cactgacttc gtcagttcta
     8821 tctacaacct aaaaacagtg ttttgaacaa cctgcggcta gcttcctagt ttgctctttg
     8881 attttcattg aatattagaa cagcaaaaat gcttgaagta tttgtttgtg tttttatttt
     8941 tatataacaa actataaaca aaacaaaaat ataaaaaaag agacaaaaaa gaacagaaag
     9001 taattgacaa cggtttcata tagtgttata cttatggcat aaagttaatg gaaagaaggg
     9061 aaaaacttat ggtattagat tatttctttg acaaaaacct tgtgttttgc ttagaagcgg
     9121 ataatcaaga acaactcttt gatcaggttg caactttatt ggaagaacga gaaattgtca
     9181 ctccaactta tcgtgaagcc ttgatcacgc gtgaaaagtc atttccaact ggtttagata
     9241 tggaatttct aggaaaggac ttgccaaatg tagcgattcc tcatacagat attgttcata
     9301 atctagctga gaaagtggtg gttgttcgat tagaaaaacc agtaactttt cacaatatga
     9361 tagctcctga taaggaagta gaagtatccc tactcttctt tattattaac aattcaagtt
     9421 caagtcaaac aaatattctg gctcagttga tggacttttt cacaggaaat ggacatcttg
     9481 aagatttatc aaaaatttcc gaaccagaaa aactttatgc ttacattgct gaagcaaccg
     9541 cttaatcttg tctattaaaa aataaaatcg gaggaaatcc aaatgattaa aattcttgct
     9601 gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa gtgctctaga agaagaactt
     9661 tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg tgaaagatgt aaacgaagac
     9721 cttatgaaag gttacgatat ctttacacca atcgctgcaa cagaccttgg ttttgaacca
     9781 ggtatcccag ttatcgaagc tgggccaatc ttattccgta taccagcaat gagcgctcca
     9841 gtatttgaca atattgaatc agctattaaa gaacacggat taagctaatt ctaatttgtt
     9901 aacattcata taacataaaa aagggaggaa ctgttatgga tgcaatcttt gacctaatcg
     9961 gaaaggtttt caatcccatc ttagaaatgg gtggacctgt catcatgtta atcattttga
    10021 cagtattggc tttacttttt ggagtgaaat tctccaaagc gcttgaaggt ggtatcaaac
    10081 ttgccatcgc tcttacaggt atcggtgcta tcatcggtat gctaaatggt gctttctcag
    10141 catcacttgc aaaattcgtt gaaaacactg gtatccaatt gagtattacc gacgttggtt
    10201 gggcaccact cgcaacaatc acttggggtt ctgcttggac actatacttc ttgctcatca
    10261 tgttgattgt caacgtagtg atgcttgcta tgaagaaaac cgatacactt gatgtcgata
    10321 tctttgatat ctggcacttg tctatcacag gtctcttgat taaatggtat gctgataaca
    10381 atggtgtgag tcaaggggtt tcactcttta ttgctacagc agctatcgtc cttgtcggtg
    10441 tgttgaaaat tatcaactct gacttgatga aacctacatt tgatgacctt cttaacgccc
    10501 caagttcatc accaatgaca tcaactcaca tgaactacat gatgaaccca gttatcatgg
    10561 ttttggataa gatttttgaa aaattcttcc caggccttga taaatatgac tttgatgctg
    10621 ctaaattgaa caagaaaatc ggtttctggg gatctaaatt cttcatcggt ttcatccttg
    10681 gtatcgttat cggtattatg ggaactccac atccaattgc aggtgttgca gatgcagata
    10741 aatggcgtct tgttatcaaa ggatggttgt ctcttggttt gactgccggt gtatctttgg
    10801 aactcttctc acttatcggt tcatggttca tcgcagccgt agaaccacta tcacaaggta
    10861 ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt caatatcggt cttgactggc
    10921 cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa cgtacttgca ccaatcatgt
    10981 tgattgaagc agtgcttctt tcaaaagttg gaaatggtat cttgccactt gcaggtatca
    11041 tcgctatggg tgttactcca gctctcttgg ttgtaactcg tggtaaattg ctccgtatga
    11101 ttatcttcgg aacactcttg ttgccactct tccttctttc aggtacactt attgcaccat
    11161 ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga aggtgtgagc caaactcaat
    11221 tgattactca ctctactctt gaaggaccaa tcgaaaaact tcttggttgg acaattggta
    11281 acactacaac tggtgatatc aaagcaatcc ttggtgcagt agccttcctt gtattctata
    11341 tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg taacgaagag tacgcagcaa
    11401 aagcaaaata atgcgctcct ataaaatata aactcaatga aaatcaaaga gcaaactagg
    11461 aagctagccg caggttgctc aaaacacagt tttgaggttg tagataagac tgacgaagtc
    11521 agctcaaaac atggttttga ggttgtagat gaaactgacg aagtcagtaa tcatacatac
    11581 ggcaaggcga cactgacgaa gtttgaattg gattttcgca gagtgtaaat tgttgaaact
    11641 aggttgtcat accatgtata ccacttgggc tttggcagta gctaactgca ctaaatataa
    11701 tataaggagg gttttatggg gaaaggccat tggaatcgga aaagagttta tagcattcgt
    11761 aagtttgctg tgggagcttg ctcagtaatg attgggactt gtgcagttct attaggagga
    11821 aatatagctg gagaatctgt agtttatgcg gatgaaacac ttattactca tactgctgag
    11881 aaacctaaag aggaaaaaat gatagtagaa gaaaaggctg ataaagcttt ggaaactaaa
    11941 aatgtagttg aaaggacaga acaaagtgaa cctagttcaa ctgaggctat tgcatctgag
    12001 aagaaagaag atgaagccgt aactcaaaaa gaggaaaaag tgtctgctaa accggaagaa
    12061 aaagctccaa ggatagaatc acaagcttca agtcaagaaa aaccgctcaa ggaagatgct
    12121 aaagctgtaa caaatgaaga agtgaatcaa atgattgaag acaggaaagt ggattttaat
    12181 caaaattggt actttaaact caatgcaaat tctaaggaag ccattaaacc tgatgcagac
    12241 gtatctacgt ggaaaaaatt agatttaccg tatgactgga gtatctttaa cgatttcgat
    12301 catgaatctc ctgcacaaaa tgaaggtgga cagctcaacg gtggggaagc ttggtatcgc
    12361 aagactttca aactagatga aaaagacctc aagaaaaatg ttcgccttaa ttttgatggc
    12421 gtctacatgg attctcaagt ttatgtcaat ggtcagttag tggggcatta tccaaatggt
    12481 tataaccagt tctcatacga tatcaccaaa taccttcaca aagatggtcg tgagaatgtg
    12541 attgctgtcc atgcagtcaa caaacagcca agtagccgtt ggtattcagg aagtggtatc
    12601 tatcgtgatg tgactttaca agtgacagat aaggtgcatg ttgagaaaaa tgggacaact
    12661 attttaacac caaaacttga agaacaacaa catggcaagg ttgaaactca tgtgaccagc
    12721 aaaatcgtca atacggacga caaagaccat gaacttgtag ccgaatatca aatcgttgaa
    12781 cgaggtggtc atgctgtaac aggcttagtt cgtacagcga gtcgtacctt aaaagcacat
    12841 gaatcaacaa gcctagatgc gattttagaa gttgaaagac caaaactctg gaccgtttta
    12901 aatgacaaac ctgccttgta cgaattgatt acgcgtgttt accgtgacgg tcaattggtt
    12961 gatgctaaga aggatttgtt tggttaccgt tactatcact ggactccaaa tgaaggtttc
    13021 tctttgaatg gtgaacgtat taaattccat ggagtatcct tgcaccacga ccatggggcg
    13081 cttggagcag aagaaaacta taaagcagaa tatcgccgtc tcaaacaaat gaaggagatg
    13141 ggagttaact ccatccgtac aacccacaac cctgctagtg agcaaacctt gcaaatcgca
    13201 gcagaactag gtttactcgt tcaggaagag gcctttgata cttggtatgg tggcaagaaa
    13261 ccttatgact atggacgttt ctttgaaaaa gatgccactc acccagaagc tcgaaaaggt
    13321 gaaaaatggt ctgattttga cctacgtacc atggtcgaaa gaggcaaaaa caaccctgct
    13381 atcttcatgt ggtcaattgg taatgaaata ggtgaagcta atggtgatgc ccactcttta
    13441 gcaactgtta aacgtttggt caaggttatc aaggatgttg ataagactcg ctatgttacc
    13501 atgggagcag ataaattccg tttcggtaat ggtagcggag ggcatgagaa aattgctgat
    13561 gaactcgatg ctgttggatt taactattct gaagataatt acaaaaccct tagagctaag
    13621 catcccaaat ggttgattta tggatcagaa acatcttcag ctacccgtac acgtggaagt
    13681 tactatcgcc ctgaacgtga attgaaacat agcaatggac ctgagcgtaa ttatgaacag
    13741 tcagattatg gaaatgatcg tgttggttgg gggaaaacag caaccgcttc atggactttt
    13801 gaccgtgaca acgctggcta tgctggacag tttatctgga caggtacgga ctatattggt
    13861 gaacctacac catggcacaa ccaaaatcaa actcctgtta agagctctta ctttggtatc
    13921 gtagatacag ccggcattcc aaaacatgac ttctatctct accaaagtca atgggtttct
    13981 gttaagaaga aaccgatggt acaccttctt cctcactgga actgggaaaa caaagaatta
    14041 gcatccaaag tagctgactc agaaggtaag attccagttc gtgcttattc gaatgcttct
    14101 agtgtagaat tgttcttgaa tggaaaatct cttggtctta agactttcaa taaaaaacaa
    14161 accagcgatg ggcggactta ccaagaaggt gcaaatgcta atgaacttta tcttgaatgg
    14221 aaagttgcct atcaaccagg taccttggaa gcaattgctc gtgatgaatc tggcaaggaa
    14281 attgctcgag ataagattac gactgctggt aagccagcgg cagttcgtct tattaaggaa
    14341 gaccatgcga ttgcagcaga tggaaaagac ttgacttaca tctactatga aattgttgac
    14401 agccagggga atgtggttcc aactgctaat aatctggttc gcttccaatt gcatggccaa
    14461 ggtcaactgg tcggtgtaga taacggagaa caagccagcc gtgaacgcta taaggcgcaa
    14521 gcagatggtt cttggattcg taaagcattt aatggtaaag gtgttgccat tgtcaaatca
    14581 actgaacaag cagggaaatt cacccttact gcccactctg atctcttgaa atcgaaccaa
    14641 gtcactgtct ttactggtaa gaaagaagga caagagaaga ctgttttggg gacagaagtg
    14701 ccaaaagtac agaccattat tggagaggca cctgaaatgc ctaccactgt tccgtttgta
    14761 tacagtgatg gtagccgtgc agaacgtcct gtaacctggt cttcagtaga tgtgagcaag
    14821 cctggtattg taacggtgaa aggtatggct gacggacgag aagtagaagc tcatgtcaag
    14881 gttctagcaa ttgcgaaaga attaccaaca gttaaacgta ttgctccaaa tactgacttg
    14941 aattctgtag acaaatctgt ttcttatgtt ttgactgatg gaagtgtaca agagtacgaa
    15001 gtagatagct gggagattac ggaagtagat aaagccaaac tttcagtagc tggatcacgt
    15061 attcaaatga ctggtcagtt agctggagaa actattcatg caacccttgt ggtagaagaa
    15121 ggaaatgctg cagcacctgt agtgccaact gttactgttg gaggtgaagc agtaacaggt
    15181 cttactagtc gacaaccaat gcaatatcgt actctatctt atggtgccca attgccagaa
    15241 gtcacagcaa gtgctgaaaa tgctgatgtg acagttcttc aagcaagcgc agcaaacggc
    15301 atgcgtgcga gcatctttat tcagcctaaa gatggtggcc ctcttcaaac ctatgcaatt
    15361 caattccttg aagaagcgcc aaaaattgct cacttgagtt tgcaagtgga aaaagctgac
    15421 agtctcaaag aagaccaaac tgtcaaattg tcggttcgag ctcactatca agatggaacg
    15481 caagctgtat taccagctga taaagtaacc ttctctacaa gtggtgaagg ggaagtcgca
    15541 attcgtaaag gaatgcttga gttgcataag ccaggagcag tcactctgaa cgctgaatat
    15601 gagggagcta aaggccaagt tgaactcact atccaagcca atactgagaa gaagattgcg
    15661 caatctatcc gtcctgtaaa tgtagtcaca gatttgcatc aaaaacctac tcttccaaca
    15721 acagtaacgg ttgagtatga caaaggtttc cctaaagctc acaaagtcac ttggcaagct
    15781 attccgaaag aaaaactaga ctcctatcaa acatttgaag tactaggtaa agttgaagga
    15841 attgaccttg aagcgcgtgc aaaagtctct gtagaaggta tcgtttcagt tgaagaagtc
    15901 agtgtgacaa ctccaatcgc agaagcacca caattaccag aaagtgttcg gacatatgat
    15961 tcaaatggtc acgtttcatc agctaaggtt gcatgggatg cgattcgtcc agagcaatac
    16021 gctaaggaag gtgtctttac agttaatggt cgcttagaag gtactcaatt aacaactaaa
    16081 cttcatgttc gcgtatctgc tcaaactgag caaggtgcaa acatttctga ccaatggacc
    16141 ggttcagact tgccacttgc ctttgcttca gactcaaatc caagcgaccc agtttcaaat
    16201 gttaatgaca agctcatttc ctacaataac caaccagcca atcgttggac aaactggaat
    16261 cgtactaatc cagaagcttc agtcggtgtc ctattcggag attcaggtat tttgagcaaa
    16321 cgttcagttg ataacttaag cgttggcttc catgaagacc atggagttgg tgcaccgaag
    16381 tcttatgtga ttgagtatta tgttggtaag actgtcccaa cagctcctaa aaaccctagt
    16441 tttgttggta atgaggacca tgtctttaat gattctgcca actggaaacc agttactaat
    16501 ctaaaagccc ctgctcaact caaggctgga gaaatgaacc actttagctt tgataaagtt
    16561 gaaacctatg ctgttcgtat tcgcatggtg agagcagaca acaaactagg aacgtctatc
    16621 acagaggtac aaatctttgc gaaacaagtt gcggcagcca agcaaggaca aacaagaatc
    16681 caagttgacg gtaaagactt agcaaacttc aaccctgatc tgacagacta ctaccttgag
    16741 tctgtagatg gaaaagttcc ggcagtcaca gcaagtgtta gcaacaatgg tctcgctacc
    16801 gtcgttccaa gcgttcgtga aggtgagcca gttcgtgtca tcgcgaaagc tgaaaatggc
    16861 gacatcttag gagaataccg tctgcacttc actaaggata agaacttact ttctcataaa
    16921 ccagttgctg cggttaaaca agctcgcttg ctacaagtag gtcaagcact tgaattgccg
    16981 actaaggttc cagtttactt cacaggtaaa gacggctacg aaacaaaaga tttgtcagtt
    17041 gaatgggaag aagttccagc agaaaatctg acaaaagcag gtcaatttac cgttcgaggc
    17101 tatgtccttg gtagtgatct tgttgctgag gtcactgtac gagtgacaga caaactaggc
    17161 gaagctcttt cagataaccc taactatgat gaaaacagta accaggcctt tgcttcagca
    17221 accaatgata ttgacaaaaa ctctcatgac cgcgttgact atctcaatga cggagatcat
    17281 tcagaaaatc gtcgttggac aaactggtct ccaacaccat cttctaatcc agaagtatca
    17341 gcgggtgtga tcttccgtga aaatggtaag attgtagaac ggactgttgc gcaagccaaa
    17401 cttcacttct ttgcagatag tggtacggat gcaccaacta aactcgtttt agaacgctat
    17461 gtcggtccag agtttgaagt gccaacctac tattcaaact accaagccta cgacgcagac
    17521 catccattca acaatccaga aaattgggaa gctgtgcctt atcgtgcgga taaagacatc
    17581 gcagctggtg atgaaatcaa cgtaacattt aaagctgtca aagccaaagc tatgagatgg
    17641 cgtatggagc gtaaagcaga taagagcggt gttgcgatga ttgagatgac cttccttgca
    17701 ccaagtgaat tgcctcaaga aagtacgcaa tcgaagattc ttgtagatgg aaaagaactt
    17761 gctgatttcg ctgaaaatcg tcaagactat caaattacct ataaaggtca acggccaaaa
    17821 gtctcagttg aagaaaacaa tcaagtagct tcaactgtgg tagatagtgg agaagatagc
    17881 cttccagtac ttgttcgcct cgtttcagaa agtggaaaac aagtcaagga ataccgtatc
    17941 cacttgacta aggaaaaacc agtttctgag aagacagttg ctgctgtaca agaagatctt
    18001 ccaaaactcg aatttgttga aaaagatttg gcctacaaga cagttgagaa aaaagattca
    18061 acactgtatc taggtgaaac tcgtgtagaa caagaaggaa aaactggtaa agaacgtatc
    18121 tttacagcga ttaatcctga tggaagtaag gaagaaaaac tccgtgaagt ggtagaagct
    18181 ccgacagacc gcatcgtctt ggttggaacc aaaccagtag ctcaagaagc taaaaaacca
    18241 caagtgtcag aaaaagcaga tacaaaacca attgattcaa gtgaagctag tcaaactaat
    18301 aaagcccagt taccaaatac aggtagtgcg tcaagccaag cagcagtagc agcaggttta
    18361 gctcttctag gtttgagtgc aggattagta gttactaaag gtaaaaaaga agactagaaa
    18421 ttttgatacc ttctttatca ttaaagacca aagaaaaact cttgtcctaa atagaagata
    18481 aagagtctgg aacaaaatag ttctcaacca caaaaaagct agatatttcc aattgtggaa
    18541 ctctagcttt ttaattttga gtcattctct tattgtatag tggattgaaa ctagaatagt
    18601 acacttctac ttctaaaaca ttgttagaaa tcgatttgac tgtccttatc gatttgtcct
    18661 gttcttattt cattttacta tattttagga ggttattggc cataagtacc aatcccatgt
    18721 caattctcac ttgcccctca gattacatct cttgtaaccc aaagaagcct ttatctgccc
    18781 aaagacaggt tccacatcaa tcttgcgttg agcgaaaatc tgtctacctt ggggagataa
    18841 aagcgcctga cattctttag ctttcaagtt ttgatagcgt tcgttcatat atagtccctt
    18901 ttgaggggct gattcaggtt cgtcggcgta gtaaaccttg atttcctgtt gaaagtctgt
    18961 ctgtgttttc tgatgtttgg tatggtgaaa acgataatac cagccatcag gatgtgtgta
    19021 gctatcctcc ttgtcattat agtgccaatt cgctaagttt ttagctgact ctttataccc
    19081 tctcttttgt ttcttatcaa acatggcata tttaatcagg aggggagtga tttcttcttg
    19141 aaaatagact tgtatctgtt cttgaagttt ggcggagaat ttctctgtcg ttttcttcca
    19201 cacaaaacta tacttgttgg cattggcttc aatcttagtt ccgtcaataa acaaacaatc
    19261 taaggtcact aactcttcca tttttcaatt tttcgaccag agaaaatccc ttgtgaatag
    19321 gcaaatagaa gagtagatac aagcatttta aggtgataag acaggcgatc aaaggcatga
    19381 tagaaggcgt ggaaatgaca atcctccaag gtattcacca ctttttcaat agtaaaaacg
    19441 agatggtctt gtggcaagaa ggaactgatt tctagtggta aagttgtttg atttgtgtta
    19501 tagtgaatat gcatggaata gcctttctaa atggtttatt gggcaattct attttaccaa
    19561 gactatcgta accatgcaaa aaaagcaacg gcaaatccgt tgcttttttt ggagataaga
    19621 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
    19681 tttgtagaga aagaaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
    19741 caattcaaca atcatttcta catacatgat aagggttaat aagaatcctg cacgccagaa
    19801 gaatttgatg aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
    19861 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
    19921 tttagctgta atcaggtaat attcaaatac caagaccgga aaagccaaat ccgcaaagtt
    19981 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
    20041 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
    20101 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
    20161 ggtgattttt gttataatga aagtcatgaa atcttataat accttgaatg attattatcg
    20221 aaaattcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
    20281 tcgtgatgga actgtggatc atggaggctg tactttttgt acggtttcag gttctggaga
    20341 tgctattgta gccccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
    20401 gcaccgtaag tggccggatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
    20461 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
    20521 ggtaggtatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
    20581 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaga ccacttatga
    20641 agcaacctct gacctgatta accgtgtgca ttcttatgaa ttgtaggtgg aaacggtcaa
    20701 gcgtttgaga aagtatccca agattgagat tgtttcccat ttgatcaatg gcttgcctgg
    20761 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
    20821 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
    20881 tgagggacgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
    20941 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
    21001 gctgattggt cctatgtgga gcctcaaaaa atgggaagtc ctcaacagca ttgagatgga
    21061 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
    21121 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
    21181 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
    21241 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
    21301 aggctggctt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
    21361 tgacaaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
    21421 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
    21481 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgac ctcgagagag
    21541 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    21601 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    21661 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    21721 gaatcaactc accacgaacg agcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    21781 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    21841 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    21901 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    21961 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctacccttt ttgcctctcc
    22021 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    22081 atcttaatac ggagttgttt ttggccctgg ttatcggacc cttgcttttc cgagaggctg
    22141 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    22201 cagtgatttt tatctcgacc ctgagtttgg gtggcttggc ccatcttatt tggttcagcc
    22261 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    22321 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    22381 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    22441 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    22501 gttttttaat tggcttttta acagccatga ccaatcgttt cctccatagc ttcttgctaa
    22561 gtgtgagagc aacggatatt gctagtgagc tccttctgga attgagtttg cccttggtaa
    22621 ccttcttcct ggcagaagaa gtccatgttt cagggattat tgccgtcgta gttgctggaa
    22681 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    22741 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    22801 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    22861 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    22921 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    22981 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    23041 tcttgatacc aagtaatcta gaacaggagt atcctctctt gcttttcctt gttgcaggtg
    23101 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    23161 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    23221 aaaaagagtt ggaagacact agaaataaac ttcccctcta tgcggctatt gacaattatc
    23281 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagactggg
    23341 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    23401 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    23461 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    23521 ttttacgttt tctccttcat gaagttttta ctctcggaaa gaccttccgt agctggaaga
    23581 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    23641 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    23701 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    23761 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    23821 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    23881 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    23941 ccaataccct accgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    24001 aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tatgtgactg acttcgtcag
    24061 tcttatctac aacctcaaaa cagtgttttg agcagcttgc ggctagcttt ctagtttgct
    24121 ctttgatttt cattgagtat aagattataa gtgaaggagt atgatatgac atgaaaaagt
    24181 ggtggaaaga gctgatagac aaacctttat taaaagcttt tttgcattat tatcaagcat
    24241 cagatagtga gttgaccagt gtcgcagtag cctactattg gttgatttcg attttccccc
    24301 tgcttttggt ggtggtcaat atcctcccct attttcagat tcctgtggga gaatttttgg
    24361 gctttatgaa agacgttctg cccccaagcc tctatgaagg tgtggaaaaa atagccagag
    24421 aagttttgac gcaaccttca acaggtttat tgagtttttc tgttttatcg gcgttatgga
    24481 gtttttcaaa atctatgaat ttcttgcaaa aagcttttaa caaggcttat ggcgtcgaaa
    24541 agagtcgtgg acttatttcc catcagatgc tgagtctcct agtcagtttt ggcttgcagc
    24601 tcctctttgc gtttgccttg tttttgatct tatttggtca gatgattttg gctttacttg
    24661 ctcattattg gacaaaagat ggcattatct atcaggcttt acaagggttg gcaggtcctc
    24721 tgatttacgc cctcctcttt gctatcttgg tcatgcttta ttattttctt cccaatctat
    24781 ctaacaggaa aattagctat accctaccag gcagtgcctt tgttctctta gtgattttag
    24841 gtttactaac tctgttctct agttatctca attactatgt ccatcatttg gtggatgtcc
    24901 gaattttagg ttccgttctt cttgttgtta tgatgttttg gtttatcttg attgctaaaa
    24961 ttgttatcct aggcgcggtt atcaatgcca gtatgcagag tttgaaagat ccggtcttta
    25021 aaaaagacta actatttatc tattataaaa gcgcatagta tcaagacttt atagaacctt
    25081 gatactatgc gcttttgtgc tttgacagtt ttttgtatag tttttgtcca agatttctaa
    25141 atcatctgat taaattccta ttttccccta tcattgtccc tgttttttcg aaaatggaag
    25201 gagtataata aatctatcaa taaaatgata ggaggaactt tatgggtcat attttctttt
    25261 ttctaagtgt ctttttggca gggattctat ccttcttttc tccttgtatc ttacctttgt
    25321 taccggtcta tacaggggtg ttactagatg ataaggatgg tgctcaggct tctagcggca
    25381 aattttcaat ctcagttact agtttattac gaactctggc ctttatagca ggaatttcct
    25441 ttatatttat tttgttgggc tatggagctg gttttttagg cgatttgctt tatgcttctt
    25501 ggttccaata tcttactggg gcaattatta tccttcttgg tttgcaccaa atggagattc
    25561 tacactttaa ggggctttat aaggaaaaga ggctacaact gcaaggacag gggcaaaatg
    25621 gtaagggcta tagtcaggca tttttattgg gcttgacctt tagttttgct tggacgcctt
    25681 gcgtggggcc ggttctgggg tctgttttgg ccttggcggc ttcaggtggt tcaggagctt
    25741 ggcagggagc tggtctcatg ttggtgtata cgctgggctt ggcgctacca ttcttgcttc
    25801 tagctctgac ctctagttat gttttgaaac atttccgaaa acttcatccc tatctcggaa
    25861 tcctcaaaaa agtgggaggt tttctcatta ttgtgatggg actcttggtt ctgtttggaa
    25921 atgcttcaat tttaagtcaa ttatttgaat aaaatggaaa ggaatatcaa tatgaaaaaa
    25981 tggcaaacat gtgttcttgg agcgggttcg ctcctttgtt tgacggcttg ttcaggcaag
    26041 tccgtgacta gtgaacacca aacgaaagat gaaatgaaga cggagcagac agctagtaaa
    26101 acaagcgcag ctaaagggaa agaggtggct gattttgaat tgatgggagt agatggcaag
    26161 acctaccgtt tatctgatta caagggcaag aaagtctatc tcaaattctg ggcttcttgg
    26221 tgttccatct gtctggctag tcttccagat acggatgaga ttgctaaaga agctggtgat
    26281 gactatgtgg tcttgacagt agtgtcacca ggacataagg gggagcaatc tgaagcggac
    26341 tttaagaatt ggtataaggg attggattat aaaaatctcc cagtcctagt tgacccatca
    26401 ggcaaacttt tggaaactta tggtgtccgt tcttacccaa cccaagcctt tatagacaaa
    26461 gaaggcaagc tggtcaaaac acatccagga ttcatggaaa aagatgcaat tttgcaaact
    26521 ttgaaggaat tagcctagga ggtgtcttat gaatgataag ttaaaaatct tcttgttgct
    26581 aggagtattt tttctagcca taaccggttt ctatgtttta ttgatacgaa atgcagggca
    26641 gacagatgcc tcgcaaattg aaaaggcggc agttagccaa ggaggaaaaa cagtgaaaaa
    26701 aacagaaatt agtaaagacg cagacttgca cgaaatttat ctagctggag gttgtttctg
    26761 gggagtggag gaatatttct cacgcgttcc cggggtgacg gatgccgttt caggctatgc
    26821 aaatggtaga ggagaaacaa ccaagtacga attgattaac caaacaggtc atgcagaaac
    26881 cgtccatgtc acctatgatg ccaagcaaat ttctctcaag gaaatcctgc ttcactattt
    26941 ccgcattatc aatccaacca gcaaaaataa acaaggaaat gatgtgggga cccagtaccg
    27001 tactggtgtt tattacacag atgacaagga tttggaagtg attaaccaag tctttgatga
    27061 ggtggctaag aaatacgatc aacctctagc agttgaaaag gaaaacttga agaattttgt
    27121 ggtggctgag gattaccatc aagactatct caagaaaaat ccaaatggct actgccatat
    27181 caatgttaat caggcggcct atcctgtcat tgatgccagc aaatatccaa aaccaagtga
    27241 tgaggaattg aaaaagaccc tgtcacctga ggagtatgca gttacccagg aaaatcaaac
    27301 agaacgagct ttctcaaacc gttactggga taaatttgaa tccggtatct atgtggatat
    27361 agcaactggg gaacctctct tttcatcaaa agacaaattt gagtctggtt gtggctggcc
    27421 tagttttacc caacccatca gtccagatgt tgtcacctac aaggaagata agtcctacaa
    27481 tatgacgcgt atggaagtgc ggagccgagt aggagattct caccttgggc atgtctttac
    27541 ggatggtcca caggacaagg gcggcttacg ttactgtatc aatagcctct ctatccgctt
    27601 tattcccaaa gaccaaatgg aagaaaaagg ctacgcttat ttactagatt atgttgatta
    27661 atactcttcg aaaatctctt caaaccacgt cagcgtcgcc ttaccgtatg tagggttact
    27721 gacttcgtca gttttatcta caacctcaaa gctatacttt gagctgactt cgtcagtttt
    27781 atctacaacc tcaaagctat actttgagct gacttcgtca gttttatcta caacctcaaa
    27841 gcggtacttt gagaaacctg tggctatctt cctagtttac tttttgattt ttattgagta
    27901 taagaggtct ttcctaagca gttagaggag aattttgcta tactgatact agtaaatggt
    27961 aaaggagcag agcatgacct acacaatctt aatcgtagaa gatgaatatc tggtaagaca
    28021 aggtttgact aaactggtca atgtagcagc ctacgatatg gaaatcatcg gtcaggctga
    28081 aaatggaagg caggcttggg aattgatcca aaagcaggtt ccagatatca ttttaaccga
    28141 tatcaacatg cctcatctaa atggcatcca gttggccagt ttggtacgag aaacctatcc
    28201 tcaggttcat ttggtctttt taacaggtta cgatgatttt gattatgcct tgtctgctgt
    28261 caaactaggt gtggacgact acctgctcaa acccttttct cgtcaggata ttgaggaaat
    28321 gttggggaaa atcaaacaaa aactagacaa ggaagagaaa gaagagcagt tacaagattt
    28381 attgactaat aggtttgaag gaaacatggc ccagaaaatc cagtctcatc tggctgatag
    28441 ccaatttagt ttaaagtctt tagccagtga cttaggtttt agtccgacct atctgagttc
    28501 tttgattaag aaagagttgg gcttgccttt tcaggattat ctggtgagag aacgtgttaa
    28561 acaagccaag ctcttgcttt taactacaga tctgaagatt tatgagatcg cagagaaggt
    28621 tggttttgaa gatatgaact attttaccca acgttttaag cagattgcag gtgtgacacc
    28681 tcgtcagttt aagaagggag aagaccgatg aagcgttctt ctcttttagt tagaatggtt
    28741 atttccatct ttctggtctt tctcattctc ctagctctgg ttggaacttt ctactatcaa
    28801 tcaagttctt cagccattga ggccaccatt gagggtaaca gccaaacgac catcagccag
    28861 actagccact ttattcagtc ttatatcaaa aaactagaaa ccacttcgac cggtttgacc
    28921 cagcagacgg atgttctggc ctatgctgag aatcccagtc aagacaaggt cgagggaatc
    28981 cgagatttgt ttttgaccat cttgaagtca gataaggact tgaaaactgt tgtgctggtg
    29041 accaaatctg gtcaggtcat ttctacagat gacagtgtgc agatgaaaac ttcctctgat
    29101 atgatggctg aggattggta ccaaaaggcc attcatcagg gagctatgcc tgttttgact
    29161 ccagctcgta aatcagatag tcagtgggtc atttctgtca ctcaagaact tgttgatgca
    29221 aagggagcca atcttggtgt gcttcgtttg gatatttctt atgaaactct ggaagcctat
    29281 ctcaatcaac tccagttggg gcagcagggc tttgccttca ttatcaatga aaaccatgaa
    29341 tttgtctacc atcctcaaca cacagtttat agttcgtcta gcaaaatgga ggctatgaaa
    29401 ccctacatcg atacaggtca gggttatact cctggtcaca aatcctacgt cagtcaagag
    29461 aagattgcag gaactgattg gacggtactt ggcgtgtcat cattggaaaa gttagaccag
    29521 gttcggagtc agctcttgtg gaccttgctt ggggccagtg tcacatctct tcttgtctgt
    29581 ctctgcttag tgtggttcag tcttaaacgc tggattgctc ctttgaagga tttgagagaa
    29641 accatgttgg aaattgcttc tggtgctcaa aatcttcgtg ccaaggaagt tggtgcctat
    29701 gaactgagag aagtaactcg ccaatttaat gccatgttga atcagattga tcagttgatg
    29761 gtagctattc gtagccagga agaaacgacc cgtcagtacc aacttcaagc cctttcgagc
    29821 cagattaatc cacatttcct ctataacact ttggacacca tcatctggat ggctgaattt
    29881 catgatagtc agcgagtggt gcaggtgacc aagtccttgg caacctattt ccgcttggcg
    29941 ctcaatcaag gcaaggactt gatttgtctc tctgacgaaa tcaatcatgt ccgccagtat
    30001 ctctttatcc agaaacaacg ctatggagat aagctggaat acgaaattaa tgaaaatgtt
    30061 gcctttgata atttagtctt acccaagctg gtcctacaac cccttgtaga aaatgctctt
    30121 taccatggca ttaaggaaaa ggaaggtcag ggccatatta aactttctgt ccagaaacag
    30181 gattcgggat tggtcatccg tattgaggat gatggcgttg gcttccaaga tgctggtgat
    30241 agtagtcaaa gtcaactcaa acgtggggga gttggtcttc aaaatgtcga tcaacggctc
    30301 aaacttcatt ttggagccaa ttaccagatg aagattgatt ctagacccca aaaaggaacg
    30361 aaagttgaaa tatatataaa tagaatagaa actagctaac tcccagtcaa ttctgggagt
    30421 tttatgcgta attgggcaaa ctttctaggt tgtctatctt gctaaaaaca agaaaaaacg
    30481 gtatgataga agagtgacaa cagaggtaac agagatgaac gagacacaga ttcaaagaga
    30541 aacacgtcag gtagtggaag atgttttaga aaagaccaat ttgaaacagg gggccctttt
    30601 tgttttaggt ctatcttcta gtgaggtgct aggtggtcag attgggaaag aatccagtca
    30661 agagattggt gagctgatag tggagactat cttgggtatt ctaggtagta gaggtatcca
    30721 tttagcagtt caaggttgtg agcatgtcaa tcgggctctc gttgttgaac gtcaggtggc
    30781 agagcagttt ggtctggaaa ttgtcagtgt ccatcctact cttcatgcag gaggttcggg
    30841 gcagttggca gcctttaagt ttatgcagga tccagttgag gttgaattta tcaaggctca
    30901 tgctggattg gatatcggag acactgcaat tggcatgcat gtcaagcatg ttcaggttcc
    30961 gattcgccct attttgagag agattggtca tgcccatgta acggcactga ctagtcgtcc
    31021 aaaattaatc ggaggtgcgc gtgcgcacta tccgcaagat gctattagga agttttgaga
    31081 atgaataaag gagataaaag tgtttaaaaa agaccgtttt tcaattcgta agattaaggg
    31141 agttgtaggc tctgtatttc ttggaagcct tttgatggct ccttctgtag tggacgcagc
    31201 cacctatcac tatgtaaata aagagattat ttcacaagaa gctaaagatt taattcagac
    31261 aggaaagcct gacaggaatg aagttgtata tggtttggtg tatcaaaaag atcagttgcc
    31321 tcaaacaggg acagaagcat ctgttttgac agcttttggt ttgctgactg ttgggagctt
    31381 gcttttaatc tacaagagaa agaaaattgc tagcgtcttt ctagttggaa ctatgggatt
    31441 ggtagttctt cctagtgcag gggctgtaga cccagttgcg accctagcac tggctagtcg
    31501 agagggtgtt gttgaaatgg agggctatcg ctatgttggt tatctatcag gtgacatcct
    31561 caaaacgctt ggcttggaca ctgttttaga agaaacctca gcaaaacctg gagaggtgac
    31621 tgtagtcgaa gttgagactc ctcaatcaac aacaaatcag gagcaagcta ggacagaaaa
    31681 ccaagtagta gagacagagg aagctccaaa agaagaagca cctaaaacag aagaaagtcc
    31741 aaaggaagaa ccaaaatcgg aggtaaaacc tactgacgac acccttccta aagtagaaga
    31801 ggggaaagaa gattcagcag aaccagctcc agttgaagaa gtaggtggag aagttgagtc
    31861 aaaaccagag gaaaaagtag cagttaagcc agaaagtcaa ccatcagaca aaccagctga
    31921 ggaatcaaaa gttgaacaag caggtgaacc agtcgcgcca agaaaagacg aacaggcacc
    31981 agtcgagcca gaaaatcaac cagaagctcc tgaagaagag aaggctgtag aggaaacacc
    32041 gaaacaagaa gagtcaactc cagataccaa ggctgaagaa actgtagaac caaaagagga
    32101 gactaaaaca gctaagggga cgcaagaaga agattacgtg ggtgaggctc ttgttccaga
    32161 acaattacct gagtataagg tgactgaagg aacactcgtt gaagaatcaa ctacagaact
    32221 tgactataaa actgaaacga ctgaggaccc aaccaagtac acggacgaag aaactgtcct
    32281 acgaaatggt gaaaaaggaa gtcaagttac aaaaacaacc tataaaacaa taggaggggt
    32341 taaaactgac caagttcttt caaccagtac ggaagtcacc aaggagcctg taaatcaaca
    32401 ggtaatccgt ggtacaaaac caattgaagg gacaacggtt gagacaagag aagaaatcat
    32461 tccttttgaa acaaaagaac aagaagatga cactttaaaa cgcggaacaa gacaagtaac
    32521 tcaagaaggt gtaaacgata agaaacaaat tactgaaacc tataaaacaa ttcgcggaga
    32581 aaaaacaagt gacgctccta ctatcacaga aacagtgatt gaaaaacctc aagacaaaat
    32641 tattaagaat ggcacaaaag agttagagaa accaaccttg gaatgggcta aaacagataa
    32701 agatgtcttg aagaagagtg cgacagctag ttatacattg actaaaccag ctggagtaga
    32761 aattaaatcg attaaagtag ctctaaaaga taatactgga acagttgtta aagaagtaac
    32821 ggtagaagaa aataacttac aagctacttt agacaacttg aaatattatc aaggttatac
    32881 actatccaca accatggtct atgatcgagg taacggtgaa gaaactgaaa tattagaaga
    32941 taaagaagtt cagttagacc ttaaaaaagt tgagattaaa gatattaaag aaacaagatt
    33001 gatgaaagtg gatgagaatg gaaatgaaac agatagtagc cttctagaaa ctgttccaga
    33061 aaatctaacg tcatattatc taaaaattac cactaatcat aataaagtaa caaggcttgc
    33121 cattactaat atagaggaag taactgagga ggagacatcc ttatttaaag ttactgcttc
    33181 agctcctgat ttaatccaac gtgattcaaa taatagtttg agtcaaacat acacttatta
    33241 catagagaaa cccaaagcat cgcaaaataa cgtttactat aacttcaaag atttagtaga
    33301 tgctatgcag aaaaatccta acggtgagtt taaattagga tcggatttaa atgcaacaaa
    33361 tgtacctaca ccaagtaaat catatgtaac aggtaaattt acaggtcact taacaagtgt
    33421 tgatggtaag catttctcca ttcataacac tgctcgtcca ttatttgata gagttgaagg
    33481 gggttctatc aaaaatatta atttaattaa cgttaatatt aatatgcctt gggcaaatca
    33541 attagcttca ttagctcaaa cagtgaaaaa tgcaactgtt gaaaatatta aagtaacggg
    33601 tactatcgtt ggtaataaca atgttgcggg tattttggat aaattagatg atgcaggtat
    33661 tatgactaat gttgctttta tcggaaaagt tcaatctgtt ggtgataaag ggtggaactt
    33721 ggctgggatt gcatctgaga tttatcgagg caatttaaat aaagcttatg cagatgttga
    33781 acttaaaggt ttaaatactc gtgcaggtgc tatagtagga catttagctc atgattttaa
    33841 tccaagagat gttggtgctt ggtctaatgt aagaaattct gtagccaaag gtactattga
    33901 tgttgctaga ggtgatgtag gcggtttaat tggtaaagac tggccttggg gaaccattga
    33961 taacaatatc agcttagtga atgttaagcg tggtgatatt ttctttggtt ctaatgatat
    34021 ggatgatgaa tttgtaagca attggattaa acctaataat gcaacagtta tcggtgtgag
    34081 ttctggagat aaaacccata aacaatcgtc taaaattaaa gaaatttcac aggtagaagc
    34141 tgataagaaa attaaggata tgggtatcac tgctgataca tttgaagtaa ctgagcattt
    34201 ggttgataag ttgaatcgcc gtatattacg tgatgaagaa tacaaaacaa ttcaagatta
    34261 taatgcaaat cgtgagcttg tttatcgtaa tgttgaaaaa ctccaaccgt tctacaacaa
    34321 agaatggatt gtgaatcaag ggaacaaact tacaactgat agtccattaa tgaataaaga
    34381 agtattgtct gtgactgcaa tgaaaggtaa tgactttatt acagacctta cagatgctga
    34441 ccatattatg gttcattacg cagataagac aaaagatatc tttacgattt ctcctaaaga
    34501 ctctcaagtt aagcaagtaa aagaatacag tgtcgcagag cttggtgaag tcgtctatac
    34561 accaaatatg gttgttaaag atcgtgcaga tttaattagt gctattgaag gtattttaag
    34621 tccaattgaa ttacaatctg atccaattta tcaacgatta ggaagaactg gggataacag
    34681 agttaatgca attaagaatc tttacttaga agaaagcttt aaagaagtaa aagatcatct
    34741 taatacattt gtgacaaaat tagttgaaaa tgaagatcat caactgaata cagatgaagc
    34801 tgcaaaacgt gccttgatta agaaaattga agataacaaa gctgctgtcc tgttaggatt
    34861 aacataccta aatcgttatt acggtgtgaa atttgataac ttcaatatta aagaattaat
    34921 gctattcaaa ccagattttt atggtaagaa tgtaagtgtt ttagatcgat taatagaaat
    34981 tggttcaaaa gaggactata ttaagggaag tcgtacacag gagtccttcc gtgaagtggt
    35041 ggcgaaaaat actctttctg gaaacttaca tgacttcttg acctacaata tgaaactatt
    35101 cacaaatgaa acagacataa atgtttggtt taagaaagct attgaaaata atgcttatgt
    35161 agttgaacaa ccgtcaacta accctgcatt tgctaataaa aaatatcgtc tatatgaagg
    35221 acttaataac ggacaacatg gacgcatgat tttatcgctt ctgaacttga aagatgcaca
    35281 tttatttatg atttcaacat ataatactat ctcatttagt tcgtttgaaa agtatggtaa
    35341 agatacagaa gaaaaacgtg aaacgttcaa gagtgaaatc aataaacgtg ctaaagagca
    35401 agttaattac ttagattttt ggtcacgcct tgccactgat aatgtccgcg ataaacttct
    35461 taagagtcaa aatgtagttc caactcctgt atgggataat catggtgcac ccggtggttg
    35521 gcctgataga tttggtcatc gaaaagataa accggattat gcacctattc gtgaattctt
    35581 tggacgtatt gataagtatc atgattataa gtatgggtat ggagcgtatg cttacatctt
    35641 tgctgatcca cagcctatgg atgctgtata ttttgttatg tcggatttaa taagtgaata
    35701 tggcacatct gcctttacac atgagactac ccacgtaaat gaccgaatgg catatctggg
    35761 aggtcataga catcgacagg gtacagatct tgaagcattt gctcaaggta tgttacaaac
    35821 tccagcagaa catggacatc aaggtgaata tggcgcactt ggattaaata tggcatttga
    35881 acgttcaaat gatggaaacc aatggtataa tccagatcct accaaacttc aaacacgtga
    35941 ccaaatcgac cattacatga agaactacaa tgaagctatg atgatgctcg attatgcaga
    36001 agctgaggct gttcttccta aggttaaagg tgacaatagt aagtggttca agaaaattga
    36061 tcgcgaaaca cgtcgaccaa tggacagaaa taaactaagt ggtcctcacc aatgggacaa
    36121 agtgcgtgat ttgatagacg ctgagaaaac aactaacctt gaaaccatcg atgacttggt
    36181 aaataataat ttcatgacca ttcacggaaa tccaggtaat aaggtcttcc acccagagga
    36241 ctttggtacg gcatatgtca atgttaatat gatggctggt atttatggcg gtaatacgag
    36301 tcaaggtgcc cctggttctc tatccttcaa acataacgcc ttccgtatgt ggggttacta
    36361 tggatatgaa catgggttca ttgactatgt ttcaagcaaa catcaaggtg cagccaataa
    36421 agaaaataac ggtctattag gtgatgattt cattattaag aaagtttcta ataaccaatt
    36481 ttcaaacctt gaagattgga agaagcaatg gtatggggaa gttcttacaa aatctaaaaa
    36541 aggttttgca ccaattgaaa ttaatggcac tcaaatttca acctatgaac agttgaagac
    36601 tatgtttgat gaggctgtta ctaaagattt aacggaacta aacgatagta gtattaaaga
    36661 caaataccga aatacagttg tcttgaaatc gaaagtcttt aaagctctcc ttaaaaacac
    36721 agacggtttc tctggtgatc tatttactgc accacaagca tagaatgaat aaaatcgtaa
    36781 aaaggtagat cagctttgtc tgtatctgcc tttttatgct atacttaagg tatgcataga
    36841 aaaacagtga ttgattttag gactttgggg gagagatata cctttaccaa gcctattaaa
    36901 gagttgaaaa cgagaaatgt agaagaagtg gcagatttgc tggcacaagt ggaaagctac
    36961 caagagcaag gttattatgt ggtggggtat gtcagctacg aggctgcacc tgcttttgag
    37021 gaaaaattag cagttcacaa ggatccccta ctgggagagt acctgcttta ttttactgtt
    37081 catgatagcg tagaaacttc ccctattcct ctgacttatg aggatattga tttgccctca
    37141 aattggcagg aagtaacgtc tgcagcagac tatgaaaagg ccattgccca aattcaccat
    37201 catttacggc agggagatac ctatcaggtc aactacaccg tccaacttaa gcaaaagtta
    37261 aatgccaatc cttttgccat ctacaatcgt atggtggtag agcaggaggc gggctacaat
    37321 gcctatgtgg aacatgacga gatggcagtg atttccatga gcccagagct cttttttgag
    37381 caaaatgatc gcgagttgac aacacgacca atgaagggga cgactcagcg tggggtaact
    37441 gaccaagaag atcttgaaca ggccagttgg ttggaacagg atcccaaaaa tcgctctgaa
    37501 aatatgatga ttgtggacct cttgcgcaat gatatgaacc gtatttctga agttgggagc
    37561 gagcacgtgg agcgtctgtg tcaggtagag cagtattcaa ctgtttggca gatgacttcg
    37621 accatcaaga gtcagttgcg agaggatgtg gaccttgttg aaatcttccg ctcactcttt
    37681 ccttgtggtt ccataacggg tgcaccgaaa attgcgacaa tggagattat caaggacttg
    37741 gagcctcaac cgcgtggagt ctactgtgga acgattggtc tcttgcttcc aaatggacga
    37801 cggattttta atgtggccat tcgtaccatt caacttcaca aaggtcaagc catttatgga
    37861 gttggcggag ggattacttg ggatagcaca tgggaatctg aataccgaga ggttcatcaa
    37921 aaggcagcag ttctttatcg taaacaagct cgcttccaac tgattacgac aggggaaatc
    37981 agccagaaga acctgttgtt tgaagatcaa catctggaaa gactgagaaa agctagtcgt
    38041 tattttgcct ttccttttga tgcagaagac ttgggacaca agattgagga agagtgtcag
    38101 gattgtgaag ctaatcgaga ttaccgcttg cgaatcagcc ttagcaaatc tggagagata
    38161 gaagtcaatc gtcaagtatt aacccctctc agtacaagct tttgtcaggc ccaagtctgc
    38221 cttcaggaag ctgctttgaa tcaatccttt acctacttta aaaccactca ccgaccgcat
    38281 ttgagcctag gagaacaaga gaagatttac cacaataagt caggagaact gcttgaaacc
    38341 tctataggaa atttggttct gaaaatcgct ggaaaactct acacaccgcc tatccgactt
    38401 ggaatcttgc caggaattta ccgtcagtat ttgctagaaa caggacaggt agaagagaaa
    38461 gtcttgacct tggcagattt agcccaagca gaagctattt acggctgtaa tgcagtgaga
    38521 ggcttgtatg aactaagcct tgaggagaac tagatgaaac tgatattttt gcatgggtta
    38581 gggcagtcag cagagtcttg gaaagaagtt cggaatctac tgacagatta tccttctgag
    38641 gctatcgagt tatttccttc tggagttagt aactatcaac aagctaagga gcgagtttat
    38701 cagcacctag ctcaagagac agaacctttt gttttgattg gattgtcctt aggtgctgcc
    38761 ctggcactag aactttccag ttacgattta ccaaatcttc gagctttgat tctgtcagga
    38821 tgcccgctta aattagcagg gaatatccta ttttatcttc agttgctgat ttttaaacta
    38881 cttcccaaaa gagtatttga aaaacaggga gcagacaagg ctcttatggt cggagtttct
    38941 gaggagttga agacacttga tttaacggat atagcaggaa cttgccctta tccaacctta
    39001 ctaatttgtg gtatcaaaga taaaccgaat cttagttcta tgagaagtct tcataaacta
    39061 atatcagaat cccaatttca gattatccca gatggccctc atgtcttgaa taaggcaaaa
    39121 ccaaaggagt ttgtagaaaa gaccagaagt ttccttgaat tgctgaaata agtttgataa
    39181 aataatattg aaatcgatgt cataattatg ggagaaagaa atgaataaac gtctattttt
    39241 aaaaatgagt ctggtgacgt tgccaatttt agccttgttt tcacaacctg tgttagcaga
    39301 ggaaaacatt catttttcga gttgtaagga agcttgggct aatggctatt cggatcttca
    39361 tgagggagaa cctggttatt ctgccaagtt ggaccgcgat catgatggcg tggcttgcga
    39421 attgaaaaat gctcctaagg gtgcttttaa agcaaaacag tcaacggcta ttcaaatcaa
    39481 cacaagttca gcaacaacaa gtggttgggt taagcaggac ggcgcttggt actactttga
    39541 tggaaatgga aatctagtga aaaatgcatg gcagggaagc tattacctga aagctgatgg
    39601 taaaatggca cagagtgaat ggatttatga ctcttcttat caagcttggt attatttgaa
    39661 atcagatggt tcttatgcaa aaaatgcatg gcaaggagct tattacctta aatcaaacgg
    39721 taaaatggca caaggtgagt gggtttatga ttcttcttac caagcatggt attacttgaa
    39781 atcagatggt tcatatgctc gcaatgcatg gcaaggaaac tactatttga aatcagatgg
    39841 taaaatggct aaaggtgaat gggtttatga tgccacctat caagcttggt attatttgac
    39901 atcagatggt tcttatgctt acagtacatg gcaaggaaat tactatctaa aatcggatgg
    39961 taaaatggct gtcaatgaat gggttgatgg tggacgttat tatgttggcg ctgacggagt
    40021 ttggaaggaa ggtcaagcaa gtacagcttc ttctagtaat gatagcaata gtgaatattc
    40081 tgctgcttta ggaaaggcaa aaagttataa ttcgttattc cacatgtcaa aaaaacgtat
    40141 gtatagacaa ttaacttctg attttgataa attttcaaat gatgcagctc aatatgccat
    40201 tgatcattta gatgattaac agatactggt aggcgaaaaa attccttata attcatttac
    40261 gcaaaccttt gcataagtga atggattttg atatactagt actgtaagca ttttcaatta
    40321 ctacacaatg aaaaaggaga atatgatgag tcaaaagatt attgggattg accttggtgg
    40381 aacttctatc aaatttgcaa tcttaacaac agcaggagaa atccaaggaa aatggtcaat
    40441 caagaccaac attttggatg agggaagtca tatcgttgat gatatgattg agtctattca
    40501 acatcgtttg gacttgcttg gattggcagc agcagacttc caaggtattg gaatgggatc
    40561 accaggtgtt gttgaccgtg aaaaagggac tgttatcggt gcctacaact tgaactggaa
    40621 aacccttcaa ccaatcaaac aaaagattga aaaagctttg ggcattccat ttttcatcga
    40681 taatgatgcc aacgtagcag ctcttggtga gcgctggatg ggtgctggtg ataaccaacc
    40741 agatgttgtc tttatgacac tcggtactgg tgttggtggt ggtattgtcg cagaaggcaa
    40801 attgcttcat ggtgttgctg gtgcagcagg tgaacttggt catatcactg ttgattttga
    40861 ccaaccaatt gcatgtactt gtggtaaaaa aggctgcctt gagacagttg cttcagcaac
    40921 aggaattgtc aacttgactc gtcgctatgc cgatgaatac gaaggcgatg cagccttgaa
    40981 acgcttgatt gataacggag aagaagtaac tgctaagact gtctttgatc tcgcaaaaga
    41041 aggagacgac cttgctttga ttgtttaccg taacttctca cgttacttgg gaatcgcttg
    41101 tgctaacatt ggttcaatcc taaacccatc aacaatcgtc atcggtggtg gtgtgtcagc
    41161 tgcgggagaa ttccttctac aaggtgttca aaaagtttac gatgaaaata gtttcccaca
    41221 agtacgcaca tctactaaat tagctcttgc aactctagga aatgacgctg gagttatcgg
    41281 agcagcatca cttgtattgc aataagataa tgagagagga aaatgctaac ctagagttag
    41341 taatgttcct cttttatttt ttatgctata ctagttagga caatgaatga ggtgagagta
    41401 aatgacaaaa gcagatacga tttttaaaga gaatattgaa cgcattctaa aggaaggtgt
    41461 tttctcagag caggctcgtc ctaagtacaa ggatgggact gttgctaatt ccaagtatgt
    41521 aactggtgcc ttttccgagt acgacttatc taaaggagaa tttcctatca caaccttgcg
    41581 tcccattgca atcaaatccg ccatcaaaga agttctctgg atttaccaag accagtcaaa
    41641 tagcttagaa gtgcttaatg acaagtacaa tgttcactac tggaatgact gggaagttgg
    41701 agacacggga accattggtg agcgctatgg tgccgttgtt aagaaacacg acattatcaa
    41761 taagcttctc aaacagttgg aaaccaatcc ttggaaccgc cgcaatatta tttctctctg
    41821 ggattaccaa gctttcgaag aaacagatgg gctgctcccg tgcgcctttc agaccatgtt
    41881 tgatgttcgg cgtgttgatg gggaaatcta tctggatgcg accttgaccc agcgctccaa
    41941 tgatatgctg gtggcccacc acatcaacgc tatgcagtat gtggctttgc agatgatgat
    42001 tgccaaacat tttggctgga aggttgggaa gttcttctac ttcatcaaca acctccatat
    42061 ctatgataat caatttgaac aagctcagga attgctccgt cgggagccgt caaactgcca
    42121 accacgcttg gttttaaatg ttcctgatgg gactaatttc tttgatatca aagcagaaga
    42181 ttttgagttg gtggattatg accctgttaa gccacagttg aagtttgacc tagctattta
    42241 aaagaataga aaaaagaagt tgagaataat cccaacttct tttgtttctt aacgtgatac
    42301 gcggcgacga gctgcttttt tacggttttc ttcgatgaaa gctgcttttt gctcttctgg
    42361 ttcgattact ttctttttaa atgcgtatac tgcacctgca acggcagcga cagttcctgc
    42421 gacacctgtt acaagacctt tagcgaatcc tttagccatg agtcttcctc ctttatattc
    42481 tcaatcagcc agcctcctca agaggtcaca tttttctgac tgaccttttt gtgttataat
    42541 aatagtaacg aaaaaatggg aatttttcaa ggaaaaaaga tgaaaacaaa aataattgtg
    42601 attgttggac cgactgctgt tggaaagacg gctctagcta ttgaagttgc aaagcgtttt
    42661 aatggcgaag tggttagtgg agatagccaa caagtctatc gaggacttga tattgggacg
    42721 gccaaggcta gtccagaaga gcaggcagct gtttctcatc atttaatcga tgttagagag
    42781 ataaccgagt cttactcggc ttttgatttt gtttcagaag ctaagatgac tattgaggat
    42841 attcacagcc gtggcaagct agccattatc gccggtggga ctggacttta tatccagagc
    42901 ttgctagaag gttaccacct aggtggggag actcctcatg aggagatttt agcttatcga
    42961 gctagtttgg agccatattc agatgaggaa ttagcccatt tggtggatca agcaggcctt
    43021 gagattcccc agtttaatcg tcgtcgtgct atgcgtgcct tagaaattgc ccattttggt
    43081 caggatttgg aaaatcaaga gattttgtat gaaccgctga ttatctgctt ggatgatgaa
    43141 cgtagtcaac tttatgagcg tatcaaccac cgagtggatt tgatgtttga ggctgggctt
    43201 ttggatgagg ccaagtggct gtttgaccat tcccctaatg tacaggctgc taaaggaatt
    43261 ggctataagg aactctttcc ttatttccgt ggagagcaga ccttggagga agctagtgag
    43321 agtctcaaac aggcgacccg tcgttttgcc aagcgtcagc tgacctggtt ccgtaatcgc
    43381 atgcaggtca ccttttatca gattggagaa tctggtgtac aagaccgcat tttaagccag
    43441 atagaggagt ttttagatga ttgaaacgga gaaaaaagag gagcgagtcc tgctgattgg
    43501 tgtggaattg cagggtatgg acagttttga cctctccatg aaagaattgg ctagtttagc
    43561 gaaaacggca ggggcagtcg ttgtagatag ctacagacaa aaacgtgaaa aatatgattc
    43621 caagaccttc gtcggctctg gtaagttgga agagattgcg tttatggtgg atgcagaaga
    43681 aatcactact gtcatcgtca acaaccgtct gaccccaagg cagaatgtca atctagagga
    43741 agttctcggt gttaaggtca ttgaccgtat gcagttgatt ttggatatct ttgccatgcg
    43801 ggctcgaagc catgaaggga agctccaagt ccacctagcc caactcaaat acctcttgcc
    43861 tcgcttggtt ggtcagggga ttatgctcag ccgtcaggca gggggaattg gttcccgtgg
    43921 tcctggtgaa agccaactgg agctgaaccg tcgtagcgtt cgcaatcaaa tcacggatat
    43981 cgagcgccag ctcaaggtgg ttgagaaaaa tcgtgcgact gtcagagaaa aacgtttgga
    44041 gtctatcact tttaagattg gtttgattgg ttataccaat gctgggaaat caactatcat
    44101 gaacatcttg accagtaaga cccagtatga agcagatgag ctctttgcga ctctggatgc
    44161 gacaaccaag agtattcatc tgggaggcaa cctccaagta actttgacag ataccgttgg
    44221 ctttatccaa gatttgccga cagagttggt gtccagtttc aagtcaacct tggaagaaag
    44281 caagcatgtg gaccttctgg ttcatgttat cgatgctagc aatccttacc acgaggaaca
    44341 tgaaaaaacg gttctctcca tcatgaaaga cctggacatg gaagatattc ctcacttgac
    44401 gctttataat aaagcggatt tggtggagga tttcacgcct acccaaacgc catataccct
    44461 catttctgcc aagtctgagg acagtcgtga aaacttgcaa gcattattgc tagataagat
    44521 taaggaaatt tttgaagcat ttaccctgcg agtgcctttt tcaaagtcct ataagattca
    44581 tgatttagag agtgttgcaa ttctggaaga acgtgattat caggaagacg gcgaagtgat
    44641 tacaggctac atttccgaga aaaataaatg gaggttagaa gaattttatg actgatatta
    44701 aaactttggc tctaaagtat ggaggttata caagtctgga caaggtctat ctggatcagc
    44761 ttctagctgg taagacagag caggagcagt taacacttat tacacctccg ccaagtgttg
    44821 ttaatgccta ctttgcagaa ctctatcaga aaaaaagtcc tcaggctgcg acggattatt
    44881 ttgcagaact cagtcaggaa ctgaatcttt acaatactga gccaagtttc accctagaaa
    44941 ataagtcttt tattcggctt aatctgtctg gtaaatcctt tggtttttgt tatgagagtg
    45001 acggctttgg tcggattttc tctgaaaatg aggagaaaat atcggatgac ttgctctttg
    45061 aaattgcgca aattttcccc catcaactag tctttgaaga gtctggtaag atttacatga
    45121 agcctgtcga ggacgaggaa gttgtcagcc tagaaagtct cacagctttg actgatttgg
    45181 aaagattggc tgatggtcga aaacgtctca aaggctacag ccaagaggat ttattgcaag
    45241 aagctgctgc tttttctggc aaacgctatt tccgatcgga aaaccgcaca gccatgttat
    45301 atattgatta attagaaagt atcgaatgga tattcaattt ttaggaacgg gggctggtca
    45361 gccctctaaa gctcgcaacg tttcaagtct cgccctgaaa cttttggacg agattaacga
    45421 agtttggctc tttgactgtg gagaaggtac gcaaaatcgc attctggaaa ccacaattcg
    45481 accacgtaag gtcagcaaaa tctttattac ccatctgcat ggagaccaca tttttggttt
    45541 gccaggtttc ctttctagcc gtgcctttca ggccaatgaa gagcagacag atttggaaat
    45601 ctacggacct caaggaatca agtcatttgt cttaaccagc cttcgtgtgt caggttctcg
    45661 tctgccctac cgcattcatt tccatgagtt tgaccaagat tctctgggta aaattcttga
    45721 aaccgataaa ttcactgtgt atgcagagga gctggaccac actattttct gtgttggcta
    45781 tcgtgtcatg caaaaggatc tagaagggac gctggatgct gaaaaactca aggctgctgg
    45841 tgttccgttc ggcccgcttt ttggtaaaat caaaaacggc cagaatcttg ttttggaaga
    45901 cggaactgaa atcaaggcag cagactatat ctcagcgcca cgtccaggta agattatcac
    45961 tattttagga gacactcgaa aaacggatgc cagtgtgcgt ctggctgtca atgcagatgt
    46021 cctagttcat gagtccactt atggcaaggg tgatgaaaaa attgctcgta accatggtca
    46081 ctcaactaat atgcaagctg cacaagtagc ggtagaagca ggtgccaaac gcctcctact
    46141 caaccatatc agtgcccgtt tcctctcaaa agatataagc aaactcaaga aggacgctgc
    46201 cacaattttt gaaaatgtcc atgtggtcaa agacttggaa gaagtggaaa tctagcagtc
    46261 acagaaagga taagtatgcc tactattctc attaccggag ctagcggtgg tctagctcaa
    46321 gaaatggtca aactcctgcc caatgaccaa ctcatcttgc ttggtagaaa taaggaaaaa
    46381 ttagcccaac tctacggaaa ttattcccat gcagaattga ttgaaattga tattaccgac
    46441 gattcagccc tagaagctct ggtaactgat ctttatctcc gctatggcaa gattgatgtc
    46501 ttgattaaca acgctggtta cgggattttt gagggatttg accagattgc tgataaagat
    46561 attcaccaga tgtttgaggt caataccttt gccctgatga atctgtctcg tcaccttgcg
    46621 gctcgtatga aggaaagcag caaagggcat atcatcaaca tcgtcagcat ggcaggtcta
    46681 atagctactg gcaagtctag tctttactca gcgaccaagt ttgcggctat tggtttttca
    46741 aatgctctgc gactcgaact tatgccctat ggagtctatg tgacaacagt caatccaggt
    46801 ccaatccgaa caggattttt tgaccaagct gacccagatg gaacttatct taaatcggtt
    46861 gaccgcttcc tcttagaggc agatgcagtg gctaaaaaga ttgtcaagat tataggcaaa
    46921 aataaacgag aactcaatct cccgattttg ttgaacctag cccataagtt ttatactctc
    46981 tttcccaagc tagctgataa gttggcaggg gaaactttta attataagta aaaagaacca
    47041 atgtgcaggt tgttgctagc ctacatattg gttcttatca tttctcaact atcaaactga
    47101 acttcttcta gtagatagtc gataaagcgt tcgcccatct tagataggct ggttttctca
    47161 tgctggatat agaccagctc aatcgggtca tcaatatcca gtgggataga aacgatattg
    47221 tctccgttta ggttgctgtt caaaatccct gtcgcaatgg tataaccatc caaaccaatc
    47281 aagagattaa agagggtggc acggtcactg accacaatgg atttcttgtg gtgttcttga
    47341 gaaagaatct cttctgaaaa gtagaaggag ttgtgcgtcc cttggtcata gctgaggtaa
    47401 gggaaattct ccaaatcaga cagtttcacc ttgtctttct ttgccagagg gttggtcttg
    47461 ctgacaaaga tatgcggttg cgctgtgaag agatggtggg ctagcaggtg attgtcatcc
    47521 agcatcttgg ttaaaacatc acggttgtaa ctgtttaaga agaggacccc gacctcactg
    47581 cggaagttct tgacgtcgtc gataatctcc caagtccgag tttcacgaag gaagagttcg
    47641 tatttctcca tatcgctttt cttgagcaaa gagacaaagg cattgaccac aaaggcatag
    47701 tgttgagacg aaacgctaaa gagttcgcgg tgggcgacag gatttttata gcgttcctcc
    47761 agaagctggg tctgctcgac aacctgacgg gcataagaga gaaactccat cccatcacgg
    47821 gtcaaggtga ttcccttggg attgcggata aagatctcaa tgcccatttc attttccaaa
    47881 tctctcacag cattggaaag acttggctga gtgataaaga gttgcttggc tgcctcattc
    47941 atggagccag tttcgacgat tttgataata taatgtaatt gttgaattct catgttttta
    48001 ttgtaccaca cttgccttag aatcgctaaa gaagatagga aaataaggag cattgtgtga
    48061 gtctcttctt gaaaaaaaca caaaattttg ctagaatgag tcttatgaaa acattctatg
    48121 atgtgcaaca attcctcaaa cgatttggta ttattgttta catgggaaaa cgcttatatg
    48181 atattgaact gatgaagttg gaactatctc ggatttacga tgcagggttg atggataaat
    48241 tagactatct agaggcagaa gcagttcttc gcagagagca caaggtagaa ttggattata
    48301 ttgagaaaaa tggagaaaag aactaatggt tacttggatt ttgtgggcac ttatactagc
    48361 aatgttggcg tggatgggct ttaactatct tcgtattcgc cgtgcggcta aaattgtgga
    48421 caatgaggag tttgaagcct tgattcgtac gggtcaattg attgatttgc gcgacccagc
    48481 agaattccac agaaaacata tccttcgtgc acgcaatatt ccttcaagtc agttgaaaac
    48541 tagtcttgca gcccttcgta aagataaacc tgtccttctc tacgagaacc aacgtgcgca
    48601 acgagttaca aatgcagctc tttacttgaa aaaacaaggt ttttctgaga tttatatcct
    48661 ttcttatggc ttggattctt ggaaagggaa agtgaagact agctaacctt atttccaaat
    48721 tagtcgaatg ataggatgaa gctattgttt tatagtataa ttaatttgta taaaatttaa
    48781 agagttctta gaacatgaaa gaaaagaaga aaaatccact ttttgtgggt atcttgtcga
    48841 ttattcttgg tttgttattt ccaattgtag gcctgatttt gggtatcata ggattggtct
    48901 tggctatttc ataccaaaaa gagtcacaat tagactataa aatagaaaag attcttaata
    48961 tcttaggaat tgtgatttct gtagttaact ggattgtagc aatcgcctta atttttcgat
    49021 aaataaaaga aaaaagcttt agttttaaag ctttttttgt tttatcgact catctctaaa
    49081 tagtttttaa tgatttgtaa ctctttttgg ttcaaagggc ggtagttacc ttctgctaaa
    49141 tctgggttca atgtgaagtc cccaaattgg attctcttga ggctagtcac cttaacacca
    49201 accgagagga acattttctt gatttgatga aattttcctt ctgaaatggt gatagaggct
    49261 tgactgatgg agggacttgc agatagaatc tctagttttg cgggtttaca gacagtacca
    49321 tctaaaaaga caattccctt ttgaaaggct tggatatggt caggtgttag aagtccatta
    49381 acctcaactt gataagtctt atcgacatga tattggggat ggaggagttg gaagcccaag
    49441 ggaccgttat cggtcaagag aaggagtcct gttgtatctc ggtccagtcg gccgacggca
    49501 tagagcttgt cagactggat gtcagatgga agcaagtcca tgacggtcgg aagttccttg
    49561 tctttgttgg ctgtaacgac accagcaggt ttatgaagca taagataggt gtgttcatag
    49621 ccttgaatga ttcgatcctg aaaaaggagt tcttgtagtc ctgtatcgat attttgagct
    49681 agggagcggg ctgggcaacc atcgactaga atgtcccctt tgagtaaggc ttgtttcatg
    49741 gcctttcggc tgattttttc ttgagctaat aaattatcta aacgcatact gtgcctatct
    49801 tatcataagt cgcttgcttt gaaaaggctt gacgtgaaaa gaaaagcgga gtgaaaacat
    49861 ttacacttgc ttgagttatg ttatttattt gaaattatgg tataatcgtt cagttagaaa
    49921 ataaattttg aatattatag aggaaatcat gacaaaatta agagaagata tccgtaacat
    49981 tgcgattatc gcccacgttg accacggtaa aacaaccctg gttgacgaat tattgaaaca
    50041 atcagaaacg cttgatgcac gtactgaatt ggcagagcgt gctatggact caaacgatat
    50101 cgaaaaagag cgtggaatca ccatccttgc taaaaatact gccgttgctt acaacggaac
    50161 tcgtatcaac attatggaca caccaggaca cgcggacttc ggtggagaag ttgagcgtat
    50221 catgaaaatg gttgacggtg ttgtcttggt cgtagatgcc tatgaaggaa ccatgccaca
    50281 aactcgtttc gtattgaaaa aagccttgga acaagacctt gtcccaatcg tggttgttaa
    50341 caaaatcgat aagccatcag ctcgtccagc agaagtagtg gatgaagtct tggaactttt
    50401 catcgagctt ggtgcagatg acgatcagct tgatttccca gtggtttatg cttcagcgat
    50461 caacggaact tcttcattgt cagatgatcc agctgaccaa gaaacgacta tggcaccaat
    50521 ctttgacacg attatcgacc atatcccagc tccagtagat aactcagatg agcctttgca
    50581 gttccaagtg tcacttttgg actacaatga cttcgttgga cgtatcggta tcggtcgtgt
    50641 cttccgtggt acagttaagg ttggggacca agttaccctt tctaaacttg acggtacaac
    50701 taaaaacttc cgtgttacaa aactcttcgg tttctttggt ttggaacgtc gtgaaatcca
    50761 agaagccaaa gcgggtgact tgattgccgt ttcaggtatg gaagacatct ttgtcggtga
    50821 aaccatcact ccgacagatg cagtagaagc tcttccaatc ctacacatcg atgagccaac
    50881 tcttcaaatg actttcttgg tcaacaactc accatttgct ggtaaagaag gtaaatgggt
    50941 aacttctcgt aaggtggaag aacgcttgca ggcagaattg caaacagacg tttcccttcg
    51001 tgttgaccca actgattcac cagataaatg gactgtttca ggacgtggag aattgcactt
    51061 gtcaatcctt atcgaaacaa tgcgtcgtga gggctatgaa cttcaagtat ctcgtccaga
    51121 agttatcgta aaagaaatcg acggtgttaa atgtgaacca tttgaacgtg tacaaatcga
    51181 cactccagaa gaataccaag ggtctgttat ccaaagcctt tctgaacgta aaggtgaaat
    51241 gttggatatg atttcaactg gtaatggtca aactcgtttg gtcttccttg ttccagcgcg
    51301 tggtttgatt ggatactcaa ctgagttctt atcaatgact cgtggttacg gtatcatgaa
    51361 ccataccttc gaccaatact tgccattgat tccaggggaa attggtggac gtcaccgtgg
    51421 tgcccttgtt tctatcgatg ctggtaaggc tacaacttac tcaatcatgt ctatcgaaga
    51481 acgtggtacg atctttgtca acccaggtac tgaggtttat gaaggaatga tcatcggtga
    51541 aaactctcgt gaaaatgact tgacagttaa catcacgaag gcaaaacaaa tgaccaacgt
    51601 tcgttcagct actaaggacc aaacagctgt tatcaagacg cctcgtatct tgacacttga
    51661 agagtctctt gagttcttga acgacgatga gtacatggaa gtaacgcctg agtctatccg
    51721 tttgcgtaaa caaatcctta acaaagcaga gcgtgagaaa gctaacaaga agaaaaaatc
    51781 agctgaataa gagctagaaa gagagaaaga tggtctattt agtcctagga attttactgc
    51841 tcctactcta tgtatttgcg acaccagaaa gcattaaagg gacagtcaat atcgtcgcta
    51901 tggtatgtat tttagtggca ctcttgattt tattggttct atcttttctg aaaatttttc
    51961 aattaccaac agaaatattc ctagcaatag ccatgttgat cctagcttac tttagtgtta
    52021 gagacatcac actcatgcca gtcaaaaaaa gtaaaagaag ataaaaaaga gagtttcggc
    52081 tctctttttg ctaggaattt tataatagtt tgaattgctt tttagttaac accatctctt
    52141 ttgcttgtat agtatgaatg ggaaaaactt gaataaaatt cgttaatggc atctatttta
    52201 tatttggtta gtactggttg catattattt tga
//
LOCUS       DAVMCG010000010        48236 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVMCG010000010 DAVMCG010000000
VERSION     DAVMCG010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48236
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.010"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(150..860)
                     /gene="treR"
                     /locus_tag="VYP66_000728"
     CDS             complement(150..860)
                     /gene="treR"
                     /locus_tag="VYP66_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1850318.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            1045..3012
                     /gene="treP"
                     /locus_tag="VYP66_000729"
     CDS             1045..3012
                     /gene="treP"
                     /locus_tag="VYP66_000729"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1850319.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKIEGDTNLQAEFVAQEEAEFVSHEPVELTSVEII
                     SPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVIVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATITGTYPTTIQAGASLMVATRI"
     gene            3190..4815
                     /gene="treC"
                     /locus_tag="VYP66_000730"
     CDS             3190..4815
                     /gene="treC"
                     /locus_tag="VYP66_000730"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1850320.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDTSENAGFSTGTPWLKVGKSYKDINVENEIKGLIFTFY
                     QDLIRLRKEMPIISEGNYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            5071..5319
                     /locus_tag="VYP66_000731"
     CDS             5071..5319
                     /locus_tag="VYP66_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1850321.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            5526..6320
                     /gene="racE"
                     /locus_tag="VYP66_000732"
     CDS             5526..6320
                     /gene="racE"
                     /locus_tag="VYP66_000732"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1850322.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            6317..7288
                     /locus_tag="VYP66_000733"
     CDS             6317..7288
                     /locus_tag="VYP66_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1850323.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKLSL"
     gene            7264..7785
                     /locus_tag="VYP66_000734"
     CDS             7264..7785
                     /locus_tag="VYP66_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1850324.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPY
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            7782..8243
                     /locus_tag="VYP66_000735"
     CDS             7782..8243
                     /locus_tag="VYP66_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1850325.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            8234..8974
                     /gene="xerD"
                     /locus_tag="VYP66_000736"
     CDS             8234..8974
                     /gene="xerD"
                     /locus_tag="VYP66_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1850326.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            8974..9702
                     /locus_tag="VYP66_000737"
     CDS             8974..9702
                     /locus_tag="VYP66_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1850327.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLVGRAQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            9721..10290
                     /locus_tag="VYP66_000738"
     CDS             9721..10290
                     /locus_tag="VYP66_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1850328.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            10277..10999
                     /locus_tag="VYP66_000739"
     CDS             10277..10999
                     /locus_tag="VYP66_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1850329.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            10999..11241
                     /gene="yidD"
                     /locus_tag="VYP66_000740"
     CDS             10999..11241
                     /gene="yidD"
                     /locus_tag="VYP66_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1850330.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(11466..12431)
                     /locus_tag="VYP66_000741"
     CDS             complement(11466..12431)
                     /locus_tag="VYP66_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1850331.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(12527..13279)
                     /locus_tag="VYP66_000742"
     CDS             complement(12527..13279)
                     /locus_tag="VYP66_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1850332.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(13276..14232)
                     /locus_tag="VYP66_000743"
     CDS             complement(13276..14232)
                     /locus_tag="VYP66_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1850333.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSFFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(14222..15181)
                     /locus_tag="VYP66_000744"
     CDS             complement(14222..15181)
                     /locus_tag="VYP66_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850334.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSILFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(15604..16305)
                     /gene="galE"
                     /locus_tag="VYP66_000745"
     CDS             complement(15604..16305)
                     /gene="galE"
                     /locus_tag="VYP66_000745"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1850335.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            16706..17770
                     /gene="pepA"
                     /locus_tag="VYP66_000746"
     CDS             16706..17770
                     /gene="pepA"
                     /locus_tag="VYP66_000746"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1850336.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            17792..18088
                     /locus_tag="VYP66_000747"
     CDS             17792..18088
                     /locus_tag="VYP66_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1850337.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AARLSGLVNRELLLNPKHPAPELLNLARFVKREEAKYRGTATSALMYEELFKML"
     gene            18770..19213
                     /locus_tag="VYP66_000748"
     CDS             18770..19213
                     /locus_tag="VYP66_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1850338.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            19217..19980
                     /locus_tag="VYP66_000749"
                     /pseudo
     CDS             19217..19980
                     /locus_tag="VYP66_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
     gene            19995..20723
                     /locus_tag="VYP66_000750"
     CDS             19995..20723
                     /locus_tag="VYP66_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850339.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKILLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVS
                     NPETILKAPATDFVADLFGGSIHD"
     gene            20716..22236
                     /locus_tag="VYP66_000751"
     CDS             20716..22236
                     /locus_tag="VYP66_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1850340.1"
                     /translation="MTNLIATFQDRFGDWLTALSQHLQLSLLTLLLAILLAIPLAVYL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            22581..23387
                     /locus_tag="VYP66_000752"
     CDS             22581..23387
                     /locus_tag="VYP66_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1850341.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(23553..24089)
                     /locus_tag="VYP66_000753"
     CDS             complement(23553..24089)
                     /locus_tag="VYP66_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1850342.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTGQEVVQFYLDLLIPKN"
     gene            24222..25112
                     /locus_tag="VYP66_000754"
     CDS             24222..25112
                     /locus_tag="VYP66_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1850343.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            25356..25709
                     /locus_tag="VYP66_000755"
     CDS             25356..25709
                     /locus_tag="VYP66_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1850344.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            25710..26747
                     /locus_tag="VYP66_000756"
     CDS             25710..26747
                     /locus_tag="VYP66_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1850345.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(26793..27800)
                     /gene="galR"
                     /locus_tag="VYP66_000757"
     CDS             complement(26793..27800)
                     /gene="galR"
                     /locus_tag="VYP66_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1850346.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTKLTLRESTLNQ
                     E"
     gene            27964..29142
                     /locus_tag="VYP66_000758"
     CDS             27964..29142
                     /locus_tag="VYP66_000758"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1850347.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            29161..30642
                     /locus_tag="VYP66_000759"
     CDS             29161..30642
                     /locus_tag="VYP66_000759"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1850348.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRIPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEHVGISLD"
     gene            30712..31116
                     /locus_tag="VYP66_000760"
     CDS             30712..31116
                     /locus_tag="VYP66_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1850349.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            31273..32127
                     /locus_tag="VYP66_000761"
     CDS             31273..32127
                     /locus_tag="VYP66_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV1850350.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            32153..32923
                     /locus_tag="VYP66_000762"
     CDS             32153..32923
                     /locus_tag="VYP66_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1850351.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMVLEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            32910..33776
                     /locus_tag="VYP66_000763"
     CDS             32910..33776
                     /locus_tag="VYP66_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HEV1850352.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(33863..35125)
                     /locus_tag="VYP66_000764"
     CDS             complement(33863..35125)
                     /locus_tag="VYP66_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1850353.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(35125..35706)
                     /locus_tag="VYP66_000765"
     CDS             complement(35125..35706)
                     /locus_tag="VYP66_000765"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1850354.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFSE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(36106..36201)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(36584..36712)
                     /locus_tag="VYP66_000766"
     CDS             complement(36584..36712)
                     /locus_tag="VYP66_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEV1850355.1"
                     /translation="MKANYPIYRPLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     gene            complement(36719..36970)
                     /locus_tag="VYP66_000767"
     CDS             complement(36719..36970)
                     /locus_tag="VYP66_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1850356.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            complement(36982..37809)
                     /gene="xth"
                     /locus_tag="VYP66_000768"
     CDS             complement(36982..37809)
                     /gene="xth"
                     /locus_tag="VYP66_000768"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1850357.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            37943..38398
                     /locus_tag="VYP66_000769"
                     /pseudo
     CDS             37943..38398
                     /locus_tag="VYP66_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            38551..38847
                     /locus_tag="VYP66_000770"
     CDS             38551..38847
                     /locus_tag="VYP66_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1850358.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            39053..40798
                     /locus_tag="VYP66_000771"
     CDS             39053..40798
                     /locus_tag="VYP66_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850359.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYTIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            40788..42539
                     /locus_tag="VYP66_000772"
     CDS             40788..42539
                     /locus_tag="VYP66_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850360.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMAYTL"
     gene            42712..43404
                     /locus_tag="VYP66_000773"
     CDS             42712..43404
                     /locus_tag="VYP66_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1850361.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            43447..44673
                     /locus_tag="VYP66_000774"
     CDS             43447..44673
                     /locus_tag="VYP66_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1850362.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            45177..45518
                     /locus_tag="VYP66_000775"
     CDS             45177..45518
                     /locus_tag="VYP66_000775"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850363.1"
                     /translation="MPYSSILEALHLFLSRLNLAFIEGLFKKYSVLVSIRHMSDIQVN
                     IPGECLYDKVFVLSFIIYNISTNLNIVNGIFYIQAKKDSITFEWKAKEQTRKLAIDSS
                     KPCFEVVDIVK"
     gene            45797..47956
                     /gene="pfbA"
                     /locus_tag="VYP66_000776"
     CDS             45797..47956
                     /gene="pfbA"
                     /locus_tag="VYP66_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1850364.1"
                     /translation="MVKNSKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDLKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            47940..48236
                     /locus_tag="VYP66_000777"
     CDS             47940..48236
                     /locus_tag="VYP66_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850365.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYNKMK"
BASE COUNT        14180 a         8910 c        10922 g        14224 t
ORIGIN      
        1 tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact ttttttctac
       61 acaaaatagg ctccataata tccatagggg ggttacccac tacaaatatt atagagccga
      121 aaaaggctga gatctggtgt ctcagtcttt tatttcttgc gttttgcaaa atctacaaat
      181 ctaaatttct ctaacttatg gcgactttcg gtaaactgaa attggcgtcc gtcttggaga
      241 tagacttttg atttaatcga aacgacataa gggtctttgc caatgtccat gagaatcttg
      301 tctcggtcgc ttgagtggtc aatggtgatt tccttctgag cataatcaat aaggagtttg
      361 aggccatttt ctatataaga atagatagac tgctcagcaa tttggcgagt gagatttgga
      421 attagttcca tatccagata gtccgtatcc agaacggata ccagatcatc caccacacgc
      481 tggcggacca ccttccaaac catccgaaac tctgggaaac cggttatcag tgaggatttt
      541 ttatcaataa taatcttgtc cagactgacc acgttggttt tagagcgcag tccaagttct
      601 ttaactagtt cttggtagct ggttaggttg gatacaggga aattgacggt ttcttctttg
      661 acgacttgag aaccttgccc tcttatcttt ttgatcaatc cttcctcttg gaggagagac
      721 agggcctttc ggacggtatc acgactcact tgatattgct ccataaggtc gtgctcgcta
      781 ggaaggaaat ctccgacagc gtaagtctcg ttttgaatgg tttcttggat ttgcttaaat
      841 aattgttggt atttcttcat tttgcctgct taaataggtt tttagtctag tttaatgaac
      901 acctgtatct attttaccat acaagtgcta gaaaatttac aaaaaaacac cctttttata
      961 ccaaacaagt tgcagacaag tttggtatcg tttacaatat acttatcaaa tcaaacttgc
     1021 tttgacaagt ataaggagaa tcaaatggga aaatttgaac aagaagccaa agatctgctt
     1081 caggcaattg gaggcaaaga aaatgtgact gccgtaactc actgtgcgac acggatgcgc
     1141 tttgttttag gagatgataa gaaggctaat gttaaagcta tcgagtcaat tccagctgtt
     1201 aaaggaactt ttacaaatgc aggtcaattt caggtaatca ttggaaatga cgtgcccatc
     1261 ttttataatg attttacagc cgtttcaggt attgagggtg tttccaaaga agcagccaag
     1321 tctgcagcta agagtaatca aaacgtggtc caacgtgtta tgaccactct ggcggagatt
     1381 tttactccga ttattccagc cttgatagtc ggaggattga tcctcggttt ccgtaatgtc
     1441 ttggaaggtg tccattggtc gatgttggat ggcaagacca tcacagaatc ctctcagttt
     1501 tgggcaggtg tcaatcactt cctctggttg cctggtgaag ctatcttcca gttcttacca
     1561 gtagggatta cttggtctgt ttctcgtaag atgggaacca gccaaatttt gggaattgtt
     1621 ctcggaatct gtttggtatc gcctcagttg ctcaatgcct atgcggttgc ttcaacgcca
     1681 gcagctgata tcgcagcaaa ctgggtttgg aattttggtt attttactgt taatcgtatt
     1741 ggttaccaag cccaagttat cccagccttg cttgcaggtt tgagtctgtc ttatcttgaa
     1801 attttttggc gcaaacatat cccagaagtc atttccatga tttttgtacc ttttttgtca
     1861 ttgattccag ccttgatttt ggctcatact gtcttggggc caatcggttg gacaattgga
     1921 caaggacttt catcagttgt attggcaggt ttaacgggtc ctgtaaaatg gctcttcggt
     1981 gcaatttttg gtgccctcta cgctccattt gtcatcacag gtctgcacca catgaccaat
     2041 gccattgata cacaattgat tgcggatgct ggtggcactg ccctctggcc tatgattgct
     2101 ctttctaata ttgctcaagg ctcagccgtg tttgcctatt atttcatgca tcgccatgat
     2161 gagcgtgagg ctcaggtttc acttcctgca accatttcag cctatctcgg tgttacagaa
     2221 ccagctcttt ttggggttaa cgtaaaatat atttatccat ttgttgctgg gatgactggt
     2281 tcagcccttg caggcatgtt atccgttact tttaatgtaa ctgcggcttc tattggtatc
     2341 ggtggtttgc caggtattct ctctattcaa cctcaataca tgctgccatt tgcaggaact
     2401 atgctagttg cgattgttgt tccaatgctc ttgactttct tctttcgcaa ggctggtctc
     2461 ttcacaaaaa tagagggcga tacgaacttg caggcagaat tcgttgctca agaagaagca
     2521 gaatttgtga gccatgaacc agtagaactt acttcggtag aaattatcag cccactaact
     2581 ggccaagtga aagaattgag tcaagcgacg gatcctgttt ttgcatcagg tgtcatgggg
     2641 caaggtctgg tcattgaacc aagccaaggt gagttgacct ctccagttaa tggaacagtg
     2701 acggttcttt tccctaccaa gcatgccatc ggcattgtct ctgacgaggg agttgaattg
     2761 ctcatccaca tcggtatgga tacagtaggt cttgatggca aaggttttga aagtcttgta
     2821 gtccaaggag atcacgttat agttggccag caactgattc gttttgatat ggatgtcatt
     2881 aaggctgcag gtctggtgac agaaactcct gttatcatca ccaaccaaga tgcttataca
     2941 gcgactatta ctggaactta tccgacaacg atccaagctg gagcatctct catggtcgct
     3001 acacgaatct aatactcttc gaaaatctct tcaaaccacg tcagctctat ctgcaacctc
     3061 aaaatagtgt tttgagcaac ctgtggctag cttcctagtt tgttctttga ttttcattga
     3121 gtataattga aatagcacaa atagggacgg aagactgctt cctccctttt atcagaaaag
     3181 gagaaacaga tgacacttga taaaggaaaa gtagtctatc aaatctatcc aaaatcttac
     3241 aaagacacca ctgaaaacgg tattggggat ttccgtggga ttatcgaaaa aattccctat
     3301 ttagccaaac taggtgtgga tatggtctgg ctcaatccat tctatccaag ccctcaacgg
     3361 gataatggtt acgatatttc agattatatg gcagtggatc ctctttttgg tgatatggct
     3421 gattttgagg aaatggtgtg tgtcggtaaa gagcacaaga ttgactttat gctggacatg
     3481 gtacttaatc attgttcgac agagcatgaa tggtttcaga aagccctagc tggtgataag
     3541 tattatcaag actttttctt catccaagac caaccaacag attggcagtc taagtttggt
     3601 ggttctgcat gggcgccttt cggggatact gggaaatact atcttcacct atttgatgag
     3661 acccaggctg accttaactg gcgcaatccc aatgtccgta aggagctttt caaggttgtt
     3721 aatttctggc gcgacaaggg tgtcaaaggt tttcgatttg atgtgatcaa tttgatcggt
     3781 aaggacgagg tttcagtgga ctgtcctgaa aatgaaggga agccagctta tacagacaaa
     3841 cccatcgttc ataactattt gcgtatgatg aaccaagcca cttttggatc tgacgatagc
     3901 tttatgacag ttggggaaat gtcttctacc accatggaaa actgtgtcct ttattcgtcg
     3961 cctgatcgtc aggaattatc catgaccttt aattttcatc acctcaaggt ggactataag
     4021 gatggacaaa agtggacctt ggctcccttt gattttgaag agttgaagag tctttaccat
     4081 agttggggta aggaaatgag tgataaagac ggttggagtg ccctcttttg gaacaatcac
     4141 gatcaaccac gtgccttgaa ccgttttgtc gatattcaaa acttccgcaa ggaaggagcc
     4201 accatgctag cagccagcat tcacctgtca cgtgggacac cttatatcta catgggtgag
     4261 gaaatcggga tgattgaccc agactatgat tctatggctg attatgtgga tgtcgaatcg
     4321 cttaatgcct atcagatgct cttagaagaa ggaaagagtc agcaagaagc cttccagatt
     4381 attcaagcta agtcgcgtga taattcacgt attcccatgc agtgggatac ttctgaaaat
     4441 gcaggatttt caacaggcac tccatggttg aaagtcggta aatcctataa agatatcaat
     4501 gtagaaaatg aaatcaaagg tctgattttc accttctatc aagacttgat tcgactgcgt
     4561 aaggaaatgc caatcatttc agaaggaaat tacaaaccag cctttgaaga tagcaaacaa
     4621 gtctacgctt ttgaacgcca gtttgaggat caaaagttac tagtgctcaa taacttttat
     4681 gccaaagaag tggaaatcga cttgccagca gtctaccaaa atggacagat tttgatttca
     4741 aactatgaag atgcagaagt gtctgagaaa attctactca aaccctatca aacactggct
     4801 atttatgtaa attaatactc ttcgaaaatc tcttcaaacc gtgtcagttt tatctgtaac
     4861 ctcaaagcgg tgctttgagc aacctgtggc tagcttccta gtttgctctt tgattttcat
     4921 tgagtataaa cttagcaagg agacctcttt ttcagaaaag cagggttctt tttgctgtct
     4981 attccatcct tgaaagtgta gaacaaactg gtcagggtgg ctagtttgtg gtataatgaa
     5041 agggattcaa aaagaaacag gagaaaaatg atggatttac ttttagcaat tgtattgatt
     5101 gtgctagctt ttctaggagg agctcttgga ggaatgtact tggttcgtaa gcaaatcgaa
     5161 aaagaatttg ctgacaaccc acgtttgaat gctgaagcag ttcgtactct tttgagtgca
     5221 aatggtcaaa aaccaagcga agctaaggta caacaagttt accaccaaat catccgccaa
     5281 caaaaggcag cccttgctaa caataaaaag aaaaaataaa taaggaaaag tctgggatga
     5341 aagttccaga cttctcacta tgttggttat ggtttaggga tgagactttt tccttgcatt
     5401 ctattgatat ttgattatga ttaagagaga ggtagttgac attctatcaa gctgtcggtc
     5461 agttcgttca gtacaaggaa tcataatgaa cgatcaatca gaaaaaagac tagaaagaag
     5521 actgtatgga taatcgacca attggttttt tggattcggg tgtcgggggc ttgaccgttg
     5581 tgcgcgagct catgcgccag cttccccatg aagaaatcgt ctatattgga gattcggcgc
     5641 gggcgcccta tggcccccgt cctgctgagc aaattcgtga atatacttgg cagctggtca
     5701 actttctctt gaccaaggat gtcaaaatga ttgtcattgc ttgtaacact gcgactgcgg
     5761 tcgtctggga agaaatcaag gctcaactag atattcctgt cttgggtgta attttgccag
     5821 gagcttcggc agccatcaag tccagtcaag gtgggaaaat cggagtgatt ggaacgccca
     5881 tgacggtaca atcagacata taccgtcaga aaatccatga tctggatccc gacttacagg
     5941 tggagagctt ggcctgtccc aagtttgctc ccttggttga gtcaggtgcc ctgtcaacca
     6001 gtgttaccaa gaaggtggtc tatgaaaccc tgcgtccctt ggttggaaag gtggatagcc
     6061 tgattttggg ctgtactcat tatccactcc ttcgccctat tatccaaaat gtgatggggc
     6121 caaaggttca gctcatcgat agtggggcag agtgcgtacg ggatatctca gtcttactca
     6181 attattttga aatcaatcgt ggtcgcgatg ctggaccact ccatcaccgt ttttacacaa
     6241 cagccagtag ccaaagtttt gcacaaattg gtgaagaatg gctggaaaaa gagattcatg
     6301 tggagcatgt agaattatga caaataaaat ttatgaatat aaggatgacc aggactggta
     6361 tgttgggtct tatagtattt ttggtggcgt taacagtttg agcgactatc agacagattt
     6421 tcctctgttt gaattctcca aaatatttgg agatgaagag tatggtttcc cgctttcagt
     6481 tactgtttta cgctatggtt ctacctaccg tttgttctcc tttgtggtag acatgcttaa
     6541 tcaagaaatg ggacgaaact tggaagttat tcaacgtcat ggggccctgc tcttggttga
     6601 aaatgggcaa ctcttgtatg tagaattgcc taaagaaggg gtcaatgttc atgatttctt
     6661 tgagacaagc aaggtcagag aaaccttgtt gattgcgact cgtaacgaag gtaaaaccaa
     6721 ggaattccga gctatctttg ataagttagg ctacgatgtg gaaaatctta atgactaccc
     6781 tgacctgcct gaagtagcag aaacaggtat gacctttgaa gaaaatgccc gccttaaggc
     6841 agaaaccatt tctcaattaa cgggcaagat ggttttggca gatgattctg gtctcaaagt
     6901 cgatgtcctt ggtggcttac caggcgtctg gtcagctcgt ttcgcaggtg tgggagcaac
     6961 tgaccgtgaa aataatgcca aactcttgca cgaattggcc atggtctttg aactcaagga
     7021 ccgctcggct cagttccaca caaccctagt cgtagccagc ccaaataagg aaagtttagt
     7081 tgttgaagca gactggtcag gttatattaa ctttgaacct aagggtgaaa atggctttgg
     7141 ctatgatccc ctcttccttg taggagagac aggtgagtca tcagctgaat taaccctgga
     7201 agaaaaaaat agtcaatctc accgtgcctt agccgttaag aaacttttgg aggtatttcc
     7261 atcatggcaa agcaaactat cattgtaatg agcgattccc atggcgatag cttgattgtg
     7321 gaagaagtcc gtgatcgcta tgtgggcaaa gtcgatgccg tttttcataa cggcgattct
     7381 gaactacgtc cgtattctcc actttgggag ggcatccgcg ttgttaaagg gaacatggac
     7441 ttctacgccg gctacccaga acgtctggtg actgagcttg gttcgaccaa gattatccaa
     7501 actcatggtc acttgtttga catcaatttc aactttcaaa agttggacta ctgggctcag
     7561 gaggaagagg ccgctatctg cctctatggt cacttgcatg tgccaagtgc ttggatggaa
     7621 ggcaagatcc tctttctaaa tccaggttct atcagtcaac cacgaggtac catcagagaa
     7681 tgtctctatg ctcgtgtgga gattgatgat agttacttca aagtggactt tttgacacga
     7741 gatcacgagg tgtatccagg tttgtccaag gagtttagcc gatgattgcc aaggagtttg
     7801 agactttctt gttggggcag gaggaaactt ttttgacccc tgctaaaaat ctagctgtgt
     7861 tgattgatac ccacaatgcg gatcatgcga ccctcttgct cagtcagatg acctataccc
     7921 gtgttcccgt tgtgacagat gaaaaacagt ttgttgggac gattggactc agagatatta
     7981 tggcttatca gatggagcat gacttgagcc aagaaatcat ggcggatacg gatatcgttc
     8041 atatgacaaa aacggacgta gcggttgttt cgcctgattt caccattacg gaggtcttgc
     8101 acaagctagt agatgagtcc ttcttaccgg ttgtggatgc agagggtatt ttccaaggga
     8161 ttattacgcg caagtccatc ctcaaggccg ttaatgccct cttgcatgac tttagtaagg
     8221 aatatgagat tcgatgccaa tgagagacag gatttcagcc tttttagagg aaaagcaggg
     8281 cttgtctgtc aattccaagc agtcctataa gtatgatttg gagcaatttt tagacatggt
     8341 aggtgagcgg atttctgaga ccagtctcaa gatttaccaa gcccagctag ccaatctaaa
     8401 aatcagcgcc cagaagcgaa agatttcggc ctgtaaccaa tttctatact ttctctatca
     8461 aaaaggagag gtggacagct tttaccgctt ggaattagcc aaacaagctg aaaagaagac
     8521 ggaaaagcca gagattctat acctagactc tttttggcag gaaagcgacc atccagaggg
     8581 ccgcttgcta gcgctcttaa tcctagaaat ggggctcttg cccagtgaga ttttagccat
     8641 caaggttgcg gacatcaatc tggattttca ggtgttgcga atcagcaagg cttcccaaca
     8701 gaggattgtc accattccca cggccttgct ttcagaattg gaacccttga tggggcagac
     8761 ctatcttttt gaaagaggag agaaacccta ttctcgtcag tgggcctttc gtcagttaga
     8821 atcttttgtc aaggagaaag gttttccatc cttatcagct caagtcttac gtgaacagtt
     8881 tattctaaga caaatagaaa acaaggtcga tttgtacgaa attgcaaaaa aattaggatt
     8941 aaaaacagtc ctgaccttag aaaaatatag ataatggata ttaaattaaa agattttgaa
     9001 ggacccctgg acttgctctt gcatctggtt tctaagtacc agatggatat ctacgatgtg
     9061 cccattacgg aagtcatcga acagtatcta gcctatgtct caaccctgca ggccatgcgt
     9121 ctggaagtga cgggtgagta catggtcatg gctagtcagc tcatgctgat taagagtcgt
     9181 aaactccttc cgaaggtagc agaagtgaca gacttggggg atgacctgga gcaggacctc
     9241 ctctctcaaa tcgaagaata tcgcaagttc aagctcttgg gtgagcactt ggaagccaag
     9301 caccaagaac gggcccagta ttattccaaa gcgccgacag agttgattta cgaagatgcg
     9361 gagcttgtgc atgacaagac gaccattgac ctctttttgg ctttttcaaa tatcctagcc
     9421 aagaaaaaag aggagtttgc acaaaatcac acgacgatct tgcgggatga gtataagatt
     9481 gaggacatga tgattatcgt gaaagagtcc ttggttggac gagctcaatt gcgcttgcag
     9541 gatttgttca aggaagccca gaatgtccaa gaggtcatca ccctcttttt ggcaacccta
     9601 gagttaatca aaacccagga gttgatcctc gtgcaagagg agagttttgg agatatctat
     9661 ctcatggaaa agaaggaaga aagtcaagtg cctcaaagct agacttgata gagaggaaag
     9721 atgagtactt tagcaaaaat agaagcgctc ttgtttgtag cgggtgaaga tgggattcgg
     9781 gtccgccagt tagctgaact cctctctctg ccaccgacag gcatccagca aagtttagga
     9841 aaattagccc agaagtatga aaaggaccca gattccagtt tggctttgat tgagacaagt
     9901 ggtgcttata gattggtgac caagcctcaa tttgcagaga ttttgaagga atactctaag
     9961 gcgcctatca accagagctt gtctcgggct gcccttgaga ccttgtccat tattgcctac
    10021 aaacagccga ttacgcggat agaaattgat gccatccgtg gagttaactc gagtggagcc
    10081 ttggcaaagt tgcaggcttt tgacctgata aaggaagacg ggaaaaagga agtattgggg
    10141 cgccccaacc tctatgtgac tacggattat ttcctagatt acatggggat aaaccattta
    10201 gaagaattac cagtgattga tgagcttgag attcaagccc aagaaagcca attatttggt
    10261 gaaaggatag aagaagatga gaatcaataa gtatattgcc cacgcaggtg tggccagtag
    10321 gagaaaagca gaagagctga ttaagcaagg cttggtgacg gttaacggcc aagtggtgcg
    10381 tgaactagca accactatca agtcaggcga caaggtcgaa gttgaaggtc aacctatcta
    10441 caacgaagaa aaggtctact atctgcttaa caaaccacgc ggtgtgattt ccagtgtgac
    10501 agatgataag ggtcgcaaga cggttgtcga cctcttgccc aatgtcaaag agcgtattta
    10561 ccctgtgggt cgtttggact gggatacatc aggtgtcttg attttgacca atgatgggga
    10621 ctttacagac gagatgattc accctcgtaa tgagattgac aaggtttatg tcgcgcgtgt
    10681 taaaggtgtg gccaataagg acaatctccg ccccttgacc cgtggtcttg agattgatgg
    10741 taagaaaacc aagccagctg tttatgaaat tctcaaagtg gacccagtca aaaatcgctc
    10801 tgtggtgcag ttgaccatcc atgaagggcg taaccatcag gttaaaaaga tgtttgaagc
    10861 tgttggtctc caagtagata agttgtctcg gactcgtttc ggacacctag acttgacagg
    10921 actccgtcca ggagaatccc gtcgtcttaa taaaaaagaa atcagccaac tacacaccat
    10981 ggctgtaact aagaaataat gaaacgaatt ttaatagcgc ctgtgcgctt ttaccaacgt
    11041 tttatctcac cagtctttcc accctcttgt cgctttgagc tgacttgttc caactacatg
    11101 attcaggcta ttgaaaaaca tggttttaag ggggtattga tgggcttggc tcggatttta
    11161 cgttgtcatc cctggtcgaa aacaggtaag gatcccgttc cagaccactt ttcccttaaa
    11221 cgaaatcaag aaggggaatg aggtggggta aatagatttc aaaatgataa aaacgcatcc
    11281 tatcaggttt gagtaaactt gataggatgc gttttagaat gtcaaaattt tatactcttc
    11341 gaaaatctct tcaaaccgcg tcagctttca tctgcaacct caaaacagtg ttttgagcaa
    11401 cctgcggcta gtttcctagt ttgctctttg attttcattg agtattaaat tgagtttgaa
    11461 gtggcttatt tcaaagcttt ttgtatgtct tcaatcatga gttttgttga ttcaagtccg
    11521 cctccgctta gataccagag gtctggtgtt agttggataa tcttaccatt tttagcagca
    11581 ggtgtttcag cgataagggc attttctagg acaccgtcgt tgctagagtt gtccccaccg
    11641 atggcaaggg tacggttgat gacaaagagg atgtcagggt tgatttcttt gacactttca
    11701 aagctgactt cttgtccgtg gcgtgagtct tcaaattttg tatcagttgg tttgaatttc
    11761 aaggtttggt acaagaaaga gaaacgagat ttggcaccaa aggctgccat ttttccttca
    11821 ttaaggagga tcgcaagggc ttttttgtca gagctttcat ttttagtagc gacttcttgg
    11881 atgctcttgt ctagcttggc caattcttcc ttggctttct gtgtaccagt ttcgccgaag
    11941 gcacttgcta aggattcgat attagccttg gtagaagtcc agtagtcatc cttgcttgct
    12001 tggaagagaa cggttggggc gatttctttg aatttgtcta cgaatttttg tgtacgtggt
    12061 gaagcgataa tcaaatcagg ctcaagggcg gcgatagctt ctaaatcagg ttctttcata
    12121 gaaccaacat ttttgacagt tcccactagg tcttttagat aagtcggaac agtttttgta
    12181 ggcattccga cgatattttt ttcaaatcct aaagcgcgaa tagtatccgc agcgccgagg
    12241 tcaaaggtca caatcttttc aggaactttg gaaagtttga cctcgtccag tgaactttta
    12301 atggttatct ctgttggagc agagctactg gtctctgtct gactagtgct tgagtttgta
    12361 ctacatgcac caagtaggag caagaagctg gccactaggg cagtgaaata aagtttaagg
    12421 gatgttttca taatttctcc tttttaaaat gtgataacga tttagggagt ctcttaatct
    12481 tattgactaa gagactgaag gttctctaac ttgagctttt atgttactag ctatagatac
    12541 agatcttttt gtcattgata tcagctagcg tgatgggaat ctcataaagt tgactgagca
    12601 ggtcagcctg catgatttga tcggttcttc ccttgctaaa gacctggccg tccttgaagg
    12661 cgacaatttc atctgcatac tgactggcca tgttgatatc gtggaggacg atgataatgg
    12721 tcttgccgag ttcctccacc agtcgtcgaa gaatctgcat catgctgacg ctttgcttga
    12781 tatcgagatt gttgagtggt tcgtccagca agataaagtc cgtatcctgg gccagtacca
    12841 tagcgataaa gacgcgctgg agttgccccc ctgacaggct attgatgtag cggtctttta
    12901 agttggtcag ttccaaatag ttcagagttt ctcggatttt ttcccagtct tctgatctaa
    12961 gtcgacctcg gctgtaggga aaacgtccaa aactgaccag ttcttcaaca gtcaatttgg
    13021 cttggtaatt gattttctgt tttaggatgg ttagttcttg ggccagttct tgcgaattcc
    13081 agctctcgat ttcacgtcct ttgatactga gaactccctg atctttcttg gttagtctgc
    13141 tcatgatgga gaggagagtc gattttccag caccatttgg accaataaag gctgtcagtt
    13201 tttgaggact gacttcaagc gaaatgcctt gcaaaatatc ctgtttttga atggatttgt
    13261 caatgttttc cagtttcact gacgagccct cctatatagt aagataaaga ataagaagcc
    13321 acccacactc tcaatgatca tactgatacg aatttccagt gcaaagactc gttcaatcaa
    13381 ggcttgcccc aaggttaagc taataaatcc aaccagaatg gccactataa agagtaactt
    13441 gtgctgatag tctttgacaa tcaggtaggt gaggttggcc agcataaagc cgaagaaggc
    13501 cataggtcct accaaggcag tggccgttga ggtcaaaagc acgattcccc agaggagctc
    13561 tttctgttct ttttcaacat cgagtcccaa tatctgagcc gtttctcttt gcaggtgcaa
    13621 gacatctaga acgactgctt ttcgaaagaa aaagattgtc aaagcgagga tgatcagaga
    13681 accgatggct aggatggaag tgttaagatg ttgaaaggag gcaaaaagac tattttgcag
    13741 tttatcgtat tcgtttggat ccattaggac ttgaaggaag gtgctgatat ttcgaaagag
    13801 acttctgagc gctagacaga tcagcaggat gaagaccagg tcttgcttca tcagtgtctt
    13861 caagtaacct tgtaaggcga gaaagaagaa ggactggaca agaagtaaga ctaggaattc
    13921 taagataggg gatttgccaa gttgaagaaa cttgctttca aaaaccagta gtagggtttg
    13981 tagtaggacg tagaaggatt caattcccaa aatactaggc gtcaggaagc gattttccgt
    14041 cagggtttga aaactaatgg tcgaaatccc agtcgcgatg gctaccaaga gataaacgat
    14101 gatcttttgg gaacgcaact tccaagcaaa ggctgacaag tgagtgatgg gccaaaagta
    14161 gagaagacaa gctccgatgg caagaataat gagaatccag aagagcttgg tatgtttgct
    14221 tttagtctgc atcttttcgt ccccctctcc agagaagtag gataaagacg agactaccga
    14281 tgattcctag caagagactg acagacaact catagggcct aatcagaact cgggatagga
    14341 tatcgcaagc cagaactaga ttggcaccaa ccagtgcgac catgagtttg gtttgactta
    14401 gattatctcc atagcgcttg cgaacaagat tgggaacgat aactccgaga aatggtaagc
    14461 cacccacggt aatcatggtg acgcttgtcg ttagcgccac cagaaagagg gccagttttt
    14521 caagtaggga gtaggaaatc cccaaactct cgctggtttc tttccctaga ttcatgatgg
    14581 tgaaggtttg ggataatttc caaacggtta tcaggatgat gaggcctaag aagagccact
    14641 catactgatg ggtctgaatc atggagaagg agccctgggt ccaggcagtc atactctgaa
    14701 ccagattgaa acgataggcg ataacttctg tgactgagcc gataatcccg ctatagatga
    14761 tcccaatcag aggcaacatc cacctttcct ttacagtaaa aatggtcata aaggctagga
    14821 agaagagggt gaatagaatg gatgaaacaa aagcgaagag catcttttgg gtcagactag
    14881 ccgatggaaa gacaaaaagg ctcagcacca ttcccagttt ggcggcttca gtcgttccaa
    14941 ctgtactcgg tgcagcaaac tgattttggg taatagtctg catgagaagg cctgccatac
    15001 tcatactaga ggcagtcagg agaatactga tagttcttgg gagacgggac tcttgaaaga
    15061 ggagccaggt ctgctggtcg aaatcaaata gctttcccca tgaaaaatca ctggtcccaa
    15121 tgctaataga gagaaagact aggagtagaa gtaagccaat taaataatga gaaagtttca
    15181 taccccgtcc tttcatgtag atttggtatc gaaagatacc tgcggatata aatgtaacat
    15241 tatttttcta atctgtcaat aaaatttctg acaatttaat aaatacaaca aggagagagc
    15301 aacaagactt tctcctttgt tatcctattc taaaatgttt ttaccttaat ctgataaaat
    15361 aatatcttcg agggagtagc tagccgtcca atcaagatat tgtttagctt ttgaagcatc
    15421 tgctaggaca ctggctgggt cactagcacg tcgagcaaca atctcgtgtg ggatttttta
    15481 atttagtaat tcttcagcag ttttaaagat ttctttgata gtatagcctt ttttagttcc
    15541 taagttaaag atttgagaag aactgtcttc ttgaaatagg tagttcattc ctttaacatg
    15601 agcctatgca aggtccaaga cataaatgta atctcgaata catgaaccgt cacgtgtatc
    15661 gtagtcatct ccaaatattt ttaagctatc attttgtccc aatgcggtct tgttgatatt
    15721 tggaatgatg tgagttggat ttttcacacg cagaccgttt gaagcatcca tttcagcccc
    15781 agcaacatta aagtaacgga aaataacata tttccagtcg tagcgattgg ccatccagta
    15841 aatcattcgt tcgcccatca gttttgtctc tgcataaggg ttgacagggt cgagcagggt
    15901 atcttcagtc accggcttgt caatacagtt atttccatag agagaagcag tcgaagagaa
    15961 catgattttt tgaatgccaa cttcagataa gactttgaga acttggttca taccagcaac
    16021 gttggcagtg aagtatttac ttggattttc aatactttcg ctcacaacaa tttcacctgc
    16081 acaatggagg acagcatcaa tctgattttc ttctaagtaa gcctttaagg cgctagcatc
    16141 ataaacatcc agttctttaa agctagcacg actatccaca gccgctcgat ttcctgtgga
    16201 gagattatcg aggacatgca cctgatagcc agcatttaaa agagctttaa cggtatggga
    16261 gccaatgtag ctagtcccac ctgtaacaag aattgttttg gtcatgattt tttccttttc
    16321 tagttttgta ctatagtaaa ttgaaataag atatgaacaa ctctattagg aaagtcaaat
    16381 taatttctag aaatgtttta gcagctacag cgtactattc caaactcaac caactatata
    16441 tttaaagaaa gaagaaaggg aagtcaacta ttttctgtaa atttcatgaa aaatccaaac
    16501 aactttgatg gtgtattgtt tttttgtttg gaaataaata ttcgaattaa ttttggaatg
    16561 tttactagat tttgcactac atgcaagaga atactatcct tttctaagat agagcaggac
    16621 taagatacta acttagaaat ccaccttccc actatccttc tcctataaaa agtggtaaaa
    16681 tggatgaaag aaagaaggaa ctgaaatgac aacattattt tcaaaaatta aagaagtaac
    16741 agaacttgct gcagtctcag gtcatgaagc gcctgtccgt gcttatcttc gtgaaaagtt
    16801 gacaccgcat gtggatgaag tggtgacaga tggcttgggt ggtatttttg gtatcaaaca
    16861 ttcagaagct gtggatgcac cgcgcgtctt ggtcgcttct catatggacg aagttggttt
    16921 tatggtcagc gaaatcaagc cagatggtac cttccgtgtc gtagaaatcg gtggctggaa
    16981 ccccatggtg gttagcagcc aacgtttcaa actcttgact cgtgatggtc atgaaattcc
    17041 tgtgatttca ggttctgttc ctccgcattt gactcgtgga aaggggggac caaccatgcc
    17101 agccattgcc gatatcgttt ttgatggtgg ttttgcggac aaggctgagg cagaaagttt
    17161 tggcatccgt cctggtgata ccattgtacc agatagttct gcaattttga cagccaatga
    17221 aaaaaatatc atctcaaaag cttgggataa ccgctacggt gtcctcatgg taagcgagct
    17281 agctgaagct ttatcgggtc aaaaactcgg caatgaactc tatctgggtt ctaacgtcca
    17341 agaagaagtt ggtctgcgtg gcgctcatac ctctacaacc aagtttgacc cagaagtctt
    17401 cctcgcagtt gattgctcac cagcaggtga tgtctacggt ggtcaaggca agattggaga
    17461 tggaaccttg attcgtttct atgatccagg tcacttgctt ctcccaggga tgaaggattt
    17521 ccttttgaca acggctgaag aagctggtat caagtaccaa tactactgtg gtaaaggcgg
    17581 aacagatgca ggtgcagctc atctgaaaaa tggtggtgtc ccatcaacaa ctatcggtgt
    17641 ctgcgctcgt tatatccatt ctcaccaaac cctctatgca atggatgact tcctagaagc
    17701 gcaagctttc ttacaagcct tggtgaagaa attggatcgt tcaacggttg atttgattaa
    17761 acattattaa accataaggg aggtggtagg gatggtagaa ccaaacctag aaagccttat
    17821 aaaagatctt tacaatcatg ctcgacatga tttgagtgaa gatttagttg ctgctctcct
    17881 agagactact aaaaaactgc ctactacaaa tgagcaattg caggcagctc gtctctcagg
    17941 cctggtcaat cgtgaattgc tcctaaatcc caaacatcca gcacctgagt tgctcaactt
    18001 ggctcgcttt gtcaaaagag aagaagccaa gtacagagga actgcgactt ctgcgcttat
    18061 gtatgaggaa ctttttaaaa tgctttgatt ccattgtgga tcaaagcatt ttttataaga
    18121 cttatctcgt gagcgttcaa atagtagtaa caaggaatca tgagaagtca gccgagacca
    18181 tagtagtgaa gaaacttctg taatggaagt ggagtgaagt gaggaatcgt caaacggtag
    18241 gggataggct gtttgaaggg tgctacgaaa aagatagggt aaggtgaaat tatagcggaa
    18301 tgaaataaga tatgaacaaa ttgattagga aaatcaaatg aatttataga aatcttttag
    18361 cagtcatggt gtcctattcc agtttcgaaa tgctataaat acgaacaaat tgattgggaa
    18421 attcaaatcg ctttctatca atgttttaga agatacagtg ctctagtcta acttcaatat
    18481 actataaaag aacagatgga agcaattatg atttacttct atctttaaaa taaatggtct
    18541 gataggaaaa atgtgtcccc tcataaaata taggatagta cgaatggaag gcttttgtag
    18601 actggaggac gaaggagttt agaaactctc gttaaaagtt agttgagccg gagtatggtg
    18661 gtgtggataa ttatcaaaaa ttatttccaa atcgaaatag ttgacagtta gaacgatgag
    18721 tgttacaatt attttattca tttcgatatc gaaataaatt ggaggtgtta tgaaagatag
    18781 tcatttgcta gcccatcata ttcgtttgtt gaatgggcgg atttttcaaa agttactgag
    18841 tcaagatcct gaggctcttt ataggggtga acagggcaag attttagcgg ttttatggaa
    18901 tagtgaaact ggctgcgcaa ctgcgacaga tatcgcgctt gcgactgggc ttgcgaataa
    18961 tacgctgacg actatgataa aaaagctaga ggaacaaaag cttgtaattg ttagtccgtg
    19021 tggaaaagac aagcgtaaga agtatttagt tttaacggag ttaggcaagt cccagaaaga
    19081 agtggggcat cgtgtcagtc agaaattgga tactatcttt tacaaaggat tttcagagga
    19141 agaaattcac caatttgaag gttttcaaga aagaattttg gcgaatctga aagagaaggg
    19201 aaatgaggtt tagaatatgt cacaacaagt gaaaaatgct cacaacctat acatccatgc
    19261 cattcaagac gggcgagttg ctgaggctca agcccagtct gtaggggata cctatatcca
    19321 aattcgacag gtgttcctga cgggaaagaa ggatttgcag ccttctttgc agatttcttt
    19381 gagcgtcatc cagagcgtca gattaagatt gtccgcacca ttgaggatgg caatctggtc
    19441 tttgttcatg ttcatcaata tctgaatggt ggagaagctc aatgggtgac gacggatact
    19501 ttccgtgagg atgagaatgg ttgtattgtt gagcattggg atgtcattga ctactatcga
    19561 acacctgaaa atgaccaact agatcaaatt tttggagatt ttgaaatcaa ggatttggat
    19621 aagaaagcag aaaataaaaa gctggttcgc cgtttcttga cagaaatttt ccaaaatggg
    19681 gagctagagc agtggagtga ttatgtggca gacgatttga ttcagcataa tcatgagatt
    19741 ggacaaggaa gtgctgctta taaaaactat gtggctgaat atagtgtcac ttttgacttt
    19801 gttttccaac tcttaggaca aggaaactat gtggttagct atggtcagac tcagattgat
    19861 ggcgttgctt atgcccagta cgatatcttc cgtttagaga acgggaaaat tgtggagcat
    19921 tgggataata aggaagtcat gcctaaggta gaagacttga ctaatcgagg gaagttttaa
    19981 attgaggaca aagaatgatt gaatacaaaa atgtagcact gcgctacaca gaaaaggatg
    20041 tcttgagaga tgtcaactta cagattgagg atggggaatt tatggtttta gtagggcctt
    20101 ctgggtcagg taagacgacc atgctcaaga tgattaaccg tcttttggaa ccaactgatg
    20161 gaaatattta tatggatggg aagcgcatca aagactatga tgagcgtgaa cttcgtcttt
    20221 ctactggtta tgttttacag gctattgctc tttttccaaa tctaacagtt gcggaaaata
    20281 ttgctctcat tcctgaaatg aaggggtgga gcaaggaaga aattacgaag aaaacagaag
    20341 agcttttggc taaggttggt ttaccagtag ccgagtatgg gcatcgctta cctagtgaat
    20401 tatctggtgg agaacagcaa cgggtcggta ttgtccgagc tatgattggt cagcccaaga
    20461 ttctcctcat ggatgaaccc ttttcagcct tggatgctat ttctcgcaag cagttgcagg
    20521 ttctgacaaa agaattacat aaagagtttg ggatgacaac gatttttgtg actcatgata
    20581 cggatgaagc cttaaagttg gcagatcgta ttgctgtttt gcaggatgga gagattcgtc
    20641 aggtgtcgaa tcctgagact attttaaaag ctcctgcaac agactttgtt gcagacttgt
    20701 ttggaggtag tattcatgac taatttaatt gcaacttttc aggatcgttt tggtgattgg
    20761 ttgacagccc tatctcaaca tttgcagttg tcacttttga ccttgttact agctattttg
    20821 cttgcgattc ccttggctgt ttatcttcgc tatcatgaga agttggcgga ttgggtctta
    20881 cagattgcag ggattttcca gaccatcccg tctctggcct tgttgggact ctttattccc
    20941 ttgatgggaa ttgggacttt accggcattg acagctctag tgatttatgc gatttttccg
    21001 attttacaaa atactattac tgggctgaag ggaattgatc cgagtcttca agaggctggg
    21061 attgcctttg ggatgaccag atgggagcgt ctcaagaagt ttgaaattcc acttgccatg
    21121 cctgttatca tgtctggaat tcggacggca gcggtcttga ttatcggtac ggctaccttg
    21181 gcgaccttga ttggggcagg gggactgggt tcctttatcc tgttgggaat tgaccgtaat
    21241 aatgccagtt tgattttgat tggggccctt tcttctgcag tgctagctat tgcctttaac
    21301 ttcctactaa aagtaatgga aaaagcgaaa ttgcggacga ttttctctgg ttttgccttg
    21361 gtggctttat tactgggtct gtcttatagt ccagcccttt tggctcaaaa agagaaggaa
    21421 aacttgatta ttgctgggaa aataggccca gaaccagaaa ttttggctaa tatgtataaa
    21481 ttgctgattg aagaaaatac cagcatgact gcgactgtta aaccgaattt tgggacgaca
    21541 agtttccttt atgaagctct gaaaaaaggt gatattgaca tttatcctga atttaccggt
    21601 acggtgactg aaagtttgct tcaaccatca cccaaggtga gtcatgagcc agagcaggtt
    21661 tatcaagtgg cgcgtgatgg cattgccaag caggatcatc tagcctatct caaacctatg
    21721 tcttatcaaa atacctatgc tgtagctgtt ccgaaaaaga ttgctcaaga atatggcttg
    21781 aagaccattt cggatttgaa aaaagtggaa gggcagctga aggcaggctt tacgcttgag
    21841 tttaacgacc gtgaagatgg aaataagggc ttgcaatcaa tgtatggtct caatctcaat
    21901 gtggcgacta tgcagccagc tcttcgttat caggcaattc agtcagggga tattcaaatc
    21961 acggatgcct attcgactga tgcggaattg gagcgttatg atttacaggt cttggaagat
    22021 gacaagcaac tcttcccacc ttatcaaggg gctccactca tgaaagaagc tcttctcaag
    22081 aaacacccag agttggaaag agttcttaat acattggctg gtaagattac agaaagccag
    22141 atgagccagc tcaactacca agtcggtgtt gaaggcaagt cagcaaagca agtagccaag
    22201 gagtttctcc aagaacaagg tttgttgaag aaatgatggg acagagactt taaacatact
    22261 gaactcaact tccttaaacg actagataaa agaatgctca gacaatttcg tctgggcttt
    22321 tttgatgtga gaatgactga atgtcactta aaatggaaag aaagagaaaa ttttcatgat
    22381 tttctaaaat tttactgtaa agacagttga ctattcataa aataggtgta taatattttg
    22441 tgaactactt aacaaataag aggtttcagc tcatgtcgac taaggttaga aatcttgtgt
    22501 ataggcagtt cattatctaa tagagcgttg cgtccgaaag tctatccaga cacggctctt
    22561 taaaaacaaa aggagaaatg atgcatactt atttgcaaaa gaaaattgaa aatatcaaaa
    22621 caaccctagg tgaaatgtca ggtggttacc gtcgtatggt tgcggctatg gctgatttag
    22681 gattttcagg aactatgaag gctatctggg atgacctctt tgcccatcgt agttttgccc
    22741 agtggattta tttgctggtt ttaggaagtt ttcctctctg gctggagttg gtttacgaac
    22801 atcgtattgt tgactggatt gggatgattt gtagcttgac agggattatc tgtgtaatct
    22861 ttgtatcgga aggtcgagca agtaattatc tttttggctt gattaactct gttatttacc
    22921 ttattttggc cctacagaaa ggcttttatg gtgaggtgct gacgacactt tacttcacag
    22981 tcatgcagcc aattggactt ctagtttgga tttatcaggc acagtttaag aaggaaaagc
    23041 aggagtttgt cgcgcgtaaa ctggacggca agggctggac aaagtatctt tccattagtg
    23101 tgctttggtg gttggccttt ggcttcattt atcagtctat tggtgccaat cgtccctatc
    23161 gtgattcaat cacagatgca accaatgggg tagggcaaat cctcatgaca gctgtttacc
    23221 gtgaacagtg gatattctgg gcggctacca atgttttttc aatctatctc tggtggggag
    23281 aaagcctgca aattcaaggg aaatatctaa tttatctcat taacagtcta gttggttggt
    23341 atcaatggag caaggcagct aagcagaata ctgatttact taactaggaa aagatgtttg
    23401 aaagtgctgt tttgagattt cgattaaaac agatatagtt gataatcaag gatttatagt
    23461 atgaaaaaga ggatcggcgg gtcctctttt gttgttgaaa agataaaaaa ctcagtaacc
    23521 tagaaataag acaactgagc tttactctat attcaatttt taggaatgag aaggtctaga
    23581 taaaattgga caacttcctg gcctgtgaaa tcttgacctt ttttgagcca ccaggtcaat
    23641 gtctcgataa agttggacac gaccaagtgt tggaggtaag aagtaggcat attagggtgg
    23701 gcttctttta aattatcagc tagcacggaa tagacatggt gttctagctc tttatggagt
    23761 tgacggagga agtagtcatt tttggaaaat agcagactgg tgatatggtc ttggttttta
    23821 tgaaaatgga gaaagaggtg ggcgaggtag tcctcggttg aaatggcttg ctctctttca
    23881 aaaagatgat ggaagaggta gcggcagagc tggtccagaa gaagctcctt actttcatag
    23941 tgacagtaaa aggtggatct tcccacatct gcgagatcaa tgatatcctg aacagtagtg
    24001 gcctcgtagc ccttagcatt caaaagttgt ataaaagctt gatagatggc ttttttggtt
    24061 ttgctgatac ggcggtcaat gttagtcata tggacactta aggcaaattg ttcagaactg
    24121 aataaagctg acgttttgct tctatccttt ctttgagttt tagtggataa tgataatgaa
    24181 caaggtgttc ataaatctat tataacaaag gaatgagaaa tatgaaggca aaatatgctg
    24241 tttgggtggc ttttttctta aatttgactt atgccattgt tgagtttatt gcaggtggag
    24301 tatttggttc tagcgctgtt cttgctgact ctgtgcatga cttgggagat gcgattgcaa
    24361 ttggaatatc agcttttcta gaaacaatct ccaatcgtga agaagacaat cagtacacct
    24421 tgggctataa gcggtttagc ctgctaggag ccttggtaac agctgtgatt ctcgtaacgg
    24481 gctctgttct agtcattttg gaaaatgtca cgaagatttt gcatccgcaa ccagtcaatg
    24541 atgaggggat tctctggtta ggaattattg cgattactat caatctgtta gcgagtctgg
    24601 tggttggtaa gggaaagaca aagaatgagt ctattctgag tttgcatttt ctggaagata
    24661 cgctagggtg ggtagctgtt atcctgatgg cgattgttct tcgatttacg gactggtata
    24721 tcctagatcc tcttttgtcc cttgtcattt ctttctttat tctttcaaaa gcccttccac
    24781 gtttttggtc tacactcaag attttcttgg atgctgtgcc agaaggtctt gatatcaagc
    24841 aagtaaagag tggcctggag cgattggaca atgtggccag ccttaatcag cttaatctct
    24901 ggactatgga tgctttggaa aaaaatgcca ttgtacatgt ttgtctaaaa gaaatggaac
    24961 atatggaaac ttgtaaagag tctattcgaa ttttcctaaa agattgtggt tttcaaaata
    25021 ttaccattga aattgatgct gacctagaaa ctcaccaaac ccataagcga aaggtgtgtg
    25081 acttggaacg gagttatgag catcaacatt agaaaaaagt gaaaaatact tgggtactat
    25141 cttatttgga atagagtaat ttctttatta tttaaatatt tcaaaaattg gtaagagaag
    25201 agcattgtat aaactccaga tatatgattg ttaatgataa aaatttttcg attagataca
    25261 aaatgcttga cttggagtca actcaaagtt atataataag ataagtgagt tagaatagcg
    25321 tgaattcagt gaatgaaatg agaggaggtt agcgtgtgaa tattaaatct gccagtgatt
    25381 tgttgggaat ttcagcggat acgattcggt attatgaacg ggttggtctt gtgccaccga
    25441 ttactcgtac tgctactggg attcgtgatt ttcaagatca ggatatcgaa gcgctggaat
    25501 ttattaagtg ttttcgttcg gcgggtgtct ctgtagatag tttagttgac tatatgtcgc
    25561 tctaccaaaa gggagatgaa acgagagagg agaggcttgg tattttagaa gaggaaaagc
    25621 aaaaattaga ggagcgcttg tctcagctac agacagcttt aaatcgttta aatctcaaaa
    25681 ttaaacttta taaggaagga aaattttaaa tgaaatcagc agtatataca aaggcaggtc
    25741 aggttggact tgctagcatt gaacgtccgc aaataataga agcggatgat gtgattattc
    25801 gtgtggttcg tgcgtgcgtt tgtggttcag atttatggag gtaccgtaat ccagaaacga
    25861 aagctggaca taaaaatagt ggacacgaag cgattgggat tgttgaagaa gctggggaag
    25921 ccattacgac ggtgaaacca ggtgattttg tgattgtccc ttttacacat ggatgtggtg
    25981 agtgtgatgc ctgtcttgct ggatttgacg gttcttgcga caatcatatt ggtaataatt
    26041 tggggggtga ttttcaggca gaatatattc gcttccacta tgcaaactgg gcgctggtta
    26101 aaatccctgg tcaaccttct gattatacag aagggatgct caagtccctt ttgactcttg
    26161 cagatgtcat gccgacaggc tatcatgcag cgcgtgttgc aaatgttcaa aaaggggaca
    26221 aggttgttgt tatcggtgat ggggctgttg gtcaatgtgc tgtcatcgcg gctaagatgc
    26281 gtggagcatc acaaattatc cttatgagcc gtcatgaaga ccgtcaaaag atggctatgg
    26341 agtcaggtgc gacagctgtt gttgcagaac gtggtcaaga aggaattacc aaggtgcgtg
    26401 aaatcctcgg cggaggagca gacgcagcac ttgaatgtgt tggtacggag gctgctatag
    26461 aacaggcgct aggtgttctt cataatggag ggcgtatggg ctttgtagga gtcccacact
    26521 ataataatcg tgctcttggt tcgacattta tgcaaaatat ctctgtagca ggtggggcag
    26581 cttctgctac aacatacgat aagcaatttt tactaaaagc cgtccttgat ggtgatatca
    26641 atccaggtcg cgtctttact tcaagttata aactggaaga tatcgaccaa gcctataaag
    26701 atatggatga acgtaagaca attaagtcta tgattgtaat cgaataaaaa acgaatagga
    26761 gttttagaac tctattcgtt ttttatgtta tcctattctt gatttagggt actttctctt
    26821 aacgtcagtt tggttcccaa catggtcagg ctaggtattt tccgaccgtg gagtacttct
    26881 ttgttaagaa tatccatacc tgctcgcccc atttcttcag tataaactgt aatactagag
    26941 aggggaggat agacctgttt ggtcagactg gtgtcgttga atgaaatgag gctgacgcga
    27001 tctggcaggc tgattccagc ttcttggagg gcacggaggg caccgatagc taaactatcg
    27061 ctggctgcga aaaatgctgg cggaagttgg tctcccaagc tctgaatggc ctccttcatt
    27121 aagtcatagc cagactgggc agtaaatctt ccttgaaaga ccagttcatc atgatagatt
    27181 cccctcgctt gactgtagtt tttgaagttt tctagacgct tgtcctgaat gatttcttct
    27241 tggtctgttg tttcctcaag ccctgttaga atcccgatgc ggtccatccc ttgactgagg
    27301 aaataatcga caacctgttt catagcagtg taaaaatccg tgataataca ggtatgtccc
    27361 agggaaagtg tatcgctgtc tagaaataca agaggctttt ggtattcttc aaaggcagaa
    27421 atctgagctc gactaaactt tccgatgcag agaatcccaa tcacttcctc gcttagggta
    27481 aaagggtggt cattaaaata gcgcaagata tcgtagtcca actcttgggc tcttttttct
    27541 attcctaggc gaatctggta gtagtagagg tcgtctagct ccccttgttc gctgacccat
    27601 tgaataatgg caatcttttg cttgggttta tgggactcgc ctgtcttgag gtgcttggtg
    27661 tagcccagct cttcagcaac ggttaaaata cggtgtctgg tttcttctgt aacagatagg
    27721 ctctggtcgc ggttgaggac acgggatacg gtcgcgatag agacagaggc tagctgtgca
    27781 atgtctttta aggtagccat aaatcctcct tgattaggtt agtatatcat atttttctgc
    27841 tttttactga tagtttagta aaattttagt aaaaaggatt gaccttggga aatcccttgg
    27901 atacaataga agaaaacgat tacacgttaa ggtggcttaa cggacagtca aaggagaaat
    27961 catatgacac aacatcttac tgctgaaact cttcgcaaag actttcttgc tgtttttggt
    28021 caagaagcag accaaacttt cttttcacca ggccgtatta atttgattgg tgaacacaca
    28081 gactacaacg gtgggcacgt ttttccagct gctatttcct taggaactta tggtgcagct
    28141 cgcaagcgtg atgaccaagt cttgcgtttc tactcagcta actttgagga caagggcatt
    28201 atcgaagtgc ctctcgctga cctcaagttt gaaaaagagc acaactggac caattatcca
    28261 aaaggtgtcc ttcatttctt gcaagaagct gggcacgtga ttgacaaagg ttttgatttt
    28321 tatgtttatg ggaatatccc aaatggtgct ggtttgtctt cttcagcatc ccttgaactc
    28381 ttgacagggg tagtggcaga gcatctcttt gatttaaaat tagagcgtct cgatttggtt
    28441 aaaatcggaa aacaaacaga aaataacttt atcggagtaa attctggcat tatggaccaa
    28501 tttgctattg gtatgggggc tgaccaacgt gctatttact tagataccaa tactttagaa
    28561 tacgacttgg tgccacttga tttgaaggac aatgtcgttg ttatcatgaa caccaacaaa
    28621 cgccgtgaat tggcggactc taaatacaat gaacgtcgtg ctgagtgtga aaaagcagtg
    28681 gaagaattgc aagttgcctt ggatattcag accctgggtg aattggacga gtgggccgtt
    28741 gaccaatata gctatctgat taaagatgaa aatcgtttga aacgtgctcg ccatgctgtg
    28801 cttgaaaacc aacgtaccct taaagctcaa gcagcccttc aagcaggtga tttggaaaca
    28861 tttggtcgtt tgatgaatgc gtcacacgtt tctctggagc atgattatga agtaactggt
    28921 ttggaattgg atactcttgt tcacacagct tgggcacaag aaggagttct cggtgctcgt
    28981 atgacagggg ctggttttgg tggctgtgcc attgccttgg ttcaaaaaga tactgttgag
    29041 gcctttaagg aagctgtagg caaacactac gaggaagtag ttggatacgc tccaagcttc
    29101 tatatcgctg aagttgcagg tggcactcgc gtccttgact agtcaaaagg aggctctata
    29161 gtgaccttag tagataaatt tgtaacacat gtcatttctg aaagttcatt tgaggaaatg
    29221 gatcgaatct acctgaccaa tcgtgttttg gcacgagtgg gagaaggtgt tttggaagtt
    29281 gagaccaatc tggataaatt gattgacctc aaggaccagc tagttgagga agccgttcga
    29341 ttagagacga ttgaggatag tcagactgcg cgtgaaatcc ttggtactga actgatggac
    29401 ttggtgactc cttgtccgag tcaggtcaat cgtgacttct gggaagccta tgcctactct
    29461 cctgagcaag cgatagagga tttttatcaa ctcagtcgga aaaatgacta catcaaactc
    29521 aaggccattg ctaaaaatat cgcttatcgt attccatctg attatggaga acttgaaatt
    29581 accatcaatc tctctaagcc tgaaaaggat ccgaaagaga ttgcggtagc caagttggtg
    29641 caagctagta attatcctca gtgtcaactt tgtttagaga atgagggtta ccatggtcgg
    29701 gtcaaccacc cagctcgcag caaccaccgg attatccgtt ttgaaatggt tggtcaggaa
    29761 tgggggttcc agtattcgcc ctatgcttac tttaatgagc attgtatctt tttagatggt
    29821 cagcatcgtc ccatggccat tagtcgtcag agttttgaac gtctgttggc tatcgtagag
    29881 cagtttccag gatattttgc tggatctaat gccgacctgc cgattgtggg gggctctatt
    29941 ctaactcatg atcattatca gggaggccgt cacgtatttc ctatggaatt ggctcccttg
    30001 caaaagacct tccgatttgc tggttttgag caggtcaagg ctggaattat caagtggcca
    30061 atgtctgtcc tacgcttgac ttcggattcc aaagaggatt tgattaactt agctgataag
    30121 attttccagg aatggcgtca gtattcagat tctagtgtgc agattttggc agagacagac
    30181 gggacaccgc atcacaccat cacaccaata gcgcgtaagc gtgatggaca gtttgagttg
    30241 gacttggtct tgcgagacaa tcagacttca gcagagcatc ctgatggcat ctatcatccc
    30301 cacaaggatg tccaacatat caagaaggaa aatatcggct tgattgaggt catgggcttg
    30361 gcaatcttgc caccacgtct gaaagaagaa gtggagcaag tcgctagcta tcttgtagga
    30421 gaagctgtta cagttgccga ttatcatcag gagtgggcag accaactcaa atcccaacat
    30481 ccagacctaa cggataaaga aaaagccctt gcaatcgtca aggactctgt gggtgctatc
    30541 tttgtgcgtg tacttgagga tgcaggagtc tacaagcaga cagaacaagg gcagacagcc
    30601 tttatgcgct ttgtggaaca tgtcggaatt tcactagact aggagctttc tccttgcaca
    30661 gtcctataaa aagtagtatc atagtgtcgt ttgaaatatc aggaggaaac gatgaaagac
    30721 tttcattttg acgctatatc tgcctttgaa aattacgaaa ttgaaaaaat gagagatggt
    30781 cacgttgtgg tgacgaccaa agtagtgaac tcgtcgctca actactatgg caatgcccat
    30841 ggtggctatc tattcacgct atgtgaccaa atcagtggtt tggtggttat ctcgctggga
    30901 cttgatgggg tgacactcca atcctctatc aactacctta aggcaggaaa actcgacgat
    30961 gtattgacca ttaaaggaga atgtgtccat caaggccgta caacctgtgt gatggatgtg
    31021 gatatcacca atcaagaggg cagaaatgtc tgtaaagcaa cctttaccat gtttgtcaca
    31081 ggccagcggt cagaagaaag acaggtaagg atataaagag taatttaata gagtgaggtg
    31141 aattttggaa tttataagat ttgccttact cattttttga tattgatatg atttaattct
    31201 aaaatagaaa atttagtaat gtggtagaaa atacaagagt tgtgttttaa tttctatggt
    31261 ataattaaaa gcatgaagat aaaagaaata aagaaagtta ctttacaacc gttcacgaaa
    31321 tggacaggtg gtaaaagaca attattgcct gttattagag aattaatgcc taaaacctat
    31381 aacaggtatt tcgaaccttt tgttggaggt ggagctttat tttttgattt ggctcctaaa
    31441 gatgcagtta ttaatgattt taacgctgaa ctaataaatt gctatcaaca aattaaggac
    31501 aatcctcaag aattgattga aattttgaaa gttcatcagg aatataattc aaaagaatat
    31561 tatttagatt tacgttctgc agatcgtgat gaaagaatag atatgatgtc cgaagtacaa
    31621 agagctgcac gtattctata tatgttgaga gtgaacttta atggtctata tcgtgtgaat
    31681 tctaagaatc aatttaatgt tccatatgga cgttataaga atcctaaaat tgttgatgag
    31741 gaattgatat ctgctatttc agtttatata aataacaatc aactagaaat taaagtggga
    31801 gattttgaaa aggcaattgt agatgttcga acaggagatt ttgtgtattt tgaccctcca
    31861 tatattccat tgtctgagac gagtgcattt acgtcttata ctcatgaggg attctctttt
    31921 gcagatcaag taagattaag agatgccttt aagagattga gtgatacagg agcttatgtt
    31981 atgttatcaa attcttctag tgctttagta gaggagttgt ataaggattt taatatacat
    32041 tatgttgaag ctacccgaac taatggagca aaatcttcaa gtcgaggaaa aatttctgaa
    32101 attatagtca caaattatga aaaataacga atataagtat ggaggtgttc ttatgacaaa
    32161 accatactac aataaaaata agatgattct tgttcattca gatacgttca agttcttatc
    32221 aaaaatgaaa ccagaaagta tggatatgat ttttgctgat ccaccttatt ttttaagtaa
    32281 tggtggaata tctaattctg ggggacaagt tgtttctgtt gataaaggag attgggataa
    32341 aatttcttca ttcgaagaaa aacatgagtt taatcgtaaa tggattcgcc tagcaaaaga
    32401 agttctgaag cctaatggga cggtatggat ttcaggtagt ttgcacaaca tatactcagt
    32461 tggaatggta ttagaacaag aaggttttaa aattctgaat aatattactt ggcagaaaac
    32521 aaaccctgcc cccaatttat cttgtcgtta ttttacccat tctactgaaa ccattttatg
    32581 ggccagaaaa aatgataaaa aagctcgtca ttactacaat tatgatttaa tgaaagaatt
    32641 gaatgatgga aaacaaatga aagatgtctg gacgggttct ttaacaaaga aagttgaaaa
    32701 atgggctggg aaacatccaa ctcaaaaacc agagtatttg ttagaacgca ttattttagc
    32761 ctctactaaa gagggtgact atattctaga cccatttgtt ggtagtggca ctacgggtgt
    32821 tgttgcgaag cggttaggta gaagatttat aggtatcgat gctgaaaaag aatatttaaa
    32881 aattgcaagg aagaggttgg aggcagaaaa tgaaacaaac tagaaatttt gatgagtggt
    32941 tgtcaacgat gaccgacaca gtagctgact ggacttatta tacagatttt cccaaggttt
    33001 ataaaaatgt atctagtata aaagttgctc taaatattat gaatagtctt attggtagta
    33061 aaaatataca agaggatttt ttagacttat atcaaaatta tccagaaatt ttgaaagttg
    33121 tgcctctact tattgctaaa cgtttgagag atacgattat tgttaaggat ccgataaaag
    33181 atttctattt tgattttagt aaacgaaact atagtattga agaatatact atgtttttgg
    33241 aaaaatcagg tatatttgat ttattgcaaa atcatttagt atcaaattta gttgactacg
    33301 ttacaggtgt tgaggttggt atggatacta atgggcgcaa aaatcggact ggagatgcga
    33361 tggaaaatat tgttcaaagt tatcttgaag ctgaagggta tattttagga gagaatttat
    33421 ttaaagagat tgaacaaaat gaaatagagg aaattttttc tgtcgattta tctgctatta
    33481 cgaatgatgg gaatactgtg aaacgttttg attttgtcat aaaaaatgaa caagtgcttt
    33541 atctgattga ggttaatttt tattcaggaa gtggttcaaa attaaatgag acggctagat
    33601 cttacaaaat gattgctgaa gaaattaaag ctattcctaa tgttgagttt atgtggatta
    33661 ctgatggaca aggttggtat aaggctaaga ataatttacg agaaacattt gatattttac
    33721 cattcttata taatattaac gatttggaac ataatatttt aaagaatttg aaataggtcc
    33781 aattcaatta gatgggaatt gggattgatt gtatttataa tcaatttgtg ataaacaaaa
    33841 aagaggctcg cacctctttt tcttatttct ttttatgatt taatacggca ttgaggacaa
    33901 tggcgagtag gctggctacg acgattccgt ttgagaagaa catttggaag gctgtcggca
    33961 tgctgacaaa gagattactg ttgttgagac cgacacctgc agcgattgaa acagctgcga
    34021 taaggaagtt gtgttcattg ttagcaaagt caactcgggc taggatttgc atcccttgaa
    34081 tagatacaaa accaaacatc accagcatgg caccgccgag gacggagctt ggaatgattt
    34141 gggcaagggc accaaactta ggaagcagtc caaggagaac caggaaacca gctgcgtagt
    34201 agattggcag gcgttttttg atgcctgaca atttaaccaa accaacgttt tgtgaaaatc
    34261 cggtgtaagg gaaggtgtta aagattcctc cgagaagtac ggccaaacct tctgcgcggt
    34321 aaccgttgcg aaggcgcgtg ctgtcgattg gatcttttgt gatatcagac aaggctagat
    34381 aaacaccagt tgactcaacc atagacaccg ttgcgatgat acacatcatg gcaatagatg
    34441 agatttcaaa ggttggcatc ccaaagtaga gtggagttgg gacatggaca agtggagcta
    34501 ccgcaacagg agagaagtcc accaagccca tagtagcagc aatggcagtt ccaacaacca
    34561 gaccaatcaa aatagagata gacttgataa atcctttggt aaagatgttg atcaagagga
    34621 taatcagaac agtaatagct gcaagcaaga gactttgacc agttggctct ggaacgttat
    34681 ttcccatatt tccaatagcg acagggatca aggttaaacc aatcgtggta ataacagatc
    34741 ctgttacgat agatgggaag agattggcta cttttgagaa gatgcctgaa acaagaacca
    34801 cgtaaatccc agatgcgata agggcaccaa acatagcgcc actaccatgg ctttgcccaa
    34861 tcataatcaa gggagcgacc gactggaatg caactccaag aacgactggg agtccaatcc
    34921 caaagtattt gttgagttgg agttggagga aggttgccac cccacacatg aagatatctg
    34981 tagaaatcag gtaggtcaac tgctcagctg aatagccaag ggctgtcgca atcatgatgg
    35041 gaaccaggat agatcctgag tacatggcta gtaagtgctg caagcccaga acggctgctt
    35101 gcgagtgttt ttcttgagtt tgcattagag atctgcctcc ttaaatacga cctgaccatt
    35161 ttcaaaacga tccaagcgag caagtgatag gacagggtag cctgcttttt caagcaaatc
    35221 acgaccatct tggaaggatt tctcaatcac gataccgata gcttggactg tggcaccggc
    35281 ctgttcgatg atttgaatca agcctttagc agcttggcca ttagcaagga aatcgtcgat
    35341 aatcaaaacc ttgtcctctg gtgagaggaa ttttccagcg atagaaacag tgctggtcac
    35401 ctgcttggta aaggagtaga cttgagcagt taagatgcct tcgttcatgg tgatgttctt
    35461 agcttttttg gcgaaaatca tgggaacgtt taaggcttca gctgtaaaaa cggctggggc
    35521 aatacccgac gcttcaatgg ttacgacctt ggtaatgcca gcagcagcaa atttttccga
    35581 aaaaacctta ccaatctctc gcatcaagct aaagtcaact tggtgggtta aaaaggaatc
    35641 taccttgagg atgttatcac ccaagatatg cccatccttg aggatgcgct cttctaataa
    35701 tttcataaga cctcctaaag tctaaaagtt aatttacttg ttgtttaaat gtttctatag
    35761 tgatcccttt tgctaatact atatatttga taaaactatt acgagcgaag cgagtcttat
    35821 caaatatttc ccgttgtagt ggtatcatag acaataatct tgttattgtc tatgacggga
    35881 tttttgagag taaaatagtt cggggaacta ttttagccta agcctagaaa tgaaagagct
    35941 aggggctcaa aaattaggga tgaaattccc tggattcctg aaattattca caggataatt
    36001 tcacctcccg tccgcactaa ttaagggaaa tattaaaaat attcaaaaaa gacctactta
    36061 atctctaagt aagtccccca aataggcatg gcaaaaacgg ccatatctca ctgctgactt
    36121 acttattgtt aggtgttccg gcaccttgta gaaacgtcgt gccaattcac gacataaaca
    36181 agtaaaacga tattcaattt taaataggtt tgagccaatg tttttatttt acactaaata
    36241 actttataaa tcaactattt tgttagtgtt ttggtttaaa aaacgaacaa acagaagaag
    36301 gagtgaacaa aaactgcatt gtaagctaac atttatacta aatgaaaatc aaagagcaaa
    36361 ctaggaagct atccacaacc tcaaatcact gttttgaggt tgtggataga attgacagag
    36421 tcagtatcat atacctacgg taaggcgacg ttgatgtggc ttgaagagat tttcgaagag
    36481 tattagaaga tttttccatc ataaaaggca tactatcaag tttttaaaca cctgacaata
    36541 tgcctttttc taactttaaa gacttttccc aatttttatt attctactcg ctaaatctta
    36601 aaaaatagcc atttggatcc aaaactgcaa atttatgagg atagatatag ggatcactga
    36661 cacgaaactt tcttttggtc aagggacgat aaataggata gtttgccttc atcactcttt
    36721 aatagagttt tgaaacatcc tttatgccaa aggagagatt gactccacga ccaaaggggt
    36781 aggtcagttc agctagttga tcctttgttc cctcctctaa cattagttga cactcttcaa
    36841 gagaaagaaa gagaaagttt tcttctggac gttggtattc aatcctaaaa cccagtaaac
    36901 cacagtagaa ggaccgagac tgttcgatat tcgatacaag caactcggga atgaccgcat
    36961 tgtagtccat atagaaaatc cttacaagtc aatttccaag acaatcggtg tatggtcttg
    37021 gcgagcacct gagtcaatca tatcagattt agtgaccttg tcagcgatac ggttacttgt
    37081 gagccagtag tcgattctcc agcctgtatt gttgatttta gaagttttgc tgcgttgtgc
    37141 ccaccaagtg tagcgttcag gaacatcgcc atgaacatgg cggaaggtgt ctgtaaatcc
    37201 agttgccaaa aggttggtaa atccagcacg ttcctcgtca gtaaatccag gtgaacggcg
    37261 gttgctagca ggatttgcaa ggtcgatttc attgtgggct acgttgtagt caccggtcgc
    37321 aaggactggt ttttctttgt ctagttcagc caaatactca gcatatttaa catcccagac
    37381 ttggcgttct tccaagcgtt tgagaccgtc accagcgttt ggagtgtaaa cttgggttac
    37441 gaaaaatgca tcaaattcta gagtgatgat acggccttcc aagtccatgg tagaaggggc
    37501 accgatttct gggaagctga tcgtaggcgt aagttctttc ttataaagga acatggttcc
    37561 agcatagcct ttacgggcag gctcttggga agagcgccac gtgttttcgt agcctgggaa
    37621 gagttcttct aaaatttcca cgtgtttctt tgtaggtcct ttggcagaaa gcttggtttc
    37681 ttggatagca atgatatcag cattttcagc gaccaaggtt tgtaggactt cttgggacaa
    37741 tttggcacga gctgagtcac tagttagggc agcgtttagg gaatcaatat tccatgagat
    37801 aagtttcata aagttacctt tttcattcag attatagatt ttattatacc aaaaaaagat
    37861 ctatttcccc aacgtatagt ttgaaaaatt actctctttc gtttataatt aagaatgatt
    37921 ttatgaaagg gagtgaaaat acatgaaatt ctactcttat gactatgtac tcagtcaaat
    37981 cggtcagcaa aatggtatta tggttggctt tgggattgtt ctattagctg tgacagtttt
    38041 tttgctttta aggcatacca tgataaaaag ggaaccgaat ttcgtgagtt ggtcatgatt
    38101 tcagctctgg ccttatttag ctctgctttt ggtcagcatc acgacttatc aaaacaatca
    38161 agtttctaac aataaatttc aaacttcact tcatttcatc gaggttgttt ccaaagattt
    38221 gggagtagac aagtcagaag tctatgttaa tacttccaca aacacagatg gcgcacttat
    38281 caaggtggga gaacgctatt atcgtgccct aaacggaagt gagccagaca agtacctgtt
    38341 agagaaagtc gaattgtata agacagacgc aattgaactg gtggatgtga acaaatgaca
    38401 cttaattata tcgaaatttt aatcaaactg gtcttgactc tcaaatagct caacaacaat
    38461 gttcactttg tgaaacgttt gattgatggt aagccaactc tccttatcaa aaatgggaat
    38521 attgacccat aagcctgtcg ttcagttggt ttgtctgcat cggatgtagc cctcaaactt
    38581 cgtagccaag ggattttcca gatgaagcaa gtcaaacgag ctgtgcaaga gcaaaatggg
    38641 caactcatcg ttgtgcaaat gggagatgaa aatcctaagt atccagttgt gactgacggt
    38701 gtgattcaag tagatgtctt ggaatcgatt ggtcgtagcg aagagtggtt gcttgataac
    38761 ctcagcaaac aagggcatga caatgtagcc aatatcttta ttgctgaata tgacaagggt
    38821 gctgttacag tcgtaactta tgaataagaa aaacctgggg tcttgtactc ttcgaaaatc
    38881 tcttcaaacc gcgtcaacgt cgccttgccg tatgtaggtt actgacttcg tcagttctat
    38941 ctacaacctc aaagcagtgc tttgagcagc ctgcggctag tttcctagtt tgctctttga
    39001 ttttcattga gtattggcct caggtttcca tttgcaatca gaaagggatt ttatgtccat
    39061 tattcaaaaa ctctggtggt ttttcaagtt agaaaaacgc cgttatctag tcgggattgt
    39121 ggccctggtc ttggtttccg tcctcaatct cattcctcct atggttatgg ggcgggtcat
    39181 tgatgccatc acatcggggc aattaaccca gcaggacctc cttcttagcc tattttactt
    39241 gctacttgca gcctttggta tgtactattt gcgctatgtg tggcgtatgt atatccttgg
    39301 gacctcttat tgcttgggac agatcatgcg gtctcgcttg tttaagcatt tcacaaaaat
    39361 gtcatcagcc ttttatcaaa cctatcggac gggtgatctg atggcacacg caaccaatga
    39421 tatcaatgcc ttgactcgtt tagcaggtgg cggtgtcatg tctgcggtgg atgcctctat
    39481 cacggctctg gtgactttgt tgaccatgct ctttagcatc tcatggcaga tgactcttgt
    39541 tgccattctc cccctacctt tcatggccta tgcgactagt cgcctaggga gaaagactca
    39601 taaggccttt ggcgaatccc aagctgcttt ttctgaactc aataacaagg tacaggagtc
    39661 cgtatcaggt atcaaagtga ccaagtcttt cggttatcag gcagacgagt tgaagtcttt
    39721 tcaggcagtc aatgaattaa ccttccaaaa gaacctgcaa accatgaaat atgatagtct
    39781 ctttgaccct atggttctcg tgtttgttgg ttcgtcctat gttttaacgc ttttggttgg
    39841 ctccttgatg gttcaggaag ggcagattac agttgggaat ctagtcacct ttatcagcta
    39901 tttggatatg ctggtctggc ctcttatggc catcggcttc ctctttaata ctactcagcg
    39961 agggaaggtt tcttaccagc ggattgaaaa tcttttgtct caggaatctc ctgtacaaga
    40021 ccctgagttt cctctggatg gtattgaaaa tgggcgtttg gagtatacca ttgacagctt
    40081 tgcttttgaa aatgaggaaa cactgacgga tattcacttt agtttggcaa aagggcaaac
    40141 cctgggcttg gttgggcaga caggctctgg gaaaacgtcc ttaatcaagc tcctcttgcg
    40201 tgaatacgat gtggataagg gtgccattta tctaaacggt cacgatattc gggactatcg
    40261 tctgacagac cttcgcagtc tcatgggcta tgttcctcag gaccagtttc tctttgcaac
    40321 ttcaatccta gacaatatcc gctttggcaa tcctaacttg cccctttcag cggtcgagga
    40381 agctactaag ctagcccgag tttaccaaga tattgtagac atgcctcaag gatttgatac
    40441 gctgattggt gaaaaaggag tcagtctttc tggtggtcaa aagcaacggt tggctatgag
    40501 tcgggctatg attttagacc ctgatatctt gattttggat gattccttat ccgccgtaga
    40561 tgccaagaca gagtatgcga ttatcgacaa cctcaaggag acgcgaaagg acaagacaac
    40621 cattatcact gcccatcgcc tcagtgctgt tgtccatgca gatttgattt tagtcctgca
    40681 aaatggtcaa attatcgaac gaggcaggca cgaagacttg ctagcgatgg atggctggta
    40741 tgcccaaacc taccagtctc agcagttaga aatgaaagga gaagaagatg cagaataaac
    40801 aagaacaatg ggctgtattg aagcgcttga tgtcttatct caagccttat ggactcctga
    40861 cctttttggc actcagtttt ctcctagcga cgacggtcat taaaagtgtc atacccctcg
    40921 tggcttccca ctttatcgac cagtatctca gcaatcttaa ccaactagcc gttaccgttt
    40981 tgctggtcta ctatggtctc tacatcctac aaactgtagt tcagtatgta ggcaatcttc
    41041 tctttgcgcg cgtgtcttac agtattgtta gggatattcg tcgagatgcc tttgccaata
    41101 tggagaaact gggcatgtct tactttgaca agacgccagc aggttctatc gtttctcgtt
    41161 tgaccaacga taccgagacg attagtgata tgttttctgg gattttatcc agctttatct
    41221 cagcagtttt tatctttctg acaacccttt ataccatgtt ggtgctggat tttcgtttga
    41281 cggctttagt cttgctcttt cttcctttga ttttcctttt ggtcaatctc tatcgaaaaa
    41341 agtcagtgaa aatcatcgag aaaaccagaa gtctcttgtc agatatcaat agtaagctgg
    41401 cagagaatat cgagggaatc aggattattc aggcctttaa tcaagagaag cgcctgcagg
    41461 cagaatttga tgaaatcaac caagagcact tggcctatgc caaccgttct gtagccttgg
    41521 atgccctctt tttgagacct gccatgagtt tgttgaaact tctaggttat gctgtcttga
    41581 tgacctattt tggctatcgt ggtctttcta tcgggataac ggccgggacc atgtatgctt
    41641 ttatccagta catcaaccgc ctctttgacc ctttgattga ggtgacgcaa aacttttcaa
    41701 cactgcaaac gtctatggtt tctgcaggcc gtgtctttgc cttaatcgat gagaggacct
    41761 atgagcccct tcaagaaaat gggcaggcta aagtccaaga aggcaatatc cgttttgaac
    41821 atgtgtgctt ctcatatgat ggcaaacatc cgattctgga tgatatttcc ttttcagtta
    41881 acaagggtga aaccattgcc tttgtaggtc atacaggttc agggaaatcg tctattatca
    41941 atgtcctcat gcgcttttat gaattccagt cagggagagt tctcttggat gatgtggata
    42001 tcagggattt cagtcaagaa gagctgagaa aaaacatcgg tttggtttta caggaaccct
    42061 tcctctatca tggaactatt aagtccaata tcgccatgta ccaagaaatc agtgatgagc
    42121 aggttcaggc tgcggcagcc tttgtggatg cagattcctt tattcaagaa cttcctcagg
    42181 ggtacgactc ccctgtttcc gagcgtggtt cgagcttctc tactgggcag cgccagcttc
    42241 ttgcctttgc tagaacagtc gccagccagc ctaaaatcct gattttggat gaagcgacag
    42301 ccaatattga ctctgaaaca gaaagtttgg ttcaagcttc tctggcgaag atgagacagg
    42361 gccgaacaac tattgctatc gctcaccgcc tttctactat tcaagacgcc aactgcatct
    42421 atgtcttgga taagggacgc attatcgaga gtggaaccca tgaggaactc ttgactctgg
    42481 gaggaaccta tcacaagatg tatagtttgc aggcaggggc catggcctat actctttgaa
    42541 aatctcttta aaccatgtca gctttatctg caatctcaaa gctgtacttt gattttcatt
    42601 gagtactaga aggaaatcct tcaaattaca gatttctttc accgcctttt ccattttgtg
    42661 gtataatgaa aaatgttgac aaatagtata ataaaaacaa aggagaacag catgctgaaa
    42721 tgggaagact tgcctgtgga aatgaaatca agcgaggttg agtcttacta ccagcttgtc
    42781 tctaaaagga agggttcgct gattttcaag cgttgcttgg actgggtttt ggccttggtc
    42841 ttactggttc taacttctcc catctttctc atcttgagca tttggatcaa gttggatagc
    42901 aaggggccag tgatttacaa gcaagagcgt gtgacccagt acaaccgtcg gttcaagatt
    42961 tggaagttcc gtaccatggt gacggatgcg gataaaaaag gaagtctggt gacttctgct
    43021 aacgatagcc gtattaccaa ggttggaaat ttcatccgac gtgtccgttt ggacgaactg
    43081 cctcagttgg tcaatgtcct taaaggtgag atgtcctttg tcggtacacg acctgaagtg
    43141 ccacgttata cagagcagta tagccctgaa atgatggcaa ccttgctctt gcaagcagga
    43201 attacctctc cagccagcat caactacaag gatgaggaca ccatcatcag tcaaatgacg
    43261 gagaaaggtc tgtcagttga tcaggcctat gtggagcatg ttcttcctga aaagatgcgc
    43321 tataacctcg cctatctccg agagtttagt ttctttgggg acatcaaaat catgtttcaa
    43381 accgtgtttg aggtactaaa ataaagtagt cataagaaaa tgagtacaga taaaaggagc
    43441 aaatcaatgc caaattacaa tattccattt tcaccgcctg atatcacaga agcagaaatt
    43501 gctgaagtag cggataccct gcgttctggt tggatcacaa caggtcctaa aacaaaagaa
    43561 ctggagcgcc gcttgtctct ttacacacag acacctaaga ctgtttgtct caactctgcg
    43621 acagccgctc tggagttgat tttacgcgtt ttggaagtgg gacctggtga tgaagtcatc
    43681 gttccagcca tgacctatac ggcttcatgt agtgtcatta cgcacgtggg agcaacccct
    43741 gtcatggtgg atatccaagc agatacgttt gagatggact atgacctgct tgagcaagct
    43801 atcactgaga aaactaaggt gattatccca gtagagctcg cagggattgt ttgcgattat
    43861 gaccgtttgt tccaagtcgt ggagaaaaaa cgtgacttct ttaccgcttc aagcaagtgg
    43921 caaaaggcct ttaaccgtat tgtcattgtc tctgatagtg cccacgcttt gggatctact
    43981 tataaaggac aaccttctgg ttctatcgct gattttactt ccttctcatt ccatgccgtt
    44041 aagaacttta caacggcaga aggtggaagt gcgacttgga aagccaatcc agtgattgat
    44101 gacgaagaga tgtacaagga attccaaatc ctttcccttc acgggcaaac taaggatgct
    44161 cttgccaaga tgcaactggg gtcatgggaa tacgatatcg ttacaccagc ctataagtgc
    44221 aacatgaccg atatcatggc ttcacttggt ttggtacaat tggaccgcta tccaagtttg
    44281 ttgcaacgcc gtaaggacat tgtggaccgc tatgatagtg gttttgcagg ttctcgcatc
    44341 catcctttgg cacacaagac tgaaactgtc gaatcttcac gccacctcta catcacccgt
    44401 gtagaaggag caagcctaga agaacgcaac ctcatcatcc aagaattggc taaagcagga
    44461 attgcaagta atgttcacta caaaccgctt cctctcttga cagcctataa gaatcttgga
    44521 tttgatatga cgaactatcc taaggcctat gccttctttg agaatgaaat taccctccct
    44581 cttcatacta aattaagcga tgaagaagta gactatatca ttgagacttt caaaacagtt
    44641 tctgaaaaag tgctaacttt atcaaaaaaa tgacaaacta cagtcaagcg aaagtgatcc
    44701 tgtccctaaa aagtctaatt gagtgtaaaa actgttgttt tcaattgata atagtttaca
    44761 cctgtagttg aggcctcttt ctcctcagag agagaatttt tataggattt tcctttcttg
    44821 tgggagtccc gtggtttgaa ataagatgtg agcaatttgg tgtagcattt agaatcctta
    44881 ctagacatca tttagaaaat ctagtgtctt gttctagttt tcaattcacc ctattttttg
    44941 aaagacgtga gtttccatga gtgagattgt ggaaactcgc gtcttttttt gttttcagaa
    45001 tattgttcaa agttttgtgc ctgtctttca tgttctagtc attcttttgc atgatagaat
    45061 ttatagcata ttgatattat aataatacaa atattctata cgtttagtga tgcttgctat
    45121 acatcattag atctcccgcg agacaatcta taaaacactt gtctacgatt acctatatgc
    45181 cctattccag tattttagaa gcactgcatc tatttttatc gaggttaaat ctagctttta
    45241 tagaaggtct atttaagaaa tatagtgttt tagtttcaat ccgccatatg agcgatattc
    45301 aggtaaatat ccctggcgaa tgcttgtatg acaaggtatt tgttctttca tttataattt
    45361 acaacatatc aacaaattta aatatagtaa atgggatatt ttatattcaa gctaagaaag
    45421 atagcatcac ttttgaatgg aaggctaaag agcaaactag gaagttggcc atagatagct
    45481 caaaaccctg ctttgaggtt gtagatatag taaaatgaaa caagaatagg acaaattgat
    45541 cgggacagtt aaatcgattt ctaacaatgt tttagaagta gaggtgtact attatagttt
    45601 cagtctacta tagaactgac caagtcagta acctagactt aggtcaaggc ggcactgacc
    45661 tagtttgaag agatttccga agagtataaa ttttaatatt ttcttgtgtt attccttgac
    45721 aattcaattt ggaaaatata tgataaagat aatgacagcg gtgtcattct atctatttta
    45781 agaaaagtaa taatcaattg ttaaaaatag taaaaaattg gaggttctga tgaaatattt
    45841 tgttcctaat gaggtattca gtattcgtaa attaaaggtg gggacttgct cggtactatt
    45901 ggcaatttca attttgggaa gccaaggtat tttatcggat gaagttgtta ctagttcttc
    45961 accgatggct acaaaagagt cttctaatgc tattactaat gatttagata attcaccaac
    46021 tgttaatcag aatcgttctg ctgaaatgat tgcctctaat tcaaccacta atggtttaga
    46081 taattcgtta agtgttaata gtatcagctc taatggtact attcgttcca attcacaatt
    46141 agacaacaga acagttgaat ctacagtaac atctactaat gaaaataaga gttataagga
    46201 agatgttata agtgacagaa ttatcaaaaa agaatttgaa gatactgctt taagtgtaaa
    46261 agattatggt gcggtaggtg atgggattca tgatgatcga caagcaattc aagatgcaat
    46321 agatgctgca gctcaagggc taggtggagg aaatgtatat tttcctgaag gaacttattt
    46381 agtaaaagaa attgtttttt taaaaagtca tacacactta gaattgaatg agaaagctac
    46441 aattctaaat ggtataaata ttaagaatca cccttccatt gtttttatga caggtttatt
    46501 tacggatgat ggtgcgcaag tagaatgggg cccaacagaa gatattagtt attctggtgg
    46561 tacgattgat atgaacggtg ctttgaatga agaaggaact aaagcaaaaa atctaccact
    46621 tataaattct tcaggtgcat ttgctattgg gaattcaaat aacgtaacta taaaaaatgt
    46681 aacattcaag gatagttatc aagggcatgc tattcaaatt gcaggttcga aaaatgtatt
    46741 agttgataat tctcgttttc ttgggcaagc cttacccaaa acgatgaagg atgggcaaat
    46801 cataagtaag gagagcattc agattgaacc attaactaga aaaggttttc cttatgcctt
    46861 gaatgatgat gggaaaaaat ctgaaaatgt gactattcaa aattcctatt ttggcaaaag
    46921 tgataaatct ggggaattag taacagcaat tggcacacac tatcaaacat tgtcgacaca
    46981 gaacccctct aatattaaaa ttttaaataa tcattttgat aacatgatgt atgcaggtgt
    47041 acgttttaca ggattcactg atgtattaat caaaggaaat cgctttgata agaaagttaa
    47101 aggagagagt gtacattatc gagaaagcgg agcagcttta gtaaatgctt atagctataa
    47161 aaacactaaa gacctattag atttaaataa acaggtggtt atcgccgaaa atatatttaa
    47221 tattgccgat cctaaaacaa aagcgatacg agttgcaaaa gatagtgcag aatatttagg
    47281 aaaagtatca gatattactg taacaaaaaa tgtaattaat aataattcta aggaaacaga
    47341 acaaccaaat attgaattat tacgagttag tgataattta gtagtgtcag agaatagtat
    47401 attcggtggt aaagaaggaa ttgttattga ggatttaaag ggtaaaataa ccgttttaaa
    47461 taaccaattt tataatttat ccggtaagta tatatcattc atcaaatcta atgcaaacgg
    47521 gaaagaacct gttatacgtg atagcgatgg taatttcaat attgtaacgg agaatgggct
    47581 ttacaaaatt gtaacaaata atttaagtga taaaaacgaa aaagaaaaaa acaaagagga
    47641 aaaacaatct aattcaaata atgtaattga tagtaaccag aagaacggag agtttaactc
    47701 aagtaaagat aatagacaaa tgaatgacaa gatcgacaat aaacaagata ataagacaga
    47761 agaagtaaac tataaaatag ttggagatgg cagagaaact gaaaatcata ttaataaatc
    47821 taaagaaata gtagatgtaa aacaaaaatt accaaagact ggttcgaaca agattatgga
    47881 actattctta acagtgacag gaattggttt acttttgaca ctaaaagggt tgaagtatta
    47941 tggtaaagat aaataaaatt tgttcgatac aaggaagttc cgtagaaaat gaggatattg
    48001 taggttcaca aaatcagtat ttttggatta ttggtggagc tacagattta tataattcta
    48061 aagaggagat aggttattca gtctcagaag ttgtacatat tttatcagaa agtttgtcgg
    48121 ttaattgtaa agaatcaaaa actcttaaac aaatatttga aactgcttta ctcgaggtta
    48181 aagatgaaat cggtttaaac tcatatgaat taacagagta taataaaatg aaataa
//
LOCUS       DAVMCG010000011        48136 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVMCG010000011 DAVMCG010000000
VERSION     DAVMCG010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.011"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            71..1060
                     /gene="manX"
                     /locus_tag="VYP66_000778"
     CDS             71..1060
                     /gene="manX"
                     /locus_tag="VYP66_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1850366.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            1088..1891
                     /locus_tag="VYP66_000779"
     CDS             1088..1891
                     /locus_tag="VYP66_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1850367.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            1915..2826
                     /locus_tag="VYP66_000780"
     CDS             1915..2826
                     /locus_tag="VYP66_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1850368.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(2882..4216)
                     /gene="pepC"
                     /locus_tag="VYP66_000781"
     CDS             complement(2882..4216)
                     /gene="pepC"
                     /locus_tag="VYP66_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1850369.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(4433..5155)
                     /locus_tag="VYP66_000782"
     CDS             complement(4433..5155)
                     /locus_tag="VYP66_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1850370.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            complement(5468..5698)
                     /locus_tag="VYP66_000783"
     CDS             complement(5468..5698)
                     /locus_tag="VYP66_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1850371.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            complement(5708..6949)
                     /locus_tag="VYP66_000784"
     CDS             complement(5708..6949)
                     /locus_tag="VYP66_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1850372.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMESLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            complement(7144..7422)
                     /locus_tag="VYP66_000785"
     CDS             complement(7144..7422)
                     /locus_tag="VYP66_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1850373.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPTRY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            complement(7415..7678)
                     /locus_tag="VYP66_000786"
                     /pseudo
     CDS             complement(7415..7678)
                     /locus_tag="VYP66_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
     gene            complement(7780..12171)
                     /locus_tag="VYP66_000787"
     CDS             complement(7780..12171)
                     /locus_tag="VYP66_000787"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1850374.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFNVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLDRLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEVYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEAIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            complement(12275..14356)
                     /gene="fusA"
                     /locus_tag="VYP66_000788"
     CDS             complement(12275..14356)
                     /gene="fusA"
                     /locus_tag="VYP66_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1850375.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            complement(14781..15251)
                     /gene="rpsG"
                     /locus_tag="VYP66_000789"
     CDS             complement(14781..15251)
                     /gene="rpsG"
                     /locus_tag="VYP66_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1850376.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            complement(15271..15684)
                     /gene="rpsL"
                     /locus_tag="VYP66_000790"
     CDS             complement(15271..15684)
                     /gene="rpsL"
                     /locus_tag="VYP66_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1850377.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16101..19943
                     /gene="spuA"
                     /locus_tag="VYP66_000791"
     CDS             16101..19943
                     /gene="spuA"
                     /locus_tag="VYP66_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1850378.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            complement(20043..21092)
                     /locus_tag="VYP66_000792"
     CDS             complement(20043..21092)
                     /locus_tag="VYP66_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1850379.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            21149..21286
                     /locus_tag="VYP66_000793"
     CDS             21149..21286
                     /locus_tag="VYP66_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850380.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEVVDRTDEISNHTYGKATLTWFEEI
                     F"
     gene            complement(21363..23171)
                     /gene="glmS"
                     /locus_tag="VYP66_000794"
     CDS             complement(21363..23171)
                     /gene="glmS"
                     /locus_tag="VYP66_000794"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1850381.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(23363..24742)
                     /gene="bglA"
                     /locus_tag="VYP66_000795"
     CDS             complement(23363..24742)
                     /gene="bglA"
                     /locus_tag="VYP66_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1850382.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            complement(24842..26695)
                     /locus_tag="VYP66_000796"
     CDS             complement(24842..26695)
                     /locus_tag="VYP66_000796"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1850383.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            complement(26708..27967)
                     /gene="rseP"
                     /locus_tag="VYP66_000797"
     CDS             complement(26708..27967)
                     /gene="rseP"
                     /locus_tag="VYP66_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1850384.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            complement(27989..28792)
                     /locus_tag="VYP66_000798"
     CDS             complement(27989..28792)
                     /locus_tag="VYP66_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1850385.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIVAMLAMHE
                     LLKMRGLATMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            complement(28801..29559)
                     /locus_tag="VYP66_000799"
     CDS             complement(28801..29559)
                     /locus_tag="VYP66_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1850386.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            complement(29790..30362)
                     /locus_tag="VYP66_000800"
     CDS             complement(29790..30362)
                     /locus_tag="VYP66_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1850387.1"
                     /translation="MNTVKNKQEILEAFRESPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEELDFELYVPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            complement(30343..31314)
                     /gene="ruvB"
                     /locus_tag="VYP66_000801"
     CDS             complement(30343..31314)
                     /gene="ruvB"
                     /locus_tag="VYP66_000801"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1850388.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNDLEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDVITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            31476..31568
                     /locus_tag="VYP66_000802"
     CDS             31476..31568
                     /locus_tag="VYP66_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1850389.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            complement(32320..33577)
                     /gene="ltrA"
                     /locus_tag="VYP66_000803"
                     /pseudo
     CDS             complement(32320..33577)
                     /gene="ltrA"
                     /locus_tag="VYP66_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(34317..34733)
                     /locus_tag="VYP66_000804"
     CDS             complement(34317..34733)
                     /locus_tag="VYP66_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850390.1"
                     /translation="MITIKKQEIVKLEDVLHLYQDVGWTNYTHQTEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPSYQRQGIGSSLMKEALGNFKEAYQVQ
                     LATEETEKNVGFYRSMGFEILSTYDCTGMIWINREK"
     gene            complement(34745..35440)
                     /locus_tag="VYP66_000805"
     CDS             complement(34745..35440)
                     /locus_tag="VYP66_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850391.1"
                     /translation="MPVNEYGQMIGESMEAYTPGELPSFDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQESVADMEELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLACYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLGFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKARLEIWLRPENF
                     DKNGRQHKSLREL"
     gene            complement(35634..38135)
                     /locus_tag="VYP66_000806"
     CDS             complement(35634..38135)
                     /locus_tag="VYP66_000806"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1850392.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWPESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVAEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLNASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEISLADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            complement(38590..39678)
                     /locus_tag="VYP66_000807"
     CDS             complement(38590..39678)
                     /locus_tag="VYP66_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1850393.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(39696..40364)
                     /locus_tag="VYP66_000808"
     CDS             complement(39696..40364)
                     /locus_tag="VYP66_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1850394.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            complement(40383..42821)
                     /locus_tag="VYP66_000809"
     CDS             complement(40383..42821)
                     /locus_tag="VYP66_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1850395.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(42972..44270)
                     /locus_tag="VYP66_000810"
     CDS             complement(42972..44270)
                     /locus_tag="VYP66_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1850396.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(44287..44595)
                     /locus_tag="VYP66_000811"
     CDS             complement(44287..44595)
                     /locus_tag="VYP66_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1850397.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(44641..44961)
                     /locus_tag="VYP66_000812"
     CDS             complement(44641..44961)
                     /locus_tag="VYP66_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1850398.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(45156..46136)
                     /locus_tag="VYP66_000813"
     CDS             complement(45156..46136)
                     /locus_tag="VYP66_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1850399.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(46149..46895)
                     /locus_tag="VYP66_000814"
     CDS             complement(46149..46895)
                     /locus_tag="VYP66_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1850400.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            47017..47793
                     /locus_tag="VYP66_000815"
     CDS             47017..47793
                     /locus_tag="VYP66_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1850401.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            47868..48065
                     /locus_tag="VYP66_000816"
     CDS             47868..48065
                     /locus_tag="VYP66_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1850402.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
BASE COUNT        14226 a        10931 c         8702 g        14277 t
ORIGIN      
        1 cggtttatac ttaaacagtc ttaaagtttt cttaaatgaa aactaaaaca aaaaaggagg
       61 aatgacaata atgagtatcg gaatcattat tgcgagccac ggcgaatttg ctgcgggtat
      121 tcatcagtca ggatctatga tctttggtga acaagaaaag gttcaagttg tgacctttat
      181 gccaaatgaa ggtcctgatg atctatacgc taagtttaat aacgctgttg ctgcatttga
      241 cgcagaagat gaggttctag ttttggctga cctttggagt ggttctccat ttaaccaagc
      301 tagtcgcgtg atgggagaaa atcctgagcg taagtttgcc atcatcacag gacttaactt
      361 accgatgttg attcaagcct acacagagcg cctcatggac gctgctgcag gtgtagaaaa
      421 agtcgctgct aatatcatta aagaagccaa agatggcatc aaagctcttc cagaagagct
      481 aaatccagtt gaagaagttg caagcgctgc agctgctcca gttgcccaaa ctgctatccc
      541 agaaggaact gttatcggag acggtaaatt gaaaatcaat cttgcccgtc ttgacacacg
      601 tctacttcac ggtcaggttg caactgcttg gactccagat tcaaaagcaa atcgtatcat
      661 cgttgcttca gataacgtgg ctaaagacga ccttcgtaaa gaattgatta aacaagcagc
      721 tccaggtaat gtcaaggcta acgtggttcc aattcaaaaa ctgattgaga tttcaaaaga
      781 cccacgtttt ggagaaacac atgcccttat cttgtttgaa acacctcaag atgcccttcg
      841 tgccatcgaa ggcggcgtgc caatcaagac tcttaacgtt ggttctatgg ctcactcaac
      901 aggtaaaaca ttggtcaata ccgttttgtc tatggacaaa gaagatgttg ctacatttga
      961 aaaaatgcgt gacttgggtg ttgaatttga tgtccgtaaa gtaccaaatg attctaaaaa
     1021 agatttgttt gacttgatta acaaagccaa tgtcaaataa gccattattt atgaaaggat
     1081 tttaaacatg tctattattt ctatggtttt agtagtcgtt gtagccttct ttgcaggtct
     1141 tgaaggcatc ctcgaccagt tccaatttca ccaaccactt gtagcctgta cccttattgg
     1201 gcttgtaaca ggtcacttgg aagcagggat tatcctcggt ggatcgcttc aaatgattgc
     1261 ccttggttgg tcaaatatcg gtgctgctat cgctcctgat gctgcacttg cttctgtcgc
     1321 tgctgccatt atcatggttc ttggtggtga ctttaccaag actggtatcg gtgttgccca
     1381 agcggttgct atccctcttg ccgtagctgg acttttcttg acaatgattg ttcgtacaat
     1441 ttcagttggt ttggttcata ctgcagatgc tgccgctaaa aaaggtgact tcggcgctgt
     1501 ggagcgtgcg catttcattg cgctactctt ccaaggactt cgtatcgcgc ttcctgcagc
     1561 tcttctcctt atggtaccaa ctgaaactgt acaaagtatc cttagtgcca tgccagactg
     1621 gctcaaagat ggtatggcta tcggtggtgg tatggtcgtt gccgttggtt acgccatggt
     1681 tatcaacatg atggcaactc gtgaagtatg gccattcttc gctcttggtt tcgttctcgc
     1741 tgctgtgtca gatattactc taatcggatt cggtgctatc ggtgttgcta tcgctcttat
     1801 ctaccttcac ctttctaaaa ctggtggaaa tggtggcgga ggagccgcaa cttctaacga
     1861 cccaatcggc gatatcctag aagactacta agataagaaa ggactgaaaa catcatgact
     1921 gaaaaacttc aattaactaa atcagatcgt aaaaaagttt ggtggcgttc aaccttctta
     1981 caagggtctt ggaactttga acggatgcaa aacttgggct gggcttatac actcattcca
     2041 gctatcaaaa aactctatac taaaaaagaa gatcaaatcg ctgctcttga gcgtcacctt
     2101 gagttcttca acactcatcc atacgtagct gctccagtca tgggggttac tcttgcgctt
     2161 gaagaagaac gtgctaacgg tgtggaaatc gatgacgctg ctatccaagg ggttaaaatc
     2221 ggtatgatgg gacctcttgc tggtatcggt gacccagtat tctggtttac agtacgccca
     2281 atccttggat ctctcggtgc ttcacttgcc cttactggca atatcttggg gccactcctc
     2341 ttctttgttg catggaactt gattcgtatg tcattcttgt ggtatgttca agagattgga
     2401 tacaaggctg gatcagaaat cactaaagat atgtctggtg gtatccttca agatatcact
     2461 aaaggagctt ctatccttgg gatgttcatt cttgctgtcc ttgttcaacg ttgggtaaat
     2521 attaaatttg ctttcgatgt ttctaaagtt caactagatg aaaaggctta tatccattgg
     2581 gataaattgc cagaagggtc taaaggtatc caagaagcat tcgcacaagt aggacaagga
     2641 ttgtctcaaa ctcctgaaaa agttactact ttccaacaaa acttggatat gttgattcct
     2701 ggattatcag gactactcct tactttactt tgcatgtact tacttaagaa aaaagtatct
     2761 ccaatcacta ttatccttgc cctcttcgca gtgggtattg tggcacatgt tcttcacatc
     2821 atgtaatcaa gcaactaaaa aggaaccagg ttctaaaatc tgattccttt tttctatgct
     2881 tttattcagc caaggctccc attggatccc atggtgcaag tacgattggt tctgctccat
     2941 aggcagcttg ttcttctgct gtcagcaatt ccttacgaac aacgatttgg tatgtgtatt
     3001 cgtccatcca agcgtctgag gcaacaaagt aaccatctgt accgaccttg tctccccatg
     3061 agttttcaac cttccacttg gttgatttac cattttcgtc caagtcaaca cctgtcaaga
     3121 ccatggcgtg ggtcatcaag ctttcgctat agtccaaacg tccagccttg tcttgagtaa
     3181 gtttaatgtc catgcttgat tcaaagtcat aaacatctgt cgcaaggatg ccagccttac
     3241 ggttgctgag ctggccgaca tcagaaccaa accaaacagt ctcacctgct tgcatttggg
     3301 caatcgccaa ttctttcaag cgctccattg gaacgttgat gtagcgaact gcacggctac
     3361 caaccacatt ccccaacatc tcaactgtgt aagattttcc gtaaggttta tcagcagttg
     3421 gagcattgat aacagaaacg tagtcttcta aaggaagatt gacatatttc ttgtaaaact
     3481 cttgtggtgt gattcctttt tcacttttat agttgttatc tttatcgcga taagcaaagt
     3541 caaacttgcg tggtggaagt cctaatgaca tagcaagaaa gttaaagatt tcttgcaaga
     3601 ggtcttcttt cttagcttga acagtcgctt gatctgcacc agaaacaagc aaatcacgca
     3661 agatttgagc atcttgacga agcaatttat taaggatcgc atttagctca cgactgctgc
     3721 tagatgaaac agactcagga taaactgact taggcacgac accgtatttt tcaaagaggg
     3781 aaacgaccat atcccattga ccgccatctt gttgaggtgt ttggagtaag aagctaacct
     3841 tgcggctagt caattcttgg tctgaagtcg caatgacttg ctccaagaac cagtttgatt
     3901 tctcatactt atcccagaag aaagtgtggg cttgtgacaa ctcaaagttc tccaatttgt
     3961 attgcgagat gagtttgtgg cggaaggtgt tgagagccgc aaacatccag caacgaccag
     4021 acgctttctg gttagtgacc ttgtccttgg ttaaatccaa tgagaaaaca ggtgtgttgt
     4081 ctacatggct ttggcgacat tccagagctg caaaaattcc gttgtggctg gcagcatttt
     4141 caatcgcttg gtattttaca tttgcttcat agttggcaaa tagtttatca gtaaatgatt
     4201 cttgaatcgc gttcatagat tcctcctttt attctacagt ctattataac tcttttcaca
     4261 aaggaagcaa ctaaaaaaca taaaaggcga ggacattgtc cctcaccttt ttcgaattta
     4321 tactcttcga aaatctcttc aaaccacgtc aacgtcgcct tgccgtactc aagtacagcc
     4381 tgcggctagt ttcctagttt gctctttgat tttcattgag tattaaacta aattaaataa
     4441 tattagcgcg gagaatttct aattcttcct tggtcaagcg acgccattcc cctcgttcca
     4501 ggttctcatc taatactaaa gttcccatag tcaatcgttg caagtccacc acttccttgc
     4561 cacagtagcc caccatacgc ttgatctgat gaaacttccc ttctgcaatg gtcacacgga
     4621 tttggctctg attcttttct gcatctgtgg aaagaatctc cagtctagcg ggctgacagg
     4681 taaagtcttt gagcggaatg cccttgataa atgtctccac atcttcttgg gtcataattc
     4741 ccttgacctg agcctgataa gtcttgtcca catgacgctt gggcgaaaga agaacatgag
     4801 ccagctgacc attattggtc aagagcaaaa gaccatgcgt gtcaatatcc aagcgtccta
     4861 ctggaaaaac ttccttactc cgcgccaagt catccaacaa gtccagaacg gttctgtgct
     4921 tgggatcctc agtcgctgag ataactcctt tgggcttgtt catcatgtag tagacaaact
     4981 cttcatactc caacacttgc ccatcaaagc gaatctcatc tattttttca tcaatctgca
     5041 atttagctga tttttctttt ttaccattta cagtcacgcg cccagccttg agcaagtttt
     5101 tgacctcagt ccgacttccc accgcacagg caactaaaaa tttatctaat ctcatagaac
     5161 tattatatca tatcaaaagg aggctagtac aatgaccaac ctccttttcg tttcatactc
     5221 ttcaaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtt actgacttcg
     5281 tcagttctat ctgcaacctc aaaacagtgt ttttagctga cttcgtcagt tctatctgca
     5341 acctcaaaac agtgttttta gctgacttcg tcagttctat ctgcaacctc aaagcagtgc
     5401 tttgagcaac ctgcggctag tttcctagtt tgctctttga ttttcattga gtatcagatt
     5461 taggaaatta acttcctcgt ctccaaaaaa tagctaaaac aatcatggct cctaaaatcg
     5521 ctgggataat agctgttcct gataaaactg gcccccaagt tccaaagagc aagtgaccta
     5581 gaaaggctcc gatccaaccg agaaacattt ttccaaaaca tcccattcgc tctccacgat
     5641 tggtcatagc acctgctaaa aatcccacta ggagaccaac gaacatactt cctaacatat
     5701 tatctcctta atttgcccaa ttcccattac ggaaaagagg tacccgcgtt ccatcctcac
     5761 gaataccatc gatatccatt tggttagaac caatcataaa gtctacgtga acatctgaac
     5821 ggttaagccc tgcagcttca agctcctctt cgctcatctc cgctccatca acaacgctag
     5881 tcgcataggc tgcaccgata gccaagtggt ttgacgcatt ttcatcgaaa agggtgttaa
     5941 aaaaggtaat gcctgactga gaaattggac ttggatctgg taccaaggca cattcaccca
     6001 aggcacgcgc acccgcattt ttaaagacaa ggtctttcat aacctgatca cccttctcag
     6061 cagtgatatc tacgatttgt ccatccttaa aggtcacctt aatgccttca atgatatttc
     6121 cgttgtagct aagcggtttt gtagaagtga cataaccatc tgcacgacgg aagtcaggcg
     6181 ctgtgaagac ctcttctgtc ggcatatttg gcaagaatcc ttcgccctgt gcattgacag
     6241 caccagctga ttcccaaacg tggttctttg gcaaaccaag tgttaaatct gttcctggcg
     6301 ctgtgtagtg aagggctgaa aattgctcct tattaagcat atcggccttg ctcttcaaga
     6361 tagctgcatg ctcttcccag gccttaacag gatctgcttc gtagacacgg caagttttga
     6421 aaatttggtc ccaaaggaaa tcaactgctt cttcgtcgct cgcagcattt gggaagactt
     6481 tcttagccca ctcaagtcct gctgcagctg ctacagtcca gctaaccttg ttagattgag
     6541 ttgcgatacg cataggcttc atggcaagtc ccatagcttt agcagaagct gaaagcttgt
     6601 cagcgtccac tccgttcaag gcacctggat cagatgaacg aactccaaga cggctagcct
     6661 tattctccaa gagatagttc atctcagcaa tcttgtattc tggcacattg tccaaactct
     6721 ccatcggggc atggagaaat ttctcacggt taatcacatc atctgtccac tgaacgatga
     6781 cctcatgcgc acccaaggca taagcttctt tcacgattag atgtgccaat tcacgttgct
     6841 ccacatcaat agagagagcc aaagtgtgac caggttgcac gttaattccg ttcgcaacca
     6901 acaatttcgc atatttttct agattttctt taaaatttgg taaaaccatg taattttctc
     6961 ttttctattt ttatttttct ttcaaagcag agaataatca cgctaaagca atagcacctg
     7021 acaagagtgc tgttgataga agaattgtac gatcagcaag ttctaattga tattcaaata
     7081 ccttcttagc cggcttatct tccgcaaata ttcttagttt catgagaacc cccttaaaat
     7141 agattaaaat aaatcactgt gactgcctgt cctcagcaaa tttaaaatca attccgactt
     7201 gtctacttta taaaccaaaa gccaatctgg ctgggtatgg cattcacgaa ctccttgaaa
     7261 atgcttggat gccgtcaatg aatgatcacg atatctggta ggatgttctt tttcttgaac
     7321 cagaaaattc aaaacttctt ctaataattc tgccttcaaa ccacgcttca tagccaactt
     7381 aaaatctttt ttaaactgtt tatgatagcg aatcttaagc acgtaagtcc tccatcaaat
     7441 ctgagactga ttcaaaagac tggctcatat tacgatttta gtctaaatcc gttaacgctt
     7501 ggagcaactt ccgattttcg tctagtctaa catcaaaagg taatccctga tattgaattg
     7561 cctgacgaag gaaaatatta atagctgttg tcatatccat tcccagatta ctaaacacct
     7621 gttgggcctg ctccttaacc tcactatcca gacggatgct tatactcatc tttgacatac
     7681 tctcaccctc tttccataga ctattttaac aaaaaagaaa gctaatgtaa atctattgga
     7741 tatacgttag cctcttttaa tagattatta agcaattttt taaaacaact catcaaacaa
     7801 actcaactgg ttatcctctg gcatatttcc aagaataccc atctcatcca tcttttcaac
     7861 caaggttgat gagagtccac cacgcttgcg tagttctgtt ttagagagga attctccctc
     7921 ttcacgcgcc cgcaccagtt gcttggcaac gttctctccc agaccatcca ttgctacaaa
     7981 tggtgggata agggtatccc cgtcgatgag gaactctgtc gcctgactac agtagagatc
     8041 taatttacca aacttgaaac ctcgttccca catctcattg acaatctcaa gagttgtata
     8101 gagatcgatt tccacattag aggcttcatt gttcttccgt ttttcagaga tttcttccat
     8161 tctgcgcttg atggcctcca agcccgcacc catggtcttg atatcaaaag ccttagcacg
     8221 aatggagaag taagcacagt agtaataaat aggatggtga accttgaagt aagctacacg
     8281 caaggccatc ataacgtagg ctgccgcatg ggccttaggg aacatgtact taattttccc
     8341 acaggattcg atataccact ctggcacctt attagccttc atggcttcga tatagccatt
     8401 tctctcctct tctgaaatct ttagccacaa acccttacgt acccgttcca taatggtaaa
     8461 ggccatctta ggttccagac ccgcatgcat gaggtaaacc atgatgtcgt cccgacaacc
     8521 gataacagtc gataggtccg ctattccttg cttaatcaga tcctgagcat tccccaacca
     8581 aacgtcagta ccgtgggaca gaccagacag ctgaagcaat tccgcaaagg ttgtcggatg
     8641 ggtttcgtct accattccac gtacgaaatt tgttccaaac tctggaatcc ccaacatacc
     8701 cgtaggcgtt ccaatttgtt caggtgttac ccctagcaca tcagtcccag aaaagagtgc
     8761 catcacgcct tcgtcatcca taggaatttt attagggtca ataccagaca aatcctgaag
     8821 ttttcgaatc atggtcggat catcatgtcc cagtacatcg agtttgagga cgttctcatc
     8881 gatatcgtgg aagttaaagt gagtggtctg ccattcagcc gtgacatcat ctgctggata
     8941 ctggacaggc gtaaaatcgt agacatccat gtagttcgga ataacaacga ttccccccgg
     9001 gtgttggcct gttgtccgct tgacacccgc cgctccttga gcgaggcgtt ctacttctgc
     9061 atcacgataa aacttgccat aatctcgctc gtaacccttg acaaatccat aggcagtctt
     9121 ggcagctact gtaccaaccg ttcccgcacg gaaggcatat tcttcaccaa agatatcacg
     9181 cacatccaag tgggcgctag gctgatcttc tcccgagaag ttcaagtcaa tatcaggaac
     9241 cttatcccca tcaaaaccaa ggaaggtctc aaacggaata tcctgtccgt ttttactgag
     9301 tttgtgacca cagtttggac agtccttatg gggcatatca aatcctgaac cgtacgaacc
     9361 atctgtgata aactcactgt actgacactg accacagaca tagtgaggag agagaggatt
     9421 gacctccgta atcccaatca tggtcgcaac gaaactagat ccgacagacc cacgagaacc
     9481 aaccaaataa ccccgttcat tagaacgttg caccagcatc tgcgatgcca aataaatcac
     9541 agcaaatcca ttccccagta tggatgttaa ttctttttca atccgcaaat caacaatatc
     9601 tggcagcgga ttcccataaa tctcaaaagc tttcttatag gtcaactcag caactgtttc
     9661 ttcagccttg tcgatgaaag gcgtatacaa gtcaccctta acgacttcaa cgggttcaaa
     9721 tatttctgcc aaggcattgg tgttttcaat aaccagttta cgagccagtt cctctcccaa
     9781 aaaggcaaat tcatccaaca tctcattagt cgttcgaaaa tgagcctttg gaagtggcgc
     9841 tggttgggca tgttcaccat gaccgatagt tcggttaatc atcgcaccct gtcccaaact
     9901 acggacgata atttcacgat aaacctcttc ttccggttcg atatagtgaa catttcccgt
     9961 agccagaaca ggcttgccaa ggcgatctcc aacctctatc aaactcttga taatggtctg
    10021 gagttcctcc atatccttga cctgctcttt ggcaatcaag ggcgcataga tagccggtgg
    10081 catgacctcg ataaagtcat aatacttggc cacctcaacc gccgcatcca caccttgaga
    10141 aacgaccacg tcaaaaactt caccctctga acaggctgaa cctaaaatca agccctctcg
    10201 atgggcatct agaaccgttc tcggaatccg tggcactcct tcaaaatact tggtattaga
    10261 caaggaaacc agcttaaaga tattttttag acctacctga ttcttgacat agatggtcgc
    10321 atgcttgatc cgagcttttt tgtaagaatc tggactgatt agatcaatgt tgagtctatc
    10381 taaatcggtc acaccatgtt tttctgctac ctctttgata aagatgaaaa gcagacgacc
    10441 agtcgcttcc gcatcgtagt tggccatgtg gtgatgttcc aaggccacac caaaacgctt
    10501 ggtcaaaggc cccaaaccat ggcgtttata ctcaggatag aggtttctag caaactccag
    10561 cgtatcaata actggctgac taatctttgg aagatcatga cgctcataat tagcattcat
    10621 aaagccaacg tcaaaggtag cattgtgggc aactaggacc gtatccttgc aaaattcttg
    10681 gaattcttgc aaaacttgtt ctagtggttt ggcatttttg acatgatcat ctgtaattcc
    10741 agttaactct gtagtaaaag ctgacaaggg atgcccagga ttgataaatt catcaaattc
    10801 agcaataaca ttccccttgt acatcttaga ggccgcaacc tgaatcaagt cattatagat
    10861 agctgaaagt cccgtcgttt ccacgtcaaa gaccacgtag gttgcttctg acaagtccat
    10921 ctccacttcg ttatagacga tagggacacg gtcctccacg atattggctt ccattccata
    10981 gatcagctgg attcccgctt tcttagccgc cttatagcca tgtggaaagg actggacatt
    11041 cccatggtcc gtgatagcaa ccgccttgtg tccccactta gcagctgttg caacaatctc
    11101 ttcgacctct ggcaaagcat ccatagtcga catgttagta tgagcatgaa actcaacccg
    11161 acgctcacct tctggcatca aatccttccg ctcatagtga acaacttcct gcagatcctg
    11221 tacgttcata gtcaaatcgc gtgtgaagtt attcatctcc acattccctc gaactcggag
    11281 ccaagaattc ttcttgatga ggtcaaactt ctgggcctct tcctcgtttt taacccactt
    11341 ttgcatagaa aaacttgaag tatagtccgt cattttaaag ttgattaaaa cacgacctgt
    11401 tctagtcact ttttgctcca cattaaaaac aaccccttca aataccagac gattttcctc
    11461 tgtcgtcact tcgatcatag gagtaatctc cgccttatcc agcttgggtt tagctgcagc
    11521 ttttttcgct tgaaaatcaa agactggttt ctcttccgct ggaggaggtg ccatctgctc
    11581 cagttgttcc atagcacgga gcgcttcctc attggcagct tgaacaatct gctcattttc
    11641 agcatgaaag gcctcttcct gctcttgggt caggacatca ttcttctcga cttgacagtt
    11701 aaaagttgga aaaccaaact tttcaagttg tttggctaaa ttaggaagat gattcttctt
    11761 aaaatgttcc ttatcaatcg cttcagatcc ttcaataaat agctgattac cctcagcacg
    11821 aacttgcaaa ttttgataaa gggacttaaa accttgacta gcacatggac cttcagagaa
    11881 agcctcccta tagtaggact gcaagagctg atttgaaaat tcttgagacc gagccttaat
    11941 ttcaaaaaca gctttattgc ctgtcttaga aaattcttcg ctcaaacctt tctttaattc
    12001 taaaaagatt tcaatcggta aaatattaga aaatacgaaa tgaaactccc ataccttact
    12061 aattttatga accacaactc gctcaatatt agcctgtgct aaagcaggag cctgtctcat
    12121 ttcagcaggc atccccaatt gattcatcaa aatttcaaaa ctatttgaca ttcattttcc
    12181 tcacattatt cttctactat tttaccatat ttagaggtat tttctaaaga caaaaggaag
    12241 ccactaagtg acttccttct agagtgagga cggattagtc ttcaccttta tttttcttaa
    12301 taatttcttc ttgtactgac ttaggtacat cttcgtagtg gtcaaatacc atcatgaatg
    12361 taccacgtcc ttgagatgca gaacgaagaa ctgttgcgta accgaacatt tcagcaagtg
    12421 gaacgtaagc acgaacgatt tggctgttac cgtgtgcttc cataccatct acacgtccac
    12481 gacgagcagt tacgtgaccc ataacatcac caaggttttc ttctggaaca gtgattgtta
    12541 caagcatcat tggttcaagg atagctggtt gtgctgattt agcagcttct ttaagggaaa
    12601 gtgaagccgc aatcttgaag gcagtttcag atgagtcgac atcgtgatat gaaccatcat
    12661 aaagcttagc tttaacgtca accattgggt aacctgcaag aacaccgtta gccatagatt
    12721 ctaccaaacc tttttcaacc gctgggataa attcacgagg aaccacacca ccgacgattg
    12781 cgttttcgaa ttcgaatcct ttaccttctt cgtttggagt aaattcaatc cacacatcac
    12841 cgaattgacc tttaccacca gactgacgtt tgaagaatcc acgtgcttga gtagaagcgc
    12901 ggaatgtttc acggtaagat acttgaggag cacctacgtt cgcttcaact ttgaactcac
    12961 gacgcatacg atcaacaagg acgtcaaggt gaagttcacc catacctgag ataactgttt
    13021 caccagtttc aacgtttgtt tcaacgcgga atgttggatc ttcttcagcc aatttttgaa
    13081 gggcgatacc catcttgtct tggtcagctt tagattttgg ctcaaccatc aattggataa
    13141 ctggttctgg aacgttgatt gactcaagga tgattttagc tttttcatct gtcaatgagt
    13201 caccagttgt agtatctttc aaaccaacgg cagcagcgat atcacctgag taaacagtgt
    13261 cgatttcttg acggctgtta gcgtgcattt gaaggatacg tccgatacgt tcacgtttac
    13321 ctttagaagt attcaatacg tatgaacctg attgaagaac acctgagtaa acacggaaga
    13381 atgtcaaacg acctacgaat gggtcagtca tgatcttgaa ggcaagagct gcaaatggct
    13441 cttcgtcaga tgctggacga atttcttcag cgtctgtatc tgggttaata cctttgattg
    13501 ctgggatgtc aagtgggctt ggaaggtagt cgataaccgc atcaagcatc aattgaacac
    13561 ctttgttttt gaaggctgaa ccacacaata ctgggaagaa ttcaacgttg atagtcgctt
    13621 tacggatacc agctttcaat tcttcgttag tgatttcttc accttcgagg tatttcatca
    13681 tcaattcttc gtcagtttca gcaactgctt caatcaattt ttcacggtat tcttgagctt
    13741 ggtcaaggta ttcagctggg atgtcttctt caaggatatc cgtaccaagg tcgttagtat
    13801 agatttcagc tttcatcttg atcaagtcaa tgataccacg gaagtcatct tcagaaccga
    13861 ttggcaattg gattgggtgt gcatttgctt gaagacgatc gtgaagtgtg cttacagagt
    13921 aaaggaagtc agcaccgatt ttgtccattt tgttggcaaa tacgatacgt ggaactccgt
    13981 actcagtcgc ttgacgccaa actgtttcag tttgaggctc aacacctgat tgtgagtcaa
    14041 gaacggtaac cgcaccatcc aatacacgaa gagaacgttg tacttcgatt gtgaagtcca
    14101 cgtgtcctgg tgtgtcgatg atgtttacgc ggtggttgtt ccattgagct gttgtcgcag
    14161 cagatgtgat cgtgatacca cgttcttgct cttgctccat ccagtccatt tgtgacgcac
    14221 cttcgtgagt ttcaccgatt ttgtggattt taccagtgta gtaaagaata cgctcagtag
    14281 ttgttgtttt accggcatcg acgtgagcca tgataccgat attacgagtt ttttcaagtg
    14341 aaaattcgcg tgccatgagg tttgtttctc ctatttattt ttgatttcta ttctattata
    14401 acacgatttt aataaaaacg gataggcagg acctacccgt tctcaatgtt ttcatgctat
    14461 tgttggtttc aacttacgag atggtaagct gagttatagc taatactaat cgatttagct
    14521 aatttgaacc cgggctaaag ttagttagcc gatatgagct ggaacgggat gctgcgtgaa
    14581 aaagataaaa ctccttgtat tcatcgaata ctgcgtcagt ttcctatttt caccttgcat
    14641 ccttaccgtt cctagcatca tgatttagtt gagctcaagc taaaagtctg gagaaaaaga
    14701 tgaatctcat tggttgcaac cgcaacctgc ttcgattccc tattttctct gggactttct
    14761 taacgctttc gcatcctatc ttaccaacgg aagtgtgcga atgcacggtt agcttcagcc
    14821 atacggtgag tatcttcacg tttcttaact gctgcaccag tgttgttagc agcatccaag
    14881 atttcttttg caagacggtc ttgcattgtg tgttcaccac gaagacgagc gattgttacc
    14941 aaccaacgaa gtccaagtgt tgtacgacgt tctggacgaa cttcaactgg gacttggtag
    15001 ttagaaccac caacacgacg tgcacgtact tcaagtacag gcatgatgtt ttccatagct
    15061 gtttcaaata cttcaagtgc atcgttgcca gtagcttctt tgatttgctc aaaagcaccg
    15121 taaacgattg aagcagcagt accacgttta ccatcaagca taacgcggtt gataagacga
    15181 gtaactagtt gtgaattgta tagcggatct ggcaatacgt cacgttttgg agctctattt
    15241 ttacgactca tttctcttta tcccctttcc ttatgctttt ggacgtttag taccgtattt
    15301 agaacggcct tgtttacgat cgttaacacc tgcagtatca agtgcaccac ggacgatatg
    15361 gtaacgtacc cctggaaggt cttttacacg tccaccgcga agaagcacca cgctgtgctc
    15421 ttgcaagttg tgtccgatac ctgggatgta ggcagtaact tcgataaggt tgctcaaacg
    15481 tacacgagcg aatttacgaa gggctgagtt aggtttttta ggtgtcattg ttccaacacg
    15541 agttgcaaca ccacgttttt gtggtgaaga aacgtttgtt tgaacttttt tatgactatt
    15601 gtaaccaacg ttcaaagctg gtgatttaga tttttctact tttgatttac gcggtttgcg
    15661 aaccaattgg ttaattgtag gcatctacat tctcctgtgt ttttttattt ttggtgatga
    15721 tacacttggt gacagatatc atctgtgtgt acttttgcaa catttgtcag cacgtccctg
    15781 tacactcttg agagaccaaa agtaaaaagt accgtctatt attgtaacaa aattttccct
    15841 tgcttgtcaa gatatttttc ttttttattg gtaatgttag agatcaattt ctgaataaaa
    15901 atagctgaga acacatcatc ttcctaataa cacggcttgg cttacgtgac atttttatct
    15961 ccgtcattta tactgatata taaaatagta cggaaaactt ctcaaaagta agaatttctt
    16021 tcacaaatca aagaaaacgc ttgcatattg ttttactaca tgctatactg atatagaaat
    16081 ttattgattg gagaatcatt atgagaaaaa caccatctca cactgagaaa aaaatggtct
    16141 acagcatccg ttccctcaaa aatggaactg gttctgtcct tatcggcgca agccttgtct
    16201 tgcttgccat ggctacacca actatctcat ccgacgaaag tacaccaacc actaacgaac
    16261 ccaacaacag aaatacaacc acccttgccc aacctcttac tgatacagca gctggctctg
    16321 gtaagaacga aagtgatatt tcttcacctg gaaatgcaaa cgcttcccta gagaaaacag
    16381 aagaaaaacc tgctgcaagc ccagccgatc cagcaccaca aactggacaa gatcgttcaa
    16441 gtgagccaac tacttctact agtccagtaa caactgaaac taaggcagaa gagcccatcg
    16501 aagataacta cttccgtatc catgtcaaaa aacttcctga agaaaacaag gatgctcaag
    16561 gactatggac ttgggacgat gttgaaaaac catctgaaaa ctggccaaac ggagctttgt
    16621 ccttcaagga tgccaagaaa gatgactacg gctattacct agatgtcaaa ttaaagggag
    16681 aacaagccaa gaaaattagc ttcctcatca acaatacagc tggaaaaaat ctaaccggcg
    16741 ataaatctgt agaaaaacta gttccaaaaa tgaacgaagc ttggttagac caagattaca
    16801 aggttttctc ttacgagcca cagcctgcag gaactgttcg cgtcaactac taccgcacag
    16861 atggcaacta tgacaagaaa tctctctggt actggggaga tgtgaaaaat ccaagtagcg
    16921 ctcaatggcc tgacggaaca gactttacgg ctacaggcaa atatggccgc tatatcgaca
    16981 ttcctcttaa tgaagccgca agagaatttg gatttttatt actagatgag agcaaacaag
    17041 gagacgacgt gaaaatccgt aaagaaaatt ataagttcac agatttgaaa aatcatagcc
    17101 aaattttcct aaaagacgat gatgaatcga tttacacaaa tccatactat gtccatgata
    17161 tccgtatgac aggagcccaa cacgtaggca cttctagcat tgaaagtagc ttttcaacac
    17221 ttgtcggtgc taaaaaagaa gatatcctca aacactccaa catcactaat cacctaggaa
    17281 acaaggtaac tattaccgat gttgcaatcg atgaagctgg taagaaagtg acctacagcg
    17341 gagatttctc tgacacaaaa catccttata ctgttagcta caattccgac caattcacta
    17401 ccaaaacaag ctggcgcctg aaagatgaga catacagcta tgatggcaaa ctgggagctg
    17461 acctaaaaga agaaggaaaa caagttgatt tgaccctttg gtcaccaagt gctgataagg
    17521 tttctgttgt tgtctacgac aagaatgacc ctgacaaagt agttggaact gtcgctcttg
    17581 aaaaagggga aagaggaact tggaaacaaa ctctagacag cacaaacaaa ctcggaatca
    17641 cagatttcac tggctactat tatcaatacc aaatcgagcg tcaaggtaaa actgttcttg
    17701 cactcgatcc ttacgctaaa tctcttgctg cttggaatag cgacgattcc aagattgacg
    17761 atgcccataa agtggctaaa gccgcctttg tagatccagc taaactcgga cctcaagact
    17821 tgacttatgg taagattcac aatttcaaga ctcgtgaaga cgccgttatc tacgaagctc
    17881 atgtgcgtga tttcacttca gatcctgcca ttgcaaaaga cttgaccaaa ccatttggga
    17941 cttttgaagc cttcattgaa aaactagact atctcaaaga cttgggtgta acccatatcc
    18001 agctccttcc agtcttgtct tactactttg tcaatgaatt gaaaaaccat gaacgcttgt
    18061 ctgactacgc ttcaagcaac agcaactaca actggggata tgaccctcaa aactacttct
    18121 ccttgactgg tatgtactca agcgatccta agaatccaga aaaacgaatc gcagaattta
    18181 aaaacctcat caacgaaatc cacaaacgtg gtatgggagc tatcctagat gtcgtttata
    18241 accacacagc caaagtcgat ctctttgaag atttggaacc aaactactac cactttatgg
    18301 atgccgatgg cacacctcga actagctttg gtggtggacg cttggggaca acccaccata
    18361 tgaccaaacg gctcctaatt gactctatca aatacctagt tgatacctac aaagtggatg
    18421 gcttccgttt cgatatgatg ggagaccatg acgccgcttc tatcgaagaa gcttacaagg
    18481 ctgcacgcgc cctcaatcca aacctcatca tgcttggtga aggttggaga acctatgccg
    18541 gtgatgaaaa catgcctact aaagctgctg accaagattg gatgaaacat accgatactg
    18601 tcgctgtctt ttcagatgac atccgtaaca acctcaaatc tggttatcca aacgaaggtc
    18661 aacctgcctt tatcacaggt ggcaagcgtg atgtcaacac catctttaaa aatctcattg
    18721 ctcaaccaac taactttgaa gctgacagcc ctggagatgt catccaatac atcgcagccc
    18781 atgataactt gaccctcttt gacatcattg cccagtctat caaaaaagac ccaagcaagg
    18841 ctgagaacta tgctgaaatc caccgtcgtt tacgacttgg aaatctcatg gtcttgacag
    18901 ctcaaggaac tccatttatc cactccggtc aggaatatgg acgtactaaa caattccgtg
    18961 acccagccta caagactcca gtagcagagg ataaggttcc aaacaaatct cacttgttgc
    19021 gtgataagga cggcaaccca tttgactatc cttacttcat ccatgactct tacgattcta
    19081 gtgatgcagt caacaagttt gactggacta aggctacaga tggtaaagct tatcctgaaa
    19141 atgtcaagag ccgtgactat atgaaaggtt tgattgccct tcgtcaatct acagatgcct
    19201 tccgacttaa gagtcttcaa gatatcaaag accgtgtcca cctcatcact gtcccaggcc
    19261 aaaatggtgt ggaaaaagag gatgtagtga ttggctatca aatcactgct ccaaacggcg
    19321 atatctacgc agtctttgtc aatgcggatg aaaaagctcg cgaatttaat ttgggaactg
    19381 cctttgcaca tctaagaaat gcggaagttt tggcagatga aaaccaagca ggatcagtcg
    19441 gaattgccaa cccgaaagga cttgaatgga ctgaaaaagg cttgaaattg aatgccctta
    19501 cagctactgt tcttcgagtc tctcaaaatg gaactagcca tgagtcaact gcagaagaga
    19561 aaccagactc aaccccttcc aagcctgaac atcaaaatga agcttctcac cctgaacatc
    19621 aagatccagc tccagaagct agacctgatt ctactaaacc agataccaaa gtagctgatg
    19681 cggaaaataa acctagccaa gctacagctg attcacaagc tgaacaacca gcacaagaag
    19741 cacaagcatc atctgtaaaa gaagcggttc gaaacgaatc ggtagaaaac tctagcaaga
    19801 aaaatatacc tgcaacccca gatagacaag ctgaacttcc aaatacagga attaaaaacg
    19861 aaaacaaact cctatttgca ggaatcagcc tccttgcgct ccttggtctc ggtttcttac
    19921 taaaaaataa aaaagagaac taaactagcc ctcctataga aaaatccccc aagcattata
    19981 gctcggggga ttaattttcg tacaatattt gttgtcctaa taaacttgat taggattttt
    20041 tattaagcct ctttcatagc aaaataagct cgtactttgg gtgcaacttg tgttccgaag
    20101 agttcaatag ctctcagaac ctggtcatga ggcatagaac caagcggtag atgaagcatg
    20161 aagcggtcca atcctaaatc ctctatcatg cgaatcaatt tttcggccac ctgatctgga
    20221 ttgccaacaa acatggcgcc atttgaccct acctgctcca aatattgctc ataacgcaat
    20281 tcctgccagt gcggacggtc tttggaaata gcatccacca cttgcttagt cggatggaaa
    20341 taatctttca ccgcctgctc accatcttcc gcaatccacc cccaagaatg ggctcccact
    20401 ttcaagtctt tgtcagcatg gaccgcttcg cttccaatct cacgataagc ctgaatcaac
    20461 tttttaaaat aacgtggatt accaccaata atagcatata caatcggtag accagcctga
    20521 gcaatcttca ctgttgattc gacatgacca cctgtagcta tccacaaggg caatttgtcc
    20581 tgaactggac gaggataaac ttctttacca gcaatcgttt gagtcaatcg accttgccag
    20641 tctaacttgg tcttttcatt gactaactga agcaagtcta atttctcatc aaaaagagag
    20701 tcgtagtctt tcaagtcata accaaacaga gggaaagatt ccgtgaaaga gccccttcca
    20761 gccataatct ccgctcgtcc atttgacaaa gcatcgatag tggcatactg ttggaacaaa
    20821 cgaatcggat ccatgcttga cagaatgctg actgcactgg tcaaacggat tttcttggta
    20881 ttgactgccc cagcggccag gacaatctct ggggctgata ctgcaaaatc cgcccgatgg
    20941 tgctcgccaa tcccatatac gtccaaacca accttgtcag ccagctcaat ctctgccacc
    21001 aactggcgaa tgcgttcagc atgactgtaa gtttgtccag tcccttcaag ctccgttatt
    21061 tccccaaatg ttgaaattcc caattctacc attgtgattc tccttgtcta tctctgtcct
    21121 tcaatttgaa aaattattct aacactcaat gaaaatcaaa gagcaaacta ggaagctagc
    21181 cgcaggttgc tcaaaacagt gttttgaggt tgtggataga actgacgaaa tcagtaacca
    21241 tacctacggc aaggcgacgt tgacgtggtt tgaagagatt ttctaagagt ataacacgaa
    21301 tcttgagtac aagcaaccaa tttgctcaca agaaaaagcc tagataacta gactttttta
    21361 gcttattcta ccgttactga cttggcaagg ttacgtggtt tgtccacatc gaggccacgg
    21421 tggagggttg caaagtaagc gactaattgc gttggtacga ccattgaaat tggtgagagg
    21481 tatggatgta cggtcgtaag gacgatatcg tcggtatctt tggctacatt ctcttctgcg
    21541 atagtgagga ctttggcacc acgggctgcg acctcttgga tatttccacg agtatggttg
    21601 gcaagaactg gatctgacaa gagagccaaa acaggcgttc cttcttcaat caaggcaatg
    21661 gttccgtgct tgagttctcc tgccgcaaaa ccttcacact ggatataaga aatctctttg
    21721 agtttgagac ttgcttccat ggctacgtaa taatcttgac cacgtccgat gtaaaaggcg
    21781 ttacgagttg tttcaagaag ttcacgaacc ttggcttcaa tggtttcttt ctctgaaaga
    21841 gttgattcaa tagactgagc tacgattgac aattcatgaa ccaggtcaaa ggcttgcgct
    21901 ttagcattac catttgcttc tccgactgct tttgcaagga aggcaagggc tgcgatttgc
    21961 gctgtatagg ctttagttga tgccacggca atttcaggac ctgcgtgaag gagcatggta
    22021 tagttggctt cacgtgagag ggttgaacct ggaacatttg tcactgttaa gcttggaatt
    22081 cccatttcat tagccttgac caaaacttga cgactatccg ctgtttcacc agattggctg
    22141 ataaagatga agagtggttt cttgctgaga agtggcatac cgtagcccca ctcagatgag
    22201 attccaagtt caactggtgt atctgtcaat tcttccaaca tcttcttaga agcaaatcct
    22261 gcatggtaag atgttccagc tgcaaggatg tagatgcggt ctgcgtcttg aacagcctta
    22321 atgatatctg ggtctacgac aacttgacca gcctcatctg tgtaggcttg gatgagtttc
    22381 cgcataacag ttggttgctc gtcaatttcc ttgagcatgt agtaagggta agttccctta
    22441 ccgatatctg acaagtcaag ttcagcagtg tagctagcac gctcacgacg atttccatca
    22501 tagtcttgaa cttccacgct atcagccttg acgattacca actcttggtc atgaatttcc
    22561 atgtattggt tggtttcacg aatcatagcc atagcatctg agcagaccat attgtagcct
    22621 tccccaagac caatcaaaag tggagatttg tttttcgcta catagatgac atctggattt
    22681 tcagagtcaa tcaaggcaaa ggcatatgaa ccacggataa tatgaagagc ttttttaaag
    22741 gcttcaagaa ctgagagacc gtcttcttcc gcaaattttc caatcaaatg tacggcgatt
    22801 tccgtatctg tttgcccttt gaagtggtgc ccagcaaggt attcttcttt aatttcaagg
    22861 tagttttcaa tcaccccatt gtgaaccaag acaaaacgtt ctgtctcaga gcggtgtggg
    22921 tgagcattgt cttccgttgg tttcccatga gttgcccaac gagtatgtcc gataccagtt
    22981 gttccctcaa caccagctgt cttggcagac aattctgcga tacgaccaac agccttcacc
    23041 aaatggttat cagcaccatc taggacaaaa attcccgcag aatcatagcc acggtattca
    23101 agcttttcaa gcccttgaat caaaatatca gttgcatttg tgtttccaac aacaccaaca
    23161 attccacaca tagtatatac gacacaggca agctgtgctt tctccttaaa attggtatag
    23221 tctaattcat cttttataga atcagcaaaa acagtatata cttgtttctt tcacttgtca
    23281 agagtaaaaa ttggtatagt tcaaattaag ctcctgtaag caaaaaactc tgaccgattg
    23341 ggataatcag tcagagtcct ttttaaaatc cattattatc gcttaatttt ttgaaccagt
    23401 ggcctgattt cttcagacga cgttcttgcg tttccaagtc taattcgacc aaaccatagc
    23461 gatttttata gctgttgagc catgaccagc agtcaataaa ggtccaaatc aagtagccct
    23521 tacagttggc accatcttca atggcacggt gaagttcacg aagatgacct tttacaaagt
    23581 caatacggta atcatcttga atcattccat cttgacggaa tttttcttcc ccttcaacac
    23641 ccataccatt ctcagtcaac atccattcaa tattgccata attttccttg atattttggg
    23701 cgatgtcata aatcccttgc tcataaatct cccaaccacg gtgagaattg attttacgtc
    23761 caggcatcac ataaggctcg taaaaatgtt ctggtaagag tggactctct ggatgcttag
    23821 caaatcgagg agccataaca cgcaaaggtt gatagtagtt cacaccaagg aagtccaccg
    23881 tattatcatg aatgagttcc aactcttcct ctgtagcatc aggtaaaaga ccgtgttcat
    23941 gcaagatttc taccaactcc tgtggataag tccccaagac agatggatct aagaaagatt
    24001 gggcctgaaa aagggccgca atacgagctg ccttgacatc agcaggatgc tggctacgtg
    24061 gataagccgg tgtcaagttg aggacaatcc caatcttgga atcaggcaaa agttcatggc
    24121 aagccttaac agcccggctg ctggccaatt gtgtatgata ggctacctta acagctgcct
    24181 ctgcatccac cttatgtgga taatgggcat cataaaaata accaaattct acaggaacga
    24241 tgggctcgtt aaaggtaatc cattgatcca ctaaatctcc ataagtctca aaacaaaaac
    24301 gagcatagtc ttcataggct gagactgtcg ccttattttc ccaaccatca ccatcctctt
    24361 gaagggcaaa aggtaaatca aaatgataga gattgactaa cagacgaatt cctttagcct
    24421 taatagcctc aaagacctta cgataaaaat ccacaccttg agggttgact tttccacagc
    24481 cttgtggaaa aatccgtgac cactgaatag aagtccgaaa gactgtgtga ccagtctcta
    24541 acaaaagctc aatatcccgc tcccaatttt cataaaaagt cgatgtctta tctgaaccaa
    24601 tcccattata gtaacgattt ggctccactt ggaaccagta atcccagaga ttgtctccct
    24661 taccgtcacc agctacacgt ccttctgtct gcggtccaga agtagaggat ccccagacaa
    24721 aatcctttgg aaatcttagc ataacattta cctctttatc tactcatttc tcccattata
    24781 cagaaaaaac aaggtaaaaa ctagttacat tttttccttg tttttcttct gattatagtt
    24841 tttatttctt gcttaggatt tcaagcgttt caagcacgtt atctgcatga acctcaatgg
    24901 tgtcaccagt tgccttgatc ttaacttcta caatgccatc ggccgctttt ttaccaacag
    24961 tgatacggat tggaagacca atcaagtcac tatcgctaaa tttaacaccg acacgttcgt
    25021 tacggtcatc tgtcaagact tcataaccag ctcccatcaa gcttgcttca agtttttctg
    25081 tcaaggcttg cgcttcttca tccttgacat tgacagtaat caaatgcaca tcaaatggtg
    25141 ccaattcttt agggaaattg attccccaag cgtaacggta ttcacctttt ggcgttttgt
    25201 taacaaagag gcgagcgtgt tgctccatca ctgctgaaag aagacggctg acaccgatac
    25261 cgtaacatcc catgatgatt ggcacagcac gaccattttc atccaagaca tctgctccca
    25321 tgcttgctga gtagcgagtt ccgagtttga aaatatgacc gatctcaata ccacgcgcaa
    25381 agttaaggac accttgtcca tctggggaaa tttcaccctc acgaacttca cggatatcca
    25441 catattctgc agtaaaatca cggcctgggt tcacaccagt caagtggtag ccatcttcgt
    25501 tagcaccgac aactgcattg cgaacatctt gcaccttacg atctgcaata attttaatat
    25561 tctctggcaa accaactggt ccaagtgaac caaatcctgc ttgaacaaca ttcgccactt
    25621 cttcttcgct agcaacgtca aagaaatctg ctcctaagtg gtttttcaac ttgacttcgt
    25681 tgagttggtc atttccaact agaagggctg caacaagctc accatctgca atgtagaaga
    25741 gggttttaat cgtttgttct tctggaacat tgaggaaagc tgcaacttca tcaattgatt
    25801 taacatctgg cgttgcaaca cgagtaactt cttcttcagc gacaacacgg ttgcttggtt
    25861 tgtactcgtt tgttgccatt tctaagttag ctgcatagct agactcactt gagtaagcaa
    25921 tggtatcttc accagagact atccatttga gcaattctgc cttgatttct tcttgcactt
    25981 ctgcaggaat ttcgtcaaat gaggcaactg acttgtccaa gacaacccag cggtcaaggt
    26041 ctgtacgagc agatgtaatg gccataaatt cttggctatc cttaccaccc atggctccac
    26101 cgtcaccaat aatagccttg aagtctaaac cactacgagt gaaaatacgc tcataggctg
    26161 ctttgtactc atcataaaca ctatccaaac tatcatagtt agcgtggaaa ctataagcat
    26221 ccttcatgat aaactcacgt gtacgaagaa gtccattacg tgggcgtttt tcatcacgat
    26281 acttgggctg aatttgataa aggttgagtg gcaattgctt gtaagattta acagaatcac
    26341 ggacaatagc tgtaaaggtt tcttcgtgag ttggacctaa gataaagtct gatttttcac
    26401 ggttttttag tttgtaaagg tcttcaccat aggtttcgta acgacctgat tcacgccaca
    26461 attctgcact aagaagggct ggagccaaca tctcaacagc accaatcttt tcgaattctt
    26521 ggcgcatgat gtttttagct ttttcaatca cacgattggc aagtggtaga taagaataaa
    26581 cacctgctga aacttggcga acataaccag cacgcaacat aagagcatgg ctgataactt
    26641 gagcatcgct tggcatttcg cgaagcgttg ggataggcat tttactttgt ttcataatat
    26701 tcctcgatta tctaaaaaag agtcgcataa tgtcattcca agtcacagca atcatcaaga
    26761 caaccatgat gaccactccg gccaaggtga cataggtttc aatttcttgt ttcaatggtt
    26821 tgcggcggat ggcttctagg atattgagca caatcttacc accatccaag gctggaatcg
    26881 gaataagatt aaaaatccca atattgatgg aaatcattgc caagaagtac aagatatttt
    26941 caattccatt tttagcagca tcactacttg ccttaaagat agcaacaggt ccacccaact
    27001 tgttcaaatc cggttggaaa atcagatttt tcagagctga gagaattcgg agagctgagt
    27061 cagcagcagt tgtaaaacca cctacaaaca tggatagaaa atctgactta acccccggtt
    27121 gaacacctag aaggtaacga ccttgactat cttcgggtgt aacagtgact tgtttgtcac
    27181 tccccttttc agaaatagtc acatccaaag tcggtgccgt cttatctttg gtttctgttt
    27241 ccacagcttg gatcaagctt tcccagttgc taacctcatg tgagccaatc ttggtaattt
    27301 gtgccgtttc tggtactcct accttggcca aggcaccttg gggcatgata tggaactgat
    27361 tggtatcaac atctctgaca ccaccctgca taaagattaa aacccaaaaa acaacgacac
    27421 ctaagataaa attgttcata ggacctgcaa aattggtaat cagtttgccc cagatagtcg
    27481 cattttgata ttgaacatct aaaggtgcaa tccgaacctc agtaccatct gcttccacaa
    27541 ccgttgcatc gtgatccact gcaaatgttt tttcttcttc cagaaccaat cctttgataa
    27601 agagcttgtc ttcaaaatca aactgggtca cctgcatagg gagggctgtt tgatccaatt
    27661 ttttacctga gagattgatg cgtttaacct taccatcatc agcaagtgtc aaactaacag
    27721 gcgttcctgt cttgatttca gttgtatcat caccccaacc ggccatgcgg acatagccac
    27781 ccagaggcaa gattcgaatg gtataggccg ttccatcctt gccaatgtga gcaaaaattt
    27841 taggtcccat accgatggca aattcacgta ctaaaatccc tgatttcttg gcaaagtaga
    27901 agtgcccgaa ctcgtgcacc actacaataa tcccgaaaac cagaataaag gttaaaattc
    27961 cgagcatagc gtttcctccg tcttttgatt aaaagagtcc aaataagtgc atgattggaa
    28021 atacaagcaa catactatcg aaacgatcca aaacaccacc atgtccaggg ataaatttcc
    28081 cagaatcctt aacaccaaaa tgacgtttga tcgaactttc tagtaaatca ccaaattgtc
    28141 cagcaatgct aaagaaaata gcaaagactg acatcttgta aattccatat ggaagagcaa
    28201 ctgtactgtc aactatcata aagataatgg ttactaaaat tgctcctaaa ataccaccca
    28261 aggcaccctc aagggtttta ttaggcgata cccttggtgc taactttcgt ttcccatagt
    28321 tcatcccaac aagataggca ccactgtctg tcgcccagac gatacacaag gctaagagag
    28381 ccttgtccaa acctgcaaca cgagcatcta gtaaagcatt aaacccaaag cccacgtaga
    28441 agctcatagc aagagggaaa accgcatcct caatcgtata agacttgcta aaaacggtcg
    28501 ttcctaacat gattgaaatc aaaacactat aggcaaccac attcccatca actggcaaaa
    28561 aagtcaggta attctccaag ggaatggtca atgcaaaggt tgcaaagagg gtcaagaggc
    28621 cctccatcgt catggtcgct agacctctca tcttcaaaag ttcatgcatg gctagcatgg
    28681 ctacgattcc gattgctatc tgaagcaaga ggcccccaat cattaaaatt ggtaggaaaa
    28741 tagccagggc aatccctgca aacaaggttc ttttctgtaa atcctgggtc atatttcctc
    28801 ctaaactcct ccaaatcggc gatgacgacg attataggca agaatagctt cctgcaaggc
    28861 cgcttcgtca aaatcaggcc ataaggtgtc cgtaaaataa agctcactat aggctccctg
    28921 ccatggaagg aaattgctca aacgtaattc tccactagta cggataatca agtctgggtc
    28981 tcgtaagtcc ttaggcaaat gctgggtaaa gagatagtta ccaatcaatt cctctgtgat
    29041 gtcacctgga ttgattttgg catctaaaac atcctgggaa atcaacttaa gcgcctgtgt
    29101 aatctcagca cgtccaccat agttaagagc aaaattaaga atcaatcctg tgttgttctt
    29161 agtcaattcc tcagccttgg ttaaagcttc aaaggtttgc ttaggcaggc ggtctgtctc
    29221 cccaatcatt tgaatcttaa cattattcgc atgtagttcc gggacataat tatcataaaa
    29281 ctctactggc aagttcatga taaacttgac ttcctgatct ggacgggtcc agttttccgt
    29341 agaaaaagca tagaccgtaa taaccttgac gcccagtttg ttggctgcct tggtcacggt
    29401 ttgcaatgct tccatgcccg ccttatgtcc aaaaactcgc ggttgcatac gttttttagc
    29461 ccaacggcca ttgccatcca tgatgatgcc gatatgagca ggaacctgtg tcggaacctc
    29521 tacttccaca gccttatctt tcttaaaaaa tccaaacatg atcttattcc tattcaaaaa
    29581 tctatcgttt cattatacca tatttcccca ttttcttcta tcactaagct atttattctc
    29641 aggcaccaag cccatttttc aaaaaaataa gccgcctgat tgggcgactt tatttttata
    29701 gggagattat tatgaaaaag ttttaggagt ttaagttaag gtcttcttaa cttatgaact
    29761 tagtgtacac tccctagctt aaagtttcct taagtatttt taaaaatcaa atttttccat
    29821 ttctcctgcc aatttttctt ggataaacgt gtttgataga gttccattcg gtcttcattt
    29881 tctaagaaat gaggagttgg acgaacttga aaattcaaaa tatcctccaa accataaggt
    29941 acatagagtt caaaatctaa ttcttcattc aagcgcagtc caactgccgt acaccgttct
    30001 ggatacttac tcatagcatc acgagaactg gtataggaag cagtgtgagg actgtgctga
    30061 tgcatataga cctgattttt caattcccac tggtactgag gaaaatcctc tctcagcttt
    30121 ttctccagta ataaggtttc ctcataagaa aaatctggat caaagaaaat cacatctata
    30181 tctgtttcat gatcaaaagg ggatttgtct gacaaaagat tccagatgaa atttctgaca
    30241 gaacctgctg ccaaccacga gtctttcaaa ccaaggtctc ggatgatcgt cagaatggcc
    30301 atcatatctg gactttctct aaaagcctct aagatttctt gcttattttt cactgtattc
    30361 ataacctaag tgctcatatg ccttagcagt cgccacccgt ccagaccgtg tccgcatgat
    30421 aaaacctttt tgaatcaagt aaggctcata catgtcttca actgtctcac gctcttcggc
    30481 gatattcaca gaaagagttc ctagaccaac aggtcctcca ctgtacatct caatcatggt
    30541 gcgaaggatt ttttgatcca catagtccaa accttcatgg tcaacatcca gcatagtcaa
    30601 agccttatcg gtaataacat catcgataac cccattcccc attatctggg caaaatcgcg
    30661 cacgcgcttg aggagacgat tggcaatacg aggggttcca cgactacgta gggccaactc
    30721 agatgctgcc tcatgggtga tttccatctc aaaaatatct gccgtccgct cgacaatttc
    30781 tgtcaagtca gcatgagcat aatactccat atgacctgta atcccaaaac gtgcccgtag
    30841 tggatttgag agcataccag cccgagtcgt cgcaccaatc aaggtaaaag gaggcaactc
    30901 caaatgaaca ctgcgactgc cttcaccagc cccaatcata atatcgatgt agaagtcctc
    30961 catggcacta taaagcactt cttccactga catgggtaag cgatgaatct cgtcaataaa
    31021 gaggacatct ccaggctcta aatcattcaa aatcgctacc aaatcacccg ctttttcgat
    31081 aacaggacca gacgtttgct tgagattgac tcccagttca ttggcaatga caaaagccat
    31141 ggttgttttc ccaagccctg gagggccaaa taagagcaca tgatccagcg cttcatcccg
    31201 cattttagcg gcttcgataa agatctgaag ttgatcctta accttatcct gaccaatata
    31261 ttcacgtaaa tactgaggac ggagcgtgcg ttctactaac tcctcatcac ccatcatctc
    31321 attatctaaa attctactca tggctctatt atatcaaaaa aaacaagcca caaacaaaaa
    31381 agccacctga ttgggtgact cctaagttta gcacttatgt ggtataatat tatacggcac
    31441 ttctacaccg cctacgaaag gaggtgagat agcccatgat ggaattagta ctcaaaacta
    31501 ttatcggacc aattgtggtc ggtgtcgttc ttcgtatagt cgataaatgg ctaaacaagg
    31561 acaaatagtg tcaaaaaaga cctcaagctt atttggtcgt gagcttgggg tcttttctag
    31621 cctatgatat agaactagta ctcaattcct ttttattatc ccatagttca cgaattttgt
    31681 caaaacttta cattttcttc aaccgctgta cgacaagacg gttaagatta agagaacgtt
    31741 agggattcta tcaatttcat agaaattttg atttcgtaaa cgaagagaca atcttacatg
    31801 tcacttctca tttaatacgc cactactaga caagcaaaat cattattaca gtagttccag
    31861 tccttcaatt aacagtcact tacaatcaaa ttgagtttga actagctgaa gcgaccacag
    31921 acctatttct tagtcatatt cgctaaaaaa atccccgcca aaatctcaaa aagtccccgc
    31981 caattccccg accaaaatcc gaaaaatacc gaaaaatatc gaaaaattat ttttagaata
    32041 gtcccaaaaa tcctgaaata gagctaaaaa actccacctg attcggtgga gttaagggag
    32101 attattatga aaaagaaaag tttaggattt tattaaataa agttaggagg tctttattta
    32161 ataactacat gatacaagac gaaacttaaa actagcttaa cttttctaaa attttactat
    32221 tttgcaaaaa atttctatca ccagcacctc accaatcgag taggggataa tctctagccc
    32281 ctctcacacc accgtacgtg ccgtttggca tacggcggtt caactaactt ttaacgcatg
    32341 tcgttcaagg taataatcca aacacgaaac cagtccacgt ttttccagga ctggttttga
    32401 tatagcacgt ttaagtaccg acttctgagc tactaattga taatggtcgc cccagccaga
    32461 taccttatct gctatccatt taggaactcc taacttaagc aatccccata atcgtctcga
    32521 tttcttcttc cattgcttcc agataatcac tcgtaggcga gtacgcaagc gctcatctat
    32581 gctggcgact atacttttca tatttcccaa tgagcaatag tttatccatc ctcgaataga
    32641 caaattcagt tgctcaatac gtcttgttag gtctatactc catttcctct gtgttagttt
    32701 cttcaattta aacttaaatc tccgaacact atcttgatgt ggacggcttt tccaaccatc
    32761 tgataatttc cagaacccaa aacctagata tttcaactct cttggtcatg tttactttca
    32821 aacctagccg tttctcaata aaacgactga ctgaatacat catacgctta gcggctgcct
    32881 cgcttacgac cgtaatcaca caatcatctg cgtagcgcac aaatcgaagt cccctctttt
    32941 ctaattcctt gtccaattca ttaagcatga tattggataa gagaggagat aaatttcctc
    33001 cctgtggtgt accaactagt gttttataac gttgaccatt aatgataaca cctgaatgaa
    33061 gatacttacg aatcaaggat tccgtatctc cgtcttcgat aatgttatgt actaaggaca
    33121 tcaatctatc ttgaggaact gtatcgaaaa atttctctag gtctatatcc actatccact
    33181 catagccgtc atttaagtat tctaagagct tcatgatggc tttttcacat gacctatttg
    33241 gtctgaaacc ataactcgta tctgagaaat ggggttcaca aatggggctc atgacttgga
    33301 caatggcctg ttgaatcatt ctatccataa ctgttggaat tcctagttga cggatgcctc
    33361 cgtctggttt aggtatctca actctaagaa ctggttgagg cttatatttt ctctgtttta
    33421 tcagttcctt agtcaagcgc cagttttgtc tgagataatt atccatctct tcgatagtca
    33481 ttccatcaat cccagctgag cctttattgg attttacttg attgtaggct tccagcatat
    33541 tttcgcgtga taatatctta tctagcagtt ttgacatgtg cgtattcctt tcttattttg
    33601 gtgcctgagg gacatcttat attggtgaac cttcatctag tcattacgtg tcaaagtcca
    33661 gttctatcag accactcatt ttacagacac aagtgaagta ggattacttc gattagttgt
    33721 tcaccccttc gctccacttc cattacggaa gtttcctcac tactatgggc tcggctgact
    33781 tctcatgatt cgttgttact acgctttcag cgctcatgaa acctcacggg ataagtcgta
    33841 catctttcct cgtttataca agatatgagg acgttaaaag gttacagtga aaataggaaa
    33901 tctgacgcag agtctttaga ctctagaaag atttatcttt ttcacacaaa ccttagtccg
    33961 aattcaatta ctctcgtgat ttacacatat aggttacgac tacctttttg gactttagag
    34021 tttgaagcct ccttatccgc tatatacgcc ttactatcac gttcctgttc gtagagccac
    34081 gatttcgcta tcccttcctc tccctgctac ctcacgatag tcaggctgag gacttacacc
    34141 tcagatatac gacatgcccg tcgtaccgca aaaaagccac ctgattgggt ggcttcatta
    34201 ggagattgtg atgaaaaaag tttaggattt tattaaataa agttaggagg tctttattta
    34261 atgactatat gatactagac catccttaaa ctttgcttaa gaacaaacaa gtttttttat
    34321 ttttctctgt ttatccaaat cattcctgta cagtcatagg tggataagat ttcaaagccc
    34381 atagaacgat aaaatcccac gtttttttct gtctcttctg tcgccagctg gacttgatag
    34441 gcctctttaa aatttcctaa agcctctttc atcaaggagc taccaatccc ttgacgctga
    34501 tagctaggca aaacaatcaa atcctgtaca aaaactgatg aaaaaccatc tccaaccaaa
    34561 cgaatcaagc ccaccacagc atcaccatca agtgccagat aaattactaa tgaatgagat
    34621 aaggcctgct ccagcatctc tgtttgatgg gtatagtttg tccaaccgac atcctgatag
    34681 agatgcaaaa catcctctag cttgacaatt tcttgctttt taatagtaat catctcaaca
    34741 cctcttaaag ttctctcaag ctcttgtgct gtcgtccatt tttatcaaag ttttcaggac
    34801 gcaaccatat ttccaatcga gctttgactt gaggccagtc cttatcaatc atagacaacc
    34861 aatccgtatc tcttgtacgc cccttataaa ccactgcctg acggaaggtt ccttcataaa
    34921 taaatcccaa acgttccgct gctcgtctgg atggcaggtt aagagcatcg catttccact
    34981 catagcgacg atagttaagc tcctcaaaga catagcaagc caagagatac tgggcttctg
    35041 ttcctatccg tgtccccctg agctctggag aaaaagtgac agctcccact tctattactc
    35101 ggttattctg atcaattcgc atgagggaaa aagttcccaa agccttacca gttgccttgt
    35161 ctatgattgc ataataaaaa cggtccttac gagccaacat ctgatttaaa aggctgacca
    35221 gttcctccat gtctgctact gactcctgaa agaggtaggt ccacatctcc cgaggcgtat
    35281 cagggccata aacagctaat aaatcctccg catgcttttc cactgaaaga gcctctatcc
    35341 tagcataacg cccttctaag aaatcaaaag aaggcaattc acctggagta taagcttcca
    35401 ttgactcccc aatcatttga ccatattcat ttactggcat cttattctcc ttatttcact
    35461 tttcaaactt tatagttgcc catagtatat catactttca taagaagatt caaaaaatcc
    35521 tccagattct actctgaagg actcctatct tatttcaaaa caatattaac gagtttaact
    35581 ggctcaaaca gtttaggaaa ctgtccgaga tttgaaacca gcaaataaat tggttatttc
    35641 acaacaatat taaccaattt attcggtact gcaatcactt tcacgatttc cttaccgtca
    35701 atttctgctt tgactttttc atccgctaga gaaatttctt gcaattcttc acgtgatagg
    35761 tctttagcga ccatgagttt ggcacggact ttacctttga tttggacaac gatttcgatt
    35821 tcgtcttcaa ccagtttact ttcgtcccaa gttggccaag ctacataaga gattgactca
    35881 cctgtttctg cgactgtttg ccagagttct tctgccaagt gaggtgcaaa tggtgcaatc
    35941 aattgaataa agcctttggc atagtcaaca taaagcttat cttccttgtt agcagcattg
    36001 acaaagacca taagttgggc aatagctgtg ttgaatttga gagactcaat ttgctcagta
    36061 acagctttga ctgtttcgtt gtaagccttg tcaagagcac cattgttttc cgcaaggatt
    36121 tctttacttg taatcaaacg gtaaactcgg tcaaggaact tacggcttcc ttccaaacct
    36181 tcttctgacc aagcaatcga agcattgagt ggtcccataa acatttcata aacacgaagg
    36241 gtatcggcac cgtattgttc caccacatca tctgggttaa caacgttctt gagcgattta
    36301 gacatcttgg ctggcgcttg ctccaactct tcccctgttt ctatatgaaa gaaggaacca
    36361 tcacgttttt caaccttgtc ggttgccaca agagcaccac ggtggtcacg gtagcttgtt
    36421 cccaaaatca tcccttggtt aaagagtttt tggaatggtt ccttagtcgg aacaacaccg
    36481 aggtcataga ggaatttatg ccagaaacga gcataaagca agtgaagtac agcatgttcc
    36541 gcaccaccca cgtagatatc tactggcaac cattgtttga ggaggtcctc atcagccaat
    36601 ttctcagtat tgtgcgggtc aatatagcgg aggtagtacc agcttgaacc agcccattgt
    36661 ggcatggtgt tagtttcacg acgacctttg acaccatctt cacgagtcac ttcaagccaa
    36721 tctgtcaagt tagctagtgg actttcacca gtacctgaag gacggatatc cttggttaca
    36781 ggcaagacaa gcggcaattc agtttcagga acagctgttg aagttccatc ttcccaatga
    36841 atgattggaa ttggctcacc ccagtaacgt tgacggctaa agagccagtc gcggaggcgg
    36901 taggtaacct tctcctgacc acagcctttt tcttccaagc aagccacaat cttggcaata
    36961 gcgtcttctt tgttgagtcc atctaggaag tctgaattga catgaagacc atcctctgtg
    37021 taggcagctt ctgctacatt tccaccttca agtacttcta cgattggaag gtcaaattgt
    37081 ttggcaaatt cccagtcacg ttggtcatgg gcaggtacag ccataacggc acctgtacca
    37141 tagctagcaa gaacgtaatc cgcaatccag attggaattt ccttaccatt gacaggattg
    37201 atggcataag caccagtcca aacccctgtt ttttctttgg caaggtctgt acgagccaag
    37261 tctgatttca gactggcttg gtgtttgtag tctgctactg cttctgcttg ctctgtgctt
    37321 gtgattgcat ctactagttc atgctcagga gccaaaacgg tgaaagtcgc accgaaaaga
    37381 gtatcaggac gagtggtaaa gacggtgaat tccttgtctg ttcccttaac tttaaaagtt
    37441 acattagcac cagttgattt accaatccag ttgcgttgca tgtccttgat agactctggc
    37501 cagtcaagct cgtctaagtc attgagcaag cgctccgcat aggccgtaat tttaagcatc
    37561 cattgacgca tcggcttacg gacaactgga tagcctccac gctcagaagt tccatcagga
    37621 agcacttctt cattggcaat ggctgttccc aactcttcca cccagtttac tggcacttcc
    37681 gcttcatagg ccaagccttt ttcgtaaagc ttagtgaaaa tccactgagt ccacttgtag
    37741 tagtttggat ctgttgtgtt gacttcacga tcccagtcat aagaaaatcc aagcgcattg
    37801 atttggcgtt tgaagttggc aatattttcc gctgtaaatt ctgctgggtc attacctgta
    37861 tccatagcgt attgctctgc aggcaaacca aaagcatccc accccattgg gtgaagaaca
    37921 ttgtagcctt gcgcacgttt gtaacggctg aggatatcgg ttgcggtata accttctggg
    37981 tgtcctacgt gcagacccgc tccagacgga taagggaaca tatcaagcgc ataaaacttc
    38041 ggttttgatg catctgttcc tgtcttaaag gtatgatgtt ctgcccagta gccctgccac
    38101 ttaggctcaa tttctttatg attgtaaaaa ctcatggtct ctctccaatt ttgtgatgtt
    38161 actattatac catttttgag ggaatttgaa atgtgtttaa agaaaaaact gtatactgta
    38221 tctcattaat tttgatgact atgaattgct ctatctccca ctttttatcc cattgttatg
    38281 cagtaaatca aggagtaagt caagaaactt atctcgtata gcacaaaata cttattttag
    38341 accgaagata aaactggaat gctaattaat gtattcacaa taaatagccg acaacctatg
    38401 tcgctttttg atttatgaag aacgtatagt agactgaatc tgaaatagta cgaaacaatt
    38461 gctaaaacat ttatagaaat taattttact ttcccaatcg atttgttctc atcctatttc
    38521 aatcttctat agaattcaat acggggatca ataaaagact accatttgga aaacagtagt
    38581 ccttattgtt tattttgaat ttacataggc atctacagcg ataatagctt gagcaacatc
    38641 tgaaggcgaa atcttaaacg gcatctgatg aattgtctca ccctccatag ttgcttgttt
    38701 accaactttt attaaatcat catatccaac ttgatccaaa tgcatttctt ttagagttgt
    38761 tggcatacca atttttttgt aaaactcaat atacttatca agttcttctt taggtctatt
    38821 ttccaataat agttgtacta aagttccata agctactttt tcaccatgtg ttaaatgatg
    38881 aatgtcacct gtcaatgcag taaaaccatt atgaattgca tgcgccgcag ctaatcctcc
    38941 actttcaaaa cctagaccac tcaataaagt attagcttca acaatatttt ctaatgctgg
    39001 tgtcaccact ttagcttcac aagctgccat agcctgtaaa ccatctgcaa acagcgtttc
    39061 ttcacatttc ttcgcaattg caactccagc caatgtttgc tgttgtccca acatagtttt
    39121 tccatttgcc tgcataaccg cacgcgcctc aacccaagtt gctaaaccat ctgcaatacc
    39181 agacgctaat aaacgcttag gggcttgtga aataactttt gtatcaacca aaactaaatc
    39241 tggattttta gaataaaata gataatgatc aaatgcacct tcatctgtat aaataacaga
    39301 taaagcagat acaggtgcgt cggtcgatgc aattgttgga gcaataataa caggcttttc
    39361 aatcaaatct gcaatagctt ttgcgctatc aatcgtcttt cccccaccaa gaccgataat
    39421 actatcacaa ttttctttct cagccaaggc aacaactcga ttgatttcat tgtcagaagc
    39481 ttcaccatta aatagcgcca gaacaatatg gaaaccatac ctatgtaggt aatcttcaaa
    39541 tcgttttcca acaatatcat aaaccaactg atcgcataat agaatagggt aatttcccaa
    39601 atccaaaatt gatttggcat tttcaaacaa ggcattttcc ccctgaatat atctagaagg
    39661 actagcaaaa attctcatat atatttcctc tctatctaaa tggaacgact attttgagta
    39721 acaaaccaat cgtcagaaaa atcatcaacc gccttttgga tagatggcat ggcgaaagct
    39781 gattcaaaaa catctgctcc tgctgtaaca gcatgcgcac ctgcagctaa agcattattt
    39841 acttgtgcta catttttaaa ggatgcagct aaaatcttac taggagagtt ctgtctatca
    39901 atagcaagag ctaattgacg aatgacagaa tttgaatcaa tgttcagatt ttccattcta
    39961 ttataatatg gagctaggta atcagctcct gcttcgatag ctaataatcc ctgaataact
    40021 gtataaatag ctgttgcagt gatatggtag ccctcttttt ttagcacctt tattgcacgt
    40081 aatccagctg gagtaacagg tactttgata aatatatcat ctcctgcttg tcttcgaatt
    40141 tcatgagcat cctttaagat gccttcaaaa tcttgagaaa tcacctgaac atgaatagag
    40201 ggtgtagagc caatcaattc tcttacatct ttgattcgtt caaaaaaatt aatagaaccc
    40261 tctctttttg caatagtggg atttgaagtt accccagcta gcggcaaaat ttcagaccac
    40321 tttttaatct catctaaatt taatgtgtca agcataaatt ccataaaaag aacctcttta
    40381 ttttacaaag tatgctcagt acgtcctata atgtcatctt gggttgcctt agaaagaaca
    40441 ttgaagaatg cagagtatcc tgcaacacga acaattaagt ctctgtgttt ttcaggatgt
    40501 ttctgagcgt caatcagcgt ctctctggaa acaacattgt attgaatatg gtacccatgt
    40561 aaacgattaa agaatgttcg taacaaagca attagtttta atttatcttc ttctttggct
    40621 aacgtttgag gatttacttt ctgatttaag agaaccccac ctacgatttc atctgttggt
    40681 aattttgaaa cagattttaa aacagatgta gggccgtgtt gatccatatt atgtgatggt
    40741 gaacaaccct ctgctaacgg tgtacccgcg ttgcgtccat ctggagttgc taatgttcca
    40801 cgtccctgcc ctacgttggc tgagatagaa gatgttcctg aataacgaat tcctccaata
    40861 ggccctcttc cataacgtgt attaggatat ttagcaattt catcaacata aatgtcataa
    40921 gcagcagtaa ccaatttgtc agcataatca tcatcattac catacttagg tgcatcatga
    40981 atcaacattt cttgaatgac cttaccttct tctccggcat aatctgtttc cagtgcatgc
    41041 caaagttgac ttgggcttat acgttcttcc tcaaacacca attttttaat tgcagctaac
    41101 gaatccgaca aatttgcaat tccaacttgc aatcctgata tataatcata tactgctcca
    41161 ccttctttaa ggtgttttcc acgaccaata caatcatcag tcaatgctga acatagaata
    41221 tcaggaactt ctcgttccaa tgataaatca atagaatttt caacaataac actcattcgt
    41281 gtcaaatatc ttagtgtttt atcccaagca ttttctaatt cagaaaagtt cttcatatcc
    41341 ttaaaatgac caaagcttgg tgcaaaccgt ttacccgaag ccggatcaat tccatcattc
    41401 atcgtgataa gtagaacctt agggaagttc atataactca tacctgtgca acgatagccc
    41461 catttccctg gaactgccgt ttcaacacat ccaatggcac tgtaatcata agcatcatct
    41521 tccaatactc cttttgcaat aaaagaagga ataataatct catcattatt aaatgcaggc
    41581 ataccaaaac caagtttcat cacttcaata cactcattca tgaaacgagc atctaaacct
    41641 gcatggtaac gtacagttag attaggttgc ggtagatggg tttgtgcaac tgattttaat
    41701 accaaataag ataatgggtt aacagcatcc ttcttatctc gagtctgtcc accaattgta
    41761 acattttgat ataaaggact tcctgctgaa gaaaatgtat gtgattgact gcgaacctta
    41821 ttaattgtaa ttgtcttaat ccaaagattt gtcagacgtt caacaatgct atcttctgtt
    41881 tctttaccac tttctaaatc agccttcata tatggataca tatattgatc aaaacggcca
    41941 tatgaaagag agtggccatt agattcaatt tgtaaaatac attgaataaa ccaaactgat
    42001 tgaatagctt ctgcaaaagt agttgccggt tcatatggga ctctagagca aatatctgca
    42061 atctcaagta attctttctt acgtttagga tttgcatttt cggctaaact tttagcaaga
    42121 gcaacaaagc gctttgcata tactttaata gcatcgatta cgataaatat agagtcgtaa
    42181 aaatgatatt tatcaatact tgctggatct gttaaatcta gagctacttt tgctttacga
    42241 gcccgctctt caaaacctct taaaccaaat tgcaaaagtt tctgatagtt aactgctaag
    42301 tgagcatctc cagaattcat cttaccttcc ataccgaaga atcctgtttc catataaact
    42361 gacacttctt caggtaataa ggcaccagct ctagcacgta aattattatt ttcccaaaac
    42421 ggagcaatac ttctaagttg ttcttttgtt tcttctgtaa tatagaaaac atctccatca
    42481 cgcttttcaa aaagatccaa ctcattgaga acaaattcta gcgtatattc cggaaaaata
    42541 ggagcatctt tattggaaga agcttgattt cccgcaatca tagattcttc ttcaatatag
    42601 atagacatat tttccaaaat ttctttcagc atatatgcac gttttaggac attaggttgt
    42661 tccttgtatc gttcataggc gcgtgttgct agaactgctc tctcagcatc aatataaggt
    42721 tttttattta aaacatcttc tcgatatttg ttcatccttt cagtaaggct gccaaaatat
    42781 tctgtcttga ttgttgttct tgctacttct gtatttacca tcgtaagcac ctttctttcg
    42841 aaaatatttt tatttctttc gaaaatataa taccgatttt tatagaaatt ttcaagcttt
    42901 taactagaaa aattttaact ctctaatttt tagcacaaat gtgtgagttt aacagtaaca
    42961 cacaaatacc tctaagattg tttgatttca ttttggtaag ctaaacgatc ttgtatctta
    43021 aagaatggaa agtaaaccac tgtagatatc accaatacta ataactgagt cacaacacct
    43081 tgccatccac ccaccaaaaa tcctgataga atagctggtg tactccaagg caatgttacc
    43141 cctgagaatg gctgcatgaa acctgttgca atagctccat atactatcac agctgcaagt
    43201 acaggaacaa gaatgaaagg tacaaacata actggattca tgacaatcgg aaatccaaat
    43261 acaactggct catttacgtt aaatattgct ggaaaagctg caacttttcc taaggcttgg
    43321 tattgttttg attttgctgc aaaaagcatg gcaactacaa gaccaaacgt aatccctgaa
    43381 cctgatagaa ttaaaaatga atctaaaaat tgttgagtaa caatatgtgc accattttct
    43441 aatgatagat tagcagaggc taacatagct ttattagcgt caagattaga taaaagcaga
    43501 gctgtcacta ctccatttac taccgattgc ccatgaacac caaaccacca caaaaatgat
    43561 ataaagaatg caattccaat agcaccatac aaagatccag ttaaaccttg caacggaact
    43621 tgaatagcag aataaatcat ttctatgaat gttccgccat tagtcaatga cttcgctaaa
    43681 atatatacaa tcatagaaga taagaaaatt acaaatgctg gaatcattgc ttcaaactgt
    43741 ttggcaatag cttgtggaac ttgttctggc atcttaataa caatttttct ctttataaag
    43801 aaggtataaa tacttcctac taccaaacct ataatgatag caccgataat tccttggcct
    43861 ccaaaccaaa ctttactaat agcgtcccca atcgcctcac cttgtttagg gatataagat
    43921 gatcttagca aaataaagaa tgcagataca gatagaactc cagctggtaa agcctctact
    43981 ccgctattct tagcataaga ataggcaatt gaaaaacaag aaattagacc cataatagca
    44041 aaagttcctg aatatacttg cataaacggc tctgtccaat tagctccaaa aacactagca
    44101 atgctcttat ttaatccttc gaacggcaat tgtcccataa tcaagaacaa actgccaact
    44161 actgtcaatg gcaaaattgc taacatccca tcttttagag ctataatgcc acgcatattc
    44221 acaaacttca tcatcggtgc aatgattttc tgaacatcca tctttgacat aataaatctc
    44281 cttttcttac ccactaatca aagatagggc caaatctaat acttttttcc catctaacat
    44341 accatagtcc atcatcggaa taacagctat cggaacatca cacttatcac aaatttcttt
    44401 tgatttatct aatgtataag caacttgtgg acccaatagt gcaacatcta tatttggcgc
    44461 ataatccgct aatttagact gagaaaacgc ctctatttct gcctcaactc cactagattg
    44521 cgctgcaatt ttcatattat ttacaagcat accagtagaa aaacctgctg cacaaaacaa
    44581 accaatcttc accattatgt tttcctcctc tatgttaata acaatgataa tactctagta
    44641 ttatttttta tgaagttctt ttctcaaact aataatttct ttgattaaat taatctccgt
    44701 catactagtc atgagatgat cttgtgaatg aacaaagaga gctgtaattt ctgtctttgt
    44761 accagacgct tcctgtgcca agaattttgt ttgtagatta tgagcttcta ataaggctgc
    44821 atcagctaac tggatttctt cttcacaccg ttcacatgta ccatttttta tgtaatctaa
    44881 cgctttataa atatgttgtt tcgcatcacc agcatataaa attaaaccca tgataatttg
    44941 atctggaaca ataatttcca taaattcctc ctcatttcac tatgtaaaaa gcttttttca
    45001 tttgaaattt taaaattttc ttttgtaact atagaataca actacataat aaagttgtca
    45061 atccaaaaac aacagataaa ctatttttgt ttatataagc acaaatgtgc aatcaactaa
    45121 aaagaaaaac gataaactga atcagtctat cattttcact cacctagaat ctctctaaaa
    45181 gtcaaatccc catcttcttc caaaactttt aaaattgtat ttttgtctgt aatcaaatga
    45241 tttactaaat tagcacgcaa gacagaaaga atcgaagata ctttcgtatc accgtaagca
    45301 acagctaaac tttgaggaat attttttaaa tcttccaaag agattgctat cgttctttcc
    45361 tgtaagtttt catagacttc tttacctttt gaatcaaaaa atcgacaaca aatttctcct
    45421 acagttttaa ctttggtcaa ttctttaaag tcatcctctg taagcatgtc taaccattga
    45481 tgctttcctt tattgctaaa atcaccaatt ccgactacag ctatatctaa atctttccaa
    45541 ctatttttca aattttcaaa atatcttgat tgcaaaatac catctgctaa caatttattt
    45601 tcttgcacaa tcgttgcatt cataaatgta cactctccat gaaattttct agacatttca
    45661 taaatcagtg tattcacatg gtatttagcg tgtatgtgac taggaccacc tgctagagga
    45721 tagaagtgaa catttcggac acttttactg tgaattaaat ctactaaatt acttaaactt
    45781 ttcccccaag aaaagccaat tttcatatta tcatcaatta gattcctaag gacacctgct
    45841 gcaacttgag aaattctttc agataaaatt gttggattat catcaaattc atttggaata
    45901 atttctaaac tttccagacc atatttttct tttacataat tttccaactt aaacatattg
    45961 gtatcaaaat tctctatttc aattttaaca attcctgcat tccttgcttc tgttaacatt
    46021 ctactaatag aggttctata aattcctaat tttgctgcta tttgtgactg atttaagttt
    46081 tcaatataat acagataagc aattttagag agcagtttat tcctatcttg attcatacat
    46141 ttaacctctt acgaaactac cttaaccatt atcccagcat tttctaatgt agctatattt
    46201 tgtttagaaa gtttttcgtc tgttattact tcatagactt gacttaaagc aaatcttctt
    46261 actgtacccc ttttatcaaa tttacttgag tcagttagta caatgacttt atccgacgct
    46321 gctgaaatat attgaactac ctcactgcgc attaaatctt ttcctgtaaa gcccatctct
    46381 ttatcgtaac catctgtccc aacaaaagct tgatgcacat gaaaagtctg tatcatttct
    46441 tttaataaag gtcccacagt aacctgtgaa tccttctgaa actctccacc aagaacaata
    46501 atacgacatg aatcataagc tctcacaaaa tttgctataa aaaatgaatt tgttacaatc
    46561 gtaacatttc ttttttgctt gcaaatttcc tcagcaagta aagcacaggt cgatccagat
    46621 tctatcatta ttgtttcatt atctgacacc aattttactg cttcctgaac aatttttctc
    46681 ttaatttcat agttaattga caaacgtaca tttaagtcat ctccactatt taatacagca
    46741 tatccatgct ctctgtgtaa taaacctttt gactctaatt tatctaaatc ttttctaatc
    46801 gttactttcg atacatttaa tttttccgat aatgtattaa cgtcgatctt ttcatattct
    46861 gatactaatt taataatttg ttccaatctt ttcattttac acctccgttt tattctacca
    46921 aaataaaaag caaaaaacaa caaattaaac tttcgttcgt aattgttttt ctttcgtttt
    46981 tgtgatagga tagacttatg aagaggagga actcttatgg aaatatctaa aggaattatt
    47041 tttaatattc aacacttttc aattcatgac ggcccgggta ttcgtacaac tgttttttta
    47101 aaaggatgtc ctctgcgctg tccatggtgt tctaatcctg aatctcaaag aatgaaacct
    47161 gaaaaaatga aagatgctca acgagagaaa ttcaccttag tcggtgaaga aaagactgta
    47221 gaagaaatta ttacagaggt attaaaagac aaagaatttt acgaagaatc cggtggaggt
    47281 ttaactttat caggaggtga aatatttgct cagtttgaat ttgctaaagc catcttaaaa
    47341 tcagctaaag aacatcacat acacactgcc attgaaacta ctgcctttgt tgatcatgaa
    47401 aaatttattg atttaattca atatgtggat tttatctaca cagacctaaa acattataat
    47461 tctataaaac ataaaaaagt gactggggtt tttaatcaaa tgattattaa aaacattcat
    47521 tatgcttttt ctcaaaataa aactatcgtt ttaagaatcc cagttattcc taattttaac
    47581 aatagtttag aggatgcaga aaaattcgct actctattta actcattaaa tatcgaccaa
    47641 gttcaactac tcccttttca tcaatttggt gaaaacaaat atcgtttatt aaatcggaaa
    47701 tatgaaatgg atggaatcaa cgcacttcat cctgaagatc ttattgatta tcaaaaggta
    47761 tttctgaacc accatattaa ttgttatttc tagtttattt ccttgaaatg ctctagctat
    47821 ttgcagataa caagcatcta tataaggtta tcaaagaaga cttccccatg actctaaatg
    47881 aatatatctt acaatatcgc ctgaaacaag ctatagataa gatggctgaa tctcccaact
    47941 cccctttaag cgctatctct gaccaagttg gattttcaga ctataaatat tttgccaaag
    48001 tatttaaaaa gtatctccat atttccccaa agaaattgaa atcactcgga agaatagtaa
    48061 aataggctat tcttcttttt gtagagaatt ttactctaat atagtgaatt gaaataagat
    48121 gtgaacatct ctatca
//
LOCUS       DAVMCG010000012        45667 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVMCG010000012 DAVMCG010000000
VERSION     DAVMCG010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.012"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(224..2875)
                     /gene="adhE"
                     /locus_tag="VYP66_000817"
                     /gene_synonym="adhC"
     CDS             complement(224..2875)
                     /gene="adhE"
                     /locus_tag="VYP66_000817"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1850403.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(3175..3585)
                     /locus_tag="VYP66_000818"
     CDS             complement(3175..3585)
                     /locus_tag="VYP66_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850404.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            complement(3587..4015)
                     /locus_tag="VYP66_000819"
     CDS             complement(3587..4015)
                     /locus_tag="VYP66_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1850405.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            complement(4062..4361)
                     /gene="yajC"
                     /locus_tag="VYP66_000820"
     CDS             complement(4062..4361)
                     /gene="yajC"
                     /locus_tag="VYP66_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1850406.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            complement(4478..6454)
                     /gene="tkt"
                     /locus_tag="VYP66_000821"
     CDS             complement(4478..6454)
                     /gene="tkt"
                     /locus_tag="VYP66_000821"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1850407.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            complement(6567..7658)
                     /gene="ulaG"
                     /locus_tag="VYP66_000822"
     CDS             complement(6567..7658)
                     /gene="ulaG"
                     /locus_tag="VYP66_000822"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1850408.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            complement(7770..9443)
                     /locus_tag="VYP66_000823"
     CDS             complement(7770..9443)
                     /locus_tag="VYP66_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1850409.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            complement(9622..10326)
                     /locus_tag="VYP66_000824"
     CDS             complement(9622..10326)
                     /locus_tag="VYP66_000824"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1850410.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            complement(10328..11191)
                     /locus_tag="VYP66_000825"
     CDS             complement(10328..11191)
                     /locus_tag="VYP66_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1850411.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            complement(11195..11860)
                     /locus_tag="VYP66_000826"
     CDS             complement(11195..11860)
                     /locus_tag="VYP66_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1850412.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            complement(11877..12362)
                     /locus_tag="VYP66_000827"
     CDS             complement(11877..12362)
                     /locus_tag="VYP66_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1850413.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            complement(12439..12720)
                     /locus_tag="VYP66_000828"
     CDS             complement(12439..12720)
                     /locus_tag="VYP66_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1850414.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            complement(12743..14200)
                     /locus_tag="VYP66_000829"
                     /pseudo
     CDS             complement(12743..14200)
                     /locus_tag="VYP66_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
     gene            complement(14331..14954)
                     /locus_tag="VYP66_000830"
     CDS             complement(14331..14954)
                     /locus_tag="VYP66_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1850415.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQTKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            complement(15005..15991)
                     /locus_tag="VYP66_000831"
     CDS             complement(15005..15991)
                     /locus_tag="VYP66_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1850416.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            complement(16010..16834)
                     /locus_tag="VYP66_000832"
     CDS             complement(16010..16834)
                     /locus_tag="VYP66_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1850417.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            complement(16809..17180)
                     /gene="rnpA"
                     /locus_tag="VYP66_000833"
     CDS             complement(16809..17180)
                     /gene="rnpA"
                     /locus_tag="VYP66_000833"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1850418.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            complement(17329..18519)
                     /locus_tag="VYP66_000834"
     CDS             complement(17329..18519)
                     /locus_tag="VYP66_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1850419.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            complement(18570..19523)
                     /locus_tag="VYP66_000835"
     CDS             complement(18570..19523)
                     /locus_tag="VYP66_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1850420.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYTHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            complement(19584..20178)
                     /locus_tag="VYP66_000836"
                     /pseudo
     CDS             complement(19584..20178)
                     /locus_tag="VYP66_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(20315..20728)
                     /locus_tag="VYP66_000837"
     CDS             complement(20315..20728)
                     /locus_tag="VYP66_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1850421.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            complement(20706..21167)
                     /locus_tag="VYP66_000838"
     CDS             complement(20706..21167)
                     /locus_tag="VYP66_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1850422.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            complement(21130..21390)
                     /locus_tag="VYP66_000839"
     CDS             complement(21130..21390)
                     /locus_tag="VYP66_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850423.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(21395..21823)
                     /locus_tag="VYP66_000840"
     CDS             complement(21395..21823)
                     /locus_tag="VYP66_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1850424.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(21792..22118)
                     /gene="comGC"
                     /locus_tag="VYP66_000841"
     CDS             complement(21792..22118)
                     /gene="comGC"
                     /locus_tag="VYP66_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1850425.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            complement(22120..23136)
                     /locus_tag="VYP66_000842"
     CDS             complement(22120..23136)
                     /locus_tag="VYP66_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1850426.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(23084..24025)
                     /locus_tag="VYP66_000843"
     CDS             complement(23084..24025)
                     /locus_tag="VYP66_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1850427.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(24101..24466)
                     /locus_tag="VYP66_000844"
     CDS             complement(24101..24466)
                     /locus_tag="VYP66_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1850428.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(24617..25675)
                     /locus_tag="VYP66_000845"
     CDS             complement(24617..25675)
                     /locus_tag="VYP66_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1850429.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(25838..26989)
                     /gene="nagA"
                     /locus_tag="VYP66_000846"
     CDS             complement(25838..26989)
                     /gene="nagA"
                     /locus_tag="VYP66_000846"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1850430.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(27142..28959)
                     /locus_tag="VYP66_000847"
     CDS             complement(27142..28959)
                     /locus_tag="VYP66_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1850431.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(29060..30202)
                     /gene="tgt"
                     /locus_tag="VYP66_000848"
     CDS             complement(29060..30202)
                     /gene="tgt"
                     /locus_tag="VYP66_000848"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1850432.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            30332..31189
                     /locus_tag="VYP66_000849"
     CDS             30332..31189
                     /locus_tag="VYP66_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1850433.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFILDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(31217..31861)
                     /gene="pcp"
                     /locus_tag="VYP66_000850"
     CDS             complement(31217..31861)
                     /gene="pcp"
                     /locus_tag="VYP66_000850"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1850434.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(31936..32337)
                     /locus_tag="VYP66_000851"
     CDS             complement(31936..32337)
                     /locus_tag="VYP66_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEV1850435.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKIHLKVDSNLANPF"
     gene            complement(32348..32773)
                     /locus_tag="VYP66_000852"
     CDS             complement(32348..32773)
                     /locus_tag="VYP66_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1850436.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAIQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(33096..34208)
                     /locus_tag="VYP66_000853"
     CDS             complement(33096..34208)
                     /locus_tag="VYP66_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1850437.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEVTKTVIASEEVAPST
                     GTSVPEEQTTETTRPVEEATPQETTPAEKQETQASPQAASAVEVTTTSSEAKEVASSN
                     GATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAAFKEEIANLFG
                     ITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGISYIIWKQRFY
                     APFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(34374..34994)
                     /locus_tag="VYP66_000854"
     CDS             complement(34374..34994)
                     /locus_tag="VYP66_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1850438.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(34998..36278)
                     /locus_tag="VYP66_000855"
     CDS             complement(34998..36278)
                     /locus_tag="VYP66_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1850439.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(36339..37823)
                     /locus_tag="VYP66_000856"
     CDS             complement(36339..37823)
                     /locus_tag="VYP66_000856"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1850440.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDTSYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTTELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(37899..39176)
                     /locus_tag="VYP66_000857"
     CDS             complement(37899..39176)
                     /locus_tag="VYP66_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1850441.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(39439..39687)
                     /locus_tag="VYP66_000858"
     CDS             complement(39439..39687)
                     /locus_tag="VYP66_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000967644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850442.1"
                     /translation="MLYWISVNYEITEDEDFETVKTRVISDFESYLKLLNGKFEESLK
                     KVIKSFTFSKLIGEKLCNGEDLKNLSKEIRHQIQDRNS"
     gene            39847..40323
                     /locus_tag="VYP66_000859"
     CDS             39847..40323
                     /locus_tag="VYP66_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850443.1"
                     /translation="MSRTYINIRLAYETKYWLECIQEEVQKKLDALINEQDIEELESI
                     ITNKLEKKDSLLGAVSITTFFKVSSSSVIEKAYNETKNYTTSEWREIARQMNLAKVKQ
                     NMEIGTLTPRLYLDNNIISELEKYQFLFKSDDMIRQVRMSYVIKMVAFAYYKKLFA"
     gene            40494..41048
                     /locus_tag="VYP66_000860"
     CDS             40494..41048
                     /locus_tag="VYP66_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850444.1"
                     /translation="MPKLLETEKYSLDSIIDGGKLRMISKFCPDLHGLRYEFKTSDSI
                     TKEYCKKIRQALRDSDPEGKSGKKCMMRYTIDILNVWNTLCRTRDFITGSLKADDVID
                     GKTGIYFFDVNTSNVITDDVIENVKINHKSLVRNVDEENIESISKEIPKGTDMYYYVL
                     YRLGLNRIKYNYLVKALAGAIQKD"
     gene            41704..41826
                     /locus_tag="VYP66_000861"
                     /pseudo
     CDS             41704..41826
                     /locus_tag="VYP66_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
     gene            41830..42963
                     /locus_tag="VYP66_000862"
     CDS             41830..42963
                     /locus_tag="VYP66_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1850445.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYMTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            43004..43441
                     /locus_tag="VYP66_000863"
     CDS             43004..43441
                     /locus_tag="VYP66_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1850446.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVTTDEE
                     KAVAYLHDVIEDTTLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKTNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRTKKKS"
     gene            43649..43885
                     /locus_tag="VYP66_000864"
     CDS             43649..43885
                     /locus_tag="VYP66_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1850447.1"
                     /translation="MNNVVTTLISVQFSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKTISHEEMMRRYG"
     gene            43878..44609
                     /locus_tag="VYP66_000865"
     CDS             43878..44609
                     /locus_tag="VYP66_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1850448.1"
                     /translation="MAKIYAISDIHGYLDEFIDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEIYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GMLWKELTSSKIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYLI
                     DGDVTNSKTIPVLCYDTITQKYHFL"
     gene            complement(44720..44803)
                     /locus_tag="VYP66_000866"
     tRNA            complement(44720..44803)
                     /locus_tag="VYP66_000866"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44767..44769),aa:Leu,seq:caa)
     gene            complement(44813..44884)
                     /locus_tag="VYP66_000867"
     tRNA            complement(44813..44884)
                     /locus_tag="VYP66_000867"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44850..44852),aa:Gln,seq:ttg)
     gene            complement(44898..44970)
                     /locus_tag="VYP66_000868"
     tRNA            complement(44898..44970)
                     /locus_tag="VYP66_000868"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(44935..44937),aa:His,seq:gtg)
     gene            complement(44985..45055)
                     /locus_tag="VYP66_000869"
     tRNA            complement(44985..45055)
                     /locus_tag="VYP66_000869"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45021..45023),aa:Trp,seq:cca)
     gene            complement(45060..45140)
                     /locus_tag="VYP66_000870"
     tRNA            complement(45060..45140)
                     /locus_tag="VYP66_000870"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45104..45106),aa:Tyr,seq:gta)
     gene            complement(45153..45225)
                     /locus_tag="VYP66_000871"
     tRNA            complement(45153..45225)
                     /locus_tag="VYP66_000871"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45190..45192),aa:Phe,seq:gaa)
     gene            complement(45229..45302)
                     /locus_tag="VYP66_000872"
     tRNA            complement(45229..45302)
                     /locus_tag="VYP66_000872"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45266..45268),aa:Met,seq:cat)
     gene            complement(45313..45402)
                     /locus_tag="VYP66_000873"
     tRNA            complement(45313..45402)
                     /locus_tag="VYP66_000873"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45364..45366),aa:Ser,seq:tga)
     gene            complement(45485..45558)
                     /locus_tag="VYP66_000874"
     tRNA            complement(45485..45558)
                     /locus_tag="VYP66_000874"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45522..45524),aa:Ile,seq:gat)
     gene            complement(45593..45663)
                     /locus_tag="VYP66_000875"
     tRNA            complement(45593..45663)
                     /locus_tag="VYP66_000875"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(45629..45631),aa:Gly,seq:tcc)
BASE COUNT        13848 a         9838 c         8118 g        13863 t
ORIGIN      
        1 ttctaacaat gttttagaag cagatgtgta ctactctagt ttcaatctat tatatatttt
       61 gtttctattc tagtttttca aaaagggcaa aaaggcctca atatcataaa aaggcatcct
      121 atcaggtgtt caaaaacctt gataggatgc cttttatcat agaaaaatta ctggatcttt
      181 ccctcaaatt gagtttttgt cttgcttcta gactgataaa caattattta cggcgtcctg
      241 gtctttcttt gtagccatag tatgcatctt cgatgatttc ttgcatatgg tctaccattg
      301 gaagacgtgg gttagctggt gaacattggt cttcataagc caggaaggct aattcacgag
      361 aatgttcttt ccattctttt tcgtcaattc cttggtctct aaaattcatt tggatcccaa
      421 tacgttcacc gagttcgtag acagcttttg cgtaagattc aaccccttct tctggagtag
      481 aagctggaag tccaagcatg cgtgcgatat cttggtattt ttcatctgca cggtagtagt
      541 tgtacttagg ccatgttgct gtcttagctg gacgtgtacc gttgtaacgg ataacgtatg
      601 gaagcaagat agcatttgta cgaccgtgga ttgtgtggaa ttgcgcacca atcttatggg
      661 ccattgagtg agaaatacct aggaaggcat tggcaaaggc cataccagcg attgttgaag
      721 cgttatgcat tttctcacgt gagtggaagt ctgcattctt aactgagctt tcgagatttt
      781 caaagaccaa tttaatggct tgaagtgcta aaccatcagt gtagtcacta gccatttgtg
      841 atacgtatgc ttctgtcgcg tgagtcaata cgtccatacc agtatcagca gcaacaaatc
      901 ctggaactgt caataccaaa gcaggatcta cgattgccac agttggtgtc aatgagtagt
      961 cagcgattgg gtatttacgg ttgtttgctt tatcagagat aacggcaaat ggtgttactt
     1021 cagatcctgt accagatgta gttggaatcg cgatgaattt agtcttctta ccaagcaatg
     1081 ggaacttgaa ggcacgttta cggatatcca tgaatttttg gacaaggtca cggaagtcca
     1141 cttctggttg ctcgtagaag agccacatta ctttggcagc atccattgga gacccaccac
     1201 cgagtgcgat gatggtatct ggtttgaagg cacgcataat ctcagtacca cggtttacag
     1261 ttgtgatatc tggatccggt tctacatccg caaagatttg gtaaacaacc ttattgcgac
     1321 gaaggtccag ttgttcgatg atacgatcaa ggaaaccaag ctctaccatg gcatggtcag
     1381 taacgatcat gacacgttca acgtcacgac atttttgaag gtattgaatt gaatcacgtt
     1441 caaagtatgt ttttgaagga agtttcatcc attgcatgtt atttctccgt cttccgactt
     1501 ttttgatatt caagaggtta atggcactaa cgttatcccc aactgagttg cgtccgtaag
     1561 aaccacatcc aagtgtcaat gatggcaaga aggcattgta aacgtccccg ataccaccaa
     1621 aagtagaagg tgagttacag ataacacgaa tagctttaac agctttacca aattctttag
     1681 tcaattcttc gtcagctgtg tggatagctg ctgagtgtcc aagaccgtta aattcaacca
     1741 tttgacgagc cttagtaata ccatcttcac ggctttcaga tttcaaaact gcaataactg
     1801 gtgacaattt ttcacgagtc aatggctcat tttcgccaac ttctttacat tctgcagcaa
     1861 gaatgtttgt tccttctgga actgtaaatc ctgcttgttc tgcaatccaa gttgctggtt
     1921 taccaacgat gtcagcgttc aattttgcac cagcacagtt tttgctgttt gctttgacgc
     1981 cgaagcagaa ctcttcaaga agagcttttt cttttttgtt tacaaagtaa gtgtggtaag
     2041 atttgaactc tgctacaaat tcatcataaa tttctttatc aatgataact gcttgttcag
     2101 atgcacagac cataccgtta tcaaatgatt tagacatgac gatatcgtgt gctgcttgac
     2161 gaatgtttgc tgatttttca acataagctg gaacgtttcc ggcacctacc ccaagagctg
     2221 gtttaccaca tgaataagcc gccttaacca tggcattacc acctgttgca aggattgtcg
     2281 caacaccttc gtggttcata agggcacttg ttgcttccat agatggttga gtaatccatt
     2341 gcacacagtt ttcaggagca ccagctgcga tagctgcatc gcggacgata cgagctgcat
     2401 gagcagatga ttcttgtgct gatggatgga aggcaaagac gattgggtta cgtgtcttca
     2461 atgaaatcaa tgatttgaag attgctgttg atgttgggtt tgttgttgga gtaataccac
     2521 aaacaacacc aactggttca gcaataagag tcaatcctgt tacatcgtct tcttcgataa
     2581 cgccaactgt cttagtgtga cgcatgttgt ttactacgtg ttcacaggca aacaagttct
     2641 tagttgcttt atcttcaaat acaccacgtc ctgtttcttc aaaggcatgt aaagccaatt
     2701 ctccgtgggc atccaaagct gctactgatg ctttggcaac gatgtagtca acttgctctt
     2761 gatccaattt acgcatttct tcaagggcaa ctagagcttt ttgaaccaac tcatctacgt
     2821 gtttttcagc aacgagtttc ttttcctctg gtgtcacagt ttttttatca gccatatttt
     2881 cctccatagc tttcaaggat cgatatcctt tgttaatttt ttcacaagtt tattataacg
     2941 tattatttca actttgtaaa cagtttcata aacatttcac aaagaatttt taaactcttg
     3001 tgaaactttt ctcattttct tttcttatca ggttttatct ttgaagtttg tgaaatttat
     3061 ttcaaatatt ttttatttca caaacttgct tggaagaggg atttggaaag aaagggattt
     3121 acaggtaagc gcttaccttg taattctaat aatacctcct ttgataagga ggctttattt
     3181 ttgttgaaaa acgccttgtt taaaagttcc ttcataaacg acttcttgtt ctgttgttag
     3241 tttccctttt ccttcagcct gaccatttac aaaatcacct tcgtaggtcc agccttcttt
     3301 agattgaaag gtaccttttc cgttgaaggc tccattgttg aagccacctg tatattggtc
     3361 tccattttgg aaggtaatgg taccttgacc attcatttta ccacggacaa gactgccatc
     3421 ataaacaatc gttccattat cgagttttaa gacacctttt cctggaatat ttagaaaaaa
     3481 gacgagtaca gcacagaaaa caatggtaac tactgccaaa agctctaatc gtggacgagt
     3541 cagatagaca cgatactttt cgtaaaaatt cgtaagattt tccaccttaa ctctcctttt
     3601 ctaaacgttc taaccaagct tgacagccct cttgaacacg tcgataggtt tcttcaaaat
     3661 ctcctgtata ccaagggtct ggaacacttt cagatgaaaa tgagtaaatc ttatcttgac
     3721 agtctactgg acacatctga cgtaagtcag aaatatttga agcgtccatt ccgataatat
     3781 aatcaaaggc ttcaaaatct tccttactaa tctgaagcga tgtcttgttc ttgtcataag
     3841 gaatctcata ctcttgaaaa attccctgag tccccttatg aatcggattg ccatgttccc
     3901 aagaggaagt tgctcgactt tggatttcgt agttatctgt cattgatttc ataacaaact
     3961 cggccatagg gctacggcaa atatttccca gacagacaaa gactaatttt ttcatcccat
     4021 ttcctttctt ttatagaaaa acgggagttc gtgatcccgt cttatttttc aattgcgcct
     4081 tctagtgaag ctgtttcttt cagcggtaat actgtcttga tagcagctag ttcaaaagtc
     4141 aagtaaactc catctacgtc aagaactatt gttcccttct ccgtatctac ttcatcgact
     4201 gttccataaa gtccaccgat tgtaatcact tcatagcctt tttgtagttt atttaagctt
     4261 tccatacgct tttgagcttg tttcttttga gaacgttgca taaagaacat caaggccatc
     4321 atacctacaa gcatgattaa aaaagtaata tttggattca ttgttttctc ctttgtcttt
     4381 tacataggac tactatatca aatttcagct acttttacaa gattgtacct tacttttctg
     4441 gtaagaaaaa ccagagctta cgccctgatt tttaggatta tttcaagttt cgaacaactt
     4501 ttacaagatt ttctacagta aagccatatt ctgccaatac ttttggtgct ggggcagagg
     4561 ctccgaaggt atcaatacct agaacggcac catcgagacc aacatatttg taccagtttt
     4621 gacttgcacc catttcgact gcaacacgac ggcggactgc atttggaaga atctcttcct
     4681 tgtaagctgc atcttgttta tcaaagacat ctgtagatgg catgctgact acgcggattt
     4741 tttcgccttg actagccaat tctttagcag ctgagacagc aagattaacc tctgaacctg
     4801 tcgcaatcaa gatggtatca aagtcggctg cattttcata tacaacataa gcacctttag
     4861 caaccttgtc gaagtctgtt ccatcttcaa cagtcaagtt ttgacgtgtc aagacaaggg
     4921 cagttggtgt tttctcactt gtcactgcaa ggtaccaagc tgcttgcgtt tcacgcgcat
     4981 ctgctggacg gaaaacattt agatttggca tagcacgaag acctgctaaa tgctcaactg
     5041 gttcgtgagt cggaccatct tccccaactg cgattgaatc atgggtaaag acataagtca
     5101 caggaagtcc ttgtaaggct gacaagcgga cagctgcctt cacatagtca gagaagacga
     5161 agaaagttcc accgtataca cgaagtccac catgaagggc catcccgttc aagattgttc
     5221 ccattgcaaa ttcacgaaca ccaaactgaa tgttacgatt caagcgattg gtatcgtctt
     5281 gaagtccatc cgtcttgata taagtcatgt ttgagtgagc aaggtcagct gatccaccta
     5341 ggaaggttgg taatttagct gccacaacat tcaaggcatc ttgacttgaa ttacgagttg
     5401 cttgagaaaa accattttct aaagctggga agtctgctgg agtcacttcg actggatcac
     5461 gtccgtcgat gatggcttct acttctgcag ccagttctgg atgagcttct ttataatctg
     5521 caactaattt agtccaagct tgataagctg atgcgccacg gtctgcaaca tgttctttga
     5581 aatcagcata tacttgttct ggaatttcaa atggttcgta gtcccaaccg agggcttgac
     5641 gagttgatgc agtttcatct gctccaagag gggcgccgtg tacagcatta gttccttgtt
     5701 tgtttggaga accgtatcca ataaccgtct tcacttcaat caaagatggc ttgcctgaag
     5761 cttttgctgt ttcgatagca gcatggatgg cttccaagtc tgttccattt tcaaccaagg
     5821 cagtatgcca accgtaggca ttgtaacggt cacgaacact ttctgtaaag gaatcctttg
     5881 tctcaccatc caagttgata tcatttgaat cataaagaac aaccaactta tcaagttttt
     5941 gcaaacctgc gtatgaagct gcctcgcttg agacaccttc catcaagtct ccgtctccac
     6001 agataacgta agtatagtgg tcaaagatat tgtagccttc acggttatat ttggctgcca
     6061 agaaacgttc tgcttgggca aaaccagtag cagttgaaat cccttgccct agaggacctg
     6121 tcgtagcatc aatccctgcc gtatgaccaa attctgggtg acctggtgtt tttgaacccc
     6181 attgacggaa actcttaatc tcatccatgc tgacatcttc aaaaccagaa aggtgaagaa
     6241 gagcataaag gagcattgaa ccatgacctg ctgaaagaat aaagcggtcg cggttaatcc
     6301 agtttggttg agctggattg atatgaagtt gttttgtaaa gaggctgtaa gccatcggag
     6361 ccgctcccat aaccacacct ggatgacctg agttggcttt attaatggcg tcaataccta
     6421 gaaaacgaat tgcattaaca gatagatttg acatagaatt tcctttctat tgaggtgatt
     6481 attgaatcac acattctatt ttactattat atgaaaatta tccgtatcat gcaacatacg
     6541 gataacctcc aaagaatatt tttatattat agcaaagctt taaattgaat gttagagtct
     6601 tgttcaaaac aatcatcaaa accacgtgga tgatggtatt ctactaagtg ttgatcttga
     6661 ggataagtgt acttaccgcc aacttcccag ataaatggat ggaaatcgta ttgcaagcga
     6721 tcttttcgca ttttccaaag ttctagaatc tcattagtag aagccatgaa gttagaccag
     6781 atatcatagt gaactgggat aatgactttg gtacgcagat tttctgccat acgaagaagg
     6841 tcgatagatg tcattttgtc ttggatacct accggatttt caccatagtt attcaaagca
     6901 acatcaattt taaagtcttt accatgtttt gcaaaatagt ttgagaagtg agaatctgca
     6961 ccatgataga tggttccacc tggtgtttca aagatatagt taacagcctt ttgagccatt
     7021 tcttcatctg taacagccaa gccagcaagt tcaccgcctg tctcatcagc accgttcact
     7081 gggagagtta ccaagcaagt acggtcaaat gattctactg catgaatctt catatctttt
     7141 aattcgatag tgtcacctgg tttaacaacg atgatacgtt cttttggaac accccatcct
     7201 tcccagattc gtccacagtg gtaaggaccg ataaacttaa catgctctaa cttaggattg
     7261 ttgagaattg ctgcagctgt gtatgggtcg atatgatcac tgtggaagtg tgaaactaag
     7321 taatagtcta gttcgttgat agcaaatgga tcgataacca ttggctgaac acgcaagttt
     7381 ggttgcaact tacgaacacc tgccatattt gccatttggt gcccacgaac catatctttc
     7441 acttttttgg ttgattttcc acggtttgac caaaggtcca tgacaacgtt agcaccagct
     7501 ggtgtcttaa tccaagtacc acagttgcct agccaccaca tggcaaagtt gccttcaggt
     7561 acgacttctt cttcgatttc ttcgttcaac catgttcccc actctgggaa agtggctaaa
     7621 atccatgact ctcttgtaat ttctttgacg tttggcatat gttgcctcct ttggatataa
     7681 ttgttatctt tgagattagt ataccaccct tcaaaacact aaaaaagacc aagaaaaaca
     7741 caggtttgtg ttcatcattg gactgtcctt caaatatctt ccaaaaaagc ttgaactact
     7801 atttcttgat ttataagtgt ttgaacctct tcttggaact tactagccaa cttgctgtct
     7861 acaatataag acgaaataag actagaaaga ttttcactga aacttttgct cttattacga
     7921 aatatattgt gtttaagata gtctagcatt ttcaaaatat cttctgcttc aaggatagga
     7981 ttaaccctta aaatcggaaa tctgctatcc aaatcatcat tagtagtaat cactacatca
     8041 acttgtgcaa tatcttccac actcttaaat tgttctgttg taaatacagt gtcaatttgc
     8101 tcatttggaa aataaagttt gcattgtttc agcaaaagtc tcgaaaccgc aacaccttca
     8161 tcacaaacga gataaacttt tttcatattt ttttgagacg atggtgtata ctttaaaaat
     8221 cctccaatat gaatcgtcaa ataggcaata tcatcgtctg ttagccgaat aaaccatgct
     8281 ccttctaaaa tttccgcaga ttttctagtg actaaaaata attctccata cttggatcga
     8341 atttgttttg ttagaggatt tttagaaaaa ataccgtaag tctttctaaa taacaaggct
     8401 ttacagtgga tcatcaaatt tcgtaacaaa tcatccttgt tctcaatctc cattcggatt
     8461 tgtgattcaa aataccagat aaattcttct aaagcaagtt ttaattgccg aaaatcatca
     8521 ctttctgcat gaatatccaa atctttacga taggagagga ggagaacagc tacaagagaa
     8581 acttcaagtc ctgacaaaga aatttcaaac ttttgaaaca accgttctcc taatttctta
     8641 gacacctgat actctattct ttttcttatc aaagaaaact ctttctctat atcctgatgt
     8701 ctttcttgat actgttcaac attatgacag cttaacagca aataaggtag aacctgcaac
     8761 ataaaagtta tttcatgatg atttattttc ttccctaaat cttgttcaac taaaggaacc
     8821 tgttccttaa aaaattggtt catttcaaca gaaagcaaac actcatcatc taacctctct
     8881 ttcatcttat cttctaaaat agatacaaaa gtggcatttt cttccataaa aatatgatat
     8941 agaagcgatt gaagatactg aattttatta agagggtggg catgaaggtg gtatccctgt
     9001 gacttgctca cttgcaaggt cacctgatat tgttccaaag ttagttgata acgaatgcta
     9061 ttcaaatcat tgagaacagt attcctagat acctctgtta actctatcaa tttttcaatc
     9121 gtaatacgtt ctttagaaat acctatccat agtaacatta tcatcatacg ttcatgcgca
     9181 ctcatgatat aatcgtacga atctacttcc gataatagtt tacaacaagc atctctctgc
     9241 tcttccgtta agtgaatacc aattcgtgga atactaatga tgtgaagcgc ctcgtcaacc
     9301 agagcagcat tgattttgtc aatgtgataa taaattttcc ttcttgactc tttcaaatct
     9361 ttcgaaatcg ccataatcgt tttggacgtt tcttgatcca tcaaatattg aagcaaatca
     9421 caacttgcct tatccagtac catattaaaa aatcccccaa atctattgat atcacagcaa
     9481 ttctttttat tttaccatat atatatcaag cgctatttct aaaaaatctt tcaaaattac
     9541 ttcaactcca actttactct caataaaaat caaatgtaaa aagaggagct aaatttatct
     9601 ttttcttctc cttcatcgtt cttacttttg accataataa gcatttggtc catgtttacg
     9661 ttggtagtgt ttttctagta tgtactgggg agcaggtcca actcttggat tgatttgttc
     9721 tgtaaagcga ttcatctttg atacttcctc tagtacgaca gagtgataaa cagcattctc
     9781 tggatttttg ccccaggtga atggaccgtg attgcgtaca acaattcctg gtacttcaac
     9841 cgggttaagt ccgcgatgtt caaactcttc tacgataacc aggccagtat ctttttcata
     9901 ggccacttct acttcgtcct tggtcaaact acgggcgcaa gggattgaac cgtagaaata
     9961 atctgcatgg gttgttccgt agaaaggaat atcacgacct gcctgagccc aaccaacagc
    10021 ttctgtcgaa tgggtgtgaa ccacactacc aatttctgac caagtcttat ataattgcac
    10081 atgagttggg aggtcggaag atggtcttaa atccccttct aggatcttac catctagatc
    10141 agtcactacc atgttttcag gtgtcaattc gtcataatcc acgcctgatg gtttgataac
    10201 aatgacaccg agttcgcgat tgacttcaga tacattcccc caggtaaatt tgacaagtcc
    10261 atgttttggc aatgattgat tggcatcaca gactcgttta cgcatagcat tgattacttg
    10321 attcatctta catcaaacct gctttcttaa tgagtggata gagaaaagct tgcgcctctt
    10381 gaatggctgc gcgtgtttct tctactgttt cacaattttc agaccacatt tcgattagga
    10441 aaggtccatt ataattggtt tcctttaaaa tatcgaaagc ttcttcccat ttgacacaac
    10501 cttgcccgaa aggtacatct cggaactggc cctttgaact ttctgtcact gcataagtat
    10561 ccttgagatg gagagctgcg atggcatgat gaccaagata aaactcacta tagatatcat
    10621 tatgccatgc agacacatta ccaatatctg gatatacaaa gaggaaggga gagtcaatct
    10681 ctttttctat agccaaatat ttttcgatgc tactgatgaa aggatcatcc ataatttcaa
    10741 tagcaagtac cacctgagct tcttcagccc agtcacaggc ttttctcaaa tttttgataa
    10801 aacgttggcg tgtctggggt gacttttcct catagtaaac atcgtaacca gctaattgaa
    10861 tcgtacgaac tcccaagtct tgagctaatt cgatacattt tttcatgagt tctagagatt
    10921 tttcctctag aactggatct tttgatccca atgggtagcg acgatggcct gaaaaacaga
    10981 tagaaggaat acgaacacca gtttcataga tttctttgac aacttccaag cgttcttcct
    11041 tactccagtc aagtcttgct aaacgctcgt cacgttcgtc aatagacatc tcgacaaaat
    11101 caaagcctaa ctccttggca aaatttaaac gttctagcca agtaaagtgt gttggggttg
    11161 ccttttcata aattccaatt ggacgtacca tgatttaccc ccaaattcgt ttgatttcat
    11221 ccttgaaggc acgcgctgct cctgctggat ccgcagcctc tgtaattcca cgacctgcga
    11281 taaaggtaaa gacatcaaca ccttcaaaga gtttgagagt atctacatct agaccacctg
    11341 ttacagatac acggaagccc atgtcaatga gttttttaac cttattaagg tctttttcac
    11401 cccaagtttc accagcaaga agagcatcac gagattggtg ataaatagct tgtgagatac
    11461 ctgcatctag ccaaagctga gcttgttcaa aagtccaatc gccataaagc tcgatctgga
    11521 tttcgcctcg ttcgcctcgt tcagtcttga tagcctttag agctgcttcc atagtaggga
    11581 tggttgcaca acagatacaa gtcatccagt ctgctccacg aaccgcatta tttttagcaa
    11641 ctgttccacc agcatcagca cattttgtgt ctgccacaat aatcttatct gggaaaaggc
    11701 tacgcaagac ttcagccagt tcacttccaa cttgaagcaa gcaaacagtt ccagcttcga
    11761 taatatctac ttcctgacca acagaaacag ctgctttaat cgctccttgc aagtctgaat
    11821 ggtctaatgc aacttgtaaa ttaggtattc tttttgtcat ttctttattc ctctttctaa
    11881 ctttccaaat ccaatccttc gagataaggg ctatccttag attcttcaat catagccaag
    11941 acatcttctt tagtctggca agcctgtaaa cgtgcaatag aatcttctaa ttcaaacagg
    12001 gcaataattt gtggaatggc tacacttgtg tgaatttttg aacttgttgc tgctagtgcc
    12061 aacaaaacag atacctcttt cccatctgaa aatacaacag gattttgtaa ggtaatcaat
    12121 gaaaaggcat cactttgcac accagcttca ggtctagcgt ggggcatagc catacctggc
    12181 atcaagatat agtaaggccc atactcttca gtcgattcaa tgatagcatc gtaatactct
    12241 ggcaaaattg ccccactttc aatcaaggga tctactgcta ccttgactgc ttctttccaa
    12301 tcgttagcct ctaaacctag tcggatcgag tcgttgtcaa ttaaagcttg ttttaaattc
    12361 atatctgcct cctttattta aagagggaga aggacagaaa cgataactct cagtttctgt
    12421 ccagccccct ccaacctttt actgtagtgc ttgactgagt ttttcggtga tttctttatc
    12481 atccatcaag ttatcaagcc caattaactt cccattagtt cgcccttcca attcttgaat
    12541 caaatgaaga gaagcgatta cgatgtcata tcctactgct aaacctttag cttcaccgac
    12601 actgcatgaa ttgactgtaa aatctgtttg attaagctta cggagagcat tttcaacctt
    12661 catcttgata accattgatg aacccattcc atttccgcac gctgctaata ctttaaccat
    12721 tttatttctc cttttctaga tactaagctt cttcttgaac ttcaccgttg taatatttct
    12781 ctttatcttt tgctttggca aattgaagtt gaggaataac aagcaagaag agacacacaa
    12841 gtacataacc aacaatacca aggtatttga agatatatcc aaatccaagc catgggaatt
    12901 caaagtcgat atttccatgg tagccaccat aagatgccaa atcgagaagg gccacacaaa
    12961 gagctcctag agcaacttga aggacacctg atataaagga aaggataaca gccgctttcc
    13021 atccgccgcg tttatcagcg tagaccgcaa tggctgcatt gtcaaagaac actggtacaa
    13081 atcctgtaat aataagaatc ggatttttaa agacgatgag caaaacaatt gtaatcaatt
    13141 gaccaatcaa accaaagata aatcctgaca ggacagcatt tggagaacca aatccataag
    13201 aagctgcaac gtcaaccgct gggaatgaac ctggcaacaa tttgtttgaa ataccttgga
    13261 aggcgtttgt caactcagat acgaacattc ggacaccttg catcaaaacg aacaagtaaa
    13321 ctgagaaggt aaaggctgtt tggataatgt acataaagaa atcttgttta gcaggattga
    13381 atagagttcc tgaagtgatg acttctttat tagacataat gtctggaccc aagattaaaa
    13441 gaatggctcc gaagaatacg agcatcaagg tagcagatgc aacaactgta tcgtggaaga
    13501 ttgagaggaa cttaggtaat ttaagattgt ctaaactttc ttatttctta ccaaagcgtc
    13561 ctgctacttt atctacaaac cagattgcaa attgctgttg gtgaccaatc gcaaatccgc
    13621 caccaccagt caagcgttga gttgcctcaa cagtcatatt tgaactaact gcccagtaaa
    13681 gtccacagat gataccaatc gctgctgtac cgtaagcatt gcgcaattgt ggtactaaga
    13741 atagaaccat aagagatact gttgcagctt gttgtaccat gatgtgacca gtaataaaga
    13801 gggttcttac cttcgtaatc tttcgaagag ctacgagcaa gatatttatt ccaaaaccaa
    13861 tcaatagagc tgtagttgca gttccaacaa aatctggaaa ctctgctgca attttgttgt
    13921 ttgctgcagc aagtccaaag taagggtcga taaccgctgc accaatttgg aatttgtagt
    13981 taagagctgc taagattgga cgaaaggttg taaccaaacc accagcaccc acgttaagca
    14041 acatataccc tactgttgct ttaacaaacc ctgaaaaaac gtcatgggca ggttttttca
    14101 aaagtgcata tcctatcaac accaataaac ctacgaaaaa tgcgggattc tgcaaaatat
    14161 tgctagaaaa ccaatttaga acacttgaaa cgacttccat aattgttctc cttttgaatt
    14221 gtttttgtaa gtttattata taatgcgaaa gcgcaaacaa aaagaccaag aattacacag
    14281 cggactgttc actcttggac tgtatgattt atgatgtttt acaaattatc ttattttctc
    14341 gtagctagat aatagggaag aattttagaa taagacttca ataagccttc tacgatttct
    14401 tcttcagacg aattttctgt cataggaaca tctaccttca ctaaaacttt tcgaacttct
    14461 tgacttctca ccttctcgcg taaagtacga cgcttttctt cattcgcctc ccaccgttga
    14521 ctttgaccat tagagtaggt tagataataa atccctttaa cggttggaat gtctaaaact
    14581 ttggtctgct tgcccagtgt ttgctcatcc ttcttacgtt cgatgaaact gacttccaaa
    14641 gaaattccaa agtcagtaga tgtcccatac aaacgtaagg ccatcatagg ttctgtcact
    14701 tgtccgtctc tctgtagata aacccaaaaa tgtggtctca aacgctgggc ctgattcatc
    14761 cactgactag tctgttggag ttgccattct ggatggcttg cttgaaaggc tttggccagt
    14821 tctgtaaaag cctttcgggc ctcttgtcct ttgtggcgga acgccagcat cttctctcgc
    14881 tctgctcccg ctttatcagg actacggtac tgcaaaccag aaaagtctag atagtctctt
    14941 atcttattca acatcagttt aacctcctct agctagcaaa aaatcaggtc aaccctgatt
    15001 ttacttattc tgtatctaca acgacatagc gatttggctc atcaccttca gagtaactgg
    15061 tcacgccatc catacgtgaa ataatacggt ggataatctt gcgttcacta ttcgacattg
    15121 gatctgtttg atgactgcgc ccttcttcta aaacacgaat cgccaatttt tgcgcatagg
    15181 tctgcaagac ttctgcacgg tgttcaacat aatcattgac attaatagtg atatagaagg
    15241 ttcttgaata gcagttgtaa agataatttt gagccaacag ttgcaaggcc ttcaagactt
    15301 taccatggta gccgataata cgacctggtt cgttagtatc aatttgcaaa ttgatgctac
    15361 gacggttata atcatttgaa agtgtagcct caacatccat gtcatcaata atcgtttgaa
    15421 cataagcagt cacatccgta gccacctggg caatatcata actttgctcg accttcaagc
    15481 ccatctcttt caagtcttga ttttcagttt gatcttgctc agtttcaagg tcatcagcgc
    15541 ctgcttcttc cctcatcgct tcctcgattt gaagttcatt taaaatctca atgtgaccag
    15601 tttcttctaa gatagtgctg gcatgtcttt catgttttaa gatttcagcc ttgacttcat
    15661 cagaaatacc ttgaccttct tcctctattt ttttaatagc atcaaccaca tgaccaaggt
    15721 caacggtttc ttcactaacc gtcttcacag gctcgttcaa atcattgatt tttttcggaa
    15781 cgccttttac tacctgttga tttgctttga caacagtcgt ttcactaatc gcttcaatat
    15841 ccacttgggc tggtttttta ccaaatagac caagaaagcc ttttttctcc ctagaaatga
    15901 ctttgatatg agccttcatt cttggaatat ctaattcttt caatcctttc tggattgctt
    15961 cttcaacagt tgaacctgta aatactacca ttaccagatt cctccttatt tatttcgttt
    16021 tctgagcctt tttcttggct tttctttttc tattttccaa atctttttgt gcctgtacta
    16081 cggcctcgcg ctctgcgata atcttgaatg gattattcaa gaaataggtt tgcaagactt
    16141 gataagcatt agacactgtc cagtataggg cgactccacc tggcgcataa actgcaaaga
    16201 taaaaatcaa gactggaatc ccatacatca tcgcagtcgt agcgccattt cgctcagaca
    16261 aagctttgtt ggacaaccaa gtacttaaaa aggtgaatac tgctgctaaa atcggaagaa
    16321 caagggttgt atccacacta ccaaggttaa tccataagaa atgacctgtc tttaaaaagt
    16381 caactcttga tagggcttgg aacagggcca aaataaccgg catctgaatc aaaatcggcc
    16441 aaagagagtc tgactgtctg acacccattt ctttaaatac tttacgcatt tcctgctcta
    16501 gtttggttct gctttccata tctcgacctg gatattgttc tcgaagcgcc ttaatgcgtg
    16561 gctgagcttc ctgcattttc ctagaagcca ccatttgcac ctgaaagact ggcaagagga
    16621 ctgtacgaat caagaccgta aagagaataa tccccactcc gatactaata tcaaacgata
    16681 aaaagcgaat aatttccgca aagaagtaaa ccaatttact ccaaaaatca gccgattcgg
    16741 ctgtaatatc gctagttacc ccattagtcg cacaggctgt catgattaac agagacagtc
    16801 ctagcaaact agtcaacttt agtttctttt tcactcccat ttccttcccg gtaaatcttt
    16861 gataatttta atacatggag tagatttttc tccatctctg cgtatcccaa ggtttcgact
    16921 ccttttcgag caatgacaac aaagtcgaca tcttctacca gactcccttt tgcattctgg
    16981 ataatatgcc gaatccgtcg cttaatttga tttctagtga cggcattccc cagttttttg
    17041 ctaactgata gacctactcg aaaatggttt ttctggtttt ctaattggta gaccacaaat
    17101 ttgcgattag caaaacttgt cccctccttg aaaatcgcct taaaatcttt ctctcttttt
    17161 acacgaaagt ttttcttcaa aactcaactc catctattaa attactacta ttataccata
    17221 tttttcaaaa aagccaatca tagcaaggtt ttggacaatt tcatcagaaa aagaagctgg
    17281 aaaaataact ttcccaactc cttgtattga atattttttt agtttcactt attttttcaa
    17341 gcgttcaacg tcacgggcaa tgactaattc ttcatctgtt ggaataacca agacacggat
    17401 tttagctgcc tctgttgaga tgtctcctgt aacgccaaag acattctttt catcatcaac
    17461 atcacaacca aaccacgaaa tccctgagat tacatcacga cggaaactct ctgcattttc
    17521 accgacacct gctgtgaaaa caatggcatc tgctccattt agcactgcaa ggtactgacc
    17581 gatatgtttt tggatacggt caacatacat ttcataagcc aagctagcct cgtgattccc
    17641 ttctgctaca gctgcttcta tatcgcgcat atcgctagaa ttagcagaaa ctcccaaaag
    17701 acctgattca cggttaagaa cacgactgat atcttctggt gtgttaaaat cctctgtata
    17761 ttgcattaaa taaggaatga tagctggatc aatatcccct gtacgcgttc ccatcataat
    17821 accaccaaga ggagtgaacc ccatagaagt gtctacagat ttgccggctt tcacagctgt
    17881 aattgagcct ccgttaccaa tatgacaggt aattaacttc aagtcttcta atggacgtcc
    17941 caagagtttt gcagcttctc ctgctacaaa ctggtgactt gtaccatgag caccgtattt
    18001 acgaaccttg ttttctgtgt aatattttgt tggtagaggg tagcgataag ctttctctgg
    18061 catacttgtg tggaaggaag tatcaaaaac aactacactg gtaatgtctg gcaacaattc
    18121 cttgaaggca cgaacacctg ctgcatttgc cgggttgtgt agaggagcca acaaactcaa
    18181 ctcttcaact ttttctaaaa catctccctc aacaactgtt gattctttga aatattctcc
    18241 accagcaaca acacgatgtc caacacctgt aatctcgtca taagccttga taatatcgaa
    18301 acgaatcaag tcatccaata aaattttaac agcttgtgta tgattttcaa tatccaaaat
    18361 ttgttgttca gaacggccgt caaattttac agttgaaatt gaatctttca aaccgatacg
    18421 ttcaatcaaa cctttcgcca atactttttc ttctggcatt aagtataatt gccatttcaa
    18481 acttgaactt cctgcattga ttgcaattgt ttttgtcata acatgatacc cctttttaag
    18541 cgttttcaac tattataaca aaatctattt tatatttcag taccttgagt ccatttttga
    18601 aaattttctt taaatttcat taaaacactt gcatcttgca agctagcaag tggataaaca
    18661 aaaggctcta ctgctatttc acttttcttc tgtaggataa aaatagtctt agattgttta
    18721 gcattagcaa agagattttc aggtaaacta atcatagcaa ccagacttgc ctcctctttc
    18781 aaccagactt tcaacaaatt actttgagga ctggtcaaca aatcactcgg agctagaaaa
    18841 atagcgtatc cgtctgactt gaggtactta agtccttgtt ccatgagcaa gtgatgggtg
    18901 taagtatgtt cttgactaga agcaacttga tggcgcgacg caacggcatc atcaggataa
    18961 tagccaacag gcaagtcgct gatgaccaca tcactttctt tgagcatttg tggacgaact
    19021 gcatctcctt ggacaaagcc agcctgcaaa ccaattacat ctgccatgct agctgccaaa
    19081 tcaatcagca aatcatccac ttccattccc aaataatcca cctttttagt aagcgaggtc
    19141 aagaaagtag cgcccaaaat tcccatccca gaacccattt cgaggatagt aatttcctcc
    19201 tctttaaaca gctcttccac aataaacacc aaaagtaaag caatagcatc cggtgtaaac
    19261 tggtgattgg cctgcaaggg ttctgtttgc ccagccttca tcaagagaaa ctggtaggtc
    19321 ttgagccatt cttctttgcg tagtgctaaa cgcttaaggg tctgattgtt gtctttgacc
    19381 tgttctagct cagtctcacc atccagatag atgctgtttt gctccaccaa ggcgtcataa
    19441 aagttggtcg ccaaatcact ttggatgact tggacattct ctagtaaata ggtataagct
    19501 tgttcaattt tttcaaaatc catattccta tcttatcaaa tttcccttct tttttccatt
    19561 cttatagaaa aatcactccc tgactaggcg agtgattttt gggctactat taaaaagaat
    19621 tctgagtgat ttccttgaaa caggtcttca gcgctataga gaatctgact atgcacagat
    19681 gaaaaaccat gctcaattag cttgttttcc agttcagcta aatcaaatcc atgatgatta
    19741 gcttctgtct tggtaaaatc agcaatgatg agtttcccat cttccttcaa atgttgatga
    19801 aacagtgaga gagccgcatc caaatcaggc atatgatgaa gaacccgact aacagcaagg
    19861 caatcaaact ctttctccaa gggatttttc ggtaaatctt gctccaaaaa ctggatattc
    19921 ttgattgctt gctgctccac tttcaaacga gcttgctcca acattttctc agaaatgtct
    19981 acaagagtga ctgacttagc ctgcttggct aggggttagg ggcaaggcta atagacccgt
    20041 gccaccaccg aaatctaaaa tttctttgta tgatagaaga tcaatctgtt tctcggctgc
    20101 ttgacatacc aagtttgcga ggaagatatt tttagggaaa tcgaaagttt ctgctttgtg
    20161 gttaaaatca tgtttcatat ctttaattta gcacaaagta tagtaaactg aaataagata
    20221 taaacaaatg aattggagct taacatccat ttccagcaat tttctagaaa ctacagtgga
    20281 ctattctgga ttcaacgcat tatagttgaa ttgactagga attctctttc ttttcaggct
    20341 tctcttctga ttttttcttc tccacttttt cgcttgaatc ggtcgctacc tcttcctttt
    20401 tatctctttt ctcttctttg attttgactg aaggaaacag aaactcatat tggctcttat
    20461 ccgtacgaac cctcgtcact aagccagttt tcttgttttg atagcttacc tgacctagat
    20521 taaaaacctg ttccccactt tcttgctcaa ccttatcttt ggttcgttta gccatagcaa
    20581 aagcaaccaa tttttcttta ttcaaagcat agtcttgata gtgggcgact tgtcggttca
    20641 aataaaattg caacaaaaga ctaaagatgg ctgctatggt gactgcgtag aggagaacac
    20701 ctgccttaac ttttttcttt ttccacacga tagatgaact ccctttctaa gcctttttga
    20761 aactggaaac gaaaatgaac cagttgattg tcctctgtaa tctgagctga tttgaggcca
    20821 taaaccatag gctgataacc tcgaccacga gcattcgttt tacgaaaatc gtctgacttt
    20881 gacttaccga tggcgatgtc cttgccatct tgcttcatgt ataggcgatt gccttctact
    20941 ttttcgaact gcgaacggtc taattctgcc tcaagttggt ccacaaacaa gagccactcc
    21001 ttttgctcgc tttgttgctg gtagcgaact tctgaaatga ggagctgact catagtttga
    21061 aaaaggagta atcccccact gatgacaatg agggcaagta gggattctaa caaggtaaaa
    21121 gccttgacct tatggctctt tgattgccaa caactgttct gaaccatggt agacctccaa
    21181 tcctttttca ctagaaaata cctgaatctc aactccgttg atgcttacct gattttgccc
    21241 cgtctgcagg gccatcttag ctaccctcaa gacttcttcc ttttgcaaga tttttgcttc
    21301 ctcttgccta tttttttgaa tttgtcccaa aaggagggtc gcaatgctgg caaagatagc
    21361 tagagcgact actgcttcca gtaaaatcac tgccctaatt ttttgtttcc ttaatgcgtt
    21421 taatttttcc atttcctaga tataattgat agcgaatcgc tcctttactg gtctgaaatt
    21481 caaccttagc cagggacgaa ttgcccccag cacggtcaaa tgtaatactt tggcctgatg
    21541 ggacctgaat tcctttaggg actggcaact tttgactgcc attgctaatc gtctgcccat
    21601 ctaagttcag actagtcttt tgctgactgg ctacactgcg tttttgggtt tcccgataga
    21661 gttcttcaaa ttccataaag aaaatctgtt cctctactgc cgcaaaagtg gactgaacag
    21721 agccggacaa gcccaaggca aggatactca caagacccaa aaccaagaga ctttccagca
    21781 tggtaaaggc cttaatcatt gactttacga tttgctcctc catttttatc attgtattct
    21841 ttataagctt taacctgttc ttccgtgatt cgcccatcgt cttttaactt gcttaggcta
    21901 gcatcttcat tcttttccaa gctataaagt tctgcctggc tttccaccac cttaacaaca
    21961 gctgcttttc ctttgtcatt gactgcttct ttttgcttgg tcagattagg tacaaagagc
    22021 aagaaaagca cgctgataat cagcaagacc accaacatct ccaccaatgt aaaagcttta
    22081 accttagctt ttttcaagaa tgtcatcatt tttttcattt taaaaattta cctccatatt
    22141 ttgatacatg ggcatgagca ttgccgcata aagtaaaacg ataatcagtg ccacaaagat
    22201 aaaaaccagt ggctgcacca aattcatggt gcggttgact cgggtaaaaa aggcttccca
    22261 agttttttca gcatagattt ccaactcact acccagcttg gacttaactt ccccatactc
    22321 tatgatgaga ctcaattcct tcctaaagaa aggataggtt cctatcgtct gagaaaattc
    22381 acggccattt ttcagggttt gagccagatc ttgaccgatt tctttaaaga gctgggaacc
    22441 ttgttcctgc atcatttgaa aaatctgcgt cagctccatt ccctgtgaaa tcatattccc
    22501 ccattcacgt gcataatagg ctgtcaagta ggtctgcaca aagattccaa taaagggaag
    22561 gcgtgctaag atagaaaaga cactcatctt agaacttctt ttataaaaag ttagtgctaa
    22621 aagggcaagc acggaaacaa gccctaccat gcctagaaaa atttgtggca gattaccgat
    22681 aattcgggtg gcaatattgc tactatccag ttgtgggagc aggtaattcc gtagccccag
    22741 cataattaag agaagaaaac ccagcaaaat caaaggatag gtcgctactt caattaactt
    22801 tttcttgacc ttggccagat tgtctagata ttcttctatc tttcccaaac tcaggtgaag
    22861 attgccatga acttcagcta gagataactg agtgacaatg gtacttgaac atcccaaact
    22921 ttccatcatt tctgagaatg atttcccctg agacaaacct gtacgcatct gggtcacaca
    22981 ctgcttgtcc aacaaggaac tcctatctaa aaaggagatg gtctccacca gatgaaaacc
    23041 gctagaaaag agattgttaa atagggtgat gatatttttt tgcttagctg tagctaattt
    23101 tttccgtctc agcctgaaga cttgtgatat gtccatcttt aagaagctgg tcaatttgct
    23161 cattccactt ggctgcttgg tgttcttgat aatctctgtt tgcaaagtca acgattcctc
    23221 ctcccccgat taatctctgg tagcagactc cttgcagaac aactgccaat tcttcttcac
    23281 tcacacccaa ctccagcaga cgctcataaa cacctcggat actcttggcg tgaatggttg
    23341 aaaagactgt cgcacctgtc aaactagctc tgaccactgc acgcgccgtc tcgctgtcac
    23401 gaatttctcc gataatcaag agatctggtc gatgacgcaa ggaaagtttg attagatttt
    23461 cataggttag gccgattgct tcgttcaact gcaactgaag catgtcgtcc tgcttgattt
    23521 cgacaggatc ttcgatggac ataacttgct gtcctttaaa gagtgacttg gacaattcat
    23581 gcatcaaggt cgtcttacca ctcccaaccg gaccagcaaa aagatagagt ccccgttgcc
    23641 tgtactgctt gcctaattct tcaatatcct gaaaccaaaa atgcaagtcc tgctcctcat
    23701 cgtgcaacaa acggataacc aaactctcat gcccccgata atcgcctaca gtagataaac
    23761 gtagagacgc tatcttctgg tcataggcat aatcacagga acccagttga ctacgtcttt
    23821 tttctcccac attcataccc gccacaaact taaagtgact gataacggct gcaaactttt
    23881 caaaatcata gctaccaatt ttacagcgct cgtctcctac cctcatatga agctcatagg
    23941 cgtctaactt ggggacaaaa taaatgtctt gcgccccttt tttccgagcc gagcgaatga
    24001 tttcttgtgc aatttcttga accatactta cctcctcacc tatactattc gcaaagcgtt
    24061 agaaaaataa aaaaagcaac tccaaaaaag ttacttttct ctattttaat ttcatacggc
    24121 aagaacgatt cctttcctga ctggtttgtt tttcatagcc tgagcgtagt ttttcgtctg
    24181 ggataacctg ctcatcctgc aaaagagcca aagaatggta ttgttgtaaa tactcatcac
    24241 attcatcaca ccagcgttgg tcttccgggt cccaaaaaat ggtcatcaag tcgcttctac
    24301 ttttataaag aggggattct tgttccaatc taaaccagca agttttgtag tatttgagag
    24361 catcataata ctggtcaaat tttctacttg ctacaatatc ttcttcccaa ccttctaaga
    24421 accaccacgg ttcaaaatct ccgtacattt ctataacacg atacatattc attcattcct
    24481 ttgtaccgta tattataacc aattccgcca gacaaggaaa gaaatatgct catttcttaa
    24541 ttttttgata aaaaatccag ccatctgatg gatgactgaa tttctattta cttatgtaca
    24601 aaaatatttt tactacttag gcttctgaga tatcgttttc gataatgacc ttaatggcat
    24661 ggtggtctgc tgccttactg aagacttcgt aggctttttc aatttcactg agtttgaaat
    24721 agtgagttac caatttttct ggttcaatct tatgactttc aagcgctttc aacaattgtg
    24781 gagtcgtatt tgtagatacc aaaccagttg ttacattgat gttgcgaatc caaagtttat
    24841 ctaaatcgaa ttcaactggt ttaccatgca caccacagtt ggcaaccgtt ccgtctacac
    24901 cgataatctt ttgacagaaa tcaaatgttg caggaatacc aacagcttcg atagcgacat
    24961 ccacaccacg accatctgtc aaatcataaa tttctttaat ggctttttca gggtctgaag
    25021 aattaacctt atgagtcgca ccgaatgata gggcagtttc caagcggtta tcgtctaggt
    25081 ctaccataat caatttagct ggtgaataga attgggctgt taaaagagca gccaatccaa
    25141 ctggacctga accaataatg gctacgctgc aaccaggttc tactttccct tttaagacac
    25201 caatttcata tccagtaggc agaatgtctg acagcataac caaagcttca tctgacaagt
    25261 cttctggagt atggtaaaga gtattatctg catgagggac acgtagatat tcagcctgca
    25321 taccatcaat caagtgaccg aaaatccagc ccccttcgtc ttcacagtga gcataaattc
    25381 cttttttaca gtagtagcat ttaccacagg cacagacgca agaaatcaag accttgtcac
    25441 cttttttgaa gttggaaact ccttccccaa cttcttcaac aatcccaatc ccttcgtggc
    25501 caagaatggt accactttgg caagtaggaa catccccttt gataatatgg aggtctgttc
    25561 cacaaatagt ggtttttaca atacgcacaa tagcgtctgt tggcttgcga ataactggtt
    25621 tgtctacatc aacaaaagaa gcaagtcctg gtttaacata agtataggct ttcataaagc
    25681 actcctccgt ttttttattt gtaatattta tagttcaatt gtaagccttt ttctttgttt
    25741 cttcaagctt tttttgtgat ttttttaact ttttatttac cagtaaagta ccctgcataa
    25801 aaaagcagaa gttagtctct aacttctgct ttctctctta tgcttgataa cgttttacgc
    25861 catctaggta ggttgctacc aattccaaat ctttatctaa tacgatgaag tcagcgtcgt
    25921 agccttcacg gatttggcca cagacgtcat cgatgtgaac ggatttagct gggttgaagc
    25981 tggccatcat gactgcttca tgcggattcg caattcccca ttcgaccaca ttcttcaaac
    26041 catctttgag tttgaggata gaacctgcca agttacctgt cgatttgagg cgtgcagttc
    26101 catttgcaac gacaactggg aattctccca acatataatc tccgtcttcc aatcccccag
    26161 ctgtcataca gtctgtgata agagcgatgt tttctgttcc tttttgtttg ataagaattt
    26221 cgcaagcctt tggatctacg tggtgaccat cacagatcaa ctctgcatag gtatgtggca
    26281 attggtacat ggctccaacc atacccaatt cacggtgagt caacccacgc attccattgt
    26341 aggcatgcac ccaaacactc gctccagcat cgactgcttt tttggcttca tcaaaagtcg
    26401 cgtttgaatg tccaagagca accgtcacac cttcgcccgt aactgtacga acaaagtctt
    26461 ccaccccatc acgttctggt gcaagggcaa ttttattaag caagccattt gccgcttttt
    26521 gccaagaatg aaactcctca acacccgggt ctctcatata agttggattt tgtgccccct
    26581 taaaagtttc tgtgaaatat ggaccttcat aataaatccc acgaatctta gcacctgttg
    26641 cttctttata atggtttcca agattttcag tgactgcaag caattgctca taagtggctg
    26701 ttaaagttgt gggtaagaaa ctggtaacac cggtactaag aagtccttca ctcatagtat
    26761 gcaatgtacc ttcaatgttg ttgtccatca catctacacc tgcatatcca tgaatatgag
    26821 tatccacaag acctggggca atgctataac ctgtatagtc aatcacctca gccccttcag
    26881 gaatctgctc tacatgtttc ccaaacttgc cgtccacaag ttccaagtaa ccacctcgac
    26941 gaactccgtg tgggtagaaa aactgatccg ctttaatata gttaggcata atgttaacct
    27001 ccttaaaaga ttgattctac aatttattat gtcaattaca ttataaacct ttctttttta
    27061 tttgtaaatg gtatagacct attttttgga gatattttaa aagagctgga tttctccaac
    27121 tcttctcttt tttaatacaa gttattttga tttaaccggc ttgtcttgag ctgtctgcaa
    27181 agctgtggca atcgtatctg catacaattt tgctcctgct tcgatagtgc tactctcact
    27241 cccgaaatga acctggtctg ttcctgccca aatttctgga tgctctttcg caacttgatt
    27301 ccaatctgct atcgtaatgt aaggtgtctt ctctgccaat tctctcatat aggcagcagc
    27361 cttctcaacg atggcatagg tctcttttgt cttatctccc tcataaggag tcaccaaaat
    27421 catatggtgt cccttaggaa gatttttcac gatactgtcc cagtcatcct tgtaattctc
    27481 aggattattt accccagtcg caatgaccac cgtcttaggt aaaaatttat tctggctatt
    27541 atttagcatg atttcatttg cggtcttggt tgttacgctg acctgcgcgt taatctgtgc
    27601 tccaggaaga gctgtctgta gtgctgtatt tgcccttaaa gccactgagt caccaattaa
    27661 catagtgcca tcagcaattc ccaaactgtt tgcatctgcc cgttctgcca tcaccttggt
    27721 ctggccaata tttgttgcag cttgcttcaa gccattgaca gtcaagtctg tctcaaacgc
    27781 tcccacttgt ggtgccaaca aggtcaccgt gcagacaatg atggtcaaga ttcctgtacc
    27841 tgctgcaaga attgcgtgaa tataaggcag gggacgaagg gtttggacaa taggtgtgtt
    27901 cttgcctgca atccaaggtt ccaatacata aaatgacaga ctggcaaagc cataagaaca
    27961 aatcagagtc agtaatacag caagaagatt tgatgtcaac tgtgagaaaa tgatatagaa
    28021 aggccaatgg aaaagataaa ccgcatagct agtatccgct aaaaagctga taatcttcgg
    28081 ctcctgtata tgatgtgtct tttcatgtaa gacacgcgcc gccagaatca tggcaagagc
    28141 tgcaagactg gcaagtaaga agccgataag ataggcaaaa agataagtga atttgacaaa
    28201 gaaagtcaaa agaactagga aaccaaagcc tcctccaaaa actaccaaag tctttcgtaa
    28261 atcccagatt ttatccaact gcttgacgag ggaagtcgtc tgacgaacgc ctacaatagt
    28321 tgctaacata cttcccaaaa agaatggata gacatgagtt aaactggaga aataaacaga
    28381 ggaataagag gtcactagaa aactaccaat aaacatggag aagaaactga tcaagaaggc
    28441 aacagcagat aagagaaaga ccatcccctt caactgacca tttgatttag cttgtttgga
    28501 taagaaccaa actgccaatc cccaaagaat atagtagtga acctcaactg ccaaactcca
    28561 attatgaaca aacaaatgag gaatgaactg agattcataa ctcccacctg ttaggagttc
    28621 atagaagttg gtcataaagc ctaagacgct cgcaatctgg ccaccaattc cagcaacata
    28681 gtcttggcga accaagaaag taaaaggcat ggtcaccaag accatcaaaa ccacaggtgg
    28741 cacaatccga taaaagcgtc ttctaaaaaa tcctatcaaa tcaatctcat ggtttttaga
    28801 aaattcttca atgagtagag ctgtaatcag gaaacctgaa aatgtgaaaa agacatctac
    28861 cccgaaaaat cctccaggaa agatcgtctg aaagaagtga tacaagagta ccaaaagtaa
    28921 acctgtaatc ctaaccaagg aaaaccattt aatgcgcata cgagtttatt cttcctttca
    28981 ttgtacactt tattctatca aaaaaagaag aaaaatccta agagaaaact taggattttt
    29041 agcttatatc aattccattt tagaaattac gtcctgactt attatagcca tatttttcca
    29101 caaaatactc acggaattcc aagagattgt catccatgat ggcttgtcgc acttgcttca
    29161 tcaggttaag caagaagtaa agattgtggt agctagtcaa gcggatccca aaggtttcat
    29221 cagccttgag caggtgacga aggtaagcgc gtgtatagtt attacatgtg tagcaatcac
    29281 actcaggatc cagtggcgta aagtcctcag caaactgggc atttttcaca accaaacgtc
    29341 cttgactggt catacaagtc ccgttacgag caattcgagt cggtaagaca cagtcaaaca
    29401 tatccacccc acgaatgacc ccatcgatca agctatctgg cgctcccaca cccatcagat
    29461 aacgaggttt attttcaggc agcagttgag ttgtaaagtc caagaccgca ttcatctctt
    29521 catgggtttc tcccactgcc aaaccaccga tagagtagcc tgagaaatcc atgctgacaa
    29581 gatcatgagc tgattggcgg cgaaggtctt caaatcctgc accttgcaca attccaaaca
    29641 aaccttggtc atgtggacga cggtgagcct tcaaaccacg ctcagcccaa cggctggtac
    29701 gctctatcga tttcttaacg tagtcataag gttgataaaa ctgaggacat tcatcaaagg
    29761 acatcatgat gtctgaaccc agattattct gaatagagat ggctttttct ggggatagga
    29821 acatcttaga accatttaga tgatttttaa aggttactcc ttcttctgtg atattacggc
    29881 tatctgctaa agaataaacc tgaaaaccac cactatctgt caagataggc tggtcccaat
    29941 tcatgaactt gtggagacca ccagcgcgtg caatgagttc atctccaggg cgaagccaga
    30001 gatgataagt gtttgatagg ataattcccg aacccatctc cttcaattct tcaggtgact
    30061 gagttttgac agtggcttgt gtcccaactg gcataaacat aggtgtcgga aaggtaccgt
    30121 ggggagtgat gatttctcct agacgagctc ctgtgtgttt ttctttctta atcaaacgat
    30181 atttgattgg tgaatctgac attttttacc tccgaagctg ggaaagacag tcccagttca
    30241 tacagtgtgc ccaaggacac actgtatgat tttatcaaaa aaagtaggaa ctgtcacgaa
    30301 ctatgtataa gaactatggt ataataagag aatgaactat ccaaaaattg atttaaaaac
    30361 aattcgtcag gagtcaaaac attttcaggc tgacaccccc cgtctctttc tcctctatat
    30421 ccttcccagt atgctggtca tcttatctag ttttcttaat cccttatctc ggatccacgg
    30481 gactgtttta gaacagccat ttttcagcat acttggccaa atacttcaag cctacctctt
    30541 tcctctacta gtctccttta tcgggactat tcttttgacc agttccgtct atgcaacact
    30601 gacactcatg aaagattcta aaacggagcc atctgtaaaa aacagcctag ctctctttga
    30661 tgaggagcgc ttttctcaaa cctttttgac cctacttctc aaacgtttct atctcttttt
    30721 atggagtatc cctaatttac ttgggattta tctcctcttt tatagtagct ttttagccaa
    30781 aaaattcgtc accctacatc ctgagtttcc aaatctagat ctctcatcag ttgaaaccga
    30841 gcgtttcctc atggtctttg gactctactt tcttgcaagt ctcatcttga tcattgtagg
    30901 aaatatcctc tatattccac agtattatgc ctattcacag gtggaatttc ttctctgtta
    30961 tagtctagac ctaggacagg tcccaccaag acgaatccta aaaactagcc gttcctttat
    31021 gaagggctac aagttccagc actttatcct agatttacag cttcttcctt ggtacttcct
    31081 caattggatt acctttggca ttgctagttt ttcactccta ccttatatcc aatgcactaa
    31141 aattatgttt taccgagcag tattggctcg aaaacgtcca aaagcttgaa ggtttttccc
    31201 ctcaagcttt tttctatcaa tgagtttctc cgcctaccaa cttgagttcc tgatccccat
    31261 gttctatcat agcgccgatt gctgcttcta tccctcgccg aatatccact aaactcatag
    31321 ttggagtagt cggtctgttc accacctgtt ccatcatata aggaatatgc ataaaacctg
    31381 ccttaacata tggaaatttc ttttctacca aatagagagc ctgatacatc aaatggctgc
    31441 agacaaaagt ccctgccgta ttggaaacag aggccggtaa gccctctttt tttatagctt
    31501 gaaccatcgc tttaatcggc aaactactaa agtaggccga agcaccatct gggcgaatgg
    31561 gacggtcaat cggttgatta tcttcgttat cagaaatgcg tgcatcgtct tgattaatgg
    31621 ccactcgttc aggtgtcaca ctagttcttc caccagcttg cccaatacaa aggacaaagt
    31681 caggttgata acgattcatc tcttcttcca atacttgagc agatttgtga aaaactgtcg
    31741 gcacctctag ccaacggacc tcagcaccat ggatttcagc tggtaaacct ttaatggcct
    31801 ccaaagttgg attgcccttt tcccctccaa agggctcaaa acctgtcact aatactttca
    31861 tttctaactc ctcaaaacca attcaatgag acttttttct taaaaacaag tataacatat
    31921 ttcccttatt ctggattaaa aaggattagc gagattagaa tcgaccttca agtgtatttt
    31981 aaagagtaaa atactaatca aggccaaaat agctgatcca ccttgcttca aaataatttt
    32041 tttatccgct gttaaagagc cgtaagtcgc agcaccaatc acaaataaga caaaaatagt
    32101 cacaatttct aaattctgtg agaaataaat gccataccag agaaagactc ctagcagagc
    32161 cttataaatc ccttgatttt tgaacaatga acttactgac ggatgagcca attcttcctt
    32221 ttccatatta aatacacgac tagtcgcatc tgatcgcgta gcaatacttt ccaaataaaa
    32281 aatgtaaaaa tgctccaaag caacgatcgt tgttaaaata attgtaataa ttgacatcta
    32341 tttctcctta aatttctata ttttcaatac ccaaaaccaa tttatttaat aaacggctga
    32401 gttctgttct ctcaaactct gttaagatac tttccatctc ttccttaacc ttgatatgtt
    32461 gcagaggggg attcaccact aactgctcct tggcatactt cgcagcctct accaacactt
    32521 cccgctgatt ttcaggatta cgatgacgct ccaccaaacc ttccgtttcc aaaatcttga
    32581 aatgccgtgt caaagcagcc tgatcaattt tcaaacgctc ctgaatcgcc atttggttac
    32641 aaggagaatg ctccagcaaa aacagtaaaa tctgataccg tgtcaaacta atcccaagcc
    32701 ttttttcaaa caattgcgta ctcgcttgct cagacaagcg gagttgatac agtaaatctt
    32761 gaatctctag catttcttcc cctctctttt tattgattta tcaatagttg actaattaat
    32821 tgtgatataa agtaaaatag attgcaagaa tgttgcttaa ctcattacaa gatgataact
    32881 ttccattttc cattcaaatt gatactcaat gaaaatcaaa aagcaaacta ggaagctagt
    32941 cgcaggttgc tcaaagcaca gctttgaggt ttcagataaa actgacgtgg tttgaagaga
    33001 ttttcgaaga gtatgacaaa gaaaaaacga acgagaatcg ctttccatca cgaaagctag
    33061 atctcattcg tcaaaatgat gttatcaagt cgggtttatc cattcattga aacgtgaacg
    33121 tgatcatagt gattttctgt cacactacca cggtctggca ttgggttcca agtgttagct
    33181 ggcccatatt tgctatcgaa tggagcatag aaacgttgtt tccagatgat gtaactaatg
    33241 ccacggctgg ccatattttg aatagcatat tccgcaatct tatcccctaa ttctgaacgt
    33301 tctggtacca taaagtcgat agccaaacct tttccgtgat ctccactgtc tcctggacga
    33361 taaccactaa aggatgtaat gccaaacaag ttagcaattt cttctttaaa ggcagctgtt
    33421 tgtggttgaa gacctgcatt ttcagatttt gctactgcaa gtccagcata atcgggcgca
    33481 gctggagcct cgtaagttgt tgaaattact ttcgtctctt ctggttgata agtagaaact
    33541 gctgctgtag ctccatttga tgatgctact tcttttgctt ctgaacttgt tgtagttact
    33601 tccactgctg atgcagcttg agggcttgct tgtgtttcct gcttctcagc tggagtcgtt
    33661 tcctgaggag ttgcttcttc aactgggcga gttgtttcgg tcgtttgctc ctctgggaca
    33721 gaagtgcccg tagatggtgc cacttcttca gaagcaatca ctgtctttgt aacttctgca
    33781 attggttgag aaaggtctgc aacctgaaca gtttgatcat caacggtcac ttgattagtg
    33841 gtcaaatctg ctgtcgcagt tgtcacttct tcactagagt ctgcttgagg tgtttggatt
    33901 tcaacttctg ttacttcttc tgcttcattg acagtcgttg tcaaaacagt ttctgggaaa
    33961 atcaagtcca tattagtgat tttgttcaga ttcgcaagca ctgtgacatc tacacccaag
    34021 gcttctgcaa tggtgctcaa agtatcacca tactgtacgg tataacttgt tttgttgtcc
    34081 gttttagtca aatcgttttg gatttgctca acactacgtg cagtccaaag aacttcttct
    34141 gcttgagttg ccaatactgg ggcaaatgac aaggctactg ttgacgctaa taacattctt
    34201 ttcttcattc tttcaaattc ctttcaaatg agtacctgtc tatcataaca caaaaaatgt
    34261 agaaaaaaag ccctctcggg cctatttaac agaactgtct attccttgta acaaactagg
    34321 ttacttgaaa tagtttgtta ggtctctgtc acaaaactga cacaatcttt ttatcactta
    34381 gtctcaaaaa tacgggaaat atctgctaac gcttgaatcc tgtgattccc ttcataagta
    34441 gactctaaaa agttgatgct ttgaatccca ctattctggg caaattccac atccagagtc
    34501 cgatccccta tataataagt attatcagaa ttcaactgat acttatctag cagataggta
    34561 gccgcttctg gacttggctt ccgcacaaag ccactctgac tggttaaaat ctctgtaaaa
    34621 taggattcca cccccaagtc cttgagaatg gtaaaagcgt tgttcccctt atgagtatat
    34681 ataaactgct gaattcctga ttcgtctgcc caagctagca cctcacgcgc acctggcatc
    34741 aaaactacct gagcattctt ctcagccaga ctctgggcac gcacctgatt tagcacctca
    34801 acatccagat ttctatcttc tgccacccgc acaagcaaat cttgcaccga atacttgaag
    34861 ataaactctc tcaccttctc cttatcataa ggaatagaaa actgagcaaa agtctcctca
    34921 atccctgata aaatcgcttc gtaagagtcc aataaagtcc cgtctaaatc ccaaataaaa
    34981 gctgtttttt gcatttccta tcctttcaag ctcatatagc gctggtaacg atagcgtaga
    35041 aataaccagc gaaaaccatt atccaagaga gaccctgccc aaataccagg caagccccaa
    35101 ccaagcacaa tccccatcag atatcctgtc ccaatgcgga tacaccacat tcctatactt
    35161 gtcgcataaa aagggaggcg tgcatttcct aatccctgcc agactgccgt atagatgact
    35221 gttcctgtcg tcataggggt cccaagtagt gaaaacagtg tcactagaac actagcctcc
    35281 accgctagag aatcagtcgt atagagatga gttaatggta cacccaagac atatatacta
    35341 aaggacaggg gcaacatgag gaacagagaa agccaaaagg tttgtttact caaactagca
    35401 actcttttcc aatcatcctc tccaactgct cgggccaaca gcatgaccgt tgccgtagcg
    35461 acgccaaagg caggcatata gttaaactgg gtcaagactt ctccgattgc attcccagca
    35521 actgcctccg tcccaaaaga aacgaccaag gcaatgatca ctacatctcc agccctcatc
    35581 ataagtcgct ctccagctgc tggtaaagcc aaggtcaaca gttccttatc taaaccaaaa
    35641 gttggcttcc cataaggcag ttttaattgt gaccacaaaa tcacaagacc aaccaaacga
    35701 gacacaattg tcccccaagc aacaccagct atccccatat ccagaacaaa aatagctaga
    35761 cttgaaaaaa gaatattcaa ggcattggat aaaaaactaa catagagagg cagacgtgga
    35821 ttatgcgttg cacgaatcaa ggctcctaga ctagtcatta aacctaagag aacaatcgat
    35881 ccgcctacca aagatagata cagtccacca ctctcagcta catccctctc cgtccccaaa
    35941 agtcctatca tctctttccc agcgaagatg gacaaaaatc ctaaaaggaa acttaatagt
    36001 aaggtaatct tcaacgcctc agtcacatga taggccaact tcgactggtc tttctgccct
    36061 atgctttttg aaataacact ggaaatagca gctcccagag cgatgaaaat cgcctgataa
    36121 atggtgataa tattaccagc tactgaaacc cctgaaatag ctatcaatcc taaatgagca
    36181 accaaataac tgtccaccat tcccattagc atctgcaaaa agttttcacc catagctggc
    36241 aatgcaatat taagaatgtc tttatttttc ttaaacaatc tctcctcctg atgaaaagaa
    36301 actcagttgg tttcccaacc gagtttgctc cctctgtctt aaagtcctaa ataagcctca
    36361 accgctgctt gcatgtcagc agctgccact gttgtcttgt gacgaattgg agctatttca
    36421 agcccatcaa ctgctggtgg cactgcaacg cctgagattt catgtaattg agccaaggct
    36481 tcaaagtctg ttaaacctgc ttttccagtt acagcttcta ctgcaactac tgggaacttg
    36541 tatggactag ctgttgaagc aatcactgtc ttagttacat ctccagtggc cgattggtat
    36601 tttttataaa ctgctgaagc aacagctgta tgagggtcct cgatataaga atctaactca
    36661 caaacacgct tgatctctgc tgccgtttct tcctcagtcg catattcagc tgcaaagagg
    36721 tccaaaatct ctgcatcaaa gtctgtcaac ttatattgtc cttgcgtgtt caaggcattc
    36781 ataagttcag ttgtcttttc agcattattt cccaaaagat ggaaaatcaa gcgctccaag
    36841 tttgaagata ccaagatatc catagatggg ctggttgtta ccttaaactc acgttttttg
    36901 tcatagacac gtgttttaaa gaagtctgtc aaaacattgt tgtcatttga agcacagatt
    36961 aatttaccaa ctggcaaacc aatttgtttg gcataaaagg cagccaagat atttccaaag
    37021 tttcctgttg gtactgtgaa gttaaccttt tcaccagcta caatttcacc agtcttaacc
    37081 aattgagcgt aagcataaac ataataaaca atttgtggca ccagacgacc aatgttcata
    37141 gagttagctg atgaaaattg caacttgttg gtagtcaatt tttcacgaag agccacgtcg
    37201 ttaaacatgt gcttcacatt tgtttgcgca tcgtcaaagt taccatcaat agcaataaca
    37261 tgagtattgt cgccagtttg agtggtcatt tgtaactctt gaatcttgct gacaccatcc
    37321 tttggataaa agacgataat ctcagtacca ggcacatccg caaaccccgc catagcagct
    37381 ttccccgtgt caccagatgt cgctgtcaag ataacaatct tgttctccaa accatgtttc
    37441 ttagcagcag tcgtcataaa gtatggcaaa atagacaagg ccatatcctt aaaggcaatc
    37501 gttgaaccat ggaaaagttc caaattgtat tgcccatcta atttcactaa tggtgcaata
    37561 gctggagtat caaatttgct atcgtaggca ttgttgatac agtagtccaa ctcctcagct
    37621 gtaaagtcat ctaaaaatgc tgacaaaact agcttagcaa cttcctggta agaagtatct
    37681 ttcaatttgt caaagtccaa atctaccttt ggataagtaa ccggtgtaaa caaaccgccg
    37741 tccgtcgcca aaccttgcaa aattgcttgg ctagcagtta ctgtattgtt ggcatcacgc
    37801 gttgattgat aaactaatgt cattactctc tatcctttat ctatagtctc gtccattata
    37861 tcatgatttt tcagaaaatt ctccctttat aagagaaatt ataggctcaa ttcttctctc
    37921 aaaggctgta aataggtcat ttcttcctta tttctcacca ctagtccctc ctcagctagt
    37981 aggagtaagt ctttggaaaa ttcaataatc gtagtttctt cctcatctgt aagatttttc
    38041 ttagaaaatt gtctccttaa agacttgtaa tcataaccaa atactttaaa gaaaggtgct
    38101 gtttctaagt aagcttctaa cttgtctaaa ttaaccaata atcccaagtg aaaagctgca
    38161 gaagcaaaag tcctatcaag tggctgtgta cacacactac gaaactcaac tgttcctcga
    38221 gtcgttaagt cttggtactg gtaactacga tgagtttcaa aatccttctc ttggggggaa
    38281 ataataacct catccccatt cagagcaaat gcttggattt caggcgtagc caaatagtcc
    38341 ccagcctgaa taggataaaa ataataggtc tgcccatcac gttccgcagt aaaaatcgca
    38401 gaatgattta gatagtcaaa aaaatcagct tcatcattaa ggagtctagc attgacccca
    38461 acattctctg gatagatacc atgcatagat tcttcccaga aaatatccct tgaaattttc
    38521 gtatcccaat ccgcacccga aaattcagag tttgcaaata aataagcctt agccgcttca
    38581 atttgagtaa aagcattaat cacccgtaag tagttggttt ttgaaatatc cagctgaacc
    38641 tggctcccac agataaaagt accatattca gggaaatgat gtaaatctga tttaataata
    38701 tttctactca aattcaaata atccatcaac atctgatagc gtggataagc cactggacaa
    38761 ttctcatttt tatcccagtt gggatggata ccacagccaa caatagcatg atttgattca
    38821 gctaactttc tctgaattac attcatataa ttattgaaac gattttcgac ctcttgaatc
    38881 gtttcagcct taccaaatgc aaactcaatc gttgtatagg aaacttcaaa taaaatagca
    38941 tcctgactta tcggatctac taactggatc agattgccaa aatcatctac ctttgctacg
    39001 gtgagatcca aagtagaaac taaataatga aatagatcct ttataacttc aacatctgta
    39061 gcatcccctt ctaaacttgc aacaggatac tccaactcaa ttccgacaaa caattcagga
    39121 ttttctttaa tatttttcaa ataccgatgt tttaataaat cgatagaaca agacatacta
    39181 ccctacactt tcttaatcta aataaaattt gaataactat aattatacca aaaataatat
    39241 aaaaaaagaa cgaagaataa caacgttcct aacactatac tataccggcg gccggggtcg
    39301 aaccggcacg tccttgcgga cactggattt tgagagcagt gaaattagca gacttacgtc
    39361 ataattcaga ttaattcaat gttttaagaa attagttata ctataaaaac aataattatt
    39421 ttagttttta gtaatttttt aggaattcct atcttggatt tgatgcctta tttctttact
    39481 taaatttttt aggtcttcac cattacatag tttttctcca atgagtttac taaaggtaaa
    39541 agacttaata actttcttga gactttcttc aaacttgcca tttagaagct tcaaatagct
    39601 ttcaaaatct gatatcactc tcgttttgac ggtctcaaag tcttcgtctt cagtaatttc
    39661 ataattgact gatatccaat atagcatttt ctatctcctt atttagtttt attattacta
    39721 gtttattata tttttaatag aatgtcgcaa tttaattata tagaatttaa attcaaaaat
    39781 attgttgaca aatagaaaat actgtgttaa aatgtctata taacagagac agttggaggt
    39841 ataagaatga gtcgtactta tataaatata agacttgcat acgaaaccaa gtattggtta
    39901 gaatgtatac aagaagaggt tcaaaaaaaa ttagatgctt taattaatga acaagatata
    39961 gaggagttag aatcaatcat cactaataag ttagaaaaaa aagattctct attgggggct
    40021 gtttccataa caactttttt caaggtatct tcttcaagcg tgattgaaaa agcctataac
    40081 gagacaaaaa attacactac ttcagaatgg cgagaaattg caaggcaaat gaatttggca
    40141 aaagttaagc aaaacatgga aattgggacg ttaacaccta gattatattt agataataat
    40201 attatttcag aattagagaa gtatcaattt ttattcaaaa gtgatgatat gataaggcag
    40261 gtaaggatga gctatgttat taaaatggtc gcatttgcct actataaaaa attgtttgca
    40321 tgatttataa gctcgataat aagagcttat aaaaatacaa cctttgtctg tgttaacgag
    40381 acttttaaac tttttaatcg gaaggagaat attttgatag gagcgtcacc tattatttat
    40441 ttgacaacat taaataaaaa ctaatattaa aaaaatataa aggaggagca gaaatgccaa
    40501 aattattaga gactgaaaaa tacagtttag atagcattat agatggaggg aagcttagaa
    40561 tgatttctaa gttttgccca gacttacatg gcttgaggta cgaattcaaa acatcagact
    40621 caattactaa agaatattgt aaaaaaatac gtcaagcttt aagagattct gatccagaag
    40681 gaaagagtgg aaaaaaatgt atgatgagat atacaataga tattttaaat gtatggaaca
    40741 cgctatgtag aacacgagat tttataacgg ggagtttaaa agcggatgat gttatagatg
    40801 ggaagacagg gatatacttc tttgatgtta atacgtctaa tgtaattacg gatgatgtta
    40861 tagaaaatgt taaaattaat cacaaaagct tagtacgaaa tgttgatgaa gaaaatatag
    40921 aaagtatttc aaaagaaatt cctaaaggta ctgatatgta ttattatgtt ttgtatagat
    40981 tagggttgaa taggattaag tataattatt tagtcaaggc tctggcaggc gcaatacaga
    41041 aggattaaga atataattat ataattaagg gggagttttt tctcccctta tagagatagt
    41101 attattcttt tggtatttgg ggtatcgttt atcaatctca tcttatagct aataaaaata
    41161 gtctatgttt ttagtgaaaa aaatattatt ttaaggagtg gtgatatgta tatacttgtc
    41221 acaaatggga aaagctacgt gactttccct tggttgcgtg aaatagcttg cagaaattat
    41281 aaaggagaaa ctaaggtgtt tactacaaag gaactctata atttcctata ttaaacgctt
    41341 taactatcac atttttaata ccaagaaaag taaattaaaa tatatagcag tattagagag
    41401 gcaaaaacgt aaagcatggc atagtcatat tttgctattc agtgttccct atattccaca
    41461 taagcaatta ttagaacttt gggggcatgg agcagtacgg ataaataaag ttgacgttga
    41521 cagcaaagaa aatcgcggtc gatatgtcac aaagtatttt gaaaaaggta ttggacaaga
    41581 attgttggaa aacttcggaa agcaagccta tttttcatca cgcaacttga aaaagcctga
    41641 tgaagataaa ttttacactt atgaagattt taactatgat agttcagtcg tactatatga
    41701 aacggaatac aactgataac ccgaggcttt acagtctatc agaacaagcg aattggtact
    41761 atacctgcta ctattgctac cgaattactc ggttttgatg ttcaaaacag taccctcaag
    41821 gagtaaaata tggcaattag aaaaggtaaa gacggtaatt gggtagttga tattagcaac
    41881 ggttttgacc caataacact aaagcaacgt agacttgtca gaaagggata tatgacgaaa
    41941 aaagaagcta ttgaagcaga acactactta cgaagtgtag agttaaaaga acgcttctat
    42001 ggggctaaaa taactatctc catactatat gaactactta aggaagaaga tagcataaat
    42061 catcgaaaag caagctatat caatacacaa gataataatt acaacaaaca catcaaagat
    42121 tatttttcta tggtcgataa tgtcggaaaa ctaacctatg aagacatcta ccaatttaga
    42181 gaacatctta ggcaaaaagt agctaaaaat tctgataaac cgttaagcac aaatactatt
    42241 aacaaaatca tgattttact caaaaaaatt tttgatgttg gtttgcgaaa aggctattac
    42301 tcctccaatc cagcaaaatt gataaaaaag ttgccaattg aaaaaacaaa aatgcaattt
    42361 tggacagtca aagaatttca gaagtttttg acactatttg aacccgaaga atacaatatc
    42421 aaactactct ttactgttct attctttaca ggattaagac ttggggaagc tcttgctcta
    42481 acatggcaag acatcgactt ttcaagtaat acaattcata tcacgaaatc tgtctatgtt
    42541 aataaaggag taactcatat cagcacaaca aaaactaaag caggaacaag aagaattgtt
    42601 atcaataaaa aattaagcca agaattacaa gattgggaaa agcgacaaaa acatctatta
    42661 gagcaattta ccaacaatag cctaacatta caagtgtttc aaaatagtcc tatcacaatt
    42721 acaaaaaatg ctattgaaaa gcagtacaag aaaatcattg aacgtgatag tacactaaaa
    42781 aagatacgca tacacgattt taggcactca cacgcttccc tgctgattaa ccaaggggaa
    42841 gattatctag ttgtaaaaga gcgactagga catgcttcta taacaaccac gattgatacc
    42901 tactctcact tgtacccaag taagcaaaag gatttagctg ataaactaga tgatttacta
    42961 taaagtaatt gagttttata aatggaaagt ttataattaa atcatggata catcacaagt
    43021 aataaaagca catgaagtag ctaaaaaagc acactttgga caaattgata gagcaggaat
    43081 tgactacatt aaacaccctg aaacagtagc tagttttgtc acaactgatg aagagaaagc
    43141 tgtcgcctat ctacatgatg taattgaaga tactacacta accctactag acctaaaaaa
    43201 ggaaggtttt tcaaaaaaca ttatagaagc agtcgatata ctcacaaaga aaaaaggaca
    43261 agattatcaa tcttatctca atctagtaaa gacaaatgaa cttgctagag ttgtaaaatt
    43321 ggcggattta cggcataatt cagatttaac cagactacca ttaattactg aaaaagactt
    43381 agagagaaat aagaaataca gttctgctat tagattttta agaacaaaga aaaaaagtta
    43441 gtaactaaac tataaaaatt tataaagaga aaacaaggct tataaacttt gtctttatta
    43501 ctatcttggc ggtcagtctc gaactggcac atccttgcag atactacaat tttattaaaa
    43561 taaatactat acaaagtgaa attttttatt gagaaacttt tagactagga gtataatgta
    43621 tctaaaataa ctattaggtg gctgttatat gaataatgtt gttactacac taatttctgt
    43681 tcaatttagt caagagttaa attctttatt aaatgctatt gttgaagaaa ataatacaac
    43741 aaagactgac tttattagac aagctgttat agagaaaatt gaagatatgt atgatattaa
    43801 ggtcgctgat gaagcttata aaaaatgggt tgaatgtggc aaaaaaacta tctcacatga
    43861 agaaatgatg agacgctatg gctaaaatat acgcaatatc tgatatacat ggatacttgg
    43921 atgaattcat agacgctctc aataaagtaa atttaaacga taaagataat cgcctatttt
    43981 tactaggaga ttatcttgat aatggacttc aatcttttca agtcatttcc aaaataatcg
    44041 aacttgagga gatttatcct aatcaaatta ttactcttct agggaaccat gaagaatggt
    44101 tttatgattg gttgatttta gataagccta ctgcttcagc atttccagaa acaataaaaa
    44161 gcttcttctc tccagaggaa ttgaactata tttttaaatc gaatgctaac aactttgaaa
    44221 caggtgttag aaatgaaatt aaaaataata tcaaattcaa cccatttata aactggttta
    44281 aaaagcgata tagggataaa cgctattatg aaactgatac ccaaattttt gttcatgcag
    44341 gcattgatga agaagcagga atgctttgga aagaactaac gagttcaaag atatttacaa
    44401 acaaatttcc aattaccact ggtagatttc ataaagctat tatttcgggc catattgctt
    44461 cttgggaagt agctaaagat agaagatacc taggtaagat ttactatgat agtaaaagtc
    44521 attacttaat tgatggagat gtaacgaata gcaaaacaat acctgttctt tgctatgata
    44581 caattaccca aaaatatcac tttctataac ttttagtcat gtgcttttat atgaaattag
    44641 taattattag taacaattcc aagaaatttc ttatgacata acaaaaagac aaggcttaga
    44701 aaccttgtct tttcaactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac
    44761 tggattttga gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta
    44821 gctggattcg aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac
    44881 cccaataata taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat
    44941 ctggtgtgtt aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat
    45001 tgaacccaca ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat
    45061 ggaaggggag ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt
    45121 agcctcttcg ctacccttcc aaaatatata aatggcgcga gacggaatcg aaccgccgac
    45181 acatggagct tcaatccatt gctctaccaa ctgagctacc gagccttatt gcgggagcag
    45241 gatttgaacc tacgaccttc gggttatgag cccgacgagc taccgagctg ctccatcccg
    45301 cgttaatata aaaggaggat gtgggattcg aacccacgca cgcttttaca cgcctgacgg
    45361 ttttcaagac cgttcccttc agccggactt gggtaatcct ccaaaatagt ttatacggga
    45421 acaagcccgt gtcctcttag tgaacagata atattccaat cccctagtaa tggactaaac
    45481 actatgggca cgagtggact cgaaccaccg acctcacgct tatcaggcgt gcgctctaac
    45541 cacctgagct acgcgcccaa gttaaaaact tggtacaaag aacaaagttc aaagcgggtg
    45601 acgagaatcg aactcgcgac aacagcttgg aaggctgtag ttttaccact aaactacacc
    45661 cgctaaa
//
LOCUS       DAVMCG010000013        45657 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVMCG010000013 DAVMCG010000000
VERSION     DAVMCG010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45657
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.013"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(442..2169)
                     /gene="ezrA"
                     /locus_tag="VYP66_000876"
     CDS             complement(442..2169)
                     /gene="ezrA"
                     /locus_tag="VYP66_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1850449.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2251..4197)
                     /gene="gyrB"
                     /locus_tag="VYP66_000877"
     CDS             complement(2251..4197)
                     /gene="gyrB"
                     /locus_tag="VYP66_000877"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1850450.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKREG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4212..4775)
                     /locus_tag="VYP66_000878"
     CDS             complement(4212..4775)
                     /locus_tag="VYP66_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1850451.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4860..5414)
                     /locus_tag="VYP66_000879"
     CDS             complement(4860..5414)
                     /locus_tag="VYP66_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1850452.1"
                     /translation="MVKVAVILAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5425..6648)
                     /locus_tag="VYP66_000880"
     CDS             complement(5425..6648)
                     /locus_tag="VYP66_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1850453.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6685..9135)
                     /locus_tag="VYP66_000881"
     CDS             complement(6685..9135)
                     /locus_tag="VYP66_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1850454.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9335..10264)
                     /locus_tag="VYP66_000882"
     CDS             complement(9335..10264)
                     /locus_tag="VYP66_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1850455.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10404..10691
                     /locus_tag="VYP66_000883"
     CDS             10404..10691
                     /locus_tag="VYP66_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1850456.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10725..12059)
                     /gene="ciaH"
                     /locus_tag="VYP66_000884"
     CDS             complement(10725..12059)
                     /gene="ciaH"
                     /locus_tag="VYP66_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1850457.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12049..12723)
                     /gene="ciaR"
                     /locus_tag="VYP66_000885"
     CDS             complement(12049..12723)
                     /gene="ciaR"
                     /locus_tag="VYP66_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1850458.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12832..15378)
                     /locus_tag="VYP66_000886"
     CDS             complement(12832..15378)
                     /locus_tag="VYP66_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1850459.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFFAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVTSQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLTAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15501..15941)
                     /locus_tag="VYP66_000887"
     CDS             complement(15501..15941)
                     /locus_tag="VYP66_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1850460.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(15916..16785)
                     /locus_tag="VYP66_000888"
     CDS             complement(15916..16785)
                     /locus_tag="VYP66_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1850461.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16763..17263)
                     /locus_tag="VYP66_000889"
     CDS             complement(16763..17263)
                     /locus_tag="VYP66_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1850462.1"
                     /translation="MEIKKHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETRFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17274..17972)
                     /locus_tag="VYP66_000890"
     CDS             complement(17274..17972)
                     /locus_tag="VYP66_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1850463.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(17965..18201)
                     /locus_tag="VYP66_000891"
     CDS             complement(17965..18201)
                     /locus_tag="VYP66_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1850464.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18301..19227)
                     /locus_tag="VYP66_000892"
     CDS             complement(18301..19227)
                     /locus_tag="VYP66_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1850465.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19302..20117)
                     /locus_tag="VYP66_000893"
     CDS             complement(19302..20117)
                     /locus_tag="VYP66_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850466.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20121..20441)
                     /locus_tag="VYP66_000894"
     CDS             complement(20121..20441)
                     /locus_tag="VYP66_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1850467.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20693..20773)
                     /locus_tag="VYP66_000895"
                     /pseudo
     CDS             complement(20693..20773)
                     /locus_tag="VYP66_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(20817..22814)
                     /gene="metG"
                     /locus_tag="VYP66_000896"
     CDS             complement(20817..22814)
                     /gene="metG"
                     /locus_tag="VYP66_000896"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1850468.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFCLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(22938..24197)
                     /locus_tag="VYP66_000897"
     CDS             complement(22938..24197)
                     /locus_tag="VYP66_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850469.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24199..24900)
                     /locus_tag="VYP66_000898"
     CDS             complement(24199..24900)
                     /locus_tag="VYP66_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850470.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(24884..26083)
                     /locus_tag="VYP66_000899"
     CDS             complement(24884..26083)
                     /locus_tag="VYP66_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1850471.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVANEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26369..27715
                     /gene="gor"
                     /locus_tag="VYP66_000900"
     CDS             26369..27715
                     /gene="gor"
                     /locus_tag="VYP66_000900"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1850472.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            27911..28447
                     /locus_tag="VYP66_000901"
     CDS             27911..28447
                     /locus_tag="VYP66_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1850473.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQTYFTN"
     gene            28503..28583
                     /locus_tag="VYP66_000902"
                     /pseudo
     CDS             28503..28583
                     /locus_tag="VYP66_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(28652..28867)
                     /locus_tag="VYP66_000903"
     CDS             complement(28652..28867)
                     /locus_tag="VYP66_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1850474.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            28965..29285
                     /locus_tag="VYP66_000904"
     CDS             28965..29285
                     /locus_tag="VYP66_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850475.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29315..29653)
                     /locus_tag="VYP66_000905"
     CDS             complement(29315..29653)
                     /locus_tag="VYP66_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850476.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29665..30384)
                     /gene="trmD"
                     /locus_tag="VYP66_000906"
     CDS             complement(29665..30384)
                     /gene="trmD"
                     /locus_tag="VYP66_000906"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1850477.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30374..30892)
                     /gene="rimM"
                     /locus_tag="VYP66_000907"
     CDS             complement(30374..30892)
                     /gene="rimM"
                     /locus_tag="VYP66_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1850478.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(30923..31711)
                     /locus_tag="VYP66_000908"
     CDS             complement(30923..31711)
                     /locus_tag="VYP66_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1850479.1"
                     /translation="MKRFEVSTEIGSLSVAYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIYDQAGKNLDNLADVVYEALEELGISEYILCVHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPIFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(31815..32058)
                     /locus_tag="VYP66_000909"
                     /pseudo
     CDS             complement(31815..32058)
                     /locus_tag="VYP66_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(32288..32527)
                     /locus_tag="VYP66_000910"
     CDS             complement(32288..32527)
                     /locus_tag="VYP66_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1850480.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32547..32819)
                     /gene="rpsP"
                     /locus_tag="VYP66_000911"
     CDS             complement(32547..32819)
                     /gene="rpsP"
                     /locus_tag="VYP66_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1850481.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLTWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            32989..33198
                     /locus_tag="VYP66_000912"
     CDS             32989..33198
                     /locus_tag="VYP66_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850482.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33677..33868
                     /locus_tag="VYP66_000913"
     CDS             33677..33868
                     /locus_tag="VYP66_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850483.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDF"
     gene            33982..34785
                     /locus_tag="VYP66_000914"
     CDS             33982..34785
                     /locus_tag="VYP66_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1850484.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34841..36382)
                     /locus_tag="VYP66_000915"
     CDS             complement(34841..36382)
                     /locus_tag="VYP66_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1850485.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHDPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36384..36866)
                     /locus_tag="VYP66_000916"
     CDS             complement(36384..36866)
                     /locus_tag="VYP66_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1850486.1"
                     /translation="MVKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            complement(36866..37951)
                     /gene="rlmN"
                     /locus_tag="VYP66_000917"
     CDS             complement(36866..37951)
                     /gene="rlmN"
                     /locus_tag="VYP66_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1850487.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCSSGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LTELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(37972..38502)
                     /locus_tag="VYP66_000918"
     CDS             complement(37972..38502)
                     /locus_tag="VYP66_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1850488.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(38659..39264)
                     /locus_tag="VYP66_000919"
     CDS             complement(38659..39264)
                     /locus_tag="VYP66_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1850489.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39437..40474)
                     /locus_tag="VYP66_000920"
     CDS             complement(39437..40474)
                     /locus_tag="VYP66_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1850490.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40508..41443)
                     /locus_tag="VYP66_000921"
     CDS             complement(40508..41443)
                     /locus_tag="VYP66_000921"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1850491.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(41996..43186)
                     /locus_tag="VYP66_000922"
     CDS             complement(41996..43186)
                     /locus_tag="VYP66_000922"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1850492.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43401..44744)
                     /locus_tag="VYP66_000923"
     CDS             complement(43401..44744)
                     /locus_tag="VYP66_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1850493.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45124..45636)
                     /locus_tag="VYP66_000924"
     CDS             complement(45124..45636)
                     /locus_tag="VYP66_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1850494.1"
                     /translation="MPAEVLSLLPQSGTYTTSSSVAIAFVPEAPMPVEVAVANGTWTF
                     LGYQEVEEGSNLTFVGKWVFEAKQDPSPQPQPAPTPQPAPQPNPVPPVNPGGEQGTDN
                     NQADRHQSEQPRKPEENPPAQGPAGEKEKQATLPNAGSTAPLSLTGLVTSSLLAGLAV
                     LLLGRKRKDD"
BASE COUNT        13508 a         9969 c         8262 g        13918 t
ORIGIN      
        1 tcgtaaacaa agaggtttta gaggcctatt taccgtggga ctaaagttgt acaagaaaag
       61 tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt
      121 caatagactt cgttattgga cggttaccaa gttactcaaa gtacagattt gaagctgcag
      181 ataagactga cgaaatcact ttaatactaa atgaaaatca aaaagcaaac taagaagcta
      241 gcctcaggct gtacttgagt acggtaaggc gacgctgacg tgatttgaag agattttcga
      301 agagtataaa acactgtttt gaggtggtgg ataaatcggc tgggtaaaaa ctcaatctca
      361 ggagaaaatg aagtaaatct ccccacaact atagaaaaag atttgattct gctcctcaca
      421 caataaaatc tttttctttt attaaaaacg aatcgtttca cgtgttttct catatgaggt
      481 aacaaagcga ttggttacac caggctctgc cacttccaat gcttgagaaa tcttgtcaaa
      541 tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa atgcttcttg
      601 aatgcgttca tcaaatgagc gatagcggtt agaatattgc aagagttgct ctgtcaaagt
      661 tgcatattgt acaatattat aagtttccgt ttctaaagct tccatatcat tcgttgcaat
      721 ttcaagaact cgggtaacag attcaatgtt aatcattttt tgttctaact caaccattaa
      781 atcctcggta ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg gaatacctgg
      841 cagattgcgt ttttccatgt atcgcttgat agtatggaga cgattgacat aaacattggc
      901 cttttgacgt gcattaatat catctttctc aatttgtgtc aggcgctcac taactgaaat
      961 ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt cttcaagaac
     1021 tgaataagct tgggttggtt cttcttgatt cgaagttacc tcaacaatag ctgcctcaaa
     1081 actctctaat tctgtctgaa tacgacgaac atggcttgca gctgtctcag gaagtaaata
     1141 ggtcttgttc aaacgtgcaa tatcttctcc caataaagta ttattctctt tcatatgttg
     1201 aaggtaagtt ggaagagttg caagtagatt ttccactact ttctgagcag caatttctcg
     1261 agtaaaaata tcatacaagg cattgatttc ctcttgtgcc tgtccattct catattcggc
     1321 attatccaat tccaactgac gaatattctc ttggtttttc ttgaatgctt cataaagcaa
     1381 gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa ttagtttacg
     1441 ataaccggct tccaaatcct gtaattgatc tggcaattct gtagaaagcg tcgtaaccaa
     1501 ggctggaaca cgatccacaa tatgacttaa ggccaaaatg tgattttctg tattatccaa
     1561 aatcactgcg gcttccacag ggtcacccga tgaattcaag gttacaaatt gtgaaaattc
     1621 agattggata ttttctaatt gtttttcaat ttcatccaag gcttgaccat actgttctga
     1681 attttcagca actctatgct gaagttcctc aaataaatcc aaagcatgaa gaacacgacc
     1741 actattttta gattcttgct tctctaagtc tgccaaagca ttgcgaattg ccgcaatatc
     1801 ttcttcaatc aaagtaattt gactctcaat ttggtcaatt tgatgactgg ccttgagaaa
     1861 acgaaatgaa tggttatagc cttctgcttc aaagagatta ttttcaatat cggcaaaaga
     1921 gttgagagat aaatcgaccc atttttgatt ccattcacgg aaagccactt gactttgtcc
     1981 aatcaagtgc atatttttta cagcttctac ttcatcattt actggaagat tgtatagttc
     2041 ttcttttctt tcttctagcg cctctaatct cccctcgttt cgcttacgta gaaagattgc
     2101 cactacataa gccagaacta aaatgactgc aattgcaacc attaaataaa ttagttgtcc
     2161 attagacata tcaaactcct tttttacttg aaacaatcgt aacgattata tcatattttt
     2221 tagaccaagg gaactacttc tccctatttt ttagacatca agtgtactat agacagcatt
     2281 ttcttcgata aactcacgac gaggctctac tcgatccccc atcaacatat caaagatttt
     2341 atctgcttct gcagcatcat ctacagaaac tctagccatc aagcgatgtt cgggatccat
     2401 ggttgtttcc cacagctgat gatcgtccat ttcacctagc cccttataac gctgaatagt
     2461 cggtttggta cgaccttcac tataacgggc taaagcttct tggagtttga tttcttgatc
     2521 tgcacccggc tggatatatt ctttaatctc gcttccaacc ttgacaccat agattggtgg
     2581 ttgggcaata taaacataac cagcttctag gattggtttc atataacgat aaatcaaggt
     2641 taaaagaagg gtacgaatgt gggctccatc gacatcggca tcggtcatca aaacgagttt
     2701 ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat cctgttccca tggctgtgaa
     2761 aagactacga atttcttcgt tagctagaat cttatccata cttgcttttt caacgttcaa
     2821 aatcttaccg cgaattggaa ggatagcctg aaactcacgg ttacgaccag atttggctga
     2881 tccaccagct gagtctcctt cgacgatgaa gagttctgtt tcagcagggt tattagaaga
     2941 acagtctgct agtttccctg gaaggttgga aatttccaaa ccagattttt tacgtgtgac
     3001 ttcacgcgca cgcttggcag ccacacgagc cttggcagct aaaatccctt tttccacgat
     3061 acgtttggca atctgtggat tttccatgag gaaatcggag aaggcttcac tgaagaggcg
     3121 attggtaatc ttgaccactt cgctatttcc caatttggtc ttggtttgtc cttcaaactg
     3181 tggatttggg tgtttaactg agataactgc agttaagcct tcgcgaacat cttcccctgt
     3241 taggttgtct tcattgtctt tcagtaactt atttttacga gcataatcat tgataacacg
     3301 tgtcaaggct gtacggaaac cttgttcatg cgttccacct tcatgtgtat gaatattatt
     3361 ggcgaaactc atgacatttt catggtaacc agttgtgtac tgcatggcta cctcaactgt
     3421 gatatcatcc atctcaccgt ctgtatagat tggtgtatca aagattacat ccttgttctc
     3481 gttgatatat tcaacgtaac tagcaatccc accttcataa tgataatgct tggtttgttc
     3541 caaaccttca cgcttatctg taattgaaat ttgaagaccg cgatttagaa aggccaactc
     3601 ttgaatccgt ttatttaatt tatcaaaatc aaagattgtt gtttcagtga agatttttgg
     3661 gtccggtgtg aagtgaacag ttgttcctgt tttatccgta tctccaacta tttcaagatc
     3721 tgcgacaaca tgaccacgac ggtattcttg gtaatgaatc ttaccatttt tgtgaacatg
     3781 aacgtctaat tgagtggaaa gggcattaac tactgacgac cccaccccgt gaagaccacc
     3841 tgaaaccttg tatccaccac cgccgaactt tcctccagcg tgaaggactg taaagacggt
     3901 ctcaacagca ggacggcctg ttttttcctg aatatcgact gggataccac gcccatcatc
     3961 cacaacagta atcgaatcat ctggctcaat aaaaacttga atatggctgg caaatcctgc
     4021 caaggcctcg tcaattgagt tatcaacaat ttcccagact agatggtgaa gaccttcttt
     4081 tgaggttgat ccaatgtaca tccctggacg catacgaaca gcctctaagc cctctaaaac
     4141 ttgaatttga ctggcatcat aatcctgtgc ctgcagattt ttgatttctt ctgtcatctt
     4201 attccttttt cttatatgtc taatacttgt cttaaattca cgatactggt aaacaagtgg
     4261 gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg gccgatcacc aatgacaaga
     4321 ccagagctaa tctgatactt ttctcttaaa taaagcatgg attcgggatt tggctttctc
     4381 ttaaagcctg agctagaagt caccacttct gtaaaataag ctgctataga ggttttttct
     4441 aaaatttcca aaacctgatc atttcgatga gagaccaaaa aatgacggcc accttgattt
     4501 gaaatgactt ccaataggtc agaaactcct tcaaataaaa tcgggtgttc aagctctctg
     4561 gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa tgtctcaatc
     4621 gcaaaaggag tagaaacctt taaagcttga tagacactgt catggtcttg tgtgatacca
     4681 tacagtgcca atgtttcaac aaatgcagct gttgaagttt cataattatc cagtaaagtt
     4741 ccacctaaat cccagatgta atcgtgatat ttcataccct tcattatagc atttttttat
     4801 gaaaaaagcg atgatttccc tgagttttcc acataaaaaa cgagagaata actcccgttt
     4861 tactgatttt taccaaagac atcttgatag agcattcctg ttcgtaaact ctctgcgtcc
     4921 cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg accccgactg
     4981 gttgtcaact gaccatctac cactactgtt tccttgacat agtgaccatc aaggatttgc
     5041 tcttgaacgc cgtcataaca agtgtatcgc ttatttttca atatctctgc ttgattgagg
     5101 gcaattggtg ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa gctttgcaat
     5161 tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac caggcatacc tccaggaaga
     5221 acaatcatat catagtctga taaatctcca tcaaagacat gatctgctct tacttggatt
     5281 gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat attggctcga
     5341 cgcaagacat ctacaactgt caaggcttca atttcttcaa agccctgagc taatataact
     5401 gctactttta ccatgatttt ctccttattt aatttgtttt aatacaacct ttttccgttt
     5461 gaatggaact tttccgctct tttcttcagc tagattagtc tggtaactca tcgataaaag
     5521 caaaccaaca ccaatcagat tactgataat agctgatccc ccttgcgaaa tgaaaggcaa
     5581 gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg atattctcaa agatgtggaa
     5641 gagcaacatc ataatcaaac ctgtggaaat ataagtgtag aactggttat ttgatttaag
     5701 agtaatcttc aacatacggt aaatcaacat gagatagagg gcaataacca ggacagagcc
     5761 aataaagcca aaatcttctg caataaccgt aaaaatcata tctgactctc gaactgggat
     5821 aagcagattc gaagcattaa atccctgacc aaataagcca ccactcccaa tggcaatctg
     5881 cccttgagcc tgctggtaag tcgttgtttg ggcaaactca aagggattga gccaagccaa
     5941 aatccgattg atttggtagg tcggcattcc aatctggtga agaaaagctc gtccgtcctt
     6001 gctaataaag atagctaaga aaccagcaac tcctgttaca gcagtcacaa atactgggat
     6061 aataattttc caagaaaccc ctgataataa aacgattcct gagaaaatgg ctacaaaaac
     6121 caaagccgtc cccaagtcac tttgaagtgc taaaagaact aggactggaa tggtaaagag
     6181 aatcatccag aaaattaaca aaaagtccag cggaaccgtg cgtctccatt ccttatgttt
     6241 ctttgtaaat tggacaatga cacgagccaa catgaggata taggatatct tcataaattc
     6301 tgacggttgg aatagggtaa ttccatttat tgatacccag tttttggcac ccgttgatgc
     6361 aactaagctt ggattataaa atacaatcgg caagatcata agtcccaagc ctaaaatata
     6421 tagaaagggg gtcaccttcc aaagaaattc tgtattaaag agcatgacca caaaaccaat
     6481 cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa atgggcagaa tattattggg
     6541 gtaatcatga ctaacggcta tatagatagc caccacaccg atgaccagta gaaaaaatac
     6601 tggcaagagc aaactgtaat cgactcttga gtcgagagaa cgtttcatat atactaacct
     6661 tatactttca tacaatacta tttatcaaag ttcattaaaa aatctatcaa tagcctcgtc
     6721 aacttcggat cgagagatgg ttttaacagt cgcttcttct gctagagatg ctactatttg
     6781 tttgccgtat cgttttccga cgattctcct atccaaaata agagttaagg aacgttgata
     6841 ttcacgtctc atacttcttc ccaaagcctg ttttaaacga ataatggcca ttggcaattg
     6901 ataatcataa aaggcatttt tcccttcttg attcagttct tgattaatct ttttcgtcaa
     6961 gggttcttga ggattttgga aaggaagcct cggtacaact tgaatcacaa aaggatggct
     7021 tgaaaaatca actccctccc agaaacttgc tgcaccaagc aagatttgtt gttcaccttt
     7081 ttcaaagcgt ttctttagct gatgaacatc cccattttta tactgggcca agtggctaac
     7141 tgtaagtaaa tccgatactg ctagaagcat gtctttagcg gtaaagagaa ccaaaatcgg
     7201 ttgctggaaa gcttgaattt ccactagtaa agcagctacc tctctggcat agacttctaa
     7261 ggaggtttct gttaccagag ggaaatcttt gaccatgacc acttcttgtt cctgttttcc
     7321 ccgagattca atcttgacaa atttagcttc aggatagcct aaaaggtctg ccaaagaaac
     7381 cctctgacta atctcaagag tagccgatac tcccaggact tggcaactct caggaagtaa
     7441 agaggacaga agagtacggc ctgattttgt agaagaaatc tgaattttct tttgactcgt
     7501 ttcagttact tcaagccagt aatcaccttc agctgtaaaa tagcgaacca gctcatcaaa
     7561 gccttctact tctaattctg aaaaatactg atggagatta tccagagaat ctaagatatt
     7621 tttcctagat ttgccagact gaaattgttc tatcaagtag agacactcaa agcgaatact
     7681 ttctagtatc cgttgttgaa ccctgttttc ttctcctact aaagccttat caattaaatc
     7741 gataatagat tgtatatcgt aggtctcttg aagcagattt tctagagcta acaaaatctt
     7801 ttggacttca tcaataatca gtaaacggtc actgacaaat tcaggattat cttcaagtct
     7861 ggtcacgaga taggcatgat tagtcactaa aagcttgcaa gtctctgccc tttcttgact
     7921 acgtttccaa aaatcttccg tcacaaataa gctatgggat gataaattcc catcatgacg
     7981 aaggtctgct agaaaatgtt ggtaacggta gagttgcccg atttcatcca aatctcctgt
     8041 ctctgtctca gtaagccaga ccaagacttg cattttaaag cgtctaaata agcgattttc
     8101 atcattttcc tgcaaggaat gataaaaggc atccaacttc agataatttt gtggtccctt
     8161 taagctatga atatctgtat ggaacacttc cttgagacgt ttaccttctt cttccatgat
     8221 ttgattttga agaatctttg tcggaacact aagaacaatt tgtcgctctt tggattgaga
     8281 taaagcgggt aagagatagc cataggtttt cccaatccct gtcggcgctt gaatcagaga
     8341 gacaggttca tctttcaata gcaagccaac ctctttagca aaactttctt gttcctccct
     8401 cacttcaagg ttcaacagag aaatattttt agaaaagtct tgagatagtt ttcgtagctc
     8461 cagagaagct gccgttttct taaaatacag accttgaact tggaccaagt ctggagaact
     8521 caggatagat tggttgcgat aagtttcctc aataaccagg taggactcat ataggagagc
     8581 gtcagccatt tccagcaagc gttccaagag acctttagga agctgggtca tcttttcccg
     8641 taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa agggctgtgt gtgcgtgttt
     8701 aagaggaatt cctaattctc gacacaaaat cggcaagcta tatttttcca gttcagggaa
     8761 aaagacctgg gccaattcga ccgtatcaac acgagggttt cttagctcat agccttcaaa
     8821 aaataaattt tccgccaaga gattagcatc aaactgaaca ttatgggcta caaaaatccc
     8881 atcctccacc aagtcaaaga tttttctggc aacttgcgaa aaatcaggtg cttgcgccag
     8941 acgttggtct gtcaatcctg tcagttcttt gatatgagca tccaagggtt catgtggatt
     9001 gacatccgtc gtatagtgat cgacgatttc tccatcctca atcacgacaa ttcccacttg
     9061 gataatttta gccttactac ctgtgctagt tgcctctaaa tccaccacaa catagcgatt
     9121 accaatcgtt ttcattataa aaaattatac caaaaaaagg gccatttggc acctgcaaac
     9181 ataggataat tttcaaactc aagaacacta cttttcttag aaatcccatc gaatagagca
     9241 ttctagcctg ctgatttttt taaaatagtg aagaaatacg aaaaattgag agaagaaatg
     9301 ttttcatctt ccttctctca acgaatcatg tattttattt aaccatgtca ggatcgtagt
     9361 cataaaatcc tgtatcaagg aaacggtttt tagggtgaag tttacgaact tcttcatcca
     9421 gcaagaaggc ttggtcatgg ctaaagttgc cctcttgaat caagctacgc gcttggataa
     9481 agagttttgc aatctcaaca aagttctgac caggagtgta gagcccttct agtttccagc
     9541 gagtaaagcc atgctccacc aattctgtta atttgatcat caaatcaagg tcattgttgg
     9601 caaagatatg ggtcccatga ttatcttcaa aaatggaata gtggctctct ggatcacttg
     9661 gctcagccaa gaagaggtca cgtttatgcg tcttttcatc atcgatatgt gtaaagttat
     9721 agtagttttg caagagtgga cgtttagaat gatggatgac gctagcaccg taaaccaaaa
     9781 cttcagcagg aatttccaaa atctctggca ttttgaaaag ttcagctgat ggaatttcac
     9841 gcgccaaaac agcctcagat gcgccagcct tttgtcccca gaagttaatc tgacgactgc
     9901 tagttaccat ggttgaagca tcgtagatgg tcttaaatga ataaccatcg cggttaacta
     9961 cgtaaaagac gcctgcatcc ccaatcgtaa tatagtctgt cttgatttct tccaagaagt
    10021 ctaagaaagg cttgatacgg tccatcatat cttggtgcat gagagcattg accgcaacga
    10081 gcaattcctt accagcatca tgaaccaact tagcgatttc acgtaattgg tcataactaa
    10141 aggtcgttgg cagacgaagg ccaaaatctt tctcaccgac atagatacgg tctacgccag
    10201 cttcgagtag ttgttcaact tgttcaatac tttcagcagt tgctgtaatg acaatctttt
    10261 ccataagaaa aattatacca catttctcca aaatcatcca tgctttgaaa atgaaaaggg
    10321 actttattct ttttgtaacc tttctgtaat aattttctgc cgaaaaaatg ataaaatagg
    10381 tatgtactgt taaggagaga atcatgcccg taagaaaatt acaatcctat gaggtagact
    10441 atcaagaaga attaaaccag cagcttcctc attaccaagc ttatacacct gaagcgcaat
    10501 ctgatgccaa tctcaaggaa atcctatttt ttattaatat cgctgttttt tgtatctgta
    10561 ttgctatctt tagttttatc tttttagcat taaaattatc aactgctctt gcctttgccg
    10621 cagcaatcgg attcagctta cttgttttaa aagttcaacg gtctattatc aaacgaaaac
    10681 gtagaagata aatccaaaat atcgccccag ttggagcgat atttttattt tttcttttta
    10741 gatggtgtct gaatggcaat cttcacttca aagattgttc ccttgggttt attatctttg
    10801 acagtaacag ttccttttag agcatctaca atttgcttgg ctagggataa tcctaaacca
    10861 aaaccacctt tttgccgggt tctagctttg tctactcgat aaaaacggtc aaaaattttc
    10921 tttttatctt ctgtcgaaat accgattcca ttatcagaaa caagtaaata aagattgcga
    10981 tcggtcgccg agataagaaa atcaatttca ccatcctcct cagtatactt gacggcatta
    11041 tcgaaaagaa tggtcatcag ttgtttcaga agaagctgat ctgtgacaat tgttcgatgg
    11101 atacgatttt caaaacggaa gacacgatta ttttccgaag caatcatctc gtagtttgtg
    11161 aaagttgtat taaaaaagct agttggaact tctgcaagct ccggcttaat cccatcatct
    11221 ctccgagcta agttcagcaa gcttgtcgtt aaaaaacgca tatttcggac ttcttccaaa
    11281 ctcgatgcaa tgctttcgct cacatccata atggtagctt ctggcttacg aaaaagggtc
    11341 tctaagcgat tttgcaaaac tgcgagtgga gttcgtaact catgactggc attttccaca
    11401 aaagactgtt gcttctgcat actctcaagc aggggcctaa cactgaccct agctagatag
    11461 agactggcaa gtaaagacaa aatccagaaa ctagccatca cgaccacaat caattgctca
    11521 tgcttttgac tagcctgctc caactgactg gtattaatca agacagcagc atacttgata
    11581 ttggttgaaa ccgaactaat attggtctcc atcaaaatca cacgatagat ttcttcctgc
    11641 ccatagctat taaaaacctg aatctggtag atatgtccta gttctttctt ttctaactta
    11701 atcttatcca agcccaaaaa tcgatttcca gaaagaagtt gagtaaagtc tttatcaaag
    11761 agaatgactt ccgtattgga actgacatta ggttttattt ctactttact agcgtccgcc
    11821 ctagcatttt ctaaatcttt aatctcttct gttgccctat ttatagccag ctgaataact
    11881 gcttgaggat tttcactcag tccatgaagc ttatcgtcca ccgaagtata aagactcgaa
    11941 tgcatgactt gtaaaataat cagagtcatt gtagaaaaaa tcagggtgaa gacaccgaag
    12001 ttgcggataa aataactaaa gtcatccgca taccatgttt ttttaagttt actgaacatc
    12061 ttttaaaaga tacccaacac tacgcaaggt ttgcaaattc tctgcaaaag tggttccctt
    12121 taatttctta cggacttttg aaacatagac ttcgacaacc gaaatcgttg tatcactatc
    12181 aaatccccat agacggtcaa aaatctgcgt cttaggcaaa atcacatttt gattttgaag
    12241 gaaataaact agtaaatcga actctttccc cagcaattcg acaggagtat cttcaacttt
    12301 aacggtattg gttgataaat taaccacgat attcccataa gtcaaggtgt tttcattaaa
    12361 cttccctgaa cgtttgagaa gggcctgaat ccgcatttta agttcttcta ggtagaaagg
    12421 tttggtcaga taatcatccg ctcccagttc aaatccatgt cccttgtcat ccaaactttc
    12481 ctttgcagtc ataatcagaa ctggtgtcgt aattcccttt tcacgcaatt cttttaagac
    12541 ttggaaacca tttttttctg gcaacatcaa atccagcaaa atcaagtcat agacaccact
    12601 ctcagcttcg tagagacctt cttctccatc aaatacctgc ataacatccg caaaatcgtc
    12661 taaaaagtca aatactgaat ttgacagacc taggtcatcc tcaaccaata agatttttat
    12721 catgagaaac tcctccttat taaaactatt ataccaaatt tgccttaaaa aaaactcaac
    12781 tctctgcatt ttacatgaga tagctgagtt ttctttttat tttaggctta tttatgcatt
    12841 tccgtattga agaacaactg cttcgactgc agctttttca cggctaatca agtcaacacg
    12901 cgctgcaatt tccttgattc ccataccgat gttacggcta agagcaaggt cagaaagttg
    12961 cggttcaaag aactccttgt attccgccaa gcgttgctga gtcttaaata catgagcagg
    13021 aaggataaca aagctatcaa agctcatatc tcctccaagg gctgccttaa tccaagccca
    13081 gttttcacgc gcccaagacc aagctgtttt ctgagttgct tgatgagcta ggaattggta
    13141 ataccaagca gacaagtcct gtggtttgac cacaaatttg tccttccaag aagtaatcaa
    13201 gttttggata ttatccgcat ctgtactgta tgcaagagct gctgtcaact ggcgtttaaa
    13261 gacagcatct gttgcgtgag tataagtatc aagataaagt gctaacaagt ctttagtctc
    13321 atgatgtttc atctcattaa tcagaacttg tgaacgaata gctgctggga gttctgcaag
    13381 attctccttg tgtgttgcga agatttggct agtgacttga cgagcttctg catcatttga
    13441 gcgaatcatc atcgaaacag ccagctgacg aaccaattca tcctcatctg attctccgtc
    13501 tttagcttca aaaccaagac ggtcatagtt atgacgagcc aatttagcaa ccagtccttt
    13561 gaaggctgtt tcagcatccg ttccttcatc aataaagcgc tcaagggctg aaatcacttg
    13621 agaaacagct gaaaccacca gataagactc ttccttagca agtttatcaa gaactggaag
    13681 caagtctgca taagaaatgt gccctgcctc agccaacaaa cgacgttctt gaacaatttg
    13741 cagtttgctt gtgttatcaa gtgtctctag ctcagcaaga acagcttcta acaagtctcc
    13801 ttgatagtcg gtaatatagt gggcagtatt ttcagtgttg agacgaagag ctccttcatt
    13861 ttcagcaaga agagctgcgt agccagggat ttcgatactt tcagtttcga gtgtatcagg
    13921 caagcctttc cagttgctat tgaggggcac cacccagaga cggttcttgt cttcgttctc
    13981 accgatgaag aattgttttt gtgaaatctt caagacatca ttttcaactt tgacagtaag
    14041 aactgggtaa ccaggctgtt ccaaccaaga atccatgaag gctgcgacat cacgtcctga
    14101 cgcttgacca agggcatccc aaaggtcact accaatggtg ttgctgtatt ggtgtttttc
    14161 aaagtaggca tgcaaacctt tagcaaaatc agcatctcct agccaacggc gaagcatgtg
    14221 catgagacgg cttcctttgg catagacgat agcgccgtca aagagtgtat tgatttcatc
    14281 tggatgttta acttcgacgt ggacagactg aacgccatca gtagcgtcac gttcaagagc
    14341 aagaggtact ccacctgttt ggaaatcttc aaagatattc cagcttggtt cgatggtatc
    14401 cacacagacg tattccatca tattagcgaa actttcattg agccaaaggt catcccacca
    14461 tttcatagtc acgaggttcc caaaccattg gtgagccaat tcatgggcca caacaagggc
    14521 aacttgttga cggctagcaa atgtagagtt ctcatcgaca accaagtaaa cttcacggta
    14581 ggtcacaaga ccccagtttt ccatagcacc agctgagaag tcaggaaggg cgatgtggag
    14641 agattgagga attggatact taactccata gtaatcttcg taaaactcga tagagcgaac
    14701 agcgatatcc agtgagaaat caagatttga aagtggatgt gctttggttg agtagacacc
    14761 taccagggta ccatttttag ttttagcggt caccccttgc aaatcaccag caaaaaaggc
    14821 caacaagtaa gaagacatgc gaggtgttgt ctcaaacttc cagatacctg tttccttacg
    14881 gttttcaaca tcgatttctg gcatgtttga caaggccaat tcaccttctg cttggtcaaa
    14941 gcgaagagag aggtcaaaag ttgctttggc ttcaggctca tccacacatg ggaaagcttc
    15001 gcgcgcaaaa tggctctcga actgagtaga caagacctcc ttcttgactc catcaactgt
    15061 ataataagaa gggtaaatcc ctgtcatgtt gtctgtaatt ttaccagaaa aggcaagaac
    15121 caattcaact tgaccagcct cagccaattc gatatgaagg gcttcattgt catggtcaac
    15181 tgtaaatgga cgagcttgac ctgcaacttc tacagaggtg atttccaagt ctttttggtg
    15241 gagggagatg cggtcactct gtgcttgacc agtgatggtc actttcccag aaaaagtctt
    15301 ggtctcacga ctcaaatcta aaaataaatc ataatgttca ggaacaaatt gcttaataaa
    15361 atgttcaact gcttgcatag ttttctccta ttctaagttt aagagctgct gctcttcttc
    15421 aaacaaactt attatatcat attttgcttg aaaaaaaagg attggacagc gatttccaaa
    15481 actttcttcc ttctaatagt ctacagtggg tagaccttgc gaaattcttc taaaacaacc
    15541 ttgctttcag atgtaaaagt cagccctact tcacccaaac agtctgtgaa aaagtcctca
    15601 tgaacctggc gccaataggc aagtgatttg tctccctcac cttccttaaa ggcatgttgc
    15661 gcagaaactt gattgaagag ttcaacagaa acctttgtaa tttcgacaat gcagacagac
    15721 tgattttgac tatctaaaat gatatcgaag gtccctactt ggggaagtgg ttcgtcttct
    15781 agtacataga ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc
    15841 gctaaaaggt ctggttcaac tccaaaagcc caagcatcga tttcatctcc gatcaaagga
    15901 ttgatttgct tgtatttatt ccacatttct tgcggtatca tgggtactcc tttgtaattt
    15961 tttactttct tcttttatgt gtttaagatg atctggatgg tcaatctcta aatcaaaaat
    16021 ctctggaata gaactgtagt ggataatgca cttgataccc aactgattca ttttttgtat
    16081 gaaagaagta ttcagatagc ctgctacagc aaaatcaatc ttgttctttc ttgctttatc
    16141 ctgcatatct cttagcatat ctaacattat tggactttcc atatcatgcc attgactgtt
    16201 tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa tctttgaaat
    16261 gcccgtttcc agtatactag ataagtcaaa atacgctgac ggtaattcaa tcatcgttcc
    16321 gactttccca gtaaaaccct gctgacgcaa tactgtaata gcttgtttta attggtcgtc
    16381 atcattgaca aaaggaaaga taacagatag attggggttg gtttgataaa cttctgtaac
    16441 gacatgtgct tcagcctgaa attcatccaa acacgccagt aaacgcctgg ttcctctata
    16501 gccaaacaag ggatgccctt cgtcaaaaaa ctctctagtc cccactaaac aattggcttc
    16561 tgtattcgtt aattcagaaa aacgatacca aacttcttca tctgagtaca gggagcagat
    16621 agtctctaga taatctttta caaattgctg acaacttgct aatatgatgt tttgattaag
    16681 ctctctcaac aaatattccc cacgaatcat gccgacgtgg tgaaatagtt gaggataaat
    16741 tttttcaaga attttttcgc cactaagggc aagttgattt ctcatcattc accttccaat
    16801 tcatgtaaga agtcttgtcc agttctggaa atcctaataa ttcagactta accttcaaga
    16861 ctaatggcga tgcattttct tctgtaattt cttgaatatc catccaaata tatccaagtg
    16921 aatcattcgc accatcagac acagcttccg aagtcgtaac ttgaggtgca ctctcattca
    16981 tttcaacatc atacaaggcc atgacatggt gaaccataaa attttttaac tcttctctga
    17041 cgaaaacatc gtagattcga ggattagagt agcttctaac agtaaatctc gtctcttcca
    17101 taacttctct agtcagcgtt tccgtcagtc cttcaccaag ttgctgactg cctccaggta
    17161 gatcataccg atgttgataa gggcctctcg ttttttcaat gcaaagtaac tttccatttt
    17221 caaagcaaac acagtagacc ccaaagtgtt ttttgatttc catccaactc ctcctacttc
    17281 aaagaccagc caccatctat tgtcaagatt tgtccttgca tggcgctcgc ttttccactt
    17341 gctaaaaaaa gactaagctc tgctatttcc tctggctcaa tccagcgctt gattggggtt
    17401 tcactagcca cccagtcagc caaaccacct ggttcaaaat ccgcagcggt catagctgtc
    17461 ttgactgctc ctggagcgat accaaagacc tgaatcccag cttcagcata gtctagagcc
    17521 aactgcttgg tgaagccagc caaggcatgc ttggatgaag tataggcgtg accacctcca
    17581 cctgctaggc tagaagcaat ggaacacata ttgatgatga ttcccttttt attttccagc
    17641 atttgtgtca aataataccg agtcaactct actggaataa tgtagttgat ttcaaaaatc
    17701 tcttgaatgt cctgcgccgt ttgttccaac agtggtttgt aatcatccaa aactccggca
    17761 gtattacaca aaacatccac ctgagggcac cagtcaaaaa taggttccaa gtccaaggtc
    17821 aaatctctct gtaaaaagtg aaaatcaccc tctaagagtg gcttttcacc ttggtcaact
    17881 ccataaactt gatagccctt ctctaaaaag aggcgagctt gagccaatcc gatccctgaa
    17941 ctcactcctg taatgagtac acgtttagtc atgcacttct acccaatccg ttgccaaaac
    18001 atcacaagct gtcgggctcc acatggaaaa accttctcct tctccagaca cgttgattag
    18061 gaaataaggt gtcacttcaa gtgcaagccc attttgctcg atggtatcaa agagttggac
    18121 atagttttcc gcacctcccc aaccagttcg tacatatttt ttcttagcct ttaagccagg
    18181 taaaatttct tcaaatgtca tgtttttctc ctttaatgtc aataattctc cccttcatta
    18241 taacaaaaaa accgctttaa aacggctttt tgactgtgat ttattcaaac ctgctactac
    18301 ttacggcaaa ttattccctg cagcaagata aatttcatac cattcttttc ttgttaagct
    18361 aaagtttgcc gctcggctaa cttctctcaa gtgcttagga tttgttgtac ctacgactgc
    18421 ctgcattttt gctggataac gcaatatcca agaaatggca atagttgaag aggttactcc
    18481 atatttaata gctaaacgat caagtacttg atttaaagct tgaaatttct catttccaac
    18541 aaagttccct ttaaaatacc cgaattgcaa gacagaccat gcttgaatga ccacatcgtg
    18601 taatttgcaa tattcaaaaa tgctgccatc tcgcatagct gcttgactat cttccatatt
    18661 aacatgaaaa gctgattcaa atcctggagt aaaagccgca ctcaattgta gctgattaac
    18721 agctaacggc tgcttgacat cttttttaag caactccatc atcataggat tttgattaga
    18781 aactccaaaa tctcgaactt taccttgttt ataaaggaga tcaaaggctt ctgctacttg
    18841 gtcagattcc atcaaagcat ctggtcgatg aaggagcaag ctatctagat gatcaatctt
    18901 caatctttgc aaaataccgt ctactgattt tataatatag tccttagaaa aatcaaaata
    18961 ggtaaattct tcaatgcgaa tgccacattt ggactgaatc cacatctttt ctcttaaatc
    19021 tggacgattt tttaggacaa gacctaacag ttcttcacaa cgaccacgac cataaatatc
    19081 agccaagtcg aaggcattga ttccaacaga aagtgctgtt tctacaagct cttcaacttc
    19141 ttttacagac ttatctttta ttctcatcat tccgagaaca atttctgata attctttgtc
    19201 atcttgacca agagttatgt atctcatcaa atttttctcc tttaatttct aacattcttc
    19261 ccttcattat aacaaaaaac cgctttgcaa cggctttttg actatacttc actccatttt
    19321 atcttcttaa acccacggaa caagacaaag attccaataa agaggacagc taaaggaata
    19381 acttttgtaa ggaaaacatt tgaaattccc atccactcat aataacggag cagagaaccc
    19441 accacaagat gggcaataat catactgaca aatggacgaa agaccgcttc tttccaattc
    19501 caaataccga taactagcga aatcgtaaag acagacaaac tatcccaggg agccggaata
    19561 taaaaggctc cttcttgtat gaagcttgcc attcctacat atcctaaaac aactagaaga
    19621 actatagtcc caacaacaat gtaagtgcca attttcattt taggagaatc ttggactaaa
    19681 cttcttcgta aaattgtggc cacaagtcca aatccaatca gaaaaataag aagttgccct
    19741 aaaaatgtga gcaaattgac tgttaagaga ggacctttag aaaaatcact tagtagttga
    19801 taataacgta ataccgccag gacaagaatt ggcgtcaaaa gggactcttt gatagaactg
    19861 cgaggtgctc ccttgagaat ctctttcatt atttttttag gattcttacc tagataatcc
    19921 tctgcactca tgccatctcg ttctgcttct gagaaatcta gcatcatcaa atagatctgc
    19981 tctctgagat agtcttcatc atagagaaat ccagcaagat taaaactttc ccacaactcc
    20041 tcaaaatact tttgattctc ctcagaaaac tcatgtagca aagcgcttgt ttcttcgtaa
    20101 tacttcattt tcttcatggt ttaaccccca ttcttaatcc cttctacttt ttgactcaaa
    20161 tcgtcccatt gttgccaaaa gactgagaca cgctcttctc cttctttcat taatgaaaaa
    20221 tacttccgat ctggaccatc tggcgacggg cgcatgtcgc ctcttatcca ttgatttttt
    20281 tctaactttt gcaacaaagg ataaatagtt cctggaacga tagtatcaaa tccagcctct
    20341 cgcaaagtct gaaccaactc ataaccatac cgctcttttt gaccaatcat atccaagaca
    20401 caaccttcaa gaacaccttt taatagctga gtttctttca tcacttctcc cttctaatct
    20461 attttgtaat acctactagt aacttcacct atagtatatc acttctacac tagtttgtaa
    20521 agcataatag ttaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccctaccgt
    20581 atgtagggtt actgacttcg tcagtttcat ctacaacctc aaaactgtgt tttgagctga
    20641 cttcgtcagt ttcatctaca acctcaaaac tgtgttttga gctgacttcg tcagtttcat
    20701 ctacaacctc aaaactgtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga
    20761 ttttcattga gtataaataa aaaaacagaa ctagcctgaa ctagtcctgt ctacttttac
    20821 ccaatcacac ttccatttgg tacagctgga tcaactgtga gaagggttaa tttgccatca
    20881 tgttcagctg agagaatcat accctggctg acatattttt tcatcatttt acgtggtttg
    20941 aggttagcaa cgatttgaac tttcttgccg accaattctt gttcatttgg atagtatttg
    21001 gcaattcctg aaagaatctg acgatcttct ccatcaccag catccaagca gaattgaagc
    21061 aacttatctg aaccttctac tttagacact tctttgactt ctgccacacg gatttcaacc
    21121 ttgtcaaagt cttcaaactt gatttcatcc ttgtttagtt tgagctcaac ttcgtccgga
    21181 ttccattctt tttcgactgc tggtttattg ccttccattt gttccttgat ataggcgatt
    21241 tcttcttcca tatttagacg tggaaagata ggtgttcctt tggcaactac agtcacatct
    21301 gctgggaagt cagccaaact caagttttca agactagaaa cttcttccaa accaagttga
    21361 gtcaaaactg cacgactagt ttccatcata aatggttcaa tcaagtgagc aactacacga
    21421 atgctggctg ccaagtggct catgacactt gccaattggt cacgaagagc ttcatccttg
    21481 gccaagaccc atggtgcggt ctcatcgatg tatttattgg tacgagagat cagagtccag
    21541 actgcttcaa gcgcacgtgg atagtcaact gcttccatgt gtgtatggaa gtctgcgatt
    21601 gattgttctg caacctcagc aagaacatga tcaaattcag tcacaccttc tacataggca
    21661 gggatttgtc catcaaagta cttattaatc atggaaaccg tacggttaag gaggttccca
    21721 aggtcattag ccaattcata gttgatacgg ccaacatagt cttcaggagt aaaggttccg
    21781 tctgaaccaa ctggaaggtt acgcatgagg tagtaacgaa gtggatctag tccataacgc
    21841 tctaccaaca tttcagggta aacgacattc ccttttgact tagacatttt tccgtctttc
    21901 atgacaaacc aaccatgggc aatcaaacga tcaggtaatt taacatccaa catcataaga
    21961 aggattggcc agtagataga gtggaagcga aggatatctt ttcctaccat atggaagact
    22021 gttccattcc agaacttgtc aaagttacca tgttcgtctt gagcgtagcc aagagctgtc
    22081 gcatagttaa gaagggcatc aatccaaacg tagacaacgt gttttggatt tgatgggaca
    22141 ggcactcccc atgtaaaggt tgtacgagat accgccaaat cttccaaacc tggctcgatg
    22201 aagttgcgta gcatttcatt aaggcgacca tctggcgtga taaattcagg atgagctttg
    22261 aaaaattcga ccaaacggtc ttggtatttg ctaaggcgaa gaaagtatga ttcttcagaa
    22321 acccattcaa cctcatgacc tgatggagca ataccaccag tcacatttcc agcttcatca
    22381 cggaaaactt ctgccagctg gctttctgta aagaattctt cgtctgatac tgaataccaa
    22441 ccagagtatt cacccaagta aatatcatct tgagcaagta agcgttcaaa gacctgtgcg
    22501 acaacttttt catggtagtc atcagttgta cggataaatt tatcgtatga gatatctagt
    22561 aattgccaga gttctttaac tccaaccgcc attccatcaa cataggcttg aggtgtaata
    22621 ccagcttctt ccgctttctg ctggattttc tgaccatgtt catcaagacc tgtcagataa
    22681 aatacatcgt agcccatcag gcgtttgtaa cgtgctagga catcacatgc gatagttgtg
    22741 taggcagaac cgatatgaag tttcccagat ggatagtaaa tcggcgttgt aatataaaaa
    22801 tttttttcag acataatttt tcctttccag gcaaatgaaa cctgtttttc taacacttca
    22861 ttatatcaca tttttaatga atttcgatag ggaaatccat acaaaaacaa gatagacgag
    22921 tgtccatctt gttgatctca ttcataacga agggcttcaa ttggatcaag tttcgatgcc
    22981 ttgttggctg gcaagactcc aaaaatcata ccaacactag ccgaaactgc aagactaaat
    23041 agggcaactg ggattgatac tccaacttct ataccttcta ttaaaccttg cagtaacaaa
    23101 cctgctaagg cagttaaacc acttgcaatt gtcaagccaa ttaagccacc taacaaggtc
    23161 aaaatcatgg attcaatcaa aaactgaatt aaaatattgg cacgtgttgc acccaaagcc
    23221 ttacgaagac caatctcacg agtgcgctct gtcaccgaaa ccagcatgat gttcatgaca
    23281 ccagttcctc caacaaagag agaaatccct gcgatggaac taataatcgt cgtcataaaa
    23341 ctaaacgatt gttgaatttc tgcaaataca acggactcat ctgccacctg gtattctccc
    23401 tgttgtaagc ctgcaagctc tgtcattttt cgtgccagtt ctggacccag agttggggtt
    23461 aaactggtat cattcactcg aaagacaata ttagctattt catctacatt aaaattcgca
    23521 gcaagggaga tattggtagt aataggcaag ccaccaaacc catatatttt tgatctttta
    23581 gcctccggac tagtataaac cccaatgacc cggtaactaa atccattgac ttctacaacc
    23641 ttgttaatag cctcttgagg agattcaaat aaactaatgg acaattcctc atctagcaaa
    23701 atgacacttg caaactcttt gaaatcttgc tctctcagac tacgacctgc aataatttca
    23761 ttcttaacag cgtccatgta agttctgttt ccacctgtca aattagcatt ctcaaccttt
    23821 ttatcttgat aggtcaagat ggcattcgtt gaattggtta catagtaact atccactccc
    23881 ttcagtttag ctgcctcttg gacccaggat tcttgcggtt ttggcggttc aacaggaact
    23941 tcctcttcct ttccagaaac cgtaaaagct gattgtttct gagtaaaaga cccatcttta
    24001 ctttttttag gagagaaaaa gacgctaata tttttctgag atttagtcat atctttattg
    24061 acttgacgag atagggaatc acccaaagcc ataatcacaa caactgatga aacaccgata
    24121 ataatcccaa tcatagtaag caaagaacgc atcttgtgag ccatgataga tgaaaaggca
    24181 aatttcagat tctgcatctt agttttcctc ctttcctaac tgagcactgt cagacgaaat
    24241 gaccccatcc cgaatgacaa tctgacgttt ggcataggca gcaatctcag gctcatgcgt
    24301 taccatgata atggtttttc cttctttatt caaatcaacc aataattgca taatttggtt
    24361 acctgttttg gtatccaagg ctcctgtcgg ttcatccgct aggataatag aaggattgtt
    24421 taccaaggca cgcgcaatgg ctacacgttg cttttgacca ccagataatt ctgaaggtaa
    24481 atggtgacta cgttctgtca attcaacctt gtctaaatat tcctcagcca acttgcgacg
    24541 ttttgaagac gaaactcctg cgtaaatcaa gggcaattct acattttgca gagcattgag
    24601 cttcgataga agaaagaact gctgaaagac aaaaccgatt tgttggttac ggaccttagc
    24661 tagttgtttt tcaccaagcc cagccacttc ttgaccttca agataatatt ctccactggt
    24721 tggtgtatcc aacatgccaa tcgtattcat cagagtggac ttaccagacc cagatggtcc
    24781 catgatggct acaaattcac cctcattcac ttctagattg atatttttga gaacctgcag
    24841 ttcttggtca ccattacggt aacttctgaa gatatttttt agactaatta gttgcttcat
    24901 cagccttcac ctcttttcct tcttccaagg aagatgttgg attactgatg accttagcac
    24961 cgttcgttaa accagaagtg atttcttgat tttctgcgtc agcatttccc aatgaaacct
    25021 caactttttt agccttttgt tgttcatcca caatccagac ataattttta ctatcatcca
    25081 ttactagact gctaacagga acaagaatag ccttagtttt gcttttaacc tcaatgttga
    25141 cagaaaaacc ttgtttcaaa tcaccaacct cgcctgtcac atcaatagta taagggtatt
    25201 tagaacctgt attattcccg gctgctggac tagctgcttc accattgttt ttaggatagt
    25261 cagaaatata gcttaatttc ccagtccatt ttttatcagg atacacttta gaagtaaagc
    25321 ttacttcttg acctacagaa aggttggcta gattgtactc agacaattct cccttgactt
    25381 gtaaattttc attgctgaca atatgaacca taacttgact cgcccctgtt ggagatttag
    25441 aaacattgct attgacttcg actacagttc cctctagggt actgagaaca gttgttgcat
    25501 ccaattgact ttgagccttg cttaattgcg ctgcagcatc tgcacgcgca tcacgggcat
    25561 cacccaattg agcatcaata gaagcaacag aatttccagc cactggagtt gggctttgca
    25621 ccgttgcatc ttctcctcct actggcgctg gtaactgtgg agcctgagct gaagcggctt
    25681 catttcgtgc ttgattgagt tcattgatat gacgatctgc cttagctact gctcgactag
    25741 ctgaatcata ggccgcctgc gcttctgaac tactgtactt gactaaagcc tgcccttcgc
    25801 tgaccttatc gcccacagaa acaaggattt catctaaatc acccttacta gcatcaaaat
    25861 aaacatattg ttcatttttt gctgttactg tccctgacaa taaaacagag gatgccacgc
    25921 ttccttcatt ggcaacaaca agatgagtag gctcatcttt tagagcagtc tgagaaggtt
    25981 gtctaaagag taaaatcccc ccggcaccca atacaactac actcgcagca ccgattgctg
    26041 catacagttg ccacttttta gctttaccat tctttttctt cataatgaaa ctccttttct
    26101 tttttacaat actttgctat tataccaaat ttccctccag caaacaatgc agttcagatg
    26161 gaaataatgg cagttcagga ttaaacaatc gttcggaatt ttgcttttct attgtactag
    26221 atatataata cactatcttg acttatttgg caagcttttt tgcaattttt tgtgcgtagc
    26281 agatttttgc aatcaaatca aaaaaagaat aaaatataac tatcaaaaaa gacactctac
    26341 tatttaaaag attacaaagg agttttcaat gagagaatat gatatcattg ctatcggtgg
    26401 aggtagcgga ggaatcgcta ccatgaaccg tgctggtgaa catggagcca aagcagccgt
    26461 tattgaggaa aagaaattag gtggaacctg tgtcaacgtc ggttgtgttc ctaaaaaaat
    26521 catgtggtac ggggcgcaaa tcgctgagac tttccatcaa tttggagaag actacggctt
    26581 taagactact gatcttaact ttaactttgc aaccctacgt cgcaatcgtg aagcctacat
    26641 tgatcgcgct cgttcttctt atgatggtag ttttaaacgc aacggtgtag acttgattga
    26701 aggtcatgct gaatttgtag attctcatac tgtaagcgta aatggtgaac tgattcgtgc
    26761 taaacatatc gtgattgcta caggtgccca tccaagtatt cctaatattc ctggtgctga
    26821 gctaggtggc tcttctgatg atgtatttgc ctgggaagaa cttccagagt cagttgccat
    26881 tctaggcgct ggttatatcg ccgttgaatt agctggcgta ctccacactt ttggtgtcaa
    26941 gacagatctc tttgttcgcc gcgatcgtcc tttacgtggt tttgattcct acatcgttga
    27001 aggtttggtc aaggaaatgg aaagaacaaa cttaccactt cacactcaca aagtccctgt
    27061 caagttagaa aaaactactg acggcattac cattcatttc gaagatggta ctagtcacac
    27121 agctagccaa gttatctggg ctacaggccg ccgtccaaac gttaagggct tgcaacttga
    27181 aaaagctgga gtgactctga acgaacgtgg ctttatccaa gtggatgaat accaaaatac
    27241 tgttgttgag ggaatctatg ctctaggtga tgtaacgggc gagaaagaac tgactccagt
    27301 tgcaatcaag gccggacgta ccctatctga acgtctcttt aacggaaaaa ctactgcaaa
    27361 aatggattac tcaactattc caactgttgt cttttcacac cctgctatcg gaactgttgg
    27421 tttgacagaa gagcaagcta ttaaagaata cggtcaagac caaatcaagg tttacaaatc
    27481 aagctttgca tctatgtact ctgcttgcac tcgcaaccgt caagaatccc gtttcaaact
    27541 cataacagct ggttcagaag aaaaagttgt cggacttcat ggaattggct acggcgttga
    27601 tgaaatgatt cagggatttg ccgttgctat caaaatggga gcaaccaagg ctgactttga
    27661 cgcaactgta gcgattcacc caacttcatc tgaagaattt gtaaccatgc gttaatcgaa
    27721 acaaaagaag ctgatataaa tatgtctgct tcttttttaa tgattttcga atcaacaaaa
    27781 aattatccaa cttgactagt cacgaaaatc ggctgttaca gtttttgtta ccttgttttt
    27841 aaaaaatggt tgacatcgac tcctatatga gtataatagt tactatacat tagaaaagag
    27901 gttaactatt ttgaaaaaag ctcacgttta tgctatccct gctattgggg ctgctctcat
    27961 tgctgttttg gcacaaatca gtcttccaat tggacctgtt cccttcactc tgcaaaactt
    28021 tgcaatcggc ttgattgcta ctgtctttag accgagagag gctgtacttt ctgctggact
    28081 ctatcttctt ctaggtgcta tcggtcttcc tgtctttgca ggaggtggag ctggttttca
    28141 ggctttagtt ggccctactg caggctatct ttggttttat ctcgtttact ctggacttac
    28201 ttcctctcta accaacagca agagtggtgt tgttaagatt tttcttgcaa acctcttggg
    28261 tgatgccctt gtctttgtcg gcgggattct cagcttgcat ttcctagctg gaatggcatt
    28321 tgaaaaagct cttgttgtgg gggttcttcc ctttatcatt ccagaccttg gcaaacttct
    28381 ggctattagt tttattagcc gtcccctact tcaacgcctt aaaaatcaga cttactttac
    28441 taactaaaaa aggataccga gttatcatga ctcaatatcc ttttttttat tttgaaaact
    28501 tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc tcaaaacact
    28561 gttttgaggt tgtagatgaa actgacgaag tcagtaacca tacatacggc aaggcaaagc
    28621 tgatgcggtt tgaagagatt ttcgaagagt attagttgcc tttaaaggca tccaccatcg
    28681 tttgaaattc ttcatttgag agagtaatcc ctttgcccat tttagtatgg tctggactcc
    28741 aagcacgaat atcaaacttt gcaggggcac cattaaagct cacacggtta atttccttgg
    28801 tccaaccttt ttcgttttca gaaagagtca acaagtgctc ttcgatttca aatgtaaatt
    28861 ctgccatttt cttctccttt tttagtttca ttagtttatt cgtaaaatct tgtagatttt
    28921 aggaaaattt tatataatat tgatataaaa gaagggaggc caatatgaga cataaattcc
    28981 agcaagttct agataaaata catgattttt taaatggaca tgaccaacct gaccagactg
    29041 aaaccaactc ccttacagcc actattgaag aggctatcca gaaacaaacc gctgttcacc
    29101 ttatcttgtc tgagacaagc tttacaggtg atatcatcaa atatgatcag caaggccagc
    29161 aaattatcgt gaaaaatttt tccaaaaatg tgagccggat tatccgtata agcgatattc
    29221 aacgcctgcg atttgtcccc tcaactgtcc aaacagccca aaaaaataga tttaagaaag
    29281 agtgagatgt agttgcttca tcccactctt tttcttagcg aatttgttca aaatgtaaat
    29341 gaactgcgat atgatctcca taaccacttc tttccaagtc acgttgtaaa cgataggaaa
    29401 tatagtgttc tgcaatggta atgtaacctg cgcccaataa acgatgttca accatagatt
    29461 gaatcatact gatagtcgca cgttccacct tggcttcttg taaatccaaa actaccttct
    29521 tagtgacttg agcaagattt tgacgcaaat catctgtcaa aacataaaca gtttgggctg
    29581 ccttcaagat ggcttggtaa atcttatctg gattaaattc agcaatttcg ccattacgtt
    29641 tgattacttg cataggtttc tcctttattc tttgttttct ttgatttctg ccagcatttt
    29701 ttcttcttct actgtcagtt gataatgttc aagtaaatcc ggtctgcgct cgtaggtttt
    29761 ctttaaactc tcgtacaatc gccactgacg aatcttttca tgatggccac tcatcaatac
    29821 atctggcacg accatgcctc gataatcata gggacgtgtg tactgaggat attctaaaag
    29881 acctgaagaa aaactatcat cttggtggct agactccttg ccaatcactt ctggaatcag
    29941 gcgaactgta gcatcaatca tggtcatagc tgccaattct ccaccagtga ggacatagtc
    30001 gcccagggaa atctcatctg ttaccaaggt cttaatgcgc tcatcataac cctcatagtg
    30061 cccacagata aagattagct cttcctcttg agccaaatct tcagcataag cctgatcaaa
    30121 ctgctttcca gcaggatcga ggagaataac gcgcggattt ttcttttcaa tagcatcaaa
    30181 ggaatcgaaa ataggttgtg ctctgagcaa catgccctga ccgcctccgt agggctcatc
    30241 atctacatga cgggcctttt cagcattttc tcgaaaatta tgatactgga tatccaagag
    30301 ccctttttct cgagcctttc caacgattga gtgctccagt ggagaaaaca tctctggaaa
    30361 gagggttaaa atatcaatct tcatcgtcta acccttctaa gatttccaca tcgacccgtt
    30421 tatttggaat atcaacattg agaaccactg gtgggatata aggtaaaagc aaatcacgtt
    30481 tgccttttcg tttgaccacc cagacatcat tagcacctgg ttgcaggatt tccttgatgg
    30541 ttccaaccaa gctatcaccc tcatagactt ccaaaccgat aatctcgtga tagtaaaatt
    30601 caccatcgtc taggtcattc aaatcttcct cagcgacctt gagactgtat cccttgtact
    30661 tttcgatagt attgatatgg tacatatctt tgaatttaat aatgtcaaag ttcttctgtt
    30721 tacggtggct agcgatggtc actgtttgga caaactgatc tttttcatca aacaaagcca
    30781 gctcagctcc ttttttaaac cgttcttctg caaaatccgt cacagacaag actcgcatct
    30841 caccctgtaa tccctgcgta ttaacgattt tcccaacatt aaagtagttc atcttgtctc
    30901 ctgtaatctc cttttttcca tcttattctg acaattctcg aataatagcc gcaatttttt
    30961 ccgattctga ccattgtaaa taatggtgat tccctcctaa aatgagttta gtattggaag
    31021 tccaatattc tgattctctg tactcttttt ctctataagt ctgacaaaaa ataaatatag
    31081 ggacatgaga ttctatcgac aaattctcaa aatcttcctc agtaatctct ccagatatct
    31141 gaaattctgg atcttgattt tccaactcta agcctttttc ttgcattaat tcccagattt
    31201 ttttattcgt ttcaggacta aatgttgctt gagttaagtt cttaaaataa agttcaggac
    31261 cacactcgtc aatcagcctc atctgctctt ccatttctgg ataaggattt tctgaaaaat
    31321 cagcaaacat gactttttta gttgtcggtt caattgctac taaagtctga cacttaattg
    31381 gtttctcgag taatttgcaa gctaaaattc cactccaact atgtacacaa agtatatatt
    31441 cagaaatccc taattcttca agtgcttcat aaaccacatc tgcaagatta tctagatttt
    31501 ttccagcttg gtcataaatc ggactcctac ctgtgttcgg aaaatcaatt gtcaaataac
    31561 caattgtagg aggaggtttt tcaagtataa gtgaaaaatt ttcataactt ggtagcaaac
    31621 ctgctccatt tagacaaact agcactttct tttgcttttg ataagcaaca gagagactac
    31681 caatttctgt agatacttca aacctcttca taaagaaatc cactgattct atataatgaa
    31741 ttattaaaaa tccttatcct ttattttatc acgttccaag gattttctca agttggagga
    31801 aggggacaac atctctactt tcccttcaag aatccttcca aatcatgttt atgttggtaa
    31861 ttaacggctg cggttttgtc tttctcaaag atggttctag ttaggtcaat atgcttgata
    31921 gcagcaatag cgacggtgta gagaatgata tcagccagtt ctctggcaag ttcctcgttc
    31981 gaatcctatc ccttcttttc gaccagagcg cctattcaaa acctcggcta cttctccgac
    32041 ttcctccact aacttcataa agagaccttc atcagtccga gactgctgtt aatgttcgag
    32101 taagtagtct tggaattgcc taaacgttca atcttttata gtatattgaa actagaatag
    32161 tacaccttta cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc
    32221 tgttattatt tcattttact atatcttcta ttccacacaa aaaagcgaga catccgtccc
    32281 gcccttctta tttttcgtca ataacgattc ttactttttt gtattcagtt gggacagagt
    32341 agacaatcgt tcttatcgca gaaatagtgc gacccttacg accgattaca cgacccacat
    32401 cgctttgatc aagattcaaa tgatattcca aaaattctgg tgtatcctca atcttgatag
    32461 ttaaggcatc tggttgtgaa attaagggtt tcacaatcgc aataatgaga ttttcaatcg
    32521 tatccatctg tcaacctact ttaaacttat tttgaaaatt tagaatcgtg gaattttttc
    32581 aatacgcctt cttttgaaag gatgttacgt actgtgtctg aaggttgagc tccattagcc
    32641 aaccatgtaa gaacgcggtc ttctttcaaa gttacttggt tttcagcaac aagtgggttg
    32701 taagttccaa ctgtttcgat gaaacgtccg tcacgtggtg aacgtgaatc tgctacgttg
    32761 atacggtaga aaggtttttt cttagaaccc atacgagtca aacggatttt aactgccatt
    32821 tttaaagtct catttcttta attttttatt tcggtgaaat agctgagcta tttagcacat
    32881 gttctattat agcagatttc tggcaggtgt caagaaaaaa acttgacaga ctataaattt
    32941 cttaaagcat ttaaaaattt gttagaatag gaaataaatg tttgaaagat gctatccgtg
    33001 aatactattt tagaaaaatt ttataaagaa caccaagtca aacccttcat atcgcctgaa
    33061 cgagatttgg atacttggct tctaagtccc aagcccgttc ccaagcgaaa tatggactta
    33121 ttagtagatg attcactagc aggagatatc attttactat ggagaatcca gtttggtact
    33181 tttaccactg aaacatgatt ttaaaaactc ccattcgaat atgattcaaa attcgcttag
    33241 aatcaatgtt ttcccacttt ttcaaaaaat aaattttcat ctaatttaaa taactttcaa
    33301 ttaagtgtga attttgctta aaatcattaa aaaacacccc atggtgtgaa ccatgaagtg
    33361 ttgtaaatgc tgtgttgtag ctagttctta gcgtttagag aactggctag ctttacgagc
    33421 tttcttaaga tctggtttcc aaaatacttt gagtacactt atggtattga tgcccctaaa
    33481 catctaaaaa ctctggtaga aaaagggtat gctcttgtcg aaacttcttt tgactcactt
    33541 gaccatctaa ataataccat gaaaaagaat atcctgaaga agaagggagt tactggactt
    33601 tctaaaatga aatcttgcga cctggatcaa gcccttcatg agtatttttc agaagaagaa
    33661 ttagctggtc actttcatgt ccttctatgg acttttttac aatggcattg ctatcacacc
    33721 caatacctat ctaagcgcct ggttcgtaaa ctttattgca gctcttcctc taaatttcct
    33781 aattgttgaa ccaattgccc gttttatact aagttctttt cagaaaccat ttactgggga
    33841 agaagttgaa gaagttgaag atttttaaga tgatgatgaa atcccaacta ttatctaagc
    33901 cagttctgta aactactaat atttgaaatc cacttccttt tagggtacaa tggttataaa
    33961 tgaatttttg agaggaacag aatgaaaaaa ctagcaaccc ttcttttact gtctactgta
    34021 gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg gtgatgatta tgttgattcc
    34081 agtcttgctg ctgaagaaag ttccaaagta gctgcccaat ctgccaagga gttaaacgat
    34141 gctttaacaa acgaaaacgc caatttccca caactatcta aggaagttgc tgaagatgaa
    34201 gccgaagtga ttctccacac aagccaaggt gatattcgca ttaaactctt ccctaaactc
    34261 gctcctctag cggttgaaaa tttcctcact cacgccaaag aaggctacta taacggtatt
    34321 accttccacc gtgtcatcga tggctttatg gtccaaactg gagatccaaa aggggacggt
    34381 acaggtggtc agtccatctg gcatgacaag gataagacta aagacaaagg aactggtttc
    34441 aagaacgaga ttactcctta tttgtataac atccgcggtg ctcttgctat ggctaatact
    34501 ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc aaaactctac agatacctct
    34561 tctaaactcc ctacaagcaa gtatccacag aaaattatcg aagcctacaa agaaggtgga
    34621 aaccctagtc tagatggcaa acatccagtc tttggtcaag tgattggcgg tatggatgtt
    34681 gtggataaga ttgctaaagc cgaaaaagat gaaaaagaca agccaactac tgctatcaca
    34741 atcgacagca tcgaagtggt gaaagactac gattttaaat cttaaaaacc aaaaaaatac
    34801 agtatccaca ttcggtactg tatttctttt actctcattc ttaagttaaa ttattaaaat
    34861 cccatatttg gtctatccaa ccttcataaa agtctggatc gtggcagacc ataaggatag
    34921 atcccctgta ttctttgaga gcgcgtttga gctcatcctt tgcatccaca tccaaatggt
    34981 tggtcggctc gtccagcact aaaacgttgt tttcacgatt catcaagaga cagaaacgaa
    35041 ccttggcttg ctctccccct gataatactt gaatctggct ttcaatatgt ttggttgtca
    35101 aaccacaacg ggcaagggct gcacggactt ctgcttgatt aagggcagga aaggcattcc
    35161 agacagcttc aagaggagtt tggcgattac cgccttctac ttcctgctca aaataaccaa
    35221 gttctaaata atctccacgc tccacttccc cagcgattgg cgagataatg cccaagagac
    35281 tcttcaagag agttgttttt ccaataccat tagcaccaat aatcgcaacc ttttgattgc
    35341 gttcgaaggt aagatttaaa ggcttagtaa gaggacggtc gtaaccaatt tgcaagttct
    35401 tggcttggaa gataaagcgc cctggtgtac gagctggttt gaaatcaaag gatggttttg
    35461 gtttctcact ttggagttcg ataatatcca tcttatccaa tttcttttga cgagacatag
    35521 ccatattacg agttgcaaca cgggctttat tacgagccac aaagtccttg aggtctgcaa
    35581 tctctttctg ctggcgttcg taggctgcct ctagctgaga tttcttcata gcataaactt
    35641 cttggaactg gtagtagtca ccagagtaac gcgtcagctg ttgattttcc acatgataga
    35701 caatattaat aacgtcattg aggaatggaa tatcgtgcga aatgagaaca aaggcattct
    35761 catagttttg gagatagcgc ttgagccaat caatatgctc agcatccaag tagttggtcg
    35821 gctcgtccaa cagcaaaata tcaggctttt caaggagaag ttttgccaaa agcaccttgg
    35881 ttctttgccc acctgacaaa gaagttacat ccgtatccat gccaaagtcc ataataccaa
    35941 gagcacgcgc tacttcgtca atcttagcat ccaaggtata gaaatcacga ctctccagac
    36001 ggtcttgaag ttctcctact tcttccatga gagcatcaac atccgcgccg tcttcagcca
    36061 ttttcatata gaggtcattg atacgagctt cagctttgaa aagctcatca aaagccgtac
    36121 ggagaacatc acgcaccgac tgtctttcag caaggacaga gtgctgatcc aagtaaccag
    36181 ccgtcacata tttggaccac tcaacctttc cttcatctgg cagcatttta ccagtcacga
    36241 tactcataaa ggttgatttt ccttcaccat tggcaccgac caggccgata tgttctccct
    36301 tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc accaaaaccg tgactcagat
    36361 ttttaacttc taaaatactc attttaattc cttaccttgt ttttatgtaa tcgtttataa
    36421 aggagccaag ccagatagcc acccaaagtg ttggtccaca aatcatcaat ctcaaagacg
    36481 cgattgaaat caaagaaaaa gtccaagatt aattgcgtac actcgattcc aagactcaca
    36541 agaaaactaa aaagaaggac cttttttgtt ttccgcaaat ttggaaatag ataaaggagt
    36601 tggaaaatca gaggaaaaaa caagaagaca ttgaggatat tttgtaaaaa aatccaacat
    36661 aattgtccaa tgtcactcac ttcgcccagt ttccagagag aattgaaagg agtcaaaaga
    36721 aaaaccaggc gtccaagatg ctgaatacct ggagttccca ctcccacggt agattgttct
    36781 tgaggagtaa agcaaaaaca gacaatgcaa atgctataga aaatgactcc ccagaccaaa
    36841 atatgattat aagtcttctt caccattaag gatttaccgc tgcgactgcc ttctggcggt
    36901 cacgtttcat tgtgttagag cgcaattgtc cacaagctgc gtcaatatct gtaccatgct
    36961 cttgacgaac cacacagttg accccttttt tcttaagcgt atcatagaaa gccaacacgc
    37021 gctctttggg actacggcta tattggtcat gctcactaac tgggttataa ggaatcaagt
    37081 ttacataaga caatttcttg atgttcttga gcaattcagt caattccaag gcttgttcta
    37141 caccgtcgtt gacttcatta agcatgatat attcaaaggt tacacgacgg tttgttgtct
    37201 caatgtagta ttcaatagca gcaaagagtt tttcaatcgg aaaggcacgg ttaatcttca
    37261 tgatacttga acgaagttca ttgttaggtg cgtgaagaga cacggcaaga ttgacctgaa
    37321 ccccttcatc agcaaagtca cgaattttat gagccaaacc tgaggttgaa accgtgatgt
    37381 gacgagcacc gatagccatt cctttatcat cattgatagt acgaaagaaa ttcaagacat
    37441 tgttgtaatt atcaaagggc tcaccgattc ccatgacaac gatatggctg acgcgttcat
    37501 cctgaccacg ctcatcaaag tatttctgaa ccagcatgat ttgcgctacg atttcaccgt
    37561 tattgaggtc acgttgcttc ttaatcaaac cagaggaaca gaaggtacaa ccgatattac
    37621 agccgacctg agtggtcaca cagacagata aaccatagtg ttgacacatg agtacagtct
    37681 caattaacat accgtcaggc aattcaaaga gatatttgac tgtaccatca gcagactctt
    37741 gcacaatacg ttgtttcaag ggattgacca caaactggtc attgagctta gcaatcaaat
    37801 ccttggaaag gttggtcatt tcttcaaatg actgcacacg tttacggtag agccattccc
    37861 agatttgatc tgcacggaat ttcttttctc cctgctccaa tacccattcc tgcatggttt
    37921 gatgtgccaa actatgaatt gagggtttca tttcttctcc ttattctcta ctcacttctg
    37981 acgaatgaca aaatgacgtt gttccttgtc ctctttctga gaatgctggt ctttctgacg
    38041 acgtctattt ttcttatctg cattcgactt tcgtttagtt tgagtcggtt tctttccttt
    38101 tctagaaggt gtttcttctt ccgtcttacg cattttcttg tcaaatgatg ctcgcttagg
    38161 ggcttcattt tctaagacaa aataggcaca accataacta caatactcta aaaggtagtc
    38221 ttgtaaacga ctgatttttt caagtttttc ttctgttcgg tcatccttgt aaaaacctcg
    38281 taggcgaagc tgttcgttgc tccagtcccc cacgatataa tcaaacttgg ttaatacttc
    38341 tgaaaaacgc tgattaaaag tcgtcacatc aaaggcatcc ttgatatttt caaccaagga
    38401 aaaagctatc ccttccgttt cgaccttgtc cccgtgtaaa tggaactccg gaccaggaaa
    38461 cttgttatag ttgtataatt caggtgcaat ttcttttcgc atagatatcc tttttccacg
    38521 attacttaat actttattct accataattt ctagcagtta gcacgtttct cataaaaatg
    38581 aaaaaagtct gacgattttg tcagaccaga atcttataac ctaaaaaaga gaagaacaat
    38641 tcttccctcc aactatcatt atttagcagc tgcgtacaat tcatctactt tattccagtt
    38701 gattactgaa aagaaagctt tgatgtagtc aggacgcacg ttgcggtatt tcacgtagta
    38761 agcatgttcc caaacgtcca agcccaagat tggtttttta ccttctgaga ttggtgtgtc
    38821 ttggtttgct gttgaagtca cttcaagttt cccttctttg ttgacaacca accatgccca
    38881 acctgaacca aaacgagttg ttgctgctgc agtgaaggct gcttggaatt cttcaaatga
    38941 accaaatgtt gcatcgattg ctgctgccag ttctgctgaa ggagctgttt tctcgggagt
    39001 catcaattcc cagaaaagag cgtgattcaa gtgtccgcca ccattgttga taagtgcttg
    39061 acggatatca gctgggatag attctacatc agcaagcaag gcttcaaggt cttcaccgat
    39121 ttcagggtgt ttttctaaag ctgcattggc attgttgaca taagtttgat ggtgtttgtc
    39181 atggtgcaaa tgcattgttt ccgcatcgat gtatggttcc aaagcgtcgt atgcatatgg
    39241 aagttctggt aagataatag ccatctgtaa tacctctttt tctttctata tgaaaatgat
    39301 aacgcaaaca ttcacttttt tcaagttttt tgcttataga taaggaaatc actgacatac
    39361 tttctaataa aataagcaaa tcagcaagaa acccacgaca agataatcct gacgcgggtt
    39421 gtagtttcaa caaatgtcaa ttgacctgac tagcaatctg taagagtgcc ttttcaaaaa
    39481 ggaaaccttt ttcataaaga cctgtcttaa tctgatagtc tgtctcaatc aaataggaaa
    39541 tagcttgctt caaaaagctc aaagaaagtc ctctcgaatc tcttaatgca aacttgattt
    39601 gataaggatt tgggttacgt cccagataac tacctaaact acttgcaatc tgcgattctg
    39661 tttggccaga ctccgccaaa atcttcacct gagtaaaagt ccgaaattgt cccagcatga
    39721 ctgcaatcag tttgatttca tcttcccctt gcaaggtcaa gtctctcacc aaatcgcgcg
    39781 cctgatccat ctttttagtc agaataaact gagttaaatc aaaaatattg tcctgcaagg
    39841 tcttgggaat tgcgttaaca atatcctctt cctcaataac agaattcgcc ttataggact
    39901 gtaaaaagag aagatttttc tggatttcgc taaattgaaa ccccgacttg atgaggagat
    39961 tttcaaaaga atgattggta aactgcagac cttgtttctg actccacttt tggaaatact
    40021 ggcgcaattc ttgttctttt acttctactg catcgaagac cttggcatca cgcttaagta
    40081 atttgactaa ccgtcttttg ctatccagct ttccttctgc aaagattatc aacttggttg
    40141 ttggagaagg attgtcaagg tattcctcaa atgacttaag ctcatcatct gtcaaaaagc
    40201 gtttcttagc agtcgtgata tccataaaat aatctaatat cacgattttc tcatccgcaa
    40261 agaaaggaag gctgaccaac tccagttcca catccttgta aactacttct ttcatatcaa
    40321 agtaggcaaa gttgaggtca gcagaatcat acccaatctg tttcaacatt tgactcttca
    40381 tcacttcaaa ctgaccctga tctgtccctg taaataggct caggctcggt aaatttgata
    40441 aagtcaactt ctgactttct tcaatggcta gcatcgtctc tcctttcttc agatttttcg
    40501 atttaattta gtcaatatag cgcaatttcc cacggaaatc ttctaagctc tcgtagcctt
    40561 tttccaccat gattgctttc agttcattgg taatgcggtc aaaagcactg acgccttctt
    40621 tgtgaagggt cgttcccacc tgcaccatac ttgctccaca gaggatgtgt tcaaaggcat
    40681 ctcgaccagt cagaacgcca cctgttccga taatttggat ttgaggattt aaacgttgat
    40741 aaaaggcgtg aacattggct agagcagtcg gtttgatgta ttctccacca attccaccaa
    40801 aaccattctt aggccgaata acgacagatt cgtcttctat atagaggccg tttccgatag
    40861 agttaacgca gttgacaaac ttgagcggat atttgttgaa aatagctgcc gcttgatcaa
    40921 agtgaacaat atcaaaataa ggtggcaatt taattccaag aggtttggtg aagtaagcaa
    40981 acacttctgc caaaatccgg tctgttgtct caaaatcata ggcaatctga ggtttacctg
    41041 gaacatttgg acaggaaaga tttagctcag tcagaccacg aaaatcactc tcttggactt
    41101 ttttcaaaat agtatgggtt tcctctggag acataccgac cagagataag aagaaagttc
    41161 ggttcgactc tttttcctgc aaatctaaaa gataatccaa ataatagtct aagccattat
    41221 ttggcaagcc catagagttg atggaaccaa gtggaacatc ttggtagcgt ggctcaggat
    41281 tcccctgacg gaagtccaag gtcgctgtct tagtaacaaa ggttcctgcc gctgagtttt
    41341 tgacctcttc taactcctct atcgtcatac aagccacacc tgctgcattc atcaagcaat
    41401 tgtcaaactc aaaaccagca atttgtgttt tcgttgatac catgattcta atcctccaga
    41461 tttcttttat tgctaatatt ataccataat tttaattcta ggtttactag attctgtggt
    41521 tctatctatt tattcggaaa agaaagtcta gtacagaagt catgctatgg aaacagctag
    41581 tgtattggaa gtttgaacaa ggcttgggta acagactttt gaatgaagtc caagcaacaa
    41641 ggagaaatct caaccatgag tccattccat gactctgttg ctctagaaaa ccttgcaata
    41701 gtcaagtgat aacgaataaa actttggctt gaaatatccc catgattatc tattacgagg
    41761 agaaatctca acctttatca tttttaaaga aatattgtaa aatgaaacaa gaacaggaga
    41821 aatcgatcag gacagtcaaa tcgatttcta acaatgtttt agaagttgag gtgtactatt
    41881 ctagtttcaa tctactatac atgtaaatct ctactttcgc aaaatggatt ttcagaacag
    41941 tatcccagta tagttaaaaa ctataaaaaa gagaggacgt tcccctctta aaatcttatt
    42001 ttactgcttc tttcaaagca tctaccttat ctaaacgttc ccatggaaga tcaatatctg
    42061 tacgtcccat gtgaccgtaa gccgatgttt gacggtaaat tggacgctta aggtccagca
    42121 tttggataat ccctgcaggg cgaaggtcaa agatttgacg agccgctttt tcaagttgac
    42181 tttcagctac tgttcctgta ccgaaagtat cgatacgaac agaaacaggt tgcgcaacac
    42241 cgatagcata ggccaactgc acttctgcct tcttagcaag gtctgctgca acgatattct
    42301 tggcaatata gcgagccgca taagaggctg aacgatccac cttagtcgca tctttaccag
    42361 agaaggcacc accaccatga cgagagtagc caccataagt atctacaata atcttacgac
    42421 cagtcaaacc tgagtcccct tgaggaccac cgattacaaa acgacctgtc ggattgataa
    42481 agaattttgt cttatcatca agataagaag atggaataac ttctttgatg accttgtcaa
    42541 tcacatcttg atggatttgt tcattagtgg cctctggatc atgctgagta gaaataacga
    42601 ctgtatctac acgtaccgga cggtcatttt catcgtactc aactgtaact tgtgattttg
    42661 catctggacg gagatagcta atttctccag acttacgaag ttctgccaga cgacgaacca
    42721 atttatgact gagtgcaatt ggcaatggca tgagctcttc tgtttcatct actgcaaatc
    42781 caaacatgag cccttggtca cctgctccaa tcaagtccag tggatcttga tcagcatttc
    42841 cacgaacctc caaggcttcg ttaacacctt gagcgatgtc aggagattgt tccaccaaag
    42901 atgggtgtac tcccaccgtc tcagcagaaa atccatattc tgtattggta taaccaatct
    42961 ctgcaatggt atcacgaacc acacggttaa tatccacata ggcatttgta gaaatttcac
    43021 caaaaacgtg gacagaacca gtatatacag ctgtttcagc agcaacgtgc gcctctggat
    43081 cctttgctaa aatagcatcc aaaatcgcat ctgaaatttg gtctgcaatc ttatccggat
    43141 gcccctcaga tacagattca gacgtgaata atttacgctc tgacataaaa atgtcccccc
    43201 ttaaaaaata ttgttataga gttacaaagt actgatagga aaactcttcg taataaatac
    43261 ctaccatctt atcgggacta tataacttta tcattatacc atttttaatc gcaatttgca
    43321 gtctttaatg tagtgtttcg gtttagatag ttcgttctca taaataaaaa agttggagct
    43381 caatactcca acaatttcta ttaaaatgtt tggcgtttag ctttacgctc tgcacgaccg
    43441 cgagcgcgat tttcagcacg cttggtttta cggcgctttt catcaaccgc ccattgaatt
    43501 ttcttcttat aacccggttt gacttttttc tttttctttt taaccaaacc aatcatttcg
    43561 atatcaagtt tatcttgttt tttctcacgg ttggcacgac gatcacggtc ataggtatct
    43621 tgaaattccc cgtctttgac catcttagga ctaaacttga ttcccaattt ctccaactca
    43681 cggatatccg agtcatcact tggctgataa agggtaatag ctgtacctgg taggccattt
    43741 cgtccagtac gaccaacacg atgaacaaaa aaagataagt cttgcggaat ggcatcattg
    43801 atgacatggc tgacaccttc aatgtcaatc ccacgcgctg ctaaatctgt tgcgacaata
    43861 tactcaaaat ccagattttg cacctgattc atgattcgct tgcgttcacg aggggcaata
    43921 tctccatgga tttttgcaac cttcaagcct tgagcagtca gatatgaatg caattcatca
    43981 gcacgcgttt tagtgttaac aaaaatcatt gccaaatacg gctgcatcaa ctgagtcaac
    44041 tggtaaattt gagcattctt atcatgtccc ttggtcgaaa tcaaccaatt atcaatggtg
    44101 tcagaaataa ccgttttggt cttaattttc tccataacag gattggataa gtattttttc
    44161 aagaatggtt gcagtttttg tgggatagtc gctgagaaga ccatgaattg caagtctttt
    44221 ggaagactgc cagcaatctt atcaacagtt tccaagaatc ccatatccaa ggtcatatct
    44281 gcttcatcaa caacaaatgt cttggcttta tgaatagcta aatcaccaga tttaaccaag
    44341 tcgtagatac ggcctggtgt tccaataaca atatgaggct gattgcttgc caatttctca
    44401 atctggcgag ccttatccgt accacccaca taattaacca cacgaacttc gacatctgag
    44461 tgagctgaaa tctgacgcgc tacttggtaa atttgagtag ccaactcacg actcggtgca
    44521 gtaatcactg cttgtacact atcgctagct tcatctaatt gctggaaaat cggtaacaag
    44581 aaagtatgag tcttacctga acctgttttt gattctccta ctaggtcacg acctgccaaa
    44641 acaataggaa tcaacttgtc ttgcacctct gttggagttg taaattttaa ctccttcaag
    44701 gcttctctaa tatagttttt aaattgaaat ttcgtaaatg acataacatc ctcgattcta
    44761 tctatcttat caattatacc atattttgaa cattttcagt agtccgactc atctgaccta
    44821 tcacaaggct ctcaatttct ctaaatatag taaaatgaaa taagaatagg atgaatcgat
    44881 caggacagtc aaatcgattt ctaacaatgt tttagaagca gaggtgtact attctagttt
    44941 caatctacta tacctctctt atactaaaaa tcatacattt gctttctttc caaaatgcaa
    45001 aaagagaaga ccaaattggt cttctctcag ccttaaagct tgcgactcag atagatttgt
    45061 caaacagtca aacagttgct taagaatctt gtaaaagtcg aaagcttcta gaaaaattag
    45121 tacttaatca tctttccgct tgcgaccaag aagcaacact gctagacctg caagaagaga
    45181 gctagtcact agtccagtga gtgaaagtgg tgcagtacta cccgcatttg gcaatgtagc
    45241 ttgtttttcc ttttctcctg ctggaccttg agctggtgga ttctcttcag gttttcttgg
    45301 ttgttctgat tgatgtctat ctgcctgatt attatcagtt ccctgctctc cccctggatt
    45361 cactggtgga actggatttg gttgaggtgc tggttgtggc gttggtgccg gctgtggttg
    45421 tggactagga tcttgcttag cttcaaagac ccacttaccg acgaaggtta gatttgaccc
    45481 ctcttccact tcttggtaac ctaagaatgt ccatgtacca tttgcaacag caacttctac
    45541 aggcatcggt gcttctggaa cgaaagcaat cgctacagaa gaacttgtag tatatgttcc
    45601 actttgtggg agtaagctca atacttctgc tggcaagttg ttgtctgcgg ttgcact
//
LOCUS       DAVMCG010000014        41777 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVMCG010000014 DAVMCG010000000
VERSION     DAVMCG010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41777
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.014"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            161..2794
                     /gene="polA"
                     /locus_tag="VYP66_000925"
     CDS             161..2794
                     /gene="polA"
                     /locus_tag="VYP66_000925"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1850495.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIALIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2879..3316
                     /locus_tag="VYP66_000926"
     CDS             2879..3316
                     /locus_tag="VYP66_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1850496.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(3499..4509)
                     /locus_tag="VYP66_000927"
     CDS             complement(3499..4509)
                     /locus_tag="VYP66_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1850497.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            4658..5827
                     /locus_tag="VYP66_000928"
     CDS             4658..5827
                     /locus_tag="VYP66_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1850498.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTSQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5824..6594
                     /gene="recO"
                     /locus_tag="VYP66_000929"
     CDS             5824..6594
                     /gene="recO"
                     /locus_tag="VYP66_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1850499.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6591..7583
                     /gene="plsX"
                     /locus_tag="VYP66_000930"
     CDS             6591..7583
                     /gene="plsX"
                     /locus_tag="VYP66_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1850500.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            7589..7822
                     /locus_tag="VYP66_000931"
     CDS             7589..7822
                     /locus_tag="VYP66_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1850501.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            7868..8159
                     /locus_tag="VYP66_000932"
                     /pseudo
     CDS             7868..8159
                     /locus_tag="VYP66_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8362..8592
                     /gene="blpU"
                     /locus_tag="VYP66_000933"
                     /pseudo
     CDS             8362..8592
                     /gene="blpU"
                     /locus_tag="VYP66_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            9307..11460
                     /locus_tag="VYP66_000934"
     CDS             9307..11460
                     /locus_tag="VYP66_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1850502.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFAEEWTGVTLFMAPSPDYKPHKEQKNGLFSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGSVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            11473..12822
                     /locus_tag="VYP66_000935"
     CDS             11473..12822
                     /locus_tag="VYP66_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1850503.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLINQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            12992..13699
                     /locus_tag="VYP66_000936"
     CDS             12992..13699
                     /locus_tag="VYP66_000936"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1850504.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQGLK"
     gene            13756..17481
                     /locus_tag="VYP66_000937"
     CDS             13756..17481
                     /locus_tag="VYP66_000937"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1850505.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNVGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVAIVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELETALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEVANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            17574..19016
                     /locus_tag="VYP66_000938"
     CDS             17574..19016
                     /locus_tag="VYP66_000938"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1850506.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGKLKRHRDMGLLSEVFRNPANLDKLTGTGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEDRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSMTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            19053..20075
                     /locus_tag="VYP66_000939"
     CDS             19053..20075
                     /locus_tag="VYP66_000939"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1850507.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            20072..20617
                     /gene="purN"
                     /locus_tag="VYP66_000940"
     CDS             20072..20617
                     /gene="purN"
                     /locus_tag="VYP66_000940"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1850508.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            20701..21210
                     /locus_tag="VYP66_000941"
     CDS             20701..21210
                     /locus_tag="VYP66_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1850509.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            21235..22782
                     /gene="purH"
                     /locus_tag="VYP66_000942"
     CDS             21235..22782
                     /gene="purH"
                     /locus_tag="VYP66_000942"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1850510.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQKASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            22904..24166
                     /gene="purD"
                     /locus_tag="VYP66_000943"
     CDS             22904..24166
                     /gene="purD"
                     /locus_tag="VYP66_000943"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1850511.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELYQQKIEGLFYRTDIGSKAIK"
     gene            24569..25057
                     /gene="purE"
                     /locus_tag="VYP66_000944"
     CDS             24569..25057
                     /gene="purE"
                     /locus_tag="VYP66_000944"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1850512.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            25044..26135
                     /gene="purK"
                     /locus_tag="VYP66_000945"
     CDS             25044..26135
                     /gene="purK"
                     /locus_tag="VYP66_000945"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1850513.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            26145..26372
                     /locus_tag="VYP66_000946"
     CDS             26145..26372
                     /locus_tag="VYP66_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1850514.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVKAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            26435..27733
                     /gene="purB"
                     /locus_tag="VYP66_000947"
     CDS             26435..27733
                     /gene="purB"
                     /locus_tag="VYP66_000947"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1850515.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(27788..31726)
                     /gene="strH"
                     /locus_tag="VYP66_000948"
     CDS             complement(27788..31726)
                     /gene="strH"
                     /locus_tag="VYP66_000948"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1850516.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAVLQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(32041..32757)
                     /locus_tag="VYP66_000949"
     CDS             complement(32041..32757)
                     /locus_tag="VYP66_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1850517.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            33105..34892
                     /locus_tag="VYP66_000950"
     CDS             33105..34892
                     /locus_tag="VYP66_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1850518.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEYIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            34889..35365
                     /locus_tag="VYP66_000951"
     CDS             34889..35365
                     /locus_tag="VYP66_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1850519.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            35393..36298
                     /locus_tag="VYP66_000952"
     CDS             35393..36298
                     /locus_tag="VYP66_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1850520.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            36285..37100
                     /locus_tag="VYP66_000953"
     CDS             36285..37100
                     /locus_tag="VYP66_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1850521.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            37107..37511
                     /locus_tag="VYP66_000954"
     CDS             37107..37511
                     /locus_tag="VYP66_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1850522.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            37810..38976
                     /locus_tag="VYP66_000955"
     CDS             37810..38976
                     /locus_tag="VYP66_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1850523.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESLATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            39092..40129
                     /locus_tag="VYP66_000956"
     CDS             39092..40129
                     /locus_tag="VYP66_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1850524.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            40246..41459
                     /locus_tag="VYP66_000957"
                     /pseudo
     CDS             40246..41459
                     /locus_tag="VYP66_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
BASE COUNT        11641 a         8005 c         9961 g        12170 t
ORIGIN      
        1 gtgtactatt atagattcaa tatactatat tatagcacat ttttaaatct aggtttacta
       61 aattctctgg ctctatctat ttattcggaa aaagtttgaa aaatacttgc tctagctctt
      121 cccaatggta ttttttgatt ctttccttta taatgggtgt atggataaga aaaaattatt
      181 attgattgat gggtcttctg tagcttttcg ggcgtttttt gcgctgtatc agcagttgga
      241 ccgttttaag aatgcggctg gtttgcatac caatgcgatt tatggttttc agttgatgtt
      301 gagtcatttg ttggagcggg ttgagccgag tcatattttg gtggcttttg atgcgggaaa
      361 gacgaccttc cggacagaga tgtatgcgga ctataagggt ggtcgggcca agactcctga
      421 tgagtttcgt gagcaatttc ctttcattcg tgagttgctg gatcatatgg ggattcgtca
      481 ctatgagctg gctcagtatg aggcggatga catcattggg acgctggata agctagcaga
      541 gcaggatggt tttgatatta ccattgtcag tggggacaag gatttgattc agctgacgga
      601 tgagcatacg gtggttgaaa tttccaagaa aggtgtggct gagtttgagg cctttacgcc
      661 agattacctc atggaagaaa tgggcctcac accagctcag tttatcgatc tcaaggcgct
      721 catgggtgat aagtcggata atatccctgg ggtgaccaaa gtcggtgaaa agacgggtat
      781 taagctcttg ctggagcatg gttcgcttga ggggatttat gaaaatattg atggaatgaa
      841 gacttctaag atgaaggaaa atctcatcaa tgacaaggaa caggcctttt tgtctaaaac
      901 actagcgacc attgatacca aggcaccgat tgcgattggt ttagaggact tggtctatag
      961 tggtccagat gttgaaaatc ttgggaaatt ctacgatgag atgggcttca aacagctaaa
     1021 gcaggcttta aatgtgtcgt cagctgatgt gtctgagagt ttggatttta ctattgttga
     1081 ccaaatcagt caagatatgc tgagtgaaga gtctatcttc cactttgagc tttttggtga
     1141 gaattaccat acggataatt tggttggatt tgcctggtct tgtggggata agctctatgc
     1201 cacagacaag cttgagctgt tgcaagaccc gattttcaag gatttcttag aaaaaacatc
     1261 tctgagagtt tatgacttta agaaggttaa agttcttttg caacgttttg gtgtggattt
     1321 gcaggcgcct gcttttgaca tccgtttggc taaatacctc ctttcgactg tggaggacaa
     1381 tgaaattgcg accatcgcta gtctttatgg tcagacttac ttggttgatg atgaaacttt
     1441 ctacggtaag ggtgttaaaa aggccattcc tgaacgtgag aaattcttgg aacacttagc
     1501 ttgtaaactt gctgttttgg tagaaacaga gcctatttta cttgaaaaac tcagcgaaaa
     1561 tgggcaatta gagcttcttt atgatatgga gcaacctctg gcttttgtcc ttgccaagat
     1621 ggaaattgct gggattatgg tcaagaaaga gaccttgctt gagatgcagg ctgaaaatga
     1681 gcttgtcatt gaaaaactga ctcaagagat ttacgagctg gctggtgagg agtttaatgt
     1741 caactcgcct aagcagttgg gcgtgcttct ctttgagaaa ttgggacttc ctctagaata
     1801 cactaagaaa accaagacag gttattcgac agcagtggat gttttggagc gtctcgctcc
     1861 tattgctctg attgttaaga aaatcctgga ttaccgtcaa attgctaaga ttcaatctac
     1921 ttatgtaatt ggcttgcagg actggatttt ggctgatgga aagattcata ctcgctatgt
     1981 gcaggatttg acccagaccg ggcgtttgtc tagtgtggat ccaaacttgc aaaatattcc
     2041 tgcccgattg gaacaggggc gcttgattcg gaaggctttt gtgccagagt gggaggatag
     2101 tgtgctactc agctctgact attcacagat tgaattgcgc gttttggcgc atatttctaa
     2161 ggatgagcac ttgattaagg ccttccaaga gggggcagat atccatactt cgacagccat
     2221 gcgggtcttt ggcattgagc gtcctgatga tgtgactgca aacgaccgtc gcaatgccaa
     2281 ggcagttaac tttggagtgg tttatgggat ttcagacttt ggcttgtcta ataatttggg
     2341 aattagtcgt aaggaagcca aagcctacat tgatacctac tttgaacgtt ttccaggtat
     2401 taaaaactac atggatgaag tggtgcggga ggcgcgtgat aagggctatg tagagaccct
     2461 ctttaagcgt cgccgtgagt tgccagatat caattcgcgc aacttcaata ttcgtggttt
     2521 tgcggaacga actgctatca actcacctat ccagggttcg gcagcagata ttctcaagat
     2581 tgccatgatt cagctggata aagccttggt tgcaggtggt tatcagacta agatgctgtt
     2641 acaagtgcac gatgaaatcg tccttgaagt gcctaaatct gaattggtag agatgaaaaa
     2701 attggtgaaa caaaccatgg aagaagccat tcaactcagt gttcctctta tcgcagatga
     2761 gaatgaaggg gcaacctggt acgaggctaa ataaaaaggg ggctagtcct ccttttttgt
     2821 agtataattc tgcaaacctt ttcaaaatgt gctatactga tgaaaaagga ggatttctat
     2881 gagtcaagaa tttatcaatc caagtgatgg cgtgattcgt cagtatctcg caacgagtaa
     2941 aacccttgct gtggtgggtt tgtctgaccg tgaagaaaca accagcaatc gagtaacaaa
     3001 ggaaatgcag gctcggggct ataaaatcat cccagtcaat cccaaggcgg caggtggcga
     3061 aatcttgggt gaaaaggctt atgctagcct cgctgaaatt ccttttcctg tagatattgt
     3121 caatgtttat cgtcgcagtg aatttctgcc cgatgtggcg cgtgattttc tcaaagctga
     3181 tgccaagatt ttttgggcac agctaggact tgaaagttta gaagcgaaag agattttgcg
     3241 tgatggtgga tgtgatgata tcgtgatgaa tcgctgtatc aagagagaac atactcgctt
     3301 gattgaggaa gcataagaaa aaggtagctg atgggctacc ttttgtgtta tactcaatga
     3361 aaatcaaaga gcaaactagg aaactagccg cgggctgctc aaaacaccgt tttgaggttg
     3421 cagatagaac tgacgaagtc agtaacatat atacggcaag gcgacgttga cgtggtttga
     3481 agagattttc gaagagtgtt agaaaatgcc gataagggtc tgcataccaa gagtggtgag
     3541 gatgatggca atccagcaga tggctccaag aagaatggat tttccactgg atttgaccat
     3601 agcgaccaga ttggttttga gaccgatagc actcatggcc atgacaataa ggaatttaga
     3661 gagttctttg agaggagtaa agaaactact ggacacacct agagaggtga gtagtgtagt
     3721 gaggagagag gcaaggataa agtaaaggat aaaaagtggg aagacttttt tcagttgcag
     3781 gctttgcttg ttttcttgtt ggcgactttg ccagtaggat agaaagagcg tgatagggat
     3841 aatggccaaa gtacgtgtga gtttaacaat ggttgcagac tcgagggtat tgctttggta
     3901 aagactgtcc caagcgctgg cggcagccgt tacagaggaa gtgtcgttga ccgcagtccc
     3961 tgcaaagagg gcgaagcctt cattggatag atgaagccag gtgccgaggg ttggaaagat
     4021 gagcgcagcc aagacattga agaaaaagat aacggaaatg gcttgggcta cttccttttc
     4081 cttagcatca ataacgggcg ctgtcgctgc aatggcagaa cccccacaga tagaagaacc
     4141 tactccaacc aaggtagcca gttttgtatc cagggcaaag aaacgctgga agaggtaggc
     4201 aataatcaga gctattgaga tagtggacag gatgacaggg agtgaagatt ggccaactgc
     4261 gaagacctgc gagatattga gaccaaaacc aagcaagaca acggcatatt ggagcaactt
     4321 cttggaacta aaggtcaaac cagcatccag ttgtttatag gacgagagaa agggatgtag
     4381 gagcatgcct atgaaaatgg caaaaacggg cgcgccaatc acagggaaga atcctcctaa
     4441 gtaccaagat acgatagaaa tgagaaggca ggccaagata cctgctccat tttttgatag
     4501 aaatgacata aaaacctcca aataaaatct attaccatta tagacctata aacaggaaaa
     4561 gtaaaataga aagtggaaag ctatcctcta atgtattttt gcggtcgggg ggcttttgta
     4621 gtataataga gatacgtttt gaaagtagga ggtatctatg gacttaacta agcgctttaa
     4681 taaacagtta gataaaattc aagtttcgtt gattcgtcag tttgaccagg ctatttcgga
     4741 gattcctggg gtcttgcgtt tgaccttggg ggaacctgat tttacaacgc cagaccatgt
     4801 caaggaggcg gccaagcgag cgattgatca gaaccaatcc tactatacag ggatgagtgg
     4861 tctgctgact ctacgtcagg cagctagtga ctttgttaag gaaaagtacc aactggacta
     4921 tgctcctgaa aatgaaatct tggttacaat tggggcgaca gaggctttat ctgcgacttt
     4981 gacggctatt ttggaagagg gagacaaggt acttttgcca gctcctgctt atccaggcta
     5041 tgaaccgatt gttaacttag ttggggcaga aattgttgag attgatacga ctgaaaatgg
     5101 ttttgtcttg actcctgaga tgttggagaa ggccattttg gagcagggtg ataagctcaa
     5161 ggcggttatt ctcaactatc cagccaatcc gacaggaatt acctacagtc gagagcagtt
     5221 agaggccttg gcagctgttt tacgcaagta cgaaattttt gttgtctgtg atgaggttta
     5281 ctcagaattg acctacacag gcgaagccca tgtgtctcta ggaacgatgt tgagagacca
     5341 ggctattatt atcaatggtt tgtctaaatc gcatgccatg acaggttggc gtttggggct
     5401 gattttcgct cctgcggcct tcacatccca gttaatcaag agtcaccaat acttggtcac
     5461 tgccgcaaat accatggcgc aacatgctgc ggtagaagcc ttgacggctg gtaaaaatga
     5521 tgcggagccc atgaagaagg aatatatcca gcgtcgggac tatatcatcg aaaaaatgac
     5581 tgctcttggt tttgagatta tcaaaccaga cggtgccttc tatatttttg ctaaaattcc
     5641 agcgggctac aatcaagact cctttgcttt tctgaaggat tttgctcaga agaaggccgt
     5701 tgcctttatc cctggtgcag cctttggacg ttacggggaa ggctacgtcc gcctatctta
     5761 tgcagccagc atggagacta tcaaagaagc catgaaacga cttgaggagt atatgagaga
     5821 agcatgattc agtctatcac gagtcaaggc ttggtgcttt acaatcgcaa ttttcgtgag
     5881 gatgacaagc ttgtcaaaat ttttacagag caggttggca aatgcatgtt ttttgtcaaa
     5941 cacgctggtc agtctaagct ggcgcctgtt attcagccct tggtgctggc acgatttctc
     6001 ttgcgaatca atgatgacgg actcagttac atcgaagact atcatgaggt catgactttt
     6061 cccaagatta atagtgacct ctttgtcatg gcctatgcga cctatgtggc agctcttgca
     6121 gatgctagtt tgcaggacaa tcagcaggat gctcccttgt ttgctttttt gcaaaagact
     6181 ttggagttga tggaagcagg cttggattat caggttttga ccaatatttt tgaaattcaa
     6241 attttgactc gatttggaat cagcctcaat tttaatgagt gtgtcttctg ccatcgggtt
     6301 ggtcaggctt ttgacttttc tttcaaatat ggagcctgtc tctgtccaga gcattatcat
     6361 gaggatgaga gacgttgcca tctcaatccc aatatcccct atctgctcaa tcaatttcaa
     6421 gctattgatt ttgagacttt ggagaccatt tcgctcaagc ctggaatcaa gcaagagcta
     6481 cgccaattta tggatcaact atatgaagag tacgttggga ttcacctaaa atcaaagaaa
     6541 tttattgatt ccctagcaga ctggggacaa ttactaaaag aggaaaagaa atgaaaaaaa
     6601 tcgcagtaga tgccatgggg ggcgattacg cacctcaggc catcgttgag ggtgtcaatc
     6661 aagccctatc tgacttttca gatatcgagg ttcaactcta cggagatgaa gctaaaatca
     6721 agcaatatct gacagcgaca gagcgcgtca gcattatcca tacggatgag aagattgatt
     6781 cggatgatga acctacgaga gctattcgga ataagaaaaa tgccagtatg gtattggcag
     6841 ccaaggctgt caaagatggt gaagcagacg ctgtcctttc ggctgggaat acaggtgctt
     6901 tgttggctgc tggattcttc atcgtgggtc gtatcaagaa tatcgaccgt cctggactta
     6961 tgtcaacatt gccgactgta gatgggaaag gttttgacat gcttgacctc ggtgctaatg
     7021 cagaaaatac agcccagcac ctccatcaat acgctgtcct aggttctttc tatgccaaga
     7081 atgttcgtgg cattgcgcaa ccacgtgttg gtttgctcaa caacggaaca gagagtagca
     7141 agggcgaccc gcttcgtaag gaaacttatg aattactggc ggctgatgaa agtttgaact
     7201 ttatcggaaa cgtggaagcg cgtgatttga tgaatggtgt tgcagatgtt gttgtggcag
     7261 atggtttcac gggaaacgct gtgctcaaat ccatcgaagg gacagctatg ggaatcatgg
     7321 gcttgctcaa gacagctatt acaggtggtg gtcttcgagc gaaactaggt gccctccttc
     7381 tcaaggacag cctcagaggt ttgaaaaaac agctcaatta ttcagatgtt ggtggagcgg
     7441 tcttgtttgg tgtcaaggca cctgttgtca agactcatgg ctcaagcgat gccaaggctg
     7501 tttatagtac gattcgccag attcgtacca tgctagaaac agaagtagtt gcccagactg
     7561 cgcgtgaatt ttcaggagaa taaaagagat gaaagaaaaa gaaatttttg acagtattgt
     7621 gaccattatc caagagcgac agggagagga ctttgtcgtg acagaatcct tgagtctgaa
     7681 agacgacttg gatgctgact cagttgattt gatggagttt atcttgacgc tggaggatga
     7741 atttagtatc gaaatcagcg atgaggaaat tgaccaactc caaagtgtag gagatgtggt
     7801 taaaatcatt caaggaaaat agcaatcgga gttccaagtc aacggaagta gatggttttt
     7861 agaaatgaga aatatcggac aagctggtaa aatcttggct gacagtggtt atcaagggct
     7921 tatgaagata tatcctcaag cacaaacttc cacgtaaatc cagcaaactc aagccgctaa
     7981 cagttgaaga taaagcctgt aatcatgcgc tatctaagga gagaagcaag gttgagaata
     8041 tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat catcgtaaac
     8101 gcttcggatt acgaatgaat ttgattgctg gtattatcaa tcatgaacta ggattctagt
     8161 tttgcaggaa gtctaatagt aaaaaagtga ttagaaaaca tcttttttaa aaatagagat
     8221 gattttgaaa caaaaaagct aattcaagac gtttcgatgc caattcaaga tttggatgaa
     8281 aaaaattaat agatactgtt atactaaact tgtcaagttt gtaacaagac aaatattaaa
     8341 aataaaaaag aggtattcgt tatgaataca aaaaagatgt cacaatttga aattatggat
     8401 actgagatgc ttgcttgagt tgaaggtggc ggatgcaatt ggggagattt tgccaaagca
     8461 ggtgttggag gaggagtagc acgaggtctt cagctaggaa ttaaaacaag aacatggcaa
     8521 ggtgcagcaa ctggtgctgc gggaggagct atacttggag gtgtggccta tgaagcgaca
     8581 tgttggtggt aattatggat tttaaaagtt ttattattgg tttagtagtt ggtatatttg
     8641 gtccttatat ggatgattta attagaaaaa aatttttaaa gtcttcggag aagaaaacag
     8701 aaaaatctgt taaaaaataa tcaaaactat aaatgatgaa tctgaatcaa aattattttg
     8761 cgcatgtaaa gaggagtctt atagtaacga gtcaaaaaag gagtaactat gaatcgtaat
     8821 ttagaacggt gttatctatt ctgactaggg atagatcata ccataggtag cttagaaata
     8881 gcagagacat tagaaattga agtaataaat aggatgtcgt aagtgttact atcaatgatt
     8941 tatttgtttc aagcttgcct agggtgtcag taaaaaatca ttttcctttc aatagcatat
     9001 ttttagtggg caggactctt gttctgccta tttttttatc caaaaagtgc agttgggagg
     9061 gagataggct catttgggaa ggaagtccag tttttgttta gtgattgggg taagatagtt
     9121 gttatcagat gagtttatat tcttcgaaaa tcaaattcaa accacgtcaa cgtcgccttg
     9181 ccgtatatat gtgactgact tcgtcagtcc tatctacaac ctcaaaacag tgttttgagc
     9241 agcctgcggc tagtttccta gtttgctctt tgattttcat tgagtattag ggaaaaggag
     9301 atgaatatga aatttgggaa acgtcactat cgtccgcaag tggatcagat ggactgcggt
     9361 gtagcttcat tagccatggt ttttggctac tatggtagtt attatttttt ggctcacttg
     9421 cgagaattgg ctaagacgac catggatgga acgacggctt tgggcttggt caaggtggca
     9481 gaggagattg gttttgagac gcgagccatt aaggcggata tgacgctttt tgacttgccg
     9541 gatttgactt ttccttttgt tgcccatgtg cttaaggaag ggaaattgct ccactactat
     9601 gtggtgactg ggcaggataa ggatagcatt catattgccg atccagatcc cggggtgaag
     9661 ttgaccaaac tgccacgtga gcgttttgcg gaagaatgga caggagtgac tctttttatg
     9721 gcacctagtc cagactacaa gcctcataag gaacaaaaaa atggtctgtt ctcttttatc
     9781 cctatattag tgaagcagcg tggcttgatt gccaatatcg ttttggcaac actcttggta
     9841 accgtgatta acattgtggg ttcttattat ctgcagtcta tcattgatac ctatgtgcca
     9901 gatcagatgc gttcgacact agggattatt tctattgggc tagtcatcgt ctacatcctc
     9961 cagcaaatct tgtcttacgc tcaggagtat ctcttgcttg ttttggggca acgcttgtcg
    10021 attgacgtga ttttgtccta tatcaagcat gtttttcacc tccctatgtc cttctttgcg
    10081 acacgcagga caggggaaat cgtgtctcgt tttacagatg ctaacagtat catcgatgcg
    10141 ctggcttcga ccatcctttc gattttccta gatgtgtcaa cggttgtcat tatttccctt
    10201 gttctatttt cacaaaatac caatctcttt ttcatgactt tattggcgct tcctatctac
    10261 acagtgatta tctttgcctt tatgaagccg tttgaaaaga tgaatcggga taccatggaa
    10321 gccaatgcgg ttctgtcttc ttctatcatt gaggacatca acggtattga gactatcaag
    10381 tccttgacca gtgaaagtca gcgttaccaa aaaattgaca aggaatttgt ggattatctg
    10441 aagaaatcct ttacctatag tcgagcagag agtcagcaaa aggctctgaa aaaggttgcc
    10501 catctcttgc ttaatgtcgg cattctctgg atgggggctg ttctggtcat ggatggcaag
    10561 atgagtttgg ggcagttgat tacctataat accttgctgg tttactttac caatcctttg
    10621 gaaaatatca tcaatctgca aaccaagctt cagacagcgc aggttgccaa taaccgtcta
    10681 aatgaagtgt atctagtagc ttctgagttt gaggagaaga aaacagttga ggatttgagc
    10741 ttgatgaagg gagatatgac cttcaagcag gttcattaca agtatggcta tggtcgagac
    10801 gtcttgtcgg atatcaattt aaccgttccc caagggtcta aggtggcttt tgtggggatt
    10861 tcagggtcag gtaagacgac tttggccaag atgatggtta atttttacga cccaagtcaa
    10921 ggggagatta gtctgggtag tgtcaatctc aatcagattg ataaaaaagc cctgcgccag
    10981 tacataaact atctgcctca acagccctat gtctttaacg gaacgatttt ggagaatctt
    11041 cttttgggag ccaaggaggg gacgacacag gaagatatct tacgggcggt cgaattggca
    11101 gagattcgag aggatatcga gcgcatgcca ctgaattatc agacagaatt gacttcggat
    11161 ggggcaggga tttcaggtgg tcaacgtcag agaatcgctt tggcgcgtgc tctcttgaca
    11221 gatgcgccgg tcttgatttt ggatgaggcg actagcagtt tggatatttt gacagagaag
    11281 cggattgtcg ataatctcat ggctttggac aagaccttga ttttcattgc tcaccgcttg
    11341 actattgctg agcggacaga gaaggtggtt gtcttggatc agggcaagat tgtcgaagaa
    11401 ggaaagcatg ctgatttgct tgcacagggt ggcttttacg cccatttggt caatagctag
    11461 aaagaggaga ggatgaaacc agaattttta gaaagtgcgg agttttataa tcgtcgttac
    11521 cataattttt ccagtagtgt gattgtaccc atggcccttc tgctcgtgtt tttacttggc
    11581 tttgcaactg ttgcagaaaa ggagatgagc ttgtccacta gagctactgt cgaacctagt
    11641 cgtatccttg caaatatcca gtcaactagc aacaatcgta ttcttgtcaa tcatttggaa
    11701 gaaaataagc tggttaagaa gggggatctt ttggttcaat accaagaagg ggcagagggt
    11761 gtccaagcgg agtcctatgc cagtcagttg gacatgctaa aggatcaaaa aaagcaattg
    11821 gagtatctgc aaaagagcct gcaagaaggg gagaaccact ttccagagga ggataagttt
    11881 ggctaccaag ccacctttcg cgactacatc agtcaagcag gcagtcttag ggctagtaca
    11941 tcgcaacaaa atgagaccat cgcgtcccag aatgcagcag ctagccaaac ccaagccgaa
    12001 atcggcaacc tcatcaatca aacagaggct aaaattcgcg attaccagac agctaagtca
    12061 gctatggaaa caggtgcttc cttggccagt cagaatctag cctactctct ttaccagtcc
    12121 tacaagtctc agggcgagga aaatccccaa actaaggttc aggcagttgc acaggttgaa
    12181 gcacagattt ctcagttaga atctagtctt gctacttacc gtgtccagta tgcaggttca
    12241 ggtacccagc aagcctatgc gtcagggtta agcagtcaat tggaatccct taaatcccaa
    12301 cacttggcaa aggttggtca ggaattgacc cttctagccc agaaaatctt ggaggcagag
    12361 tcaggtaaga aggtacaggg aaatctttta gacaagggga aaattacggc aagtgaggat
    12421 ggggtgcttc atcttaatcc tgagaccagt gattctagca tggttgcaga aggtgcccta
    12481 ctagcccaac tttatccatc tttggaaaga gaagggaaag ccaaactcac agcctatcta
    12541 agttcaaaag atgtagcaag aatcaaggtc ggtgattctg ttcgctatac tacgactcat
    12601 gatgccggga atcaactttt tctagattct actattacaa gtattgatgc gacagctact
    12661 aagactgaga aagggaattt ctttaaaatc gaggcggaga ctaatctaac ttcggagcag
    12721 gctgaaaaac ttaggtacgg ggtggaaggc cgtctacaga tgattacggg caagaaaagt
    12781 tacctacgtt attatttgga tcaatttttg aacaaagagt aatgttcgtg tttttagagt
    12841 taaataattt ttaaactgtg agaaagattc ttcttgcagt tttttcttta caatttttga
    12901 aaaacatctg ctatttattc ggttgaattc ttgtgttttt tggttttttg tggtaaaatg
    12961 tgctcaagta atacgaaagg cgaactttaa aatgtcaaaa caattgatct attcgggaaa
    13021 agctaaagat atctatacaa ctgaggatga aaatcttatt atttcaactt acaaggacca
    13081 ggcgactgct ttcaacggtg tcaagaagga gcagattgca ggtaagggag tcttgaataa
    13141 tcagatttca tcttttattt ttgagaaatt aaatgcggct ggtgtggcga ctcactttgt
    13201 ggagaaactt tcagacacgg aacaactcaa taaaaaggtt aagattattc ctttggaagt
    13261 cgtgctccgc aactatactg ctggttcctt ttcaaaacgt tttggtgtgg atgagggaat
    13321 cgccttggag actccgattg tcgaatttta ctacaaaaat gatgatttgg atgatccatt
    13381 tatcaatgat gagcatgtga aattcctaca gattgcgggt gaccagcaga ttgcctactt
    13441 gaaggaagaa acgcgtcgta tcaatgaact attgaaagtc tggtttgctg agattgggct
    13501 taaattgatt gactttaagc tagagttcgg ttttgacaag gatggcaaga ttatcttggc
    13561 agacgaattt tcaccagata actgccgctt gtgggacgct gatggcaacc acatggataa
    13621 ggatgttttc cgtagaggat tgggagaact aaccgacgtt tatgagattg tttgggaaaa
    13681 gttgcagggt ttaaaataac aacctcaagg ctgtttggga atattgcaag agctgaaata
    13741 aaggaataag aattgatgga taaacgtatt tttgttgaaa aaaaggctga ttttcaggtc
    13801 aagtcagaga gtttggttag agagctccag cacaacgtgg gactgtcaag cttgaaaagt
    13861 attcgtattg tgcaagtata tgatgtattt gacttggctg aggacttgtt tgcacctgca
    13921 gagaagcaca ttttctctga gcagggaacc gaccatgttt tagatgaagt atctgtgcag
    13981 gcggatcttg ctaactatgc tttctttgcc attgaaagtc tgccagggca gtttgaccag
    14041 cgtgcagctt cgtcacagga agccttgctt ttgttgggaa gttcgagtga cgtgacagtc
    14101 aacacagccc aactttactt ggtgaataaa gatattgatg cgactgagtt ggaagctgtc
    14161 aaaaactacc tgctcaatcc agttgattct cgtttcaagg atatcacgac agggattgcc
    14221 aagcaggagt tttcagagtc agacaagacc attccaaaat tgactttctt tgaaagctat
    14281 acagcagaag actttgctcg ctacaaggcc gagcaaggga tggccatgga agtggatgat
    14341 ttgctcttta tccaagacta ctttaagtca atcgggcgcg tgccaactga gactgaactc
    14401 aaggttttgg acacttactg gtctgaccac tgccgtcata cgacttttga gacagagttg
    14461 aaacacatcg acttttcagc ttctaaattt caaaagcaat tgcagtcaac ctatgacaag
    14521 tatattgcca tgcgcgagga gttaggtcgg tctgaaaaac cacaaacctt gatggatatg
    14581 gcgactattt tcggtcgtta tgagcgtgct aacggacgat tggatgatat ggaagtctct
    14641 gacgaaatca atgcctgctc agttgaaatt gaagtggatg ttgatggtgt caaggaacct
    14701 tggctcctca tgtttaaaaa tgaaacccac aaccatccaa cagaaattga gccatttggt
    14761 ggagcggcta cctgtatcgg tggagctatt cgtgatccgt tgtcaggccg ttcctatgtt
    14821 taccaagcca tgcgtatttc aggtgctggt gatattacag caccgatttc ggaaactcgt
    14881 gctgggaaat tgccacaaca agtcatttct aaaacagcag ctcatggtta ttcttcatat
    14941 ggtaaccaga ttgggcttgc cacaacctac gttcgtgaat acttccaccc aggctttgta
    15001 gctaaacgta tggaacttgg tgccgttgtt ggtgcggctc ccaagggcaa tgttgtccgt
    15061 gaaaaacctg aagcaggtga tgtgatcatc cttctcggag gcaaaacagg tcgtgatggt
    15121 gtcggtggtg cgacgggctc ttctaaggtt caaacagttg agtctgtaga gactgctggt
    15181 gctgaggttc aaaaaggaaa tgccatcgaa gaacgcaaga ttcagcgcct cttccgtaat
    15241 ggcaatgtca ctcgtctgat caagaagtcc aatgactttg gggcaggcgg cgtctgtgtg
    15301 gctatcggtg aattggcaga cggtcttgaa atcgacctca acaaggtgcc tcttaaatac
    15361 cagggcttga atggtacaga aattgccatc tctgaatcac aagaacggat ggcggtcgtg
    15421 gttcgtcctg aagatgtgga tgccttcgtt gccgaatgta acaaagaaaa tattgatgct
    15481 gttgtggtgg cgatagtaac tgaaaaacca aatcttgtca tgcactggaa tggtgagaca
    15541 atcgttgact tggagcgtcg tttccttgac accaatggtg tgcgcgtggt tgtcgatgcc
    15601 aaagttgtgg acaaggatgt caaactccca gaagagcgtc aaacatctgc tgaaacactg
    15661 gaatcagata cccttacggt tctatctgac ctcaaccatg caagtcaaaa aggattacag
    15721 actatctttg actgctctgt tggacgctca acggttaatc acccacttgg tggtcgttac
    15781 caactcacac caactgaggc atctgtgcag aaattgccag ttcaacacgg tgtgactcat
    15841 actgcgtcgg tcattgctca aggtttcaac ccatatgtag ctgaatggtc tccataccac
    15901 ggtgctgctt atgcggttat cgaagcaact gctcgtttgg tggctgctgg tgccaactgg
    15961 tccaaggctc gtttctctta ccaagagtat ttcgagcgta tggataaaca agcagagcgt
    16021 ttcggtcagc cagtagctgc tcttctaggt tctattgaag cacaaattca gcttggcttg
    16081 ccatctatcg gtggtaagga ctccatgtct ggtacctttg aagaattgac cgttccgcca
    16141 accttggttg cctttggggt gacgacggca gatagccgta aggtgctctc tccagaattt
    16201 aaagctgttg gggaaaatat ctactacatc ccaggtcaag ccctctctgc agagattgat
    16261 tttgacttga ttaagaaaaa ttttgctcag tttgaagcca tccaagctga ccataaagtg
    16321 acatctgcat cagctgtcaa atacggtggt gtagttgaaa gtttggctct tgctaccttt
    16381 ggaaactata ttggtgcaga ggtgaccttg cctgaacttg aaacagcttt gacagctcaa
    16441 ttaggcggct ttgtcttcac atctcctgaa gaaattgctg gagtagagaa ggttggacaa
    16501 acgaaagcag actttacact gactgtcaac ggtgtgaagc tagatggaca caagcttgac
    16561 agtgcatttc aagggacatt ggaagaagtt tacccaacag aatttaccca agcgaaagaa
    16621 ctagaagaag taccagctgt ggcatcagat gttgtgatta aagccaaaga aaaggttgaa
    16681 aaacctgtgg tttacatccc agtctttcca ggaaccaact cagaatatga ttcagctaag
    16741 gccttcgaaa aagaaggtgc agaggtcaat ttggtgccat tcgtgacctt gaatgaagaa
    16801 gctattgtca agtcagttga aactatggtt gacaatatcg acaagactaa tattctcttc
    16861 tttgctggtg gattctcggc tgcggatgaa ccagatggtt cagctaagtt tatcgtcaat
    16921 atcctgctta atgaaaaagt gcgtgtggct attgatagct ttatcgcccg tggtggtttg
    16981 attatcggta tttgtaatgg attccaagcc ttagtcaaat cgggtctcct accctacgga
    17041 aactttgaag ttgctaacag tactagccca accctcttct acaatgatgc caaccaacac
    17101 gtggccaaga tggtggaaac tcgcattgcc aataccaact caccatggtt ggctggtgtg
    17161 caagtgggcg atatccacgc tattcctgtt tcgcacggtg aagggaagtt tgtcgtgacg
    17221 gctgaggaat ttgcagagct ccgtgacaat ggacaaattt tcagccaata cgttgacttt
    17281 aacggtaaac caagtatgga ttctaagtac aatccgaatg gttctgtcca tgccatcgaa
    17341 ggaattacca gcaagaatgg tcaaatcatc ggtaagatgg gccactcaga acgttatgag
    17401 gacggtcttt tccaaaatat cccaggcaat aaagaccagc acctgttcgc gtcagcggtt
    17461 aaacatttca ctggaaaata agacttacag attttctaat agatagtatc agtaatgtaa
    17521 aagtcatgta aatctagctc ttgatgatta caaatgaaaa ttaggtataa aaaatgacat
    17581 acgaagtaaa atctcttaat gaagaatgtg gtgttttcgg tatttgggga catccagatg
    17641 ctgctaagtt gacctatttt ggactccaca gtcttcagca ccgtggtcaa gagggggcag
    17701 gaatcctctc caatgaccaa ggaaaactaa agcgccatcg tgacatggga cttttatcag
    17761 aagtcttcag aaatcctgct aatttggata aattgacagg gactggtgcg attgggcatg
    17821 tgcgttatgc gactgctggc gaagcttctg tagataacat ccagcccttc ctcttccgtt
    17881 ttcacgatat gcagtttggc ttggctcata atgggaatct gaccaatgca gcctctctca
    17941 agaaagaatt ggaagataga ggagcaattt tcagtgcgac ttcggattcg gaaatcttgg
    18001 ctcatctcat tcgtcgcagt cataatccta gcctgatggg caaaatcaag gaagcgctca
    18061 gccttgtcaa aggtggtttt gcctatatct tgctgtttga ggacaagttg attgcggctc
    18121 ttgaccccaa tggtttccgt ccgctttcta tcgggaaaat ggctaatgga gcagttgttg
    18181 tatcttctga aacctgtgct tttgaggtta ttggtgccga gtggattcgt gatttgaagc
    18241 caggtgagat tgtgatcatt gatgacgagg gcattcagta tgacagctat acagatgata
    18301 cccagttggc gatttgttct atggagtata tctactttgc tcgccctgat tctaatatcc
    18361 acggtgtcaa tgtccatacg gcacgtaaga gaatgggagc gcaattggcg cgagaattta
    18421 agcatgaggc agatattgta gttggtgtgc ccaattcttc cctaagcgcg gctatgggat
    18481 ttgcggaaga atcaggctta ccaaatgaaa tgggtctgat caaaaaccaa tacacccagc
    18541 gaacttttat ccaaccgact caagaattgc gggagcaagg agtgcggatg aaactgtctg
    18601 ctgtttcggg tgttgtcaaa ggcaaacgtg tggtcatggt ggatgattcc attgtacgtg
    18661 gaacaacctc tcgtcgtatc gttcagctct tgaaagaagc gggtgcgact gaggttcacg
    18721 ttgccattgg aagtcctgca ctagcgtatc catgtttcta cgggattgat atccagaccc
    18781 gtcaggagct gattgcagcc aatcatacgg tcgaagaaac tcgccaaatc attggtgcgg
    18841 acagtatgac ttatctttca attgatggct tgattgagtc gattggtatc gaaacagatg
    18901 cgccgaacgg tggtctctgt gtcgcttact ttgacggtga ctacccaacg cctctctatg
    18961 actacgaaga agactatcgt agaagtttgg aagaaaagac cagtttttac aagtaggcga
    19021 cagattctcc attaaagaaa aggaaaaaac aaatgacaaa taaaaatgca tatgcccagt
    19081 cgggtgtgga tgttgaagcg ggttatgaag ttgttgaacg gattaaaaag cacgtggccc
    19141 gtacggagcg tgcaggtgtc atgggagctc ttggtggctt tggtggtatg tttgaccttt
    19201 ccaagactgg ggttaaagaa cccgtcttga tttcagggac tgacggtgtc ggaaccaagc
    19261 tcatgttggc tatcaagtac gacaagcacg ataccatcgg gcaggactgt gtggccatgt
    19321 gtgtcaacga catcattgct gcaggtgcgg aacccctcta ttttctcgac tacgtagcga
    19381 cagggaagaa tgaaccagct aagctagaac aagtggttgc tggtgtggca gaaggttgtg
    19441 tgcaggctgg tgctgccctc atcggtgggg aaacggctga aatgccgggc atgtacggcg
    19501 aagacgacta tgacttggct ggttttgcgg tcggtgtggc tgaaaaatct caaatcattg
    19561 acggttcaaa ggtggtagag ggagatgttc ttctcggact tgtttcaagt gggattcact
    19621 caaatggtta ctctttggtt cgtcgtgtct ttgcggatta cacaggtgag gaagtcctac
    19681 cagaattgga aggcaagaaa cttaaggaag ttctacttga gccgactcgt atctatgtca
    19741 aggctgtctt gccgctcatc aaagaagagt tggtcaacgg cattgcccac atcacaggtg
    19801 gtggctttat cgaaaatgtc cctcgtatgt ttgcagatga cctagctgct gaaattgatg
    19861 aaagcaaagt tccagtgctt ccaattttca aagcccttga aaaatacggt cagattaaac
    19921 acgaagaaat gtttgaaatc ttcaatatgg gtgtgggact catgttggcg gtcagccctg
    19981 aaaatgtaga gcgtgtaaaa gaattgttgg atgaagcagt ctatgaaatt ggtcgcatcg
    20041 tcaagaaaga aaacgaaagt gtcattatca aatgaaaaaa atagcggttt ttgcctctgg
    20101 taatggctca aattttcagg tgattgccga agaatttcca gtggagtttg tcttttcaga
    20161 ccatcgtgat gcctatgtgc ttgagcgtgc aaagcagctc ggcgttctgt cctatgcttt
    20221 tgaactcaag gagtttgaga gcaaggcaga ctacgaagca gcccttgtcg aactcttgga
    20281 agaacaccag attgacttgg tttgcctagc aggctacatg aaaatagttg gaccaacctt
    20341 attgtcggct tatgaaggtc ggattgtcaa cattcatcca gcctacttgc cagaatttcc
    20401 aggagctcat gggattgagg atgcttggaa tgctggcgtg ggtcagtctg gtgtgaccat
    20461 tcactgggtg gattcgggtg tggatacagg ccaggtcatc aaacaggttc gtgtgccacg
    20521 actagctgat gataccattg acagatttga agctcgcatc catgaagcag agtacaggtt
    20581 gtatccggaa gtagtgaagg ctctatttac agattgactt tttgatgatt catatgatat
    20641 ctttgatttt aaattggagt cagtgtttgt tgaagacggc ttcaaacgga ggtatttgta
    20701 atgttagaat ctaaaaaaac aactcgatat gtattttatg tctatctgat gttattaact
    20761 tggggaatct tatttaagtt tgaaacaaat cctgaattta tagcattttt cttagctcca
    20821 aggtatatca attggattcc attttcagaa ccactaatag tcgatggaaa aattgttttt
    20881 gctgaaatgt tatttaatct gatttccttt attccattag gtgtttgttt ccctttgata
    20941 aaaactaatt tatctagttt aagaatagtc gggacaggtt tcttgattag tttattgttt
    21001 gagtgcttac agtatatttt agcaataggt ataacagata taacggattt gactttaaat
    21061 acgctaggtg tctgtgtagg cttactgatt tatcaaattt ttataagagt gttcaaatca
    21121 cagactagaa aatggatcaa tatcttaggt atgcttagcc ttggttttgc ttatcttgtt
    21181 ttactgttac tgcatttaat tggtgtttaa ctaatgatta aaaaggagaa tataatgact
    21241 aaacgcgtct taatcagcgt ctcagacaaa gcgggcattg ttgaatttgc ccaagaactc
    21301 aaaaaacttg gttgggagat tatctcaaca ggtggaacta aggttgccct tgataatgct
    21361 ggggtggata ccattgctat cgatgatgtg actggtttcc cagaaatgat ggacggtcgt
    21421 gtgaagaccc tccacccaaa tatccacgga gggcttctcg ctcgtcgtga cttggatagc
    21481 cacttggaag cggctaagga caacaagatt gagctcattg accttgtggt ggtcaacctt
    21541 tacccattta aggaaactat ccttaaacca gatgtgactt atgctgatgc agttgaaaat
    21601 atcgatattg gtgggccgtc tatgcttcgt tcagcagcga aaaatcatgc cagtgttaca
    21661 gttgtggtag atcctgctga ctacgctgtg gttttggacg aattggcagc aaacggcgaa
    21721 acctcttatg aaactcgcca acgtttagca gccaaagtat ttcgtcacac agcggcttat
    21781 gacgccttga ttgcagaata cttcacagct caagtgggtg aaagcaagcc tgaaaaactc
    21841 actttgactt atgacctcaa gcaaccaatg cgttacggtg agaatcctca acaagacgcg
    21901 gacttttacc agaaagcttt gcctacagac tactccattg cttcagccaa acagctcaac
    21961 gggaaagaat tgtcatttaa taatatccgt gatgcagatg ctgctatccg tatcatccgt
    22021 gacttcaaag atagtccaac cgttgtggct ctcaaacaca tgaatccatg tggaattggt
    22081 caagctgatg acatcgagac tgcttgggac tacgcttatg agtctgaccc agtgtctatc
    22141 tttggtggga ttgtcgtcct caaccgtgag gtggatgctg cgacagctga gaagatgcac
    22201 ggcgttttcc tcgaaatcat cattgcacca agctatacgg atgaagcgct agccattttg
    22261 atcaataaaa agaaaaactt gcgtatcctt gccttgccat ttaatgctca aaaggctagc
    22321 gaagtggaag cagaatacac aggtgtagtc ggtggacttc tcgtgcaaaa tcaagacgtg
    22381 gtcaaggaaa gcccagctga ctggcaagtg gtgaccaaac gtcagccaac tgagacagaa
    22441 gcgactgctc ttgagttcgc ttggaaggct atcaagtacg tcaaatcaaa tggtattatc
    22501 gtgaccaacg accacatgac acttggtgtt ggtccaggtc aaaccaaccg tgtggcttct
    22561 gttcgccttg ccattgacca agccaaagat cgtctgaacg gggcggtcct tgcttcagat
    22621 gccttcttcc catttgcgga taacgtggaa gaaatcgcca aagcaggaat taaggccatc
    22681 atccagcccg gtggctctgt ccgtgaccaa gaatccatcg aagcagcgga taaatacggc
    22741 ttgactatgg tctttacagg tgtgagacat tttagacatt aagaagataa aagggaagaa
    22801 aacagtttct ttcctttttt ggcttaaaat gctaactgaa acaagattaa aacgaacttt
    22861 tttgatataa tattggtaaa taattcgcaa aagaggttga ggaatgaaac tgcttgttgt
    22921 cggttcgggt ggtcgtgagc atgcgattgc taaaaagtta cttgaatcaa aagacgttga
    22981 aaaagtcttt gtagctcctg ggaatgatgg gatgactctg gatggtttgg aattggtaaa
    23041 tatctctatt tccgaacatt ctaaattgat tgacttcgca aagaccaatg atgttgcttg
    23101 gacctttatc ggtccagatg atgcccttgc tgctggtatc gtggatgatt ttaaccaagc
    23161 tgggcttaag gcctttggtc cgactagggc tgcagcggag ctggagtggt ccaaggattt
    23221 tgccaaggaa atcatggtca aatatggtgt ttcgacagca gcctatggca cattttcaga
    23281 tttcgaggaa gcaaaggcct atatcgaaaa gcatggtgcg cctatcgtag tcaaggcgga
    23341 tggcttggcg cttgggaagg gtgtcgtcgt ttctgagacg gttgagcaag cggtcgaagc
    23401 cgctcatgag atgcttttgg acaataaatt tggtgactca ggtgcgcgcg tggttattga
    23461 ggaattcctt gaaggagagg aattttcact ctttgccttt gttaatggtg ataagttcta
    23521 catcatgcca acggctcagg accacaaacg tgcctacgat ggcgacaaag ggcctaacac
    23581 gggtggtatg ggtgcctatg cgccagttcc acacttacca cagagtgtag ttgatacagc
    23641 ggttgacacc attgtcaagc cagttctaga agggatgatt aaagaaggtc gcccttatct
    23701 gggagttctt tacgcagggc ttatcctgac agctgatgga ccgaaagtca ttgagttcaa
    23761 cgctcggttc ggagatccag aaactcagat tatcttgcct cgcttgacct ctgactttgc
    23821 tcaaaatatc acagatatcc tggatagcaa ggagccaaat atcatgtgga cggacaaggg
    23881 tgtgactctg ggtgtggttg tcgcatccaa gggctacccg ctagactatg aaaggggcgt
    23941 tgagttgcca gccaagacag aaggcgatgt catcacctac tatgcagggg ctaagtttgc
    24001 ggaaaatagc agagcactgc tctcaaacgg cggacgagtt tatatgctcg ttaccacagc
    24061 agataccgtc aaagaagccc aagccagcat ctaccaagaa ctataccaac aaaaaataga
    24121 aggactcttc taccgaacag atatcggaag caaggcaatt aagtaaagat ataagaataa
    24181 cgcgccgtag tcgccaaaca cgataatggt cgtcgtggtg aaaagaccag aacagtgaat
    24241 gttctggtca gggggaaact tggagaccgt aggctcaaag tttaggaatg aaaccgaagg
    24301 tttgcttccg cctccatcac ctaagaccat tatcaaaaag aaaaataaaa attcacaaaa
    24361 tacgttaatg atcgtatggt ttgcgagcgt tagcgagcta atatagaaca atcaccgccg
    24421 ttgtgaaaga acgattggat gataatccaa tcgttcaggg aaattggaag accttgggtt
    24481 tccaatttag gcatgagaca cctttggtgg ctgctgccgt ccctcacaag ctaaggtgat
    24541 tgttgaaaaa gaggaaaaag gagaagaaat gaaaccagta atttccatca tcatgggctc
    24601 aaaatccgac tgggcaacca tgcaaaaaac agcagaagtc ctagaccgct tcggtgtagc
    24661 ctacgaaaag aaagttgttt ccgcacaccg tacaccagac ctcatgttca aacatgcaga
    24721 agaagcccgt agtcgtggca tcaagatcat catcgcaggt gctggtggcg cagcgcattt
    24781 gccaggcatg gtagctgcca aaacaaccct tccagtcatt ggtgtgccag tcaagtctcg
    24841 tgctcttagt ggagtggatt cactctattc tatcgttcag atgccgggtg gggtgcctgt
    24901 tgcgaccatg gctatcggtg aagctggagc gactaacgca gctctctttg ccctccgtct
    24961 cctctctgta gaagataagt ccattgcgga tgcacttgcc aactttgctg aagaacaagg
    25021 aaaaatcgca gaggagtcgt caaatgagct catctaaaac aatcggaatt atcggtggcg
    25081 gtcaactggg tcagatgatg gccatttctg ctatctacat gggccacaag gttatcgcgc
    25141 tggatcctgc ggcggattgc ccggcctctc gcgtggcgga aatcattgtg gcaccttata
    25201 acgatgtgga cgccctccgt cagttggcag accgttgcga tgtcctcact tatgagtttg
    25261 aaaatgtcga cgctgacggt ttggatgccg ttatcaagga tggacaactc cctcaaggaa
    25321 cagatctgct ccgcatttcg caaaatcgta tttttgaaaa ggactttttg tcaaacaagg
    25381 ctcaagtcac tgtggcaccc tacaaggtcg tgacttctag cctagacttg gcagatatcg
    25441 acttgtcgaa aaactatgtc ctcaagactg cgactggtgg ctacgatggt catggacaaa
    25501 aggttattcg ttcagaagca gacttggaag cagcctatgc gctagcagac tcagcagact
    25561 gcgtcttgga agaatttgtc aactttgacc ttgagatttc tgtcatcgtg tcaggaaatg
    25621 gcaaggaggt gacgtttttc ccagttcagg aaaatatcca ccgcaacaat atcctgtcta
    25681 agaccatcgt accagcccgc atttctgaaa gtctagtaga caaggctaaa gctatggcag
    25741 tgcgaatcgc agaacaactc aacttgtctg gaactctctg tgtggaaatg tttgcgactg
    25801 atgatgacgt tattgtcaat gaaatcgccc cacgaccaca taactctggg cactattcta
    25861 ttgaagcctg tgatttctct cagtttgaca cccatattct cggtgttctc ggagcaccat
    25921 taccagtcat caaactccat gcgccagccg ttatgcttaa tgtcctcggt cagcatgtcg
    25981 aggctgctga gcaatatgtg acagaaaatt caagcgccca cctccacatg tatggtaaaa
    26041 tagaagcgaa gcacaaccgc aagatgggac atgtgacctt gtttagtgat gtaccggata
    26101 gtgtggatga gcttggggaa gggattgatt tttaggacaa gtctatgata caaattatcg
    26161 ttaatacatt tattgaaaag gataagactg gagcagttgt tgaagtgttg tatgccagtg
    26221 ctgaccaaga taaggtaaaa gctaaatatg aagaactagc tgcacaatac cccgaaaatt
    26281 atttagctat ctatgatgta ccgctggata cggatttgaa tacactagat cattacccgt
    26341 ctgtgtttat tgaaaaagag gagtttgagt agaaatcttg gtttacctag atagcttatt
    26401 cccaacagct taagaagaaa ggaaaaatta acacatgatc aaccgttact ctcgccctga
    26461 gatggcgaat atttggagtg aagaaaataa ataccgtgct tggcttgagg tggaaatcct
    26521 ctctgacgag gcatgggctg agttggggga aatccctaag gaagatgtgg ctttgattcg
    26581 caagaaggcg gactttgaca tcgaccgtat tttggaaatt gagcaggaga cgcgccacga
    26641 tgtggtggct ttcacgcgtg cggtttctga gactcttggt gaagagcgca agtgggttca
    26701 ctatgggtta acttctaccg acgtggtgga tactgcttat ggttacctct acaagcaggc
    26761 caacgacatc atccgtcgtg accttgaaaa cttcactaat atcatcgctg acaaggccaa
    26821 ggagcacaag ttcaccatca tgatggggcg tactcatggt gtgcacgctg agccgacaac
    26881 ctttggtctt aaattggcaa cttggtacag cgaaatgaaa cgcaatatcg agcgtttcga
    26941 gcatgcagct gctggtgtag aagctggtaa gatttctggt gcggttggga actttgccaa
    27001 tatcccacca tttgtagagg agtatgtctg cgataaactt ggcatccgtg cccaagaaat
    27061 ctctacacaa gtccttcctc gtgaccttca cgctgagtac tttgcggttc ttgccagcat
    27121 tgcgacttca atcgaacgta tggcgactga gattcgtggt ctacaaaaat ctgagcaacg
    27181 cgaagtagaa gagttctttg ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg
    27241 caacccaatc ggttctgaaa atatgactgg tctggcgcgt gtcattcgtg gtcacatgat
    27301 tacggcttat gaaaacgtcg ctctctggca cgaacgcgat atttctcact catcagctga
    27361 gcgtatcatc acaccagata cgaccatttt gattgactac atgctcaacc gttttggaaa
    27421 tatcgtcaag aacttgacag tcttcccaga aaatatgatc cgaaacatga actcgacttt
    27481 tggtcttatc tttagccaac gggctatgtt gacattgatt gaaaaaggca tgacccgtga
    27541 gcaagcctat gacttggtgc aaccaaaaac agcctactct tgggacaacc aagtagactt
    27601 taaaccactt cttgaggcag attcagaagt aacatcacgt ctcactcaag aagaaatcga
    27661 tgaaatcttc aacccagttt attacaccaa acgagtggat gatatctttg aacgtcttgg
    27721 actaggtgat taattaaaaa ataaacagcg agcttcaatc tcgctgttta ttttttatcg
    27781 aaaagactta gtcttctttt cttttagtga gtccataggc tgctagtgtg gacatgagtc
    27841 ctgcgactac tagtcctgca gaatcgtgag ttcctgtttc aggaagtttt ttctctgtta
    27901 ccacaggagc tggatcttga ggaagagctt tgctttcctc agcgggagca gttgatggag
    27961 ctggttggct tgggatttct agttttggtt tttcttcagc aatagcggct tgtccgtttt
    28021 catcgcctac atgtgttacc atagttccga cttcgactat ttgagtaacg gcttcctgtg
    28081 ctacgacact atttacaagt gttttcactt ccttaccatc ggcagaagtg ctcacagagt
    28141 agaagttgct acgatgtcca ttgacgccct tagtaatgac ttgtgttttt cctttgagta
    28201 agagtggatt ttcacgagtc actgtggtaa atggaatttc ttctttttgg atatccagtc
    28261 taggttttac ctcagtagtt ggtgcaagac cactttcatc acccttgtga gttacaggag
    28321 cgccaacttc aaccacttgg tttataactt ctttggttac ctggctatca aggactgttt
    28381 ctgttgtttt tccattttca gtgagtacag agatgtaatg agttcgttca cctttgactc
    28441 ctgctgtgat aatattttcc tgaccagctg ggaggttagg attttctttc ttgataactt
    28501 caaatggaat ttcttcagtt cttgtgatga gttctggtct ggtttcaaca ttggcagcca
    28561 cttcattttc atccaggctt cctgaatgag ttgcagctgg tttgaggcct tgaagagcgg
    28621 cttttaggtt ggctacaagt gtgtcaagct cagcttgttt attacggttg aggttgtaat
    28681 ttagagctgt tttagctgcg tcaagggcct caagactttc tttactatat ccttctaagt
    28741 ttgtaggaat tttagctaat tcttcgcgga gagcattata attagcacgg aagtagtctt
    28801 tgttgtggtc tgcaaaggca gtcatgagtt caaagatttc ctcttccttg tactcagcgc
    28861 ttggtctatc tgcccagatt gaaagcatac ttccgactgt tggaagatct acttcaggat
    28921 atttggtaga agctagttga ttgaatggtg tttttccagt attctcaata gctttcttga
    28981 ggaaaccacc accatcttct ggtttttgac caagaatgta gtaccagtca ccgttggtat
    29041 tcaagaattt atagcctttg cttgctaggt attgaggtga tgcgaggtta tatccccacc
    29101 agcctttaga ccagtaagaa atcaagacat ctttgtcaaa ctgaacatcg tccttgtctt
    29161 catagtagaa gccatcgttg aaggccattg gttgaagccc tctttctttg gccatagctg
    29221 cgagggtgtt ggcatattcg gcaaatttgc catagagttg ataccacttg aggtagtacc
    29281 agccttgggc actagtcgca tcgttggcgt attcgtcagt accaaagttg aaaatctttg
    29341 ttttacctgc aaagaagtcc atgtatttac cgatgagggc ttttacaaag ttcatcgctt
    29401 cttcgttttt caagtccata gttgtttttg aaactttatc aaagtgggct tgaggatttt
    29461 taatacctaa tttttccatg gcaaccagca tagcatccat gtgacctgga ctgttaatag
    29521 ctgggatgag accgatgtcc ttagatttag cgtattcaat tagctctgtt acttctgcct
    29581 gtgttagtgc agtaccgttt ggatcgtcgt agtaagcttt agttccttcg ataatagctt
    29641 ttttaacgtc atcactagca taggtttttc cgttggcagt aatggtcata tcatcgagta
    29701 gaaagcgaag tccgtcattt cctagaagga gatggacatc agaatatccg agctcactgg
    29761 ccttgtctac gatgcgtttg agctggttca gagtaaagta tttgcgtcca gcatcgattg
    29821 agattacctt gtttttggca agtttttcaa cctcacgttt agcttcttct tcttttagag
    29881 cttcaggcgt gagggtcaag ttgttgacag tttcttgaag tttagcaatg gcttgatcaa
    29941 tcgtatcttg ttgggcacgg ctaaggttgc tatcgagaga gcgaatagct ttttcagctt
    30001 cttttacggc cgtgacgctt tctgcagtat aacggttcag gtcttttggt acctcgttaa
    30061 gtgcttgctc tgcagattca taatcagctg cgaagtattc agcgttggca tttgcaaaat
    30121 gacgcatgag tttgaagagg cgtgatggtg aataacgtgc agatggagtg tcagcccaag
    30181 cagctaccat accaccgatg attgggatat cagctccttc tgtttttggt acagaagtga
    30241 ttggtgtgtt tttaatacca ttgagcccct gatcgagatt gtaccagcct tggccatcag
    30301 cgtttcgtcc aagaacgtag taccaagcat cattggtatt aaggatttgg tgaccttttt
    30361 cagctagtag tttagaagaa gcgacatcgt agcctcccca accaccagtc cacatagaaa
    30421 cgatgatgtc tttgtcaaaa ctaccaaagc ttgtgtcgct attgtagtag ataccgtcgt
    30481 taaaagccat tggtttgaga ccgtgcgatt ttacaatacg agcgaggtca ttggcgtagg
    30541 caataaattt ttcatagcct tttacagggt agccttcgtt tggatagtat ttatcagctt
    30601 gaagcacact ccaaccttta gcatctgtcg catcattggc atattcatca agtccgatgt
    30661 tgaagatttc agtctttttc gcgaaataag cagcatactt gtcgataagg gcttttgtaa
    30721 aagcgacagc ttgttcgttg tcaagatcga cagtacgggc tgatttcttc ccaaaatagc
    30781 taaagttagg gttttggatt cccaattctt tcatggcatt gagaatcgca tccatgtgtc
    30841 caggactatt tactgtcgga atgagaccga tacctttatc tttggcatag ttaatcagat
    30901 ctgtcatttg actttctgtt aagtgattgc cgtttggatc gttgtaataa tcatttgtac
    30961 ctttttcaat ggcgcgtttg acatcgtcac tggcataggt cttgccgtta gctgtgatgc
    31021 tcatatcgtc caacatgaaa cggagtccat catttccgac taataggtgt aaatcagtgt
    31081 agccataatg tttcgcttta tcgatgattt ccttgagttg ttctggtgag aaatatttac
    31141 gtccagcatc aatagaaaca attttctttt tcgctagttt ttcatttaca gttgcagcac
    31201 gttcctttcc tgcctctgtt tccggtttgt cagcctctgc tttcgcttca tcttttttag
    31261 ctggtttatc cttgtcagtc ttgtctgtat ttgactcttt agaatcaacc tctttcgctt
    31321 cttccttttt agggctagct tcttctgcct ttttattagc agtttctttt tcagcagaag
    31381 ttggagttac cacttctgct ttatcactag gagttgaact aacttcctct tgtggttttt
    31441 cttctgtttt tggaagacta gctaccttat cagtagctgg agtttctgtt tctacagttt
    31501 ttggagcttc tggttgaagc actgctttag gtgtttcctc agtccgattt tcggatgatt
    31561 gaggggaatc agaaaccgta tggatggtcg gttggttttc tgtagtagta ggagtaactc
    31621 catcggctgc aacagtctgt gcttggaagg caaatccaat tagaacagaa gctgctccta
    31681 cagcgtattt acgaatagaa aaacgctgtt gtttttcatg tttcattgca aaacctcctg
    31741 attgcattgt tatattgata gcgattatat aaatcaacgc ctttatttta tttcttatat
    31801 taacgagagt caagaggaga tgacaaaaaa ctataataag tataaaaaaa tataaaattt
    31861 aaacttaaga tttcagattg gtcggaaaaa atacgtatat atatctagta taatttttgg
    31921 ttctatttct ataaaatatt ccacaaatta tagaattttc caaaaatagg taagcgctac
    31981 ctttttggtg tggtataata agcatagaaa aagcccaagc gattagctca ggctttcttc
    32041 ttagtgatca cggtcacatg agataaattt aatcttgtag taatcagatc gtttgtaagt
    32101 ttcactgtat tctaaaactt ggccagttga ttcgagtttg gtgattttag tttgtaggac
    32161 agtagggaat tgttcatcga ctccgaggac tgaagccgca tgttctggag ttggaaagac
    32221 tatttcgttg atttcttcaa agtgttcatc attcatgtga atgtggtagt ctaacttgaa
    32281 acgattatag atagaactat agtattcaag gtttggataa tttgcgttga tatattgttc
    32341 tgggatgtag gatgtatggt agatataaac gacaccgttt gattcgcgga tacgttcaat
    32401 cttgtagtag aattgatcgc cacgtagacc caatttttcc aagtaaacaa gcttgtttcc
    32461 gcgttcaatt gaaagaacag ttaccttatc atctttagca ttgaagagtt caatatctga
    32521 aaactctaca agcttgtgtt tgcgtgcacg tgaaacgaag gttccttttc cttgttggcg
    32581 gacaatatag ccatctttgg caaggtcgtt taaggcgcga acaactgtga tagagctgac
    32641 atcgtacatt gaaatgagtt ctgcttcagt gtaaaattta tctccactgc taaactgccc
    32701 agagatgatt ttatttttta attcgtcttt tatgtattga tatttgggaa ttgccatatt
    32761 tttacctcta ttttccttct ccatagaaaa ttttaccata aaagcgaaaa aaatagtagt
    32821 cttttgaata aaaaattaga ataatagtct gaaaaattaa gcgatatagg gattgctcat
    32881 attttatcaa tgtattctat acaaaattat tttaggtcct atattccgaa tttaaagagc
    32941 gtttgaaatg ggtctaaaaa tgtttgaaac taattgaatg tgtgtataat agtaaaaatg
    33001 cagtaaatat cccgacaatt tctattgaca attcaaacag attggtttat aattaatata
    33061 acaacaaatg aaagcgcaaa ctttcgcggt cggaaggtag ttttatgaca cgatttgaga
    33121 tacgagatga tttctatctc gatggaaaat catttaagat tttatctggt gccattcatt
    33181 attttagggt tcctccagag gattggtatc attcgctcta taacttgaag gctcttggtt
    33241 ttaatacggt agagacttat gttgcttgga atttacacga gcctcgtgaa ggtgagtttc
    33301 attttgaagg tgatctggat ttagagaaat ttctccaaat agcgcaggat ttgggtctct
    33361 acgcaattgt gcgtccgtct ccatttatct gtgcggaatg ggaattcggt ggcttaccag
    33421 cttggctctt gaccaagaac atgcgaattc gctcatccga cccagcatat atcgaggcag
    33481 ttggtcgcta ctatgatcag ttattgccaa gactggtgcc tcgtttgttg gacaatggtg
    33541 gcaatattct catgatgcag gttgaaaatg agtatggttc ttacggagaa gataaggctt
    33601 acctgagagc gattcgacag ctaatggaag agtgtggcgt aacctgtccc ctctttacat
    33661 cagatggtcc atggcgagct actctgaaag ctggaacctt aattgaagag gacctctttg
    33721 taacaggaaa ctttggttct aaggcacctt acaacttttc gcagatgcag gaattctttg
    33781 atgaacatgg taagaaatgg ccactcatgt gtatggagtt ctgggatggt tggttcaatc
    33841 gctggaaaga accgattatc acacgggatc ctaaggaatt ggcagatgca gttcgagagg
    33901 ttttggaaca aggctctatc aatctttaca tgttccacgg tggtacaaac tttggtttca
    33961 tgaatggttg ctcagctcga ggaactttgg acctgccaca agttacgtct tatgattacg
    34021 atgcccttct ggatgaagaa ggaaatccaa ctgctaaata tcttgcagtc aagaagatga
    34081 tggcaacaca tttttcagag tatccgcagt tggaaccact ctacaaagag agtatggagt
    34141 tggatgctat tccactagtt gaaaaagttt ctttgtttga aaccttagat agcttgtcaa
    34201 gtcctgtaga aagtctctat cctcaaaaga tggaggagct gggacaaagt tatggctacc
    34261 tactttatcg aacagaaaca aactgggatg cagaagaaga aagacttcgt atcattgatg
    34321 gtcgagatag ggcccagctg tatgtcgatg gtcagtgggt taaaactcaa tatcagacag
    34381 agattgggga atatattttt tatcaaggta aaaagaaagg gctatctagg ttagatatct
    34441 tgatagaaaa tatggggcgt gtcaactatg ggcataagtt cttagcggat acgcaacgta
    34501 agggaattcg gacaggggtc tgtaaggatc tgcatttctt actaaactgg aaacactatc
    34561 cactcccact agacaatcct gagaaaattg atttttcaaa aggatggact caaggacaac
    34621 cagcctttta cgcttatgac tttacagtcg aagagccaaa agatacttac ctagacttgt
    34681 ctgagtttgg taagggggtt gcctttgtca atgggcagaa tctaggacgt ttttggaacg
    34741 ttggcccaac tctctcactt tatatccctc atagctatct caaggaaggt gccaaccgca
    34801 tcattatctt tgaaacagaa ggtcaatata aagaagagat tcatttaact cgtaaaccta
    34861 cactaaaaca tataaagggg gaaaacttat gacaattgta ggatgccgta ttgatggacg
    34921 tttgatccac ggacaagtag ccaatctttg ggctggaaaa ctaaatgttt cacgcattat
    34981 ggttgtagac gacgaagttg tcaacaacga tattgaaaag agtggtttga aacttgcgac
    35041 accaccaggt gtgaaattga gtattttgcc agttgagaaa gctgcagcca atattcttgc
    35101 tggcaaatac gatagccaac gtctctttat cgtggctcgt aaaccagacc gcttccttgg
    35161 tttggtagaa gcaggtgtac cacttgaaac ccttaatgtt gggaatatgt ctcaaacacc
    35221 agaaactcgt tctattacac gttctatcaa cgtagtagac aaggatgtgg aagacttcca
    35281 caaactggca gaaaaaggtg ttaaacttac tgctcagatg gttccaaatg atccaatttc
    35341 agactttttg agcttattaa aataggaaaa aaatttttag gaggtcattg ttatgataca
    35401 atggtggcaa attttacttc tcactttgta ctcagcttat caaatctgtg atgagttgac
    35461 gatcgtttca tctgcaggtt cccctgtatt tgctggtttc attactggtt taatcatggg
    35521 agatgtgact actggtttac ttatcggtgg taacttgcaa ctgttcgttc ttggggttgg
    35581 taccttcggt ggtgcttctc gtatcgacgc aacttctggt gcggttcttg cgacagcctt
    35641 ctctgtttca caaggaattg atgcaccgct tgccattact acaatcgctg taccagtagc
    35701 agctctcttg acttacttcg acgttcttgg tcgtatgact actaccttct tcgctcaccg
    35761 tgtggatgct gcaatcgaac gctttgacta taaaggtatt gaacgcaact acttgcttgg
    35821 tgcgattccg tgggctctat ctcgtgccct tccagtcttc tttgcccttg cttttggtgg
    35881 tgcctttgta caatcagtag tagacttcgt tgaagcctac aaatgggttg cagatggctt
    35941 gacacttgca ggacgtatgc ttccaggtct tggatttgca atcttgcttc gttaccttcc
    36001 agttaaacgt aaccttcact accttgctat gggatttggt ttgacagcta tgttgactgt
    36061 tctttactca tatgtaacag gtcttggtgg cgctgttgct ggtatcgtag gtactcttcc
    36121 tgctgaagtt gctgaaaaaa ttggtttcgt gaacaacttc aaaggtttgt ctatgattgg
    36181 tatttctatc gtaggtattt tccttgcagt gcttcacttc aaaaatagcc aaaaagtagc
    36241 tgtagcagca ccttctacac catcagaaag tggggaaatc gaagatgacg aattctaatt
    36301 acaaacttac aaaagaagat tttaatcaaa tcaacaaacg tagcttgttt actttccaat
    36361 taggttggaa ctacgaacgt atgcaagctt ctggttacct ttacatgatc ttgcctcagt
    36421 tgcgtaaaat gtatggtgat ggaactcctg aattgaaaga aatgatgaaa gttcatactc
    36481 aattcttcaa tacttcacca ttcttccata ccattatcgc tggttttgac cttgccatgg
    36541 aagaaaaaga tggtgtaggt tcaaaagacg ccgttaacgg tatcaagaca ggtttgatgg
    36601 gaccattcgc tcctcttggg gatacaatct ttggttcact tgtacctgct atcatggggt
    36661 cagtcgcagc aactatggct atcgctggcc aaccttgggg gatcttcctt tggattgcag
    36721 ttgcagtagc gtatgacatc ttccgttgga aacagttgga atttgcttac aaagaagggg
    36781 ttaaccttat caacaacatg caaagtacct tgacagcttt gattgacgct gcatctgtac
    36841 ttggtgtctt catgatgggt gctcttgtag caacagtgat taactttgaa atttcttaca
    36901 agttgccaat cggtgaaaag atgattgatt tccaagacat cttgaaccaa atcttcccac
    36961 gtttgcttcc agcaatcttt actgccttta tcttctggtt gcttggtaag aaaggtatga
    37021 actctactaa agctatcggt attattatcg tacttgcttt ggctctttct gcccttggtc
    37081 actttgcact tggaatgtaa ttccttatga ctaaatcatt aattttggtg agccatggtc
    37141 gcttctgtga ggagcttaga ggtagcacag aaatgattat gggcccacaa gacaacattt
    37201 acacagtagc tcttcttcca gaagatggcc cagaagaatt tactgctaaa tttgaagctg
    37261 ttattgaagg attggatgat ttcctagtct ttgcggatct tctcggtggg acaccttgta
    37321 atgtggtgag tcgcttgatc atggaaggtc gtgatattga cctttacgca gggatgaatc
    37381 ttccaatggt gattgaattt atcaatgcga gccttacagg cgcagatgcg gactacaaga
    37441 gccgtgctgc agaaagcatt gtgaaagtta atgacctgtt agcgggcttc gatgatgacg
    37501 aagatgaata atactcttcg aaaatctctt caaactacgt caacgtcgcc ttgccgtagg
    37561 tatatgttac tgacttcgtc agtcttatcc ggcaacctca aaacggtgtt ttgagctgac
    37621 ttcgtcagtc ttatccggca acctcaaagc agtgctttga gcagcctgcg gctagtttcc
    37681 tacagatttt agttggaact cgattcaatt catgtgacaa cgtgaaaatc gttagagcat
    37741 tttatataga atatacatgg gaatgtagct tactcccatt cccatattta atagaaaaag
    37801 aggaactcaa tgctacatta tacaaaagaa gacttgctcg aattgggtgc agaaatcact
    37861 acgcgtgaaa tctaccaaca gcctgatgta tggagagaag cttttgaatt ttatcaagca
    37921 aaacgtgaag aaattgcagc cttcctacaa gaaatcgctg ataaacatga ctatattaag
    37981 gttatcttga caggtgctgg gacttctgct tatgtgggag ataccttgct accttatttt
    38041 aaggaagtct atgacgaacg caaatggaat ttcaatgcta ttgcgacaac agatatcgtt
    38101 gccaatccag caacctattt gaaaaaagat gtggcaactg tccttgtgtc ttttgctcgt
    38161 agtgggaatt cgcctgaaag tttggcgact gttgatttgg ccaaatcctt ggtggatgag
    38221 ctttatcaag tgacgattac ttgtgcagca gatggtaaat tggctcttca agctcacggt
    38281 gatgatcgta atctcttgct cttgcaacca gctgtctcta atgatgctgg atttgccatg
    38341 acttctagct ttacgtctat gatgttgaca actctcttgg tctttgatcc tacagaattt
    38401 gctgttaagt ctgaacgttt tgaagttgta tctagtcttg cccgtaaagt tttagacaag
    38461 gcagaagatg tcaaagagct cgttgattta gactttaacc gtgtcatcta tctaggcgct
    38521 ggtcctttct ttggacttgc tcatgaagct cagctcaaga ttttggaatt aactgctggt
    38581 caagttgcga ccatgtatga aagcccagtt ggcttccgtc acggtccaaa atctcttatc
    38641 aacgacaata cagttgtttt ggtctttggt acaacgacag actacactcg taagtacgac
    38701 ttggacttgg ttcgtgaagt tgctggtgac cagattgctc gtcgtgttgt gcttttgagt
    38761 gatcaagctt ttggtcttga aaatgtcaaa gaagtggccc ttggttgtgg cggtgtcttg
    38821 aatgatattt accgtgtctt cccttacatc gtttatgccc aactctttgc tttattgact
    38881 tcactcaagg tagaaaataa accagataca ccgtctccta caggtacagt aaaccgtgta
    38941 gtacaaggtg tcataattca cgaatatcaa aagtaagaca gtgtttatga attcttgaca
    39001 agaggatttg taaattatca gataaaccat agattgtcag tacgctttct atggtttgtt
    39061 tgcttgagag aaatagtaaa aggagaacag aatgaaagca tacacagagc gtgtatttgg
    39121 aaatgttgag ggtgaggatg tcttggccta tcgatttgag acagacggtg gctaccaact
    39181 tgaggttatg acttatggtg cgactatctt gcgctatgtc gcacctgaca aggctggaaa
    39241 ttttgccaat gttatcttgg gatttgatga ctttgatagt tatgtaggca atagtcccaa
    39301 gcatggagca agtgtaggtc ctgtagcggg tcgtattgca ggtgcgacct ttgagctcaa
    39361 tggtaagacc tatgaccttg aggttaataa tgctagcaac tgtaatcaca gtggttcaac
    39421 tggttgggat tccagcttgt ttgaagttga agaagtaagc gatcatggct tgactctcta
    39481 cacagagcgt acagatggga caggagggtt ccctggaaat ctcaagattt ggatcagtta
    39541 tcacttggaa gaaactggtg cctatgaaat cagctacaag gtaacgaccg atcaggatac
    39601 gctggtcaat ccaaccaacc acagctattt caacttgtct ggtgatttca cgcagacgat
    39661 tgaccgtcat gtcttccaac taaacacaga gggcatttac tcaatcgctc ctgacggtgt
    39721 tcctgccaaa actccagaag ccaaccgtga tgtggtcaaa cacgtctaca atggtacctt
    39781 gttgaaggat atctttgcag aagaagatga gcaaatccag ctggcatcag gtttggatca
    39841 tccatttgcc cttcctgcag gccatgacaa tgctggattc ctttatgacc aaaattcagg
    39901 tcgcttcctg cttttcaaga cagaagctcc ttgctttgtg gtctacacag caaactttgt
    39961 ggatgaaagt gtcatcatag gaggtcagcc aatgctacag cacaatggga ttgctcttga
    40021 agcgcaagct ttaccagatg ccattcacag tgaccttaaa ggccaagtca ttcttaaagc
    40081 tggtcaaacc ttcaccagta agacacgtta tgaacttgtt gtgaagtaaa agagtcattg
    40141 cgcctacttt tgggagctag gaataggtac gcagagacaa atagtaggaa aatatgatat
    40201 aactaagcgt tgaaagctat ctgttaatat aatattcaaa ctacaataag gagtaagaaa
    40261 gaaacgaaga aaattgtatt tgctagtgcc ttggctttga ccttggctgg agcagttttg
    40321 acaaatgatg tttttgcgaa cgacagactt gtggcaacac aaactactga tggtaaaaat
    40381 gaaaatgtat tgacctcaga ggtgctaaaa ccttctagtg gcaatgtttt ggttggaatc
    40441 aaaggagaat ttgtggctcc tcatcaacaa tctattttgg atgccatcaa tgctatctgt
    40501 aaagaagcgg ctgacgaagg tttggtagat aagtatgtcc ctatcaaatg gtcaactgac
    40561 ctagaaaagg cagcttttgc cagagctaca gaagcatcta taaccatgga tcatacccgt
    40621 ctttctagca aagatctttg gagtgccttt ccaacttcta atagtataat gggagaaaat
    40681 ttggcatgga atcatgacgg ttttctaaaa gctattgaac aatggcgtgc tgaaaaagca
    40741 gattatgtgg agaaaaaaat agtggttcag acaacgggaa atctggtcac tatgagtcgc
    40801 taattaaccc taaatttaca cacatgggga tggcagcttt taaaaatcct aacaatcaat
    40861 acaaagctat tacaattgct caaactctag gtgatgatgc ttcttcagag gaattggctg
    40921 gtagatatgg ttctgctgtt cagtgtacag aagtgactgc ctcaaacctt tcaacagtta
    40981 aaactaaagc tacggttgta gaaaaaccac tgaaagattt tagagcgtct acgtctgatc
    41041 agtctggttg ggtggaatct aatggtaaat ggtatttcta tgagtctggt gatgtgaaga
    41101 caggttgggt gaaaacagat ggtaaatggt actatttgaa tgacttaggt gtcatgcaga
    41161 ctggatttgt aaaattttct ggtagctggt attacttgag caattcaggt gctatgttta
    41221 caggctgggg aacagatggt agcagatggt tctactttga cggctcagga gctatgaaga
    41281 caggctggta caaggaaaat ggcacttggt attaccttga cgaagcaggt atcatgaaga
    41341 caggttggtt taaagtcgga ccacactggt actatgccta cggttcagga gctttggctg
    41401 tgagcacaac aacaccagat ggttaccgtg taaatggtaa tggtgaatgg gtaaactagg
    41461 ctcaggccat aggtaaagca ttcatcttac ttagcaaaaa gaatgaacga taagaaagag
    41521 gttgatggcg aacattggcc tcttttgatt tataaagatt ggattcttgt cgcctcaatt
    41581 tcagactttt ctattgtaag ctaatatttt atagcccatt aaaagcataa gcggtaatct
    41641 aatttaaaaa atgctgtaat tagtctgaag tccacactta cttgttgaga tgttatctct
    41701 gttttttatc gttataattt actgtatttt ttatagtatg cagaatattt ttaagtatat
    41761 ttcaatagaa atttcta
//
LOCUS       DAVMCG010000015        35987 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVMCG010000015 DAVMCG010000000
VERSION     DAVMCG010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.015"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            602..1294
                     /locus_tag="VYP66_000958"
                     /pseudo
     CDS             602..1294
                     /locus_tag="VYP66_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            1348..1737
                     /locus_tag="VYP66_000959"
     CDS             1348..1737
                     /locus_tag="VYP66_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1850525.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(2398..3426)
                     /gene="queA"
                     /locus_tag="VYP66_000960"
     CDS             complement(2398..3426)
                     /gene="queA"
                     /locus_tag="VYP66_000960"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1850526.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            3577..4284
                     /locus_tag="VYP66_000961"
     CDS             3577..4284
                     /locus_tag="VYP66_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1850527.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            4424..4600
                     /locus_tag="VYP66_000962"
     CDS             4424..4600
                     /locus_tag="VYP66_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1850528.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            4730..5665
                     /locus_tag="VYP66_000963"
     CDS             4730..5665
                     /locus_tag="VYP66_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1850529.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            5658..6446
                     /locus_tag="VYP66_000964"
     CDS             5658..6446
                     /locus_tag="VYP66_000964"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1850530.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            6447..6830
                     /locus_tag="VYP66_000965"
     CDS             6447..6830
                     /locus_tag="VYP66_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1850531.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            6846..7235
                     /locus_tag="VYP66_000966"
     CDS             6846..7235
                     /locus_tag="VYP66_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1850532.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            7319..8449
                     /locus_tag="VYP66_000967"
     CDS             7319..8449
                     /locus_tag="VYP66_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1850533.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLNAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            8454..9191
                     /locus_tag="VYP66_000968"
     CDS             8454..9191
                     /locus_tag="VYP66_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1850534.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            9202..9975
                     /locus_tag="VYP66_000969"
     CDS             9202..9975
                     /locus_tag="VYP66_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1850535.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEYKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            9965..10582
                     /locus_tag="VYP66_000970"
     CDS             9965..10582
                     /locus_tag="VYP66_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1850536.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            10792..11193
                     /locus_tag="VYP66_000971"
     CDS             10792..11193
                     /locus_tag="VYP66_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1850537.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            11193..11471
                     /locus_tag="VYP66_000972"
     CDS             11193..11471
                     /locus_tag="VYP66_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1850538.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            11461..12234
                     /locus_tag="VYP66_000973"
     CDS             11461..12234
                     /locus_tag="VYP66_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1850539.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            12235..13539
                     /locus_tag="VYP66_000974"
     CDS             12235..13539
                     /locus_tag="VYP66_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1850540.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            14113..14991
                     /gene="pstS"
                     /locus_tag="VYP66_000975"
     CDS             14113..14991
                     /gene="pstS"
                     /locus_tag="VYP66_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1850541.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            14991..15908
                     /gene="pstC"
                     /locus_tag="VYP66_000976"
     CDS             14991..15908
                     /gene="pstC"
                     /locus_tag="VYP66_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1850542.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            15898..16782
                     /gene="pstA"
                     /locus_tag="VYP66_000977"
     CDS             15898..16782
                     /gene="pstA"
                     /locus_tag="VYP66_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1850543.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            16793..17596
                     /gene="pstB"
                     /locus_tag="VYP66_000978"
     CDS             16793..17596
                     /gene="pstB"
                     /locus_tag="VYP66_000978"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1850544.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            17609..18367
                     /gene="pstB"
                     /locus_tag="VYP66_000979"
     CDS             17609..18367
                     /gene="pstB"
                     /locus_tag="VYP66_000979"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1850545.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            18379..19032
                     /gene="phoU"
                     /locus_tag="VYP66_000980"
     CDS             18379..19032
                     /gene="phoU"
                     /locus_tag="VYP66_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1850546.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            19189..20004
                     /locus_tag="VYP66_000981"
     CDS             19189..20004
                     /locus_tag="VYP66_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1850547.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(20024..21295)
                     /locus_tag="VYP66_000982"
     CDS             complement(20024..21295)
                     /locus_tag="VYP66_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1850548.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            21437..22168
                     /gene="budA"
                     /locus_tag="VYP66_000983"
     CDS             21437..22168
                     /gene="budA"
                     /locus_tag="VYP66_000983"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1850549.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            22178..22369
                     /locus_tag="VYP66_000984"
     CDS             22178..22369
                     /locus_tag="VYP66_000984"
                     /inference="COORDINATES: protein motif:HMM:NF021592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1850550.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKRR"
     gene            22404..22931
                     /locus_tag="VYP66_000985"
     CDS             22404..22931
                     /locus_tag="VYP66_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1850551.1"
                     /translation="MIYGLAMAAFFEETARLVFFKWLEKKRSLEKADALAYGLGHGGL
                     ELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQSLSVWQIYLLGFERILAL
                     GFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLSQVGWLTNPVLVEVILALEL
                     VLVAYGTKEIFCKKS"
     gene            23043..23993
                     /gene="murB"
                     /locus_tag="VYP66_000986"
     CDS             23043..23993
                     /gene="murB"
                     /locus_tag="VYP66_000986"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1850552.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            24052..25209
                     /locus_tag="VYP66_000987"
     CDS             24052..25209
                     /locus_tag="VYP66_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850553.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            25190..25996
                     /locus_tag="VYP66_000988"
     CDS             25190..25996
                     /locus_tag="VYP66_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850554.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            25993..26766
                     /locus_tag="VYP66_000989"
     CDS             25993..26766
                     /locus_tag="VYP66_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850555.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVSYYFISREKEEQA"
     gene            26763..27833
                     /locus_tag="VYP66_000990"
     CDS             26763..27833
                     /locus_tag="VYP66_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1850556.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            28078..28317
                     /locus_tag="VYP66_000991"
     CDS             28078..28317
                     /locus_tag="VYP66_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850557.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            28592..29077
                     /locus_tag="VYP66_000992"
     CDS             28592..29077
                     /locus_tag="VYP66_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1850558.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEILESQS
                     H"
     gene            29099..31717
                     /gene="alaS"
                     /locus_tag="VYP66_000993"
     CDS             29099..31717
                     /gene="alaS"
                     /locus_tag="VYP66_000993"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1850559.1"
                     /translation="MKQLSSAQVRQMWLDFWSTKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31807..33261)
                     /locus_tag="VYP66_000994"
     CDS             complement(31807..33261)
                     /locus_tag="VYP66_000994"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1850560.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            33440..34189
                     /locus_tag="VYP66_000995"
     CDS             33440..34189
                     /locus_tag="VYP66_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850561.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDHPDQSLESIYLSLAGRKEEVADASQGH"
     gene            34170..35804
                     /locus_tag="VYP66_000996"
     CDS             34170..35804
                     /locus_tag="VYP66_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850562.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVIAFSTSLTAFYNVFYESK
                     DLVSYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFVFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIALTVFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVITVLFTSAFLPYL
                     MMISLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENLDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLSILSMIYLLVVWIIASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
BASE COUNT        10250 a         6797 c         8178 g        10762 t
ORIGIN      
        1 ctagttcctt ctttaatctg gtttagtatt agttaaaaaa tcgctttaag cttgtaacta
       61 agagggagct aatcgactag attctccagc cgaacaggtg gtaatgtact ttttatagtg
      121 taatcctagc tgttgttaaa tttaaaatag aatcctctat cgagttaggg aattaaattc
      181 aaccaatttt atttatgttt tttctatcaa attatctaat attaaaatag tctcattctg
      241 atgagaaaac tattctattt atactgcatc gttgtgtaag gaatgatgaa agatgagtga
      301 aaattatcaa gttggaatgt ttgtatctaa atatattagc atgtatttag atcagatgtc
      361 tgcaatcctt tatatatgag attgattacg atatagttaa agtgttagtt caatagtaaa
      421 tatatcattc taagtctatt ttatatataa agtatattgt ttaacgtttg atagaaaaga
      481 tgctatacta gaagtaggat gtaatggcaa aatctaatac taataagcgc tatgcaatac
      541 gtaaactcgg aaagattttt ggttctgcgg taatcgggct aactttattt ttaggaggaa
      601 tctgaataca agttttgctc atgctgctga tgggattcaa tatgtcagag atgatactag
      661 agataaagaa gagggaatag agtatgatga cgctgacaat ggggatatta ttgtaaaagt
      721 agcgactaaa cctaaggtag taaccaagaa aatttcaagt acgcgaattc gttttgaaaa
      781 agatgaaaca aaataccgta gtgaaaatcc tgttacaatt gacggagagg atggctatgt
      841 aaccacgaca aggacctacg atgttaatct agagactggt catgttaccg aacaggttac
      901 tgttgataga aaagaagcca cggatacagt tatcaaagtt ccagctgaaa gcaaggttga
      961 agaagttctt gttccatgtg ctactaaata tgaagcagac aatgaccttt ctgcaggaca
     1021 ggagcaagag attactctag gaaagaatgg gaaaacagtt acaacgataa cttataatgt
     1081 agatggaaag agtggacaag taactgagag tactttaagt caaaaaaaag actctcaaac
     1141 aagagttgtt aaaaaatgaa ccaagcccca agttcttgtc caagaaattc caatcgaaac
     1201 agaatatctc gatggcccaa ctcttgataa aagtcaagaa gtagaagaag taggagaaat
     1261 tggtaaatta ctcttactac aatctatact gtagatgaac gtgatggaac aattgaagaa
     1321 actacttctc gtcaaattac taaagagatg gtaaaaagac gtataaggag agggacgaga
     1381 gaacctgaaa aagttgttgt tcctgagcaa tcatctattc cttcgtatcc tgtatctgtt
     1441 acatctaacc aaggaacaga tgtagcagta gaaccagcta aagcagttgc tccaacaaca
     1501 gactggaaac aagaaaatgg tatgtggtat ttttataata ctgatggttc catggcaaca
     1561 ggttgggtac aagttaatgg ttcatggtac tacctcaaca gcaacggttc tatgaaagtc
     1621 aatcaatggt tccaagttgg tggtaaatgg tattatgtaa atgcatcggg tgagttagca
     1681 gtcaatacaa gtatagatgg ctatagagtc aatgataatg gtgaatgggt gcgttaacag
     1741 attcctccct gcgacaaaat tgataatagt atgtctgaat atataattat atataaaaag
     1801 ctatagataa ggtcatctta tagcgactat aaaaaagtga acaagcctag tcttctgtac
     1861 attagaattc agatttgttc actttttgtt taatactcaa tgaaaatcaa agagcaaact
     1921 agaaaactag tcgcaggttg ctcaaagtac tgctttgagg ttgtagatag aactgacgaa
     1981 gtcagtcaca tatataatcc aaggtgacgt tgacgcggtt tgaagagatt tttgaagagt
     2041 ataagtcttt gattttgaga ctaaggagag tcagggtcaa agtagtgaat gattctgaaa
     2101 taactcataa tagtctcttg agaggacaga taagagtaac aaatatggtg ctactcatgt
     2161 gtcttgcatt ttgatttaca aacagcgaag aaaatatagg aagctgaaat aaaatataga
     2221 tgaatcaatt tggagagtca acgcaatcta tggcaatatt ttcgaagcta gggggaagca
     2281 ttttaatttc aatgtactag gcgtcttcta cagctagcta gagtttcaat tgtagatgtt
     2341 ctttgaaata atatcttagc gatttattgg tattagaaga attagagaaa ttctttctca
     2401 ataaataaac atggcgtcac caaaactgaa gaagcggtag tgttcttgga tggcatggtg
     2461 gtaggcatct aagactaatt cacggcctgc aaaggcagaa accaacatga ccagagttga
     2521 ttttggcaga tggaagttgg ttgagaaggc atccacgacc ttccactcat acccaggttt
     2581 gataaagata ttggtccaac cagaatctgc ttggatttgc ccatcaaact tggaaccaat
     2641 agtttccaag gtgcggatag aagtggttcc gacagcgatg acgcgaccac cattttcttt
     2701 gacagagcga agggtggcag cagcttcctc agaaagttga tagaactctg agtgcatttc
     2761 gtgttcgtcc agattatcca cagaaacagg tctaaaggtt ccgagtccga catggagagt
     2821 cagatagact agatgaacac ccttagcttg gatttctgcc agcagttctt tggtgaagtg
     2881 aagaccagca gtcggtgctg cagcagagcc gctttccttg gcgtagacgg tttgataacg
     2941 ttcacggtca tctaattttt cgtggatata aggtggcaga ggcatttctc ccagactttc
     3001 caagacttct aggaaaattc cttggtattc aaagcggaca atgcgtcccc cgtgggtcaa
     3061 ttcttctgta acgacagcgc tgaggcggcc atcaccaaag ctgatacgag taccgacctt
     3121 gaggcgtttg gcaggtttag ccagaacttc ccactcgtct ccactagtgt tcttaaggag
     3181 gagaagttcc acatgacctc ctgtctccac tttttgacca tagaggcggg cagggagaac
     3241 tcgggtgtcg ttcatgacaa gggcatcacc aggttccagc atatcaataa tagagtggaa
     3301 atgtttatct tgcatttctc ctgtctcacg gttgacgatg aggagtttgg aggcatcacg
     3361 tttttcaagg ggcgtttggg caatcaattc ctctggcaag tggaaatcaa aatcagctgt
     3421 attcatatat ttgttcattc tttctaagtt ctaatcctat ccattataac acgtttcaag
     3481 tttggacgct ctttttttag aaattaaatc gttttcactt gacaaaaatt ggtctatacc
     3541 atataataaa tatagacaga aatggaggat gaaaagatga aagttattaa agttgaaaac
     3601 caagttcaag gtggaaaagt tgcttttgag attttgaagg aaaaattggc taatggagct
     3661 caaactctag gacttgcgac aggaagtagc ccacttgaat tttacaagga aattgttgag
     3721 agtgaccttg atttttcaaa tctaaccagt gtcaaccttg atgagtatgt gggccttgat
     3781 ggggacaatc cacagtctta tcgttacttc atgcaagaaa acttgttcaa ccaaaaacca
     3841 tttaaagaaa gtttcttgcc tcgtggtgtt aaggacaatg ctgaagctga agttgaacgc
     3901 tacaaccaaa ttttggctga ccatccagtt gacctccaaa tcttgggaat cggtcgcaat
     3961 gggcatatcg gctttaatga gcctggtact ccatttgaca gtcaaacgca tctagtagaa
     4021 cttgaccagt ctactatcga agccaatgca cgcttctttg ccaagattga agacgtccca
     4081 acccaagcta tttcaatggg gattaaaaac attttggatg ccaagtctat tattcttttt
     4141 gcttacggtg agtcgaaagc agaagccatt gccggaacag tatctggccc agtgactgag
     4201 aacctacctg caagtagcct ccaaaatcac cctgatgtaa ccatcatcgc agatgctgaa
     4261 gcgcttagct tactcgaaaa ataaaaaagc aatgttctat tgaacgcttt caactcttgt
     4321 ataaatggaa gaaaaaatca aaattaaacc gcatttttgc ttgacaatta ttccttttac
     4381 gtgtagaatg aaatagatct tgaacttgaa gggagtgaaa aaaatgtcta aaacagtagt
     4441 acgtaagaat gaatctcttg acgacgcact tcgccgtttc aaacgtgcgg ttactaaagc
     4501 tggtactctt caagaaacac gcaaacgtga attctatgaa aaaccttctg taaaacgtaa
     4561 acgtaaatca gaagtagctc gtaaacgtaa aaaattctaa ttgaaatgaa aggctagaga
     4621 aatctagtcc tttttctttt aaataaatac tccaaagcct gcaaaaatct gaaacttcct
     4681 cctacaattt gatataatag agagaagaac tcatttgaag gaggaaatga tgtcggtttt
     4741 agtaaaagaa gtgattgaaa agcttagact agacattgtc tatggtgaac cagaattgct
     4801 tgaaaaggaa atcaatacag cggatattac gcgacctggt cttgaaatga caggctattt
     4861 tgactactat acaccagagc ggattcaact tttggggatg aaggagtggt cttatctgat
     4921 cagcatgcct tccaacagcc gttatgaagt tttgaaaaaa atgtttctac ctgagacacc
     4981 agcagtcatt gttgcccgtg gtttggtggt tccagaggag atgttaaagg ctgctagaga
     5041 atgtaagatt gctattttaa ccagccgtgc agctaccagt cgtttatctg gagagttatc
     5101 tagctatctg gattctcgtt tggcagaacg taccagtgtg cacggtgtct tgatggatat
     5161 ttatgggatg ggcgtcttga ttcagggaga tagtggaatt ggtaagagcg agacaggtct
     5221 tgagcttgtc aaacgtggtc accgtttggt agccgatgac cgtgtcgata tctttgccaa
     5281 ggatgagatt actctctggg gtgaaccggc tgaaattttg aaacacttga ttgaaattcg
     5341 tggggttggt attatcgatg ttatgagtct ctacggtgcg agtgctgtca aggattcttc
     5401 acaggttcag cttgctgtct atttggaaaa ttacgatacg cataagacct ttgatcgtct
     5461 tggaaacaat gcagaggaac ttgaagtttc tggcgtagcc attcctcgta ttcgtattcc
     5521 agttaaaaca ggtcgtaata tctctgttgt gattgaggca gctgccatga attatcgtgc
     5581 caaggaaatg ggctttgatg ctacccgttt gttcgacgaa cgactgacaa gtctcatagc
     5641 tcgaaatgag gtgcaaaatg cttgatccaa ttgctattca actaggaccc ctagccattc
     5701 gttggtatgc cttatgtatt gtgacaggct tgattcttgc ggtttatttg accatgaaag
     5761 aagcacctag aaagaagatc ataccagacg atattttaga ttttatctta gtagcctttc
     5821 ccttggctat tttaggagct cgtctctact atgttatttt ccgatttgat tactatagtc
     5881 agaatttagg agagattttt gccatttgga atggtggttt ggccatttac ggtggtttga
     5941 taactggggc tcttgtgctc tatatctttg ctgaccgtaa actcatcaat acttgggatt
     6001 ttctagatat tgcggcgcct agcgttatga ttgctcaaag tttggggcgt tggggtaatt
     6061 tctttaacca agaagcttat ggtgcaacag tggataatct ggattatcta cctggcttta
     6121 tccgtgacca gatgtatatt gaggggagct accgtcaacc gactttcctt tatgagtctc
     6181 tatggaatct gcttggcttt gccttgattc tgatttttag acggaaatgg aagagtctca
     6241 gacgaggtca tatcacggcc ttttacttga tttggtatgg tttcggtcgt atggtcatcg
     6301 aaggtatgcg aacagatagt ctcatgttct tcggccttcg agtgtcccaa tggctgtcag
     6361 ttgtccttat cggtctcggt ataatgatcg ttatttatca aaatcgaaag aaggcccctt
     6421 actatattac agaggaggaa aactaaatgt tagaagttgc atatattctt gttgccctag
     6481 ctttaattgt ctttttggtc tatctgatca ttactgtaca aaagcttggt cgtgtcatcg
     6541 atgaaacaga aaagacgatt aaaaccttga cttcagatgt ggatgtgacc ttgcatcaca
     6601 ccaatgagtt gttggctaag gtcaatgtct tggcagatga tatcaatgtc aaggtggcta
     6661 cgattgatcc actcttcagt gctgttgcag atttatctct atctgtttca gacctcaatg
     6721 accatgcgcg tgtcttgagc aagaaagctt catcagctgg ttcaaaaaca ctcaagactg
     6781 gtgcaagtct gtcagctctt cgtcttgcaa gtaaattttt caaaaaataa aaaaggagaa
     6841 tccttatggg taaattatcc tcaatccttt taggaacggt ttcaggtgca gctcttgcct
     6901 tgtttttaac aagtgataag ggcaaacaag tttgcagtca ggctcaagat tttctagatg
     6961 atttgagaga agatccggag tatgccaagg agcaagtctg tgaaaaactg acagaagtta
     7021 aggagcaggc tacagatttt gttctgaaaa caaaagaaca ggttgagtca ggtgaaatca
     7081 ctgtggacag tatacttgct caagctaaat cctatgcttt tcaagcgaca gaagcatcaa
     7141 aaaatcaatt aaataatctc aaggaacaat ggcaagaaaa agccgaagct cttgatgact
     7201 cagaagagat tgtgattgat ataacagaag aataaaccat caccatctcc ggacggacta
     7261 tgtatctggg gatggtgatt tttatctgga atctagtctt tgtggtataa taattactat
     7321 gcagaaaaaa ccaacgtcag cctatgtgca catcccattt tgtacccaga tttgttatta
     7381 ttgtgatttt tcaaaggtct tcatcaaaaa tcagccagtc gacagctatt tagagcatct
     7441 gctggaagag tttcgttctt atgatattga aaagttgtca accctttata tcggtggtgg
     7501 aacaccgaca gccctgtcgg ctccgcaact ggaggtttta ctgaatggct tgactaaaaa
     7561 cttggacttg tctgtcttag aagagttgac cattgaagcc aatccaggcg atttgaatgc
     7621 ggataagata gctgttttga aaaattcggc tgtcaatcgt gtttcgctag gtgtccagac
     7681 ctttgatgat aagatgttga aaaagattgg gcgcagtcat ttggagaagg atatttatga
     7741 aaatatcgat cgcctgaaac tggctggttt tgacaacatc tccattgatt tgatttatgc
     7801 tctgcctggt cagaccatgg agcaagtaaa ggaaaatgtg gctaaagcca ttggactgga
     7861 tattccccac atgagtttgt atagtttgat tttagaaaac catacggtct ttatgaaccg
     7921 gatgcgacgt gggaaattgc ctctgcctaa ggaggaacta gaagcggaga tgtttgagta
     7981 catcattgca gagctggagc gagcgggttt tgagcattat gagatttcta atttctccaa
     8041 acccggcttt gaaagtcgtc ataatctcat gtactgggac aatgctgaat actatggtat
     8101 tggtgcaggg gcatctggtt atgtcaatgg agtacgttat aaaaatcatg gtcccattcg
     8161 tcattatctc agtgcggttg aggaaggcaa tgcttgtatt acagaagatc acctgagtca
     8221 aaaggagcaa atggaagaag aaatgttctt gggactccgc aagaaatccg gggtttccat
     8281 ggcgcgattt gaggaaaaat ttggacagtc ttttgctgga ctttatggag aaattgtcag
     8341 agatttggtt caacaaggcc tcatgcagat tgagggtgac cacgttcgca tgacaaagag
     8401 aggtctcttt ttgggagata ctgtagcaga acgatttatt ttggagtagg atcatgggct
     8461 taacttatca aatgaaaatg aaaattcctt ttgatatggc tgatatgaac ggtcatatca
     8521 aacttccaga tgtgattttg ctgtcactgc aagtttcagg gatgcaatcg attgaactgg
     8581 gagttagtga taaggccatt ttggaagact ataatctggt ctggattatc gcagaatatg
     8641 atattgaggt ggttcgtttg cctcgttttg cggaagaaat taccatcgaa acggaagcct
     8701 tgagctacaa tcgacttttt tgctaccgtc gctttactat ttataatgaa gcggggcagg
     8761 agctcatcca tatgatggcg acctttgttc tcatggaccg cgacagtcga aaagtccatg
     8821 ctgttgaacc tgagattgtg gctccttacc agtctgattt tgataaaaaa cttatccgtg
     8881 gaccgaagta tgaatccttg gaagagccga tcagcaagga ttaccatgtt cgtttttacg
     8941 acttggatat gaatggtcat gtcaataaca gtaaatactt ggactggatt tttgaggtca
     9001 tgggagcgga ttttttgacc cactatattc ccaagaaaat caacctcaag tatgtcaagg
     9061 aagttcgacc aggtggggtg attacatcgg ctgttgaacg gactggactg gaaagcaagc
     9121 atgaaattac aagtgatggg gttatcaatg cccaagcaat cattacttgg caagaaataa
     9181 aaaaggttta gggagaaata gatgaaatat aaaggctatt taattgattt agacggaacc
     9241 atttataagg ggaaagaccg aatccctgct ggagagactt ttgttcatga attgcaaaag
     9301 cgggacattc cctatctctt tgtaaccaac aatacaaccc gcactccaga gagtgttaag
     9361 gagatgttgg ctcagaattt taatatcgat acgcctctat cgactgtcta cacagcgact
     9421 ttggcaacca tcgactatat gaatgatttg gggcttgaaa agactgtcta tgtcgtcgga
     9481 gaagcaggac tcaaggaagc catcaaggcg gctggttatg tggaatacaa ggaaaaccct
     9541 gcctacgtgg tagttggtct ggattggcaa gtcgactatg aaaaatttgc cacagcaact
     9601 cttgctattc aaaagggtgc ccattttatc ggaaccaatc ctgacctcaa catcccgacg
     9661 gaacgtggtc ttttgccagg tgctggctca ctgattacgc tgcttgaagt agcgacacga
     9721 gtgaagccgg tttatatcgg aaaaccaaat gccatcatta tggacaaggc ggttgagcac
     9781 ttaggtttgg aacgtgaaga gttaatcatg gttggggaca attatttgac tgatatccgg
     9841 gctgggattg acaatggcat tccaacgctc ttggtgacga caggttttac taaggcagaa
     9901 gaagtagctg gcctgccaat cgcaccgaca catgtggttt ctagccttgc ggagtgggat
     9961 tttgatgaaa actaaattga ccttttgggg ctctatgctc tttctcctct ccctctcaat
    10021 ccttctgacc atttatctgg cttggatttt ctatcctatg gagattcagt ggctaaactt
    10081 aacgaatcga gtctatctaa aaccagaaac cattcaatac aattttcata tcttgatgaa
    10141 ttatctgacc aatcctttta gtcaggtctt acagatgcct gattttcgtt cgtcagcagc
    10201 tggtctgcac catttcgcag tggtcaagaa tctctttcat ttggttcagc tagtagctct
    10261 agtgacactg ccaagtttct atgtctttgt caataggatt gtgaaaaagg actttttgtc
    10321 tctttatcga aaaagtctcc tgactctagt agtcttacct gtgatgattg gacttggggg
    10381 agttttgatt ggttttgacc aattctttac tcttttccat caaattctct ttgtgggaga
    10441 tgatacctgg ctttttgatc cagccaagga tcctgttatt atgattttgc cagagacctt
    10501 ctttcttcat gccttcctcc tcttttttgc cctctatgaa agcttctttg ggtatctgtg
    10561 tctgaaaagt cgtaggaagt gaaatgaaag atgtttttaa tttgcatata taaaaatata
    10621 tatcgtttaa aaccatcgtt aagagtgaat taaccaaatc caattgtgtc aatcgttcgc
    10681 aaacagccta tttttcttga aaaaataggc tttttttcta aaaatcccta gtcaagcgct
    10741 ttattttttt gtataataga agtagcaaag tatagataag aagagaaaag catgattaca
    10801 ctatttctat caccgagctg tacatcatgt cgtaaggcta aggcctggtt agaaaaacat
    10861 aaggttccct ttgtggaaca caatattatg accagtcctt taacaagaaa agaattgcaa
    10921 cacatccttt ccttgaccga aaatggtact gatgacatca tttcaactcg ttcaaaaatt
    10981 tttcaaaaat tgaatattga tgtagagagt atttcggtat cggaattgct tcatttgatt
    11041 gagcagtatc ctagtctttt gcgtcgtcca attattattg atgccaagcg tatgcaaatc
    11101 ggttttaatg aagatgagat tcgtgctttt ctccctcgta gttatcgtaa gcaagaacta
    11161 aaagaagcaa gaatgagagc tggtattagt taatgaacaa acagtatagt tacccactag
    11221 atttgtcgtg gagcactgaa gaacttgctt cagtgctttc tttttttaat gatgttgaag
    11281 ctgcctatga aggcaaagta gaggctaaaa agttactgga ctcctataag ggattcaaag
    11341 cggtcgtgcc aagcaagagc gaagagaaac gtttgggacg agaatttgaa acggttagtg
    11401 gctattcact ttaccgagca gttcaggctg ccaaagaaaa aggggaagga aagatttctc
    11461 ttggaaagta aatttgaatt tgctaaagag cttgttaaga aagcaggcca gtacattctt
    11521 gaccatatgc aggaagactt gcgtgttgaa accaagtcct ctccaacaga tttggtgacc
    11581 agactggaca aagaagttca ggaactcttg gttggtgaga ttttgtcccg ttatcctgag
    11641 gataagattt gtgctgaaga aggttgtctg cgagcctcgg ttcaagaggg caaggtttgg
    11701 gtcattgatc ccattgatgg taccaataat tttgtagccc agcaggaaga ttttgctgtt
    11761 atgatggctt attttgaaaa tggtcaggga cagtttggtc tgatttatga tgtggtcaaa
    11821 ggggattgtt accacggtgg tggggaattt ccagtttgtc taaatgatag gcccctagct
    11881 ccttttaaaa ctaaaccact tggagatttt ctcattgcag ggaatagtgg tatgctggaa
    11941 accaatgaat gggggctggc tgatttgagc cgagcggttc ttggtgttcg tgtctatgga
    12001 agtgcggcca ttagttttgc caagattttg tcagggcgtt tgttgaccta tctcacttat
    12061 ctgcaaccat gggattatgc cgcagctagt attttagggg aaagtctggg ctatcgggtt
    12121 gtgacccttt ttggtgaagc tcctgatttt caaaccagac agcctgtcat gatggtgcct
    12181 cttgagatgc aggaggaaat tcagtcctat atttacgaaa ggaaaagaac ttaaatgcaa
    12241 tttccagaag gatttgttga aaaatataaa gaaatactag gagatgaggc aagagatttt
    12301 cttgcctctt ttgaggagga agcggtttcg gcctttcggg tcaatccctt aaaagaagag
    12361 caactttcct tttctgatgc cattactcaa accccttggg gccactatgg gaaggtttca
    12421 gggaaatcgc ctgagcatgc tacaggttta gtttattcgc aagaacctgc tgctcaaatg
    12481 gtggctcaag tagcccaacc cagtcctggt atgaaggtct tggacttggc tgctgcaccg
    12541 gggggcaaat caactcaact ggcagcctat ctagcagggg aggggctact tgtttccaat
    12601 gaaatttcaa gcaaacgggc taagattttg gttgaaaaca tggagcgttt tggagcgaca
    12661 aatgtcgtgg tgaccaatga atctgccgac cgcttggtca aggtctttaa aggctatttt
    12721 gacttaatcg ttcttgatgc cccttgctct ggtgaaggaa tgtttcgtaa gcaacctgat
    12781 gctatggact attggagctt agattatccg agtcaatgtg ctagcttgca aagagaaatt
    12841 ctggaggatg cagtgaccat gttagctgaa ggtggtcgtc tggtttattc gacctgtacc
    12901 tgggcacccg aggaaaacga agagattgtc aattggttgc tggaagagta tgattttgac
    12961 ttgttgccag tagagcatat caatggaatg gtagctggta ttgacctgcc agaaacggct
    13021 cggatgtacc ctcatcagtt taagggagag ggtcagtttg ttgcccatct acagtttaag
    13081 ggtaacaatc cagctcctaa atttaaggca agtaagagta acctcagccg tgaacaagtt
    13141 gccttgtggc aggaatttgc ccaaaaccat ttgaaggtca atctaccggg tatcttgcag
    13201 atttttggag accagcttta tctcttgcca gaacttttgc cagatttagg gaagctcaag
    13261 attgctcgca atggactgca tctgggtact tttaagaaga aacgctttga gcccagtttc
    13321 gctcttggtt tagccttgaa accgagtcag gtcgaacagt cggttgaaat tggccaagaa
    13381 gcgtttgtca agtatgcggc tggagaaacc gttcagctgg cagaaagtct gccaaatggt
    13441 tggtaccaag ttttggttaa aggcaatggc ttgggctttg caaaggttac tggaaatgtt
    13501 ttgaaaaatt attttccaaa aggcctcaga ttcaaatgaa aatgctagtc aaatatctta
    13561 ttctatgtta tagtgaaagt atggattttt ttagtaggat gattcttgat atcttgattg
    13621 ccatcacatg tagttttact actcgatgaa aatcaaagag caaactagga agctagccat
    13681 agatagctca aaacactgct ttgaagagat tttcaaagag tacaagaagt ttagttatta
    13741 gcgttcttac cgcttgtaaa ctagatttct cataaaatag aatcttttcc ttttagttgt
    13801 aaactagtct gggagagtag agaggtttga gatacctttc tagcttttgg attatcatct
    13861 aagaagagta atttcccttg cattaaaaag gggaaaaaga gacacgaaat gactataatg
    13921 ggtgacaatg ggggaaggga tagacaagag attttatcca catatgaaaa aaggaggtta
    13981 ggaaagagta atatagccta tattatataa ataatcaatt gcgcagaaat ttggtaagaa
    14041 ttcatgcgtc aactcataaa gaactactta aaaaattcac agtattcata attattttcg
    14101 aggagaaaaa cagtgaaaaa aagaaaaaag cttgctctgt ctcttatcgc tttttggctg
    14161 acggcttgtt tagtaggctg tgctagctgg attgatcgtg gagaatccat aacggctgtt
    14221 ggctcaactg ccttgcaacc cttggttgaa gtagcggcag atgaatttgg cacgatccat
    14281 gttggaaaaa cggtcaatgt ccaaggggga ggttctggta caggcttgtc ccaggttcag
    14341 tctggggcag ttgatatagg aaactcagat gtatttgctg aggaaaaaga cggaattgat
    14401 gcttctgctc ttgttgacca caaggtcgcg gtagctggct tggctctgat tgtcaataag
    14461 gaggttgatg ttgataacct aacgacagag caacttcgtc aaatcttcat aggtgaggta
    14521 accaattgga aagaggttgg tggtaaggac ttacccatct ctgttatcaa tcgggcagcc
    14581 ggctctggct ctcgtgctac ctttgatact gtcattatgg aaggtcagtc tgccatgcaa
    14641 agtcaggagc aggattcaaa tggagcggta aaatcaatcg tatcaaaaag tccaggagct
    14701 atctcttatt tatctcttac ctatatagat gattcggtca aaagcatgaa gttgaatggc
    14761 tatgacttaa gtccagaaaa tataagtagc aataattggc ccttgtggtc ttatgagcat
    14821 atgtatacat tggggcagcc caatgagttg gctgcagaat ttctcaattt tgttctctcg
    14881 gatgagaccc aagaagggat tgtcaaagga ttgaagtata ttccgattaa ggaaatgaag
    14941 gttgaaaaag atgctgccgg aactgtgaca gtgttggaag ggagacaata atgaatcaag
    15001 aagaattagc taagaaaatg ttgcttccat caaagaattc tcgtctggag aaattaggaa
    15061 aaggtttgac ctttgcctgt ctttctttga tagtcatcct tgtggccatg attttggttt
    15121 tcgtagcgca aaaaggcttg tcgaccttct ttgtcaatgg tgtgaatatc tttgactttc
    15181 ttttgggagg aacttggaat ccttctagta aagaatttgg tgcccttcct atgattttgg
    15241 gttcctttat cgttaccatt ctctcagccc ttatcgcaac accctttgct attggtgcag
    15301 cagtttttat gaccgaagta tcaccaaaag gggcgaagat tttgcaacca gctattgaac
    15361 tcctggttgg gattccttca gtagtgtacg gatttattgg cttgcaagtc gtcgttccct
    15421 ttgttcgcag tgtctttggt gggactggtt ttgggatttt gtcagggatt tccgtcctct
    15481 ttgtcatgat tttgccgacc gtaaccttta tgacaacgga tagcttgcgt gcggttcctc
    15541 gttattatcg tgaggctagt ttcgctatgg gagccactcg ctggcagact atctggcgtg
    15601 tgatcttgaa ggcggcccgt tctggtattt tcactgcagt ggtctttggg atggcgcgtg
    15661 cctttggtga ggctctagct atccagatgg ttgtcggaaa ctcagctgtt atcccaactt
    15721 ccttgaccac accagctgca actttaactt ctatattaac tatgggaatt gggaacactg
    15781 tcatgggaac tgtaaataat aatgttctct ggtcactggc cttggtactg ctcttgatga
    15841 gcttagtttt taacagtgtg attaaattga ttacgaaaga aagaggaaag aaaaattatg
    15901 cgcgctaaga aattagataa acttgcaaca gctgtcctct atacgattgc tagcatcatt
    15961 gtgacaatct tggcttcctt gattctctat atcttggttc ggggcttgcc ccatatctct
    16021 tggtctttct tgactggaag gtcttctgct tttcaagcag gtggtgggat tggcattcag
    16081 ctttacaatt cctttttcct attggtcatt accttgatta tttctgtacc tctttctatg
    16141 ggagctggga tttacttggc tgaatatgct aaaaaaggtc ctgttaccaa ctttgtgcga
    16201 acttgtattg aaatcttgtc ctctttacca tcagtggtgg tgggtctctt tggttacttg
    16261 atctttgtag tccagtttga gtatggattt tcaatcattt caggtgcttt ggccttgaca
    16321 gtctttaact tgcctcagat gacgcgtaat gtagaagata gtttgaaaca cgttcaccat
    16381 acccaacgtg aggctggtct ggctcttggg atttctcgct gggagacagt ggttcatgtt
    16441 gttattccag aagcgcttcc aggtattgta acgggtgtcg tcttggcatc tggtcgtatc
    16501 tttggcgaag ctgcagctct gatctataca gcagggcaat cggcgccagc tcttgactgg
    16561 tctaactgga atatcctcag tgtgactagc cccatctcta tcttccgtca agcagaaacc
    16621 ttggctgtcc atatctggaa agtcaatagt gaaggcacta ttccagatgg aaccattgta
    16681 tcagcaggtt ctgccgctgt gctcctgatc tttatcctga tttttaactt tggagctcgt
    16741 aagttcggaa gctatctaca caagaaatta accgctgcct aaaggagaag ccatgtcaac
    16801 atataactgg gatgagaagc atatccttac ctttcctgaa gaaaaagtag ccctttctac
    16861 taaggatgtc catgtttatt atggtaaaaa tgaatccatt aaggggattg atatgcaatt
    16921 tgaaagaaat aaaattacag ctttgattgg tccgtcggga tcggggaaat ctacctactt
    16981 acgcagtctc aatcgcatga atgataccat tgatattgct aaagtaactg ggcagattct
    17041 ctatcgtgga attgatgtca accgtccaga aatcaacgtt tatgaaatgc gtaaacacat
    17101 tggaatggtt tttcaacgcc ccaatccatt tgctaagtca atttaccgta atattacctt
    17161 tgcgcatgaa cgtgctggag ttaaggataa gcaagtccta gatgaaatcg tagaaacctc
    17221 ccttcgtcag gctgccctct gggatcaggt taaagacgat ctccacaagt cagccttgac
    17281 cttatcaggt ggtcagcaac aacgtctctg tatcgctcgt gccatctctg ttaagccaga
    17341 tatcctctta atggatgagc cagcctcagc cttggatccg attgcgacca tgcaactaga
    17401 agagaccatg tttgagctca agaaaaactt taccatcatc attgtaacgc ataatatgca
    17461 gcaggctgct cgtgcaagtg actatacagg cttcttttac ttgggtgatt tgattgagta
    17521 tgacaagact gcaactattt tccaaaatgc caagctacag tccaccaatg actatgtatc
    17581 tggtcacttt ggttagaaag gaaaccgtat gacagatgcg attttacagg tatcagacct
    17641 gtccgtttat tataataaaa agaaggcttt gaatagtgtt tccctatctt tccaacctaa
    17701 ggaaattaca gccttgattg gtccatctgg atcagggaag tcaaccctcc tcaagtctct
    17761 caaccgcatg ggagatctca atccagaggt gaccacaact ggatccgtgg tgtacaatgg
    17821 tcacaacatc tacagtccgc gtacagatac ggttgaatta cgtaaggaaa tcggaatggt
    17881 tttccaacaa cctaatcctt tccctatgac tatctatgag aatgttgtct acgggcttcg
    17941 tatcaatgga attaaggata agcaggttct ggatgaagcc gtagaaaaag ccttgcaagg
    18001 tgcctctatc tgggatgagg tcaaggatcg tctatatgat tcagctattg gattgtcagg
    18061 tggtcaacag cagcgtgtct gcgtggcccg tgtcttggca actagtccta aaatcatcct
    18121 cttggatgag ccaacttcgg ctttggatcc gatttcagct ggtaagattg aggaaacctt
    18181 gtatggtcta aaagacaagt acaccatgct tctggtaacc cgttccatgc agcaagcttc
    18241 acgtatctct gataagacag gatttttcct agatggagat ttgattgaat ttaatgatac
    18301 caagcagatg ttccttgatc cccaacacaa ggaaacggaa gactatatta caggaaaatt
    18361 tggataagga gatgaaagat gttacgatct caatttgaag aagatttaga gaaattacat
    18421 aaccagttct acgctatggg acaagaagtg ctctcacaaa tcaatcgtac ggtacgtgct
    18481 tttgtcacgc atgaccgtga cctggcaaaa gaggtcatag aagatgatgc agaagtaaat
    18541 gaatacgaag tgaaactgga aaagaaatca tttgaaatga tcgcactcca acaaccagtc
    18601 tctcaagatt tgcgtacagt cttgactgtc cttaaggctg tatcagatgt ggagcgtatg
    18661 ggggatcacg ctgtagccat tgcccaggca accatccgta tgaaggggga agagcgcatc
    18721 ccagctgtag aggaagaaat taaaaaaatg ggacgtgaag ttaaaagcgt tgttgaagca
    18781 gcacttgatc tttatcttaa tggttctgtt gacgacgcat accgggtggc ctccatggat
    18841 gagcaaatta accactattt tgaaactatc cgtgaccttg cgactgaaga gattaagaaa
    18901 aatccagaag ccattgttac gggtcgtgat tatttccaag ttatttccta cttggagcgt
    18961 atcggtgact atgctaaaaa tatctgtgaa tgggttgtct actttgaaac aggtaagatt
    19021 gtcgaactat aaaatagttt aattctgtat aaaaaggagc ttgaaatcaa ctgatggctc
    19081 ctttttttga acgaaaaaat atttttgaga taaaaattta aaaaacactt gacaagtaac
    19141 ttggatatcg ttataattat acaaaattaa cagagaggtt gtttatttat gaaatcaaaa
    19201 aaatggatat ttgttttatg taattttctt gcaagtttct tcttagtagc ttgccagtca
    19261 ggttctaatg gttctcagtc agctgttgag gccattaagc aaaaggggaa attagttgtg
    19321 gcaaccagtc ctgactatgc accctttgaa tttcaatcat tggttgacgg aaagaatcag
    19381 gtagtcggtg cagacatcga catggctcag gctatcgctg atgaacttgg ggttaagttg
    19441 gaaatctcaa gcatgagttt tgacaatgtt ttgaccagtc ttcaaactgg taaggctgac
    19501 ctagcagttg caggaattag tgctactgac gagagaaaag aagtctttga tttttcaatc
    19561 ccatactatg aaaacaagat tagtttcttg gttcgtaagg ctgatgtgga aaaatacaag
    19621 gatttaacta gcctagaaag tgctaatatt gcagcccaaa aagggactgt tccagaatca
    19681 atggtcaagg aacaattgcc aaaagctcaa ttaacttccc taactaatat gggtgaagca
    19741 gtcaatgaat tgcaggctgg aaaagtagat gctgttcata tggatgagcc tgttgcactt
    19801 agttatgctg ctaaaaacgc tggcttagct gtcgcaactg tcagcttgaa gatgaaggac
    19861 ggcgacgcca atgccgttgc tcttagaaaa aatagtgatg atttgaaaga agtggtagac
    19921 aaggtcatcc aaaaacttaa ggatgaagga acttaccaaa gctatcttga aaaagcagca
    19981 agtctaactg aagttgaaga ataagaaaaa gcagagttgg atgtcattcc aattctgctt
    20041 ttaaatagtt taaaacattt tccagattgt ctagggacac cttggcaaat tgataaggac
    20101 aggtgcttaa ataggcctct tcaaagaagt ccaagcccag ttgactgtgt ttgagactgg
    20161 cgattttagg atactgtctc aggtctagca ataaaccatc gtgtagggga taatgaggaa
    20221 ggggacaagg tgttttagtt atcctttcct cgatttgttt ttggtaagat tcatgattgg
    20281 tcaagcgagc caaacgattt ttttcaaaca attgactgtc aatatagagt gacagggcct
    20341 tttgcataat gaggttgctg tcgtagtcta ggatattttt gtaggccaca aatgcttctt
    20401 tgatagcatt tggaagaatg agtgctgtaa tacgaagggc aggaaaaagg ctggtcgaga
    20461 aggacttgat ataaatgaca cgctcctctg tatcaagata gtggaaggtt tggcccttct
    20521 tggagtccaa atcacccaga taatcgtcct ctacgatata gacatcatac ttggcagcta
    20581 agttaagaat agatcgtttg tcctgctcag aataggaatg tcccagagga tagtgaaatc
    20641 ggggaatggt gtagaaaaat ttaatttttc ctgttttgaa gtggccttcc agctcctcca
    20701 agtcaatccc atcaatgcct cgttcaatcg tttgatagtc cagcccctgt gcaatcaaga
    20761 ggcgattcat ccgatggtag gttggctgtt ccaccaagat ttccttggct tgtctaggaa
    20821 aggatatttg agagaggata aacaaggctt gttgggttcc agaagtcagt actagttggt
    20881 tagccttgca gtagagagct tgctcaaaga ggagtttgtg aatggactgt cttaggtctt
    20941 ctaatccttc ttgattgtca tagtagttga agaggtagtt ttctcggcca atcaaggttt
    21001 cattgacaca gagtcggaaa tcgtcatagg cactggcatg ttcgtcggta acctcgattt
    21061 ctaggtcttg atgttgccct tgttctaata catagtagcc actctgaggc ttggcataga
    21121 ggtattgttc gtgccgtaat tccagcaggg ctcgttgaat ggtgtccttg ctgcagtgaa
    21181 agtcaaggct cagttgacgg atagaaggca ggcgactacc cgtcggaaat cgttcagact
    21241 cgataccatt tttcagatag gaaacgacct ctttgtactt gctttgtttc ttcattccag
    21301 acctcccttg attttgttac attgtaccct tttttttcct tcttggcaat gtctagagcg
    21361 tttctctcgt tcacatctag gggcaaatgt ggtatactta ggagtaagat ttatagaata
    21421 acagacaaga aagtgaatgg ataagaacgt gcaggaacca gtgaaattat ttcaatacaa
    21481 tactcttgga gccttgatgg ctggccttta tggtggtact atgacagtag gagaattgct
    21541 agaacatggt gaccttggtt tgggaacctt ggattccatt gatggggaat tgattgtctt
    21601 ggatggcaag gcttatcagg ccaaagggtc aggagaccag ccagaaattg tggaagtgtc
    21661 accagatgcc cttattcctt acgctgcagt ggtaccgcat caggcagagg tcattttccg
    21721 ccagcgcttt gagatgacag acaaggaatt gaaagaacga attgagtctt attatgatgg
    21781 ggaaaatctt ttccgttcta tcaagattcg gggggaattt tcacatatgc atgtgcgtat
    21841 gattcctaag tcaacacccg ataccaagtt tgctgatgtc gcaacccatc aaccggaata
    21901 tagtcgtgac aatgttgcgg ggactattgt tggtttctgg acgcctgaga ttttccatgg
    21961 ggtcagtgtg gcaggctacc atctgcactt catatcagat gatttgacct tcggtggaca
    22021 tgtcatggat tttgtcatca aggaaggcat tatcgaggtg ggagcagttg accagttgga
    22081 ccaacgtttc ccagtccaag accgtcaata cttgtttgct aagttcaatg ttgacgagat
    22141 gaaaaaagat attgaaaagg cagaatagga gaagaaaatg accattcata tcattattac
    22201 catgttgctg ttgctagctt ttctgatagg aagcatttgg tttgccaaaa agaaatacca
    22261 gattaatcta gctgtcttgg gcttgggtgc agtcgctttc tttgtctctt cgcagatttt
    22321 ggaaaaactg gtgcatatct tgattttgca tcctcaaaaa agacggtagt attgccctct
    22381 tgcaagatca cccgcttgtc tatattatct atggcctagc tatggcagca ttttttgagg
    22441 aaacggctcg tcttgttttc ttcaaatggt tggagaaaaa gagaagtttg gaaaaggcag
    22501 acgccttggc ctatggactg gggcatggtg gcttggagtt gatttttcta ggccttacta
    22561 gtttactcaa tctttacatt gttctttcgg cagttcaaac tcagaatcca caggttatgc
    22621 aattactgtc tgaaaatatg ttaaaaacca ttcagtcact ttcggtctgg cagatttatt
    22681 tgcttggttt tgagcgaatc ttggcgcttg gtttccaatt acttttgaca gtttgggttt
    22741 accaagctgt tcgccagaag aaatggattt atctcctagc agcctatggc ttgcatgcct
    22801 tctttgatct ggcaccatct ctttcccaag taggctggtt gacaaatcca gtcttggttg
    22861 aagtgattct agcactggag ctcgttctgg tcgcctatgg aaccaaggaa atcttttgta
    22921 aaaaatcata aaaaggggga aacctctttt tcttatgcaa aatccaaaca aggtattttt
    22981 atggtcgtca aatgtctcta aaaatggtat aatggaatga attttgtaaa aggaagagtg
    23041 acatgtctgt aagagaaaaa atgcttgaaa tcttagaagg aattgatatc cgttttcagg
    23101 aacccttgca tagctatagt tatacaaaag taggtggaga ggctgattat ttggtctttc
    23161 cacgaaatcg ttttgagttg gctcgcgttg tgaaatttgc caaccaagaa aatatccctt
    23221 ggatggttct tggcaatgca agcaatatca tcgttcgtga tggtgggatt cgtggatttg
    23281 tcatcttgtg tgacaagctc aataacgttt ctgttgatgg ctataccatt gaagcagaag
    23341 ctggggctaa cttgattgaa acaactcgca ttgccctccg tcatagttta actggctttg
    23401 agtttgcttg tggtattcca ggaagcgttg gcggtgctgt ctttatgaat gcgggtgcct
    23461 atggtggcga gattgctcac atcttgcagt cttgtaaggt cttgaccaag gatggagaaa
    23521 tcgaaaccct gtctgctaaa gacttggctt ttggttaccg ccattcagct attcaggagt
    23581 ctggtgcagt tgtcttgtca gttaaatttg ccctagctcc aggaacccat caggttatca
    23641 agcaggaaat ggaccgcttg acgcacctac gtgaactcaa gcaacctttg gaatacccat
    23701 cttgtggctc ggtctttaag cgtccagtcg ggcattttgc aggtcagtta atttcagaag
    23761 ctggcttgaa aggctatcgt atcggtggcg tagaagtgtc agaaaagcat gcaggattta
    23821 tgatcaatgt cgcagatgga acggccaaag actacgagga cttgatccaa tcggttatcg
    23881 aaaaagtcaa ggaacactca ggtattacgc ttgaaagaga agtccggatc ttgggtgaaa
    23941 gcctatcggt agcgaagatg tatgcaggtg gttttactcc ctgcaagagg tagtggggac
    24001 ctgacagagc cccgatcggt taatctatga aaaagaagga atttatgcca attgaaaaaa
    24061 ccaattatcg aattcaaaaa cgtctctaaa gtttttgaag acagcaacac caaggttctc
    24121 aaagacatca actttgagtt ggaagaaggg aaattctaca cccttctagg tgcatctggt
    24181 tcggggaaat caactatcct aaacattatt gcaggtttac tggatgcgac gacaggagat
    24241 atcatgctag acggtgttcg tatcaatgat attccaacca acaagcgcga cgtacatacc
    24301 gtcttccaat cctatgcctt gttcccacat atgaatgtgt ttgaaaatgt tgcctttcca
    24361 cttcgcttgc gtaaaattga taagaaagaa atcgagcagc gtgtagcgga agttctcaag
    24421 atggttcagt tggaaggtta tgaaaaacgt tccatccgca aactttctgg aggacaacgt
    24481 cagcgtgtgg ccatcgcccg tgctatcatc aaccaacccc gtgtggtctt gttggacgag
    24541 cctttatcag cgctggactt gaaattgaga acagacatgc agtacgaatt gcgtgaatta
    24601 caacaacgat tgggcattac ctttgtcttt gtcactcacg atcaggaaga agctcttgcc
    24661 atgagtgact ggattttcgt tatgaatgat ggcgagattg tccagtctgg aacccctgtg
    24721 gacatctacg atgagccaat caaccacttt gttgccacct ttatcgggga gtcaaacatc
    24781 ttgccaggta ccatgattga ggactacttg gtcgaattta acggcaaacg ctttgaagcg
    24841 gttgatggtg ggatgaagcc aaatgaacct gttgaggtcg ttattcgtcc agaggacttg
    24901 cgcattaccc ttcctgaaga aggcaaactc caagttaagg tcgacaccca gctcttccgt
    24961 ggagttcatt atgaaattat cgcctatgac gaacttggaa atgaatggat gatccactca
    25021 acccgtaagg ccatcgtggg tgaggaaatc ggtctggact ttgaatcaga agacatccac
    25081 atcatgcgtc tcaatgaaac cgaagaagag ttcgatgctc gtatcgaaga atacgtggaa
    25141 atcgaagagc aagaagcagg tttgatcaat gcaatcgagg aggaaagaga tgaagaaaac
    25201 aagctctaaa ctctttgtag tgccctacat gctttggatt gccctctttg tattggcacc
    25261 cttggtcttg attttcggac aatccttttt caacattgaa ggccagttta gtttagaaaa
    25321 ttataaatct tactttgcgt cacaaaactt gacctacctc aaaatgagtt tcaactcagt
    25381 gctttatgca gggattgtga cctttgtgac cttgcttatc agctatccaa cagccctctt
    25441 tttgacccgt ctcaagcacc gtcaactctg gctcatgctg attatccttc ctacctggat
    25501 caatttgctc cttaaagcct atgcttttat cgggattttt ggtcaaaatg gctctattaa
    25561 ccaattcttg gaatttatcg gaattggttc acaacagttg ctttttaccg atttttcctt
    25621 tatctttgtc gcaagctaca tcgagctccc ctttatgatt ttgccgattt tcaatgtctt
    25681 agacgatatg gataataatc tcatcaatgc tagttatgac cttggtgcaa ctaagtggga
    25741 gaccttccgt catgtcatct tccctctatc tatgaacggt gtgcgaagtg gggttcagtc
    25801 ggtctttatc ccaagtttga gtctcttcat gctgacccgt ttgattggtg ggaaccgcgt
    25861 tatcaccttg gggacggcta ttgagcagaa ttttctaacc aatgacaact atggtatggg
    25921 ttcaaccatc ggtgtgattc tcatcctgac catgttcatc accatgtggg tgactaagga
    25981 aaggagagaa cgatgaaaaa atttgccaac ctttatctgg gactggtctt tctggtcctc
    26041 tacctgccta tcttttactt gattggctat gcctttaatg ctggtgatga tatgaatagc
    26101 tttacaggtt ttagctggac tcactttgaa accatgtttg gagatgggag actcatgctg
    26161 attttggctc agacattttt cttggccttc ctatcagcct tgatagcgac cattatcggg
    26221 acttttggtg ccatttacat ctaccagtct cgtaagaaat accaagaagc ctttctatca
    26281 ctcaataata tcctcatggt tgcgcctgac gttatgattg gtgctagctt cttgattctc
    26341 tttacccaac tcaagttttc acttggcttt ttgaccgttc tatctagtca cgtggccttc
    26401 tccattccta tcgtggtctt gatggtcttg cctcgactca aggaaatgaa tggcgacatg
    26461 attcatgcgg cctatgactt gggagctagt caatttcaga tgttcaagga aatcatgctt
    26521 ccttacctga ctccgtctat cattactggt tatttcatgg ccttcaccta ttcgttagat
    26581 gactttgccg tgaccttctt tgtaacagga aatggctttt caaccctatc agtcgagatt
    26641 tactctcgtg ctcgcaaggg gatttcctta gaaatcaatg ccctgtctgc tctagtcttt
    26701 ctctttagta ttatcctagt tgtaagttat tactttatct ctcgtgagaa ggaggagcaa
    26761 gcatgaaaaa aatctattca tttttagcag gaattgcagc gattatcctt gtcttgtggg
    26821 gaattgcgac tcatttagat agtaaaatca atagtcgaga tagtcaaaaa ttggttatct
    26881 ataactgggg agactatatc gatcctgaac tcttgactca gtttacagaa gaaacaggaa
    26941 ttcaagttca gtacgagact tttgactcca acgaagccat gtacactaag ataaagcagg
    27001 gtggaacgac ctacgatatt gccattccaa gtgaatacat gattaacaag atgaaggacg
    27061 aagacctctt ggttccgctt gattattcaa aaattgaagg aatcgaaaat atcggaccag
    27121 agtttctcaa ccagtccttt gacccaggta ataaattctc catcccttac ttctggggaa
    27181 ccttaggaat tgtctacaac gaaaccatgg tagatgaagc gcctgagcat tgggatgacc
    27241 tttggaagcc ggagtataag aattctatca tgctctttga tggggcgcgt gaggtgctgg
    27301 gactaggact caattccctc ggctacagcc tcaactccaa ggatctgcag cagttggaag
    27361 agacagtgga taagctctac aaactgactc caaatatcaa ggctatcgtt gcggacgaga
    27421 tgaagggcta catgattcag aataatgttg caatcggcgt gaccttctct ggtgaagcca
    27481 gccaaatgtt agaaaaaaat gaaaatctac gttatgtggt accgacagag gccagcaatc
    27541 tttggtttga caatatggtc attcccaaaa cagttaaaaa tcaagactca gcctatgcct
    27601 ttatcaactt tatgttgaaa cctgaaaacg ctctccaaaa tgcggagtat gtcggctatt
    27661 caacaccaaa cctaccagcg aaggaattgc tcccagagga aacaaaggaa gataaggcct
    27721 tctatcccga tgttgaaacc atgaaacacc tagaagttta tgagaaattt gaccataaat
    27781 ggacagggaa atatagcgac ctcttcctac agtttaaaat gtatcggaag taggagataa
    27841 acgtaagaag acgaatcagt caagctggtt cgtttttaag gaatagaagt cagtttttag
    27901 agccctatct ttttctattc tagttgttta tttgcttgcc tagtagtata ctaagcctat
    27961 actcttcaaa ccacgtcagc gttgccttgc cgtactcaag tacagcttga ggctagcttc
    28021 ctagtttgct ttttgatttt tattgagtat taaccttaca gaaagcggca acaaataatg
    28081 aaaatgtcta cttttttcaa aaaaagtttc tggccaacct ttatgattgt taaccaaact
    28141 gttatactat tccatttaaa ggatggcttg gatcgacaat acctaacaac tgagtccata
    28201 tattgggtga taggcacctt tatatttgga aatattctag tagctgtgtt tagtaatatg
    28261 aaaatttggg ataaaaagaa aaacggcagt aagaaaaaat atatcctgaa aaagtaatca
    28321 gagatgtagg gaattggtct aattcaacgg agatcatttc cagttgacgc aagcttaaaa
    28381 aaacgttata ataagaaagt tgagaattga ttttcacttg tcttagtcca gagaaatggc
    28441 ggtgctgcga gccatctaag ctaggaagtc atgctactca atcatacaat tgcataagaa
    28501 caagagaatg acaagttcat tgaatgaagg tggtaccgcg gtttttcgcc cttcgtgata
    28561 tgagcttgtc ttttgatttt tggaggtgtt gatgaaaaca tttcttgtca aacaaaagtt
    28621 tcgtcttgga ggcgaacgct tcgctatcaa ggatgacagg ggagaaattg cctatcaggt
    28681 ggagggatca ttttttaaga ttcccaaaac ttttaccatc tatgatgcgg ctggtgaaca
    28741 agtcagtcag atcagtaaag aaatcttgac cttgcttcct cgttttgaga ttcagcttcg
    28801 ggatggctcg agttttgtca ttcgtaagaa gttgaccttt tggcgagata agtatgagtt
    28861 tgataatcta ggtcttcgta tcgagggcaa tatctgggat ttgaatttca aattgctgga
    28921 tgatcgcgat cagttgattg cggaaattaa gaaggaactc ttccatctga cctctaccta
    28981 taccgtaacg gttcttgaag acgcttatgc agacctagtc atttccctct gtgtcgcgat
    29041 tgactatgtg gaaatactgg aaagccaatc acattaaaca agtgaataag gagacaatat
    29101 gaaacaacta tctagtgcac aagtacgcca aatgtggctt gatttctggt cgaccaaagg
    29161 tcactcagta gaaccatcag taagtttggt tcctgtaaat gacccaactc ttttgtggat
    29221 caactctggg gtagcaaccc ttaagaaata ctttgacggg accattatcc ctgaaaatcc
    29281 acgtattacc aatgcccaaa aggctatccg taccaacgac atcgaaaacg tagggaagac
    29341 tgcgcgtcac cataccatgt ttgaaatgtt ggggaacttc tctatcgggg attacttccg
    29401 tgacgaagct atcacttggg cttatgagct tttgacaagc cctgaatggt ttgatttccc
    29461 tgctgaaaaa ctttacatga cctactatcc agacgataaa gattcttaca accgctggat
    29521 tgaagtggga gtggatccaa gtcacttgat tccaattgag gacaacttct gggaaatcgg
    29581 tgcgggacct tctggaccag atacagaaat cttctttgac cgtggggaag cctttgaccc
    29641 agaaaatatc ggtcttcgcc tgcttgcaga agatattgaa aacgaccgtt atattgaaat
    29701 ctggaacatc gttttgtcac aatttaacgc agaccctgct gttcctcgta gcgaatacaa
    29761 ggaattgcca cataagaaca ttgatacggg cgctggtttg gagcgtttgg tggctgttat
    29821 ccaaggggct aagaccaact ttgaaacgga cctcttcatg ccgattatcc gtgaagtcga
    29881 gaaattgtct ggtaaggttt atgaccaaga tggcgacaac atgagcttca aggttatcgc
    29941 agaccacatt cgttctcttt catttgctat cggtgatggt gcccttccag gaaatgaagg
    30001 tcgtggttat gttcttcgtc gtcttctccg tcgtgcttct atgcatggtc aaaaattggg
    30061 tatcaacgag cctttccttt acaaattggt tccaactgtt ggaaaaatca tggaaagcta
    30121 ctacccagaa gtgcttgaga aacgtgactt tattgagaaa atcgttaaga gcgaagaaga
    30181 atcatttgcc cgtacccttc actcaggtca acactttgcc caaggcattg tagcagactt
    30241 gaaagaaaaa ggtcaatctg ttatcgctgg ttcagatgtc ttcaaactct atgatactta
    30301 tgggttccca gttgaattga ctgaagaaat cgctgaagaa gctggtatga ctgtagaccg
    30361 tgaaggtttt gaagcagcca tgaaagaaca gcaagaacgc gcgcgtgcct cagctgtcaa
    30421 gggtggctca atgggtatgc aaaatgaaac tcttcaaaac atcactgtag aaagtgtctt
    30481 caactacaat gctagccaat tgtcttctaa attggtagct atcgtggcgg acaatgcaga
    30541 agtagaagct gtttcagaag gaactgcctc tcttatcttt gcggaaacgt cattttatgc
    30601 tgaaatgggt ggacaggtag ctgactacgg acaaatcttg gatgagtcag gtaaggttgt
    30661 ggctactgtg accaatgttc agaaagcccc aaatggtcaa gcccttcata cagttgaagt
    30721 ccttgcaccg cttgccttga accaagaata taccttggca attgatagca atcgccgtca
    30781 ccgtgtcatg aaaaaccaca ctgcgactca tttgcttcac gctgcccttc acaatatcct
    30841 tggaaaccac gcaacacagg caggatctct taacgaagtt gaattccttc gctttgactt
    30901 tacccacttc caagctgtaa ctgctgaaga attgcgtgcg attgaacagc aagtcaacga
    30961 aaaaatctgg gaagctcttg aagttaagac agttgaaacg gatattgaca ctgctaaaga
    31021 aatgggagct atggccctct ttggtgagaa atacggcaag gaagttcgtg tcgtgactat
    31081 cggtgactac tctattgaac tttgtggtgg tactcatgtt ggcaacactt ctgagattgg
    31141 tctcttcaaa attgtcaaag aagaaggaat cggttcagga actcgccgta tcttggcagt
    31201 gactggtaag gaagcctttg aagcctatcg tgaacaagag gatgctctta aagctgtcgc
    31261 agcaaccttg aaagcacctc aagtcaagga agtacctcac aaggtagaag gacttcaaga
    31321 acaacttcgt caacttcaaa aagaaaatgc tgagttgaaa gaaaaagccg cagctgcagc
    31381 cgcaggcgat atcttcaaag atgctaagga agtcaacggt catcgttaca ttgctagtca
    31441 agtgtctgta tccgatgccg gtgcccttcg tacttttgca gataactgga aacaaaaaga
    31501 ctactctgat cttcttgtcc tagttgccgc tatcggtgac aaagtcaatg tccttgtagc
    31561 aagcaagaca aaagaccttc atgcaggaaa ccttgtcaaa gaattagcac caatcatcga
    31621 tggacgtggt ggtggtaaac cagacatggc catggcagga ggaagcaacc aagctaagat
    31681 ccaagaattg ttggatgcag tagcaggtaa attgtaatca agtaaagatc tatccatttg
    31741 ggtaggtctt tttgtgaata caaaaaagcc aaatccgctt ggacctagct tggttattat
    31801 gagctattag atggtattga ctgcccagac acttacggat ctagctgaga cagggaattg
    31861 tccataacct tcctcatcaa ttgtaacttg accttggtgg ttaccaagta aatctacaaa
    31921 ggtttgatta gtccattctt gaccgacaaa cattgacttg ctgttttctt ggtcatttga
    31981 gataaggact gcgattgggg attgattttc agcacctgaa cgtacccaac cgatacagtt
    32041 agcatggtca aagtagtcat tttgttctcc ataggccaaa tcttttcgga tggctaggag
    32101 gcggtcaagg atttctttga aatcttgttg agcatactgc cctgaaatcc catagtagtc
    32161 tccgtaaaag acacatggaa ggccgtcttg gcgtaacaaa atgagggcat aggctgctgg
    32221 cttgaaccat tcttcaacgg tagactcaag ggcttgtcct cgttgggtat cgtggttgtc
    32281 gacaaaagtc acagccttgt caggcttgag ttcaaccagg ctatctgtga aaatgccacg
    32341 aaggtcatag tttgcgccag cttgactggc ttcaaagaga ttctggtgga gacgaacatc
    32401 gacaaggtca aagtgttctt ccgttttttc gagatagtcc agattggctt ccttgtctgg
    32461 gttccaaaat tcaccaaaaa catagaaatc gtcaccgtat ttttccttca tatcgcggat
    32521 gaagttgcgc ataaagaaag agtcaatatg cttaacggca tccaaacgga aaccagctac
    32581 accagtcgtt tccatgaacc aatcagccca gtcatagatg ttttggatga cttcaggatg
    32641 tttaaagtct aggtcggcat acatgaggta gtcgtagttt ccgttttcgt tatcgaccaa
    32701 ttcctcgtta gcccagccct tgttgtcccc ttggatcaga taaatcccag atttactgcg
    32761 tttggcatcg tagtctgtac cggtgaagtg gtaccaatgc cagtggaagc cattataggt
    32821 atcttggcga ccatcgaagg taaaactagt ccagccattg atggtgaagg gttctccaag
    32881 ttcaactgta cggtctacag gatcaacttc gatgacctga aaggcttccc tgtgatcggc
    32941 agcagccttg tggttgagaa ctacatcggc cataggttga attccctgtg ctttaagggc
    33001 ttgaatggct tgaagatagt cttctttgaa accatacttg gtgcggacag tccctttttg
    33061 gttgaactct cctaagtcaa ataagtcata gaccccatag ccgacatctt tttcgttggt
    33121 tgccttgaag gctggtggca tccagacgtg actgatcccc agatgagcta ggtgtggagc
    33181 attttcagcc agacgcgtcc agtgttgacc gtcgtggggc agataccatt caaagtattg
    33241 catgagtgtt tgattttgca tgatgtttcc tcttacttgt caatcttgtt ctttattcta
    33301 tcataaagta tctcttggcg caaacgtttg cgtaagatag aaggaaacta ttttaactac
    33361 ttaaaataaa gtattgattt ttttgtatca aagtgctagt atagcgatgt ataatacaga
    33421 taaagatagg agttgtccca tgattgaatt tcaaaatgtt agtaagttgt atggtgataa
    33481 agaggccttg agtaatctca atttgcagat tgaaaatgga gagattatgg gcttgattgg
    33541 tcataatggg gctggaaaat cgaccaccat aaaatcccta gtcagtatca tttcacccag
    33601 cagtggtcgt attttggtag acggtcagga gttatcggaa aatcgcttgg ctattaaacg
    33661 aaagattggc tacgtagcag actcgcctga cttattttta cgcttaacgg ccaatgaatt
    33721 ttgggaattg atcgcctcat cctatgatct gagtagatct gacttggagg ctagtctagc
    33781 taggctattg aacgtttttg attttgctga aaatcgctat caggttattg aaactctttc
    33841 tcacggaatg cgtcagaaag tctttgtcat cggagcactc ttgtctgatc ccgatatttg
    33901 ggtcttggat gaacccttga ctggtttgga tccccaggct gcctttgatt tgaaacagat
    33961 gatgaaggaa catgcacaaa aagggaagac agtcttgttt tcaactcatg tcctagaggt
    34021 ggcagagcaa gtctgtgatc ggattgccat tttgaaaaag gggcatttga tttattgtgg
    34081 taaggtagag gacttgagga aagaccaccc agaccagtct ttggaaagta tctaccttag
    34141 tcttgctggt agaaaagagg aggttgcgga tgcgtctcaa ggtcattaaa aaattagttg
    34201 atatcaatat cctctattca tctcaagaag ctaatctggc taatctacga aagaagcagg
    34261 ctaagaatcc tgggaaaaaa gtaaatgttt ccgctagagt cctaagttct tacatttttt
    34321 ccagtctctt gatgctcatc tgttttagta atatagccat tcattttcct tttgaggaaa
    34381 tacctattta ttttagctcg atggttgcta ttttactagt gattgccttt tcaacttctt
    34441 taacggcctt ttacaatgtc ttttatgaga gtaaggattt ggtatcgtat aggccctatg
    34501 cctttaaaga atcagagatt ataattgcta aaggactgtc tgtccttttg ccagctctaa
    34561 ctggaattgt accaatccta gcttattttc tagtcctcta cattaggcta gctccttctc
    34621 tatggctggg tttgcctttg atgctactgt ccttgacctt attatttgtc tctgtggctc
    34681 tagtgatggt agtggcagtg catttcttgg ctcaaactac ggtcttcaga aagtatcagt
    34741 ctattttttc gaatgtgatg attgggatag gagttctcat acctttaata tttgtcttct
    34801 ttctacagtc gacttttgga agtattgttg acaaagttag agacattcca tttctccttt
    34861 atcctcttca tatcttttac aaaatagcag tggagccttt ttcaatagaa gccatattgg
    34921 gtctgctcgc ttggatagct ttaactgttt tcttgcttta cctgaccaaa aagaaggtcc
    34981 ttcctcgttt ttatgacgtg atcctgctta acagtgagga gaaggtcaaa aaagaacgtc
    35041 gcagcaagga gaggatttca actactaaaa agggcttttt ccgtatggtt ttacgctacc
    35101 acctcaccct cttgggacag gggactggcg tgattacagt gctttttaca agtgctttcc
    35161 ttccttatct catgatgatc agtctgattt ccaaaatccg agattctcag atagttccag
    35221 acattcatcc tccatactgg ttacccttgt tttttgtagg agtgtttata gcagttgtca
    35281 ataacaatat caccagcctg cattcaattg ccttgtcctt ggagagggaa aatcttgatt
    35341 ttctgaagag tttacccttt gactttgctc gttatgtgaa agtgaaattt tggattatct
    35401 ttgctgttca gtccttttta ccaattctga ctttgctcgg tctttctcta tatctaggct
    35461 tgtccatcct ttcgatgatt taccttcttg tagtctggat cattgccagt gtcatccttt
    35521 cttgccacca ttactttaag gacgttaaaa atctgtcaac caattggagt agcattacgg
    35581 acctggtgaa tcgttcaaat ggcatagtcg ccatagtttt attgtttatt tatagtgcaa
    35641 tcctgatggc ccttgtaatt gggagcatat tcttggttca gtctctctcc cctatccttg
    35701 ccatcaactt gggagtagga gctcttatcg tcttgcttgc tcttgctatt tttggctatc
    35761 attattacct gtcacgcata ttggcagaaa tagaaaaaag atgagatagt tggttgcttg
    35821 cttgataaat tcaattcgac aaacgctttt atagtttgtt agaatgtagt tgtaaatgat
    35881 taagattggt aatcaaaaat atagggagga atgttttgaa taagaaatat aatatagttc
    35941 tattattgtt gtttatagtt tatttattgg gatatttttc aatttca
//
LOCUS       DAVMCG010000016        34607 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVMCG010000016 DAVMCG010000000
VERSION     DAVMCG010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.016"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            770..1222
                     /locus_tag="VYP66_000997"
     CDS             770..1222
                     /locus_tag="VYP66_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1850563.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1241..2578
                     /locus_tag="VYP66_000998"
     CDS             1241..2578
                     /locus_tag="VYP66_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1850564.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2657..3541
                     /locus_tag="VYP66_000999"
     CDS             2657..3541
                     /locus_tag="VYP66_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1850565.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3541..4374
                     /locus_tag="VYP66_001000"
     CDS             3541..4374
                     /locus_tag="VYP66_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1850566.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4392..6485
                     /gene="nanB"
                     /locus_tag="VYP66_001001"
     CDS             4392..6485
                     /gene="nanB"
                     /locus_tag="VYP66_001001"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1850567.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6497..7600
                     /locus_tag="VYP66_001002"
     CDS             6497..7600
                     /locus_tag="VYP66_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1850568.1"
                     /translation="MVKYGVVGTGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7774..8472
                     /locus_tag="VYP66_001003"
     CDS             7774..8472
                     /locus_tag="VYP66_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1850569.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8491..10008
                     /locus_tag="VYP66_001004"
     CDS             8491..10008
                     /locus_tag="VYP66_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1850570.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            10133..11461
                     /locus_tag="VYP66_001005"
     CDS             10133..11461
                     /locus_tag="VYP66_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1850571.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11713..12579
                     /locus_tag="VYP66_001006"
     CDS             11713..12579
                     /locus_tag="VYP66_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1850572.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12595..13434
                     /locus_tag="VYP66_001007"
     CDS             12595..13434
                     /locus_tag="VYP66_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1850573.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13706..14158
                     /locus_tag="VYP66_001008"
     CDS             13706..14158
                     /locus_tag="VYP66_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1850574.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14255..14599
                     /locus_tag="VYP66_001009"
     CDS             14255..14599
                     /locus_tag="VYP66_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850575.1"
                     /translation="MVSSKYAARASFLDGQGITVDEMAWIIRGIVNALIGRYIKLGTY
                     AAKYGISMARSILSRVAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            14876..15520
                     /locus_tag="VYP66_001010"
     CDS             14876..15520
                     /locus_tag="VYP66_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1850576.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15689..16606
                     /locus_tag="VYP66_001011"
     CDS             15689..16606
                     /locus_tag="VYP66_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1850577.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEVLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16624..17508
                     /locus_tag="VYP66_001012"
     CDS             16624..17508
                     /locus_tag="VYP66_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1850578.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17524..18375)
                     /locus_tag="VYP66_001013"
     CDS             complement(17524..18375)
                     /locus_tag="VYP66_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1850579.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18575..20632
                     /gene="pbp2b"
                     /locus_tag="VYP66_001014"
     CDS             18575..20632
                     /gene="pbp2b"
                     /locus_tag="VYP66_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1850580.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20643..21239
                     /gene="recR"
                     /locus_tag="VYP66_001015"
     CDS             20643..21239
                     /gene="recR"
                     /locus_tag="VYP66_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1850581.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21415..22458
                     /locus_tag="VYP66_001016"
     CDS             21415..22458
                     /locus_tag="VYP66_001016"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1850582.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNNITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPKLIERLVDL
                     AKESFDKREAHLI"
     gene            22542..23915
                     /locus_tag="VYP66_001017"
     CDS             22542..23915
                     /locus_tag="VYP66_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1850583.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQDLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDTVIFYGQDIAQ
                     LVQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            23902..24513
                     /locus_tag="VYP66_001018"
     CDS             23902..24513
                     /locus_tag="VYP66_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1850584.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            24604..25308
                     /locus_tag="VYP66_001019"
     CDS             24604..25308
                     /locus_tag="VYP66_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1850585.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25527..26900
                     /gene="ftsA"
                     /locus_tag="VYP66_001020"
     CDS             25527..26900
                     /gene="ftsA"
                     /locus_tag="VYP66_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1850586.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26917..28176
                     /gene="ftsZ"
                     /locus_tag="VYP66_001021"
     CDS             26917..28176
                     /gene="ftsZ"
                     /locus_tag="VYP66_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1850587.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28181..28852
                     /locus_tag="VYP66_001022"
     CDS             28181..28852
                     /locus_tag="VYP66_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1850588.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28862..29401
                     /locus_tag="VYP66_001023"
     CDS             28862..29401
                     /locus_tag="VYP66_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1850589.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTSVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29401..29664
                     /locus_tag="VYP66_001024"
     CDS             29401..29664
                     /locus_tag="VYP66_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1850590.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29661..30458
                     /locus_tag="VYP66_001025"
     CDS             29661..30458
                     /locus_tag="VYP66_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1850591.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFLTPFIN
                     PHQEKLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNK
                     FEHLTHAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPV
                     SLEERPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYH
                     VVDKSDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30467..31255
                     /gene="divIVA"
                     /locus_tag="VYP66_001026"
     CDS             30467..31255
                     /gene="divIVA"
                     /locus_tag="VYP66_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1850592.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31603..34395
                     /locus_tag="VYP66_001027"
     CDS             31603..34395
                     /locus_tag="VYP66_001027"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1850593.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEYGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERATGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10654 a         6094 c         7498 g        10361 t
ORIGIN      
        1 attatatgac tattaacctt gtcttctcct aaaattgact ttcttgtttt cttatcttgt
       61 ccactcgaaa caagtattgt aagaatttga ttatttttga aagtactttt aatatacttg
      121 atatagttaa aaaagatttg aaactaaatt ccaaattaga aaaagacttg aaatactaaa
      181 aaaaaaaagt atactctaat tgaaaacggt aacaaaacta atttagagaa tgaaatatag
      241 agtatttctc tcttaaaagt ttttggtgaa acgagatgta gaaaggagat ttagccaaag
      301 agtctattag tgctagaata atagattaga attattttag aaaaacgaag tgagcagctt
      361 ataaattcaa gtccccaaat agattcatac tagtatcttt tgcaaaaaat aaagggcgac
      421 ttccttcatg aatatcaatt tcatctataa ggaaggtagc taattgaact aacttattta
      481 ttctgtttgt cgctagaaaa atcagacctc cttgtgaaga ttgaggagat acttaatgaa
      541 aatcaaagaa gaaactagca agctagtagc agattgccca aaacaccgct ttgaggttgt
      601 agataagact gacctatata atccaaggtg aagcgactgt ggtttgaaga gattttcaaa
      661 gagtataggc tagagagtag tgtttttatg tccttctagt agaaaatgct agacagaaga
      721 atggggaact tggataggaa aaatagattg agaaaggagg ttagaagaga tgattattac
      781 aaaaattagc cgtttaggaa cttatgtggg agtaaatcca cattttgcaa cattaataga
      841 ttttctagaa aaaacaggac tagaaaattt aacagaaggt tcgattgcta tcgatggtaa
      901 tcgattgttt gggaattgct ttacttatct agcagatggt caagcagggg ctttctttga
      961 aacccaccaa aaatatttgg atattcattt agttttggaa aacgaagaag ccatggctgt
     1021 tacatcgccg gaaaatgtaa gcgttaccca agaatatgat gaagagaaag atattgaatt
     1081 atacacaggg aaagtggaac agttggttca tttgagagct ggcgaatgcc tcatcacttt
     1141 tccagaagat ttacatcaac ccaaggttcg tataaatgat gaacctgtga aaaaagttgt
     1201 ctttaaagtt gcgatttctt aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt
     1261 tttatgtcta gctggaattg cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa
     1321 agaagctaca actagtactg aaccaccaac agaattatct ggtgagatta caatgtggca
     1381 ctcctttact caaggacccc gtttagaaag tattcaaaaa tcagcagatg ctttcatgca
     1441 aaagcatcca aaaacgaaaa tcaagattga aacattttct tggaatgact tctatactaa
     1501 atggactaca ggtttagcaa atggaaatgt gccagatatc agtacagctc ttcctaacca
     1561 agtaatggaa atggtcaact cagatgcttt ggttccgcta aatgattcta tcaagcgtat
     1621 tggacaagat aaatttaacg aaactgcctt aaatgaagca aaaatcggag atgattacta
     1681 ctctgttcct ctttattcac atgcacaagt catgtgggtt agaacagatt tgttaaaaga
     1741 acataatatt gaggttccta aaacttggga tcaactctat gaagcttcta aaaaattgaa
     1801 agaagctgga gtttatggct tgtctgttcc gtttggaaca aatgacttaa tggcaacacg
     1861 tttcttgaac ttctacgtac gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc
     1921 agacttgaca agccaacttg ctcaagatgg tattaaatac tgggttaaat tgtataaaga
     1981 aatctcacct caagattctt tgaactttaa tgtccttcaa caagctacct tgttctatca
     2041 aggaaaaaca gcatttgact ttaactctgg cttccatatc ggaggaatta atgccaacag
     2101 tcctcaattg attgattcga ttgatgctta tcctattcca aaaatcaaag agtctgataa
     2161 agaccaagga attgaaacct caaacattcc aatggttgtt tggaaaaatt caaaacatcc
     2221 agaagttgct aaagcattct tagaagcact ttataatgaa gaagactacg ttaaattcct
     2281 tgattcaact ccagtaggta tgttgccaac tattaagggg attagcgatt ctgcagccta
     2341 taaagaaaat gaaactcgta agaaatttaa acatgctgaa gaagtaatta ctgaagctgt
     2401 taaaaaaggt actgctattg gttatgaaaa tgggccaagt gtacaagctg gtatgttgac
     2461 taaccaacac attattgaac aaatgttcca agatatcatt acaaatggaa cagatcctat
     2521 gaaagcagca aaagaagcag aaaaacaatt aaatgattta tttgaggctg ttcagtagat
     2581 gtaaaagact agaaaatagg tgggatagtg agctgaaaag ctctagccca atcttgtaaa
     2641 agaagggaga aggagaatgg ttaaagaacg taatttaact cgctggatat ttgttttgcc
     2701 agctatgatt atcgtaggat tactctttgt ttatccgttt ttctcgagta ttttttatag
     2761 ctttaccaat aagcatttga ttatgcctaa ttataaattt gttggtttgg ctaactataa
     2821 agctgtgcta tcagatccca acttctttaa tgcgttcttt aattcaatta agtggaccgt
     2881 tttctcatta gttggtcaag ttttagtagg gtttgtattg gctttagctc ttcacagagt
     2941 acgccacttc aagaaattat ataggacatt attgattgtt ccttgggcat ttcctaccat
     3001 cgttattgcc ttctcttggc agtggattct aaacggggtt tatggctact tacctaatct
     3061 aatcgtaaaa ttaggtttaa tggaacatac acctgcattt ttgacagata gtacatgggc
     3121 attcctatgt ttggtgttta tcaacatttg gtttggagca ccaatgatta tggttaatgt
     3181 gctttcagct ttgcaaacag taccagaaga acaatttgag gctgctaaga tagatggtgc
     3241 ttcaagttgg caggtgttca agtttatcgt ctttccacat attaaagtgg ttgtaggact
     3301 tctagttgtt ttgagaactg tatggatctt taataacttt gacattatct acctcattac
     3361 tggtggtgga ccagccaatg ctacaacgac gcttccaatt tttgcttaca acctgggctg
     3421 gggaactaaa ttgttgggtc gtgcttcagc agttacagta ctgctcttta tcttcttggt
     3481 ggcgatttgc tttatctact ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata
     3541 atgaagaaga aatccagtat ttatttagat attctctcac atgtactttt agttggtgcg
     3601 accatcgttg cagttttccc attggtatgg attatcatat cttctgtcaa agggaaaggg
     3661 gaattaactc agtatccaac acgattttgg cctgaacagt ttacattaga ttatttcact
     3721 catgttatca acgatttgca cttcattgat aacattcgaa acagtttaat cattgccttg
     3781 gctacaaccc ttattgcgat tattatttct gctatggcag cctatggtat tgttcgattc
     3841 tttcctaaat tgggagcaat catgtcgaga ctactcgtca ttacctacat tttcccacca
     3901 attttgttag caattcccta ttcaattgcc attgctaaag ttgggttaac aaatagttta
     3961 tttggcttga tgatggttta tctatctttt agtgttccat atgcagtttg gctcttagtt
     4021 ggatttttcc aaacagttcc aattggaatt gaagaagcgg ctagaattga tggtgcaaat
     4081 aaatttgtta cgttttataa agttgtgcta ccgattgtag caccaggtat tgtagcaaca
     4141 gctatttata catttatcaa tgcttggaat gaattcctgt atgccttgat tttgattaac
     4201 aatacaggaa agatgacagt agcagtagcc cttcgttcac ttaatggttc agaaatacta
     4261 gactggggag atatgatggc agcgtctgtt attgtagttc ttccatcaat tattttcttc
     4321 tctatcatcc aaaataagat tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa
     4381 gaaggaaaaa aatgaataaa agaggtcttt attcaaaact aggaatttcc gttgtaggca
     4441 ttagtctttt aatgggagtc cccactttga ttcatgcgaa tgaattaaac tatggtcaac
     4501 tgtccatatc tcctattttt caaggaggtt catatcaact gaacaataag agtatagata
     4561 tcagctcttt gttattagat aaattgtctg gagagagtca gacagtagta atgaaattta
     4621 aagcagataa accaaactct cttcaagctt tgtttggcct atctaatagt aaagcaggct
     4681 ttaaaaataa ttacttttca attttcatga gagattctgg tgagataggt gtagaaataa
     4741 gagacgccca aaagggaata aattatttat tttccagacc agcttcatta tggggaaaac
     4801 ataaaggaca ggcagttgaa aatacactag tatttgtatc tgattctaaa gataaaacat
     4861 acacaatgta tgttaatgga atagaagtgt tctctgaaac agttgataca tttttgccaa
     4921 tttcaaatat aaatggtata gataaggcaa cactaggagc tgttaatcgt gaaggtaagg
     4981 aacattacct cgcaaaagga agtattgatg aaatcagtct atttaacaaa gcaattagtg
     5041 atcaggaagt ttcaactatt cccttgtcaa atccatttca gttaattttc caatcaggag
     5101 attctactca agctaactat tttagaatac cgacactata tacattaagt agtggaagag
     5161 ttctatcaag tattgatgca cgttatggtg ggactcatga ttctaaaagt aagattaata
     5221 ttgccacttc ttatagtgat gataatggga aaacgtggag tgagccaatt tttgctatga
     5281 agtttaatga ctatgaggag cagttagttt actggccacg agataataaa ttaaagaata
     5341 gtcaaattag tggaagtgct tcattcatag attcatccat tgttgaagat aaaaaatctg
     5401 ggaaaacgat attactagct gatgttatgc ctgcgggtat tggaaataat aatgcaaata
     5461 aagccgactc aggttttaaa gaaataaatg gtcattatta tttaaaacta aagaagaatg
     5521 gagataacga tttccgttat acagttagag aaaatggtgt cgtttataat gaaacaacta
     5581 ataaacctac aaattatact ataaatgata agtatgaagt tttggaggga ggaaagtctt
     5641 taacagtcga acaatattcg gttgattttg atagtggctc tttaagagaa aggcataatg
     5701 gaaaacaggt tcctatgaat gttttctaca aagattcgtt atttaaagtg actcctacta
     5761 attatatagc aatgacaact agtcagaata gaggagagag ttgggaacaa tttaagttgt
     5821 tgcctccgtt cttaggagaa aaacataatg gaacttactt atgtcccgga caaggtttag
     5881 cattaaaatc aagtaacaga ttgatttttg caacatatac tagtggagaa ctaacctatc
     5941 tcatttctga tgatagtggt caaacatgga agaaatcctc agcttcaatt ccgtttaaaa
     6001 atgcaacagc agaagcacaa atggttgaac tgagagatgg tgtgattaga acattcttta
     6061 gaaccactac aggtaagata gcttatatga ctagtagaga ttctggagaa acatggtcga
     6121 aagtttcgta tattgatgga atccaacaaa cttcatatgg cacacaagta tctgcaatta
     6181 aatactctca attaattgat ggaaaagaag cagtcatttt gagtacacca aattctagaa
     6241 gtggccgcaa gggaggccaa ttagttgtcg gtttagtcaa taaagaagat gatagtattg
     6301 attggaaata ccactatgat attgatttgc cttcgtatgg ttatgcctat tctgcgatta
     6361 cagaattgcc aaatcatcac ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa
     6421 atgaattgca tttaagcaat gtagttcagt atatagattt ggaaattaat gatttaacaa
     6481 aataaaggag aaaaacatgg ttaaatacgg tgttgttgga acagggtatt ttggagctga
     6541 attggctcgc tacatgcaaa agaatgatgg agcagagatt actcttctct atgatccaga
     6601 taatgcagag gcgattgcag aagaattggg agcaaaagta gcaagttcct tagatgagtt
     6661 ggtttctagc gatgaagtag attgtgttat cgtcgcaact ccaaataatc ttcataagga
     6721 accggttatt aaggctgcac agcatggtaa aaatgttttc tgtgaaaaac caattgcgct
     6781 ttcttatcaa gattgtcgcg agatggtaga tgcgtgtaaa gaaaacaatg taacctttat
     6841 ggcaggacat attatgaatt tctttaatgg tgttcatcat gcaaaagaac tcattaatca
     6901 aggagttatc ggagacgttc tatattgtca tacagctcgt aatggttggg aagaacaaca
     6961 accgtcagta tcatggaaaa aaattcgtga aaaatcaggt ggtcacttgt atcaccacat
     7021 ccatgaattg gattgcgttc aattccttat ggggggcatg cctgaaactg taaccatgac
     7081 aggtggaaat gtggcccatg aaggtgaaca tttcggtgat gaagatgata tgatttttgt
     7141 caatatggaa ttttctaata agcgttttgc cttgttagaa tggggttcag cttatcgttg
     7201 gggtgaacat tatgtcttaa tccaaggaag caaaggtgcc atccgcttag acttattcaa
     7261 ctgtaaagga actcttaagc tagatgggca agaaagctat ttcttgattc acgaatcgca
     7321 agaagaagat gatgatcgga ctcgtatcta tcatagtaca gagatggatg gagcaattgc
     7381 ttatggtaaa ccaggtaaac gtactccatt atggctatca tctgtcattg ataaagaaat
     7441 gcgctatctg catgagatta tggaaggagc tccagtatca gaagaatttg caaaactttt
     7501 gacaggtgaa gctgccctag aagcaattgc tactgcagat gcttgtaccc agtctatgtt
     7561 tgaagatcgc aaagtaaaat tgtcagaaat tgtaaaataa attttggtat tctcctattt
     7621 ataggtcgac ttgctcctct gaaagtactt ttagaggagc tgtttgactt tgctagtttt
     7681 tgaaactgaa atctattata ctacaaacta ttgaaagcgt tttaatttta aggtataata
     7741 atctcataga aataaagaaa aggaggaaag aggatgccac agattagcaa agaagccttg
     7801 attgagcaaa tcaaagatgg aatcatcgtt tcttgtcagg ctcttcctca tgaaccgctt
     7861 tatacagaag cgggaggggt gattcccttg ctggtcaaag cggctgagca aggtggagca
     7921 gtcggtatcc gagcaaacag tgttcgcgat atcaaggaaa ttaaggaagt cactaaactt
     7981 ccaatcattg ggattatcaa acgtgattat ccacctcagg aacccttcat cacggctact
     8041 atgaaagaag ttgatgaatt ggcagaactg gacatcgagg tgattgctct ggattgtacc
     8101 aagcgtgaac gctacgatgg tttggaaatt caagagttca ttcgtcaggt taaggagaaa
     8161 tatcctaatc agcttttgat ggctgatact agtatcttcg aagaagggct agcagctgta
     8221 gaagcaggaa ttgactttgt cggaacaacc ttatcaggct acacatccta cagtccaaaa
     8281 gtagacggtc cagattttga attgattaag aaactctgtg atgctggtgt agatgtcatt
     8341 gcagaaggaa aaattcatac accagaacaa gccaaacaaa tccttgaata tggagtgcga
     8401 ggcatcgttg ttggtggcgc cattactaga ccaaaagaga ttacagaacg cttcgttgct
     8461 agtcttaaat aagatgtgag ggggagtttt atgtttaaag ttttacaaaa agttggaaaa
     8521 gcttttatgt tacctatagc tatacttcct gcagcaggtc tacttttggg gattggtggt
     8581 gcactttcaa acccaaccac gatagcaact tatccaatac tagacaatag tatttttcaa
     8641 tcaatattcc aagtaatgag ctctgcagga gaggttgtat tcagtaattt gtcactactt
     8701 ctctgtgtgg gattatgtat tggcttagcg aaacgagata aaggaaccgc tgcgttagca
     8761 ggagtaactg gttacttagt tatgactgca acgatcaaag ctttggtaaa actttttatg
     8821 gcagaaggat ctgcaattga tactggagtt attggagcat tagttgtcgg aatagttgcc
     8881 gtatatttgc acaaccgata taacaatatt caattacctt ccgctttagg attctttgga
     8941 ggttcacgct tcgttcctat tgttacatcg ttctcttcta tcttgattgg ctttgtcttc
     9001 tttgttattt ggccaccttt ccaacaactt cttgtttcta caggtggata tatttctcag
     9061 gcgggtccaa ttggaacttt tctatatgga tttttaatga gactttctgg agcagtaggc
     9121 ttacatcata taatttaccc tatgttttgg tatactgaac ttggtggtgt tgaaactgtt
     9181 gcaggacaaa cagtggttgg agctcaaaaa atattttttg ctcaattagc cgatttggcc
     9241 cattctggat tatttacaga aggaacaagg ttttttgcag gtcgtttctc aacaatgatg
     9301 ttcggtttac cggctgcctg tttagcgatg taccatagtg ttcctaaaaa tcgtcgtaaa
     9361 aaatacgcgg gtttgttttt tggagttgct ttaacatctt ttattaccgg tattacagaa
     9421 ccaattgaat ttatgtttct attcgtcagt ccggttctat atgttgttca cgcattcctt
     9481 gatggtgtta gcttctttat tgcagacgtc ttaaatattt caataggaaa cacattttca
     9541 ggaggtgtaa tcgatttcac tttatttgga attttgcagg ggaacgctaa gacgaattgg
     9601 gttcttcaga ttccatttgg acttatttgg agtgttttgt attatattat ttttagatgg
     9661 ttcattactc aattcaacgt tctaacgcca gggcgaggag aagaagtaga ttctaaagaa
     9721 atttctgaat ccgcagattc aacttcaaat actgcagatt atttaaaaca ggatagccta
     9781 caaattatca gagccttggg tggatcaaat aatatagaag atgtagatgc ttgtgtgaca
     9841 cgtttacgtg tagctgtaaa agaagttaat caagttgata aagcactttt aaaacaaatt
     9901 ggtgcagttg atgtcttaga agtgaagggt ggcattcaag caatctatgg agcaaaagca
     9961 atcttatata aaaatagtat taatgaaatt ttaggtgtag atgattaagt acttactgac
    10021 ttaataaaaa acagaggaga gtgatggatg agtaggatga aatgaaatcg catacaagaa
    10081 ataaagaact cattatccaa gttggatacg cttattacat aggagaatac aaatgaaatt
    10141 tagaaaatta gcttgtacag tacttgcggg tgctgcggtt cttggtcttg ctgcttgtgg
    10201 caattctggc ggaagtaaag atgctgccaa atcaggtggt gacggtgcca aaacagaaat
    10261 cacttggtgg gcattcccag tatttaccca agaaaaaact ggtgacggtg ttggaactta
    10321 tgaaaaatca atcatcgaag cgtttgaaaa agcaaaccca gatataaaag tgaaattgga
    10381 aaccatcgac ttcaagtcag gtcctgaaaa aatcacaaca gccatcgaag caggaacagc
    10441 tccagacgta ctctttgatg caccaggacg tatcatccaa tacggtaaaa acggtaaatt
    10501 ggctgagttg aatgacctct tcacagatga atttgttaaa gatgtcaaca atgaaaacat
    10561 cgtacaagca agtaaagctg gagacaaggc ttatatgtat ccgattagtt ctgccccatt
    10621 ctacatggca atgaacaaga aaatgttaga agatgctgga gtagcaaacc ttgtaaaaga
    10681 aggttggaca actgatgatt ttgaaaaagt attgaaagca cttaaagaca agggttacac
    10741 accaggttca ttgttcagtt ctggtcaagg gggagaccaa ggaacacgtg cctttatctc
    10801 taacctttat agcggttctg taacagatga aaaagttagc aaatatacaa ctgatgatcc
    10861 taaattcgtc aaaggtcttg aaaaagcaac tagctggatt aaagacaatt tgatcaataa
    10921 tggttcacaa tttgacggtg gggcagatat ccaaaacttt gccaacggtc aaacatctta
    10981 cacaatcctt tgggcaccag ctcaaaatgg tatccaagct aaacttttag aagcaagtaa
    11041 ggtagaagtg gtagaagtac cattcccatc agacgaaggt aagccagctc ttgagtacct
    11101 tgtaaacggg tttgcagtat tcaacaataa agacgacaag aaagtcgctg catctaagaa
    11161 attcatccag tttatcgcag atgacaagga gtggggacct aaagacgtag ttcgtacagg
    11221 tgctttccca gtccgtactt catttggaaa actttatgaa gacaaacgca tggaaacaat
    11281 cagcggctgg actcaatact actcaccata ctacaacact attgatggat ttgctgaaat
    11341 gagaacactt tggttcccaa tgttgcaatc tgtatcaaat ggtgacgaaa aaccagcaga
    11401 tgctttgaaa gccttcactg aaaaagcgaa cgaaacaatc aaaaaagcta tgaaacaata
    11461 gtccttagtt attctataaa aagtagtttt ttaaagaacc taagagtgta tacccccttt
    11521 tccctctaca cagatagtgt aagaaaaggg ggcttttgtt taaaatgtaa gaaactgtca
    11581 cgaaattaaa atgaagttct tacataagcg aatcataaaa aatttcattt tgattttaaa
    11641 acagttcaag aaagtcaaaa aattattcta tttgaaagag aggtgccgac tgtgaaagtc
    11701 aataaaatcc gtatgcggga aacagtgatt tcctacgctt tcctagcacc agtattattc
    11761 ttctttgtca tctttgtgtt ggctccgatg gtgatgggct tcattacaag tttctttaac
    11821 tactcaatga ctaaatttga gtttgtaggc ttggataact atatccgtat gtttaaagat
    11881 cctgtcttta caaaatctct gattaacaca gttattttgg ttattggatc tgtaccagtt
    11941 gttgttctat tctcactctt tgtagcatct cagacctatc atcaaaatgt cattgccaga
    12001 tccttctacc gtttcgtctt cttccttcct gttgtaacgg gtagtgttgc cgtgacagtt
    12061 gtttggaaat ggatttatga cccactatca gggattctaa actttgtcct taagtccagc
    12121 cacatcatca gccaaaacat ttcttggttg ggagataaaa actgggcatt gatggcgatt
    12181 atgattattc tcttgaccac ttcagttggt cagcccatca tcctttatat cgctgccatg
    12241 gggaatattg acaattcact ggttgaagcg gcgcgtgttg atggtgcaac tgagtttcaa
    12301 gttttttgga agattaaatg gccaagcctt cttccaacaa ctctttatat tgcaatcatc
    12361 acaacaatta actcattcca gtgtttcgcc ttgattcagc ttttgacatc tggtggtcca
    12421 aactactcaa caagtacctt gatgtactac ctttacgaaa aagccttcca attgacagaa
    12481 tacggctatg ccaacacaat tggtgtcttc ttggcagtca tgattgctat cgtaagcttt
    12541 gttcaattta aagtacttgg aaacgacgta gaatactaaa gaaaggagac agctatgcaa
    12601 tctacagaaa aaaaaccatt aacagccttt actgttattt caacaatcat tttgctcttg
    12661 ttgactgtgc tgttcatctt tccattctac tggattttga caggggcatt caaatcacaa
    12721 cctgatacaa ttgttattcc tcctcagtgg ttccctaaaa tgccaaccat ggaaaacttc
    12781 caacaactca tggtgcagaa ccctgccttg caatggatgt ggaactcagt atttatctca
    12841 ttggtaacca tgttcttagt ttgtgcaacc tcatctctag caggttatgt attggctaaa
    12901 aaacgtttct atggtcaacg cattctattt gctatcttta tcgctgctat ggcgcttcca
    12961 aaacaagttg tccttgtacc attggtacgt atcgtcaact tcatgggaat ccatgatact
    13021 ctctgggcag ttatcttgcc tttgattgga tggccattcg gtgtcttcct catgaaacag
    13081 ttcagtgaaa atatccctac agagttgctt gaatcagcta aaatcgacgg ttgtggtgag
    13141 attcgtacct tctggagtgt agccttcccg attgtgaaac cagggtttgc agcccttgca
    13201 atctttacct tcatcaatac ttggaatgac tacttcatgc aattggtaat gttgacttca
    13261 cgtaacaatt tgaccatctc acttggggtt gcgaccatgc aggctgaaat ggcaaccaac
    13321 tatggtttga ttatggcagg agctgccctt gctgctgttc caatcgtcac agtcttccta
    13381 gtcttccaaa aatccttcac acagggtatt actatgggag cggtcaaagg ataatactct
    13441 gcgaaaatct cttcaaacta cgtcagcttc accttgccat acttaagtat tgcctgcggt
    13501 tagcttccta gtttgttctt caattttcat tgagtatagg aaaatcaatc tatcaagata
    13561 cagaagtata ttttatagat ttagagaata tagaggttat aagtgtctac aaaatggagg
    13621 gtatgcagtt actttatgaa gttttgtcag acacttataa acttaagaat ggttttagtt
    13681 aactatcaga aacgaaggaa agagtatgat ttttgacgat ttgaaaaaca tcacctttta
    13741 caaagggatt catcctaatt tagacaaggc tatcgactat ctctaccaac atcgtaagga
    13801 ttctttcgaa ttaggaaagt atgatattga tggagataaa gtctttctag ttgttcagga
    13861 aaatgtcctc aatcaagctg aaaatgatca atttgagtat cataagaact atgcagattt
    13921 gcatttgctg gtagaaggac atgaatattc gagctacggt tcacgtatca aagacgaggc
    13981 agtagcattc gacgaagcga gtgacattgg ctttgttcat tgtcatgaac actacccact
    14041 cttgttgggt tatcacaatt ttgcgatttt cttcccaggt gagccacatc agccaaatgg
    14101 ttatgcaggc atggaagaaa aggttcgaaa atatctcttt aaaattttga ttgattaaaa
    14161 ataggatgaa ttgttttttt gtaaagcttt gataatactc taccatgaaa ttgatctttg
    14221 tgaggtagag aaatgagaat aaaatattta aaaattggta tcttctaagt atgctgcaag
    14281 agctagtttc ttagatggac aggggattac agttgatgag atggcttgga taattagggg
    14341 cattgtgaat gcattgattg gtagatacat aaaattaggt acttatgcgg ctaagtatgg
    14401 tattagtatg gcacgctcga tcttaagtag ggtagctgca actgcagcag caagagtagg
    14461 attactgacc aagatttctg gatggatttt acgagtagct gtgaatgtag ctgatgtata
    14521 tggtaatttt gccaacaata ttgctgcagc ttgggatgca tatgataaaa ttcctaacaa
    14581 tggtcgtata aacttttaaa atgcgagaat gaaagcactt tgtatttttt tattgaatat
    14641 gttagcttgg acagtgcttg caatgataat tcgtggaggg ctagatggat ttgataggca
    14701 tacttggagt actattttaa ttgcttcgct gttcggggta tatgattata agcccataga
    14761 taaaaataga aaaaagtcca aaagaaaaaa tagatttgtt catggtaggg acttatgaaa
    14821 gctttactga caaaaaagaa aacagtttac aaagaaaaat gatggaggag caaacatggc
    14881 acaaaaagga gtaagcctta tcaaggcagc atttgataca gataactttc tcatgcgttt
    14941 tagtgagaag gtcttggaca tcgtgacagc caatcttctt tttgtcgtct cttgtttacc
    15001 catcgtgacg attggagtgg ctaaaatcag cctctacgag accatgttcg aagttaagaa
    15061 gagcagacgg gtgcctgttt ttaaaatcta tctaagatct ttcaagcaaa atctgaaact
    15121 aggtcttcag ctgggtttaa tggagttagg aattgtgttt cttacccttt cagatctcta
    15181 tcttttctgg ggtcaaacag ctctgccctt ccaattgctg aaagccattt gtttaggtat
    15241 tctgattttt cttactatcg tgatgctggc tagttaccct atcgcggcac gttatgacct
    15301 atcttggaaa gaaattcttc aaaaaggatt gatgttggct agttttaact ttccttggtt
    15361 cttcctcatg ttagccattc ttgtcctcat tgtgatggtt ctttatctgt ccgccttcag
    15421 tctactctta ggtggctcag tcttcctact ttttgggttt ggactattgg tctttatcca
    15481 gactggattg atggagaaaa ttttcgcaaa ataccaatag gagctttatt tctgaaacta
    15541 ctttcaaagg ctccaaacgc tattctataa gcgagaaact aaaatctaag tgtctataag
    15601 atattgaaag ccttttcggt aaagtgtata ctaaagaagt aaagaaaaat ctgctttagc
    15661 agaaaataaa aataatagga gaaaatctat gtcagatttg aaaaaatacg aaggtgtcat
    15721 tccagccttc tacgcatgtt atgatgatca aggagaagta agcccagaac gtacgcgtgc
    15781 cttggttcaa tacttcattg ataaaggtgt tcaaggtctt tatgtcaatg gttcttctgg
    15841 tgaatgtatc taccaaagcg ttgaagatcg caagttgatt ttggaagaag tcatggcggt
    15901 agccaaaggt aaattgacca ttattgctca tgttgcctgc aacaatacta aagacagtat
    15961 ggaacttgct cgccatgctg aaagcttggg agtagatgct attgcaacga ttccaccaat
    16021 ttatttccgc ttgccagaat actcagttgc caaatactgg aacgatatca gttctgcagc
    16081 tccaaacaca gactacgtga tttacaacat tcctcaattg gcaggggttg ctttgactcc
    16141 aagcctttac acagaaatgt tgaaaaatcc tcgtgttatc ggtgttaaga actcttctat
    16201 gccagttcaa gatatccaaa cctttgtcag ccttggtggg gaagaccata tcgtctttaa
    16261 tggtcctgat gagcagttcc taggaggacg cctcatgggt gctagggctg gtatcggtgg
    16321 tacttatggt gctatgccag aactcttctt gaaactcaat cagttgattg cggataagga
    16381 cctagaaaca gcgcgtgaat tgcagtatgc tatcaacgca atcattggta aactcacttc
    16441 tgctcatgga aatatgtacg gtgtcattaa agaagtcttg aaaatcaatg aagtcttgaa
    16501 tattggatct gttcgttcac cattgacacc agtgactgaa gaagatcgtc cagttgtaga
    16561 agcggctgct gccttgattc gtgaaaccaa ggagcgcttc ctctaatcta aaaggaggta
    16621 tttatgacat attacgttgc aattgatatc ggtggaacca acatcaagta tggtttggtt
    16681 gatcaagagg ggcaacttct tgaatcgcat gaaatgccaa ctgaggcgca taagggtgga
    16741 cctcatatct tacaaaagac caaagatatc gtagctagtt atttagaaaa aggcccagta
    16801 gcaggtgttg ccatatcttc tgctgggatg gtggatccgg ataagggtga gattttctat
    16861 gctgggccgc aaatccctaa ctacgcaggc acccagttca aaaaggaaat cgaagaaagc
    16921 tttactattc cttgtgagat tgaaaatgat gtcaactgtg caggtcttgc tgaggcagta
    16981 tctggttcag gcaagggagc aagtgtgaca ctttgcttga ccattggaac cggtatcggt
    17041 ggttgcttga ttatggatag gaaagtcttc catggtttta gcaattcagc ctgtgaagtc
    17101 gggtatatgc atatgcagga tggagctttt caagacttgg cttctacaac agctttagtg
    17161 aaatatgtag ctgaagccca tggagaagat gttgatcagt ggaatggccg tagaattttc
    17221 aaagaagcca ctgaaggaaa caaaatctgc atggaaggta ttgaccgtat ggttgactat
    17281 ctaggaaaag gtctggcaaa tatttgctac gttgccaatc cagaagtggt tattcttggt
    17341 ggtggtatca tggggcaaga ggctatcctc aaacctaaga tccgtacagc cttgaaagag
    17401 gctttggtac caagtttagc agaaaaaaca cgattagaat ttgcccatca ccaaaataca
    17461 gcagggatgt tgggtgcata ttatcatttt aagacaaaac aatcctagtt tggctcagcc
    17521 aaactaggat tttcttacac gtttttgtct acgatagccg ttgagttttt tattttccca
    17581 gtagctatta aagatttttt ccttgctttc gcgattgatt tccaaaaagt aggcataaat
    17641 caaatcgata aagaagagca taggaagttg agcggatatt cgttggatat aggagggttg
    17701 gctgtgggtg gctacaagaa cagtctctgt ataggtctgg ctatctttat tgggaacact
    17761 tgtaaagagt acagtctttg cccccatctc cttagcatct aatagactat ctaaaataga
    17821 aggagttgag cctgaaagtg agaagcccag tactagacaa ttttcatcca tgatgctggt
    17881 tgtccaggca aagccgtctt ggtctgtcaa agcttcgcag accacaccta gtcgcataaa
    17941 acgtaatttc atttcacggg cgacgaggcc agaactccct gttccaaaga agtagatacg
    18001 ctcagcatct tcgattagct gggcaattcg ttctagttgg atttcgtcaa tcaagtcttg
    18061 tgtttgttcc ctcatattgc tataacttct gaggactcgt ttggtcagtg gactgtgctt
    18121 ggagacttgg ttggcttgat tttctgcctg atgttggtat tggaaaataa attctcggta
    18181 gccagtaaag ccacactttt tagcaaagcg ggtcaaagca gcttgagaaa tatgtaattt
    18241 ttgggtgact tgttgagaag ataaatcatc tgtaatcgtt tcagcttgca aaaaatagcg
    18301 agcgatttct tgttctaggt ctgtcatttc ttcaaaatgt gaatcaatga tagttgcgat
    18361 atctggtttg tccataggga aagctccttt acatgagtca tactggaaga ctagatcaga
    18421 gaatagtcac acttcattat aacacataat ataaggatag ataaataaaa acgcatctct
    18481 gttttaaaaa cgaaaaaatc gaaaaagctt ctctcttttc cataattttc tactcaaatt
    18541 gtggtacaat taagagtaag attttaagtt agaaatgaga ctgatttgta tgagaaaatt
    18601 taacagccat tcgattccga ttcggcttaa tttattgttt tcaatcgtca ttttactctt
    18661 tatgaccatt attggtcgtt tgttgtatat gcaggttttg aacaaggatt tttacgaaaa
    18721 aaagctagct tcagctagtc agaccaagat tacaagcagt tcagcccgtg gggaaattta
    18781 tgatgctagt ggaaaacctt tggtagaaaa tacgttaaag caggttgttt cctttacgcg
    18841 tagcaataaa atgacggcta cagacttaaa agaaacagct aaaaagttac tgacttatgt
    18901 gagcatcagt tctccaaatt tgacagaacg ccagctggcg gattactatt tggctgatcc
    18961 tgaaatctat aaaaaaatag tggaagctct cccaagtgag aaacgcttgg attcagatgg
    19021 caatcgtcta tccgaatcag aactgtataa caatgcggtc gatagtgtac aaacgagtca
    19081 actaaactat acagaggatg aaaagaaaga aatctatctt tttagtcagt taaatgctgt
    19141 tggaaacttt gcgacaggaa ccattgcgac agatcctcta aatgattctc aggtggctgt
    19201 tattgcctct atttcaaagg agatgcctgg cattagtatt tctacttctt gggatagaaa
    19261 ggttttggaa acttcccttt cttctatagt tgggagtgta tccagtgaaa aagctggtct
    19321 cccagcggaa gaagcagaag cctatcttaa aaaaggctat tctctaaatg accgtgtagg
    19381 aacctcctat ttggaaaagc aatatgaaga gaccttacaa ggaaaacgct cggtaaaaga
    19441 aatccatctg gataaatatg gcaatatgga aagcgtggat acaattgagg aaggtagtaa
    19501 gggaaacaat atcaaactga ccattgattt ggctttccaa gatagcgtgg atgctttact
    19561 gaaaagttat ttcaattctg agctagaaaa tggtggagcc aagtattctg aaggtgtcta
    19621 tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct atgtcaggga ttaaacatga
    19681 cttgaaaacg ggagagttga cgcctgattc cttgggaacg gtaaccaatg tctttgttcc
    19741 aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg gaaaatggag tcttgtcagg
    19801 aaaccagacc ttgacagacc agtccattgt cttccaaggt tcagctccca tcaattcttg
    19861 gtatactcag gcttacggtt cattccctat cacagcggtc caagctctgg agtattcatc
    19921 aaatacctat atggtccaaa cagccttagg tcttatgggg caaacctatc aacccaatat
    19981 gtttgtcggc accagcaatc tagagtctgc tatggagaaa ctgcgttcaa cctttggcga
    20041 atatggcttg ggtactgcga caggaattga cctaccagat gaatctactg gatttgttcc
    20101 caaagagtat agctttgcta attacattac taatgccttt gggcagtttg ataactatac
    20161 gccgatgcag ttggctcagt atgtagcaac tattgcaaat aatggtgttc gtgtggctcc
    20221 tcgtattgtt gaaggcattt atggtaataa tgataaggga ggactgggtg acttgattca
    20281 gcaactgcaa ccgacagaga tgaataaggt caatatatcc gactccgata tgagcatctt
    20341 gcaccaaggt ttttatcagg ttgcccatgg tactagtgga ttgacaactg gacgtgcctt
    20401 ttcaaatggt gccttggtat ccattagcgg aaaaacaggt acagccgaaa gctatgtggc
    20461 agatggtcag caagcaacca ataccaatgc ggtggcctat gccccatctg ataatcccca
    20521 aatcgctgtc gcagtggtct ttcctcataa taccaatcta acaaatggtg taggaccttc
    20581 cattgcgcgt gacattatca atctgtatca aaaataccat ccaatgaatt agaaaggaaa
    20641 ttatgcttta tccaacacct attgccaagt tgattgacag ttattctaag ttaccaggta
    20701 tcgggattaa gacggctacg cgtctggcct tttatacgat tgggatgtct gctgatgatg
    20761 tcaatgaatt tgcaaaaaat ctcctttctg ctaagagaga attgacatat tgttctattt
    20821 gtggacgttt gacagacgac gatccttgtt ctatctgtac tgatccgact cgtgaccaga
    20881 caacaatttt agttcttgag gatagtagag atgtggcagc catggaaaat atccaagaat
    20941 accatggact ctatcatgtc cttcatggcc tcatttctcc tatgaatggt atcagtccgg
    21001 acgatatcaa tctcaagagc cttatgactc gtcttatgga tagtgaggtt tcagaagtga
    21061 ttgtggcgac taatgctaca gcggatggtg aagcgacttc catgtatctt tcacgtttgc
    21121 tcaagccggc tggtatcaag gttacgcgtc tagcacgagg tctcgctgtg ggagcggaca
    21181 ttgagtatgc ggacgaagtg acactcttac gagccattga aaatcggaca gagttgtaag
    21241 tgtaggcaaa tttacgaact ccattcattt ataaaaaatc aaagaggctg aaaatcgttc
    21301 ctatcggcct ctttttgtat agtgtgatga gtaggctcag gttcaagttt taaaaaacca
    21361 agcaaatatg atatactaaa gagcgagtat tctagtagaa ttaggacaaa taatatgaaa
    21421 caaacgatta ttcttttata tggtggacgg agtgcggaac gcgaagtctc tgtcctttca
    21481 gctgagagtg tcatgcgtgc ggtcgattac gaccgtttca cagtcaagac tttctttatc
    21541 agtcagtcag gtgactttat caaaacacag gaatttagtc atgctccggg gcaagaagac
    21601 cgtctcatga ccaatgaaac cattgattgg gataagaaag ttgcaccaag tgctatctac
    21661 gaagaaggtg cagtggtctt tccagtcctt cacgggccaa tgggagaaga tggctctgtt
    21721 caaggattct tggaagtttt gaaaatgcct tacgttggtt gcaacatttt gtcatcaagt
    21781 cttgccatgg ataaaatcac gactaagcgt gttctggaat ctgctggtat tgcccaagtt
    21841 ccttatgtgg ctatcgttga aggcgatgat gtgactgcta aaatcgctga agtggaagaa
    21901 aaattggctt atccagtctt cactaagccg tcaaacatgg ggtctagtgt cggtatttct
    21961 aagtctgaaa accaagaaga actccgtcaa gccttaaaac ttgccttccg atatgacagc
    22021 cgtgtcttgg ttgagcaagg agtgaatgcc cgtgaaattg aggttggcct cttgggtaac
    22081 tacgatgtca agagcacgct accaggagaa gttgtcaagg acgttgcctt ttatgactac
    22141 gatgccaagt atattgataa caatattact atggatattc ctgccaaaat cagtgatgat
    22201 gtggtggctg tcatgcgtca aaatgcagaa acagccttcc gtgccattgg tggccttggt
    22261 ctatctcgtt gcgatttctt ctatacagat aagggagaga tttttctcaa cgagctcaat
    22321 actatgccag gtttcaccca gtggtctatg tacccactac tttgggacaa tatggggatc
    22381 agctacccaa aactaatcga gcgtttggtt gaccttgcca aggaaagttt tgacaagcgc
    22441 gaagcgcatt tgatataaaa tgaaagagag ggtagaagcc agaaccatca ctgcacggtg
    22501 actagagttc tcggacttca gcccttttta aaggagtaga aatgaaatta acaatccatg
    22561 aaattgccca agttgttgga gccaaaaatg atatcagtat ctttgaggac acccagttag
    22621 aaaaagctga gtttgatagt cgtttgattg gaactggaga tttatttgtg ccacttaaag
    22681 gtgcgcgtga tggccatgac tttattgaaa cagcctttga aaatggtgca gcagtaacct
    22741 tgtctgagaa agaggtctca aatcatcctt acattctagt agatgatgtt ttgacagcct
    22801 ttcaatcctt agcatcctac tatcttgaaa aaacgactgt tgatgtcttt gctgttacag
    22861 gttcaaatgg caagacaacg actaaggata tgttggcgca tttactgtca acaagataca
    22921 agacctacaa aacacaaggc aattacaata atgagattgg ccttccttac acagttcttc
    22981 atatgcctga aggaacagaa aagttggttt tggagatggg acaggatcac ttgggcgata
    23041 ttcatctctt gtctgaattg gctcgtccaa aaacagccat cgtgaccttg gttggagaag
    23101 cccatttggc ctttttcaaa gaccgttcag agattgctaa gggaaaaatg caaattgcag
    23161 acggaatggc ttcaggttcc ttgcttttag cgccggctga ccctatcgta gaggactatt
    23221 tgccaactga taaaaaggtg gttcgttttg ggcaaggggc agagctggaa attactgact
    23281 tggttgagcg caaagatagt ctgaccttca aggccaattt cttagagcaa gcccttgatt
    23341 tgccagtaac tggcaagtac aatgcgacaa atgctatgat tgcatcctat gttgccttgc
    23401 aagaaggagt ttcagaggag caaattcgtt tggccttcca agatcttgaa ttgacgcgta
    23461 accgtaccga gtggaagaaa gcagccaatg gagcagatat cctgtcagat gtttacaatg
    23521 ccaatccaac tgctatgaaa ctgattttag agactttctc tgccattcca gccaatgaag
    23581 gtggcaagaa aattgcagtg ttggcggata tgaaggagct tggtgaccag tctgttcaac
    23641 ttcataatca gatgattttg agcctttctc cagatgtgct tgataccgtg attttctatg
    23701 gacaagatat tgctcagttg gttcaattgg ccagtcaaat gttcccaatc ggccacgttt
    23761 actacttcaa gaaaacagaa gaccaggatc aatttgaaga cctagtcaag caggtcaagg
    23821 aaagccttgg agcccatgac caaatcctgc tcaaaggctc taactctatg aatctagcca
    23881 agttggtaga aagtttagaa aatgaagaca agtgattttg tcaagtattt gcaaagaatg
    23941 attgccatta cagatactgg cttaaccttt acaaaagatc cgtttgaccg tgagcgctac
    24001 gaagacttgc gaagtctgtt atctgaaatg ttgaatcaag catcagacct tgattccgaa
    24061 gaagtggcag aagtcttgaa gccaacttct gcttatgcga ctccgttaat ggacgtccgt
    24121 gcttggattg ttgaggatga gaagatttgt ctggttaggg gacaaggaga ggatagttgg
    24181 gctttgccag gtggctttgg tgaagtcggc tattctccaa cagaaaatat tctcaaggaa
    24241 attgaagaag aaaccggttt taaagccaaa gttgaaagac tgctagctgt ttttgatacc
    24301 aatcgtttcc aactacagag caaacagtat acaaagtttg tttttggatg taagcttctt
    24361 gatggacaat tccaagaaaa tcaagaaatt gctgaccttc aattttttgc cattgaccaa
    24421 ctgccgaact tatctgaaaa acgcattacc aaggagcaaa tagagcttct ttggcaggtt
    24481 tatcaaggtc atagggggca atatcttgac taagaagatg attatcgtat ttctaaatcc
    24541 atttttaaca actagcatgg tataataata tgcaggaaaa ttttgaatta tgaggaagac
    24601 tagatgaatt tatgggatat tttctttacg actcaggcaa ccgagccgcc caaatttgac
    24661 cttttttggt atgttagcct atttacgctc ttagccttaa ccttttatac agcccatcgc
    24721 tatcgtgaaa agaaggttta ccaacgattt ttccaaatct tgcagactgt tcagttaatc
    24781 cttctttatg gttggtactg ggtcaatcat atgccactgt cagaaagcct acccttttac
    24841 cattgccgta tggctatgtt tgtggtactc ttgcttcctg gtcaatccaa atataaacaa
    24901 tactttgcat tattgggaac atttgggaca ttagcagcct ttgtttatcc agtgccagat
    24961 gcttaccctt ttccacatat caccattcta tcctttatct ttggtcattt agcactcttg
    25021 gggaactctc tagtttatct attgagacag tataatgcgc gattgctgga tgtgaaggga
    25081 atttttctca tgacctttgc cctaaatgcc ttgatttttg tggtcaattt agtgacaggt
    25141 ggcgattacg gatttttgac aaaaccgcca ttggttgggg atcacggtct agtagctaat
    25201 tatttacttg tttcaattgt gctggtagct actatcagtt tgactaagaa aatcttagaa
    25261 ttctttttag ctcaagaagc agaaaaaatg attgcaaagg aagcttaaca cagagctttc
    25321 ttttttgctc ttagagagtt tttacaagca gcttataaaa taagaatttc tgaatagaca
    25381 aactcaaaaa atggctggga aatttaggaa aaaagcaagc acgattaaat tttttgtgtt
    25441 ataatatttt gtgaatagct atgcctatgt ttagctatgg aataatacga agtgcgaaac
    25501 ttggaagata gagaggaagc gatgtaatgg ctagagaagg cttttttaca ggtctagata
    25561 ttggaacaag ctctgtcaag gtgcttgtgg ccgagcagag aaatggtgaa ttaaatgtaa
    25621 ttggcgtgag taatgccaaa agtaaaggtg taaaggatgg aattattgtt gatattgatg
    25681 cagcagcaac tgctatcaag tcagccattt cccaagcgga agaaaaggca ggcatttcga
    25741 ttaaatcagt gaatgtcggc ttgcctggta atcttttgca ggtagaacca actcagggga
    25801 tgattccagt aacatctgat actaaggaaa ttacggatca agatgttgaa aatgttgtca
    25861 aatcagcttt gacaaagagt atgacacctg accgtgaagt cattaccttt attcctgaag
    25921 aatttattgt ggatggtttc caagggattc gtgacccacg tggcatgatg ggggttcgcc
    25981 ttgaaatgcg tggtttgctt tatacaggac ctcgtactat cttgcacaat ttgcgtaaga
    26041 cggttgagcg tgcaggtgtt caggttgaaa atgttatcat ttcaccacta gcaatggttc
    26101 agtctgtttt gaatgaaggg gaacgtgaat ttggtgctac agtgattgat atgggggcag
    26161 gtcaaacgac tgtcgctaca atccgtaatc aagaactcca gttcacacat attctccaag
    26221 aaggtggaga ttatgtaact aaagatatct ccaaggtttt gaaaacctct cgcaaattag
    26281 cggaaggctt gaaactgaat tacggggaag cctatccgcc tcttgcaagc aaagaaacct
    26341 tccaagtaga ggttattgga gaagtggaag cagtcgaagt gacggaagcc tacttgtcag
    26401 aaattatttc tgcacgaatc aagcacatcc ttgaacaaat caagcaagaa ttagatagaa
    26461 ggcgtctatt ggacctccct ggtggtattg tcttaatcgg tgggaatgcc attttaccag
    26521 gtatggttga gcttgctcag gaagtctttg gcgtccgtgt caagctttat gttccaaatc
    26581 aagttggtat ccgtaatcca gcctttgcgc atgtgattag tttatcagaa tttgcgggtc
    26641 aattaacaga agttaatctt ttggctcagg gagcgataaa aggtgagaat gacttaagtc
    26701 atcagccaat tagttttggt gggatgctgc aaaaaacagc tcagtttgta caatcaacgc
    26761 ctgttcaacc agctcctgct ccagaagtag agccggtggc gcctacagaa ccaatggcgg
    26821 atttccaaca agcttcacaa aataaaccga aattagcaga tcgtttccgt ggcttgatcg
    26881 gaagcatgtt tgacgaataa agaggaaaaa taaattatga cattttcatt tgatacagct
    26941 gctgctcaag gggcagtgat taaagtaatt ggtgtcggtg gaggtggtgg caatgccatc
    27001 aaccgtatgg tcgacgaagg tgttacaggc gtagaattta tcgcagcaaa cacagatgta
    27061 caagcattga gtagtacaaa agctgagact gttattcagt tgggacctaa attgactcgt
    27121 ggtttgggtg caggaggtca acctgaggtt ggtcgtaaag ccgctgaaga aagcgaagaa
    27181 acactgacgg aagctattag tggtgccgat atggtcttca tcactgctgg tatgggagga
    27241 ggctctggaa ctggagctgc tcctgttatt gctcgtattg ccaaagattt aggtgcgctt
    27301 acagttggtg ttgtaacacg tccctttggt tttgaaggaa gtaagcgtgg acaatttgct
    27361 gtagaaggaa tcaatcaact tcgtgagcat gtagacactc tattgattat ctcaaacaac
    27421 aatttgcttg aaattgttga taagaaaaca ccgcttttgg aggctcttag cgaagcggat
    27481 aacgttcttc gtcaaggtgt tcaagggatt accgatttga ttaccaatcc aggattgatt
    27541 aaccttgact ttgccgatgt gaaaacggta atggcaaaca aagggaatgc tcttatgggt
    27601 attggtatcg gtagtggaga agaacgtgtg gtagaagcgg cacgtaaggc aatctattca
    27661 ccacttcttg aaacaactat tgacggtgct gaggatgtta tcgtcaacgt tactggtggt
    27721 cttgacttaa ccttgattga ggcagaagag gcttcacaaa ttgtgaacca ggcagcaggt
    27781 caaggagtga acatctggct cggtacttca attgatgaaa gtatgcgtga tgaaattcgt
    27841 gtaacagttg ttgcaacggg tgttcgtcaa gaccgcgtag aaaaggttgt ggctccacaa
    27901 gctagatctg ctactaacta ccgtgagaca gtgaaaccag ctcattcaca tggctttgat
    27961 cgtcattttg atatggcaga aacagctgaa ttgccaaaac aaaatccacg tcgtttggaa
    28021 ccaactcagg catctgcttt tggtgattgg gatcttcgcc gtgaatcgat tgttcgtaca
    28081 acagattcag tcgtttctcc agtcgagcgc tttgaagccc caatttcaca agatgaagat
    28141 gaattggata cacctccatt tttcaaaaat cgttaagtaa atgaatgtaa aagaaaatac
    28201 agaacttgtt tttcgagaag ttgcagaggc tagtctgagt gctcatcgag agagtggttc
    28261 ggtctctgtc attgcagtta ccaagtatgt agatgtaccg acagcggaag ccttgcttcc
    28321 gctaggtgtt catcatatcg gtgaaaatcg tgtagataag tttctggaaa aatatgaagc
    28381 tttaaaagat cgagatgtga cttggcattt gattggtacc ttgcaaagac gtaaggtgaa
    28441 agatgtcatt caatacgttg attatttcca tgcattggac tcagtaaagc tagcagggga
    28501 aattcaaaaa agaagtgacc gagtcatcaa gtgtttcctt caagtaaata tttctaaaga
    28561 agaaagcaaa cacggttttt cgagagagga actgctggaa atcttgccag agttagccag
    28621 actagataag attgaatatg ttggtttaat gacgatggca ccttttgagg ctagcagtga
    28681 gcagttgaaa gagattttca aggcggccca agatttacaa agagaaattc aagagaaaca
    28741 aattccaaat atgcctatga ccgagttaag tatgggaatg agtcgtgatt ataaagaagc
    28801 gattcaattc ggttccactt ttgttcgtat aggtacatca ttttttaagt aggagagaac
    28861 catgtcttta aaagatagat tcgatagatt tatagattat tttacggagg atgaggattc
    28921 aagtctccct tatgaaaaaa gagatgagcc tgtgtttact tcagtaaatt cttcacagga
    28981 accggctctc ccaatgaatc aaccttcaca gtcggctggt acaaaagaga acaatatcac
    29041 cagacttcat gcaagacaac aggaattggc aaatcagagt cagcgtgcaa cggataaggt
    29101 cattatagat gttcgttatc ctagaaaata tgaggatgca acagaaattg ttgatttatt
    29161 ggcaggaaac gaaagtatct tgattgactt tcagtatatg acagaggtgc aggctcgtcg
    29221 ttgtttggac tatttggatg gagcttgtca tgttttagct ggaaatttga aaaaggtagc
    29281 ttctaccatg tatttgttga caccagtgaa cgttattgta aatgttgaag atatccgttt
    29341 accagatgaa gatcaacagg gtgagttcgg ttttgatatg aagcgaaata gagtacgata
    29401 atgatttttt taattcgtat gatttataat gcagtggata tttactccct gattttggta
    29461 gccttcgctg tcatgtcttg gtttccaggt gcctacgaat ccagtttagg tcgttggatt
    29521 gtagcgttgg tgaaaccagt gcttgctccc ttgcaacgcc tgcctttaca gatagcgggt
    29581 cttgatttat ctgtttgggt tgcgattgtt ttggttcgat ttttaggaga aaacctagtg
    29641 cgttttctgg cgatgatagg atgaataaag ggatttatca gcatttctcc atagaagatc
    29701 gtccatttct tgacaaggga atggaatgga taaagaaggt agaagatagc tatgctcctt
    29761 ttttaactcc ttttttaact ccttttatca atcctcatca ggagaagcta ttaaagattt
    29821 tggccaaaac ctatggtctt gcttgtagca gtagtgggga attcgtctcg agtgagtatg
    29881 ttcgagtttt attataccca gattatttcc aaccagagtt ttcagatttt gaaatatctc
    29941 tccaggaaat tgtgtattcc aataaatttg aacatttaac gcatgctaag attttaggga
    30001 cagtcatcaa tcaattaggg attgaacgga aactttttgg agatatccta gtagatgaag
    30061 aacgggcgca gattatgatt aatcagcagt ttcttcttct ctttcaagat ggactaaaga
    30121 aaattggtcg tatacctgtt tcgctggagg aacgtccttt caccgagaaa atagataagc
    30181 tagaacagta tcgagaactg gatttatctg tgtctagttt tcgattagat gttcttttat
    30241 caaatgtttt gaaactatct aggaatcaag caaaccagtt gattgaaaag aaacttgtcc
    30301 aagtaaatta tcatgtggta gacaaatcag attacactgt tcaagttgga gacttgatta
    30361 gtgtgagaaa atttggtcgc ttgagattac ttcaagataa gggacaaacg aaaaaagaga
    30421 agaaaaaaat aaccgtccag ttattattaa gtaagtgagg aatagaatgc caattacatc
    30481 attagaaata aaggacaaga cttttggaac tcgattcaga ggttttgatc cagaagaagt
    30541 cgatgaattt ttagatattg tggttcgtga ttacgaagat cttgtgcgtg cgaatcatga
    30601 taaaaatttg cgtattaaga gtttagaaga gcgtttgtct tactttgatg aaataaaaga
    30661 ttcattgagc cagtctgtat tgattgctca ggatacagct gagagagtga aacaggcggc
    30721 gcatgaacgt tcaaacaata tcattcatca agcagagcaa gatgcgcaac gcttgttgga
    30781 agaagctaaa tataaggcaa acgagattct tcgtcaagca actgataatg ctaagaaagt
    30841 cgctgttgaa acagaagaat tgaagaacaa gagccgtgtc ttccaccaac gtctcaaatc
    30901 tacaattgag agtcagttgg ctattgttga atcttcagat tgggaagata ttctccgtcc
    30961 aacagctact tatcttcaaa ccagtgatga agcctttaaa gaagtggtta gcgaagtact
    31021 tggagaaccg attccagctc caattgaaga agaaccaatt gatatgacac gtcagttctc
    31081 tcaagcagaa atggcagaat tacaagctcg tattgaggta gccgataaag aattgtctga
    31141 atttgaagct cagattaaac aggaagtgga agctccaact cctgtagtga gtcctcaagt
    31201 tgaagaagag cctctgctca tccagttggc ccaatgtatg aagaaccaga agtagctcca
    31261 atgcatccga taggtccaac accagctaca gaaactgttg attcaatacc gggatttgaa
    31321 gcaccgcaag aatctgttac aattttataa gaaatattct gagaacaata tcttatcctt
    31381 atatttccag cgagcaggag atggtgtgag tcctgtaatc cctattgata agattatcct
    31441 ctcaaaaact caagtctgaa gctagtaaga tttgacgttt cccacgttac gggataagag
    31501 ggagaaagac taaatctttt tccgaataaa ggtggtacca cgattttcgt cctttttgga
    31561 agtcgtggtt tttaatttgt tattatttat aaaggagata ccatgaaact caaagacacc
    31621 cttaatcttg ggaaaactga attcccaatg cgtgcaggcc ttcctaccaa agagccagtt
    31681 tggcaaaagg aatgggaaga tgcaaaactt tatcaacgtc gtcaagaatt gaaccaagga
    31741 aaacctcatt tcaccttgca tgatggccct ccatacgcta acggaaatat ccacgttgga
    31801 catgctatga acaagatttc aaaagatatc attgttcgtt ctaagtctat gtcaggattt
    31861 tacgcaccat ttattcctgg ttgggatact catggtctgc caatcgagca agtcttgtca
    31921 aaacaaggtg tcaaacgtaa agaaatggac ttggttgagt acttgaaact ttgccgtgag
    31981 tacgctcttt ctcaagtaga taaacaacgt gaagatttta aacgtttggg tgtttctggt
    32041 gactgggaaa atccatatgt gaccttgact cctgactatg aagcagctca aattcgtgta
    32101 tttggtgaga tggctaataa gggttatatc taccgtggtg ctaagccagt ttactggtca
    32161 tggtcatctg agtcagcact tgctgaagca gagattgaat accatgactt ggtttcaact
    32221 tccctttact atgccaacaa ggtaaaagat ggcaaaggag ttctagatac agatacttat
    32281 atcgttgtct ggacaacgac tccatttacc atcacagctt ctcgtggttt gacggttggt
    32341 gcagatattg attacgtttt ggttcaacct gctggtgaag ctcgtaagtt tgtcgttgct
    32401 gctgaattat tgactagctt gtctgagaaa tttggctggg ctgatgttca agttttggaa
    32461 acttaccgtg gccaagaact caaccacatc gtaacagaac acccatggga tacagctgta
    32521 gaagagttgg taattcttgg tgaccacgtt acgactgact ctggtacagg tattgtccat
    32581 acagcccctg gttttggtga ggacgattac aatgttggta ttgctaataa tcttgaagtc
    32641 gcagtgactg ttgatgaacg tggtatcatg atgaagaatg ctggtcctga atttgaaggt
    32701 caattctatg aaaaggtagt tccaactgtt attgaaaaac ttggtaacct ccttcttgcc
    32761 caagaagaaa tctctcactc atatccattt gactggcgta ctaagaaacc aatcatctgg
    32821 cgtgcagttc cacaatggtt tgcctcagtt tctaaattcc gtcaagaaat cttggacgaa
    32881 attgaaaaag tgaaattcca ctcagaatgg ggtaaagtcc gtctttacaa tatgatccgt
    32941 gaccgtggtg actgggttat ctctcgtcaa cgtgcttggg gtgttccact tcctatcttc
    33001 tacgctgaag atggtacagc tatcatggta gctgaaacta ttgaacacgt agctcaactt
    33061 tttgaagaat atggttcaag catttggtgg gaacgtgatg ccaaagacct cttgccagaa
    33121 ggatttactc atccaggttc accaaacggc gagttcaaaa aagaaactga tatcatggac
    33181 gtttggtttg actcaggttc atcatggaat ggagtggtgg taaaccgtcc tgaattgact
    33241 tacccagccg acctttacct agaaggttct gaccaatacc gtggttggtt taactcatca
    33301 cttatcacat ctgttgccaa ccatggcgta gcaccttaca aacaaatctt gtcacaaggt
    33361 tttgcccttg atggtaaagg tgagaagatg tctaaatctc ttggaaatac tattgctcca
    33421 agcgatgttg aaaaacaatt cggtgctgaa atcttgcgtc tctgggtaac aagtgttgac
    33481 tcaagcaatg acgtgcgtat ctctatggat atcttgagcc aagtttctga aacttaccgt
    33541 aagattcgta acactcttcg tttcttgatt gccaatacat ctgactttaa cccagctcaa
    33601 gatacagtcg cttacgatga gcttcgttca gttgataagt acatgacgat tcgctttaac
    33661 cagcttgtca agaccattcg tgatgcctat gcagactttg aattcttgac gatctacaag
    33721 gccttggtga actttatcaa cgttgacttg tcagccttct accttgattt tgccaaagat
    33781 gttgtttaca ttgaaggtgc caaatcactg gaacgccgtc aaatgcagac tgtcttctat
    33841 gacattcttg tcaaaatcac caaactcttg acaccaatcc ttcctcacac tgcggaagaa
    33901 atctggtcat atcttgagtt tgaaacagaa gacttcgtcc aattgtcaga attaccagaa
    33961 gttcaaactt ttgctaacca agaagaaatc ttggatacat gggcagcctt catggacttt
    34021 cgtggacaag cacaaaaagc cttggaagaa gctcgtaatg caaaagttat cggtaaatca
    34081 cttgaagcac acttgacagt ttatccaaat gaagttgtga aaactctact cgaagcagta
    34141 aacagcaatg tagcacaact tttgatcgtg tctgagttga ccatcgcaga aggaccagct
    34201 ccggaagctg cccttagctt cgaagatgta gccttcacag ttgaacgtgc tactggtgaa
    34261 gtatgtgacc gttgccgtcg tatcgaccca acaacagcag aacgcagcta ccaggcagtt
    34321 atctgtgacc actgtgcaag catcgtagaa gaaaactttg cggaagcagt cgcagaagga
    34381 tttgaagaga aataagattg aaaagtctag gcaaaattca atttgagaag aaaagacaac
    34441 taattttata gtctattaaa cgcattgtat cacgtttttg aatacctgat atgatgcgtt
    34501 ttttatttat tttaaaaatt tgcgaggtat gactttttat actcaacaag aatcaaagag
    34561 aaacttagca agctaacagt agtaagataa aataggaatt tgatatt
//
LOCUS       DAVMCG010000017        34442 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVMCG010000017 DAVMCG010000000
VERSION     DAVMCG010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34442
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.017"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(30..188)
                     /locus_tag="VYP66_001028"
     CDS             complement(30..188)
                     /locus_tag="VYP66_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1850594.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(260..637)
                     /locus_tag="VYP66_001029"
     CDS             complement(260..637)
                     /locus_tag="VYP66_001029"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1850595.1"
                     /translation="MRRKFFEAPPKQADKSSLGAKGLAYCDQLFSLERDWEALPADER
                     LQKRQEELQPLIEDFFAWCRRQSVLSGSKLGRAIEYSLKYEETFKTILKDGHLVLSNN
                     LAERAIKSLVMGRSKRVHWTLLA"
     gene            complement(786..1376)
                     /locus_tag="VYP66_001030"
                     /pseudo
     CDS             complement(786..1376)
                     /locus_tag="VYP66_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1300..1494)
                     /locus_tag="VYP66_001031"
     CDS             complement(1300..1494)
                     /locus_tag="VYP66_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1850596.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1691..2014)
                     /gene="tnpB"
                     /locus_tag="VYP66_001032"
     CDS             complement(1691..2014)
                     /gene="tnpB"
                     /locus_tag="VYP66_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1850597.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWLSTEKDVKALAPEQVDWLMKGFS
                     ITPKI"
     gene            complement(1995..2180)
                     /locus_tag="VYP66_001033"
     CDS             complement(1995..2180)
                     /locus_tag="VYP66_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850598.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MIEQLLDKVLLYDNSSI"
     gene            complement(2484..4046)
                     /gene="guaA"
                     /locus_tag="VYP66_001034"
     CDS             complement(2484..4046)
                     /gene="guaA"
                     /locus_tag="VYP66_001034"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1850599.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4188..4886
                     /locus_tag="VYP66_001035"
     CDS             4188..4886
                     /locus_tag="VYP66_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1850600.1"
                     /translation="MLPAYMKIHDQIKKDIDEYRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4929..5825)
                     /locus_tag="VYP66_001036"
     CDS             complement(4929..5825)
                     /locus_tag="VYP66_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1850601.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     IGMAMILFAVTLISLKDLFLEK"
     gene            complement(5834..6769)
                     /locus_tag="VYP66_001037"
     CDS             complement(5834..6769)
                     /locus_tag="VYP66_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1850602.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6766..7491)
                     /locus_tag="VYP66_001038"
     CDS             complement(6766..7491)
                     /locus_tag="VYP66_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1850603.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDIASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7575..8210)
                     /locus_tag="VYP66_001039"
     CDS             complement(7575..8210)
                     /locus_tag="VYP66_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1850604.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEREEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(8212..9039)
                     /locus_tag="VYP66_001040"
     CDS             complement(8212..9039)
                     /locus_tag="VYP66_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1850605.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9061..9397)
                     /locus_tag="VYP66_001041"
                     /pseudo
     CDS             complement(9061..9397)
                     /locus_tag="VYP66_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(9398..10114)
                     /locus_tag="VYP66_001042"
     CDS             complement(9398..10114)
                     /locus_tag="VYP66_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1850606.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRVQAPLVIKEVNGIKVALLAYSYGFNGIEQYISKEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSEMVEKDGDKKLIIY"
     gene            10627..11238
                     /locus_tag="VYP66_001043"
     CDS             10627..11238
                     /locus_tag="VYP66_001043"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1850607.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11283..12011
                     /gene="rlmB"
                     /locus_tag="VYP66_001044"
     CDS             11283..12011
                     /gene="rlmB"
                     /locus_tag="VYP66_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1850608.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12050..12961)
                     /gene="trxB"
                     /locus_tag="VYP66_001045"
     CDS             complement(12050..12961)
                     /gene="trxB"
                     /locus_tag="VYP66_001045"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1850609.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13027..13251)
                     /locus_tag="VYP66_001046"
     CDS             complement(13027..13251)
                     /locus_tag="VYP66_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1850610.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13329..14072)
                     /locus_tag="VYP66_001047"
     CDS             complement(13329..14072)
                     /locus_tag="VYP66_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1850611.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVAFIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14072..14872)
                     /locus_tag="VYP66_001048"
     CDS             complement(14072..14872)
                     /locus_tag="VYP66_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1850612.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15030..15386)
                     /locus_tag="VYP66_001049"
     CDS             complement(15030..15386)
                     /locus_tag="VYP66_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1850613.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15399..15911)
                     /locus_tag="VYP66_001050"
     CDS             complement(15399..15911)
                     /locus_tag="VYP66_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1850614.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGEPQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNK"
     gene            complement(15911..16405)
                     /locus_tag="VYP66_001051"
     CDS             complement(15911..16405)
                     /locus_tag="VYP66_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850615.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16540..16986
                     /locus_tag="VYP66_001052"
     CDS             16540..16986
                     /locus_tag="VYP66_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1850616.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16983..17630
                     /locus_tag="VYP66_001053"
     CDS             16983..17630
                     /locus_tag="VYP66_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1850617.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17651..18232)
                     /gene="pdxT"
                     /locus_tag="VYP66_001054"
     CDS             complement(17651..18232)
                     /gene="pdxT"
                     /locus_tag="VYP66_001054"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1850618.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREGILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18233..19108)
                     /gene="pdxS"
                     /locus_tag="VYP66_001055"
     CDS             complement(18233..19108)
                     /gene="pdxS"
                     /locus_tag="VYP66_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1850619.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19260..20639)
                     /locus_tag="VYP66_001056"
     CDS             complement(19260..20639)
                     /locus_tag="VYP66_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1850620.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20933..21856
                     /locus_tag="VYP66_001057"
     CDS             20933..21856
                     /locus_tag="VYP66_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1850621.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21916..22521
                     /locus_tag="VYP66_001058"
     CDS             21916..22521
                     /locus_tag="VYP66_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1850622.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22540..23784
                     /locus_tag="VYP66_001059"
     CDS             22540..23784
                     /locus_tag="VYP66_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1850623.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24007..24264)
                     /locus_tag="VYP66_001060"
     CDS             complement(24007..24264)
                     /locus_tag="VYP66_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1850624.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24306..26342)
                     /locus_tag="VYP66_001061"
     CDS             complement(24306..26342)
                     /locus_tag="VYP66_001061"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1850625.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26554..27471)
                     /gene="glyQ"
                     /locus_tag="VYP66_001062"
     CDS             complement(26554..27471)
                     /gene="glyQ"
                     /locus_tag="VYP66_001062"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1850626.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27666..28427)
                     /locus_tag="VYP66_001063"
     CDS             complement(27666..28427)
                     /locus_tag="VYP66_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1850627.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDLNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSEQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28700..29542)
                     /locus_tag="VYP66_001064"
     CDS             complement(28700..29542)
                     /locus_tag="VYP66_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1850628.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSITISRIQANLDCFGIELSHKERETLKTIAVQLGAPRVD
                     DVDF"
     gene            complement(29656..31047)
                     /locus_tag="VYP66_001065"
     CDS             complement(29656..31047)
                     /locus_tag="VYP66_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1850629.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31282..31659)
                     /locus_tag="VYP66_001066"
                     /pseudo
     CDS             complement(31282..31659)
                     /locus_tag="VYP66_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            31892..32869
                     /locus_tag="VYP66_001067"
     CDS             31892..32869
                     /locus_tag="VYP66_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1850630.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLTG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            32866..33948
                     /locus_tag="VYP66_001068"
     CDS             32866..33948
                     /locus_tag="VYP66_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1850631.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(34012..>34442)
                     /locus_tag="VYP66_001069"
     CDS             complement(34012..>34442)
                     /locus_tag="VYP66_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1850632.1"
                     /translation="HSHYIREFRYCYGAVDAHTGESFFLIAGRCNTEWMNAFLEELSQ
                     AYPDDYFLLVMDNAIWHKSSILKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNK
                     AFRILEDVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
BASE COUNT        10196 a         7705 c         6192 g        10349 t
ORIGIN      
        1 tcacggatag ttcctaatct ggagatttct tatttgcact tttcttgtac aactttagtc
       61 cacggtaaat aggcctctaa aacctctttg tttacgagag tttcctcgtt tggaagacat
      121 tctagaagat aggatagata tttctcacta tttagttgat gacgtttagc tgtttccaat
      181 aagctcataa taatagctct tgctttagct ccttcaaaaa ctttgagaaa acaaccaccc
      241 tcgctttttt aaactgagct taggctaaaa gagtccagtg gactctttta ctccgtccca
      301 taaccaatga tttaatggcg cgttcagcta gattattgga aaggaccaga tgtccgtctt
      361 ttaaaatggt cttaaaggtt tcttcatact tgaggctgta ttcaattgcc cttcctagtt
      421 ttgaacccga taaaactgac tgacgacggc accaagcaaa gaagtcttct attaggggtt
      481 ggagctcttc ttgacgtttc tgtagtcgtt catcagctgg caaagcctcc cagtctcttt
      541 ccaaggaaaa taactgatca caataggcta atcctttagc tcctaaagat gatttatccg
      601 cttgcttggg gggcgcttca aaaaacttcc ttctcacatg tgcccaacat ccaacaagtt
      661 cagcttctgc cagttgactg acgataagct tctagcggtt cgcagtttac caagcttagc
      721 gtcgccttgc tcctaaacct tggactgcta tcgcataggc agaactagag gactaaagtc
      781 ctaagttact gccgcaacat gtcacaatgc acatagccag aataatctcc taggaattct
      841 tgtactacta aaccactccg acgctgatca tggtggtaca gcgtgattgc ttgattttca
      901 gctttcccag acaaaaaggt ccaatagtag gtcagctgac tatcactctc tagcacccta
      961 taagaagttt catctgcatg aagtaagggc ttgagtcaat agtctcgtta taaaggggct
     1021 ttaggaatag gagctttcac gattttatca ctcggatttt tatcactgca tgcttggcat
     1081 ttgtaagcgt gttggatatg atctatgcgt tttaattgcg caggaataaa gaccaattct
     1141 tgtccttgaa gactccctcc aatctctttt agatctccct gacaatcagg gcaaatcctc
     1201 tcttctactt gatgatgaac ttcttctgaa tcaaattggg caagaagagc ttggcgtttc
     1261 cctttagatt tcttacgttt gtaggtaatt tcttctgttt caactgggaa catctccatc
     1321 ttcctcagat ggagactctt cctcaaaaag gttgagttgt ccagaggggc aaacactttt
     1381 ctcagaggat tttccataga gcttttgagt cagataagcc acttgttcac gcagaagggc
     1441 aagttcattg gtgagactat caattgtagc actctgttgt tgaatgattt tcaatcttct
     1501 tccatgagct tccctctctg ttttctaact ttattatact aaaaagaaag tcctcatttc
     1561 aatagaaatc acgactttct gatggattta tagtaaaatg aaataagaac aggacaaatc
     1621 gatcaggaca atcaaatcga tttctaacaa tgttttagaa gcagaggtgt actattctag
     1681 tttcaatcta ctatattttt ggagtgatag aaaagccctt cataagccaa tctacttgtt
     1741 caggtgcgag agctttgaca tccttttctg tacttagcca agtcagtttt ccgttctcaa
     1801 agcgtttata taatatccaa aatccttgac catcccagta aaggacttta aagcggtctt
     1861 tacgtccacc acaaaagaga aagacttgat cggagaaagg atccaattca aagtgggttt
     1921 taaccagata agccagtgaa tcgattcctt gtctcatatc cgttttccca catacgagat
     1981 agacctgccc taggctagat agatgaattg tcatagagca acaccttatc caaaagctgt
     2041 tctatcattt cgagattgag agattgaaaa aaacttactt caagcttgcc aatacgaatt
     2101 ttaagcagaa tatcatttct ctttttagaa tcaaaaggac gagattgtgg aatctctaca
     2161 ggaacaatag gttgtggcat taaaatatcc tccaatagtt ttactttact aatagtatac
     2221 aggaggagct ccatgaatga tagatacctt gttatgacgc gcttactata ttagaaagtt
     2281 ggctctctaa ttaaattaat tctcattata tatatcaaaa gaccgcagtt tgaaaactac
     2341 ggtctaattt tttgtccaaa tgtaaaccac ttggaactat tattcaattt attcttttta
     2401 gcaaatgttc ccgttttaat cccagttaca gtttttaatc ctctgtaacc gttgatttta
     2461 caaagctttt aatttttttg cgattattcc cactcaactg ttgcaggtgg tttacttgta
     2521 atatcgtaga cgatacggtt aacatgatcc acttcattta cgatacgtac tgagattttt
     2581 tgaagtactt cccatggaat tttggcaaaa tcagcagtca taccatcgat agaagtgata
     2641 gcacggattg caatcgtgta gtcatacgta cgaccgtcac ccataacacc gactgaacga
     2701 acgcctgtgt taacagtgaa gtattgccaa atatcgcggt caagtccagc tttagcgatt
     2761 tcttcacgaa gaatagcgtc tgattcacga acggtttcaa gtttctcttc agtgatttca
     2821 cccatgacac ggatagcaag tcctggtcct gggaatggtt ggcgccatac gatatggtct
     2881 ggcataccaa gctctgtacc aagagcacga acttcatcct tgtaaagagt attgagtggt
     2941 tcaatcaatt caaactgcat atcttctgga agaccaccca cgttgtggtg tgacttgata
     3001 gtttgagctg tatccgtacc agactcgata acatctgtat ataaagtacc ttgagcaagg
     3061 aatttcacat ctttgagctt gcttgcttcg tcatcgaata catagacaaa ctcgttaccg
     3121 atgattttac gtttttgttc aggatcagaa acgccagcaa gtttgtcaag gaaacgttta
     3181 gcagcgtctg ctttgacgat attcaaacca aacttaccac cgagcatgtc cataacttga
     3241 tcagcttcgc ctttacgaag aagaccgtgg tctacgaaga tacagatcaa ttgatcgcca
     3301 atcgcttttt ggagaagaac cccaacgaca gatgagtcaa caccacctga tagaccaaga
     3361 aggacacgtt tatcaccgac ggtttcacga atttttttga tctgcatgtc aatgaaatta
     3421 tccattgacc agtcaccttt agccttacaa atgttaaggg caaagttacg aaggatatca
     3481 tttccgtata cagaatgacg aacttctggg tggaattgga taccgtaaat gtgtttatct
     3541 gggttttcga tggctgcgta tgggcagtca gctgatgtac ctgtacgaac aaagtcagca
     3601 ggaatctcag taaccgcatc accatggctc atcaaaacag tctgttcatc aggtgttgat
     3661 tcaaaaagcg ctgatggtgt gtgagttagg gttgattgac cgtattcacg atttccagca
     3721 tcacctgcag gaacaacttt tcctccaagt ttatgggtca ataactgcat accataacag
     3781 attcccaaaa ttggaattcc gagttcgaag atttctgggt caatatcaaa tgaaccatct
     3841 tcatatacag aatttggacc acctgataga ataattccta caggattgac ttcacgaact
     3901 tcagcagctg aaattttatg gctttttagt tctgaaaaaa caccaatctc acggatacgg
     3961 cgtgaaatca gctggttgta ctggctacca tagtccaata cgatgatttt ttctacatct
     4021 tgcaaatcag ttgaaatgtt gctcatcttt ttcctttctc aaaagaaata tcttttccca
     4081 atattctatc acaaataagg gcgaattacc aactaaacaa ggcgaagttt gactttttct
     4141 agtttattgg ggtacaatag agaaaagata gaaatgaagt gaaaaatatg ctacctgctt
     4201 atatgaaaat ccatgatcag ataaaaaagg atattgacga gtaccgttgg gctattggtg
     4261 agaggcttcc cagtgaaaga gatctagctg agcagtttgc ggtcagtcgc atgaccctcc
     4321 gccaagccgt atctctatta gtcgaagaag gcgtcttaga gcgccgtgta ggaagcggca
     4381 cctttgtttc cagtactcga gtacaagaaa agatgcgagg gacaaccagt tttactgaaa
     4441 ttgtcaaatc ccaaggtaaa gttccctcta gccagctcat ttcctacaaa aaaaccattc
     4501 ccaatgagca agaagttgcc aagctaggaa tttttccaac ggacaatatt atccgaatgg
     4561 agcgggtccg ctatgccgac caagttcccc tagtttatga agttgcttct attcctgaaa
     4621 aattcattaa ggactttaaa aaagaagaaa tcaccagtca tttcttccaa accttgcaaa
     4681 aacatggcta tcgtatcggc aaatctcaac agaccatcta tgctcgcctt gctaaagaaa
     4741 agattgccca ctatttggaa gttgaaaaag gacatgctat tcttggattg acccaggttt
     4801 cctacctaga agatggtact gcttttgaat acgtaaaaag tcaatatgta ggcgaacgct
     4861 ttgaatttta tcttgaaaat aattagatta ccacgcaaaa actctctgtc acgaacaaag
     4921 agtctttttt atttttctaa gaataaatct ttcaaagaaa tcaaagttac agcaaacaat
     4981 atcattgcca taccaataaa atcaatggga taaaattgtt cattcattat taagaaggca
     5041 aagaaaaccg ccgatattgg ctcaattgaa gccaacaagc ttgacttgac cggtcctatc
     5101 agactggctc ctttaaggaa agctgtatag gcaaagacag tcccgataag gataatgcct
     5161 gcaaacgcaa ggagaaaatc aagactagtc gggatatcgg cctgtagaac ccctgtaaaa
     5221 ggaagggcga ccaaacctgc tatgaccatc cccacaccaa tgaccaagct gctcccccac
     5281 tttttaatca aggctatggg taaaatgata tacagagcat aagtcaaggc agaaaagaga
     5341 ccccagaaca ggccagcagg tgtcatggat aactggtcca actgcccatg tgttgcgatc
     5401 aggaaggttc ctccgatggc gaatatgatg gaaactatct ctcccagtgt cggtgccacc
     5461 ctatccttga tacagctata aattaaaatt ccgacaggac aaacatactg aagcaccgtc
     5521 gctgttcccg cattggtctc ctgaatagca gacagatagg cgaattggtt gagaaaaaga
     5581 ccaatcagag caaaaataag aagagacagc aaactctttc tatcctttaa aaagaccagt
     5641 attttatcct ttgcagtagc ataagccaag agcatgagaa ttccaccagc gattaaaaga
     5701 cgcaagttgg tcaagaccag agccgaaatt ccgtgtgcca ttaggtattg gccactcgtt
     5761 cctgacaacc cccaagcaat accagccaca actgttagta aagtcccttt taaactattt
     5821 gacatgtctc tccttactct tctttgcgaa tcaagttcat cacttgattg cggtctaata
     5881 tccattgagc tctctcgtcc ttttcatagg tacgattcga taggaaaata gtggcttctt
     5941 gcttctgacg attccacatg ataaaggtac ctgtatagcc cgtatggtct agccaatctc
     6001 cttccaaatt ccatgctaaa gaacgttcct tgtcatccaa aggagaaaaa ttttgattta
     6061 agtctcttgc aaaatcatct gctaaatagt gttctaaaaa gatttgtaaa tcctttatag
     6121 tcgaaaataa accagcactc ccagcatgtc tacccaggag acgagccttg ggatcatgca
     6181 ctatgcctgc ctctacacct ctaactgttg gaacagcaag ctcaactggc ccaaacttgg
     6241 tttccgtcat tccccaaggt ttccagactt gatcctttaa aatcacatcc aaatcttgat
     6301 taaaaattct ttccaaaata aagcccaaca gcaaaaaatg gacatccgaa taaagaaagg
     6361 ctggctgact tcgtctgttg agatgaaaca tcgcttcctt taattcaggg gctgttaaaa
     6421 gatcacgatt aggaataaaa ggatcaaggt ctgttgcatg agtcaagagc tggcgaatag
     6481 tgatgtctgg ataatcactc tcaggtaaaa aatctattac cagtctatca atatctaatt
     6541 gacctatttc ccacaagaag gtacaaactg tgccaacccc aacaaccttg ctgacactag
     6601 ctaggtcata aactagtcct gcctcagtct gcaagccatg ctctgggtca ctctggccta
     6661 aatagaactc tgtccattga ttgtccttaa aatacgcaaa agaggctccg ggataaattc
     6721 ctgcctcgat ttgttcttct atttttttaa taatcttggt ccacttcata cttcttcaaa
     6781 ccacaattca acattatttc tatctttaca aaggaagaat ttttcagact taggaataaa
     6841 atattcagta gactcaaact tctggcgaag acttgctatg tctaattcat tgaccaagaa
     6901 cttgagcata gataagtccc aggtaaccgt attgtccaca gtcaaatcct gcccctgagc
     6961 tggaataaaa tcaagggatg ccccaatttc agatgattcc aagaaacttt cgatatcagt
     7021 tgggagatgt aattccatag aaatctcaaa tttacttaaa gaaattgatg ccaaatctgt
     7081 ttgaaattca ggcttttctc ctacttctac tagacttgct atgtcatctt ccgcatgaat
     7141 caaaatcaaa tcatcttctg gtgagaaaat ttcaaaagcg tagccatttt gacctttata
     7201 taatcgatga atcgaatctg ttttagataa gattccttca atttctaagg gattttccac
     7261 cttgacaatc aatctagcta gtttttttct tccctctacc ttacgagtac gcatactggg
     7321 agcttcttct aaaaccagct tttcaagacc cgtttggtca cctagtgaca gaaaggccga
     7381 ttcttctaac aaggccttca ttccaagggt ttcaatataa aatgtttcat ttaattttct
     7441 attattagct tttaaagtag gaataatccg tacaatctga tttacattca taaattcctc
     7501 cgtcactttt tattttaaag gattttagaa ttttttacaa gatattatgc tcaaatttaa
     7561 cattatttag ctatttagta aagatagtct ttcaaggatt ttgacaaagc ctgataacca
     7621 gcaatactga ggtgcagtcc atcagttgta tattcttttt tgagttggcc tgcttggtct
     7681 gtcaaacaat caaatactgg cacaaattcc acctgcatat aggcagatgc aagctcttga
     7741 taggcttgat tccagttctg aattttttca ttcgagcgga tatagactgc ctgctggtac
     7801 tcctctctct cattgacagg caaaatggaa agcaatttaa tctctgtcaa tggataatcg
     7861 cgagcaacgg attgaatgat agcttcgaga ttattgagag cctcattcac aggaacatcc
     7921 tttccgatat catttgtccc aatcagaaga aaaattttat ctactgctcc accatataga
     7981 tgagcatcaa ggttctctag taacagtcct gtctgatagc cacgaattcc tcgattgaca
     8041 atcgtctttg aagtcccaaa tagctcctgt agaggataat actcgacaat ggaatcccca
     8101 ataaaaagaa tgtttggttc tacaacagaa atgtgattta ggtgacgata cttagtttga
     8161 attttttctt gttcctttag gagccaattt tctaataact gtactgccac ttcattctcc
     8221 tttttctaac cagttttcca aaacttgata aactcctcct tggctgttgg ctggtgctag
     8281 agcagtcgcc acagctttgg ctttctcatc agcattttcc atcgcatagg caattccagc
     8341 catttcaagc atttcaacat cattttcact atcaccaaaa gccatgattt cttgggattt
     8401 caagtcccag cgcttgagta attcctccaa gccccatgct ttatgaatcc cagcttggag
     8461 gatatcaatg caaccatagc cactggatac agctcggaca cggccatcaa agagagcatt
     8521 gatttcttcc aaaaccgaac tcaaacgttc ctcaccaaca accatgctca tcttgagcac
     8581 accaccaaag aggtcagatg ttaattcatc cacaaattgc atccgttggt agaatttttc
     8641 aatcatttct ggagtcataa aactttcaag atctgtaaaa atcgtacctt ccttgacaaa
     8701 atcacccttc atccccgtta caacaaactg gtcctgacac gctcgaccct tgaaatgagc
     8761 caaagccttg ttgacaatgg cgtcatccca tgtctgagcc tgaatcaatt cattgttttc
     8821 aaaaatacga gcgccattag caacaaccag aaccactcga tccaccaagg gactcagtag
     8881 ttgtctcatg cggtgaattt cattgcccgt cgcaatgaca aaacgaatgc ccctttgatc
     8941 caactgatct aaaatctttt ccaatcgtgg gagatcaagc tgacccctag catccagcaa
     9001 ggtcccatcc atatctgtcg caattacctt aatcatcatt tactttcctc tggattcaag
     9061 ctaataccac ttcaatccca catgttcatt catttcttta taggctgtat caattcgttc
     9121 cttagtcgct tcatctaact ggtcacgatg actgccaccc ctctataaaa tcttccaaaa
     9181 tataagtttg gtaatgatac aagggatatc cttctggtga aaaggttccc tttggtgttc
     9241 gattgaccca agtaggatga gctttagctg ttccgatagt tgtttttcca tccttcttct
     9301 tgatggtgac atccatgaga acaccacgtt cagtccactt agcattctct tcatctccca
     9361 tagattcaat tcgttgattg gaaatgaagt tccccattta atagataatg agtttcttat
     9421 ctccatcttt ttcaaccatt tcagatggtt caacaacgtg aggatgccct ccaaagataa
     9481 tatccgctcc ccaatcgatc atcttgtgat aaagagcttt ttgttcttca gttggttcca
     9541 atcgatactc aacacccatc tgaagcatga taatggtgat atctgcttcc ttctctgccc
     9601 gttcaatttc agccttcatc ttatcttcgt ttaaatctga aagataacga ttatagtctt
     9661 ccttagaaat atactgctca attccattga aaccatagga ataggctaac aatgcaacct
     9721 tgataccatt cacttcctta atgaccagcg gagcctgaac acgtggttcg tgcgtataaa
     9781 ctccgattgg agtgattcca gctttctcaa taatatcggc cgttgaaata actccctcaa
     9841 tttgcgaatc caaaatatga ttatgagcta aatccagcac atgataacct gcctccttaa
     9901 tagcatccat aacttcaaca ggagcattaa agagaagata acccgctaaa taatgatcct
     9961 tattaatggt tccttcaaaa tcaccaatag ctaaatctgc ttgcttgagc caaggagtca
    10021 catactcaaa attttcatga aagtcatagg taccgtcttc ttttttagct gaaaagaaaa
    10081 gtccatcgtg gtagagcaaa tccccgtggg ccataattct ggcagttttt tcctcttcct
    10141 actcctgaga cttttgctta gtcccctctt gagaaatagt atctcgtttt tgactagtca
    10201 agggattcct tggaagcttt caaacaacaa gaccaagccc attgataaac caactgctag
    10261 caagagtatc gccacaaatc ccttattgct ccacttgcga taactcctaa aaagtttacc
    10321 aagcccttca taaaacgaaa agctaaacca ccctgatttc gattttgtct tctttgtatc
    10381 ttcgttctcc ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt
    10441 tctttcacaa ttgaattgaa cttcctatct attttctata aatcctaaat gccataatgc
    10501 tttcaattct tgtcattttg tgatatcatg tagaggaaat gaactaatcc acagtggctt
    10561 attccaagta taccacttgg gctttggcag tagctaactg cactaaacat aatataagga
    10621 gagaaaatgt ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat
    10681 attatccgtg aagggaatcc tactctacgc acggttgctg aggaagtcac tttcccccta
    10741 tctgaccagg aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagat
    10801 cctgtcatgg ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta
    10861 gatatctcaa aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact
    10921 ccacaggaag cctacgattt ggaagccatt atgtacaatc caaaaatcgt ctctcactct
    10981 gttcaagatg ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct
    11041 ggctatgttg ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa
    11101 caccgtatca aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt
    11161 aacggtatca tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt
    11221 ttactgattc ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag
    11281 gcatgaaaac aaatgatatt gtctatggtg tccacgccgt taccgaagcc ctccttgcaa
    11341 atacaggaaa caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca
    11401 aggaactagc tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa tctctctctg
    11461 agatgactga aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata
    11521 gcgagctaga ttacatcctt gcaaaaacac gccaagaaga aaatccactt ctattgattc
    11581 tagatggtct aactgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca
    11641 atgtttcagg tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct gtcgttgcca
    11701 aaacagccac aggtgctatt gaacacgttc caattgcccg agtgacaaac ctcagtcaaa
    11761 ccttagataa actcaaggat gaaggcttct ggacctttgg aacggatatg aacggtactc
    11821 cttgccacaa gtggaataca aaagggaaaa tcgccctcat catcggaaat gaaggaaaag
    11881 gcatctctag caacatcaaa aaacaggtcg atgaaatgat taccattccg atgaatggac
    11941 atgttcaaag cctcaatgcc agtgttgctg cagccattct catgtacgaa gttttccgaa
    12001 atagactata aaaaagtttc cagtcatctg attggaaact tttttatgat taactatgtt
    12061 ctgtgataaa cttgtaggct tcttgaccag cgatagctcc atctccaact gctgttgtta
    12121 cttggcgaag gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagttt
    12181 tcatgtggtt atctgtcaca atccatcctg cctgatcttg gatattcaat tctttaacaa
    12241 aatcgctaag agggtccaat ccaacataga taaagacacc accgaaggct tgttctgtca
    12301 cttgacctgt tttcacattt tcaaatacga ctgattctac tcggttttca cccttgattt
    12361 tccttactac agaatcccat ataaagctga ttttctcatt ggcaaaggcg cgatcttgta
    12421 aaaccttttg ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac
    12481 gagtcaagaa gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt
    12541 ggtcacggaa gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt
    12601 cttcttctcc aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac
    12661 gtgtttcata tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat
    12721 tttcaacata accataaatg tgctccacac caagattttc aagtggttca aacatctttt
    12781 cagccaattc aggtccacta atattagcgt atcctgggta attttcgata tcagatgtat
    12841 tattcatctg accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag
    12901 cagcatacaa ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca
    12961 tatagattcc ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg
    13021 caaggattat gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac
    13081 aaccaagact ccaatcataa tcatatcata gagatgggct tggcgagcct tggctgtctt
    13141 atcaactccc gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat
    13201 ggtggtcaat atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct
    13261 catttctatc ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat
    13321 ctattatatc aaatataagt ccgtttgtaa ctagcgaaga attcttttgt ccgctcttct
    13381 ttaggggtgt ggataatctc atccggagtt ccagactcga tgattttccc cttatctaag
    13441 aagagaatct tatccgcaac ttgggctaca aaggacatgt catgactgac caaaatcatg
    13501 gtctgacctg acttagcagc atctgcaata gacttttcta cttcaccgac caattctggg
    13561 tcaagggctg aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc
    13621 gctagggcaa cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg
    13681 tccgaaagcc caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat
    13741 aatttcttga caacaaccaa gccttctttc acattatcaa gtgctgttcg gcgttcaaac
    13801 aaattaaact gttggaaaac catagacaac ttacggcgta gggcaaggat ttcttcttga
    13861 gtaattttag aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt
    13921 tcaagataat tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaataaag
    13981 gctacaactt cccctttttg aatatccaag tccagatgat ccaagacagt ctgtcctgaa
    14041 aaggatttgc ttaaattcga aatcttaatc attaacgaag gtctcctttc acatctgttt
    14101 gcactgtatc aggtgcagaa atagccattt ttctctcgat gaaacgaccg aggctttcaa
    14161 ttccgatatt gactacccaa taaacaaggg caacggagat gaagcgttca aaatagcgat
    14221 aatcagctcc acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag
    14281 ctagagatgt tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca
    14341 ccgctgcatt aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc
    14401 gtgccgcctc aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag
    14461 cataagctgc ctcattaaag gcaaaggcga caatcgcaaa agctgcagct ggaatcgcat
    14521 tgatattgag accagttccc cattgctgat tgagggcttt caaagccaaa gggattccgt
    14581 agtaggtcaa catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg
    14641 cctgcaaggg atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca
    14701 aaaccaaacc aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga
    14761 caattctagg gattccatca aagaccgaac gtaggctaaa cagcttgcca tccggaatca
    14821 attgcatcaa gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat
    14881 cctcttctga taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg
    14941 gtcagataca gactttgtct acctactagt ttatcatact ttgaaacagg gaagttatat
    15001 attttatcta tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt
    15061 cgataaccga tttgcttaac agttccattt tctactaaaa tgggccgttt taacaacata
    15121 ccgtcacttg ctaacaactc agccgcttct tggtttgaca aacttcctac cttatctttt
    15181 agccctaatt cacggtattt gattccactg gtgttgaaaa attgcttcaa ttcaaatcct
    15241 gaggtttcta gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg
    15301 gctttatagt ccacacctaa ttgatttaat tcttgttttg cttttttaca agttgaacat
    15361 ttggggtatt cgataaattc taacatgtgc ttctccttct atttgtttct atctttaaaa
    15421 tctactcctt catgctccaa gagccaagct ttcttttcca ctcctgcagc atagcctgtc
    15481 agacgcttgc ctgctcccaa cacacgatga caaggtacta ggatagacca aggattgcgt
    15541 cccactgctc caccaattgc ttgagcagaa gccacttgca ggtcttgagc aatttgtcca
    15601 taggtcactg tctgaccata aggaattccc tgtaaatagg accaaactct cttttcaaaa
    15661 ttcgttccaa ttggcgccaa gagcaagttg gataaatcct gaggctcgcc tttaaagtaa
    15721 tcatctaagc aagcaataac tgggtctaaa ataggatgac taacaacttc ttctatcgtt
    15781 tcatctccta gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc atacaaataa
    15841 tggtcatcag ctacaagtga tagaatacca attggtgagg agtagaggat ttttacatac
    15901 ttcttttgca ttatttcttt aatttttgat aggccaagcg ttcgccatct actggcacct
    15961 taccaacttg tttaaaacca agtttttcaa aaatatgttg cataaccttg ttttcagcat
    16021 gcgtatctga gcgaaaatca agataatcaa aaccttcaat caagccctct aagaaggttt
    16081 gagcaactcc ttttccctgc acatctgctg ccacagcaat acggtgaaag actagatact
    16141 ctgactctcc agcttgccag tttccctcat aaatagcttc ataggcctcc tctggactct
    16201 tggtcacagc agcataggct agcagttctc cctcttccaa ggctacgtag gcttgccctg
    16261 agatgatatc atcgataata acatctgcat ttggatagcc attttgccac tggttactac
    16321 cagcatctgc taaacatttt ttggcatcct ctatcacctg catgatggca tctacttcat
    16381 ttggaaaagc taaacgaatt tccatctttt ttcctcattt ctgactagtt tctcccatca
    16441 tagcataatt taagtctttc tacaagcagt taaaacttga ctttgtattt ttgttatttt
    16501 ataatctagt tatcaaaact atataaaaag gagttgaaaa tgaaaactac cttttcctac
    16561 ccaaaatggg cagaaattcc aaacattaac ctctatctgg accaggtttt gctctatgtc
    16621 aatcaggtct gcgcccctat ctctcctaat aaagacaaag gcctaacagc atctatggtc
    16681 aacaattatg tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata ccaacgccaa
    16741 cagattgccc gtttgattgc tatcacaacc ctcaagtctg tattttctat tcaagaaata
    16801 gcccagacac ttaatactct acaaactcaa gcaagttcag accaactcta cgatgctttt
    16861 gtggactaca tgaaccaagg aattgaccca gctaacccta ttatccaaac cagctgccaa
    16921 accgttaaac tctatcatca aactctagac ttaatcgatc atactcaaga ggaggtaatc
    16981 caatgaacac tagtcttaaa ctcagcaaac aactcagttt tggagaggag attgctaata
    17041 gcgtgaccca tgctgtgggt gcagtcatca tgcttatctt gctgcctatt tcatccatct
    17101 atagttatga agcacacgga tttttatcct ctatcggcgt ttccattttc gtcatcagtc
    17161 tctttctcat gttcctatca tccaccattt atcactctat ggcctatggt tcgacccaca
    17221 aatatgtttt gcgaatcatt gaccattcta tgatttacgt tgccattgcc ggctcataca
    17281 cgcccgttgt cttgaccttg atgaataact ggtttggcta tctgattatt gtcatccaat
    17341 ggggaacgac catctttggt attctctata aaatctttgc taaaaaggtc aatgagaaat
    17401 ttagccttgc tctttacctg attatgggct ggttggttct ggctatcatt cctgccatta
    17461 tcagtcaaac gacacccgtt ttctggagtc tcatggtaac tggcggactc tgttatacag
    17521 ttggagctgg attttatgcc aagaaaaaac cttatttcca catgatttgg catctcttta
    17581 tcctagctgc gtccgcactt caatacatcg ctattgttta ttacatgtaa aaaagttgag
    17641 aaattcaatc tcaacttttt tctttacaca tattgataaa gtactggtgc aagcgcacat
    17701 catcagtcaa ttctggatga aaagaactta ccaacatatt tttttcttgg gctgcaacaa
    17761 tttgattgtt cactgttgct agaatttcta caccctcacc aacactactg ataatcggac
    17821 cacggataaa ggtcattgga atcttgccaa ctcccttaca ttctgcttcc gtgtagaaac
    17881 ttcctaattg gcgcccataa gcattacgct cgaccaccat atccatagtt cctagatgac
    17941 tctctttctg agaagtgatt tccttagcca gcaaaattaa gcccgcacag gtcccaaaca
    18001 ctggtaagcc agatagaatg ccttctcgga tgggaagtag catgttctgg tcacgtaaga
    18061 gcttgcccat ggttgtagac tcaccaccag gcaaaatcaa acccgacaag tcactctgat
    18121 cttgctgaaa atcatctaga tttctgagtt ctacactctc gacacctaat tgatctagca
    18181 cttttgcatg ttctgcaaag gccccttgca aggccaatat tccgattttc atctattttc
    18241 ctcgttcagc catgagaatt tggatttcat tttcattaat accaaccatg gcttctccta
    18301 aatcttcaga gatttgagct aggatttgag gattacggaa gttagtcaca gccttaacaa
    18361 tggcactcgc tcgtttaaca ggatctcctg acttgaaaat acctgaaccg acaaagaccc
    18421 cctctgcccc taattgcatc attaacgcag catctgctgg cgttgcaaca cctccagcag
    18481 cgaaatttac aactggcaat tttccatgtt catgaacata ttggaccaat tctacaggga
    18541 cttgcaaatc cttggcagca acataaagct cgtcctcacg taagttttga atgcggcgaa
    18601 tttcctgatt catcatacgc atatgacgaa cagcttggac gatatcccct gtccctggtt
    18661 ctcctttggt acgaatcatg gaagcacctt cagcgatacg acgcaaggct tcacccaaat
    18721 ccttagcacc acagacaaaa ggaacttgga attctttctt gtccacatgg aaacggtcat
    18781 cagctggaga tagaacttca ctctcgtcga tataatcaat ttcaatagcc tctaaaatct
    18841 gagcttcaac aaaatgcccg attctgacct tagccattac tggaatacta actgcttctt
    18901 ggatttcctt aatcatcttt gggtcgctca tgcgggaaac tcctccagct gcacgaatat
    18961 cagccggaat tcgttccaag gccatcacag ctgccgcacc agcagcttct gcgatacgag
    19021 cctgttcagg attctgcaca tccataataa caccaccctt gagcatctgt gccaagtttt
    19081 tatttagttc ataacgattt tcagtcattt gttttatcct catcatttgt attggtagct
    19141 accttttcat tttaagtcag aacagaatga agcacaagat aaaaaaacta taattgtatg
    19201 gggacagatt agctaaaaac tatctgacct taacttaagg ccagatagct cattcatttt
    19261 tatttttcag ccgtaagggc agccattgtg atgtagttgt atggtttgtt gaagtgtggc
    19321 aagaagaaga ggtctgtcaa tgccaattta tcaattgtca catgctcttg gatagcaagt
    19381 gagaacatgt ggattcccat gctaattgca atatcatgtg aaaccatttg ggcaccaaga
    19441 atttcacggc tatctttgtc aaagacaatc ttaattgcta cttcatggtt gtcatgtttc
    19501 atgaattctg gtttttgaag atcgttaaag cctgtttcag ttgcgttgta accagcagct
    19561 ttcgcttttt caagagtcaa accagttgaa accatgtgaa gaccgtagat tgagatacca
    19621 tttgaacctt gaacaccgat tccttccaat tcatgtccac aagcgttgta ggcaccaacg
    19681 ataccagtgc gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt acgagcattg
    19741 tcataaacag tcgcacagtc accaacagcg taaacgcctg ggatagatgt ttcttgtttc
    19801 ttgtctacaa ggaaggcacc gttgcggaag agttcgatct taccatctgc aagggctgtg
    19861 tttggacgga aaccaactgc aaggataacc atatccacgt caaagctttc tttgtcagta
    19921 atcaagcgtt caactttacc gtcaccttcg attgctttaa cagtttgacc tagagccaag
    19981 cggatgttgt gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt gtcatagtaa
    20041 ccgttcaaga cagtatcaac gatatcaaca aggacaactt cttttccaag acgttcaaag
    20101 gcttcagcaa gttcaacacc gatgtaacca ccaccaacaa cggcgatacg gtcgaggtgt
    20161 tggctcttgt cagaaagttt attgataact tcttcagcat tttggtacaa tttcacgaat
    20221 tgtacgtttt caagagttgc tttaaattcg cggtttcctt taacaatttc aacaccttcg
    20281 attggtggca agattggtgt agaacctgta gcgaaaatca atttttcgta tgattctttg
    20341 tgctcttttc cttcaacttc cgctgtaact actttgttat catagtcgat tgaaagaaca
    20401 ggtgagttca tgtaaacttt agcaccttta gcttccaatt tttctttatc agaatagaac
    20461 aagccttcag caccgtcaat ttgttcacca atccaaagag ccattccaca tcctaggaaa
    20521 gagatgttag agttttggtc aaatacaaca atttcgttct catttccaaa attatccaac
    20581 atggtattga tacatgctgt accagcgtgg ttagcaccga ctacaacgat tttactcata
    20641 aaaatttcct gccttcattc taaatttacc ttactagtat accatttacc gttagcgttt
    20701 acaagggggg tactattatt tcagcatttt ttatcaaaaa taattcccca tttatcctgt
    20761 tttcaagcct catgaatttt atgagtatat ttcttgactt tttccaaatt ttgtttttga
    20821 aaattctaac tttatggtat tataataaca tgaaaatgaa atgtaagggc ttcaatttag
    20881 atgattattt gatattacaa cttattttct ataagagaaa ggagttggta gcttgactct
    20941 tcgttcacat tctgaacggc taatggggac tactatcact atttcattag tggatgagca
    21001 agccgatatc tttctccaaa aatcctttga cttgctcaaa gaacttgaat accgcttcaa
    21061 cgccaatagt caagaatctg agttgatgga aatcaattat caagcaggaa tagcccccgt
    21121 cacggttcat ccagacctgt ttgagctgat ttcacttggg ttagagcata gcctagcgct
    21181 ctctagccac ctcaatatca gcattggtcc cttaattcaa acctggcgta tcggtttttc
    21241 agatgccaag gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa tcaatcctca
    21301 tggtatcgag ttagattctt ctacttctac tgtgttttta aaacagaaag gaatgaagat
    21361 cgatctaggt tgtttagcca aaggatacag tgcggataag gttgcccaat ttcttaggaa
    21421 agagggggtg acttctgcct tgatcaatct gggagggaat atcctgacca ttggaaaaaa
    21481 tcaggcaaga ggggataacc catggcaaat cgggattcaa gacccagcca atcctagggg
    21541 aaatcattta atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag gcatttatga
    21601 acgtcacctg accgtcgatg gacaagatta ccatcacatt tttgacagtc aaacaggata
    21661 tcctgttgaa acggaactag cgagtctaac aatcatctct gataaatcag tcgatggcga
    21721 aatctggacg actcgactct ttggagaaag acctgcttct atcctctggc aagtcgaaag
    21781 tttggaaggc atcgaagtca tcctcatcga taaagaaggc cacctaagct gttcttcagg
    21841 aattcctact ctatagagac aactgtttca atggaatttt aaaattgtat tatgtaaaaa
    21901 gagaaaggaa atctcatgtt aaaacttatt gctattgttg gaacaaattc aaaacgttct
    21961 acaaaccgtc aattgcttca atacatgcaa aaacactttg ctgacaaagc tgaaattgag
    22021 cttgttgaaa tcaaggccat tcctgtcttc aacaaaccag ctgacaagca agtacctgct
    22081 gaaatattgg aaattgctgc taaaatcgaa gagacagatg gcgttattat cggtactcct
    22141 gagtatgatc actctattcc agctgttttg atgagcgctc ttgcttggtt gtcttatggt
    22201 atttacccac ttttgaacaa accaatcatg attacaggtg cttcttacgg tacgcttggt
    22261 tcatctcgtg cccaattgca acttcgtcaa atcttgaatg ctcctgaaat caaggcaaat
    22321 gttcttccag atgaattctt gctctcacac tctcttcaag catttaaccc aagtggcgac
    22381 ttggttgacc ttgatgttat caagaaattg gatgccatct ttgatgactt ccgtatcttt
    22441 gtaaaaatca cagaaaaatt acgtaatgca caagaattac ttcgcaaaga tgctgaagac
    22501 tttgactggg aaaatttgta agataggaga ccaaaaagaa tgaaatttgt tggacttgtt
    22561 ggatcaaact acgatcaatc atataaccgt aagctcttgg aatttatccg tcgctacttc
    22621 aaactcaaat ttgaattaga agttcttgaa attgacgaag ttccaatgtt taaccaagat
    22681 gaaaaatggg atgaaagttt ccaattacgt tatttatata acaaaattac tcgtgcagat
    22741 ggtgttatca ttgctactcc tgagcataac cacactatct cagcttcact caaatctgta
    22801 cttgaatggc tttcatacga agttcatcca tttgaaaaca agcctgttat gattgtgggt
    22861 gcatcatact atgaccaagg aacatcacgt gctcaagttc accttcgtaa aatccttgat
    22921 gctccaggtg ttaatgccta cacgcttcca ggtaacgaat tccttcttgg taaagctaag
    22981 gaagcttttg ataacaacgg aaatatcacc aacgaaggca ctgttaaatt ccttgaaact
    23041 tgcttagata actttgttaa atacgtagga gtcgtttcga aattgaaaaa accaaaacca
    23101 atcgaatcag aagacttgga ttgtggaaaa ccaatcgcta caaccatcac agaagttgac
    23161 cctgacgatc cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt ttctggtgat
    23221 acctatgtca aattggacca cggtatccta acagttaacc aaattgatat gttcttgaaa
    23281 gctatgccat ttgaattgac atacgctgac gataacaacc aattcctcta ctacaacaac
    23341 gctcaccaag atccagacac tatgttcgct aaacgtgtac cacctcaatc aggtagccgt
    23401 atgtcgactg ttcatggttc tcttccacca gcacgtatga agaacgtaga gtgggttatc
    23461 ggaacacttc gcaacggaaa ccaagaatac gtccgtacga tcgttccagg ttctcctgca
    23521 ggtgttatca acactcacaa ctaccaagca atgtactatc ctgatggatc atacgctggt
    23581 atcaatgaaa tcgtctttaa cttccaacca tggcttgact ggtacctaaa agagactggt
    23641 caacgtttgg tgggtggtag cggaccattt gctcctgctg ccggaggtca tggagacgcc
    23701 gatgctactt ctggcgcttc tgattcaggg gatgctggag gccacggtgg tgacgcagac
    23761 gctacagccg gtgcaagtta ctaatgatag tttttaggaa ccattatggt tcctttttta
    23821 gcgaaaaaag actagcaaac acaaactgct agtctctttg ttatcgtttc atctatcctt
    23881 gttaaaagaa agaatactta tactcaatga aaatcaaaga gcaaactagg aagctagccg
    23941 caggctgtac ttaagtacgg caaggtgaag ctgacgtggt ttgaatttga ttttcgaaga
    24001 gtattattat gaatttgggt catcaagact acggccatgt aatccttttt cacgttgtac
    24061 ttggcgtagt ttttctggtg taacatcgtt tccttcttcg tccacaattt tgattccttc
    24121 aatgtggtga cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta gtttggcttg
    24181 ttccactttt tcttctggtg ttaagccttc tgtttttttc tttttagcaa gctcattgat
    24241 acgagcaatt tttttcggat ccatttcttc tcctctgtaa taagataaag tccgtttatc
    24301 aaattttatt tagtgttaat ttggttaaaa caagcaaact tagctgcttt cttggttagt
    24361 tgtgacaaga ttgccaaacg attttgacgg acagcctgat cttcagccat taccatagta
    24421 ttttcaaaga aagcatcaat gactgggcta agcgcaaaga gttgtttcaa ttgctgactt
    24481 gcaggtcctg ataaaacgag tgtttctact gcttctgcca aagctttttc ttggtcattc
    24541 tcaaatagtg ctgaatcaac cgtagcaacc ccttctgcct tctcagccag gttaaaggca
    24601 cgagaaagtg attcaacaga tggtttaaaa tcttcttcct tgcttacttc tacgagagca
    24661 cttgctgctt ccaacatatc tgccacaaca aagtttgaac ctgcaagaac tgcttctttg
    24721 atatcttttg gagtagagcc catcatctta tcaacacgag ccttgataaa gtccataacc
    24781 tctgctttat tttcataagt caaactgtca aatttcaatg cataaaggct atcaatcagc
    24841 tcatccatag caatgtgcca accaaaggca tccaagatac gaaccacacc ttgagttgca
    24901 cgacgaaggg cataagggtc attagaacct gatggaatca atcctactga gaagaaactc
    24961 aaaatcgtat ccaatttgtc tgcaatggct agaactgcgc cgaccttgct ctctggaagt
    25021 tctccttcag ctgatgtagg catgtagtgt tcacgaatag cagctgccac cgctggagtt
    25081 tcaccagcaa gaagggtgta tttttcaccc ataattcctt ggagttcgtc aaattcacca
    25141 accatacctg tcaacaagtc aaacttgtaa atggctgctg cacgagcaag gtcaactgtt
    25201 tcatccactg acaaaccagc tttttctgcc aaaagtacag tgatttgacc cgtacgaatc
    25261 atgtgttcac gaagggaacc aatcttctca tggaaggtga cattgtttaa tttttcaaca
    25321 agatctgaaa tcaccaattt ttggtcttca cgccagaaga attctccgtc ttccaagcgg
    25381 gctaccaaga ctttttcatt tcctttgatg acatttttca aacgctctgc gtttccgtta
    25441 cgaacagaaa tgaagtttgg caagagtttt ccatcttgat cacgaacaac aaagtaacgc
    25501 tggtgttcct tcatagaagt caccaagact tcttctggaa cttcaaggta tttagcatca
    25561 aaacttccca tgaaggcagt tgggtattca accaaattca agacttcatt cagcaaatcc
    25621 gcatcaattt cgatacgtac accatgtttt gcctcaattt ccttgatttg gtcaacaatc
    25681 atttgctcac gttcacatgg atctgcgatt acaaactgct tacgaaggtc ttcttcatag
    25741 ctcaatgctg actgaatttt ggtttctttc cccaagaaac gatggccacg gctcacacga
    25801 cttcccttga tatcaaggaa atccaagtca aactcttgct catccaagag aacagttaaa
    25861 gtgtggacag ggcggatgta ttcaaagcta tttccagccc agtgcatgct gacagggaaa
    25921 gtcaatgact tcaagacatc tacaacacca ggaacaatgg cttcaactgc ttgaccaact
    25981 tcttccttag tgacatagac atattcttca cccttgattt cacggaattc gatatcttca
    26041 acagtcaagc cttttccacg gacaaatcct tgagctgctt tggtgaagtt tccatcacta
    26101 tccaaggcaa ttttctttgc tggtcccttg aaatcttctg tcaaatcaga ctgtttgtct
    26161 gataaaccag tcacacgaac agccaaacga cgtggtgttg agaaggtttg aatggcttca
    26221 aaagacaggc ggttttcctt gaggaaggct gccatttttt cgcctagttg tttttcactt
    26281 ggtgtgacaa cataggctgg taattcttca agaccgagtt ctactaataa gttttttgtc
    26341 atgttttttc tccgaaaagt atctttttat tttccagttt gccttatgtg attggcacgc
    26401 aagcaaccaa cttcgttgtt tcattgctaa aattggagcc aaaagtctcc aattttgcct
    26461 agtatcctta gtttcactaa ggataccttc atcactgcgg caactggctc agggctcact
    26521 ctgttcgccc attttcgtaa tttgtcactc tctttattct gcgtcttctg ctaaaagttt
    26581 aactcgtgtt tcttcatcca aaagtgggta acctaggcgt ttgcgttctg caacaaaggt
    26641 tttggctaca acacgggcca agttacggat acgagcgata tagcctgcac gctctgttac
    26701 agatacggca ccacgcgcgt caagcagatt aaaggtatgt gaacatttga gaacatagtc
    26761 ataggcaggg tgtaccaagc cttcttctaa tgcacgacca gcttcttttt caaacttatc
    26821 aaagttttca agcaacattt cttggtccga aatttcaaat gaatattttg agtgctcata
    26881 ctcaggctgg ataaagattt ctccgtattt tacaccatca gcccactcga tatcatagac
    26941 agagtctact tcttgaatgt aagaagccaa gcgctccaaa ccataggtaa cttccgcagt
    27001 cacagggcca gttgccaatc caccgacttg ttggaaataa gtgaactgag tgatttccat
    27061 tccgtcaagc caaacttccc aaccaagacc agctgaacca gttgatgggt tttcccagtt
    27121 gtcctcaaca aaacgaatat cgtgctccaa aggattgatt cccaattttt ccaaagactc
    27181 aaggtaaagt tcttggatat ttgatggaga aggcttcatg accacctgga attggtggtg
    27241 ttggtagaga cggttagggt tttccccata acgaccgtca gcaggacgac gtgatggctc
    27301 tacataagct gcattccatg gctcaggtcc gatagcacga aggaaagtgt aaggactcat
    27361 tgttcccgca cctttttcat tatcataagc ctgcataagc atacaacctt ggtcattcca
    27421 aaattgttgc aaagtcaaaa taatttcttg aaatgttaat ttcttagaca ttgaatactc
    27481 cttaataaaa aataattact tgcgacacga gtctgcctcg tcgatcatac gaggcaagac
    27541 gagttagtac tgcgtctagc tcaggcactc tagtgctgag cgtggggcag tccgactgta
    27601 aggaggtttc tgccactgat gcagtgaaat gttaatttct cagacattga atactccttt
    27661 agtttttata tttctttttc aattaatttc tgctgaacaa accaatctaa caagggaaaa
    27721 gttttttctg tatttgccca taaatgataa gaatcaaaga ccgcttgtac actacctaaa
    27781 ttttctacca acttatctac tgtcaaaaag ctgcgccagt attcataaaa aatacttgca
    27841 tagttcttat cataagtcga agaaccaaaa tcattcaatg aatgccaacc atacttcttc
    27901 tgaaaaagtt ctacgagaga ttgattacaa attttttccg cttgaaattc ctcttctgtc
    27961 aagaaatact tgcgactaat atattcaacc atcccctctt cgaaccagat ataagagtca
    28021 taaccatcaa aatcatctaa aaaatgctcc gaccaatgag ctaactcatg tcctacaatc
    28081 tgtaagagga aattttcaga taaagaatga tagtggcttt ctattgcttg agtttgctca
    28141 gaacactcgt agtccatcaa ctgatacaaa tacaactctt tccaaacagc taaatcaggc
    28201 gtcataacca ttcgtctatt atttgtatag gctggaacag cactttccct aataatctgt
    28261 gtagcagcat taagatctga ccaaataacg gcttgcggta aatcacagac tgcaagttca
    28321 ttctttaaaa aagattgata atctttcaac ttttcagtat ttcttactac aaaatcacga
    28381 aatgtagcta gttgactatc gtcttttaca agataaaggt tgtccacggc tctcctttct
    28441 ttcacacaat agactgaata agcaaaagaa ccacatctga caagcctagg ttgatttaac
    28501 ctaggggcgt cagaaacgcg gttccaccct aatttattac ttcattgttt ttgaaaatac
    28561 tacagaaagc gccagcccat tattttgccc tacttggctc ccactgtccc aagctcgctt
    28621 gaagaacgcc ataagacttt ctttcctgct gactattata tcaaaaatta gaataatgta
    28681 caattctttt tatgattttc tagaaatcca catcatcaac tcgtggagca cccaattgaa
    28741 cagcaatcgt ttttaaggtt tctctctcct tatgactcag ttcaattcca aagcaatcaa
    28801 gattagcctg aatacgagag attgtgatag attttggaag tggtaaaaat ccttctgcca
    28861 agctccaggc caaggctatc tgagcaaccg attttccgtg atttgctgct atttcttgga
    28921 cttgcttgct atcaaacagt tctccttgtc caaaaggccc ccaagcttcc aataaaattc
    28981 ccttttcacg acagtaagct acgacttgat cttgatacac acctggcgcc aagcgaactt
    29041 gattgaccgc aggaacgata gttgcagttt caagcaaggc atccaaatga tggggaagaa
    29101 aattgctaac gccgatagca cggattttcc cttcttgata gaggtcttcc atcgctctcc
    29161 aaacttccgc attgcgagtt ttccatgcgt cattttctct gagcggtttt gggttcggcc
    29221 aatgaatcaa atacaaatcc aaataatcca agcccagttt ttctatagat ttttccaaag
    29281 cttgacgagt ttgctcatag gtttgctgac tattccaaag cttggtagtt acgaacattt
    29341 cttcacgtgg aactccgcta tctttgattg cttgaccaac actttcttca ttctgataaa
    29401 tcgccgccgt atcaatatga cgataaccag ccttcaaggc ttctaacact gcacgatagg
    29461 cttcttctcc atccttagcc ttaaaagttc caaatcccaa tactggaatt tctactccat
    29521 tatttaattg ataggtattc atatgcttct ccttctattt tattcatcaa ttatagcata
    29581 aaacattttt taagtagtac tatcttctgt aaaaaataag tctgtcaaat atctaacaga
    29641 cctatttttt cttgcttatt catcacgact atagtacagc tcatgagctt ttaggcgagt
    29701 attgagcatc tctggtatgg tcacaaaggt ataaccttga tttttcaaat actcaatgac
    29761 ccttggcaag gcattgactg tcggactgtg aatatcatgc atcaaaacga tagagccgtt
    29821 agctacttga tgctgaattt ctgtcaaaat agatgcttca tttttactct tccagtccag
    29881 actatccaca tcccacatga taaagctcaa atccaagcta ttgcgaatat catctgtaat
    29941 agcaccataa ggtggacgca tgagtttaga actagaaccc agcactttag ttagcacatc
    30001 ctcagtatca gtaatctgct ttttagcttc atcaagagag agttgcgaga gaatcggatg
    30061 gctccaacta tggtttccaa caacatgacc ttcagatttt atcctcttca ccaagtcctc
    30121 attcccagaa acatttttcc caagcacaaa gaaagtcgct ttaatatcat atttagctag
    30181 ggtctctaat acctgcgggg tcgttgctgg atttggacca tcatcaaagg ttagagcgac
    30241 aactttttga tatttcttat caaagtaaga ttggtacaag gccgcatctt tttcgagtaa
    30301 gtacgaagat tggataacat caaagaaagc agatactggc aaggctatct cttctaaatt
    30361 ttcaaccaca ggacttggat aaaggataat ctgactatcc ttgtaatcaa aattccatgc
    30421 agacaagtct tggtcagaga agttttttac aatctgctca ctctggtctt gctctatttt
    30481 tttatcctct atgaaggagg tcaactcttt tatcagctgt tccttagcct tactagcatc
    30541 tgaaaacagt tggtcaagtg taaaaggttg cccatcttct gttaagtgaa cctttcctag
    30601 actggtcttt tcagtctctt caatcttaaa agcaactaaa tcatagattt gtttggtcac
    30661 attacgatta acgactccct ttaaacctga ctcttcttgc tctgtatagt agaaaacaag
    30721 attgtcctta ctttctagct tgtccttaac atcttgattt atcagctccc taacagagga
    30781 aatcactttc tccccttgga gaggataata ggcaatcact tcggcttgcc cctgacgaaa
    30841 atgctccttc tgatttccct cactcaattg atcatctttc tcttttttga gcgattcaat
    30901 cttttgctca aaactttttt gctggtagat cttaaaagca ataaatccgc ctaataggca
    30961 aatagaaatt gctaaaatac caatcaaagc caataataca tgtctcgttt tcccgtgtct
    31021 gccacgtcct agtctacttt tattcatatt tatatcataa caaatttgag caataatttc
    31081 aatgatacaa tttggcaatc cacaattcct ctagcaagcc aaagcatctt acatcaactc
    31141 caacatccgt atctgtagag attatgtagt tttctatcta tggaatttct agtagattga
    31201 agctagaata gtagacctat acttctaaaa cattgttaga aatcgatttt actgtcctga
    31261 tcgatttgtc ctattctcat ttcattttac tataaaacta tgaaaagcta ggtcatctga
    31321 gaagtaatta ctatcgacaa ttgcgatagc gtatactggt gcgatttgtt tgtagctctg
    31381 gtgggtatca ccttaacgtt ggcgaatttt ttctaggttt tgattaacct gactgcacag
    31441 ataagcccat aggcgattga tgaaaaaatt ctgatgatga atctgaattt cgatgataac
    31501 ttggattcca ttatctaact ccgccaagac gtctatacta gtatagaaat cctgcactga
    31561 gtagggcatg gaaggcaaga cgtgaatgtt acttccctcc aaaatcgtca cattttttgc
    31621 tggcaagtcc agcatatcgc agataaattg acaaatcatt agttgggctg atacccggat
    31681 gtctgagaat cctccttttc ctccttctat tatagcacat ttttaaatct aggtttgcta
    31741 gattctatgc ttctatctat ttattcggaa aaaaaagctt ttcttcagaa gaaagctaat
    31801 agcttatttg aaattttctc ctctctgttg gatagtcccg tctatctatg ttataatgaa
    31861 agaaggattt aaaatcggaa aaggagtatt tatgctaaaa ttaggtgtca tcggaactgg
    31921 cgctatcagc catcatttca tagaagcagc ccataccagt ggagaatacc aactggtcgc
    31981 aatctattct agaaaactag aaactgcagc aacctttgct tctcgctatc agaatatcca
    32041 actattcgat caattagaag tcttcttcaa atcttctttt gatttagtct atatcgccag
    32101 tccaaactcc ttacattttg ctcaggcaaa agctgccttg tctgctggta aacatgttat
    32161 tctcgaaaag ccagctgtca ctcaaccaca agaatggttt gatttgattc aaacagctga
    32221 aaaaaataac tgttttatct ttgaagcagc tcgtaattac cacgagaaag cctttactac
    32281 tatcaaaaac tttttagcag ataagcaagt gttaggagca gatttcaact atgccaaata
    32341 ctcttccaag atgcctgact tgttgactgg acaaacacca aatgtctttt cagaccgttt
    32401 tgctggtgga gccctcatgg atttggggat ttatcccctc tatgctgctg ttcgtctttt
    32461 tggaaaagcc aatgacgcga cttaccatgc tcaacagctt gacaatagca ttgacctaaa
    32521 tggagatggt atcctcttct acccagacta tcaagttcac atcaaggctg gaaaaaacat
    32581 cacttccaat cttccttgcg agatttatac aacagatgga accttgactc tcaacacgat
    32641 tgagcatatt cgctcagcta tttttaccga ccaccaagga aatcaagtcc agcttcctat
    32701 ccaacaggct cctcatacga tgactgagga agtcgctgca tttgcacaca tgatccagca
    32761 accagatctg aatctctacc aaacttggct gtatgatgca ggctctgttc atgagctact
    32821 atataccatg cgccagactg ctggcgttag atttgaggca gaaaaatgaa aaccaaacta
    32881 ccgactgaat ggcaagaact gagtgaccaa ctcggtttcc aagaattcac ccccattcaa
    32941 actcaactat ttgagctcct tcttgctgga gaaaacctcc taggagtgag ccaaaccgga
    33001 actggtaaga ccctagcgta tctcctacca agtcttctca gactacaaaa gaaaaaagcc
    33061 caacaactct tgattctagc accaaacacg gaacttgctg gacagatttt tgatgtatgt
    33121 aaaacgtggg cagaagctat cggattgact gctcaactct tcctttcagg ttcaagtcag
    33181 aaacgacaaa ttgaacgtct taaaaagggg ccagaaattc tgattggaac tcctggccgt
    33241 atctttgaac tcattaaact taaaaaaatc aagatgatga atgtggaaac catcatcctg
    33301 gatgaatttg accaattact agatgattct cagattcact ttgtagagaa aatcactcac
    33361 tacgcacctc gtgaccacca actggtctac atgagtgcca cgaccaagtt tgaccaagaa
    33421 aagattgtgc cgaatacacg cactattgat ctctctgatc aaaaattgga caatatccag
    33481 catttctaca tgcaggtaga ccaacgtcat cgagtggata tgctacgaaa actggctcat
    33541 gtagaggatt tccgtggtct agtcttcttc aatagcctgt cagaccttgg gaatgccgag
    33601 gaaaaactac agtatcgtga tatattggct gtttccctcg ctagtgatgt taatgttaaa
    33661 tttagaaaaa tcatcttaga aaagtttaaa gataaccaac taaccctgct tcttgcaact
    33721 gaccttttgg ctcgtggaat tgatatcgat agcctagaat gtgtcgtaaa ctttgatatt
    33781 cctagagata gcgaaaccta cacacaccgt gctggccgta ctggtcgtat gggcaaggaa
    33841 ggttatgtta tcactctcgt cactcatcca gaagaaatca aaaaacttaa aaagtttgca
    33901 agtatccgag aaattgtcct aaaaaaccaa gaactctata tcaaataaag ccccattgct
    33961 ctatacacat ccagtgtatg gagctttttt ataagcaatt caattttata ctcatctgct
    34021 ttcaaaaagc attctagtcc atctccgatt aacgatggac tttatcacct ccttctccaa
    34081 tccttgtatg acatcttgaa gttgattcat gacatcttcc aaaattcgaa aggctttatt
    34141 cttaaatcca cgtttacgaa tctctttcca cacttgttca atggggttca tctctggtgt
    34201 gtatggagga ataaatgcaa aaccaatatt agtcggaatc tttaagatac ttgatttatg
    34261 ccatatagca ttgtccataa cgagtaaaaa ataatcatct ggataagctt gtgaaagctc
    34321 ttctaaaaag gcgttcatcc actcagtatt acatctacca gctattaaga aaaatgattc
    34381 gcctgtatgg gcatcaacag ctccataaca atagcgaaat tctcgtatat agtgactatg
    34441 ga
//
LOCUS       DAVMCG010000018        33900 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVMCG010000018 DAVMCG010000000
VERSION     DAVMCG010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.018"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..363)
                     /locus_tag="VYP66_001070"
     CDS             complement(<1..363)
                     /locus_tag="VYP66_001070"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850633.1"
                     /translation="MSPGTFIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLALIF
                     LIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVYIFLGYVLVIQKDVYLFSIL
                     IIFSNFSVPFIREKEYELF"
     gene            complement(460..798)
                     /locus_tag="VYP66_001071"
     CDS             complement(460..798)
                     /locus_tag="VYP66_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1850634.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKIKGTRITK"
     gene            1264..2127
                     /locus_tag="VYP66_001072"
     CDS             1264..2127
                     /locus_tag="VYP66_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850635.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRRIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            complement(2528..2908)
                     /locus_tag="VYP66_001073"
     CDS             complement(2528..2908)
                     /locus_tag="VYP66_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HEV1850636.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVDL
                     AIYSGGATIYSADAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGVDWADGSLDGYIFA"
     gene            3672..3992
                     /locus_tag="VYP66_001074"
     CDS             3672..3992
                     /locus_tag="VYP66_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1850637.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(4281..5672)
                     /gene="argH"
                     /locus_tag="VYP66_001075"
     CDS             complement(4281..5672)
                     /gene="argH"
                     /locus_tag="VYP66_001075"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1850638.1"
                     /translation="MAKNTKLWGGRFEGTVEDWVERFGASISFDQKLAKFDLIGSLAH
                     VQMLGQTGILSLEESEKIQAGLKELLEELEAGQLDFDIANEDIHMNMEVLLTEKIGPL
                     AGKLHTARSRNDQVATDMHLYLKEQLGHVLDKLVHLKGVLLDLAENHVETIMPGYTHL
                     QHAQPISFAHHLMAYYNMFQRDSERFEFNQKHTDLCPLGAAALAGTTFPIDRQLSSDL
                     LEFKKPYTNSLDAVSDRDFILEFLSNASILMMHMSRFCEEMINWCSFEYQFITLSDTF
                     TTGSSIMPQKKNPDMAELIRGKTGRVYGNLFGLLTVMKSLPLAYNKDLQEDKEGMFDT
                     VETILNSLDVLAGMLSSLQVNKEKMQESTEKDFSNATELADYLAGKGLPFREVHEVVG
                     RLVLDSIKSAKNLQDWTLEELQTYHSLITEDIYVYLQPKTAVQRRNSLGGTGFDQVEY
                     QIAVAKKANEAKK"
     gene            complement(5701..6897)
                     /locus_tag="VYP66_001076"
     CDS             complement(5701..6897)
                     /locus_tag="VYP66_001076"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEV1850639.1"
                     /translation="MSKEKVILAYSGGLDTSVAITWLKKDYDVVAVCMDVGEGKDLDF
                     IHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVE
                     IAHQTGATTIAHGCTGKGNDQVRFEVSIAALDPNLKVIAPVREWKWSREEEIHYAKEN
                     GVPVPADLDNPYSVDQNLWGRANECGILENPWNQAPEEAFGITSSPEAAPDMPEYIDI
                     EFSEGVPVSLNGEVLKLADLIQKLNEIAGKHGVGRIDHVENRLVGIKSREIYECPGAV
                     TLLTAHKEIEDLTLVREVAHFKPIIENELSNLIYNALWFSPATQALIAYIKETQKVVN
                     GTAKVKLYKGSAQVVARKSPNSLYDENLATYTSADTFDQDAAVGFIKLWGLPTKVHSE
                     VQKSAK"
     gene            complement(6914..7720)
                     /locus_tag="VYP66_001077"
     CDS             complement(6914..7720)
                     /locus_tag="VYP66_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1850640.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQNGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKKSGELDKLIEDAFKASIEK"
     gene            complement(7927..8568)
                     /locus_tag="VYP66_001078"
     CDS             complement(7927..8568)
                     /locus_tag="VYP66_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850641.1"
                     /translation="MIELENITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSATLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            complement(8565..10673)
                     /locus_tag="VYP66_001079"
     CDS             complement(8565..10673)
                     /locus_tag="VYP66_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1850642.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRHFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSLPLLVLIFFAHALLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(10725..11012)
                     /locus_tag="VYP66_001080"
     CDS             complement(10725..11012)
                     /locus_tag="VYP66_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1850643.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            11438..11758
                     /locus_tag="VYP66_001081"
     CDS             11438..11758
                     /locus_tag="VYP66_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1850644.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(11810..12397)
                     /locus_tag="VYP66_001082"
     CDS             complement(11810..12397)
                     /locus_tag="VYP66_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1850645.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            12639..13310
                     /gene="sdaAB"
                     /locus_tag="VYP66_001083"
     CDS             12639..13310
                     /gene="sdaAB"
                     /locus_tag="VYP66_001083"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1850646.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMNTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            13319..14191
                     /gene="sdaAA"
                     /locus_tag="VYP66_001084"
     CDS             13319..14191
                     /gene="sdaAA"
                     /locus_tag="VYP66_001084"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1850647.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            14213..14845
                     /locus_tag="VYP66_001085"
     CDS             14213..14845
                     /locus_tag="VYP66_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1850648.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(15103..16953)
                     /locus_tag="VYP66_001086"
     CDS             complement(15103..16953)
                     /locus_tag="VYP66_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1850649.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(16992..18152)
                     /locus_tag="VYP66_001087"
     CDS             complement(16992..18152)
                     /locus_tag="VYP66_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1850650.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNMLQ"
     gene            18210..19376
                     /locus_tag="VYP66_001088"
     CDS             18210..19376
                     /locus_tag="VYP66_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1850651.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            19515..19841
                     /locus_tag="VYP66_001089"
     CDS             19515..19841
                     /locus_tag="VYP66_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1850652.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            19828..20421
                     /locus_tag="VYP66_001090"
     CDS             19828..20421
                     /locus_tag="VYP66_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1850653.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            20414..21325
                     /locus_tag="VYP66_001091"
     CDS             20414..21325
                     /locus_tag="VYP66_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1850654.1"
                     /translation="MRKWTKGFLIFGVATTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSANHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            21388..22452
                     /locus_tag="VYP66_001092"
     CDS             21388..22452
                     /locus_tag="VYP66_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850655.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEERAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIEAPEDSEARTGIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISTLVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(22523..23383)
                     /locus_tag="VYP66_001093"
     CDS             complement(22523..23383)
                     /locus_tag="VYP66_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEV1850656.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLESLPSAFYHQLDANQLEVQPILG
                     QDFKTLAQEK"
     gene            complement(23658..24644)
                     /locus_tag="VYP66_001094"
     CDS             complement(23658..24644)
                     /locus_tag="VYP66_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1850657.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(24916..26391)
                     /locus_tag="VYP66_001095"
     CDS             complement(24916..26391)
                     /locus_tag="VYP66_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1850658.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEVLNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(26475..27398)
                     /locus_tag="VYP66_001096"
     CDS             complement(26475..27398)
                     /locus_tag="VYP66_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1850659.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(27412..28341)
                     /locus_tag="VYP66_001097"
     CDS             complement(27412..28341)
                     /locus_tag="VYP66_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1850660.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYSLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(28660..28881)
                     /locus_tag="VYP66_001098"
     CDS             complement(28660..28881)
                     /locus_tag="VYP66_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850661.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLF
                     LADEKGSEHTEAEVIDNLKEVIAKLKANA"
     gene            complement(28835..29095)
                     /locus_tag="VYP66_001099"
     CDS             complement(28835..29095)
                     /locus_tag="VYP66_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850662.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            29175..29312
                     /locus_tag="VYP66_001100"
                     /pseudo
     CDS             29175..29312
                     /locus_tag="VYP66_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(29416..29571)
                     /locus_tag="VYP66_001101"
                     /pseudo
     CDS             complement(29416..29571)
                     /locus_tag="VYP66_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(29757..30368)
                     /gene="rpsD"
                     /locus_tag="VYP66_001102"
     CDS             complement(29757..30368)
                     /gene="rpsD"
                     /locus_tag="VYP66_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1850663.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(30563..31615)
                     /locus_tag="VYP66_001103"
     CDS             complement(30563..31615)
                     /locus_tag="VYP66_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1850664.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(31612..32310)
                     /locus_tag="VYP66_001104"
     CDS             complement(31612..32310)
                     /locus_tag="VYP66_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850665.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(32477..>33900)
                     /gene="pavB"
                     /locus_tag="VYP66_001105"
     CDS             complement(32477..>33900)
                     /gene="pavB"
                     /locus_tag="VYP66_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1850666.1"
                     /translation="YFYQVALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGK
                     PDLDNIVATKKVTININGLISKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKTKGQYFYQVALD
                     GNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTININGLISK
                     ETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKAS
                     DKAPWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQT
                     YSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHN
                     HATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASI
                     GFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT        10155 a         7357 c         6012 g        10376 t
ORIGIN      
        1 aaataattca tactcttttt ctctgataaa gggaactgaa aaattagaaa aaattatcag
       61 aattgaaaac agatatacgt ctttttgtat cactaaaaca taacctaaaa atatatagac
      121 catcaaatct agtacaaaaa gagaaaatat cctccttttc attaccttac ttgccttaaa
      181 gattctgttt aatagaacct ttatcgtagt atctacacaa atttttatca aaaagataag
      241 agccaataca cctgctgctg caccaataag ccaacctcca aggcctccaa ccttaatata
      301 gtttattagt ttttttgtta aaactgcagc tccagtcaat gctataaaag ttcctggact
      361 catagctaaa gctgcgcaaa ttccttgaca agcactcttg cttaaataag ccccccccca
      421 tcaagataca tcatctcctc ttgctcaaga gcaacataat tatttggtaa tacgagttcc
      481 ctttattttc tcctttatac tatgtaatac cacaaaatga ttttgaccta aatcattctt
      541 aacttgaaga atcgcaggaa atgttaattt tggagtcaaa tcttccagtg ctactcgaac
      601 agcttttact gtaaaattca acttattcag acctgaaaca ataccactga cagtcgttcc
      661 atacatgtct gtaccaataa tttcccgaat cttcatgatt gatagttcct ttttgtaaga
      721 taaaagaact gttgaaacaa ctgccgcagc acaatctgac tgatcatgtt gcatcgtaca
      781 aggatatttt tttaacatag aaatactcaa ttctttagaa ttaatctaac ttttctttga
      841 tgtcacccaa acctcaatca ctgcccagta gttcttgaat cagtttagtt tcaatcgtat
      901 cattctttgt tcttgatatc tttccaagca ttgtagtaca gcagattttt gtccaaggac
      961 taagcctcct ttaacaactc aagctccctt acattatatc gaccagcccc atggaaagat
     1021 tatggccaga ctaatcaatg atatcataca tactagaata caaaatattt ttttattcat
     1081 actttttctc ctatctttat tttctaccta catcatacct cttattaagc tcattttaaa
     1141 attacgttaa cttttttcac aaatttattt ttactttctt ttttactttt tacactgcta
     1201 tgatacaata tttttaacaa gattttatta tttgttaact tttttcacag aaaggagaaa
     1261 atcatgcgtt atgatttcgg aaaggtctat aaagaaatac gtgagtcaaa ggggctgacc
     1321 caagaagagg tctgtggggg tgttctctca agaaccagct tatcaaaaat cgaaagtggc
     1381 aagacaaccc caaaatatga aaatatggaa tttcttctcc gtcaaatcaa tatgagtttt
     1441 gaagagtttg aatatatctg tcaactttat caaccaagtc aacgcacaga gattatgcaa
     1501 acctatctca atatgcgttc cattatcggg accagcgatc ttgtcaattt atttcaaaaa
     1561 tgccaagact acctcaagac ccaccacgat ctccctatag aagaaatcag agatatgctt
     1621 gaagttgtca tttatatccg tcaacacggg gcaggggaac tatcagatca cgcagaacag
     1681 gttgtcaaaa aactttggag aagaattgaa aaacaagata catggtatga gagtgatcta
     1741 aaaatcctca ataccattct tttcagtttt cccattgaat acctccatct catcactgga
     1801 aaaatattgc aacgcctaga agtctataaa aactatcaac atttatatga cttgcgaata
     1861 gcaatcctgc tcaacctttc cacactctat ctatacaatc aagataaaaa catgtgtaag
     1921 caaatctgct acactttact ggaggacgcc aagaataaga aaagctacga taggcttgct
     1981 atctgctatg tccgtattgg gatttgtaca gataatgcta aacttatcca aaaaggtttc
     2041 tcactcctag agctgaccga ggaaacttct atgctgtctc atctcaaaaa agaagtagag
     2101 acccattatc aaccaaagaa attataaaaa aagtcgaggg agctcctcga ccttttcata
     2161 gaatcgccga acgatttaac gagaaagtat gacttttacg tttatcccaa ctcaattatg
     2221 acattttttt caaaagtcaa tatatctcac tttttcaacg acaagaaaga ggctgataat
     2281 ctaccaacct cttgttttta aatacatttc aagtccaaac tattctttat agaaaaaagt
     2341 cctataaatt cgagcaatag ttaaaataca aacaaatata attcccaaaa tagataacac
     2401 tattttcaca aaattcattt cagaacctat tatatatacg tgaaaaaaag gggctattcc
     2461 tacacatata tacaataaat aacttacaaa gtttatttca ccaattcctg caaaaaaatg
     2521 tttcatttta agcaaaaata taaccatcta agctaccgtc agcccaatca accccatatg
     2581 cgattgctcc acctagtgaa aatccagtaa cagttagtgc aacgtttagt gcagtattga
     2641 ctaaatggcc agctgcacta cctacatgtt taattattaa actacgtaat gttctcgtaa
     2701 tagcccctct attagctgag atagcttttt ttatcgcatc agcagaataa attgttgcac
     2761 caccactata gatggccaaa tctacatcca gaactgttgc aaaactacct ctactattcc
     2821 accagttacg accaacacca cccccatcaa gatacatcat ctcttcttgc tcaagagcaa
     2881 cataattatt tggtaatacg agttccattt attttctcct tttttattaa gcatggttag
     2941 gatggtttcc taacaagtga tcgcaggctt tgtttagtta cctaaattag acttccttcc
     3001 tttatcttat tttaaatatt taaaaccagt tactgcttga agcttaacag tttacttaat
     3061 tcaaataaca gctaatcact gattccctga ttttatcaaa tatactaata acaacaattg
     3121 tgatacgatc atcattataa gaacaacatt taacgaatca aagtttttcc gagataataa
     3181 taaagcaaca gcaagcagta ttattactaa agattgaata actactatta ctcttaacat
     3241 tttatcctcc actaacaact caagctccct tacattatat cgaccagccc catggaaaga
     3301 ttatagctag actaatcaat gatataatac atactagaat acaaaatatt tttttattca
     3361 tactttttct cctatcttta ttttctacct acatagtacc tcttattaag ctcattttaa
     3421 aattacgtta acttttttca cgaaaaggag aaaattatgc gttattatta tggatagcgc
     3481 tttcaaattt ttaaactcct atcccgtcct tttatctata taataagcat aagcgaaaat
     3541 ataataactg tcaagtatct gaagtgaatt ttataaaaaa attacaagcc aaatttgtaa
     3601 agtttacatt aagccgctag ggcaatcgtc tatcagaatg tccgtttatt tgtcaataat
     3661 ccgagaaaat cttgcaacgc ttagaagtct ataaaaacta tcaacattta tatgacttgc
     3721 gaatagcaat cctgctcaac ctttccacac tctatctata caatcaagat aaaaacatgt
     3781 gtaagcaaat ctgctacact ttactagagg acgccaagaa taagaaaagc tacgataggc
     3841 tggctatctg ctatgtccgt attgggattt gtacagacga ttctaaactt atccaaaaag
     3901 gtttctcact cctagagctg accgaggaaa cttctatgct gtctcatctc aaaaaagaag
     3961 tagagaccca ttatcaacca aagaaattat aaaaaagtcg agggatttcc tcgactcttt
     4021 acatattatt tgttcgttag ttcttaatac cagccattgt taaaccagaa gtttttagct
     4081 ctgccaagcc acatagtgtg cttactacta tgtgtccatg tcaccatgaa tcgccgaacg
     4141 atttaacgag aaagtatgac ttttacgttt atcccaactc aattatgaca tttttttcaa
     4201 aagtcaatat atctcacttt ttcaacgaca agaaagaggc tgccaatcga ccaacctctt
     4261 attctgaacc catcactcca tcacttttta gcttcattcg ctttcttagc gactgcaatc
     4321 tggtattcga cttggtcaaa tcctgtgcct cccaaggaat ttcgtctttg aacagcagtt
     4381 ttaggttgca agtagacata gatatcctcg gtaatgagag aatgataggt ttgtaattcc
     4441 tccaaagtcc aatcttgaag atttttagca gacttgatag agtctagcac taatcttccc
     4501 acaacctcat gaacttctct aaatggcaag cctttccctg ccaaataatc tgccaactca
     4561 gtcgcatttg aaaagtcctt ctctgtagac tcttgcattt tttccttgtt tacctgcaag
     4621 ctggataaca tacctgccaa tacatcgaga gaatttaaaa tcgtttcgac cgtgtcaaac
     4681 attccttcct tatcctcttg caaatcctta ttataagcta agggcaagga cttcatgact
     4741 gtcaacagtc caaacagatt cccataaact ctaccagtct ttcctcgaat caactcagcc
     4801 atatctggat ttttcttttg gggcataata gaggaacctg ttgtaaacgt atctgacaag
     4861 gtaatgaatt ggtactcaaa actacaccaa ttgatcattt cttcgcaaaa acggctcatg
     4921 tgcatcatga gtatgctggc atttgacaga aattctaaga taaaatcgcg gtcactaaca
     4981 gcatccaaag aatttgtata aggtttctta aactccagca aatcgctaga caattggcga
     5041 tcaatgggga aagtcgttcc tgccaaagct gccgcaccta gagggcatag gtctgtatgc
     5101 ttctggttaa attcaaaacg ttcactgtct ctctgaaaca tattgtagta agccatcagg
     5161 tgatgggcaa aactaatagg ctgggcatgt tgcagatggg tatagcccgg cataatagtc
     5221 tccacatgat tttccgccaa gtctaataaa acacctttga gatgaaccag tttatctaag
     5281 acatggccta gttgttcctt gagatacaag tgcatatctg tcgcaacttg gtcatttcga
     5341 gaacgagctg tatgtaactt ccctgcaagg ggaccaattt tttctgtcaa caacacttcc
     5401 atattcatat gaatatcttc gtttgcgata tcaaagtcaa gttggcctgc ctctagctct
     5461 tctaaaagct ctttcaagcc tgcttggatc ttttctgact cctccaaact caaaatgcct
     5521 gtctgaccca acatctgaac gtgagctaaa gaaccaatca aatcaaattt agctaatttc
     5581 tggtcaaaag atatactcgc accaaagcgc tctacccagt cttcgacagt accttcaaag
     5641 cgaccacccc ataattttgt attcttagcc atatcacatc cacctctcta tccaatcgtc
     5701 ctatttggcg cttttttgaa cctcagaatg aaccttggtt ggaagtcccc acaacttaat
     5761 aaagccaaca gctgcatctt ggtcaaaggt atctgcacta gtatacgtcg ccaaattttc
     5821 atcataaagt gaatttggtg atttccgagc cacgacctga gcgcttccct tatagagttt
     5881 gacttttgca gtcccattga caactttttg agtctcttta atataagcaa tcaaggcttg
     5941 cgtagccgga ctaaaccaca aagcattata aatgagattt gataattcat tttctatgat
     6001 tggtttaaaa tgagccactt ctctcacaag cgtcaaatcc tcaatttcct tatgagctgt
     6061 cagcaaggtc actgcccctg ggcattcata gatttctctt gatttaatcc caactaagcg
     6121 attttccacg tggtcaatcc gtccaacccc atgtttccca gctatttcat tgagtttttg
     6181 aatcaaatct gccaatttta acacttctcc attgagggaa acagggacac cttcactaaa
     6241 ctcaatatca atgtattctg gcatatctgg agccgcctct ggagaagatg tgatgccaaa
     6301 ggcttcttct ggagcctgat tccatggatt ttccaaaata ccacattcat tggcacgtcc
     6361 ccaaagattt tggtcgacag agtaaggatt gtcaaggtca gcaggaacag gcaccccatt
     6421 ttccttggca taatgaattt cttcctccct agaccatttc cattcacgaa ctggcgcaat
     6481 cacttttaaa ttgggatcca aggctgcaat cgatacttca aaacgtactt ggtcattccc
     6541 cttacctgta caaccatggg caattgtagt cgctcctgtc tgatgcgcta tttcaaccaa
     6601 ttttttagaa ataagagggc ggctcaaggc agataccaag gggtactttt gttcataata
     6661 ggcatgtgac tgaagagcca ctagcacata atctgtagca aattcgtcct taacatcaat
     6721 aacataagat tcgactgccc caaccttgag agccttatca tggatgaagt ctaagtcttt
     6781 cccttcaccc acatccatac aaactgcaac aacatcatag tctttcttta accaggtaat
     6841 agcaactgat gtgtctaaac cgccagaata ggccaaaatt actttttctt tactcatgtt
     6901 cttttccttc tttctatttt tcaatggacg ctttaaaggc atcctcaatg agtttgtcta
     6961 attctccaga cttcttcaac ttttgaatgg ttttatcgac tgcctctttc aattccttgc
     7021 tatctttttt catggctacc gcgtaggaat catcttgctc tttttcaaaa ttgaggtctg
     7081 cgattgctaa atcaggatta ttttccacaa atcccttggc aacaggttct tcaaagataa
     7141 cggcatccac ttgtcctgat tttaaatctg tgattaaatt cccattttta ggcagagata
     7201 cgagggaaga attttgtagc aagtctttcg ccatcgtctc ttgaatcgaa ccattctgtg
     7261 ctccgacctt tttctgcgct aagtcgttga cagactgata agtggccaag tcagattttt
     7321 tgacaatgag tttatttttt gcagtatagt agggagttga aaaatcgaac accttgctcc
     7381 gttcatctgt cttagaaaca ccagatatgg caagatcggc ttttcctgat tgaacactag
     7441 ccagtacatt gtcaaaactc atgggagata gttccaattc gacacctagt tctgttgcga
     7501 tagctttggc taattcgata tctgaaccca caatctgatt tttcccatct accacttttt
     7561 gatattcaaa tggagcaaaa tctggattga gagctacaac caattttcct ttggacttga
     7621 tggcttcaat tccagccgat tgattgttgc tacaagcaaa tagtaggggg agcatcacta
     7681 aaccaaacat cgtcatcaac accttcttca tcttattcat aacaaagcct cctttatgtt
     7741 tattcttttt ggttgtataa ataatactcc tatactcatc ctttgtcaag tctaaattga
     7801 aaaaattttc aatttgaaac aaaaaaacct agaaatacta cataaaaatg tcatttctag
     7861 gcgtatttat gctatttctc tctggaaaat atgagtattc agtcagtcaa aaggagctga
     7921 acgaactcat ttcccctcgc ccaattcaat gatccgatga cattgttggg ctacataagc
     7981 atcgtgggtc acaataatga ctgttttccc ctctcgattc atctctaaga gaaacttcaa
     8041 gaccaaatct ctattttcag ggtccagaga acctgttggt tcatcggcta aaatcagctg
     8101 gctgggtttt aagatggctc tagcaactgc aattcgttgt tgctccccac cagataactc
     8161 ggaaaccttt tggtgcaaag tagctgacaa acctaccctc tctaaaatct cttccacctt
     8221 tttgagcttg tctttcttag acaatttcac atatttcagc gccagcataa gattgtactc
     8281 gaccgtttca tcatcaatca gggcaaaatt ttgaaacaga taagagatat gttcacggat
     8341 tattgtttgc gacttagcag aattaactgc tagatttgtc tgaccaaaaa tctcataccg
     8401 tccgctataa tcaccatcta tcaaacctaa taaatttaac aaggtcgact taccactacc
     8461 actcttgcca acaatggcta ccaaatcccc ctgatcaatc ctgagagata agttatccaa
     8521 aatcactttt cctccaatgg ttttggtaat attttccaac tcaatcataa gatgccccct
     8581 ttcaataact ctactagact tcttttctcc atcctagaag ccaagcctag cacaaatagt
     8641 atatccaaac atgtaaaacc tgcaaaaagt aggagtggca agagcgcatg ggcaaagaaa
     8701 atcaagacta gaagaggcag actatagccc agcaagagca gaacgaggag agggcggtag
     8761 cgatcgacca gtttccaccc cataaacttc ttggtaataa tatccctgcg cttcaataag
     8821 aaagttatta ctagtaagaa gtaggaaatc atcatgctaa ggagaccaaa caaagcaaag
     8881 agtaggttaa aattccgaac agcatctcga taagaatcca ctttctcttg ttgaatggct
     8941 tgaatagatg aaaattttaa ataatttcca tctgacaatt tctcaactaa ctctgtaatc
     9001 tctttttgat gttgaaccgt attttcaatt ttaatcggat tatttaagcc agttgttgac
     9061 agggaggctt tctcatccca catcatatca gaatcattga ccaagctaat aattggattg
     9121 gagagatttt cctttcgctt atcactatat gggaaaaatg accaatctcc ttcataatag
     9181 gcaatctcga catccatctc ctctatcgtt cgtttttgct gctcttcata cttcatcgaa
     9241 tgaaaggcaa ttaacttccc caagagctga tttttatctt cttcaccttt cgtacttgct
     9301 ggcatcaaaa taactttttt aataccggta tctggtagct tgaatccctt gctctttaga
     9361 aaatggcgat tggcatagta aacatccacc gtatctgtta actgatattg ctgaatctgt
     9421 tctgattgga caaaattttt tacaggaaga ctgctactct gcacatagcc cgcctgcgtt
     9481 ttttctacca aatcctgata aaatcgatag aaataatcca atgccttccc tgagcctgcc
     9541 aactgctctt gccacaagtt atcattgagt tggaaagttt ctaaggtcag ataatttcct
     9601 tggctgatcc actgtttctg gtaatccaac tctttgtttt cttgctccaa actttttcct
     9661 accccaacta gcaagactgt cagtaaaatg gtagttccaa ttttcatcaa ataattaaag
     9721 agtagaccaa atttgaaaga tgaaaaacct ttcagcagag agctgattgt cattttttgg
     9781 attaagaggt aagtcaacca actgataaag agataaagct gcaacagcaa aaaatgagac
     9841 aaccacagca taggaaacaa atcttttggc ttataatcaa gcaagaaaaa cacgcctaga
     9901 ttgatcacaa gagccccacc taggaggagg taaaggttgc cttttacaac atcagctaaa
     9961 acagccctat cttgaaaacc aagtaatttt tgtaccccaa ctcttttcat ctccatcatc
    10021 ggttgataca ctgtcactaa cacaagaagc aaaatagcca agacaaaaac aatggcagat
    10081 aaaagcaaat ctcgatttat gacttccact gcacttttgt aggtcggctc tagcaaggta
    10141 gcctggtcta tcttgaaaaa atcgctccat ttctgtacaa tcctatcctt gtccatctct
    10201 tgtgtagaag ttatcgtata gcgaccattt aaactacgag atgtatcctt gatataggtt
    10261 tgaaaagtca taagctgaat aggtttggct tttagaaagg tcggaatcgt accaagttta
    10321 ttggaaattt ctttattact atagactcct tcaccatctg tggtaaaatc aagagaagaa
    10381 atcccaaact cttggtaggg gaaggtatct ttatcaaaaa caccagactt gaccacctca
    10441 tcaccactgt ctgttttgat gatggagact ttatactcct ttgatacatc ctcaaaaaat
    10501 cgaagaacag acgctgcagg ttcgttaata tctttcaaat acaaatccaa agaatctaca
    10561 gtctttccca tttcttgaat ccgaaccact tctcgtgtat agtttacatt aaaaacaaaa
    10621 aaagtggtac acagaagcag gagtaacata cagaaattac tgattttttt cataaaagtg
    10681 cctccactac agttttccct ctccaaatag gagagggaag aattttactc aaatccatag
    10741 aaatattcca ttcctgttgg cggaatcttg gtgagggaag ctctagccca tgcctcaggt
    10801 tttgcataat ccttagaggt tctaccccca tgtctaacag ttgctgtatg atatcgagta
    10861 gaatgtaagt aatcagaata tccaaaagtt cctgtccaac ctactccata gttccattga
    10921 ccaccctcaa cccatactgc taaagcattt gtagtagcaa gtataccaca taccattaaa
    10981 gatgcaacac caattttaac taattttctc atgatttatt tctcctatta tcgagagctg
    11041 ttccgtaaaa acagctatag taatttatca acaagtatcg tagtccattg gactcacctt
    11101 ccttctatct catttcattt tttaacaacg aacttactct taaccgggag aatggtgcgc
    11161 ttctgtatca ggtccttgaa caaccagagt agtattaagc acactctaac tattactcaa
    11221 gaatcagtcc aataaacaat atggatagcg ctttcaaatt tttaaactcc catcccatcc
    11281 ttttatctat ataataagtg aaaatataat aactgtcaag taatcgaagt gaattttata
    11341 aaaaaaatta caagccaaat ttgcaaagtt tacaataagc cgctagggca atcgtctatc
    11401 agaatgtccg tttatttgtc aataatccga gaaaatcttg caacgcttag aagtctataa
    11461 aaactatcaa catttatatg acttgcgaat agcaatcctg ctcaaccttt ccacactcta
    11521 tctatacaat caagataaaa acatgtgtaa gcaaatctgc tacactttac tggaggacgc
    11581 caagaataag aaaagctacg ataggctggc tatctgctat gtccctattg ggatttgtac
    11641 agacgattct aaacttatcc aaaaagggtt ctcccttctg gagctaaccg aggaaacttc
    11701 tatgctgtct catctcaaaa aagaagtaga gatctattac caagcgaagg aaagataaaa
    11761 aagccgaggg atttcctcga ctctttacat attatttgtt cgttagttct taataccagc
    11821 cattgttaag ccagaagttt ttagcagcag tccatgaacc gtaacgtcct gcaacgtagg
    11881 catctgctac acgttcttgg ttttcagctg agtagtcacc gttcaggtat gaatctgtta
    11941 attggtaacg tccgatataa cgtccatttg tagctgtata gctaccacct gattcttttt
    12001 gagcgatcca ttctttggct tctgcttcag atccgcttac agttgaaaca actgtttcac
    12061 ttactactgg agtttctgct actggagctg aaacagtttc atcttgagcg gctggtgccg
    12121 cataagtagc tggcgctggt gttgcaacag gcgctacagg gccatcgata accaactctt
    12181 gatcaacata aatcaaatga atgttatcaa tgtggttgtt ttctgccaat ttttcaactg
    12241 ttgtgttgtg agtttcagcg atttctgaaa gtgtatcacc ttctttaaca gtgtaagttg
    12301 atgattcttg agcagataca aatgatggag caaatactgc aaacaaggca gctactcctg
    12361 caagagttgc tttaatcttt ttagttattg atttcatatt cgaaaattct ccttctttct
    12421 atagttctat catacccttt aaatattacc gtttcttgac acttttatgt agaaatatta
    12481 caaaattatt ttttatttcc ctaaataagg tgttttttgt cataaaagat actattttta
    12541 tgctatttga ggtattagaa aggttttcat ccacaattaa agccaagccc ctcattcttt
    12601 gatataatag agataagaat ttttataagg ggaaactgat gaaatcactt cgttttcaat
    12661 ctgtctttga tatcatcgga ccagttatga ttggcccatc tagtagccat accgctggtg
    12721 ctgttcgtat tgggaagatt gtctcttcca tttttgatga tactccgaca gaagttgaat
    12781 tccaactttt taactcattt gccaagacct atcgtggtca cggaacagac ctagcccttg
    12841 ttgcaggtat tttgggaatg aatacagatg atcctgaaat tccaaatagt ctggaaattg
    12901 cccacaagcg tggtatcaag attgtctgga ccattcagaa agacagcaat gcccctcacc
    12961 ctaacaccac taaaattact gttaaaaatg cccacaagac catcagcgtg actggtattt
    13021 ctatcggtgg aggaaatatt caggtaaccg aactcaatgg ttttgccgtc tctctcaata
    13081 tgaatacacc gactatcatc atcgttcatc aagatattcc aggtatgatt gcccttgtta
    13141 cagaggcgct ttcccgctat ggtatcaata tcgcccagat gaatgtcact cgtgaaaaag
    13201 ctggtgaaaa agccattatg attatcgaag ttgacagtcg caactgtgat gaggctatcg
    13261 aagaaattcg aaaaatccct catctccaca atgtcaattt ctttaaatag gaggaagcat
    13321 gttttattct atcaaagaat tggtcgagca agcagatctg gactttcaag gaaatgtcgc
    13381 agaactcatg attacaacag agtttgaatt gaccggtcgc gaacgtgaag aagtcttcct
    13441 tctcatggaa cgcaatctgg aagttatgaa agcctctgtc caacttggcc tcaatgaaaa
    13501 taaatctcgt agtggcctga caggtggaga tgctgccaaa ttggatcact acatcaaaaa
    13561 cgaaaaaact ttatcagatt acacgattct ctctgctgcc cgaaatgcta tcgcagtcaa
    13621 tgaacacaat gctaaaatgg gcttggtctg cgctactcct accgcaggaa gtgccggttg
    13681 tctcccttcc gttctcactg ctgctattga aaaattagac ctcagccacg agcaacaatt
    13741 ggatttcctc tttgctgctg gtgcctttgg actagtcatc gcaaacaatg cctccatctc
    13801 aggtgctgag ggtgggtgtc aagctgaagt tggttcagcc tctgctatga gtgctgccgc
    13861 cttgactctg gctgcaggtg gaacacctta tcaggccagt caagctattg cctttgtcat
    13921 taaaaatatg ctaggcctca tctgtgaccc tgttgcaggt ttggtcgaag ttccctgtgt
    13981 caaacgtaat gccatgggag ctagctttgc tttcatcgca gcagacatgg ccttggcagg
    14041 tatcgaatct aaaatccctg tggatgaagt gatcgatgcc atgtaccaag taggagcaag
    14101 catgccaact gcctttcgtg aaacagctga aggtggactc gctaccaccc ctactggtcg
    14161 tcgcctccaa aaagagattt tcggagaata agcttatcaa ataggagaaa ccatgacctc
    14221 tatcacagcg atttttttcg atttggatgg aaccctcgtt gatagttcta tcgggattca
    14281 caatgccttt acctatacct ttaaagagct gggggtgcct agccctgatg ccaaaactat
    14341 tcgtggtttt atgggaccac ctctcgaaag tagttttgcg acctgcctgt ccaaagacca
    14401 aatttctgaa gccatgcaga tatatcgttc ttactataag gcaaaaggca tctatgaagc
    14461 tcaactcttt cctcagatta tagacttgct tgaggagtta tcgagcagtt atccactcta
    14521 catcaccacg acaaagaata catctactgc tcaagacatg gccaaaaact tggaaatcca
    14581 tcatttcttt gatggtattt atggttctag ccctgaagca ccccataagg cagatgtcat
    14641 tcaccaagcc ttacagacac atcaactagc accagaacaa gccatcatca tcggagatac
    14701 caagtttgat atgctgggag ctcgagaaac aggtattcag aaattggccg tcacttgggg
    14761 atttggagag caagcagatc tactaaacta tcaacctgat tatatcgctc acaaaccctt
    14821 agaagttttg gcatattttc aatagcatag actgggtaac aattccattt cagaagaaaa
    14881 tgaagtaata ctcaatgaaa atcaaagagc aaactaggaa actagctgcg ggctgctcta
    14941 aacactgttt taaggttgtg gatagaactg acgaagtcag taaccatata cggcaaggcg
    15001 acgttgacgt ggtttgaaga gattttcgaa gagtataagt ctctacataa taaaacgcat
    15061 attaccaagg ttgtgtaact tgatactatg cgtttttctt ttttattcaa tgtgggttgt
    15121 ttgattagca aaggcgataa tagcttgctt caactcatct ccactgagag tgcggaactc
    15181 tccaatcttt tgattgatgg attctaaagg catgacatta accttaccaa cgaaaatctt
    15241 atccataact tgattatcaa caagttcggt tgataccaag agttcttcgt agagtttttc
    15301 acctgggcgg attccaactt caacgattgg aatttcactt tcagtgtggc cacttagaag
    15361 caccatcttc ttggccaagt cataaatctt gactggtttg cccatatcaa ggataaagac
    15421 ttccccatct ttggcataag caccagcatg gataaccaga cggctagctt ctggaatggt
    15481 cataaagtaa cgggtcatgc ggaagtctgt caccgttaca ggcccacctt cagcaatctg
    15541 acgttcaaag actggaatga cactaccacg gctaccaaga acattcccaa aacgaactgc
    15601 acagtaggtt gattggctac gttggttaaa gccagtgaca atcaactccg ccacgcgctt
    15661 ggttgctccc ataacatttg gtggattaac tgccttatct gtcgaaatca taaccatctt
    15721 agacacttta gcttcatcaa cagccttagc aacattgtaa gttccacgga tattgttttt
    15781 gaaggcttct tttggattgc gctccatcat aggaacatgc ttgtgggctg ccgcatgata
    15841 aacaatagca ggtttgtact gctcaaagac ttgcaacaaa cgatcatagt cttgaatgtc
    15901 cgcaatcaca ggtacataat caatcccttg gaacttacga atcaattcat gataaacaag
    15961 gtagattgag ttttccccat gaccgagcaa gacaatgcgt tcaggattga agcgactaac
    16021 ttgacgacag atttcagaac cgattgaacc tccagctcct gtgactaaga tggtcttacc
    16081 tgtcagttct gcacccagac gcgattcgtc aagacggatt tcctgacgac ccaaaaggtc
    16141 cgtaatatca attttttgga agccagtacc tgcttggtga aggccctgaa caacagtttc
    16201 aaccttaggc atcttgtaac atttgacacc cagcttatta cacatctgca agatacgctc
    16261 atattctgac ggatccagcg acggaatcgc aacgatgaca cgctcgattt gatggcgttt
    16321 ggctaattca ggcagattgt cataagagcc caaaacagga ataccaccaa gtttttgacc
    16381 ctttttctta gaatccttat ccaaaatacc gaccagttct aattcactgg ttggatgttg
    16441 gtaactatcc ataaagagag ccccaccatc accggcacca atcaagaagg tccgacggtg
    16501 ttctccatca ccactacctt ttttgcgtct ggagtagatt aactgccaag taatccgtgg
    16561 caataaaatc aagaaggtac tcaacaagat aaagagaatg atgaaacgga tggagaagag
    16621 tggcaagaag gcataacaga tactatatga caagacactg ctagcagtca caccaaaaaa
    16681 gattttcatg aaatccgtaa tcttgctgta acgactaatg ctcgcgttca atccccaaaa
    16741 accaatcatc aattgataga acaggaaggc caaactcgta tagataatgt agtcaacagg
    16801 tgctggatta atcagcccat aaaataaaat ataagataca attatggaaa ccaccatact
    16861 gaaaatatca aatattcccc agaaaacctg cttttgttgt ttatttaaaa tttccaccag
    16921 atcaatcaca taatctgtta gttttttatt catagaaatc tactcctcct taaaagagtt
    16981 ttactatatt gttattgtag catattttga tttatttggc ttattttatc caaataaatt
    17041 attgttccct tgtactcctt cttccattta aatcctctaa ttaaacctac aatcgtccca
    17101 aagccataag caaagtgaat ggaaaataaa agaaagggca tcacaattag aaatccattt
    17161 ttatgtttta ataaagtcag caaagtgagt agtgacaaaa gtagaaaata ggcacctaat
    17221 agtaaagtta tgaatacgaa tgtgatcggt aacaatgcta gactaaacac aagactcaaa
    17281 acaaataaac aaggaacata gtgaaataat gataaacact taaactgaac atgacttgtc
    17341 aagccaatcc acaaaccatt taaatacttt tgatgcagca ttttcttgaa tgttggtcga
    17401 atatactgat aagatagaat acttgggcta tagcggattt tataaccata ttctcgaatt
    17461 ctataatgaa tatcattatc ttcagttcgg ccaagttgct catttactaa accaaccttc
    17521 tggaaaacct ctcgtttata cattccatga aaaatagaag aaacatatct atcctcagaa
    17581 ctatttcgat aattggcaat gctactgcca aacatatttt cctcaacaag atgcaaggtc
    17641 tctgcccatt ttccttttcc ttcgacaatc gtcggtctag gccccccaca gacaaattca
    17701 ccttgttgaa taatagccac attgttcatt acaaaagtct cagtaacttt tgaatgagca
    17761 tcaattttta aaataaggtc ccctacagaa tgtttaactc ccaggttaaa accactagct
    17821 tgatttttct taggattgtt atacaatcta attgagttaa actctgtatc ttcctttata
    17881 aattgctgaa tgatagctgt ggtcccatct gtggacatag catttataaa tagaatttca
    17941 atattctctt taggataggt ttgatttttt aagtcttcaa ttagaccagg cagatatttt
    18001 tcttcattgt atgcactgat tacaatggat acgagaagac tttcaacatt ttgagtcact
    18061 actactctcc tgaatttttc cttccaccat tctatcataa ttttcaagac tttcccattt
    18121 ttatcttgaa agccagaaac cttacttgac attatagtga aaaagcctta aaataagctg
    18181 ttattaaaat cagctagaag aggtattata tgaaaaagca atcactcttt tttgttccag
    18241 gtattatcct gattggtgtt tccttgcgaa ctccttttac tgttttaccc attattttgg
    18301 gaaatatttc gcaaggtctg gaggtagaag ttagttcgct tggtgtcttg accagcctgc
    18361 ctctccttat gtttaccctc ttttcaccat tttctaccca actggctcag aaaatcggct
    18421 tggagcatct cttcacctac agcctcttct tcttgaccat cggctcactt attcgactaa
    18481 tcaatctgcc cctgctctat ctaggaacct tgatggttgg ggcaagtgtc gcagtcatca
    18541 atgtcctgct tcctagtctt atccaagcca atcaaccaaa gaaaattggt tttctgacca
    18601 ccttatatgt aacgtctatg gggattgcaa cggctctggc ttcctatcta gctgtgccca
    18661 ttacacaagc cagttcttgg aaaggactta tccttctcct cacgttactc tgtctagcaa
    18721 cttttttggt ctggctccca aatcaccgct ataatcatag actagctcca caaaccaaac
    18781 aaaaaagtca aataaaggtc atgcgtaata aacaggtttg ggcaattatt atcttttcag
    18841 gttttcaatc cttgatcttt tacaccgtca tgacctggtt acctaccatg tctatccatg
    18901 caggtctatc cagtcacgaa gctggcttgc tgacttctat cttatctctg attagcattc
    18961 ctttttcaat gaccatccca agcctgacaa ccagtttatc tactcgcaac cgtcagctca
    19021 tgctcactct ggtttcacta gctggtgtgg tcggcatttc catgctcttt ttcccaatca
    19081 ataatttcat ttactggctt gccatccatc tcctcatcgg aaccgcaacc agtgccctct
    19141 tcccttatct catggtcaac ttttcactca agacaagcgc ccctgaaaag acagcccaat
    19201 tgtccggcct atctcaaaca ggaggctata tcctagcagc ctttgggcca accctctttg
    19261 gttacagttt tgacctgttc cactcttggg taccatctgt agctgccctc ttgctcatcg
    19321 atatcctgat gactgtggcc ctctttacag tggacagagc ggataagatc ctttaaactt
    19381 ctagttttag ctagaagttt tttatatata aaaattttac acatttctct tgacagggct
    19441 ttcttttaga tgtacaatgt atgtgtagaa aaattatata taaaaatctt acacattaga
    19501 aaaggaggtt tcccatgtac tttccaacat cctctgcctt gattgaattt ctcatcttgg
    19561 ctgtactgga gcagggtgat tcttatggtt atgagattag ccaaaccatt aagctgatcg
    19621 ctaatatcaa agaatccaca ctctatccca ttctcaaaaa attggaaggc aatagctttc
    19681 tgacaaccta ttctagagag ttccaaggtc gcatgcgcaa atactactcc ttgacaaacg
    19741 gtggtataga gcagctcttg accctaaaag atgaatgggc actctataca gacaccatca
    19801 atggcatcat agaagggagt atccgccatg acaagaactg aatacctgac tcagctagaa
    19861 ctctatctca agaaactacc tgaagctgac cgtatcgaag ccatggacta tttcagagag
    19921 ctctttgacg atgctggagt cgaaggagaa gaagaactca tcgctagttt gggaactccc
    19981 aaagaagcgg cccacgaagt tctatccaat cttctcgata aaaaaatcaa tgaagcaccc
    20041 gctcaaaaaa ataaccgaca aattttacat atcgccttgt tagccctcct tgcagcacct
    20101 atcggcattc ctctgggaat tgccatcctc gtgaccctgt tcgcaattct tgtagccgct
    20161 ttgactgtca ttctggcttt ctttgcagtt tccatactgg gtatcatcgg cggattccta
    20221 tttttagttg aaagtttcac tgtcctcgcc caagccaaat cagcctttat cttgattttt
    20281 ggttctggtt tactggctat cggtgcttct tcgctagttt tacttggcat ttcctatgta
    20341 actcgcttct tcggtctact cattgttcgt ctggtacaat ttgttcttaa aaaaggaaag
    20401 agaggtaatc agcatgcgta aatggacaaa aggatttctc atctttggtg tggcgactac
    20461 cgttatcggc tttatcctgc tttttgtagg tatccaatct gacgggatta agagcctact
    20521 ttccatgtcc aaagaacctg tctatgatag ccgtacggaa aagctaacct ttggcaagga
    20581 agtcgaaaac ctagaaatta ctctccacca acacgcgctc accatcacag actctttcga
    20641 tgatcaaatc cacatttctt accatccatc tctttctgct aaccatgatc ttatcacaaa
    20701 tcaaaacgat agaactctga gtctcactga taagaaactg tctgaaactc cgtttctctc
    20761 ttctggaatt ggtgggattc ttcatatcgc aagtagctac tctagtcgtt ttgaagaagt
    20821 tattctccag ctaccaaaag ggagaactct aaaagggatc aacatctcag ccaatcgcgg
    20881 acaaaccacc atcataaatg ctagccttga aaatgcgacc ctcaatacaa acagctatat
    20941 cctccgaatt gaaggaagtc gtatcaaaaa cagtaaactc acaacgccca atatcgttaa
    21001 tatctttgat acagttctta cagatagtca gctagagtca acagagaatc acttccacgc
    21061 tgaaaatatc caagtccatg gcaaggttga actgactgcc aaagattatc tcagaatcat
    21121 cctagaccag aaagaaagcc aacgaattaa ctgggacatc tcaagcaact atggttctat
    21181 cttccaattc acaagagaaa agcctgaatc aagaggtacg gaattaagca acccttacaa
    21241 aactgaaaaa accgatgtca aggatcaact cattgcgaga tctgatgata atattgatct
    21301 aatatccaca ccaagcagac gttgacaaaa acgcttacat ttgctactat ggaaacatat
    21361 ttatctaact aaaaaggagg ttctaccatg aaacaagaat ggtttgaaag taatgatttt
    21421 gtaaaaacaa caagcaagaa caagcctgaa gagcgagctc aagaggttgc agacaaggct
    21481 gaagaaacga tagccaatct cgatacacca attggaaaaa atactcaagt agaggaggaa
    21541 gtctctcaag ctgaagtcga actggaaagc caacaagaag agaaaattga agctcctgaa
    21601 gacagtgaag cgagaacagg aatagaagaa aagaaggcat ctaattctac tgaagaagag
    21661 ccagaccttt ctaaagaaac agaaaaagtc actatagctg aagagagcca agaagctctt
    21721 cctcagcaaa aagcaaccac gaaagagcca cttcttatca gtaaatcttt agaaagtcct
    21781 tatatccccg accaagctcc aaaatctagg gataaatgga aagagcaagt gcttgatttt
    21841 tggtcttggc tagtggaagc gatcaaatct cctacaagta agttggaaac aagtatcaca
    21901 cacagttaca cagcctttct cttgctcatt ctgttttctg catcttcctt tttctttagt
    21961 atctatcaca tcaaacatgc ttactatgga catatagcaa gcattaacag tcgcttccct
    22021 gagcagctag ctcctttaac tcttttttct atcatctcta ccctagtagc gacaacactc
    22081 ttcttctttt cattcctctt gggtagtttc gttgtgagac gatttatcca ccaggaaaag
    22141 gactggacgc tagacaaggt tctccaacaa tatagtcaac tcttggcaat tccaatcttc
    22201 ctcactgcta ttgctagttt ctttgctttc tttgatagcc tacgatttac agctctcttg
    22261 tgtgtgatta gcattggaat cattctgctt gccagtctcc atatcattac aagaccaagt
    22321 caagcaagtg aaaccgactc cttctatcaa ttattcttgt ctgtccttgt gaacggagtt
    22381 attatcctcc tcttctttgt agctgaagtg gcactgattg gagattatct tcgtatcttg
    22441 gcctttcttt aaaattcaat cctgtcatcc ttggcaggat ttttctattt caaaaaagca
    22501 agtcgattga cctgcttctg ctttactttt cttgtgctaa tgttttaaaa tcttgtccta
    22561 ggatgggttg tacttctaat tgattggcgt ctagttggtg gtaaaatgct gatggtagtg
    22621 actctaggaa ttttgcatag tccaagcggg cgatggcttc atagtcttct ggtttagagc
    22681 catctcctgt gatttgaacc aagtcgatct cccactggac ttccttatcc accaattgct
    22741 caatataggc tgcaggaaca aacggttctc tcggtaaaac tgtcttgact ccttgagcta
    22801 gatggtaaac gccatgcact tttccttctc catcctgata gaaggaaact ctcgcaaagt
    22861 aggcatctgt ctcttgaacc gcacgcacac gcgcttcaaa ctgagccaag ccatctgcct
    22921 ctaaaaagct tttcaagttc tcacgactaa agaaaatagg attaaaaatt ccttggcaaa
    22981 tcgtaaaacg agctacaggg tctgctagat aggcttgaat acttgcttgg aaataagctt
    23041 caaaatcaaa accatctagc ccttcaatat cagtccctgt ataagcaagc aaagcatcta
    23101 aaaatgactt gataatctgc cagtctgtct ttgttagtag gtcaggaaga tcgacacggt
    23161 aagccttttg accatcagca taactgacct taaagagaaa ttgtgattgc cccactatcg
    23221 cacactcgat atattcgaga cgattaagag gctgacggag atagactaca tcatagctat
    23281 gtgactccaa accgtctagc aaggccaaga tcgacttggc attcaaaatt tcttgttctc
    23341 ctaaaatgct ctgtttattt ggaataaaaa atgttttcgc cataactgga ctcctttgaa
    23401 atcgtttaca tacagtatac cttatttttc tgaaagatac aaaaacaaac tttatactct
    23461 tcgaaaatct cttcaaaccg cgtcagcttc gccttgccgt agatatatgt aactgacttc
    23521 gtcagtctta tctacaacct caaagcagtg ctttgagcag cctgcggcta gcttcctagt
    23581 ttgctctttg attttcattg agtattagat ttttgagtac aaagcataga aaaacagccc
    23641 ctgaggactg tttgatctta tacagtagct gcttgatcca agctttcacc gatagcggct
    23701 aggcgctcga tcacttcagc ttgtgtcaat tcattttttg aaacatagcg gttacgtggg
    23761 tgaacacggc actcgtgtga gcatccacga aggtacttgt cttcattttc ttctgatgtc
    23821 aagatacgac ggttacagaa tggatttcca cagttgacat aacgttcaca tggtgttcca
    23881 tcaaaccagt ctttccctac gatagttggg ttgacatggt tgacatcaac ggcaatacgc
    23941 tcgtcaaaga cgtacatttt cccatcccaa agctcacctt gaacttctgg gtctttaccg
    24001 taagttgcga ttcctccgtg caattggcca acatctttgt aaccttcacg gaccatccag
    24061 cctgagaatt tctcacagcg aacgccacct gtacagtaaa ccacgacacg cttgtccatg
    24121 aatttttcct tgttatcacg gacccattgt ggtaactcac ggaagttgcg aatatctggg
    24181 cgaatagccc cacggaaatg tcctagatcg tactcataat cgttacgtgt gtcaaggaca
    24241 acggtatctt tatcaagaag cgcttctttg aactcttttg gagacaagta agcacctgtt
    24301 gtttcaagtg ggttgatgtc attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt
    24361 tctttcttgt agcgaacaaa catcttcttg aaggcttgtt cattttcttc gtcaatcttg
    24421 aaccagagat cttccatacc tgggaggctg tgaacgtagt ccatgtattt ttgagttgtt
    24481 tcatagtcac ctgaaactgt tccgttaatt ccctcgtcag cgactaggat acggccttta
    24541 aggccgattg atttacagaa agccaagtgg tctgcagcaa attgctctgc attttcaatt
    24601 ggagtataaa ggtagtaaag taagacacga atatcttttg ccataagatt tgttctcttt
    24661 tctattctta aattttctaa attttttatt tatccatact agtatacctg cttgagaaaa
    24721 cgaatgcaat ttatttgact ggaaattgta gaggattctc gaaatttcct gaatggttaa
    24781 aataaggaca agagaaaaca gggatatcta tatccttgtg ccaaaaaaac cactgccctc
    24841 cccagaccaa cctgaggaaa gcagtgattc ttattttagg agttaggaat gaatacacga
    24901 aatcaattta gctgattatt ttttgttttt caagaattca tcgtattgtt tttgcatttc
    24961 gttcaatact ttttcgtagg caccttcaga tttcaatttt tccatcaatt ctggaatcgc
    25021 tttatctggg tctacagtac cagtgttgat agctgtatca aattgttgca ttgtgttagc
    25081 aatagctgag atttcagatt tcacattgtc agtattaaag ataaatccaa gcgctggaga
    25141 ttctttagct tctgccaatt ctttcttaga attttcgatt tgttggtctg taacgttttc
    25201 gttgatgtaa aggatccagt tgttaccagt gttccatcca cccatgtgag tgtttccttt
    25261 gtagccatca agaacgcgaa cacgattttc tttaccttca attttttccc agttcttgcc
    25321 ttctggaccg taaacaagac cgttcaagag ttctgggttc gtattcaaga ggttcaacac
    25381 ttccattgat ttttctttgt tcttagagtt gtttgagatg acaaagttag caacttgtgt
    25441 tgtttggttt ttcttgatga agttagtaat tggtttgatt tggatatctt tgttggcaac
    25501 acgtgaaagc aagctgttac cgtagtcagc tggtcctact gtttcttcac gaacgaacca
    25561 agtatcttgt tgaaggtcaa atgaagtatc gcttgttgcg acatcttttg gaatgtagcc
    25621 agcttcatag aatttgtgaa gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg
    25681 gtttacaact ttagtagtat cgccttcaag atcaataacg aatggaagcc cgtttgctac
    25741 tgggtagtca aagttatcag atgggatgaa aactttacca atagcaaatg gtactacgtc
    25801 tggagctttt tctttaattt gtttcaagac tggctcaaga gtttcgtaag aagtaacacc
    25861 tgaaatatcg ataccatatt tggcaaggag agttccgttg aaggcaaagt tttgagatga
    25921 tgcaacgttg gctgcaactg gaacagcgta aattttaccg tttacagtat tacccttgat
    25981 gtaagctggg tcaagtgcct tgtaaaggtc tttaccttct tttttgtaca attctgtcaa
    26041 gtcagcataa gcaccttttt gagcatttac aatatagtta tctgcaaagg cgatatcata
    26101 gttttcacca gatgatgtga taactgacat tttcttacca tagtcacccc agccaaggta
    26161 ttggatatcc aatttggcac caactttttc ttcgatgatt ttgttggcat ttgctaacaa
    26221 ttcatccaag ttatctggtt tgtcaccgat ttggtacatt ttgataacag gtttgtcacc
    26281 tgaatcagca gcttttttgc tgttacctgt caaatttcca caagcagcaa gacctgcagc
    26341 caaagcgact acactagcag atgcaaaagc atattttttc cagtttttca tgataaaaac
    26401 tccttttttt atttttaaac ttataaacaa tgtaatgatc ttaacttcac gcaagggaag
    26461 tttggaaaca agtgctattc tttcacacca ccgatagtca aaccttttac aaagtagcgt
    26521 tggaaaaatg gatacaaaat cgcgattgga agggttgcaa ccacaaccat ggccatacga
    26581 cctgtttctt tcggtagagc aactcccagt tgaccagtca agccgaccgc tttggcaatg
    26641 tagtccatat tttgttggat ttgcatgagc aaatattgca atggatacaa gttgtcactc
    26701 ttgatgtaaa gaagggcgtt gaaccagtca ttccagaaac caagagctgt taagagcgtg
    26761 atggttgcga tacctggtag tgacaatggc aaacagattt ggaagaaaat ccgggcttca
    26821 ctggcaccat cgatacgagc cgattctaga atggcttctg gaatggtctt cttgaagaag
    26881 gaacgcatca agatgatgtt aaatggtgag agaagcattg gaacaatcaa ggcccaaaca
    26941 gtatccccaa gctgaagtac acgggtcacc atgatataac ctggtaccaa accagcgttg
    27001 aacaacatac tgagaaggac gaagatggta aaaaatctgc gatacttaaa ggttgtccgt
    27061 gaaatagcgt aggcataggt tgttgtgata aagacatttg tcaatgtccc aactacggtt
    27121 acaaagacag agatgaagag ggcttgtagg attttatcct taaactgtgc caaaaactca
    27181 aaaccgtcta agccaaattg ggatgggaag aagctatagc cgtattggag gaggcttttc
    27241 tcgtctgtca ctgaaataat gataacgaat acaaaaggta ggatacaaga gagggcaatc
    27301 aaacccgaaa tgatactgaa gaagatatct gctttcttac tgaaggagtg aatgccgaca
    27361 ttatcaattt tttctttttt aattttcttt tttgccatat tctcctcctt tctagaacaa
    27421 agctgagttt ggatcgactc gtcttgcaag caagtttgat aggataacca gaatcaaacc
    27481 aacaacggat tggtaaagac cggctgctgc agccataccg atatctgctg tctgagtcaa
    27541 accattaaag acatatacgt ccaaaacgtt ggttacattg taaagctgac cagcattgtg
    27601 tgggatttga tagaagagac cgaagtctgc gcggaagata tttccgactg caaggatggt
    27661 caatacagtt acaagcggag tcaactgagg aatggttacg ttgcgaatac gttgccactt
    27721 gctagctccg tccactgtcg ctgcttcgta gtaggttgga tcaattccca tgatcgtcgc
    27781 atagtacatg acactgctat atccaaagcc tttccaaata cctaggaaaa gtaggagata
    27841 gggccagatg cccaggtcag cgtaaaaatt gacttctttg agaccaagac tttccaatag
    27901 atgattgaac acccctttat caatatttag gaaggcatct gtaaagaaac tgatgataac
    27961 ccaagacaag aagtaaggga acaacataga agtttggaaa atcttcacca ttctcttaga
    28021 acggagctcg ctgaggataa tggcaatccc tacagataca actaaaccta gaaagataaa
    28081 gccaagactg tagaggacag tatttcgtgt gataataaag gcgtctcttg aactaaataa
    28141 gaatctgaaa ttatcgagtc cgacccattt actatttatg atactatcta tgaaaccatt
    28201 actggtcatg tggtagtctt tgaaggcaac cacgttccca aatactggaa tgtaaaagaa
    28261 tagaatcaac cagagtgccc ctggcaaaac catcaagaga aagatccagt tgtctctcaa
    28321 tgtttttgaa aactttttca taatttcctc cctttttatt ttgatatcca tctaaaaatt
    28381 cttttttaga cttttgataa cgattacatt attagtatac tcctatttgt aggttaggtt
    28441 aaactcctaa ttatagaaaa aactccacaa attatgtagc agatttaaaa ctttatcacc
    28501 actatcaaac aaatgtccta aatcaattgt ttattttatc tctattagcc cagtgatggc
    28561 gtcactctgt tataaacatc caacaacggg ggatactgaa aaatctccag actagggaac
    28621 tcagcgatag ttcctaatct ggagattttt aatatgttat taggcgtttg ctttcaactt
    28681 agcaataacc tctttaagat tatcaatcac ctctgcttca gtatgctcag agcctttttc
    28741 atctgccaag aacaaaactg ctttttgaag ttctttttga gagttttcaa ggacatcctt
    28801 atctactgtt tcaaggtttg agtctttaag aagtttactt aattccttgg ctaatttctt
    28861 gagtttgatt tgcagactca tcttctcctg ctgtttcttt gcccgctgtt tgtcctccat
    28921 ccttagttgc tgactggctt tccttaatgg actctaggga agcaatggca tctttgactg
    28981 tttgcaagat atcacgtaaa ccttgctctg tcaaactatc atctgcaaaa gctttcttag
    29041 cctctgccaa aaccagacgt gctgaatctg tggtaggatt cgatacacct gtcaatgatc
    29101 tcaaaagatt ttctaaggtt tgagtctgct tactaatact agactaaaat caaaaagtat
    29161 tatataacag tgatatgaaa tcaactaaag aagaaatcca aaccatcaaa acacttttaa
    29221 aagactctcg tacagctaaa tatcataaac gccttcaaat cgttctattt tgtctgatgg
    29281 gcaaatctta taaagagatt atagaacttt tatagtagtt tgaaataaga tgtgaacatc
    29341 tctatcagga aagtcaaatt aatttataga aatattttag cagccaaggt gtactgttat
    29401 agattcaata cactatactt ggtggtttag ctctcctgtt ttctctttta gctttaacca
    29461 gccataaatg gtattacgtg agatttggaa aacgtgtgat gcttctgtta tactacctgt
    29521 tcgctcacaa taagagagaa cttttttacg aaaatctatt gaatatgcca taaaaggatt
    29581 ataccacatt gtgtactatt tttggttcat tttactatat cactttggac tatatcggtc
    29641 tagttatgtc tcaacgatta tagctggata ctaagagaaa tcaaaaaagc actaagggag
    29701 aacgtcccaa agtgcttaat atcaaggcct caaagcctat cttattcaat aaaatattac
    29761 aacattttgt tgtagaattc aacgacaagt gcttcgttga tttctgggtt gatttcgtcg
    29821 cgttctggca agcgagtcaa tgaaccttcc aacttttcag cgtcgaatga tacgaatgct
    29881 ggacgtccaa gagtagcttc tactgcttca aggattgctg gaactttcaa tgatttttca
    29941 cgaactgaga tcacttgacc tggagttacg cggtatgatg ggatatcaac gcgtttcccg
    30001 tcaacaagga tgtgaccgtg gtttacgaat tgacgagctt gacgacgagt agtcgcgaga
    30061 ccaagacggt aaacaacgtt atccaaacga cgttccaaaa gaagcataaa gttgaaacct
    30121 aggattccgc ctttgatttt tgtagcttgt acgaacaagt tacggaattg tttttcacct
    30181 acaccgtaag tgaaacgaag tttttgtttt tcagccaatt gcaaaccgta ttctgacaat
    30241 ttagaacggt tgtttggtcc gtgttgtcct ggtacgtagt tacgacgtgc caattcttta
    30301 cctgtacctg taagtgaaag gccaaggcga cgagcttgtt tccaagatgg tcctgtataa
    30361 cgtgacatat gaatgtcctc ctgatataaa taatatttcg gtggaaatag tcacttagaa
    30421 agccctgatt cgtgcagatg cccttcgcct aaacagccaa ggttacttgt cataagacac
    30481 ctgttgacga gcttcatgct ttcctgctga tatttcacac aaaatccatt ttaccatgaa
    30541 tagctggatt tgtaaagggg ttttaggctt tattttcact accagagagg ttgagaacaa
    30601 gggtaaaggt acttcctaga ccgtactggc tgctgactgt gatttcccca cccaattgat
    30661 gggccaattc acgcgcaatc gcaagtccta atccatgacc acctgtcttc atgttacgcg
    30721 aagtttcgac acgataaagg cgtttgaaaa tattttccaa atcctctggg gcaatgccct
    30781 gcccttcatc ggtcacactg attgaaagct ggtccttctc cagcttagcc accacttcca
    30841 gcttggttcc tggagcagaa tatttaaaag cgttatcgac cagattcacc aagatacgag
    30901 aaagcttagc ataatctccc tcaatccggg cagactctgg gattacctgc aagtggacat
    30961 ctcttctctc ctgctcaatc aaaaactgaa attcactcat gcactcaatt aagagcttgt
    31021 ccagaaaaat actgtcttta ctggtagttt ccacctgatt tctagctgtg tttagggtca
    31081 aaaaattcaa ctcctcaacc agtttattga gcctctccgt ctggcgtcca atggttgcta
    31141 gataatgagc ttgctccgac tccttgataa tcccatccaa aatcccttct accgtcgctt
    31201 ggatcgaagt gataggggtc ttaatatcat gcgacaactg ggcaatcatc aagccctttt
    31261 ctcgttcgct ttcttccaag gaatcaaagc ttacctgcaa atcatgggac atctcattaa
    31321 aagtttgccc taattgctga aattctacag gaccttgaac ctccaaattt gaaggaaaat
    31381 ccttggccgc tacccgcttg gcatgctcct tgagtttgcc caacgacgta aagactggca
    31441 ataggagaaa gagactaatc ccagcaccga caaggctggc aacgatggtc atcccaagca
    31501 aaaagtaaat ctcgcctttc gcaatcagca ttttttgaac agcccaaaaa acaaccaaaa
    31561 tggttaagag ggttgaaata atatatccaa ccaaaatata actttttagt ttcatgtttg
    31621 tcctctcggt ttctctatct tatatcccaa cccccaaact gtcttaatag tgggcgtttg
    31681 gtcactacta tattttgcca gctcctgtcg aagagcatgg atatgcacat tcaaggtatt
    31741 ggtgtcatcc acgtagtctt ctttccagat cttttcatag aggtctgtct tggagaaaac
    31801 tcgctctgga ttgctagcta aaatccacag caattcaaat gatttaacag ttaaatccag
    31861 catttcttct cctatttgaa cttcatgact actatgattc atttttagat tgccaaggga
    31921 aatcagctct gtttcgcccc cacgatgaag gcggcgcaaa atattgtgga cacgcaaaac
    31981 cagctcacgt gggctaaaag gcttagcaat aaaatcatct gctcccaagc tcaggccgta
    32041 aatcttgtcc tgttcactgg tcttagcagt aataaatagg aaaggctgct ctggtgataa
    32101 gtattgaacc tcactgatta aatcataacc atccatccga ggcatcatga catctgtgat
    32161 aatcaaatca atcggttttt tcttgaacag ctctagcgct tccagtccat catgggctac
    32221 caagacctga taacctgcct gaattaagta tctctgatga atatctgtga tttctacctc
    32281 gtcgtcaacg agtaaaattg tctttcccat ctgtctctcc tttgataaaa acagtgctat
    32341 actgctttaa gtataacact atttttattg ttttacgatg attttaatct gctattgaaa
    32401 gaaagtcctg attgctgatt gagttgttaa actaatctta gtcagcccac tatccatcat
    32461 ttatttcctt agctgattag ttttcttctt ttttgttttt caaacctaga ccaccgagta
    32521 aacctgcaag cgcaagccca aggaaaccaa tacttgccat tgatgtttga gtctcaccag
    32581 tatttggtag catagcttta tcctctgaca tcatcgtatc agacatcttg ttagcagaag
    32641 cagccatgtt ttcacctgcc atcgtgttgg tagaacttgt catggtgtca gcaggcatgc
    32701 tatctgtagt acctgtagca tgattgtgat tcatcggagt cacgccagaa ccagagttag
    32761 aaggtgataa tgaaccattt gctgtgtctg atgtttcttt aacatttatc ttaatagtga
    32821 cttttttagt tgctacgatg ttgtccaaat ctggtttacc gtctttgtta ccatagacat
    32881 tgactgtagc gctgtaagtt tgagtaccat ttgctcggaa ctggtcaatg agcgcttgtt
    32941 tttctttgcc agctacattt ccgtccaagg ctaattgata gaagtattga cctttggtct
    33001 tcacgttttc acctagtgga gatagagctg ggtttttagc gtcgccgtta tctgaccatg
    33061 gtgccttgtc agatgccttg agcaagagac gagtcaacat accatcacct gcgaagagtt
    33121 cgtatggaat cacatggttg acacctgctg tgaatggacc ttcacccttg gccttttcta
    33181 ggtaggctgc tggaacatcg atactgtcct taacgttgtc tgcaacggct ttttgaactg
    33241 tttctttaga aattaaaccg tttatgttaa tagtgacttt tttagttgct acgatgttgt
    33301 ccaagtccgg tttaccgtct ttgttaccat agacattgac tgtagcgctg taagtttgag
    33361 taccgtttgc tcggaactgg tcaatgagcg cttgtttttc tttgccagct acatttccgt
    33421 ccaaggctac ttgatagaag tattgacctt tggtcttcac gttttcacct agtggagata
    33481 gggctgggtt tttagcgtcg ccgttatctg accatggtgc cttgtcagat gccttgagca
    33541 agagacgagt caacatgcca tcacctgcga agagttcgta tggaatcaca tggttgacac
    33601 ctgctgtgaa tggaccttca cccttggctt tttctaggta ggctgctgga acatcgatac
    33661 tgtctttaac gttgtctgca acggcttttt gaactgtttc tttagaaatt aaaccgttta
    33721 tgttaatagt gactttttta gttgctacga tgttgtccaa gtccggttta ccatctttgt
    33781 taccatagac attgactgta gcgctgtaag tttgagtacc atttgctcgg aactggtcaa
    33841 tgagcgcttg tttttctttg ccagctacat ttccgtccaa ggctacttga tagaagtatt
//
LOCUS       DAVMCG010000019        33152 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVMCG010000019 DAVMCG010000000
VERSION     DAVMCG010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.019"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(198..335)
                     /locus_tag="VYP66_001106"
                     /pseudo
     CDS             complement(198..335)
                     /locus_tag="VYP66_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(713..1402)
                     /gene="rplA"
                     /locus_tag="VYP66_001107"
     CDS             complement(713..1402)
                     /gene="rplA"
                     /locus_tag="VYP66_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1850667.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1610..2035)
                     /gene="rplK"
                     /locus_tag="VYP66_001108"
     CDS             complement(1610..2035)
                     /gene="rplK"
                     /locus_tag="VYP66_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1850668.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(2299..3015)
                     /locus_tag="VYP66_001109"
     CDS             complement(2299..3015)
                     /locus_tag="VYP66_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1850669.1"
                     /translation="MKKRYLVLTALLTLSLAACSQEKAKNEDGEAKTEQTAKTDGTVG
                     SKSQGTAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            complement(3018..3488)
                     /locus_tag="VYP66_001110"
     CDS             complement(3018..3488)
                     /locus_tag="VYP66_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1850670.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLVQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETCQAKSDEIKQLVKRLSSELDKLLEIKE"
     gene            complement(3490..4527)
                     /locus_tag="VYP66_001111"
     CDS             complement(3490..4527)
                     /locus_tag="VYP66_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1850671.1"
                     /translation="MNQTVKYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEEHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVSNEKETRALGIEVG
                     DFISFDPRTVVTEAGFIKSRHLDDKVSAAILLNLLLIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            complement(4625..5950)
                     /gene="brnQ"
                     /locus_tag="VYP66_001112"
     CDS             complement(4625..5950)
                     /gene="brnQ"
                     /locus_tag="VYP66_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1850672.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVMVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6121..6213)
                     /locus_tag="VYP66_001113"
     CDS             complement(6121..6213)
                     /locus_tag="VYP66_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1850673.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLVFEEL"
     gene            complement(6256..6408)
                     /locus_tag="VYP66_001114"
     CDS             complement(6256..6408)
                     /locus_tag="VYP66_001114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1850674.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGARNLPLSQ
                     LADSYD"
     gene            complement(6568..7146)
                     /locus_tag="VYP66_001115"
     CDS             complement(6568..7146)
                     /locus_tag="VYP66_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1850675.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7200..8600)
                     /gene="pepV"
                     /locus_tag="VYP66_001116"
     CDS             complement(7200..8600)
                     /gene="pepV"
                     /locus_tag="VYP66_001116"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1850676.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8613..9218)
                     /locus_tag="VYP66_001117"
     CDS             complement(8613..9218)
                     /locus_tag="VYP66_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1850677.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            9389..10189
                     /locus_tag="VYP66_001118"
     CDS             9389..10189
                     /locus_tag="VYP66_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1850678.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10371..11204)
                     /locus_tag="VYP66_001119"
     CDS             complement(10371..11204)
                     /locus_tag="VYP66_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1850679.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWDDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(11194..13041)
                     /gene="uvrC"
                     /locus_tag="VYP66_001120"
     CDS             complement(11194..13041)
                     /gene="uvrC"
                     /locus_tag="VYP66_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1850680.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(13081..13782)
                     /locus_tag="VYP66_001121"
     CDS             complement(13081..13782)
                     /locus_tag="VYP66_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1850681.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13861..15093)
                     /gene="murN"
                     /locus_tag="VYP66_001122"
     CDS             complement(13861..15093)
                     /gene="murN"
                     /locus_tag="VYP66_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1850682.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15098..16318)
                     /gene="murM"
                     /locus_tag="VYP66_001123"
     CDS             complement(15098..16318)
                     /gene="murM"
                     /locus_tag="VYP66_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1850683.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRVV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMIWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(16430..17209)
                     /locus_tag="VYP66_001124"
     CDS             complement(16430..17209)
                     /locus_tag="VYP66_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1850684.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17278..18939)
                     /locus_tag="VYP66_001125"
     CDS             complement(17278..18939)
                     /locus_tag="VYP66_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1850685.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFIPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19114..21336)
                     /gene="recJ"
                     /locus_tag="VYP66_001126"
     CDS             complement(19114..21336)
                     /gene="recJ"
                     /locus_tag="VYP66_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1850686.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIAFMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21613..22371
                     /locus_tag="VYP66_001127"
     CDS             21613..22371
                     /locus_tag="VYP66_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1850687.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLETVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22382..23176
                     /locus_tag="VYP66_001128"
     CDS             22382..23176
                     /locus_tag="VYP66_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1850688.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23189..23866
                     /locus_tag="VYP66_001129"
     CDS             23189..23866
                     /locus_tag="VYP66_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1850689.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23876..24535
                     /locus_tag="VYP66_001130"
     CDS             23876..24535
                     /locus_tag="VYP66_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1850690.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALVEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24793..25983
                     /locus_tag="VYP66_001131"
     CDS             24793..25983
                     /locus_tag="VYP66_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1850691.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTIKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26304..27185)
                     /locus_tag="VYP66_001132"
     CDS             complement(26304..27185)
                     /locus_tag="VYP66_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1850692.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27326..28654)
                     /gene="vncS"
                     /locus_tag="VYP66_001133"
     CDS             complement(27326..28654)
                     /gene="vncS"
                     /locus_tag="VYP66_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1850693.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMYLDAQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28651..29307)
                     /gene="vncR"
                     /locus_tag="VYP66_001134"
     CDS             complement(28651..29307)
                     /gene="vncR"
                     /locus_tag="VYP66_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1850694.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(29356..29439)
                     /gene="pep27"
                     /locus_tag="VYP66_001135"
     CDS             complement(29356..29439)
                     /gene="pep27"
                     /locus_tag="VYP66_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1850695.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(29619..30998)
                     /gene="vex3"
                     /locus_tag="VYP66_001136"
     CDS             complement(29619..30998)
                     /gene="vex3"
                     /locus_tag="VYP66_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1850696.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31050..31697)
                     /gene="vex2"
                     /locus_tag="VYP66_001137"
     CDS             complement(31050..31697)
                     /gene="vex2"
                     /locus_tag="VYP66_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1850697.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31710..32987)
                     /locus_tag="VYP66_001138"
     CDS             complement(31710..32987)
                     /locus_tag="VYP66_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850698.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9372 a         7604 c         6193 g         9983 t
ORIGIN      
        1 agtcagtaac catacgcacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga
       61 gtattagaaa gctcgatgga ctattccaga ttcattccac tagatttcga aatcgagtag
      121 gggataatct ctagcccctc tcacaccacc gtacgtgccg ttcggcatac ggcggttcaa
      181 ctaactgtta acgcatgtca ttcaaggtaa taatccaaac acgaaaccag tccacgtttt
      241 tcaaggactg gttttgatat agcacgttta agtaccgact tctgagctac taattgatag
      301 tggtcgcccc agccagatac cttatccgct atataggcct tattatcacg ttcctgttcg
      361 tagagccacg atttcgctat cccttcctct gacgattctt atttccagcg tcagacttaa
      421 aacggtctat ccccagaccg ttttaatccg ctacctcacg atagtcagac ttgggaatcg
      481 ctattgggtt caccggtagc aggtgcccac cgaggactta cacctcaaat atataataaa
      541 atgaaataag aataggacga atcgatcagg acagtcaaat caatttctaa caatgtttta
      601 gaagtagatg tgtactattc tagtttcaat ctactataca acatgcccgt cgtacatcaa
      661 aaaaagttga gacatagcgt cttcaacttt tttacattac tttaactact gattaaagtg
      721 agtttacgtc aactttgata ccaacacctt gagtagttgt gatagtcaag tttgttacgt
      781 aagttccttt agctgtagct ggttttgctt tttggattgt ttcgttgaaa gctttaaagt
      841 tttcaaccaa tttttcagct tcaaatgata ctttaccgat gattgcttga acgttacctg
      901 cacggtcagc acggtaagtg attttaccac ctttagactc ttcaactgct ttagcaacat
      961 ccattgttac agtaccagtt ttagggtttg gcatcaagtt acgtggtcca aggacacgtc
     1021 caagacgtcc aacaagagcc atcatatcag gtgtagcgat aactacgtcg aagtccaacc
     1081 aaccgtcgtt gattttagca acaaggtcat cttcaccaac aaagtctgca ccagcagctt
     1141 ttgcttcttc agcttttgca ccacgtgcga aaacaagaac acgtgaagtt ttaccagtac
     1201 cgtttggcaa taccattgct ccacggattt gttggtcagc ttttttaacg tcgatgttca
     1261 agttgtaagc aacttctaca gttgcgtcaa attttgcaaa gttagtttct tttgcaagtg
     1321 ctacagcttc ttctacactg tatgcttttg tgctgtcgat tttctcaaga gcagcacgaa
     1381 gttgtttgct ttttttagcc attttctatt ctccttgtaa gtggttcaat cgattttcat
     1441 ctcccacgtc acttctcgaa atgatgaagt cttgcgggtt ttcagtctac tatttttctc
     1501 ttcctacggc cttaagctcc cttgctgtac ccaagtacaa ggctcagtca cttgcctagt
     1561 atgaaaagca actaatagac tgctgtgaga ttttctactg tgttattgat tagtcaacaa
     1621 cagtgaatcc catagaacga gcagtacctt cgatcatacg cattgcagac tctacgtttg
     1681 ctgcgttcaa atctggcatc ttagtttctg caatttcttg tacttgtgca cgagtaactg
     1741 tagcaacttt agttttatta ggtgtacctg atcctttttc aacacctgca gcttttttca
     1801 aaagaacagc agctggtggt gttttcgtaa cgaaagtaaa tgatttatct tcgtaaactg
     1861 agataacaac tggaatgatc ataccagctt ggtcagctgt acgagcgttg aactcttttg
     1921 tgaatcccat gatgttgata ccagcttgac caagagcagg tccaaccggt ggagctggtg
     1981 tagctttacc agcagggatt tgcaatttta caagtttttc gactttttta gccatttcta
     2041 aatcctcctt tgtggttttg gcggtaatgt aagattttta cctcccacaa gtatgttttt
     2101 cacataccca tccattatac actatttatc tggaattgca agagaaaagt ttatttttta
     2161 tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgctc aaaacactgt
     2221 tttgaggttg tgaatagaac cgacgcagtc agtaggtaag gcgacgctga cgtggtctga
     2281 agagattttc gaagagtatt aatcgacgta gtctccgcct tcaaagccat agtattcttc
     2341 caaactgaga ccactctcag caatttcttt tgcttctttt ccgacataac gcaagtgcca
     2401 ttcctcagcc atatagcctg tttccttttc cttgcctttg agataacgga caacaaagcc
     2461 ataatcagca gcatggtcca agagccattg ggctgctttt tcttctgtca ccaaatcacc
     2521 atcagtccca atcacatcaa aggccaagcc tgtttggtgt tcgctatagc caggtcgagc
     2581 agaataacgg tcagcagctt ctttcccatc ttgattgaca taatcttggt agagcttggt
     2641 ctgagtttca taacttctaa agccactgta atggtcactg attgggaaac ctgcctcttg
     2701 catcgctttg atgagtttaa ccaactcagc cttggctgtt ggattttccc ctggattata
     2761 gtctttagac aatggatagt gtttgttggc tacgatgatt tcatcgtatt tcccttgaat
     2821 gctgtaatag tctcctttgt taaccacttc tgctttcttc tgggcagttc cttgagactt
     2881 acttccgact gttccatcag ttttggctgt ctgttctgtc ttagcttctc cgtcttcatt
     2941 ttttgctttt tcttgtgaac aagctgctag actcaaggtt agcaaggctg tcaagacaag
     3001 gtatcttttt ttcatttcta ctcctttatt tctaatagtt tatctagttc tgacgataaa
     3061 cgtttgacta attgtttaat ctcatccgat tttgcttggc aggtttctgc tgtcatttct
     3121 tcaaaaggaa cccaccagac tggaccacgt ccattgagac cgtgaccatt catgtcacct
     3181 gttcgtctag gaaacagatg ccaatgaaga tgggcatcgc catttcctag cagttcgata
     3241 ttcattttct cagcagtaaa ggccttagca actgcctctt ggactagact catttcttcg
     3301 agaaaacgta gtcttgtttc cttttctaaa tggtgcaatt ccgtgacgtg ttccttggct
     3361 agaaagagac tatagcctgc aaaatactgg tgatctccaa tcacaagata gcctgtttcc
     3421 aactctttga caaaataggg attttctccc ttcttgatga gctcaattct ctggcatata
     3481 agacacatat tagtctacca acgcgctctt aatgtaagca tcaaccatac gctctgttgc
     3541 gaccaccgag tcaatatgag tacgctcata agaatgacta gactcgatac ccgcgccaag
     3601 gagggcgtgt ttgacctctg cccctgcgga catggccgct gaagcatccg aaccataaaa
     3661 tggatagatg tccagcttaa aaggaatatc ttgctctttc gccaaggtca ccaaatgttg
     3721 acggaagtca tagtgataag ggcctgaggc atccttgaca cagatagaca ctgtgtactc
     3781 atctgtttgc tggccatcgc ccatagctcc catatcaaca gccagatatt cgactacctg
     3841 agcaggaatg ttagaattag caccatgtcc tacttcttca aaaactgaaa aagcaaaatg
     3901 agttgttact ggcaattcaa ttttctcttt cttataaata agaagcagat taagcaaaat
     3961 tgctgcactg accttatcgt ccaaatgacg agacttgata aaacctgcct ctgtcacgac
     4021 agttcgtgga tcaaagctga taaaatcacc gacctcaatc cccaaggcac gagtttcttt
     4081 ttcattgctt acttttgcgt ccaaacgtac ttccatatta tcctgcgtgc gttctgcagt
     4141 tcctgcatcc ttgtagacat ggcaagaagt ttggtggatg aggatggtac ctgatacctt
     4201 ttgacctgtg ctagccacat gaatggtaca gttttcacct tcaatcatat tccaaggaaa
     4261 accaccgata cggtccattt tgagacggcc atctggtttg acagcacgaa caatggcacc
     4321 taacgtatcc acatgggcag tcacatagcg atgctcttca tcattttgac ctttgatggt
     4381 cacattgaca ccacccttgg ctgtgcgaac cggctggtaa ccaaaacctt ctagagtctt
     4441 gactaaataa ttcgaaattt cacgagtgaa gcccgttggc gatgcgatgg ctgtcagttc
     4501 tttgatatat tttactgttt gattcatttc ttcacctctt tcgctaccta ttataacaca
     4561 tttatcatcg gataaaaaaa gaaaatcact cctgtagact tggctacaaa agtgatttaa
     4621 gtgattattc catttcaaaa acatcgcttt cttgcttgtt tggtagaacc aatgagagca
     4681 agattccaac aatggctggc accaaccatg ggagagatgc cttggcaaaa ggaagaacgc
     4741 taacaagatt tgcaagaaac tcaaccttaa acgagcttcc tagtacgctt gcaatggcaa
     4801 taactgtaac cacagcaatt gtcaactgca tacctggttt tgaaagggca acaaatttgt
     4861 tgaccatgac aatcataacg atagcaatcg tgattgggta caagataacc agtactggaa
     4921 ttgagtactt gataatcgca tcaagaccca aattggcaat agcaaatcca atcaaggtaa
     4981 aggctgtcgc ataaaccttg tagctgattt gtgggaagcg ctcattaaag aactcagctg
     5041 ttgacacaat taaaccaaca gtcgttgtga agcaggttac ggtaaccata gctgcaagga
     5101 agagttgagc tgttgagcca aagatttctt gagtggcttg tgacaagatg taaacacctg
     5161 gtgttccacc cttcatcgct tcagctggta ctgggaaatg atttccaaga aaacctaaac
     5221 cgatgtaaag agcgctgaag gcaagggcaa caacgatacc aacaacccaa atagttgaaa
     5281 tgtattcttt cttacttgaa aatccaagtt gtttcaaggt ttgaactgcg attacgctaa
     5341 aggccactga ggcaagggcg tccaaggtat tgtaaccttc taggaaacct gtaccaaagg
     5401 cagaagcttg ataagcagct gaagcagctt gaggacttgt tccaccatat ttgatagctc
     5461 ccagaacgac caagataaca atcaaaattg caaagactgg cgttaaaata cgtccaatgc
     5521 ggtctaagat ttttgatgga ttaagcgaaa tcaaataggc tgccgcaaaa tacagaaccg
     5581 taaatacaat caagccaagt cctttatttg catccgacaa aagggggcta atccctactt
     5641 cgtaagctgt tgtagcagta cgtggggtag caaagaatgg accgattgac aagtaaagaa
     5701 ctgagaggta aagagtcgca aaccaaggcg ctatcttcgt tgaaatctcg tagatatatc
     5761 ctttaggatt tagcgttcca ataataaggg tcaagacggc gataccaacg cctgaaaaga
     5821 caaaacctgc gatggcagga agaaaatgtt ctccagatag agcacctaga gaaggcggaa
     5881 aaatcaagtt ccccgcacca aaaaatattc caaacaggag caaacctgtt agggtacctt
     5941 ttttagccat aaaaatctcc ttcatattta taaaatactg acctagtata ccacaattag
     6001 gagtctgaaa aaagtatcac gaggcaaata ttaaatgttt tcaattttct taaaaataag
     6061 aattatctaa aaataaaact ctcctaccca gtccacacca agtaggagaa atgcaaaatt
     6121 ttaaagttct tcaaagacta acatgccacc ctggacattg ataacattat aaccttgttc
     6181 taataggaat tggcaagcac gcgccgatct cattccagat ttgcaaataa tataatgcaa
     6241 gcgatctttg tccaattaat cataactatc agccaattga ctaagcggta ggttgcgggc
     6301 accttctaaa tgaagagctg caaactcatc cacttctctc acatccacta gagaaagctg
     6361 gtcgttttgg taaagctggt aaaatgcgtc aaaggctatt tctttcattc tttttcttct
     6421 aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtgc gtatgttacc
     6481 gacttcgtca gttttatctg caacctcaaa gctgtacttt gagcagccta cgactagctt
     6541 cctagtttgc tctttgattt tcattgacta taaaatggtt ttaattcttt ttttcaaatc
     6601 tggcactact tctgcctcaa accaaggatt tttggccatc cagatttgat ttcgtggtga
     6661 tgggtgaact agcggaaaat aggctggcag atagtcttta tagtgtttca ccctctccgt
     6721 taccttccca ctgattttct cctgtaaata gtaggcttgg gcatattgcc caatcaagag
     6781 ggttaactga atatcaggca attcctgtaa gagctgcgga tgccattttt ctgcaaaacc
     6841 tgtacgaggc ggaagatcac ccgacttgcc atgtcctgga aagtagaaat ccataggcaa
     6901 aacagcaaaa taacctgaat tgtaaaaggt atcttcatcc acacctagcc agtcccgcaa
     6961 gcggtcacca cttttatctt tccagtaaag gcctgcttct tgagttttaa gtcccggagc
     7021 ctgaccgatg atattgatgc gagcagtttt tggcgctgca aagagaggct caatgccacg
     7081 ctctgtatag ctggcattct gtgaatccgc catgatagcc tgtttgattc tttcgatttg
     7141 agacatctac tttccctcca aaaagaagtc caagcataag atctcagact tctatcgttt
     7201 tatttgatca attcgtaaat agcttcggca taaattgctg ctgctcggaa aagatcatcc
     7261 aaggcgataa attcattggc ttggtgcatg gtatcaatcg agtctgggaa catagcaccg
     7321 taggcaactc cgcgttctag caagcgacca aaggttccac caccgatgac ttgttcatga
     7381 cctttaaggc cagtttgttt ttcatagaca ttcaacaagg tttgcacaag tggatcttcc
     7441 attggcacat agtgaggcgt gtgaccgtgt tcagacaggc taacagaaac aactggcaag
     7501 ttttcaagga ttgacttgat ttgttctgga cttgttcctt ttggatagcg gatgttgagg
     7561 gcaatggtat tatcagcact tgtttcatcg aagcggaaga cgccggcatt catagaaaga
     7621 gcacccatct tttcatccac atgagcaatc ttaagatttt caccctcatg atcgttcaag
     7681 agaattttac ctgcgatgtc aaggtagtct ttggctggac cagcaaagcc aaactggctg
     7741 aggaagaggg caaggtaagt tgcgccattg acacctgaag caggcatagc accgtgggct
     7801 gatttaccaa tgatcgtcac cttgtatttg ccagcttctt cttggagttc tcctctaagt
     7861 ttgtgttctg caacaaaggc atctagttta gcttgcaagt cagccaagtc acctgaaacg
     7921 actgctgttg ctgattctgg taccatattt tcacgtaaac cacctgtaaa gctgtgaaga
     7981 cgggcaacac ctgtattttc tcctgcaaag tggaggtatt ccgtgatatt tcctttttca
     8041 ccattgatga ttggaaattc agcatctggt gagaaaccga aatctggttt ggcaagtcct
     8101 acgtgctcaa agtagtagtc catgtctgcc cagcctgatt cttcgtctgt tccaacgatg
     8161 aagcgaactt tcttagaagt tggaagaccc aattctttga tgattttcaa accatagtaa
     8221 caagctgttg taggaccctt atcgtccgaa gccccgcgcg cataaaggcg accatctttg
     8281 atagttggtg tgtaagggtc tgtgtcccaa ccgctaccag caggcaccac atccatatgg
     8341 gcaaagattc cgagaacttc ttctccatca ccaaactcaa aatgtcctgc atagttatca
     8401 acattcttag ttgggtagcc atcgcggtct gcgatttcaa ggaatttctc caaggctttt
     8461 actggaccag gcccaaatgg atgctgggca tcagccttgc tgtcatcacg ttctgaattg
     8521 atttccaaaa ggctaaacaa gtcagccaag aggtcttctt tgcgtttttc tacttctgct
     8581 gtaaaatcaa ttgctgtcat tttttcttct ttctatcttt tctcgatgat ttcatctact
     8641 ggcaagcggt agcttggttc caatttttcg tctgtataac ccactgtgat caagagttct
     8701 gggcggaaac ggtcttcgat ttccaaaact tcattaactt ttgatttgtc aaaaccaaga
     8761 ataatgttag aaccaattcc ttggtctgtc aatgcaagaa ccaagttcat ggcaaccaaa
     8821 cctgcattga gagctaggta gtcgctgact tgttgctcac tgtaacgggc aaactcagct
     8881 ggcagatttt tcataaaata ttgaagttgc tcttcagaaa agttattagc accaccaaca
     8941 cgggcaatct tacgagcacg tttggctaag tccgtatctg taaacaaggc aatggttaca
     9001 ggcgctgatg atacctgttc aaaattggaa ccataagcta actttgccag ttcagcattt
     9061 ttctcacgta ccaccacaaa tttccaaggc tggctgttgt gggcgcttgg cgccaaggtt
     9121 gcaatttcga tagccgtacg cacatctttg ggatcaacag gcttatcagt aaaatgctta
     9181 gtcgcatgac gttttttatt taattcaaga aatttcataa tcgatttcct tttctaattc
     9241 tactgcttcc attctaccat aatttgaaag agcttgcagg gatttttcat gattaagttt
     9301 ttctatcaca gacataaaag atatatattg gtttatcagg aaagtttctg ataaactagc
     9361 aagtacttta catttgaatg gagacagtat gaaaaaattt agcctattac tagctatcct
     9421 accatttttg gttgcctgtg ggaatcaagc tacacccaaa gagactagcg ctcaaaagac
     9481 aatcgtcctt gctacagctg gcgacgtgcc accatttgac tacgaagaca agggcaatct
     9541 gacaggcttc gatatcgaag ttttaaaggc agtagatgaa aaactcagcg actacgagat
     9601 tcaattccaa agaaccgcct gggagagcat cttcccagga cttgattctg gtcactatca
     9661 ggctgcggcc aataacttga gttacacaaa agagcgtgct gaaaaatacc tttactcgct
     9721 tccaatttcc aacaatcccc tcgtccttgt cagcaacaag aaaaatcctt tgacttctct
     9781 tgaccagatc gctggtaaaa caacacaaga ggataccgga acttctaacg ctcaattcat
     9841 caataactgg aatcagaaac acactgataa tcccgctaca attaattttt ctggtgagga
     9901 tattggtaaa cgaatcctag accttgctaa cggagagttt gatttcctag tttttgacaa
     9961 ggtatccgtt caaaagatta tcaaggaccg tggtttagac ctctcagtcg ttgatttacc
    10021 ttctgcagat agccccagca attatatcat tttctcaagc gaccaaaaag agtttaaaga
    10081 gcaatttgat aaagcgctca aagaactcta tcaagacgga acccttgaaa aactcagcaa
    10141 tacctatcta ggtggttctt acctcccaga tcaatctcag ttacaataac actcttcgaa
    10201 aatctcttca aaccacgtca gctttatctg caacctcaaa gctgtgcttt gagcaaccta
    10261 cggctagctt cctagtttgc tctttgattt tcattgagta taagatatac taaaagcgat
    10321 tggaccagcc aatcgctttt ttagtttgca ttggctattt taggaaactc ttacaaaaaa
    10381 tcaaaaaaat tcttcacatc ctctacatac ccatgctttt ctattaagct ggctaataat
    10441 tccagattgt gcccctgata gttatcgtca cgacgcagtt cttcatacat ttcgataaag
    10501 ggaagcccct tggacttggc caattctaac tcagcctcgt aatcataagc aactttacga
    10561 aattggatat tgaccaattc cccatcttca acttctatca cggcatactg ggcacggtga
    10621 ttttttaacg cctcccaatt aaaatagggc atgccaatcg accctggatt gatgatttgt
    10681 tgcccttgac ttccataacg aagcaactgc ttgtgaacat gaccataaac tgccacgtcc
    10741 gtttccgcat ctagcagttg gtcaaatttc tctgtatcat tctcaactag caagtcacca
    10801 ccatagttct tatttggcaa attatgagag atagaaaagc gcagtccagc aatttctttc
    10861 ttttccagca aaggcaagct tcgtagccag acagtcgttg caggatccat tcgctccatc
    10921 aaaaactgag tcattcgcat gagctggatt tcctgtgggt cttctaagcc atattgccca
    10981 tctaaagcct caaggacaca atcatcccaa ttgcctcgaa cacttgccgt gataggaagt
    11041 tcctttaaca gagcgaccaa gtcatttgca cctgaaccag ggaggaaaat gtctcccatg
    11101 agccaatatt cactggctcc ttgagtttta gcatctgcaa tcactgcttc tagcgccgtc
    11161 gcattgccat gaatatctga taaaattgcg attttatggt ttattgtggt ttccttccgt
    11221 ttggtaatct actctttctt ccgccacttg aagcaagatt tctgtttcct gcgggttcaa
    11281 ctttctttgc acagcctctg ctactgctct tggtactcca acttcgacaa tctcatccac
    11341 actggcttcc ttgattttgg tcagagactt gaagtgcctc atgagatttt gcttgcgttt
    11401 aggtcccaga ccatcaatcc catccaattg agatgagaaa gaatttttgg agcgcagttg
    11461 gcggtggaag gtaatggcaa agcggtggac ctcatcttga atgcgttgga ggaggaaaaa
    11521 ttcctgagaa ttgcgagaca agtccaccac ttccagcgga tctccaaaga gcaattcatg
    11581 ggtttggtgc ttatcattct tttgcagacc tgcaattgga atatccaagc ccagttcttc
    11641 ttggatgact tgcttagcaa tattgacttg accttgcccc ccatcaatca caatcaaatc
    11701 tggaggagtc aaagcctcac gctgtactcg accatagcgt cttcgaatga cttctctcat
    11761 actagcatag tcgtccggcc caacaacggt ttttatcttg tacttacggt aatctttttt
    11821 acttggcctg ccgttaacaa agaccaccat ggctgaaaca ggactggtcc ccatgatgtt
    11881 ggagttatcg aaggactcga tgcgaactgg agtcggaatt tggagcaaac gtcctagatt
    11941 ttcaatagct ccttgggtct tttcgactga tttttctagc aggttaaatt tctgctccag
    12001 actaacacgt gcatttttta tggctagatt gaccagctgt tttttctctc cacgttgggg
    12061 tttgagaatc ttggtatcca ccaaagcctt gacagcttct tcgtcaatat cctgcggaat
    12121 cagtacctca ttgggaacta ggtgagattt ttcttgatag aattgtccca cataggtcaa
    12181 gaaatcctca tctggatcat tgaagtaagg gaagagattg acatcgcgct cgatgagctt
    12241 tccctgacga acaaagaaaa cctgcacaca catccagccc ttatccacat agtagccaaa
    12301 gacatcgcga ttttggagat ccttagccat gacccgttgc ttggttcgaa gcgttccaat
    12361 agcctgaatc aggtcacggt attccgccgc acgttcaaac tccatagtct gggctgccgc
    12421 tgccattttg ccctttagct catcaatgat tttgttatcc tgccctttca gaaaatcaga
    12481 aacctcctgg gccatagact tgaaataagc ctcatccttc ttacagatgg tgtgagccat
    12541 acactggccg atatggtaat aaaaacagac cttagagggc gggttggtac acttacgaaa
    12601 agggaatatc cgatccagca accgcttgat ttcattggct gcccccacat cgggataggg
    12661 tccaaaataa agacctccgt cctttttgac ctgacgagtg ataatcaagc gtggatagcg
    12721 ctcattggtg attttgatga aaggatagga cttgtcatcc ttgagcatga tattgtactt
    12781 gggcttgttt tccttgatca ggttgatttc taggagaagt gcctcaatat tagactccgt
    12841 aacaataaat tcaaaatcca caatttcaga caccagagcc tctgtcttgg tatcatgact
    12901 tccacgaaaa taggaccgta ctcgattacg cagattttta gcctttccta catagataat
    12961 ggtgccattt ttatccttat gaatgtagca accagggctg gtcggcaaga gctctagttt
    13021 tgatttaatc aagttgttca tagttccatt atagcaaaaa aagtagggaa agatagtacc
    13081 ctactcacta gtctcatata tttttcggag gtttgcaaca tcctcttcct ggataccata
    13141 aaaggaacct gctggttgca tgacagactt ctcatctgta tggtccaagc caatcgcatg
    13201 acctaactca tgttctgccg tatggacaag gcgttcatag gagtagccat agtatggatt
    13261 ggacaaataa taatgattca accgcaccgt tacggacaag aattgccctg ttaagagatt
    13321 agtttgactt tccgcctctc ctgccacagg agtgcctccg tcgttcatct ccgtagccgt
    13381 aatatccgcc ttactagact cagtcacgag ttcaaagtta aaagcaccag tttgattcca
    13441 gttctggatt gcttctaaat aagcctcttg aaagcgtgaa tccatctgcg gatccaggta
    13501 aatacgagca gaggcctgtg cccaccttcc ttcagaatgc tggtgactat ctgtctggct
    13561 taacttaggc agttgccctg ttttctccca ttggtcaata ctttgttgac caatttttac
    13621 tgaccgttct gcttgcttta gcgctccttg aaaatccccg ttcagatacc agagaagtcc
    13681 gaaagcaagc acacataaga gcacaactat ccaaaccaga cgccaaaaca aacgccacac
    13741 aaaagaaaag aaagccccta tcaaacgaaa aagccagcgc atgtctctcc acctttctag
    13801 caaataagaa ttattttact aaaagaagct aaaagaaatc taaatactga ctttttcatc
    13861 ttaacgtcct actatttttt tgagtaactg gatagctttg tattttaaag gcgatggatg
    13921 gtaacggaaa gtacccgctt tgcgtacaat atagccatta aaattctgtt taaaacgcaa
    13981 aacaccatca cttccatcaa aaatcccttg aatgcctagg aagttgtatt taggtattcc
    14041 acgttttatg ctttccaaca taacatattt ttgaagcagg gcaggggcat agaacttatt
    14101 aaactcagtg taggaaccac taaagagata agtcgtttcc tgaggcatat aaacaaataa
    14161 actcccagct aaaacaatat cttcttctcc atatttttca atcaagtctc gcgcttctgc
    14221 ttttcgaact tcaaacgttt caaattgact agaatattct ctcagttgat tttgtttttt
    14281 ctcagaatga ggatttttac tcaaatcaag tcgcaacttg tccaagtttt cttctagttt
    14341 actttgttca ccttgcaatt tgctcatata gtccgaaaaa tttaagcttg ctatgagaaa
    14401 ctccgcttgt tctccaaaag tatcataaaa atgctcataa tattctaaac ttttatcact
    14461 atattctcta cgttcagagg tttcttttgt tatattctta aaaatcgata gttcttcacg
    14521 ttttaacttt ttcaaccgaa tgccaaaggt ttcagccttt ttcaccaagg gtttaccctt
    14581 tttgctaaaa cttttaagca aactcttttc agttaattca gttaaatctt tatagtataa
    14641 ccaatctggt tctccacctg ggtaacctgt tgttaagcca tcaaattgat aacctaaatc
    14701 agtcaaacct tgaataatac tttttttctc agcatctatt ggattacctt ggctatcaaa
    14761 agtttgataa gtttcataag gttttacaag caactctaat acaccatttt gcttggcata
    14821 ttcttttaac tctgcataaa aaactggaag agcatcttgt tgggtataaa tcggccccga
    14881 attgagttcc atatgcagac cacccagcat gggcaagcta taaaccagag ctgcaacttg
    14941 aatttctcct tcttgtttca aagcaagata aacaattcga gcccctcttt tttctagcaa
    15001 atcccccatc tggacagatt gcataaagga acgagaagaa acctgatcag aataagtctg
    15061 aaactcttct ttcgtgagtg ttgttagtgc catatactta ctttctatgt ttttttctta
    15121 atgttttacg gaaatcaaga gcaagtctta acagaggata gagaggatga gtgggcattg
    15181 taaattcacc caagtattct tcaatcgttg gattaaattt ttccttaaaa tgataaagtc
    15241 caccattgag agagttttca acaccaccta aattttgcca gatcatacct cgttcaaagg
    15301 catagcgagc cgtttcatac caagttaaaa ttggtgcatt gtaacgttta aaatcatcat
    15361 ccataccagc atatatattg acagaggtag taccaaattc caaactcaaa gtagccgcta
    15421 aaggaactct cgcttgacct acatctatat attcctgcaa gaaggtcaat tcctctaaca
    15481 aacgttcttt ttccttcttc tgcgcttcta cttttgaagt tcgagtcgac tcagtaaagg
    15541 tctcttccaa ggctctattt ttcgctaact gttcttctaa ctcttgcgaa cgtttagaaa
    15601 catccaaggt ggccaaggtg atataggcct tgtccttaaa attatctaac aattttttat
    15661 aataggcttc attcctcaaa tgaatctctt ttcgcttctc agtttttttc atcaactccg
    15721 aaaatgaatc taatagttcc agtccaccat attgaatctc aagccctttg tttcgtgctg
    15781 ttcgaatagc ctgttttgtt gacttggaaa gtttatcttc ttcaaaattt tccttgtata
    15841 ttttcgcctg aatacgaggt tgaatggtgt ctcccatttc ctccgttttt cctgaccacc
    15901 ttactcccat ttgttgcaaa ctatcaataa tagccagatt ttcaggaaat tctgtctttt
    15961 cctgattgat taaactttga gataggcaaa tacttgggtc aaaagtcaca aaaaccactc
    16021 tcttactgcg agcataggac ttaatagact gaatggcaaa attcaagagt tctttatccc
    16081 cataatccaa tataggtcct cttgggatgt aaaacatttt atagcctagc ggaagagttc
    16141 taatcaaaat actagctgtc gccagtaatt tttcttccct gtaaacacca aacttctcat
    16201 gttgccaatt agacttaact tcctcccaag cactactttg taatacattg gctaattcat
    16261 gttctttgac aaactgatca tattctaatg tgggaatgcc aatttgataa cggtacattt
    16321 cctactctct ttcctccagt attttattac tattctacta ctttcgtttg aaaagtctag
    16381 tgaaaacata ttttatttta gttctactcc ccctatgctg aagttcaaac taagtcagtc
    16441 tctcttctaa tttgaaatca attggtaggg ttgttaaaaa aacttccaat tgtttttccc
    16501 agtagtacca ctcgtgagtt ccagcgctat ggctataggt cacatcaaaa cctagttttt
    16561 tgagattttt cactgcgaga ttattggctt cgtacaagaa atcctgttcg ccacaccacg
    16621 cccaaagttt ggtcttttta tccgattttt tagccagact ttcaagagaa tagggactag
    16681 ttgtccagtc tctaatctct ccaaaaacac ctctccagta ggctggactt cccagatttt
    16741 gactttcagg agaaaagttt tgaaagctga gggcacctga aaaactagct gcatgagaaa
    16801 aacgatttgt cgtaagagcc agtttgaagc agccgtagcc tcccatagaa agaccagcga
    16861 taaaggtctt ttcacgcttg ctcgtcatat tagggaagaa gcgtttcaga acctgtggca
    16921 attcctctgc tagagccgtg tagtagtcaa aaccatactg ggtatcggtg taccaaccat
    16981 tgctggtatt gggcataaca acgatgagat tagttcctcg aagcaagcgt tctacattgg
    17041 tccgcttaag ccaactatta tgatttccag acatcccgtg caaaaggtac aagacgggaa
    17101 tatcttcaca ctctggttct tccactcgat tggcatcagg gtagaggaca ttcacccccc
    17161 actccatatc caatacttgt gagtaatact cgattttcat tactgccatg attttctcct
    17221 tctatttttc tataagaaaa agccgaaact cgactttctc tctgtttatt tcaacgatta
    17281 ttttgcttcc atgactactg gtaaaatggc tgggcgacgc ttggtttgat caaagaggta
    17341 cttggtcaga ttgtcacgaa ccttaccttt gagatctgcc cagtcaaagt catctccttg
    17401 aagatactct tctaccgttt ggttaatcaa ttctgaactt tcacggagaa tatcgcgact
    17461 cttcttgaga taaacaaatc cacgcgtgtg aacacgagcc ctagccacaa ttttcttctc
    17521 acgacggttg actgtaatag ccacgatgaa aattccatcc tctgacaaga ccttacggtc
    17581 acgaagaaca acatttccaa catcaccaat ggcattccca tcaatcaaga tatctcctgc
    17641 tgaaaccgat ccagctggaa tgaagtctcc attctcgtaa gccatggtcg tccccttttt
    17701 aggaatgaag atgcgttctg gcaacatccc aactgccatg gcagccttag cgtgagcatc
    17761 caactcacga tactcccctt ggacagggaa gaggtactta ggttgcaaaa gattgatcat
    17821 cagctgcaaa tcacgcacat ttccgtgccc tgatacatgt aaactttggg taatcaattt
    17881 gacaacccca cctgcctgat aaatcatatt ttccacacgc gcaacaaagg cttctttagc
    17941 aatagacgga gccgtagcaa tatagactag gtccccatcc ttgatttcta cataacgatg
    18001 gcgaccaatc gacatcttac gaagtccatt gataggctca cccatacgac ctgtctcaag
    18061 aataatcaac tcatggtctt caaagcgaga catatcttta ggcttaatca aaagaatttc
    18121 gttggctaaa gacaacttct taagacgaat cgctgtgcgg acgatatttt caatatcaaa
    18181 tcctgtcaag acgatacgtc gacctgtttt atccgcagcg tcaaaaatct gctgaatacg
    18241 agaaagatta ctggaaacag ctgcaacgat gatacgacct tcccagtcag caatagtttg
    18301 ggtaatttca tccctaactt cactttcact agccacctga atattgctgt ctgcattggc
    18361 cgaatcactg aggagagcca ggacgccgtc acgaccaatc tctgccaaac gagcaaaatc
    18421 agttgcataa gattcactag ccgtttggtc aaatttgaag tcacctgtat aaacgatgct
    18481 tccttccgat gtcttcaaga caattcccag actctctgga acggagtaag tcgtagggaa
    18541 gaaggaaacc actgtcccac caaaatcaat ctccgtattc tcatcaatga catggaaatc
    18601 attaaatttc ttaacggcat catttccttt gacaaagagc tttgccaact caatggtcaa
    18661 ctcagaccca aatacaggaa ctttagcctc tgccaagaga tacggtagag caccaatggc
    18721 atccgcatgc ccgtgggtca agaaaacccc agcaatacgg tcgctatttt caaaaaggta
    18781 atccatgttt ggaatcacca catcgacccc taattgttca ttttcaggat attttaaccc
    18841 tacattcaaa acaaaaatgg actctccaat ttcagcaatg tacatatttt ttccattctc
    18901 acgcacacca ccaagtgttg ttaaactgat attactcatt tttcctccaa aatcttagtt
    18961 tatcttgatt atagggcaat tctaccctct tattctaaaa gttctgatac tttcagccga
    19021 atcttttcct accattatac catttttttg atgattttca aaatgaaggt ctgttttcaa
    19081 aaaagagttg atttcccaac tctttcctaa cttctactct ttttccatca aaaaatcata
    19141 aatttcttgc accgtaccca gcgccatcat ttcttggtct ttaacggttt gtttgagatt
    19201 ttggtaaatt tgactttctc ctatctcccg ctttggcgcc tctttattga ctgtcatcac
    19261 accatctttt atcgtcacaa agcctagttc ttcaaatact tgaatcatct tgaccagcaa
    19321 gatttgttga atattaagat atgcagccaa atctttcagc ttgtagcgaa tatcaaactc
    19381 tgggaactgg taaatagtct tgtacaattt ggcaaactga tctctagtcc cataacctgt
    19441 cagataatag gccttgtcaa tatcattttt gaaatagaca gcagagaaat gctgttcctg
    19501 aaaaatggtc ttcagctgag taatatcctc tggaatgttt tttacgacaa tagcttcact
    19561 agccgcaaga tttggcagtt ctccaggaaa atccaagact ggaacacctt ctggcaagac
    19621 tgcatttttt ccacgaatgt taaaaagttg aacaccttcc actcgcgcat ccaccatcat
    19681 caactggagg gcagtttggc cattccattg gttgacagac aatttaaccg ctaactctag
    19741 attcttggtt tgagaaaact ctgtcgccca tctgccttga ccaaaggcta ccacttcaaa
    19801 actcgcctca cccttggaaa ttttcagctt tagatgggca ttacctgccc ccatagtacg
    19861 agcactttcg acctgaaaat tcttgatata aaaaataggt ttctgattat ccattccaaa
    19921 aggagctaaa cgttcaaaac ttttgaccgt ttccaagcta agtgcctcca aatccaactc
    19981 ttcatctagg tttaacttat tcttgccacc agcatctgca cctttttcac gaacataatc
    20041 ttccaaaacc tgagataaat ctgagagttg ctcaacttcc agcgtcatac ccgctgcacc
    20101 tgcatgacct ccaaaggcga taaagaggtc tcgatgggga tccagagctt caaaaatatc
    20161 gaccgcttcc acactacgag cactgccctt ggcacgaccg tcttctatat taagaacaat
    20221 gactgtctgt cccaattctt ccaataaacg accagccacg attcctagaa ccccaggatt
    20281 ccagccttcc ttggccaaga cctgaacctt cttctcagga tccaccatgg tcttggcttc
    20341 ttcatagata gactgaacga tttccttgcg ctcttcgttt ttctggtgaa tcataaaggc
    20401 aatctcatgc gcttcctcat catcaaatcc agtcaacaaa tcaatggcag gattgggatc
    20461 atccaagcga cccaaggcat tcaaacgagg agcaatctgg aaaccaaccg tttcttctgt
    20521 tacttcgttg gcagcaatcc cagccatgtc cagcatttct tgcagaccaa tgcgctgggt
    20581 atgacccaac atttccagac catattgaac taagatacga ttttcatccg tcagactcac
    20641 catatctgca atagttccaa tagcgaccaa atcaagcaat tccacttgca cttcttctaa
    20701 cagggcacaa gccaacttga aagcaactcc acaaccagcc aaatatttaa aaggataatc
    20761 cgcatctgga tgttcaggat ggacaatagc ataagcatct ggcagggttt caggcatgga
    20821 atgatggtct gtcacaatga catctactcc catagactga gccaatgcaa tagcctcatg
    20881 accagcaacc ccattgtcca ccgtcacaat caaggaaatt ccttcttgct cgataaagta
    20941 tttataaaca ctagcattag ggccatagcc atcggtaaaa cgatttggca ggtaaactcg
    21001 gcactcagca ccaagttgtt ccaaactttc cttcacaata gaagccgaag tcatgccatc
    21061 cgcatcatag tctccataaa cgagaatatt ttccccttct tcaatagcct gacgaatccg
    21121 ctccactgcc ttgtccatat catggagcag ataagcatca tgtaagtcct ccaaggaagg
    21181 ttctaaaaac ttcttcagac tttcttggtc ctgaatccct ctctcaaaca ataaccgagc
    21241 cacctcagga cccagtccag ccttcttggc tatctttgta aaatccgcat cttctacctg
    21301 cagggcaaac tgccattcat aagtaggtgt tatcaaaaag acatccactc tttctaagaa
    21361 ttctattgct tcattataac atgatttaga cgttttctct atccagattg cttttttata
    21421 acattttata gtatattgaa actagaatag tacacctcta cttctaaaat attgttagaa
    21481 atcgatttga ctgtcccgat cgatttgtcc tgttcttatt tcactatagt gaattttttc
    21541 agatatggtt tgacaagaac attcttttat tgtagaatcg tgttataaaa tctaacacaa
    21601 aggagatctc tcatggcttt agtagaattt aaaaacgtcg aaaaatatta cggagactac
    21661 cacgcactcc gcaacatcaa tctccgtttt gaaaaaggac aagttgttgt cctgcttgga
    21721 ccttctggct ctgggaagtc cactcttatc cgtacgatca atggtttaga gactgttgac
    21781 aaaggaagtc tcctagtcaa tgggcaccaa gttgctggtg ccagccagaa agatttggta
    21841 cctcttcgca aggaagtcgg catggttttt caacatttta acctttatcc acacaaaact
    21901 gtgttagaaa acgtaacact tgcacccatt aaagttctag gaattgataa aaaagaagct
    21961 gaaaaaaccg cccaaaaata tctggaattt gtaaatatgt gggacaagaa agattcctat
    22021 cccgccatgc tatctggtgg acaaaaacag cggatcgcca tcgctcgtgg tcttgctatg
    22081 catccggaac tcctcctctt tgatgaacca acatctgctc ttgatcctga gactatcgga
    22141 gatgttctag cagttatgca gaaactggcg catgatggga tgaacatgat catcgttacc
    22201 cacgaaatgg gctttgctcg agaggttgcg gaccgcatta tctttatggc cgacggagaa
    22261 gttttagtag atacgacaga tgtcgataac ttttttgaca atccaagcga acctcgtgcc
    22321 caacaattcc tcagcaaaat tatcaaccac gaaagtgaca aagtcaaata aggaggcgcc
    22381 tatgaaaaaa aaattctttt tatcagcatt attgattagc cttttcggcc ttgctgctgc
    22441 caaaccagtc caggctgata ctagtatcgc agacattcaa aaaagaggcg aactggttgt
    22501 cggtgtcaaa caagacgttc ccaattttgg ttacaaagat cccaagaccg gtacttattc
    22561 tggtatcgaa accgacttgg ccaagatggt agctgatgaa ctcaaggtca agattcgcta
    22621 tgtgccggtt acagcacaaa cccgcggccc ccttctagac aatgaacagg tcgatatgga
    22681 tatcgcgacc tttaccatca cggacgaacg caaaaaactc tacaacttta ccagtcccta
    22741 ctacacagac gcttctggat ttttggtcaa taaatctgcc aaaatcaaaa agattgagga
    22801 cctaaacggc aaaaccatcg gagtcgccca aggttctatc acccaacgcc taattactga
    22861 actgggtaaa aagaaaggtc tgaagtttaa attcgtcgaa cttggttcct atccagaatt
    22921 gattacttcc ctgcacgctc atcgtatcga tgccttttcc gttgaccgct ctattctatc
    22981 tggctacact aataaacgga cagcactact agatgatagt ttcaagccat ctgactacgg
    23041 tattgttacc aagaaatcaa atacagagct caacgactat cttgataact tggttactaa
    23101 atggagcaag gatggtagtt tgcagaaact ttatgaccgt tacaagctca aaccatctag
    23161 tcataccgca gattaaggag gataccctat gacagattta tcatcttgga cagcctattt
    23221 tcaggatttt ggacaatttt tcaatggttt cctctttact cttgccctag cgattggatc
    23281 ctttatcctc gccatggtct taggaatctt ctttggtgcc atgtcaacca gtaaacgtcc
    23341 aattttacgc attttagctc gcatctttgt tgaattttac caaaatactc ccctcttggt
    23401 gcagtttgtt attgtttttt atggcctacc tcttatcagt gaccatatca tcatgattcc
    23461 aatttattgg acagccgttc tctgcgtggg actctatcac ggcgcttata tcgctgaggt
    23521 tattcgttca gggattcagt ctattcctag tggtcagatg gaggccgcct tgtcgcaagg
    23581 ttttacctat atcagtgcca tgcgcttgat tatcttgcct caggccttcc gcatcattct
    23641 ccctccattg accaaccaaa ttgttaacct catcaagaac acctctactg tagctatcat
    23701 ctctggagta gacttgatgt ttgtgactaa gtcttggtcg gctctcaacg gaaactatat
    23761 cccagccttt ttaggtgctg ctcttctcta ctttgcccta tgcttccctg ttgcccagtt
    23821 tggtcgcaag atggagcaag ccaacaaaaa agcctattca ctttaggagg ttactatgga
    23881 atctatttta gaagttttaa ccccagataa cctagtcttt atctttaaag gatttggctt
    23941 gaccctctat atttctctga ttgccatcat cctctctact atcatcggta cggtgctagc
    24001 tgtcatgaga aatggcaaaa atcctgtctt gcgaatcatc tccagtattt atatcgagtt
    24061 tgtgcgcaac gttcccaacc ttctctggat ttttactatc tttttggtgt tcaaaatgaa
    24121 atccacacca gcaggtatta cagcctttac tctctttaca tcagcagcct tggttgagat
    24181 tattcgaggc ggtctcaatg ccgtagacaa gggacaatac gaagcaggaa tgtcacaagg
    24241 cttcacctca gcccaaatcc tctactacat cattctccca caagccatcc gcaaaatgct
    24301 accagccatc atttctcagt ttgttaccgt gattaaggat accagtctcc tctactctgt
    24361 tatcgcccta caagaactct ttggagccag ccaaattctc atgggccgtt attttgaacc
    24421 agagcaggtc ttcagtcttt acatcctgat tgccctcatc tacttcagct ttaacctagc
    24481 aatttctagc ctgtctcata tgctagccaa acgttggcaa caagctgcag aataatactc
    24541 ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaac ctcaaaacag tgttttgagc
    24601 aacttgcggc tagcttccta gtttgctctt tgattttcat tgagtataaa cagccactct
    24661 ccagttcaat tggagagttt tttgatgaga gtagatattt atagacctca atttgacacc
    24721 atacattttc tatgataaaa tgtaacaaat tcatttacaa caaatcgaaa tctaaatgaa
    24781 atggaatttt ctatgaaatc agtcaaagga ctactcttta tcatagctag ttttatcttg
    24841 actcttttga cttggatgaa cacttctccc caattcatga ttccaggact agctttaaca
    24901 agcctatctc tgacttttat cctagccact cgtctcccac tactagaaag ctggtttcac
    24961 ggtttggaga aggtctacac cgtccacaaa ttcacagcct ttctctccat catcctacta
    25021 atctttcata actttagtat gggcggtttg tggggctctc gcttagctgc tcagtttggc
    25081 aatcttgcca tctatatctt tgccagcatc atccttgtcg cctatttagg caaatacatc
    25141 caatacgaag cttggcgatg gattcaccgc ctggtttacc tagcctatat tttaggactc
    25201 tttcacatct acatgataat gggcaatcgt ctccttacat ttaatcttct aagttttctt
    25261 gttggtagct atgccctttt aggcttacta gctggttttt atatcatttt tctatatcaa
    25321 aagatttcct tcccctatct aggaaaaatt acccatctca aacgcttaaa tcacgatact
    25381 agagaaattc aaatccatct tagcagacct ttcaactatc aatcaggaca atttgccttt
    25441 ctaaagattt tccaagaagg ctttgaaagt gctccgcatc ccttttctat ctcaggaggt
    25501 catggtcaaa ctctttactt tactattaaa aattcaggcg accataccaa gaatatctat
    25561 gataatcttc aagccggcag caaagtaacc ctagacagag cttacggaca catgatcata
    25621 gaagaaggac gagaaaatca ggtttggatt gctggaggta ttgggatcac ccccttcatc
    25681 tcttacatcc gtgaacatcc tattttagat aaacaggttc acttctacta tagcttccgt
    25741 ggagatgaaa atgcagtcta cctagattta ctccgtaact atgctcagaa aaatcctaat
    25801 tttgaactcc atctaatcga cagtacgaaa gacggctatc ttaattttga acaaaaagaa
    25861 gtgcccgaac atgcaaccgt ctatatgtgt ggtcctattt ctatgatgaa ggcacttgcc
    25921 aaacagatta agaaacaaaa tccaaaaaca gagcttattt acgaaggatt caagttcaaa
    25981 taagtaatca tactctcctg ggatttccca ggagagtttt ttatagccaa atgaaataag
    26041 acaggaacga tggaattttg gcattcaaat caattgataa gaatgtttta tagtggagtg
    26101 aaataggata cgaacaaatt gattaggaaa atcaaatgaa tttatagaaa tcttttagca
    26161 gttatgttgt cctattctag tttcaaaacg ctatagaagc agcattgtgc tagtctagat
    26221 tcagtttact atactaaaac gagtagcttg aaatcaaaaa acccaccctc acaggcaggt
    26281 tttatctgta ttattcagct agattatgct ttaccttctg aaccgaatac gtcgatacgt
    26341 tcttcaaccg atgcttggat agcttttaca ccgtcagcca agaatttacg tgggtcgaag
    26401 agttttttct tgtcgtattc tgcttcgttt gcttcgtagt cacgagcaaa tttacgagtt
    26461 gcgttagcga atgcgatttg gcattctgtg ttaacgttaa ctttggcaac accaagtttg
    26521 atagctgctt ggatttgctc atcaggaata cctgatccac cgtgcaatac gattgggaat
    26581 cctggaagag cttctgtcaa tttttgcaag tggtcaaggt caagaccttc ccagtttact
    26641 gggtaaggac cgtggatgtt accgatacca gctgccaaga agtcgatacc agtttcaacc
    26701 attgctttag cgtcttcgat tggagccaat tcacctttac cgatgattcc gtcttcttca
    26761 ccaccgatag taccaacttc agcttctact gagatacctt tagcgtgtgc tttttcaaca
    26821 acttctttag ccaatttaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt
    26881 gaagtataac caacttcgat acactcaagt gcatcttcgt agtgaccgtg gtcaaggtgg
    26941 atagctactg gtacagtgat acccattgat tcaacaaggt tagcgatcaa gttgcgagca
    27001 actttgtaac cacccatgta tttagcagca cccattgaag tttggatcaa aactggagct
    27061 tttttagctt ctgctgcgcg caagatagct tgagtccact caaggttgtt tgtgttaaat
    27121 ccaccaactg cataaccgtt gtcacgggct gcttggacaa atttttctgc tgaaacgatt
    27181 gccattttat caggcctcct gtatattttt atgggtcatc ccatttacat tgttcatttt
    27241 atcacttttt gccaaaaaaa tctagttttt cccgcagttt cgattgattt tcttctaact
    27301 ccatctatgt aaaccctttc tctccctagt cttggacgac ttttggaaaa tctataaaga
    27361 aggttaaacg attctcctcc atctcgaaac gataagctaa tttttcatgt tctaatagac
    27421 tcttaaccac aaagagcccc ataccagacc ccttgacctt gcgactggca ttgtcagaaa
    27481 aagactgggc tagtttttct tgttcctctg agctacagct attttcgata aaaagttctc
    27541 cttctctttc tccaattcga actaagccac ctggaacaga gtgcttaatg gcattgctga
    27601 tgagattaga aagaatcaac ttcataactg atgggtttag ataagcctgc tgatgggtca
    27661 aactattgtc tatctggagc tctctttcct tggctagcaa ggcataatct ttgaccagat
    27721 tttgcgtcat ctggaggagg tcaattgttt ccctatcatc tcgcaattcc tgcacagaag
    27781 agagggaaag tatctgcaga acatggtgat tgagttcatc cacaatcccc aaggcaactc
    27841 ccagatactg gtctctatcc ttataacgac cgatattctc tctcatattt tcgattagga
    27901 ttttcaaact agccagcggt gttttcaatt catgagaagc tcctcgtagg aattcgacct
    27961 tcatcttctc cagctggaga atggcttcat tcttttcatg caagtccgca ataacagtca
    28021 agagatgctg gtagaggcta ttgatttgtt ccttgagatt acctatctca tccttagaat
    28081 ccacgcgcaa tcgcacttgg gcatccaggt acatcatccg acgagtcacc cgcttgattt
    28141 ccaaaatcgg tgcaacaata gtccgagcgt agatgtaggc caccaagagg gaaatcagaa
    28201 aggaggccag caaggtatag ggaagaaact ggagactgat ttgctccgct tccttttgta
    28261 aatccatgga agctagaaac tggagaatca tagtaccacc gtcttgcgtt ttcacctcgc
    28321 gctcctcaat aaagagagag gttgtctggc ggtctgtgtc cagaggaaga ctgtccttga
    28381 cttctaactt gtcctcggtc atctcacctt tgacggtccc cttgatatca ctagtctggg
    28441 aatacaagtc taacacttgc tcgatactct gcctatcttt cccttctagg gactgggcaa
    28501 tggctgttgc cttttgacca atggtttcct gacgatgact cagataagtc gaaggaaaaa
    28561 gaaaataaat agctaaatga aggcagataa ccagaacact aaatatcgag aaggtataga
    28621 taaatatctt tgcaaataaa cctgttcgtt tcattttcgc tccaatttat aaccaacatt
    28681 gcgcacagtg aggatacaat ccaagtctag ctttttccgc aattccttga tataaacatc
    28741 aataacacgg tcaaagggaa cctcatctgt cgctttccag acggcatcga taatctgaga
    28801 ccgagtcaag gcccggcctt catttttcac tagatagtcc agaatttcca actctttggc
    28861 attgataggc acttcttgac ctgcgaggct tgcactgtag ctttcaaagt ccaccttggt
    28921 atccttgtaa gaaaagattc gtcctgtatc gtagtagcgc ttgaaaatcg cgtccaccct
    28981 cacttttaag agggagagag agaaaggttt ttccagatag ccatctgcca aagaggcaaa
    29041 ggcactcatc ttgtattcct catcctgaaa agctgtcaac atcaagacag gaacctgact
    29101 ggttttacga atctcagcta ggacttctaa gccgttaagc ttgggcatct ggatatccag
    29161 taaaaccagg gccacctcat agctagaaaa ttgctccaga gcttcctgac cgtccgctgc
    29221 ctcaatagtt tcatagccac aatccgtcaa ataatcactg accccctcac ggatcatctc
    29281 ttcatcttct acaattaaaa ttttcatact ttaactgctc tctatttttt atttttctta
    29341 gaataaatac ctactctatt ttctattata gtctcttgct ggccttttgt ctgtaagtaa
    29401 ctgaccacta gataaaacgt tgtgaaattc ctttctcata aattccataa ctttagtata
    29461 ttatatttaa gcactaaagt acaaagaaag caactgaaag caatgatttt caccactgct
    29521 ttcagattta ttttgaattg ttaaatagcc attcctatcc actattcttg aatagaaaca
    29581 caagatgcaa tctttattcc agactcattt tttcaaattt attcaccatc cagcaagagt
    29641 tcttttggtt gttttctaag gagattgctt gaagcaagcg ccataacgag aaccactaga
    29701 accaaggcaa ggacaaaaat gatgataaag tctgatgtct gaatggaaat gtctaggctc
    29761 gacaaggtct tgctaaagcc atctacttct gcaccaccac caaggttaga ggcttgagcc
    29821 gccttactag cctgtttggc aacacctgaa gtcacattgg caaggacagt gtttccaatt
    29881 gcacgggcag tgtaattagc taggaagtaa gcagaaacta gagcagggat agcaatcaag
    29941 atagattcgg tgatgaattg acccaagata cttgcctgct tgaggccgat agagaggaga
    30001 attcccactt ccttgcgacg ggcgttgatc caaaggctga gcaagagggc aaggaggaga
    30061 actgagaagc tcaagctacc ccagaagagg aggttggcca tcttgtacat accagagata
    30121 gattgctcaa gagctgggta gttagaggag ctcttgacga gtgtgtagct cttccagttg
    30181 ataccactga tgccattcaa ctctttcata acatcatcca agttcttgtc tgctgttaca
    30241 aagaaggttg cgtccccata aatggctgtg tcttctgtgt atccataaag ttttgcagca
    30301 gtgtgaatgt ctgtaatagc tgtgttttcg taaagttctt gtgagtaggt tactgctgac
    30361 ttattatgac catcaaagag tcccttgatt gtcacttcaa ctgtttcctt ggctcctttt
    30421 tcattatctg catcgtagat attagagtcc agtttaacct tgtcccctac tttccagccg
    30481 tgtttggctg ccaagtcctt gtgcaagagg attttatcct tgtcgtcgtt ggttaagtgc
    30541 tctccttcga ctagtttata agaaccagag acaaacttgt cttctttaga ggagtcattg
    30601 acacctgtaa tcatcaagct acttccaaaa cgtttggcac gatcagcagt gagattcttc
    30661 ttggtttctg gcgtttcaat caggtcatat ccagtcaaat ctccgatagc gttgatacgt
    30721 ttgacataag actcgatggc cttgttttcg gtgatttttt tgatgtcttc acccttgata
    30781 ttcccagcac cacgaggcgt tccttggttg acgcgacgat tgatttgcat ggagaagcta
    30841 ttggtgatat ttttaaaggt ctcctgagaa gccttggcag tagctccctt gattgacaag
    30901 ccgaccaaac tcaagctcgc catgaggaga ataatcagga aaatgacaat cgatttgaaa
    30961 aacttccttg taacataggc aaatgcgttg tgtaacatag attccctttc tagattttgt
    31021 tttaatcatt ctatcaaaat aagctcaaat tatttactag tattgcgcgt ttcagtcagt
    31081 ttcttatcct ttaattcaag tgtaatatct gacgcttgtg ccacttcttt actgtgagtt
    31141 acgacaatca cacatttacc tgttttctgg gcaagtgatt tgagtagttc gacaatatct
    31201 ccagcagttt taggatccag atttcctgtt ggctcatcag ctagaataac tggagcttct
    31261 gagaccaaac tgcgagcaat ggcaacacgt tgctgttgac cacctgataa ctggagaaca
    31321 ttccgcttga tctggctttc atccaaacca agctcaagaa gtgtattctt gcttgccttt
    31381 ttgttgacca atcggatatt ttccagcgga gaaagataat ctatcaagtt ataattttga
    31441 aagaccaggg aaatatggtg catgcgatgg taagaatagc ccttcttacg aatatcctct
    31501 ccttgaaaaa ggatagaacc ttcaacagga ctatctagac cagcaagtag ggacaagagt
    31561 gtggattttc ctgctcctga ctccccaata atactgtaaa attttccagg ttcaaaatta
    31621 taatcgatct gatataggac tgcttcagca gtattcttat aacggtaggt aacatcttgt
    31681 aattgtaata aagtcatgat ttctccttct taactaatag atgataaaat ttctttcggt
    31741 gattttctaa ataagaatag gaaacaaagg gctacagata agcaactaag cagaactaga
    31801 aaaacatagg attctgcaaa agataagatg ctagttgata aactgcttgc tttggctagt
    31861 gtatcttgta agcttgcctg atctccactt gctagtagag tttggagtag gtaagttgtg
    31921 attccgtttc ctgcaacaaa tgctggaagc aaagctccaa gagataccaa aactacctct
    31981 aaacagaatt gtaggaagat cgagctcttg ccttttccaa gtgcaagtaa aatccccact
    32041 tcatagaccc gttctctcaa ccagagagac aaaaccagaa ttaaggctcc agctcctgct
    32101 atcaacatcc cataaaggaa gatggtcagg aaggtttgga aagttgcaac tgagtctttg
    32161 atttgttcaa aagccttgtt ttccttttcg acttggtagc cttgattttc caaggccaag
    32221 ttttctacct gcttcatgag tccgtccatt tccttaggat tttctacata gaagcgtgct
    32281 gcactgactt gagcttcact attgcccaaa agggtttggc tactttcata gtctgtaaag
    32341 acttgatttt cactgaagtc agaagacaag cctgtgaatt tctcttgttt tttaccagaa
    32401 aagatgccaa taatctcaaa ctctactgtt tgtccttttc cagattcaga ctgaccagca
    32461 tccaagccaa tcttgtcatg aagtgaaaga ccgttcttct tagccaattc ttcgtggata
    32521 aggattttct tggaatcccc tttttgaagg tgtcgccctt cttttagatt gaaagccgaa
    32581 ctggtaaagg ttacatcctt ggatgaatcc tcaagagccg ttaagctaac caagttattg
    32641 tctgcagctg ataaatcatc acgctccacg ctctgctctc cagtcactgc ttccttgtct
    32701 tttagttttg cgaccgtctc aagttcagga gagacatttt ccagcccctt aatcttgctt
    32761 acagatgcta ggtctgacaa cttgaatgtc tgaccattct ctatcttctt aatagaaaaa
    32821 gatgtattga gtgatttata aagattgctt tctactgttt tgttggactt catcagagtc
    32881 aaacaggctg aaattccggc caataagacc aataaaatca gaaataaaat aaaacttctc
    32941 agtcgctttc tgctgacata agcccaagat ctttggattg gattcatttg tcacctccat
    33001 atttgtaaga ctattataaa acccaaatat gaaatgttta tgaaatacga aaaaaaaata
    33061 tcgagtaggg gataatctct agcccctctc acaccaccgt acgtgccgtt cggcatacgg
    33121 ctgttcaact aacttttaac gcatgtcgtt ca
//
LOCUS       DAVMCG010000020        32278 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVMCG010000020 DAVMCG010000000
VERSION     DAVMCG010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.020"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..998)
                     /gene="phtB"
                     /locus_tag="VYP66_001139"
     CDS             complement(<1..998)
                     /gene="phtB"
                     /locus_tag="VYP66_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEV1850699.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKR"
     gene            complement(1156..3606)
                     /gene="phtA"
                     /locus_tag="VYP66_001140"
     CDS             complement(1156..3606)
                     /gene="phtA"
                     /locus_tag="VYP66_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1850700.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQTSQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3859..5592)
                     /gene="ptsP"
                     /locus_tag="VYP66_001141"
     CDS             complement(3859..5592)
                     /gene="ptsP"
                     /locus_tag="VYP66_001141"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1850701.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(5598..5861)
                     /locus_tag="VYP66_001142"
     CDS             complement(5598..5861)
                     /locus_tag="VYP66_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1850702.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            6212..6430
                     /gene="nrdH"
                     /locus_tag="VYP66_001143"
     CDS             6212..6430
                     /gene="nrdH"
                     /locus_tag="VYP66_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1850703.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            6511..8670
                     /gene="nrdE"
                     /locus_tag="VYP66_001144"
     CDS             6511..8670
                     /gene="nrdE"
                     /locus_tag="VYP66_001144"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1850704.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            8858..9820
                     /gene="nrdF"
                     /locus_tag="VYP66_001145"
     CDS             8858..9820
                     /gene="nrdF"
                     /locus_tag="VYP66_001145"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1850705.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            10002..10763
                     /locus_tag="VYP66_001146"
     CDS             10002..10763
                     /locus_tag="VYP66_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1850706.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10962..11126)
                     /locus_tag="VYP66_001147"
     CDS             complement(10962..11126)
                     /locus_tag="VYP66_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1850707.1"
                     /translation="MESLGKWYVSTGKEWICHSDDELEEFKNLFLNFINPEEWDTISF
                     DSDFMPFQQS"
     gene            complement(11261..12667)
                     /gene="lacG"
                     /locus_tag="VYP66_001148"
     CDS             complement(11261..12667)
                     /gene="lacG"
                     /locus_tag="VYP66_001148"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1850708.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDHKNPADVRAAELEDIIHNKFILDATYLGHYSEKTLAGVEAILAANGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            complement(12882..14573)
                     /locus_tag="VYP66_001149"
     CDS             complement(12882..14573)
                     /locus_tag="VYP66_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1850709.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARYFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FNLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            complement(14573..14890)
                     /locus_tag="VYP66_001150"
     CDS             complement(14573..14890)
                     /locus_tag="VYP66_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1850710.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            complement(14926..15762)
                     /locus_tag="VYP66_001151"
     CDS             complement(14926..15762)
                     /locus_tag="VYP66_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1850711.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            complement(15996..16976)
                     /gene="lacD"
                     /locus_tag="VYP66_001152"
     CDS             complement(15996..16976)
                     /gene="lacD"
                     /locus_tag="VYP66_001152"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1850712.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            complement(16978..17907)
                     /locus_tag="VYP66_001153"
     CDS             complement(16978..17907)
                     /locus_tag="VYP66_001153"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1850713.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQDPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            complement(17918..18433)
                     /gene="lacB"
                     /locus_tag="VYP66_001154"
     CDS             complement(17918..18433)
                     /gene="lacB"
                     /locus_tag="VYP66_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1850714.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHHESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            complement(18464..18889)
                     /gene="lacA"
                     /locus_tag="VYP66_001155"
     CDS             complement(18464..18889)
                     /gene="lacA"
                     /locus_tag="VYP66_001155"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1850715.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            complement(19046..19522)
                     /locus_tag="VYP66_001156"
     CDS             complement(19046..19522)
                     /locus_tag="VYP66_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1850716.1"
                     /translation="MPYFIGGHPGFNCPLLDDGVYEDYYLESEKEETCSVPRPFPETG
                     MLDFQDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFP
                     NLIIWSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            complement(19559..20362)
                     /locus_tag="VYP66_001157"
                     /pseudo
     CDS             complement(19559..20362)
                     /locus_tag="VYP66_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(20370..20672)
                     /locus_tag="VYP66_001158"
     CDS             complement(20370..20672)
                     /locus_tag="VYP66_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1850717.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIILPAKQNMV"
     gene            complement(20710..21186)
                     /locus_tag="VYP66_001159"
     CDS             complement(20710..21186)
                     /locus_tag="VYP66_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1850718.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGYLEDLSKISEPEKLYAYIAEATA"
     gene            21360..21440
                     /locus_tag="VYP66_001160"
                     /pseudo
     CDS             21360..21440
                     /locus_tag="VYP66_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21689..23512)
                     /gene="lepA"
                     /locus_tag="VYP66_001161"
     CDS             complement(21689..23512)
                     /gene="lepA"
                     /locus_tag="VYP66_001161"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1850719.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(23591..24319)
                     /locus_tag="VYP66_001162"
     CDS             complement(23591..24319)
                     /locus_tag="VYP66_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1850720.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            complement(24321..25988)
                     /gene="recN"
                     /locus_tag="VYP66_001163"
     CDS             complement(24321..25988)
                     /gene="recN"
                     /locus_tag="VYP66_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1850721.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLESIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            complement(25995..26426)
                     /locus_tag="VYP66_001164"
     CDS             complement(25995..26426)
                     /locus_tag="VYP66_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1850722.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            complement(26419..27234)
                     /locus_tag="VYP66_001165"
     CDS             complement(26419..27234)
                     /locus_tag="VYP66_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1850723.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            complement(27227..28102)
                     /locus_tag="VYP66_001166"
     CDS             complement(27227..28102)
                     /locus_tag="VYP66_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1850724.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLQSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            complement(28099..28311)
                     /locus_tag="VYP66_001167"
     CDS             complement(28099..28311)
                     /locus_tag="VYP66_001167"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1850725.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            complement(28289..29629)
                     /locus_tag="VYP66_001168"
     CDS             complement(28289..29629)
                     /locus_tag="VYP66_001168"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1850726.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEDLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVENLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            complement(29757..30395)
                     /gene="udk"
                     /locus_tag="VYP66_001169"
     CDS             complement(29757..30395)
                     /gene="udk"
                     /locus_tag="VYP66_001169"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1850727.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            complement(30503..30805)
                     /locus_tag="VYP66_001170"
     CDS             complement(30503..30805)
                     /locus_tag="VYP66_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1850728.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            complement(31046..31924)
                     /gene="truB"
                     /locus_tag="VYP66_001171"
     CDS             complement(31046..31924)
                     /gene="truB"
                     /locus_tag="VYP66_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1850729.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
BASE COUNT         9351 a         7039 c         5852 g        10036 t
ORIGIN      
        1 attcgttttt ccaattcaga catttgttca taagggataa agtggtaatg gttaccatga
       61 gggacagcta cacctctggc ggttcgactt gtgatttgcg ctgggtcgaa aataaggcca
      121 tcagattcca catggcgttc tgataagggt ttagcataca attcacgtaa aaggcttgaa
      181 atgttttccc cttgattttg atgataagtt ggagtgacag tcagattgtg gttctctgac
      241 aatcttggtt gagctggatt tgcattataa ctagaacttg aagaaggacg agatccctgc
      301 ttcccattcc aataggcttg ggcagcagct aactcgctag ctgataactc attcttagga
      361 atgtaatggt aatggtcgcc gtgaggaacg atataagcat cacccgtgtc ctcaatgata
      421 tcagatgcat tgaagatata cccatcatcc gttgtataac gtccttgggc tctggctgca
      481 gcaacagcat tatctgctct tgagttatga ttatgactgc gttcctgctt ctgacgttta
      541 atctcttctt ttgtccgaat attatccgca tgagctgcat ccttaaggta aacatagtat
      601 ttaccgttta ccttaatgac ataaccaccc ttgatttcat tgacaatgtc tgaatccttc
      661 aactgataat tcggatcttt catgaggagc tcttcactga tgatggcatc ataaggaacc
      721 ttgccattat agtaatgata atggtctcca tgagaggtca cataaccttg atccgtaatc
      781 ttgataacaa tttgttcggc gttgatcccc tccctcttac tgacttcatc tggtgtcaag
      841 ttttctgcct tttgaccagc ctgatcacca tctatataag caactcgatt agactctttc
      901 ttatcctgac cagcttggta acgtccaagc tcataggaac aaacacttag ggcaaggact
      961 gccactgaac ctgctagata ttttttattg attttcattc tttcctcttt tcttaagtat
     1021 atttgattca ctataaagta ataaaccggt taattaacta gttaatagtt tactcttttt
     1081 aatattgctt gtcaagaatt ttacatatat acataataaa aatgaaagcc tctttatcga
     1141 gactttcatt tttcattagt ttattttttc cttacttaca gatgaaggat tacttccttt
     1201 taacaacgca agtaattttt ctgcttctgc catgatacta ttgttatcca taatttgaag
     1261 agtcaaatta tttcgtaaac cagctagagt ttctgttgca ttggctttca gactagaatc
     1321 cgttactttc gcaagcaaaa cttctgcttc tttgagttgg gcttctactt tttcagtctc
     1381 tacttgaggg acttctggct cagcaggtgt ttcctctact ggctcttcat ccgctttgaa
     1441 gttcttattt ggatcttcac tgtggtcttt cttgcctaac acatgctcac tggcattgcc
     1501 ccatccatca ttagaatgtg gacgttcgtc agggtgttct acgtagtact taatcgtcgc
     1561 aaacaaatct tccaaggtat agccatttgg agctttgtat gtgtgatcat caaaccaagc
     1621 aaatttaatg ttatggtaat gatccttatg aggaataatc aaattaccgt ttttaacctc
     1681 aactgtatgc tcaaccatat atggaagtcg aacgagtgga attcgttttt cccctttcac
     1741 acgattgtaa atagctgctg cactatctcc agttggattt gctttaacat ctgcgtctgg
     1801 agatggaggt aggatacctt tttctttagt ataggcttga gctgcaactt tttccttatc
     1861 agaaaggctg tcttttccaa tccagtgact atggcccata tgaggcgtta catatgcatc
     1921 tccttcatca ctgattatat catgttcatc aaaaatataa ccatctgacg ttgtatactt
     1981 atcagctaat tgagcaatac gaacttcgtc ttcagtatac tcaatttgag aatttggctt
     2041 gccaagtcgc tctggatggg taattggtgc taggaatgcc aataaatcat ctaccaattt
     2101 ttctttatta gtcgattcat cattcaagcg ttctaataat ttgtctaagg cttggaaatc
     2161 agaattacga cccttatttt caaacaaggc tttatgagcc tcagttaaca gattatatgc
     2221 tttatcataa aattcttggt cacgaggagc aacattttct tttttagcag ttaaagtgtg
     2281 tgaaacactc tcttgttttg ataacttgct ttcaagattt ttaacagttt cagatggtaa
     2341 atctttcgca aagacataac gagagatgcc cttttcttcg aatacatatc cttccccaac
     2401 ttttcgtacc agctgactaa ccaaagaaga atttgagtct attttaagat ttggtgcagg
     2461 ttgcgggcct ggactaggtt ccggagtcgg ttgtggactt ggttgttctg gccttgaatc
     2521 tggtacccaa tggtttgaac gataacgaag gggaataata cgagcgattc gttcttccaa
     2581 ttcagacatt tgagagtaag ggatgaagtg gtaatgatct ccgtgtggca ctgcaacacc
     2641 tctagctgtt cgacttgtga tttgcgctgg gtcgaaaaca aggccatcag attctacatg
     2701 tcgttgactc aaaggcagtt tgtagagctg tttcaagaga ctatcaatgt cattactttg
     2761 acttgtttga ctgttagtgt tgctgttgtt gcttgtgtta gtatttgtag ttcctggatt
     2821 gcttacagaa ggtacccagt ttgttcttga agtgttatcg ctattttgtc ggcgataggt
     2881 tcttgaattt gacagatttc cccgaccaga taggaaggct tctgcagcag ccaactcgct
     2941 agctgataac tcattcttag gaatgtaatg gtaatgatct ccatgaggaa cgatataagc
     3001 atcaccagta tcctctatga tatcagaagc attaaagata taaccatcat ctgtagtata
     3061 gcgtccttgc gaacgtgcca aggcaacagc accatcgttt cttggagtcc caccttcacg
     3121 atgttgacta tgttcttgtt tttgtcgatt gatttcctct tttgtacgga cgttatccgc
     3181 gtgggcagca tccttaaggt aaacatagta ttttccatct accttgataa catatccacc
     3241 cttgacctca ttaacaatat cctcatcttt tagcttatag ttcggatctt tcatgagtaa
     3301 ttcttcactg aaaatcgcat cataaggaac cttaccattg taataatgat agtggtcgcc
     3361 atgtgaagtg acatagcctt ggtctgttat cttgatgacg atttgctcag cattgattcc
     3421 ttcacgcttg ctaacctcat caggagtcaa attctccgtt ttttgcgtcg cttgttttcc
     3481 atctatatag gaaacacgat tattttcctt aaccgttcta gcttgataca gtcccaactc
     3541 gtaagaacaa acacttaaaa tcaaagctgc cgcagaacca acaaggtatt tcttattaat
     3601 tttcatcgaa actctctttc tatttgatat ttctagttgc aattcatttc taaattgcag
     3661 aaactcctct ctattactta actggttaat agtttactcc taaatctcca acttgtcaag
     3721 aattttatga accatttaag tattttttgt tctgactact actttttcaa gaaaatcttt
     3781 ctataagaaa gattttcttg aaaattcttt ttaaaatatc aaaaaaatcc ctgtaactga
     3841 gttgcaggga cttttcgatt aatcaaaatt aacgtattct ttttgaagtt caagaacttc
     3901 ttccattgtt gagcattctg taagggcacg gtttgcgtac tcttccatct tagctgtgtc
     3961 gagtttcttc atcaagctgc gtgtacgaag tacagatgtt gctgacatag agaactcatc
     4021 caagcccatt ccgacaagaa gtggaacagc ttgttggtca ccagccatct caccacacat
     4081 accagcccat ttaccttcag cgtgagctgc tttgatcaca ttgttaatca agcgtaggat
     4141 tgatgggttg tatggttggt aaaggtatga aacttgttcg ttcatacggt ctgctgccat
     4201 tgtatattgg atcaagtcgt ttgtaccaat tgagaagaag tcaacttctt tagcaaattg
     4261 gtctgcaagc atagccgctg caggaatctc gatcatgata ccaacttgga tgttatccgc
     4321 aactgcaaca ccttcagcaa gaaggtttgc tttttcttca tcaaagactg ctttcgctgc
     4381 acggaattct ttcaagagcg caaccattgg gaacatgata cgcaattgac cgtgaacaga
     4441 cgcacgaaga agagcacgga tttgtgtgcg gaacatagca tctccagtct cagagataga
     4501 gatacgaaga gcacggaatc caaggaatgg gttcatttcg tgaggcatat cgaagtaagg
     4561 aagttcctta tctccaccga tatccattgt acgaacgaca acaggtttac cgttcattcc
     4621 ttcaagaaca gccttgtatg cttcatactg ctcatcttca gttgggaagt cttgagaatc
     4681 catgtacaag aactctgtac ggtaaagtcc aacagcttct gcaccgttgt tgttaacacc
     4741 ttcaacgtct tttggagtac cgatattagc agccaactcg aagtgtttac cgtcagcagt
     4801 cactgtttga gcatctttca agagcgccca ttcagctttt tgtttcgcat aagcttcacc
     4861 agctgcttta aattctgccg cttgttcatc agttgggttg ataataacct caccagtgat
     4921 cccgttaaca gcaaggatgt caccgtcttt aacgatttca gtgatgttgt ttgtacctaa
     4981 tacagctgca atttcaagtg tacgtgccat gatagctgag tggcttgtac gtccaccgat
     5041 gttggttaca aaagctttta caaagttttt gtccaattga gctgtatcag atggtgtcaa
     5101 gtcatgtgca atcacaatca cttcttcatt gatagaagct gggtttggca attttttacc
     5161 aagaaggttt gccaatacac gttttgtcac atcgcggata tccgctgcgc gttcttgcat
     5221 gtatgggttg tcttccatgc cttcaaagat agtgataaac atatctgtaa cttctttcag
     5281 acctgcttct gcattcactt tcttcgcacg gatagtttcc ttgatttggc tgatcatttc
     5341 tgggtcagca agaaccatta agtgagcatc aaaaacttga gctgcttctt caccgagcgt
     5401 acctactgct ttctcgcgaa taacagaaag ctcgtcttgt gatgcctgta gagcggcatc
     5461 aaggcgagct tcttctgcgt ttgtatcttc gactgtaata gtctcaaatg acaaatccgg
     5521 ctgaacgagt agatatgctt ttgcaactgc aacaccgtca gatgctgcga ttcctttaag
     5581 catttctgtc atttccctta tgccaatcct tctttttcca ttgtttctga gattgcagcg
     5641 atagcgtcat ctgcatctgc accttcagct gagatagtta cgtcagcacc ttggccaaca
     5701 ccaagactca taacacccat aattgattta aggttaactg atttaccttt gtactcaaga
     5761 gtgatatctg aagcaaattt gctagcagtt tgtaccaaca atgttgctgg acgtgcgtga
     5821 atacctgttt ctgccactac gtggaaatct ttagaagcca tagtttgact ctccttttgt
     5881 tctttctttt tttgagttat atgtgataac ccttacaatt tagtattata ccatcttcta
     5941 ggattttttt caagcatttt ctggattttc cttcaatttc ctttcagata acttgctgaa
     6001 aatcttctat cctagataac aaaacacagg atatagtttc tttaaaaaca atttatagga
     6061 taatcattgc tatttcacaa tacaaacact atatattgtg tttatatata aaaacaacaa
     6121 aagaacacca ctatatttag ttcaaatcat tgacaaaatt ttattttctg atatactaag
     6181 atagtattaa attttgaaga ggagttacac aatggtaacc gtttattcta aaaacaattg
     6241 tgtccaatgt aaaatgacca agcgtttctt ggacagtaat aatgtctctt atcgtgaaat
     6301 caatcttgat gagcaacctg agtacgtcga tcaagttaaa gagctcggtt ttagcgcagc
     6361 tcctgttatc caaacaccaa ctgaagtctt ttcaggtttc caaccaggaa aactgaaaca
     6421 attagcataa tcttagtaca tcatccagaa gaaactgctt ttagggctaa cttagaagcc
     6481 tttcttttgt aattagataa gggaaatttt atgggattaa aacatcttga agacgtgact
     6541 tacttccgtc ttaataacga aattaaccgt cctgttaatg gacaaatcat gcttcataaa
     6601 gataaggaag ccttggatgc tttctttaaa gaaaatgtag ttccaaacac tatggttttt
     6661 gattcaatca aagacaaaat caattacctc attgaacaca actacatcga aacagccttt
     6721 atcaagaaat accgtccaga gttcttggaa gaattggctc aatttatcaa agaccaaaac
     6781 ttccaattca agtcattcat ggcagcttat aaattttaca atcaatatgc cttaaagact
     6841 aatgacggtg aatactatct tgaaaatatg gaagaccgtg tcttcttcaa cgccctttat
     6901 ttcgctgatg ggaatgaagc tgttgcaatc gatattgcca atgaaatcat ccaccaacgc
     6961 taccaacctg ctactccttc cttcttgaat gctggacgtg ctcgtcgtgg ggagttggta
     7021 tcttgtttcc taatccaagt gacggatgat atgaactcta tcggacgttc tatcaactca
     7081 gctcttcaac tttcacgtat tggtggtggt gtgggaatta ccctcagcaa ccttcgtgaa
     7141 gctggtgcac ctatcaaagg ctatgaagga gctgcttcag gtgtcgttcc tgttatgaag
     7201 ctttttgaag acagcttctc ttactccaac caattggggc aacgtcaagg tgctggtgtt
     7261 gtctacctca acgtctttca cccagatatc atcgctttcc tttcaactaa gaaagaaaac
     7321 gctgatgaaa aagtacgtgt caagactcta tcacttggtg ttgtagtacc tgataaattc
     7381 tacgaattgg ctcgtaaaaa tgaagaaatg tacctcttca gcccttactc tgtagaaaaa
     7441 gaatacggtg tgccattcaa ttacatcgac attactgaaa aatacgatga attggtcgca
     7501 aatccaaata ttcgcaagac aaaaatcaag gcgcgggatt tggaaactga aatctctaaa
     7561 ttgcaacaag agtctggcta tccttatgta gtcaacatcg atacggctaa ccgtgcaaat
     7621 cctgttgatg gaaagattat catgagtaac ttgtgttctg agattcttca agttcaagaa
     7681 ccaagcttga tcaacgatgc tcaagaattc cttcaaatgg gaacagatgt ttcatgtaat
     7741 ctgggttcaa ccaacgtggt taacatgatg acttcacctg attttggtcg ttctatccgt
     7801 gctatggttc gtgcccttac tttcgttaca gatagttcac atatcgtagc tgtaccaacg
     7861 attgaccatg gaaatagcca agcccacacc tttggtctcg gtgccatggg actgcacagc
     7921 taccttgccc aacaactcat tgaatatggt tcacctgagt ctgttgaatt tacaagcatc
     7981 tactttatgc ttatgaacta ctggaccttg gtagagtcaa acaatattgc gcgtgaacgt
     8041 ggtattacct tccacaactt tgaaaaatca gactatgcta acggaagtta ctttgacaag
     8101 tatgtaactg gtgaatttgt tccaacatca gaccgtgtta aagaactctt caaaaatgtt
     8161 tttatccctg gtgttgctga ttgggctgaa cttcgcgaca aggttcaaga agatggtctt
     8221 taccaccaaa atcgccttgc tgtagcgcca aatggttcta tcagctatat caacgacgtt
     8281 tctgcttcta tccacccgat tacgcaacgt atcgaagaac gccaagagaa gaaaattggt
     8341 aaaatctact accctgctgc tggcttgtct acagaaacca ttccttacta cacttctgcc
     8401 tacgatatgg atatgcgtaa agtcatcgat gtttacgctg ctgcgactga acacgtggat
     8461 caaggacttt cactcaccct cttcatgcgc agtgacattc caaaaggcct ttacgaatgg
     8521 aagagggaaa ataaacaaac gacacgtgac ttgtctatcc ttcgtaacta tgcctttaac
     8581 aagggaatca agtctatcta ctacgtccgt acctttacag atgacggtgg agaagtcggc
     8641 gccaaccaat gtgaaagctg tgtgatttag tttctagcat agaaacatta tttttcccta
     8701 agcagcactg ataaaatcaa atctactatg tcataacata atttatgtaa cattttaaaa
     8761 gtcggacttc cgactttttg tgcgatactc ctatagaatt atggtaaagt agaaataatt
     8821 gtgagttcgc aatactaaac acagaaagag attttaaatg gaaacttact acaaagccat
     8881 taactggaat gccatcgaag atgtcatcga caaatcaact tgggaaaaac tgacggagca
     8941 attttggctc gatacacgta ttcccttatc aaacgacttg gatgactgga gaaagctatc
     9001 taacaaagag aaagacttgg tcggaaaagt ttttggtggt ttaacccttc ttgacactat
     9061 gcaatctgaa actggggttc aagcccttcg cgcagacatc cgtacaccac atgaggaagc
     9121 tgttttcaat aacatccaat ttatggaatc tgtccacgct aaatcttact catcaatctt
     9181 ttctaccttg aatactaagg ctgagattga agaaattttc gaatggacca ataccaatcc
     9241 ttacctacaa aagaaggctg agattgtcaa cgaaatctac ctaaacggca gcccacttga
     9301 aaagaaagtt gccagcgtct tcctcgaaac cttcctcttc tactctggtt tcttcactcc
     9361 cctctactat ctcggtaaca acaaactagc caacgttgca gaaatcatta aattgattat
     9421 tcgtgacgag tctgttcacg gaacctacat tggttacaaa ttccaacttg gtttcaatga
     9481 attgcctgaa gaagagcaag aaaaactcaa agaatggatg tacgacctac tctatactct
     9541 ttatgaaaat gaagaaggct acacagagag tctttatgac ggtgttggtt ggactgaaga
     9601 ggttaaaacc ttccttcgct acaatgccaa taaagctctc atgaacatgg gacaagatcc
     9661 acttttccca gattcagctg aagatgtcaa cccaatcgtt atgaacggta tttcaacagg
     9721 aacttccaac catgacttct tctctcaagt cggaaatggt taccttcttg gcgaagttga
     9781 agccatgcaa gacgatgact ataactacgg tttagactaa ttctccatca ctctcaatca
     9841 tcaaaaagta aactagaaac atcaaagtta taacccaaca aaaatatcga aagttttgaa
     9901 aacaaacttc gatatttttg tttttgtttc attttgttgt ttttgtattt gaatgatgag
     9961 tttgtttatg gtaagatagt agtaggaaac gaggtgataa tatgctcaaa caagaaaaat
    10021 tagccaaaat tttagagata gtaaatagta aaggaaccat aacggttaaa cagattatgg
    10081 acgaaatagc cgtttcagat atgactgcaa ggcgctattt acaggaatta gctgataaag
    10141 atttgctgat tcgtgtgcat ggtggagctg aaaaacttcg aaccaactcc cttttgacta
    10201 atgagcgatc aaatattgaa aaacaagccc tccaaacggc agaaaaacaa gaaatagccc
    10261 attttgcagg cagtctagta gaagaaagag aaactatttt cattggacca ggaacaacat
    10321 tagagttttt tgcgcgtgag ttgcctattg acaatatccg cgtcgtaacc aacagtctac
    10381 ctgtttttct gattttaagc gaacgaaaat taacagattt gattttaata ggtggaaatt
    10441 atcgcgatat tacaggtgct tttgttggca cattgaccct acaaaatctc tctaatctcc
    10501 aattttctaa agctttcgtt agctgtaatg gtattcaaaa cggagctcta gctactttta
    10561 gcgaggaaga gggagaggct caacgcatcg ctttaaataa ttctaataaa aaatatttac
    10621 tcgcagatca tagtaagttc aataagtttg atttttatac tttttataat atatcaaatc
    10681 ttgatactat tgtttcagat tctaaactaa gtgattcaat cctttttaag ctatctaaac
    10741 acattaaagt catcaagcct taataaactg aaagagcctg ggtaacaact caatttcaga
    10801 agaaaaaaag taaatcttcc cacaataaaa agcatagtat caggtgtttc aacacctgat
    10861 actatgcttt tttctatgat tttcattgag tataagcaac gtgattagat aagagtttta
    10921 cagagtacta aatataagat ttaacttttt tgagaaattg gttacgattg ttgaaacggc
    10981 ataaaatctg aatcaaagga gatagtatcc cattcttcag gattgataaa atttaaaaat
    11041 agatttttaa attcttccag ctcatcatct gaatgacaaa tccattcttt accagtcgag
    11101 acataccatt ttccaagact ttcaattctt cactcgtcaa acacggtatt tgagagcatt
    11161 tttcgaaatt tataatataa actttttcat aaatagattg gataaaatct ttgaacatct
    11221 tttggactca ctaaaattct atatctaatg actaattcta ctagtctata atctgagttt
    11281 ccgctacttt cttgtaccag tgagctgatt tcttaggata acgttcttga gtttcaaaat
    11341 ctacgtagaa gagaccataa cgtttctcat aaccgtttga ccatgagaag acatccatta
    11401 atgaccaaat gaagtaacct tttacattag ctccatctgc aatcgcatca gataaaacct
    11461 ccaagtgttg cttcacgtaa tcaatacgtc catcatcgta aacagtgtta tcaacgaact
    11521 catctttata tccaagacca ttttcagtga tgtagatttt cttatagtta ggataatctt
    11581 tcttcacgcg catgatttgg tcatacaaac cttgagggta gataatccaa tcccaatccg
    11641 tgcgtggtac atagtcagga gctacacgac gaccaatacc tttgatttgg tatttagagc
    11701 ttcctttttc acctttacca ttatggataa tttcagtttc tccatcaaag gcttccatcc
    11761 agtcactcat atagtagttg attcctagga aatcattcaa gtcttttgca gcttctaatg
    11821 ctgtaaaatc ttcttcacga agatccaagc taccaccatt ggcagccaag atagcctcta
    11881 cccctgccag agtcttttca gagtagtgac ccagataggt tgcatccaaa ataaatttgt
    11941 tgtgaataat atcttccaac tcagctgcac gaacatctgc tggattttta tgatctagag
    12001 gatatttagt aggcagggcg tgaacaacac caatttcccc tttatagcct ttctctttgt
    12061 acaattttac cgcgcgtgca tgagacacca tcatattgtg gtgtgattga aagactttgg
    12121 caaggtcgta ctggatacct ggagggaatt tcccaaccaa atattgacca tcaccgattg
    12181 gtccaatttc attaaaggtt gtccaatagt ttacttctgg aaattcttca aaacagaaag
    12241 cagcgtagtc tacaaaatgt tcgatatttt cacggtttaa gaagtctcca tttgagtgga
    12301 gagcttctgg cgtgtcaaag tgatgaagag ttacaaaagg ctcaacatga cgtttgtgac
    12361 actctgcaaa taaattatga taaaactcaa cacctttagc atttacttgg ccgtaaccag
    12421 tcgggaaaat acgtgaccaa gcaatagaaa ttcgaatacc attgacacca tactcttctg
    12481 ctagcttgag gtcaactgga tatcgattgt aaaaatcact agctggttcg gcagtgtacc
    12541 agtagttatc ctcaagatat ttatcccaag caactggtcc ttttccatca gtatgtgtag
    12601 caccttctgc ttgataagca gctgttgcgc caccgaaaat aaagtctttt ggaagtgttt
    12661 ttgtcatttt tttcacctat ttcttgattt aaataaagta aaagtgagag gagaggagtc
    12721 agtgagccat gcttctccat ctcacttctt gtaccaagtc actgaattgt gacatgagga
    12781 ggtaaaaacg atatcttttt accgacgaat taataaggcg attaggaaat tcgccatagc
    12841 gatttccgta acgatgggag actgtttcac agttcctagc cttaatcgaa ttgctcttgt
    12901 acgaatgcta gggcaccttt tccatcacga gttaatttga tgtattgagc gccttctgtc
    12961 ttagcaagtt taataccgag cttatctgtt tctgccttca tatcttcaaa gtttgaagca
    13021 acttgagggg caaggataac tagattaaac tctggtaaca tttcacggtg agcaccatag
    13081 ccgcctgctg ctgctttcac agggacattg tattctgctg ctgccttatt caaagcattt
    13141 gcaaggagtc cacttgtacc tccaccagca cagagaacga ggacatttgt ttcttcagtg
    13201 atggtatttt gtgctgcatc gacacccgct ttttcaagaa tagcatccgc ttttgcagtg
    13261 ttgaagtttg cagcaacttt ttctttcaat tcatcattag acttacctga acgttcttct
    13321 tcaagaattt gttcatcata gactttaagg aatgggtaat aaataactac gtcaaccaca
    13381 attagaaggg cagcaagaat gaatgatagc acttggaagt tagttccaag aactagacct
    13441 agtggagctg gagttgtcca tggtagatta gcagtgaatg agttcattcc aagagtttca
    13501 ataaagaatt tgaaaatcca tacgtttgca attggagcaa agataaatgg aatgaagaag
    13561 attggattca aaacaagagg tgcaccaaac aagattggtt catttacacc gaagaaggta
    13621 ggaactactg aagcacgtcc gattgcacgg ttacgtttcg attttgtcaa ccacatgaac
    13681 ataaatggaa cgaccaatgt cgcacctgta ccacccatgg taacgataaa catttgtgta
    13741 ccagaagtaa gaatcttgtc tgcatgcatc ccttgttgga gaaggttcaa gttaacttcg
    13801 gcattggcat aggtaatagc tgcgatagct ggttcaacga tagatggacc atgaatccca
    13861 acaaaccaga agaaggcaaa ggcaccaaag ataatggtaa taccaaggta tccgtctgct
    13921 gctgagaaga gtggtgcgaa gaatttaccg attgattctg ccacactaga accaacaaaa
    13981 taacgtgcta ataagtcaag agcataaaga gaaacaacag atagagtgaa tggaatcaca
    14041 tctttaaaga cttgtgagat atttggtgga acttcgtcag gcatacgaat agtgacgttg
    14101 ttcttaacac aaaccttata gatggctaca gtaacaaagg cagcaaggaa ggctgaaagc
    14161 aaaccttttg tccccaagaa tccagtagct agaccacttt cgataggatc agctgccaac
    14221 atcaacaaac caacaatcgc tgctaacagc gttgacatat agttgatttg attggttttc
    14281 tccatgctac ggtttactga gtcggtcaat gacttagctg ttgtaccagc taccaagaga
    14341 gccagaatac ccatagaata gctataaggt ttcatcagaa aggctacaac ttcatcagac
    14401 catttaaagc cccatgagtt tggtacaaag gcaatcaaga taaagatact tgagaagaga
    14461 ataacaggca tacctgcaat gaaaccatca cgaatagcac gaagatagat attacgagat
    14521 agtttctcaa agaaaggctt tcctttctcg ataaatgcaa ttagtttgtt cattatttaa
    14581 ctcctctctt atagagttcg atcaaatggt gcatcaaatc ctttaacaag atagttgtca
    14641 tcaagtggtc ttggccatgc atcatggtca cactatacgc taagtcctca ccagaagctt
    14701 ccttagtcaa tagacttgtt tgcgcgtggt gagcctctgc aatacagcta ccagcttcct
    14761 ctaccagagc gtccgctttt tcaaaatcac cagcttcagc agccttcaag gcttccaata
    14821 gttttgaacg agcatcgcca gcataggcta cgatttcaaa acctaacaat gttacttctt
    14881 ctctattcat gatagaattc tccttatata gttttaaata aatttttatg acaataaacg
    14941 ttggatatgt agaactagat aaactcgttc acttttatac aaatcaagac ccgtatgttg
    15001 cgtaatcaca tcatagatct tggaaccaat ctcgaaggct tttggatagg attgtttaat
    15061 atgatcttcc atatccagaa gtgattggtt atcatctcta gatctgtcta aataatccaa
    15121 gaaataattc aaatggatca taaagcgatc atagaaatgg ttattctttt tagttcgttg
    15181 aattgcatag tccgttaaaa cttcttcaac attcctgaga atttctttcc tcttatcaat
    15241 cgactccaca agttccactt cattttcacc ttcagcatta atgaaatgat aagcaatccg
    15301 aataatttcg tcctcaggaa aatgatctgc tagcttctga cggtaaattt caaaagcttc
    15361 atttgcgatt tgaaaagcga caggatactt agcggaaata tctggcagat tactatcctt
    15421 gtaccttcct tgagttagag cttgataaga acagtaaata tgatctgtca aggttacata
    15481 gagatactct tgaatcggat aatgatattt ctttgatagc ttatcaatga tttcataggt
    15541 cactgtgata aaatcaagcg gaacatcttt gagaagagcc ataaagtttt ctctggactc
    15601 ttcggtcttc atccgaaaga ttttctcaac ctgattttca gcaatcaaat cccccttctt
    15661 ctttccgaat gcaattccct taccaattac aatcacctct tctcccttat catttctgac
    15721 aagcgagaca ttgtgattca ttggatttag aattcgatac atgtcaacct ccttttatat
    15781 cttaaaggta tataagtaca aaaaatgacc acaaatgaac tagaaaatca gctgatttct
    15841 aattcacctg tgatcatgcc taatattact tagtaacact caccttgtat taacttgtga
    15901 tttaagtata gcacaagtaa gttattttgt aaacctttac atacaacttt ttttaaattt
    15961 ttttagattc atgttcctaa actaggagga ctttcttaca cacgttcttt ccatgaagtc
    16021 gctgttgttt gaagaacttt attgagctca tcaatgtttt caaatccagt tgtgcgaagc
    16081 cattcgcgag ctgctgcttc accatctttg atgtaagctt caactgatcc tgcccatgta
    16141 gcacggccac aaagaactcc gttaaagttt gcacctgatt catgagcaaa tacaagagta
    16201 tcttggaaga gtttagctga tacaccagca ctcaagtaga tgtatggcaa gttcgttgct
    16261 tcatcttgcg ctttgaagaa ggctgctgct tcttcacgtg tataaactac ttcaccttca
    16321 gcgaagcctt caacatattt aatgttaaca ggaacttcaa ctttcaagac atcaatgtta
    16381 aagcgtgggt ctgaaaagac tttcatagcg ccgataactt tgtgtggttt tactttcgcg
    16441 tattctacag aacctgcatc cgcaattttt tcatcgtaag caaggatttc aaggaagaat
    16501 gggatatctt cagccacaca ctcagaaccg atgcgttcga tgtaggcttg tttttcttga
    16561 ttgagttcgt ctgagctatc tacatcatag taaagcaaga atttaactgc atctgcacct
    16621 tcttctttaa tacgttttgc agaccagaca tccaagcagt ctggcaagcg ttttgtgctt
    16681 gttgtgtcat aacctgtttt ttcataagca aggagaagac cagctttttc atcaagagct
    16741 ttagttgctg gaagtccata ctcagggtca agaagcatag atgaagcgta tttagtcaat
    16801 tcatctgcta ccaagacttt aagttcttcc atttgggcca cagttggttc ttctgtttgg
    16861 tgttgagcca tgaggcgttt caaagcacca cgttggtcaa atgcaagagc tgagatgata
    16921 ccattttcat cagaaagttt ttctaagcgt acacgttttt gttctgttaa agccatttta
    16981 tacctctttt actattaatt gatcatatag aacttgatag ttggccatgt tgacatgacc
    17041 agtcattttt tcttgagcat tgagcatacc aaggacattt gccttgatga gtaattctgc
    17101 atccgattct ttgtgaagaa gtcctgaaga aattcctgcc acagtagagt ctccagatcc
    17161 aacaggattt accacctgaa ttctaggaat atctaccttg tagaaagtgt caccatgttt
    17221 ggcaaaagta ccgttggcac caagtgaaac gataatccat tcaatccctg caaacaaagg
    17281 gtcttgaagt acttctttta attcatccaa atcctcagaa acttctcttc caagaagctg
    17341 agacaattct tcattatttg gtttgatgac tgttggttta tggggtgatt caagaacagc
    17401 ctgaagtgct gcacctgagc agtccaagac tacaggcttg ccagcttgat tagcaagttc
    17461 taccaagctc gcatagtaat caactggaag gccagctggc agactacctg agatggccac
    17521 tacttcaact gattccaaga gttttttgaa atgttccaaa aactcttgac cttcctgttc
    17581 caatacttca ggaccttttt caagaacttc tgtttggttg tctccgtgga gaatagcgat
    17641 acagttacga gtttctccct gaattgagaa gaaatctttc tttacttgat tatcgatatg
    17701 ttcaaccaaa aactcaccaa gtttgccacc cactaaacca gtagcaagaa cagaatcacc
    17761 aaattctgaa agtactcggg taacattgag tcccttacca ccagccgttt tggttacatc
    17821 caccacacga ttgacagtat caatcttcaa ctcatccaag ggataggaaa tatcaatgga
    17881 tgggttcatt gtaactgtta aaatcatagg ttacctctta gtcgtggtat tctccgcgat
    17941 cccatttttc aaggaattca gtgaagaagt ttgcgtctgt ttgttgagca ttgtgacttt
    18001 catggtgttc aattttcgca atcaattttt tgttttcttc agatggtttg tattcagcat
    18061 gaatgaaagc ttcgatgata tcacacataa gcaattcacc agtaatctta ccaccaaaac
    18121 cgataacgtt ggcgttcaat tgttctttag cataaagggc tgttgtcata tcacgaacca
    18181 aggcagaacg aacacctgga actttattta cagcgttgtt gataccaaca ccagtaccac
    18241 agatacatac cccgagatca gcttgaccac tagttactgc ttcccctact tttttaccaa
    18301 agattgggta gtgagtccgt gtatggtcat aggtaccaaa gtcaatgact tcatatcctt
    18361 ttgatttcaa aaattctgaa accgccattt tttcatcagt tacgatgtgg tcacatccaa
    18421 ttgcaattct catttttaac ttacctttct tactgtaatc taattagccc attttgttca
    18481 acatgtcaac ccggatttga tgacgtccac cgtcgtattt accattaaca aatcctttag
    18541 cgatgttttt agccaattca tcaccaacaa gttgtgcccc catagtgatc atacgtgagt
    18601 tgttgtggcc acgagtcata taagctgaac gttcgtcaga tacttctgca gcaaccattc
    18661 ctttgatctt agttgcaacc ataaatggac cagctccata agcatcaatc acgataccaa
    18721 ggttttgttc ttctttgttt acttctgcag caacagcgag agtcacatca acaaagtctt
    18781 gaccttcagc tgtaacatcc acaaggtgga agttttcttt ttctaagaag tctttcacaa
    18841 cttctttcaa tctcaaacct gcagcatctg caccgataac aatagacata ttgtatactc
    18901 ctttttattt tttctatgct ggattccagc agtgtattgg ctgtctttaa aaaacagtca
    18961 attagtcctc acaaacataa tatactacta ttgtttgaag aagtcaatag tttgtgtttg
    19021 tttttgttat ttatttttta cttttttata aaacttctat ctcaaaccct aattcttcaa
    19081 cctgattggc ttctaagaga caaacattct tcttatcttc taaatgatct ccttcttcaa
    19141 ggaatgttga caagccagac catggttcaa aggtaatgaa aggtcccttg ttcaaagttg
    19201 accagatgat gaggtttgga aattctgcaa aatgcacttt caatccctta tcatgtttaa
    19261 gagaacgaag ggcaattgtt cgagattgca attcatccaa agtcactgca tctgtgctga
    19321 aaagatcata actaagatct atttcttttt gtccctctag ccatggactt ctatcttgga
    19381 aatccaacat acctgtttct gggaaaggac gtggaacaga gcaagtctct tctttctcag
    19441 actctagata ataatcttca tagactccat catcaagtag aggacaatta aatcctggat
    19501 gtccaccaat aaagtaaggc atgaccttgc tagtttcttt attagacttc ctgcaaaact
    19561 agaatcctag ttcatgattg ataataccag cactcaaatt cattcgtaat ccgaagcgtt
    19621 tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt ttttactttg gcaaagatgt
    19681 tctcaacctt gcttctctcc ttagatagcg catggttata ggctttatct tcagctatta
    19741 gcgacttgag tttgctggat ttacgtggag tttgtacttg aggatatatc ttcatgagtc
    19801 cttgataacc actgtcagcc aagattttac cagcttgtcc gatatttctg caactcattt
    19861 tgaacaactt catatcatga caatagttca cagtgatatc caaagaaaca attctccctt
    19921 gacttgtgac aatcgcttga gccttcatag cgtggcattt ctttttacca gaatcattcg
    19981 ctaattcttt ttttaggtcg attgatttgt acttccgtcg catcaatcat taccgtgtcc
    20041 tcagagctga gaggagttct tgaaaccgta acaccacttt gaacaagagt tacttcaacc
    20101 cattggctcc gacggataaa gttgctttcg tgaataccaa aatcagccgc aatttgttca
    20161 taagttcgat attctcgcac tattgaagag tggccataag aaggtcttct aggcttaatt
    20221 taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat acagctaaca
    20281 tctcttcaaa agtggtacgc tgaacaccaa caagacgctt aaatcgtgca tcagttagtt
    20341 gtttacttgc ttcatcattc atagaactac tataccatat tttgtttcgc aggaagtata
    20401 atattgtcaa atactggaac gctcattgct gggatacaga ataagattgg accagcttcg
    20461 ataactggga tacctggttc aaaaccaagg tctgttgcag cgattggtgt aaagatatcg
    20521 taacctttca taaggtcttc gtttacatct ttcaccatga ctgcatcaca gtgaacatca
    20581 taaccacggt ttgaaagttc ttcttctaga gcacttttaa tttggtgact tgagttaaca
    20641 cctgcaccgc aggcagcaag aattttaatc atttggattt cctccgattt tattttttaa
    20701 tagacaagat taagcggttg cttcagcaat gtaagcataa agtttttctg gttcagaaat
    20761 ttttgatagg tcttcaagat aaccatttcc tgtgaaaaag tccatcaact gagccagaat
    20821 atttgtttga cttgaacttg aattattgat gataaagaag agcaaggata cttctacttc
    20881 cttacctggc gcaatcatat tatggaaagt caccggtttc tctaatcgaa cgaccacaac
    20941 tttttcagcc agattgtgaa caatatctgt gtgaggaatc gctacatttg gcaagtcctt
    21001 tcctagaaat tccatatcta aaccagttgg aaatgacttt tcacgcgtga tcaaggcttc
    21061 acgataagta ggagtgacaa tttctcgttc ttccaacaag cttgctacct gatcaaagag
    21121 ttgttcttga ttatccgctt ctaagcaaaa cacaaggttt ttgtcaaaga aataatctaa
    21181 taccataagg ttttcccttc tttccattaa ctttatgcca taagtataac actatatgaa
    21241 atcgttgtta attactttct gttctttttt tgtctctttt ttatattttt gttttgttta
    21301 tagtttgtta tataaaaata aacacacaaa caaatactcc aagcattttt ctgttctaat
    21361 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgttca aaacacagtt
    21421 ttgaggttgt agatgaaact gacgaagtca gctcaaaaca tggttttgag gttgtagatg
    21481 aaactgacga agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca
    21541 gtaaccatac atacggtaag gcgacgctga cgtggtttga agagattttc gaagagtata
    21601 aaaactaaaa aagcagacca tctaagcctg ctttactatt gattcttata taaatttcct
    21661 gtgaacaagg aaaggcattt ctgataactt attcttcatc catactcaag acgctgagga
    21721 aggcttcttg cggaacttca actgatccga tggatttcat gcgtttctta ccagcttttt
    21781 gtttttcaag gagtttacgc ttacgagaaa cgtcaccacc ataacattta gcaagtacgt
    21841 tcttacgaag ggccttgata tcagtacgag cgacaatctt gtgtccaata gccgcttgga
    21901 ttggaacttc aaattgttgg cgagggatga ttttcttgag tttatcaacg atgagtttcc
    21961 cacgttcgta ggcaaagtcc ttgtgaacga taaagctgag ggcatccacc ttatctccat
    22021 tgagaaggat atccattttc accagcttag atgggcgata ttctgacaat tcgtagtcaa
    22081 agcttgcata accacgtgtc gaagacttaa gtttatcaaa gaagtcaaag acaatttcag
    22141 caagaggaat ttgatagata acattgacac ggttatcatc aatatagtcc atagtcacaa
    22201 agtccccacg cttacgctga gctagctcca ttactgctcc gacgaactcc tgtggtacca
    22261 tgatttgcgc cttgacataa ggctcttcaa tggtcgcaat cttagttggg tctggaaact
    22321 cagatgggtt agacacatcc atagactcac cgtcggtcaa attaactttg taaataacag
    22381 acggagctgt catgatgagg tcaatattga actcacgctc taaacgttcc tggatcacat
    22441 ccatatggag aagtccaaga aatccacaac gaaaaccaaa tccaagtgcc tgagatgttt
    22501 ctggttcaaa ctgaagacta gcatcattca gttgcaattt ttcaagcgct tcacgcaggt
    22561 cattgtactt gtttgattcg attgggtaga gacccgcaaa gaccatagga ttcatctgct
    22621 tataaccatg taatggttct gccgcaggat tggttgccaa ggtaacggta tcacccacac
    22681 gagtatcctg aaccgtcttg atagacgccg caatgtaacc aacatcacca gtcgcaagga
    22741 aatcacgacc aaccgctttt ggtgtaaaaa taccgacttc ggtcacatca aaggtcttac
    22801 tattgctcat gagctgaatc ttatcaccag gtttgaccac tccgtccatg acacgtactt
    22861 ggaggataac cccacggtaa gcatcgtaaa cagagtcgaa aatcaaggcc ttaagtggcg
    22921 ccgtcacatc acccgttggt gctggtactt tttctacaat ttgctcgagg atttcttcaa
    22981 tcccaatacc agccttggca gaagccaaaa ctgcttcact ggcatccaaa ccaatcacat
    23041 cttcaatctc tgtacgcacg cgctccggat ctgcagccgg caggtcaatt ttattaatga
    23101 taggcatgat ttccaaatca ttatccaaag ccagataaac gttggcaaga gtttgagcct
    23161 caattccttg agccgcatcg accaccaaaa tagcaccctc acaggcagct agcgaacgtg
    23221 aaacttcata ggtaaagtca acgtgccctg gtgtgtcaat caagtggaaa atataagttt
    23281 ccccatcttt tgcagtgtaa ttcaactcga tggcattcaa cttaatagta attccacgtt
    23341 cccgctctag ctccatgcta tccaaaagct gggcctgcat ttcacgactt gaaaccgtct
    23401 ctgttttttc caaaatgcgg tctgctagag ttgattttcc gtggtcaata tgggcgataa
    23461 tagagaagtt acggatcttc tcctgtcgtt ttttcaattc ttctaagttc atgattctct
    23521 tcctttcagg gtatctattt attataaatt gtttttgata ttttgacaag accataccct
    23581 gctaagagta ctaatcttca gcgacaaagc cgtcattttc gataaagtgg tgttctgtca
    23641 ttccttggtc tgtaaagaca atcccgtgaa ggacaccacc ataaacagct cctccatcca
    23701 ttccaatctt gccatcttct gtagtccaaa gctcagatgt accgcgttct tgctgtaaca
    23761 aaccatagac cggtgtatga ccgaagacaa tggtttttcc agtatgattt tcagctccgt
    23821 ggaatggttt tctaagccat acttttttat aatctgttgt ttcatgccag tcatccaagg
    23881 tcaaatcaat acctgcgtga acaaagatat acttgtctgt ctctactaca aatggcattt
    23941 gacgaatgaa ttcgaccaag tctgccgctt cagcggcaac ccgcttggca tcttctactc
    24001 catcaactgg tgcatccaag ggacgaccta ggatagagtt aatggttgta tctccaccat
    24061 tgcgacgata atggtcataa ctttcttctg ggtcatctag ccaagtcaaa aacatatact
    24121 cgtggtttcc agacaaacag atagcccctt gattgtccac caagtccttg accatttcaa
    24181 gaacacggtg actatcctca cctctgtcaa tcaaatcacc tagaaagagc aactgggtct
    24241 gaccatccca ggttttaaga aggtcttcca gcatcccagc ttttccgtga acatctccaa
    24301 ttacataata atctgtcatc ttatttctcc ctgtttctca acaattctct ggcttgcgtc
    24361 agggctgctt ctgtcacatc atcacctgcc aacatcttgg caacttcctc cactcgctct
    24421 tcgaccgtca agagacgaac agtcgaaacc gttgaatggt cattactaat cttctcaata
    24481 aagaattgat aatctgcaat cgcaattact tgtggcaaat gggagatagc caaaacctga
    24541 ccatgctgac caattttatg aattttctga gcaatagctt gagcaacacg acctgaaact
    24601 cccgtatcca cttcatcaaa gacaatgcta gtcttgcctt ctttacgtga aaaggcagac
    24661 ttaatggcta acatgagacg agataattcc cctccagaag caaccttaac caagggttta
    24721 aagtcttctc cagggttggt tgaaatataa aactcaacca tttcatttcc ctcacgactg
    24781 aattttccct tactaaaacg aacctgaaac tgggcttttt ccatataaag atcttgcagt
    24841 tcttgtttaa tctcagcttc gagttgctga gccaaattat gacgagcaga agcaagttga
    24901 cctgccaaat tgacaagatt gacttccaac ttcttaagct ctgcttccat gtcctcagac
    24961 gaaagattat tgcctgtcaa gagattgtat tcttccgtaa tcttggcaaa ataaagcaaa
    25021 acatcatcaa cagtcccacc atacttacga gtaatagtat gaaggaggtc caaacgattc
    25081 tcaacctgca tgaggcgatt gccatcaaaa tcaaggtcct caatgataga ttccaaacgt
    25141 ttgctaatgt cttctaaaac atagtaggtc tcagacagag agcttgaaat ttcacggtat
    25201 tcaggatcat actcttcgac actttccatg tcattcatag ctgaacgaac attggccaga
    25261 cttgaaaaat cttcattgtc caacatactg taggcattgg tcagtgtatc cgcaatattt
    25321 ttgtggttga ggagtttatc tcgctcttga ttgagagcca agtcttctcc agcctgcaag
    25381 tttgctgcct caatctctgc catttgaaat tccaacattt cgatacgtgc cttgtgttcc
    25441 tgttggtttt tcttgacttc cagaacctgc ttgcgcattt tccgataggc atcaaaactc
    25501 gtttgatagg tttctttcaa gtcccaaaaa gcggcatcac caaattcatc caacatctgg
    25561 atatgcagtt ggggacgcat taactcctca tggtcatgct gaccatgaat atctacaaga
    25621 tgttgcccaa tagctcgcaa aacagacaga ttaaccatct gaccatttac acggctgata
    25681 ctacgaccat tttgcaagat ttcccgacgg atgataattt catcacctaa ttctaaacct
    25741 tgctcatcaa aaatttcctg taaaagacga ctattctcaa ctgagaaaag cccctcaatc
    25801 tctgcctttg gtgcaccatg acgaataaca tctgtcgtcg cacgagctcc caacatcata
    25861 ttcatggcat caatgataat cgacttccct gcacccgttt caccagtcag gacagtcatc
    25921 cccttttcaa aattgaggga aatagcctca ataatggcaa agttttttat cgaaatttca
    25981 agtaacatat agacctacca attttttact tgttcaaaga tttcctctgc tagacttcca
    26041 cttctggcaa tgactaaaat cgagctatca tcagtcaaac agctaaaaat cttgtctgca
    26101 aaagtctcga ttaactgagc ttttacaaaa gccgtatttc ctggaataac ttggagattg
    26161 atcatcttat ccatcaattc agccgattcg atattgtctt cagccagttg cagacttttt
    26221 acgattgatt ttggcaattc gtagacatag gtgttgtctc tcaaaggaat tttgacaata
    26281 cctaactctt tgatatctcg ggataccgtc gcctgagtgg cagtgatacc tgcttctttc
    26341 aaatgttcta caatttcttc ttgcgtgccg atttgataat ctgtcaccaa tcttctaatt
    26401 ttttcaagtc tttctttttt attcattttt aaattgacta tgcgccctct ctactgcttc
    26461 tttaatctca gcaagaatct gattgcttgc tgacttttct tttttcaaat acgctaaaaa
    26521 ttcaatattt ccatgtccac cttggatggg agaaaagtcc aagccaagga ctgaaaaacc
    26581 tgcctctact gccatagctg ttacagattc aaggacattc tgatgaatct tagcatctcg
    26641 aataattcca tttttcccaa tctgctcacg tcctgcctca aactgaggtt tgacaagtgc
    26701 taccacctga ccttgatcag ccaagacacg gtgcaaggct ggcaaaatca gactaaggga
    26761 aatgaaactc acatcaatac tggcaaagct cggctcctgc tcgaaatcag tcttttcagc
    26821 atagcgaaaa ttgaactgct ccatgctgac aactcgtggg tcttggcgta atttccaagc
    26881 caactgattg gtaccaacat cgactgcaaa gaccaacttg gcactattct gtagcatgac
    26941 atcggtaaaa cctccagtag aggccccgat atcaatcgta gtcgcgccat ccaccgacaa
    27001 atcaaagacc tgcaaggcct tttccagttt caaaccacca cggctgacat acttgagttt
    27061 ctcccccttg agttttaatt cggtatcatc tggaattttc tctcctggct tgtcaaaccg
    27121 ttctccatta aggactgcta cgactaggcc agccatcaca cctcgcttgg cctgctctct
    27181 cgtttcaaac aacccctgtt tataagctag tacatccact ctttccttag ccattgattc
    27241 tcaaactttc tactacactt acaatcgatt ctgtttcaaa gggaagctgc tgggcaattt
    27301 cttccaattt ttcattagct tgatccaggg tttggttaca aaaggcaatg gactcttcca
    27361 agcccaacaa ggcaggatag gttgattttt ctgcctgcag atccttttga ggtgtcttgc
    27421 cgatttcctc aaaactagct gtcacatcca gtacatcatc tctgacttga aaagcaagtc
    27481 caatcaattc acccacagtt ttcagcttca cctgcatttc aggtgacaat tcagctataa
    27541 tagctgccgc ttggaaggga taggctagta acttcccagt cttattggca tgaatagtct
    27601 gaagttcttc cagagacaag tgctggtgtt cgccctccat atccaaaact tgccctgcca
    27661 ccatacccag actacctgaa gcaagggata agttggcaat caagtccacc ttgatctgac
    27721 tttgcaaatc tgcctgcgca atcaaggcat atgagtctaa gaataaggca tctccagcca
    27781 aaatggccat agcttcaccg aatttcttgt gattggttaa ccgccctctt cgataatcgt
    27841 catcatccat agcaggaagg tcatcgtgaa tcaagctccc tgtatgaatc atctccaagg
    27901 cagtagctac ctgcgcgtga gcaggtttga tggtaacctg caaggcttcc agaacttcta
    27961 acaagagaaa aggccgaata cgcttgccac cagcatgaat agaatagaga acagactccc
    28021 gtaaactaga ggcaaactgc tggtctccat aaaaatcttc caaagccgac tcgacaagag
    28081 ctaatttttc ttgctttttc attcaaaatc actttctgtt ccgtcttctt gcatgacctt
    28141 taccaaggtc ttttcagcct tatccagcgt agcttggagc tcttttgaca agaccatgcc
    28201 cttttgaaag gcagtaatcg catcttccag agcaatttca ccattttcca aactttggac
    28261 aatggtttcc agttctgcta gattttcctc aaatttcttt tgttttgaca tctttaacct
    28321 ctaattctac ttgaccatct cgcatcaaaa gcgttacttg gtcttttttc ttcaaattct
    28381 caaccgaatc tacaacggac tcttcttttt tgacaatagc ataaccacgc gccacgattc
    28441 ggctagtatc caacatgagc aaagcttccg aaagtcgctt ggcctcagca accttggcgt
    28501 cataaactaa cgccatttgg ctacctaaga gcttgtccaa ctgtcctaaa cggtcttgat
    28561 agcgttggat tttggtaaca ggtgataatt gtactaattg atgagttctt gcttgaacta
    28621 attgtttgtt atcagaaatc cgagttcgca aactttgttt caaacgcagt tgcagttggt
    28681 ccaagcgttg caaataaccg tcatacaagc gctcaggttg tctaaagata acagactgac
    28741 tgcatttttt caaagcctct tgtttcttag atagaacatt tcggactgcc gttgccatcc
    28801 gtttttcctg attttgcaaa tgagctaata catccaactt ggtcacaggt gttgccagtt
    28861 cagccgccgc tgttggcgtt gcagcgcgtc gatctgccac aaaatctgcc aaggtcacat
    28921 ccgtctcatg ccccacacta gagataactg gtaaacgaga ttcaaaaata gctcgtacca
    28981 caatttcttc gttaaaggcc cagagatcct caatagaacc acctccacga ccaataatga
    29041 gcaaatccaa atcgtcccgt tgattagcac gcgcaatatt tctagcaatt tcctccgcag
    29101 ccccttcacc ttgaaccttg gtcggataaa gaaggatgtc aacacctggg aatcgcctgc
    29161 tgacggtcgt gataatatct cgaataacgg ctccactacg gctggttact acaccaattc
    29221 tcttagaaaa ttggggcaga gcttgcttga agcgttcttg aaacaggtct tcttctgtca
    29281 attttttctt aagttgttca aactgaatcg caagcgcccc aaccccatca ggctcagctt
    29341 tttcaatgat gatggagtag ctaccacttg gttcatagac ctgtacacgc ccaatcacat
    29401 tgatcttcat tccttcttcc aggtcaaacc ctaatttctg ataaatccca gaccagatgg
    29461 tcgcttgaat aactgcatgg tcatccttta gggagaaata ttggtgagta ggtcgtttac
    29521 gaaagttgga aacttgacca gttaaataga cccgttccaa gtatgggtct ttatcgaatt
    29581 tcattttcag atacttggtc aaagttgtta ccgataaata cttttccatc tccacctact
    29641 attcatttac ttgctctttc atgggtatta ttataccaaa aatatgccta aaaatctcca
    29701 tttatgtacc attatgaggg aaaaatagaa aaaggaggca aggcctccac atgtgattat
    29761 ttgctgtttc gagcttcttc caaaatcttt gcaatcttgg tcgtcaacag gtcgatagcc
    29821 acggtattgc taaccccttc aggaatgacg atatcagcat aacgcttagt tgactcgata
    29881 aactggtggt acattggttt gaccacacct aagtactggt tgataacgct atcaaggcta
    29941 cggccacgtt cctccatatc acgcttgata cgacgaataa tgcgcacatc gtcatccgta
    30001 tccacaaaaa tcttgatatc catcaaatcg cgcagacgct tgtcctccaa gaccaaaatg
    30061 ccctcaacga taaagacatc ttgaggctcc tgacgatagg tcttgctact ccgtgtatgc
    30121 tctgtatagt cgtaggtcgg gatgtccacc ggacgccctg ccaacaattc cttaatctgc
    30181 tcgatcatca agtctgtatc aaaggcaaaa ggatggtcat agttggtttt gacacgctct
    30241 tcaaaggtca aatgagactg atccttgtag tatgaatcat gctcaatcat ggaaatcttt
    30301 tcatcaggaa aatgcgataa aatggctctt gaaacactgg ttttaccacc accagaacca
    30361 cctgtcactc caataatgat tggtctattt tgcatgctat cctccgttat tttatccgtc
    30421 gtctattcta tcacattttt tacaaaattt atagtctcat cagcaaaaaa caccagagtc
    30481 ttccctctga tgttcgacag ttttaacgaa agccctgtag ggtttgagca agcatctgca
    30541 agaaagccag tctccctctt tcctggctag gagctttggc aatccataaa ccaaaatcaa
    30601 tgacagactt aggtgcctgg taatgatgcg tcatgaggta aagtgacaac ccttgactca
    30661 aattggccat gaccgattgg tatttttcat ttctgtctaa attttgtata gcaagacgaa
    30721 acaggtgact caactcacta ttttcattta tttctttttg ttgaagaagt tgctccaccc
    30781 tttctcgaaa ctcatttcgc atcatggaat tatcacacca aatcctgggc ctaagttccc
    30841 accagaacct gtaatggact ctaaatattt atctgaaaga attttaaatt gcttcatttc
    30901 acacctctaa atttctatat agattatttg agtacctaca actcgcaaca attggaatat
    30961 tataattccc aaaaccattc tactattagt atggggtttt atcaagcaat tgttatctat
    31021 cacccgattt ttattcctaa acgatctagc taaaaacctt ccttggctta tagagattgc
    31081 cccgtttttc tagaatggct aacaatttat catcttcaaa ggcagccagt tctttgtccg
    31141 tttggtctag ctcaataaaa cgaccaaagc gaacttctgt agcctcttct ggagttagga
    31201 aaactttgac aaggtcacct gtcccaatct ctaaaggatg gagaaaatct aattgcccag
    31261 cctctacttt ttcagcaatt tcctccaagg caagagcgtc ttctaattgt aagccagcag
    31321 cactagtacg agtcaaatgg gacatatgag ccgcataacc aagcttttca cccaaatcaa
    31381 ctgacaaagt acggatgtaa gtccctttac tgcattttac acgaaaagtg aatcgagcaa
    31441 gttggccatc ataagaaatc ggacttgttc gctcaaattg ataaatggtc acctgacgtt
    31501 ctggacgctc cacttcctga ccagcacgcg catactcata gagcttgcga ccattaacct
    31561 taactgccga atacataggg ggaatctggg taataggccc agtcaagcta gcaatcgctt
    31621 catcaacaag cttttcatcc aagggagaca aaacaggggt ttctgcgatc acttccccac
    31681 tagcatcctc agtcgtcgtg gaataaccca gagtaatttc cccctcatag atcttaccct
    31741 cgtcctgcat aaactcgacc atgcgtgtcg ccttgccaac cgcaatcggc aaaacaccca
    31801 ccacatccgg atccaaggtt ccaccatgac caattttctt ggttcccaaa atcttacgca
    31861 gtttaaaaac cgcatcatgc gaggtcattc ctgcttcttt ttttaagttg ataataccgt
    31921 tcatttttgc tttctactcc cccttcagtg cttcgaactt cgcttttttc cgggccaatt
    31981 tttactgagg cgtcgtctac cttttattct cttttttaca aaatttaatt aactataatt
    32041 ctttgtaatt cctcaatctc tggaggagga caattgttct gtttttgaat atgttgtaat
    32101 acatttcgtc tgtcatctaa agataataat gggagtatac ttttgatgcc atctaaataa
    32161 aaaatatcat tctctatttt atcggtctcc attaatttca gaaacatttt tttcaacaaa
    32221 tcaaaattgt taagttcttc atgattcaat ttataattca tccctcgtaa agataatt
//
LOCUS       DAVMCG010000021        31113 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVMCG010000021 DAVMCG010000000
VERSION     DAVMCG010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31113
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.021"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            4..77
                     /locus_tag="VYP66_001172"
     tRNA            4..77
                     /locus_tag="VYP66_001172"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38..40,aa:Asn,seq:gtt)
     gene            complement(196..969)
                     /locus_tag="VYP66_001173"
                     /pseudo
     CDS             complement(196..969)
                     /locus_tag="VYP66_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1234..1470
                     /locus_tag="VYP66_001174"
     CDS             1234..1470
                     /locus_tag="VYP66_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1850730.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1701..2987
                     /locus_tag="VYP66_001175"
     CDS             1701..2987
                     /locus_tag="VYP66_001175"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1850731.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            3188..3655
                     /locus_tag="VYP66_001176"
     CDS             3188..3655
                     /locus_tag="VYP66_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1850732.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            3688..3781
                     /gene="ffs"
                     /locus_tag="VYP66_001177"
     ncRNA           3688..3781
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYP66_001177"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            3841..4284
                     /locus_tag="VYP66_001178"
     CDS             3841..4284
                     /locus_tag="VYP66_001178"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1850733.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            4286..4801
                     /locus_tag="VYP66_001179"
     CDS             4286..4801
                     /locus_tag="VYP66_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1850734.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            4815..6176
                     /gene="radA"
                     /locus_tag="VYP66_001180"
     CDS             4815..6176
                     /gene="radA"
                     /locus_tag="VYP66_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1850735.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLQQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            6249..6746
                     /locus_tag="VYP66_001181"
     CDS             6249..6746
                     /locus_tag="VYP66_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1850736.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            6771..6980
                     /locus_tag="VYP66_001182"
     CDS             6771..6980
                     /locus_tag="VYP66_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850737.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            6962..7585
                     /locus_tag="VYP66_001183"
     CDS             6962..7585
                     /locus_tag="VYP66_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1850738.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            7986..8300
                     /locus_tag="VYP66_001184"
     CDS             7986..8300
                     /locus_tag="VYP66_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1850739.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            8316..8702
                     /locus_tag="VYP66_001185"
     CDS             8316..8702
                     /locus_tag="VYP66_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1850740.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            8731..10116
                     /locus_tag="VYP66_001186"
     CDS             8731..10116
                     /locus_tag="VYP66_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1850741.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            10119..10271
                     /locus_tag="VYP66_001187"
     CDS             10119..10271
                     /locus_tag="VYP66_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1850742.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            10294..11712
                     /locus_tag="VYP66_001188"
     CDS             10294..11712
                     /locus_tag="VYP66_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV1850743.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEI
                     RLRSKLKSVLIVHYLKILYNRN"
     gene            11761..11844
                     /locus_tag="VYP66_001189"
     CDS             11761..11844
                     /locus_tag="VYP66_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV1850744.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            11969..12706
                     /gene="erm(B)"
                     /locus_tag="VYP66_001190"
     CDS             11969..12706
                     /gene="erm(B)"
                     /locus_tag="VYP66_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV1850745.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(12963..14210)
                     /locus_tag="VYP66_001191"
     CDS             complement(12963..14210)
                     /locus_tag="VYP66_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1850746.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            14390..14611
                     /locus_tag="VYP66_001192"
     CDS             14390..14611
                     /locus_tag="VYP66_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850747.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            14728..15225
                     /locus_tag="VYP66_001193"
     CDS             14728..15225
                     /locus_tag="VYP66_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV1850748.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            15200..15706
                     /locus_tag="VYP66_001194"
     CDS             15200..15706
                     /locus_tag="VYP66_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1850749.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            15690..18137
                     /locus_tag="VYP66_001195"
     CDS             15690..18137
                     /locus_tag="VYP66_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1850750.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            18140..20317
                     /locus_tag="VYP66_001196"
     CDS             18140..20317
                     /locus_tag="VYP66_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1850751.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            20314..21315
                     /locus_tag="VYP66_001197"
     CDS             20314..21315
                     /locus_tag="VYP66_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV1850752.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            21312..22244
                     /locus_tag="VYP66_001198"
     CDS             21312..22244
                     /locus_tag="VYP66_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1850753.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            22489..22605
                     /locus_tag="VYP66_001199"
     CDS             22489..22605
                     /locus_tag="VYP66_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV1850754.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            22621..24540
                     /gene="tet(M)"
                     /locus_tag="VYP66_001200"
     CDS             22621..24540
                     /gene="tet(M)"
                     /locus_tag="VYP66_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV1850755.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            24659..24826
                     /locus_tag="VYP66_001201"
     CDS             24659..24826
                     /locus_tag="VYP66_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV1850756.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(24886..25239)
                     /locus_tag="VYP66_001202"
     CDS             complement(24886..25239)
                     /locus_tag="VYP66_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1850757.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            25744..26166
                     /locus_tag="VYP66_001203"
     CDS             25744..26166
                     /locus_tag="VYP66_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1850758.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            26163..26393
                     /locus_tag="VYP66_001204"
     CDS             26163..26393
                     /locus_tag="VYP66_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1850759.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            26854..27057
                     /locus_tag="VYP66_001205"
     CDS             26854..27057
                     /locus_tag="VYP66_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEV1850760.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            27139..28356
                     /locus_tag="VYP66_001206"
     CDS             27139..28356
                     /locus_tag="VYP66_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1850761.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            28618..29586
                     /locus_tag="VYP66_001207"
     CDS             28618..29586
                     /locus_tag="VYP66_001207"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1850762.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(29720..30001)
                     /locus_tag="VYP66_001208"
                     /pseudo
     CDS             complement(29720..30001)
                     /locus_tag="VYP66_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(30127..30360)
                     /locus_tag="VYP66_001209"
     CDS             complement(30127..30360)
                     /locus_tag="VYP66_001209"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850763.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
     gene            complement(30353..30469)
                     /locus_tag="VYP66_001210"
     CDS             complement(30353..30469)
                     /locus_tag="VYP66_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1850764.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            complement(30684..31034)
                     /locus_tag="VYP66_001211"
     CDS             complement(30684..31034)
                     /locus_tag="VYP66_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1850765.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
BASE COUNT         9749 a         5374 c         6670 g         9320 t
ORIGIN      
        1 taatccgcca tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc
       61 gagtcctact ggcggagtaa tttagttaag aggtttagac ctctttttta ttatgtaata
      121 ataatctatt tcgtgttata gtaaaatgaa ccaaaaatag tggctctttg tcaactgtag
      181 tgggttgaag aaaagctaag cttgagaaag gacaaatttc gtcctttctt ttttgaagtt
      241 ttcaaagttc ctaaaaccaa aggcattgta cttgataagt ttgatgagat tattggtggc
      301 ttccagtttg gcgttggaat aaggtaattg aaggccgttg acgatttttt ctttatcttt
      361 gaggaaggtt ttaaacagag tctgaaaaag aggtggaaaa gcaagagctg atagagatta
      421 tagtggtgtt tcaagtcttc ggaatagctc aaaagtttat ctagaatttc tttattagtc
      481 aagtgcatac gaaaagtagg gcgataaaat cgtttatcac tcagtttctg actatcttgt
      541 tgaatgagct ttcagtatcg cttgatagcc ttgtattcat gggatttcgg atgatggctt
      601 gtgttctgct ctcaagaaca gttatgatat tgagcttatc aaagtcttga gcaataaagc
      661 tcatctccat ctcccgattg aaacagtcac tccccggact gtttcaacgt cctaggacat
      721 aatctcagga agacgcgaaa aatcatgctc aaagtgaaaa tcattgatct tgcgaatgac
      781 agttgaagtt gaaatagaca actgatgatc aatgtcggtc atagaagtct ttttaattag
      841 cttctgagca atcttttggt tgatgataca aggaatttga tgattcttct tgacgataga
      901 agtttcagcg accctcattt ttgaacagtg atagcactta aaacggcctt ttctaagaag
      961 aattctagtt tgaatttttt atactagaaa atcagaacca taatacctat ataaaaatat
     1021 tatagttcta ataggattta cccaaaagtt ttaaggcggt ctttttagaa ctttaatcgt
     1081 ttgaaattta ggtagcaaat ttgtttctat tctgtcaact tttcctattt ttatcttgtt
     1141 gagcctggta ttttaacaat tcaggaattg atagtgaatg tgtaaaattt tttgttagaa
     1201 taagtttata aaaaagaaaa ggagtatttg attatgttac aaaaaattta tgagcagatg
     1261 gctaatttct atgatagtat tgaagaagag tatggtccta catttggtga taattttgac
     1321 tgggaacatg ttcattttaa atttttaatt tattatttag tgagatatgg cattggttgt
     1381 cgtagggatt ttatcgttta ccattatcgt gttgcttatc gtttgtatct tgaaaaattg
     1441 gtaatgaatc ggggttttat ttcttgttga ggtaatttta gtaaatttcc gaactaattt
     1501 actcttttat ggaaagatga tagtaaatag ctagtaattt ttctaaatca ttttttaata
     1561 gttggaaata gcaaatcttt ctattgtttc ttcttgataa aaaggcgatt ttttattata
     1621 ataaattgta agatataatt gcaggtgaga gtcctgccat gtatgtgaga aaggaagagc
     1681 ctgagggctc agacaagatt atgacttcag ttgttgttgt aggtacccaa tggggtgatg
     1741 aaggtaaagg gaagattaca gacttccttt cagcgaatgc agaagtgatt gcacgttacc
     1801 aaggtggtga taatgctggt cacacgattg tgattgacgg taagaaattt aagttgcact
     1861 tgattccatc tgggattttc ttccctgaaa aaatatctgt cattgggaat ggtatggttg
     1921 taaatcctaa atctcttgta aaagagttga gctatcttca tgaggaaggt gtaacaactg
     1981 ataacttgcg tatttctgat cgtgcgcatg ttattttgcc ttatcatatc gagttggatc
     2041 gcttgcaaga agaagctaag ggcgacaata agattggtac gacaattaag ggaattggtc
     2101 cagcttatat ggacaaggct gctcgtgttg gaattcgtat tgcagatctt ttagataaag
     2161 atattttccg tgagcgttta gaacgtaacc ttgctgaaaa gaatcgtctt tttgaaaaat
     2221 tgtatgacag taaagcgatt gttttcgatg atatttttga agaatattac gaatatggtc
     2281 aacaaatcaa gaaatacgtg atagatacat ctgttatctt gaatgatgcg cttgataatg
     2341 gcaaacgtgt gctttttgaa ggtgcacaag gtgttatgct agatatcgac caaggtactt
     2401 atccatttgt tacgtcatca aaccctgtag ctggtggtgt gacaattggt tctggtgtcg
     2461 gtccaagcaa gattgacaag gttgtaggtg tatgtaaagc ttatacgagt cgtgtaggag
     2521 atggtccttt cccaactgag ttgtttgatg aagtgggaga acgtatccgt gaagtgggtc
     2581 atgagtatgg tacaacaact ggtcgtccac gtcgtgtagg ttggtttgac tcagttgtga
     2641 tgcgtcatag ccgtcgtgtt tctggtatta ctaacctttc tttgaactct attgatgttt
     2701 tgagcggttt ggatactgtg aaaatctgtg tggcctatga tcttgacggt caacgtattg
     2761 actactatcc agctagtctt gagcaattga aacgttgcaa gcctatctat gaagagttgc
     2821 caggttggtc agaagatatt accggagttc gcaatttgga agatcttcct gagaatgcgc
     2881 gtaactatgt tcgtcgtgtg agtgaattgg ttggcgttcg tatttctact ttctcagtag
     2941 gtcctggtcg tgaacaaaca aatattttag aaagtgtttg gtcctaagag atttttaaga
     3001 tttgtttaag ataggtcggg tatactatag acggttacaa gaagacctcc taacttgttg
     3061 taacaaatat cctaaacttt tctttttcat aataatctcc ctatagagtc accgcattcg
     3121 gtggcttttt ttgtgttggg attcatgata taataataaa atcgataagt aggaaaagag
     3181 aaaagagatg tattatacgc ttgaagaaaa agaagtcttt atgagggagg ctttgagaga
     3241 ggctgagatt gctcttgaac acgatgaaat tccaattggt tgtgtgattg tcaaagatgg
     3301 ggaaatcatt ggtcgtgggc ataatgcgcg tgaggaatta cagcgagcgg ttatgcatgc
     3361 ggaaattatg gctatagagg atgcgaactt gagtgaggag agctggcgct tgctggattg
     3421 cacacttttt gtgaccattg aaccttgtgt catgtgtagt ggagcgattg ggcttgcccg
     3481 cattccaaat gtggtctatg gggctaaaaa ccagaaattt ggcgctgctg ggagtttgta
     3541 caatatcttg acagatgagc gtctcaatca tcgtgtggag gttgaaatag gaattttgga
     3601 agatgaatgc gcagctatca tgcaggattt ttttagaaat agacggaaaa aataattttg
     3661 cttttaaaat gaataggaat gtgatataat aaatagtgga gcaacagttc tgcgtgaagc
     3721 gggtcagggg aggaatccag cagccctaag cgatttgaat tgtgtgctct tttttcgtgc
     3781 tttttccgaa taaataagat agaataatct agaataaatg ataatagaaa agagaaaatt
     3841 atgaaaattc gtggttttga attggtttca agttttacag atgaaaattt attgcccaag
     3901 cgtgagacag cgcatgcggc tggttacgac ttaaaggttg ctgtgcgtac agttgttgcg
     3961 ccaggagaga ttgtcttggt tccgacaggg gttaaggctt atatgcagcc gactgaggtt
     4021 ctctacctct atgatcgttc ttcaaatcct cgtaagaagg gcttggtttt aattaactca
     4081 gttggggtca ttgatgggga ttattatgga aatcctggaa atgaagggca tatttttgcg
     4141 cagatgaaga atatcacaga ccaagaggtt gttcttgaag ttggggaacg tattgtccag
     4201 gctgtttttg ctactttctt aattgcagat ggagatgcag ctggtggcgt tcgaactggt
     4261 ggatttggat cgacagggca ctagaatgaa gattatcttt gtacgtcatg gggagccaga
     4321 ttaccgtgag ttagaggagc gttcttatat aggatttggg atagatttgg cacccttgtc
     4381 tgagatggga cggcagcaag tccagaaatt gagcaaaaat cctttactct cgtcagctga
     4441 aataatcgta tcttctgcag tcacaagagc tttagaaacg gcttcgtatg tggtctgtgc
     4501 tacgggtctt cctttaagag tagagccttt attacatgaa tggcaggtct ataaaacagg
     4561 aatagaaaac tttgaaacag ctagaagact gtttttagaa aacaaggggg agttgcttcc
     4621 taatagtcct attcaatatg agacagctac ggaaatgaag tctcggtttc tagaatgtat
     4681 gtctaagtat cgagaacatc agactgtggt agttgttgct catcgaatgc tcatgcgcca
     4741 gtttgtgcca aatgagaaga ttgatttttg ccaagtgatt gagtgtgagt tagagatata
     4801 ggaagaggtt tgtcatcgca aagaaaaaag cgacatttgt atgtcaaaat tgtgggtata
     4861 attcccctaa atatctggga cgttgcccca actgtggatc ttggtcttct tttgtggaag
     4921 aggttgaggt tgccgaggtc aagaatgcgc gtgtgtcctt gacaggtgag aaaaccaagc
     4981 ccatgaaact agctgaggtg acttccatca atgtcaatcg aaccaagacg gagatggagg
     5041 aattcaaccg tgtgcttgga ggcggagtgg taccaggaag tctcgtcctc atcggtgggg
     5101 atcctgggat tgggaaatca actcttctcc aacaagtctc aacccagttg tcccaagtgg
     5161 ggacagttct ctatgtcagt ggggaggagt ctgcccagca gattaaacta cgtgcagagc
     5221 gcttaggtga tattgatagt gagttttatc tctatgcaga gaccaatatg cagagtgttc
     5281 gtgcagaagt ggagcgtatc cagccagact ttcttattat tgattccatc cagaccatca
     5341 tgtctcctga gatttcaggg gtgcaggggt ctgtttctca ggtacgtgaa gtgaccgctg
     5401 aactcatgca gttggccaag accaataaca ttgccatctt tatcgtaggt catgtgacca
     5461 aagaaggaac cttggctggg cctcgtatgt tggagcatat ggtggatacg gtgctttact
     5521 ttgaagggga gcgtcaccac acctttcgta ttttgagagc ggtcaaaaat cgttttggtt
     5581 ccactaatga gattgggatt tttgagatgc agtcgggcgg cttggttgag gtactcaatc
     5641 cgagtcaagt tttcctagaa gagcgtttgg atggggcgac tggttcctcc atcgttgtaa
     5701 ccatggaagg gacgcgtccg attttggcgg aggttcaggc tttagtaaca ccgaccatgt
     5761 ttggaaatgc caagcgtact acgacaggac ttgattttaa ccgtgctagc ttgattatgg
     5821 ctgttttgga aaaacgggca gggcttctct tgcaaaatca ggatgcctat ctcaaatctg
     5881 ctggtggtgt taaattggat gaacctgcca ttgacttggc tgttgcagtt gctattgctt
     5941 cgagctacaa agacaaacca actaatcctc aggaatgttt tgtcggagaa ctgggcttga
     6001 caggagagat tcggcgcgtg aatcgtattg agcaacgcat caacgaagct gctaaactgg
     6061 gctttactaa gatttatgta cctaagaatt ccttgacagg aatcactctg cctaaggaaa
     6121 ttcaggtcat tggcgtgaca acgattcagg aagttttgaa aaaggtcttt gcataatccg
     6181 tgacaaattc tcttaaaaat gataagatag gagaaatatt tgactatcaa attttcaagg
     6241 agggaatcgt gtcgtatttt gaacagttta tgcaagccaa tcaggcttat gttgccctac
     6301 atgggcagtt aaatctgcca cttaaaccca aaacaagagt agctattgtg acctgtatgg
     6361 actctcgtct gcacgttgcg caagctctgg gcttggcact tggggatgct catatcttgc
     6421 ggaatgcagg tggtcgagtg actgaagaca tgattcgttc gctagttatt tcccagcaac
     6481 aaatggggac aagagagatt gtggtattgc accatacaga ctgtggtgct cagacctttg
     6541 aaaatgaacc ttttcaggag tatttaaaag aggaattagg tgtagatgtg tcagaccagg
     6601 acttcttgcc cttccaagat atagaagaga gtgtacgcga ggatatgcaa ctgcttatcg
     6661 agtctcccct aataccagac gatgtcatta tctctggtgc tatttacaat gttgatacag
     6721 gaagtatgac agtcgtagaa ttataaatac ttcatttaga aagaaagtgt atgaagaaaa
     6781 gcagtatttt atttattttt attttattgc tatgtattgg tttacagtat gaaaccatct
     6841 actatacgga cggttcgagg tcaggtgcgg aatatggact aatgggaatt tctatctttc
     6901 tagctctctt ttacatgatt ccggctcttt attttctctt ccgtattggg aaaaatggga
     6961 attgccaaag aaggttttga ttctgtcttt attgggaggg atgttccttt caggatggtt
     7021 gtctagtttt gctaatactt atatccatga tttactgggg gttcttttcc cagatagtac
     7081 atttttaaat gcctttgaaa gtgctattgt ggctcctttg gtagaagaac ccttgaaatt
     7141 attgccactt gtttttgttt tggctttgat tcctgtgcga aaattaaaat ctttgttttt
     7201 acttggaatt gcttccggtt tgggattcca aatgattgag gatattggtt atattcgtac
     7261 ggatttgcca gagggctttg actttactat ttcgcgaatt ttagagcgta tcatctcagg
     7321 aattgcctct cactggactt tttcaggtct agctgtagta ggtgtttact tgctttacag
     7381 agcctataaa ggacagaagg ttggcaagaa acagggactt atttttctag gtttagcctt
     7441 gggaactcac ttcttgttta actctccttt tgtggagttg gaaacagagt tgcctttagc
     7501 gattccagtg gttacggcta ttgctctcta tggtttttat catgcttatt gctttgttga
     7561 gaaacacaat gagttgatga cctagaatat ttttcaaaag aatgatgcaa gggtacaaat
     7621 atggtgccct tcttttattt ttgtttaata aaaatagcat aaaaatctag ttatccgcat
     7681 aaaaactgga cttatcacac tttatcaagg tcaaaaccac tcaatttact actaatttac
     7741 tacttatgaa tgagctttga tacgacgatt tatccttgaa aagtgaagat ataaagatac
     7801 ttccaataaa atttgaatat ttaataggta gacacttcaa aaaatgaggt gtctattttt
     7861 ttacccgatt ttgaaaggaa gtgaacttat gaaaacaaaa aatcaagaat caaaaggtcg
     7921 ttccccactc tttaagacca tcaaacattc attcagccaa taaaaaagaa aggataggta
     7981 aaaatatgga acttaaattt gtgattccca acatggaaaa aacattcggc aatttagaat
     8041 ttgctggcga ggataaagtc gttcagcgaa gaatcaacgg acggctaact gtcttatcaa
     8101 gaagctataa tctctattct gatgttcaaa gagcagatga tattgtggtg gtgcttcctg
     8161 ctgaagctgg cgaaaaacat ttcggctttg aggaacgtgt gaagttagtc aatccacgta
     8221 ttaccgcaga gggctacaaa atcggcactc gtggttttac aaattacctt ttacatgctg
     8281 acgacatgat aaaagaataa agaaagagag gaaaaatgat gagattagca aatggcattg
     8341 tattagataa agacacgact tttggagaat tgaaattctc tgctctacgt cgtgaagtga
     8401 gaatccaaaa tgaagacggg tcggtttcag atgaaatcaa ggaacgtacc tatgacttaa
     8461 aatccaaagg acaaggacgc atgattcaag taagtattcc tgccagcgtg cctttgaaag
     8521 agtttgatta taacgcacgg gtggaactta tcaatcccat tgcggacacc gttgctactg
     8581 ccacctatca aggagcagat gttgactggt atatcaaggc agacgatatt gtgctgacaa
     8641 aggattctag ttcattcaaa gctcaaccac aagcaaagaa agaaccgaca caagacaaat
     8701 agtcgctagg tagaaaggag actttttcgc atgaaacagc gtggtaaaag gattcgccca
     8761 tctggtaaag atttagtctt tcattttacg atagcgtcac tcctgcctgt tttcctgctg
     8821 gttgtcggac tgtttcatgt gaagacaatc cagcagatca actggcagga ttttaaccta
     8881 tcacaagcag ataagattga cattccctat ttaattatca gtttcagtgt cgcaattctt
     8941 atctgcttgc tggtagcgtt tgtattcaaa cgggttcgct atgatacggt taaacaactt
     9001 taccaccgtc aaaaactggc aaagatgata cttgaaaaca agtggtatga atctgaacag
     9061 gtcaaaacag agggtttctt taaagatagt gctggtcgta caaaggaaaa gataacctac
     9121 ttccctaaaa tgtattatcg acttaaaaat ggcttgatac agatacgggt ggaaatcacg
     9181 ctgggaaaat atcaagacca actcttacac ttggaaaaga aattagagag tggcttgtac
     9241 tgtgagctga cggataaaga gttaaaggat tcctatgtgg aatatacttt gctctatgac
     9301 accatagcca gtcgtatttc tattgatgaa gtagaagcta aagatggtaa acttcgctta
     9361 atgaaaaacg tatggtggga atatgataag ctccctcata tgttgattgc tggtggtaca
     9421 ggtggcggta aaacttactt tatactgaca ctgattgaag ccttgcttca tacagattca
     9481 aaactgtata ttcttgaccc gaaaaatgct gatcttgcgg acttaggttc tgtgatggca
     9541 aatgtctact atagaaaaga agacttgctt tcttgcattg aaacattcta tgaagaaatg
     9601 atgaaacgta gtgaggaaat gaagcagatg aagaactata agactggcaa aaattatgct
     9661 tacttaggtc tcccggcaca cttcttaatc tttgatgaat acgtcgcttt catggaaatg
     9721 ctgggaacaa aagaaaacac cgcagttatg aataagctga aacagattgt catgttaggt
     9781 cgtcaagctg gcttctttct aatactggct tgtcaacgtc cagacgcaaa atatttaggc
     9841 gacggaatcc gtgatcagtt taatttcaga gtggctttag gtcgtatgtc tgaaatgggc
     9901 tatggcatga tgtttggcag tgacgtacaa aaggatttct tcttaaagcg aatcaaaggt
     9961 cgtggctatg ttgatgtagg aacaagtgtc atatcagagt tttatactcc ccttgtacca
    10021 aaaggatatg atttcttgga ggaaattaaa aagttatcca acagcagaca gtccacgcag
    10081 gcgacgtgcg aagcggaagt cgcaggtgtg gactgatctt gctggctggt gtggcaatag
    10141 ccacgccagc acttaacccc ccgtatctaa caggggggta caaatcgaca ggaaacagtc
    10201 aaaaaaacat tagaaaatcc tttggttaca agggatttac aaaatttcag cgtatgtcaa
    10261 atgggcttta aaagttgaca tacgcctttt tgattggagg gatttttact gaatgaacaa
    10321 acttggttac agcatttaaa agaaaaacgc ttggcttatg gactatctca aaaccgttta
    10381 gctgttgcga ctggtattac aaggcagtat ctaagcgata ttgaaacagg aaaagtcaag
    10441 ccatcagagg atttacagca gtccctttgg gaagctctgg aacgcttcaa tcccgacgct
    10501 ccccttgaaa tgctgtttga ttatgtaaga attcgctttc cgacaacaga cgtacagcag
    10561 gtggtcgaaa acatcttaca actgaaactg tcctattttc ttcatgagga ctatggtttc
    10621 tattcttatt cagagcatta tgctttaggc gacatattcg tcctttgctc ccatgaactg
    10681 gacaaaggag ttctggtgga attgaaaggt cgtgggtgca gacaatttga aagctatctt
    10741 ctggcacaac aaagaagctg gtatgagttc tttatggacg ttttggtggc tggcggtgtg
    10801 atgaaacgcc ttgaccttgc cattaacgat aagacaggga ttttaaatat ccctgtactc
    10861 actgaaaagt gccaacagga agaatgtatc tccgtcttcc gcagttttaa aagctatcgc
    10921 agtggcgaac tggtacgcaa agaggaaaag gaatgtatgg gaaacaccct ctatatcggt
    10981 tcattacaaa gtgaagttta tttctgtatc tatgaaaagg actacgagca gtacaagaaa
    11041 aatgatattc ccattgaaga cgcagaagta aaaaaccgtt ttgagattcg attgaaaaat
    11101 gagcgtgcct attatgcagt ccgtgattta ctcgtctatg acaatccaga gcataccgcc
    11161 tttaaaatta tcaatcggta tatccgtttt gtagataaag acgattccaa acctcgttct
    11221 gattggaaac tgaatgaaga atgggcttgg tttattggga acaatcgtga acgattaaaa
    11281 ctaaccacaa aaccagagcc ttactccttc caaaggacgc tgaactggct atctcatcaa
    11341 gttgccccga ccttaaaggt tgcgattaaa cttgatgaaa tcaaccagac gcaggttgta
    11401 aaagacattc tcgaccatgc gaaactgaca gaccgacaca agcagatttt gaagcaacag
    11461 tcagtaaaag aacaggacgt gataacaaca aaaaaaggat atctgtcaac cataccagtt
    11521 gacagatatc caaaaaaaga tataatggga gataagacgg ttcgtgttcg tgctgacttg
    11581 caccatatca taaaaatcga aacagcaaag aatggcggaa acgtaaaaga agttatggaa
    11641 ataagactta gaagcaaact taagagtgtg ttgatagtgc attatcttaa aattttgtat
    11701 aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc
    11761 atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa
    11821 aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta
    11881 tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg tatttgttta
    11941 tagatgtaat cacttcagga gagattacat gaacaaaaat ataaaatatt ctcaaaactt
    12001 tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga
    12061 taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag
    12121 taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt
    12181 aaaactgaat actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa
    12241 caaacagagg tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa
    12301 aaaagtggtt tttgaaagcc gtgcgtctga catctatctg attgttgaag aaggattcta
    12361 caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat
    12421 tcagcaattg cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt
    12481 cttaataaaa cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac
    12541 gtactttgtt tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt
    12601 tcatcaagca atgaaacacg ccaaagtaaa caatttaagt accattactt atgagcaagt
    12661 attgtctatt tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct
    12721 tttttaaatt tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac
    12781 tactgacagc ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat
    12841 aaggggtaca aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtggg
    12901 atatctgtca actggtatgg ttgactaaaa atacttccta cgaaaatgta gggggtattt
    12961 ttttacgaaa aaatacaatc gattcttaaa aagaaaaatt tttgattggc aaaaccataa
    13021 caagttcgtt ttagggtttt gattttgcga ttgatgcctt ctaaaggacc attagagtat
    13081 tcaaatttag cgctatttaa gacatatttt ctgttttgac gaagggtttg aatagcagta
    13141 tccatttctg tattggtttt ttggtagtct aagatggttg actctagtaa ttcactattg
    13201 cgctcgttta gggctttcgt gatatcttgg taagtttggt atacttcagc gaacttggaa
    13261 aatttactag taatgagatc aacagcattt tggcgagtca tatattgttt aacgccgcga
    13321 agaaaaacta cttcttcagg gtgaagatct tcagcttttt tatggaatag cttccaatgt
    13381 gacttcataa ttttatattc ttggctctgt ttatcaagtt gctttaggat agagatacga
    13441 caattgtcca aagcgcgacc agctaattgt acaaggtgga agcgatcaat aatgatattg
    13501 gcattaggga aaaggcgata gataaaactt tgatattgag catttaaatc aattacaact
    13561 gattgaacgc attcgcgttc ggcttttgaa taacgacttt caaaataatc aacaatggta
    13621 ggtgatagac gatcctgtaa ctttgtgaca atttggtggg tttcagcgtc acaacagata
    13681 aaggacatca cagacttaat tgaacgaaac tcgtcaaaac atagatgctt aggcaactta
    13741 gccacacgat agtgtggttc catgcgctct aagattgttc gacgaacact gctaggagag
    13801 cagtgacaca tttcagcaat aagctgacca gataagcctt tacgagctaa aagcatgatt
    13861 tgatttttga gatcactgga taaggtttga ttttctttgg ttaaattagt aatagcacca
    13921 aaagtagtat ggcatgattt acatttatag cgttgtttac gaagctctag ttcatatctt
    13981 ctcccattta aacttgccag tcgtacatga gttttgcgaa agccatcctt attaactgtg
    14041 ggaaagccac agttacgaca acgattaatc ggataagaaa gagtagctgt tattagcgtt
    14101 atatactctt taacagaatc gttgttgtgt tcagcttctt caacagaaat aattttaata
    14161 tttttatctt taattccaag aatatttagg atagaatcat tatgggacat ttgtttaacc
    14221 ttctttcatg atttttgtgg tgaattgatt gtataacgag gggacagcaa atgtcctctt
    14281 ttttgtataa aaaaatctgg catggaatct ctatccatac cagaaagtgt ataccccaaa
    14341 aaaataactc aaatacaaat tcattgaata tagagaggag aacattttta tgaattttgg
    14401 acaaaacctt tataactggt ttctatcaaa cgctcaatca ctggtgcttt tagcaatcgt
    14461 tgtgattggc ttgtatcttg gcttcaagcg tgagtttagc aaactgattg gctttttaat
    14521 tattgcgatt attgcggttg gcttagtctt caacgctgct ggagtaaaag acattttact
    14581 agagctattc aatcgcatta ttggtgctta aataaaaccg ttcttttgtg gaatataagt
    14641 ggttttctta tgttccgcaa aggaatggta caccaaacga agtgcggtag ggatttttga
    14701 atctctacaa agaaaggacg tgaatatatg gacgatatgc aagtctatat tgcgaattta
    14761 ggcaaataca atgagggcga attggtcggt gcgtggttta cctttcccat tgactttgag
    14821 gaagtcaaag agaaaatcgg cttgaatgat gaatatgagg aatacgccat tcatgactac
    14881 gagttaccct ttacggttga cgaatacact tccattggcg aactcaatcg actatgggaa
    14941 atggtatcgg aattacccga agaattacaa tcggagctat ctgctctgct cactcatttt
    15001 tcaagcattg aagaactaag cgaacatcaa gaggatatta tcattcattc cgattgtgat
    15061 gatatgtatg acgtggcacg ctactacatt gaagaaacgg gtgctttagg cgaagtacca
    15121 gctagtcttc aaaactatat tgattatcaa gcctatggtc gggatttaga cctttcagga
    15181 acgtttatct caaccaatca tgggattttt gaaatcgtct attaaatctg tcggtacatt
    15241 actactggca gattttctat tttacggggt ggctcaatca gctaccccta ttttttatga
    15301 aaggattgat tacatgaaga aaatacgaag ctataccagt atctggtctg tggaaaaggt
    15361 actgtattct atcaatgatt ttagacttcc gtttcccata acctttacgc aaatgacatg
    15421 gtttgtcgtg tcactctttg cagtgatgat acttggcaac ttgccccctc tttccatgat
    15481 agagggagca tttctcaaat actttgggat tcctgtggct ttcacatggt ttatgtctac
    15541 aaaaactttt gatggtaaaa agccttatgg atttttgaag tctgtcattg cttatgcact
    15601 gcgaccaaag ctgacctatg caggaaaaaa agtaacgctt ggcagaaacc agccacaaga
    15661 agccattaca gcagttagga gtgaatttta tggcatatcc aattaaatac attgaaaaca
    15721 atctcgtctg gaataaagac ggggaatgtt atgcttacta tgagcttgtt ccttacaatt
    15781 actcatttct aagtccagaa cagaaaatac aagtgcatga ttctttcaga cagcttatcg
    15841 cacaaaatcg tgatggcaaa attcatgctt tacaaatcag tacagaatcc agcatacgtt
    15901 ctgcacaaga gcgttccaaa aatgaagtca ctggcaagct caaagcggtt gcctatgaca
    15961 aaatcgacca acagacagac gctttaatat ccatgattgg cgaaaatcaa gtgaactacc
    16021 gtttctttat cggctttaag ttgcttctca acgatcagga gttttctatg aaaagtctta
    16081 ccgttgaagc aaaaaatgct ttgtctgatt ttgtctatga tgtgaaccat aagctgatgg
    16141 gcgattttgt tagtatgagt aatgatgaaa tcctgcgttt tcagaagatg gaaaagctct
    16201 tagaaaataa aatctctcgt cgtttcaaaa tccgcaggtt agataaggac gacttcggct
    16261 atctgattga acacctttac ggacagacag gcactgccta tgaagagtat gagtaccatc
    16321 tatcaaagaa aaagctggat aatgaaacgc tgattaaata ctatgacttg attaagccta
    16381 ctcgctgttt ggtggaagaa aaacagcgat atttgaaaat ccagcaggaa gatgaaaccg
    16441 tctatgtagc ttactttacc attaacagca ttgtcggaga actggacttc ccgtcctctg
    16501 aaatcttcta ctaccagcaa cagcaattta cattcccgat tgatacgtca atgaatgtgg
    16561 aaattgtagc gaatcgtaaa gccctatcta ctgtccgcaa taaaaagaaa gaactgaaag
    16621 acttggataa ccacgcttgg caaagtgata atgaaaccag ctccaatgtg gcggaagctc
    16681 tggaaagtgt gaatgagctg gaaaccaatt tagaccaaag caaggaatct atgtacaagc
    16741 tgtcttatgt ggtaagggta tcagcaaatg atcttgacga actcaaacgt cgttgtaatg
    16801 aagtgaaaga tttttatgac gatttaagcg taaaactggt acgaccattt ggggatatgc
    16861 tcggcttaca tgaagaattt ttacctgcca gcaagcgtta tatgaatgat tatattcaat
    16921 acgtgacctc tgatttcctc gctggtttag gttttggtgc tactcaaatg ctgggggaaa
    16981 atgaggggat ttatgttggc tacagcttag atactggacg caatgtctat ctgaaacctg
    17041 ctcttgccag tcaaggggtt aagggttcag taaccaatgc gttagcgtcg gcttttgttg
    17101 gttcgctggg tggtggtaaa tcctttgcga ataaccttat cgtctattat gcggtgcttt
    17161 atggggcaca agcagtgatt gtagacccaa aagcagaacg tggcagatgg aaagaaacct
    17221 tgccagagat ttcccatgaa atcaatatcg tcactctgac ttctgatgag aaaaacaaag
    17281 gcttacttga cccttatgtg attatgaaaa atcccaaaga ttctgaatca ctggctattg
    17341 atattctgac attccttacg gggatttcct ctcgtgatgg ggaacgcttc ccaatcctta
    17401 gaaaagccat tcgtgcagta accaatagtg aagtacgagg gttgatgaaa gtgattgagg
    17461 aattacgggt tgagaatacg ccactaagta ccagtatagc cgaccatatc gaaagtttta
    17521 cagactatga ctttgcacat ttattattca gtaatggtta tgtggagcag tctatcagct
    17581 tagaaaaaca actgaacatt atacaggttg cggacttggt acttcccgac aaggaaactt
    17641 cctttgagga atataccact atggagcttt tatccgttgc tatgctgatt gtcattagta
    17701 cctttgcttt agactttatc catacagacc gaagcatttt caagattgta gatttagacg
    17761 aagcatggag ctttttacag gtagcacaag gaaaaacact atctatgaag ctggttcggg
    17821 ctggtcgtgc tatgaacgct ggggtatatt tcgtgaccca aaatacagac gacctcttag
    17881 atgaaaaact gaaaaataac ctcggcttaa aatttgcatt tcgttccact gaccttaacg
    17941 agattaaaaa gaccttagcc ttttttggtg tagacccaga ggacgaaaac aatcagaagc
    18001 gattgcgtga tttggaaaac gggcaatgcc ttatcagtga tttatatggt cgtgtcggtg
    18061 tgatacagtt ccaccctgta tttgaagaac tgctccatgc ctttgatacc agaccacctg
    18121 tgcgaaaaga ggtgtaaatg tgaaaccatc aatagtaaac agaataaaat caaactggac
    18181 gctgaaacgt ctaggtaaag tggcaatgac agtggctttc acacttgtga ttgccatttt
    18241 tcttttagcc atgctgggaa cggtggttca agctgcgggc ttggtagatg atacggtcaa
    18301 tgtggcaaat gaatacagcc gatacccact tgaaaactat caactggatt tttatgtgga
    18361 taatagctgg ggctggcttc cgtggaactg gtcggacggg attggaaaac aggtcatgta
    18421 tggactatat gccattacca attttatttg gacaatcagt ttgtatgttt ccaatgcgac
    18481 aggttactta gtacaggaag cctattcctt agacttcatt tccgctacag cagattccat
    18541 tggtaagaat atgcagacct tagctggtgt gagtgcaaac ggattttcaa cagagggttt
    18601 ctatgttgga ttcctcttac tcttgatttt ggttcttggg gtttatgttg cctatacggg
    18661 actgataaag agagaaacca caaaggcaat tcatgccatt atgaattttg tgctggtgtt
    18721 tatcctatcg gcttccttta ttgcctacgc tcccgactac attaaaaaaa tcaatgactt
    18781 ttcatcagac atcagtaatg ccagtttatc acttggcacg aagattgtca tgccccattc
    18841 cgatagtcaa ggcaaggaca gcgtggactt aatcagagat agcctgtttt ccatacaggt
    18901 tcagcaaccg tggctactgc ttcaatacaa cagttcagac attgaaagta tcggtattga
    18961 ccgtgtggaa agcctgctct ccaccagccc agattccaac aatggcgaag acagagaaaa
    19021 aattgttgcg gaagaaattg aagacagaag caataccaat ctaaccatta caaagaccat
    19081 taaccgttta ggtacagtct tcttcctatt tgtcttcaat attgggattt ccatatttgt
    19141 attcctatta acaggaatca tgattttctc gcaggtactt tttatcatct atgctatgtt
    19201 tctgcctgtg agctttattt taagcatgat tccatcattt gatggtatgt caaaacgagc
    19261 cataacaaag ctctttaata ccattttgac acgagctgga atcacattga ttattacgac
    19321 agcatttagt atttcaacca tgctctatac cttatcggct ggttatccgt tctttttgat
    19381 tgcttttcta cagattgtga cctttgcagg aatctacttc aagctgggcg atttaatgag
    19441 tatgttttct ctacagagta acgattctca aagtgtggga agtcgtgtga tgagaaaacc
    19501 tcgtatgctt atgcacgctc acatgcaccg tctacagcgg aaacttggac gttccatgac
    19561 tactctaggg gctgggtctg ccattgttac aggtaaaaaa ggacagtcgg gttcggggag
    19621 ttctgcaagg acacaagcag atcactcccg accagacgga aaggaaaaat caacacttgg
    19681 aaaacgtatc ggtcaaacca tcggtacagt agctgatacc aaagacagaa tggtagacac
    19741 tgctagtggt ttgaaagaac aggttaaaga tttgccgacc aatgcaagat atgcagtata
    19801 tcaaggaaaa tccaaagtaa aagagaatgt ccgtgattta accagtagta tttctcaaac
    19861 caaagcggac agagccagtg gacgcaagga acagcaggaa caaaggcgaa aaaccattgc
    19921 gaagcgtcgc tctgaaatgg aacaggtcaa acagaaaaaa cagcctgctt cttctgttca
    19981 tgaaagaccg actacaagac aagaacaata tcatgatgaa cagacctcaa aacagtctaa
    20041 tattcagact tcatataagg aatctcaaca agccaaacaa gagcgtccag cagttaagtc
    20101 cgatttttca agtccaaaag tggaacgcca aggcaatacc gttcaagaaa aaaccgttca
    20161 aaagccagca acttcaacca ctacagcaga tagaacttca caacgtccaa tcacaaaaga
    20221 acgtccgtct actgttcaaa gagtaccact acaaaataca agaagtagac caccaatcaa
    20281 aaccgccacc attaagaaag tcggtaagaa accatgaagt tgaaaacttt agtgattggt
    20341 ggttctggat tattcttgat ggtcttctca ctgcttctgt ttgttgccat tttattttca
    20401 gatgaacagg acagcggaat ttccaatatt cattatggag gtgtgaatgt ttccgcagaa
    20461 gtgctggctc ataagcctat ggtagaaaaa tatgccaaag aatatggcgt tgaagaatat
    20521 gtcaacatac ttcttgcgat tatacaggtg gaatcgggcg gtactgcgga agatgttatg
    20581 cagtcctcgg aatccctcgg tcttccacct aattcattga gtacagaaga atccattaag
    20641 caaggtgtga agtatttcag tgaattatta gccagtagcg aaaggctcag tgtagattta
    20701 gaatcggtta tccagtccta caattatggt ggtggtttct tagggtatgt ggctaatcgt
    20761 ggaaataaat atacctttga actggctcaa agtttctcaa aagagtattc aggtggcgaa
    20821 aaagtgtctt accccaatcc catagccata cctatcaatg ggggctggcg atacaactat
    20881 ggcaatatgt tttatgtgca actggtaacg cagtatcttg tcacaacaga gtttgatgat
    20941 gatacggtac aagccatcat ggacgaagca ctgaaatatg agggctggcg atacgtttac
    21001 ggtggagctt ccccgactac ttcttttgat tgtagcggac tgacacaatg gacgtatgga
    21061 aaagctggaa ttaacttacc acgaaccgca caacagcaat atgatgtgac ccagcatatc
    21121 ccactatcgg aagcacaagc tggcgatttg gttttctttc attctaccta taacgctggc
    21181 tcttatatta ctcatgttgg gatatacctt ggcaataacc gtatgtttca tgcaggcgac
    21241 ccaatcggtt atgccgactt aacaagcccc tactggcaac agcatttagt gggagcagga
    21301 cgaatcaaac aatgagaaag gaagatttaa tgatgaaatt tagaaaaaat cagaataaag
    21361 aaaaacagat accaaaggaa aagaaacctc gtgtctataa ggtcaatcct cataaaaagg
    21421 ttgtgattgc cttgtgggta cttttagggc ttagtttcag ctttgcgata ttcaagcact
    21481 ttacagctat agatactcat actattcacg aaacaactat catagaaaag gaatacgttg
    21541 atactcatca tgtagaaaat tttgtagaga actttgcgaa agtctactat tcatgggagc
    21601 aatccgataa gtccattgat aatcgaatgg aaagtctaaa aggctatctg acagatgaac
    21661 ttcaagctct caatgttgat acagtacgca aagatattcc tgtatcgtct tctgtaagag
    21721 gatttcagat atggacggta gagccaactg gcgacaatga gtttaatgta acctacagtg
    21781 tagaccagct cattacagag ggagaaaata caaagaccgt ccactctgct tatatagtga
    21841 gtgtctatgt agatggttct ggaaatatgg tactggttaa gaatccgacc attaccaaca
    21901 tacctaagaa atcaagttat aaaccaaaag ccattgaaag tgaggggacg gttgattcca
    21961 ttacaaccaa tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga
    22021 cagccagtga actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt
    22081 acatctttca agaactggta aatcctattc acaatcgtaa ggataatcaa gtcacggtat
    22141 cgctgacagt ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt
    22201 tggtacttga aaagaacggg agtaattgga agattgtaaa ataacaaata ttggtacatg
    22261 attacagata ctttgtaatc atgtactctt tttgataaaa aattggagat tcctttacaa
    22321 atatgctctt acgtgctatt atttaagtga ctatttaaaa ggagttaata aatatgcggc
    22381 aaggtattct taaataaact gtcaatttga tagcgggaac aaataattag atgtcctttt
    22441 ttaggagggc ttagtttttt gtacccagtt taagaatacc tttatcatgt gattctaaag
    22501 tatccagaga atatctgtat gctttgtata cctatggtta tgcataaaaa tcccagtgat
    22561 aaaagtattt atcactggga tttttatgcc cttttgggtt tttgaatgga ggaaaatcac
    22621 atgaaaatta ttaatattgg agttttagct catgttgatg caggaaaaac taccttaaca
    22681 gaaagcttat tatataacag tggagcgatt acagaattag gaagcgtgga caaaggtaca
    22741 acgaggacgg ataatacgct tttagaacgt cagagaggaa ttacaattca gacaggaata
    22801 acctcttttc agtgggaaaa tacgaaggtg aacatcatag acacgccagg acatatggat
    22861 ttcttagcag aagtatatcg ttcattatca gttttagatg gggcaattct actgatttct
    22921 gcaaaagatg gcgtacaagc acaaactcgt atattatttc atgcacttag gaaaatgggg
    22981 attcccacaa tcttttttat caataagatt gaccaaaatg gaattgattt atcaacggtt
    23041 tatcaggata ttaaagagaa actttctgcc gaaattgtaa tcaaacagaa ggtagaactg
    23101 tatcctaata tgtgtgtgac gaactttacc gaatctgaac aatgggatac ggtaatagag
    23161 ggaaacgatg accttttaga gaaatatatg tccggtaaat cattagaagc attggaactc
    23221 gaacaagagg aaagcataag atttcataat tgttccctgt tccctgttta tcacggaagt
    23281 gcaaaaaaca atatagggat tgataacctt atagaagtga ttacgaataa attttattca
    23341 tcaacacatc gaggtccgtc tgaactttgc ggaaatgttt tcaaaattga atatacaaaa
    23401 aaaagacaac gtcttgcata tatacgcctt tatagtggag tactacattt acgagattcg
    23461 gttagagtat cagaaaaaga aaaaataaaa gttacagaaa tgtatacttc aataaatggt
    23521 gaattatgta agattgatag agcttattct ggagaaattg ttattttgca aaatgagttt
    23581 ttgaagttaa atagtgttct tggagataca aaactattgc cacagagaaa aaagattgaa
    23641 aatccgcacc ctctactaca aacaactgtt gaaccgagta aacctgaaca gagagaaatg
    23701 ttgcttgatg cccttttgga aatctcagat agtgatccgc ttctacgata ttacgtggat
    23761 tctacgacac atgaaattat actttctttc ttagggaaag tacaaatgga agtgattagt
    23821 gcactgttgc aagaaaagta tcatgtggag atagaactaa aagagcctac agtcatttat
    23881 atggagagac cgttaaaaaa tgcagaatat accattcaca tcgaagtgcc gccaaatcct
    23941 ttctgggctt ccattggttt atctgtatca ccgcttccgt tgggaagtgg aatgcagtat
    24001 gagagctcgg tttctcttgg atacttaaat caatcatttc aaaatgcagt tatggaaggg
    24061 atacgctatg gttgcgaaca aggattatat ggttggaatg tgacggattg taaaatctgt
    24121 tttaagtatg gcttatacta tagccctgtt agtaccccag cagattttcg gatgcttgct
    24181 cctattgtat tggaacaagt cttaaaaaaa gctggaacag aattgttaga gccatatctt
    24241 agttttaaaa tttatgcgcc acaggaatat ctttcacgag catacaacga tgctcctaaa
    24301 tattgtgcga acatcgtaga cactcaattg aaaaataatg aggtcattct tagtggagaa
    24361 atccctgctc ggtgtattca agaatatcgt agtgatttaa ctttctttac aaatggacgt
    24421 agtgtttgtt taacagagtt aaaagggtac catgttacta ccggtgaacc tgtttgccag
    24481 ccccgtcgtc caaatagtcg gatagataaa gtacgatata tgttcaataa aataacttag
    24541 tgtattttat gttgttatat aaatatggtt tcttgttaaa taagatgaaa tattttttaa
    24601 taaagatttg aattaaagtg taaaggagga gatagttatt ataaactaca agtggatatt
    24661 gtgtcctgta tgtggaaata aaacacgatt aaagataagg gaagatactg aattaaaaaa
    24721 attccccctc tattgtccga aatgcagaca agaaaattta attgaaataa agcagttcaa
    24781 agtaactgtg attacagagc cagacgcaaa gacgcagagc cgataaaatg agattaatac
    24841 aatctcattt tatcggctct ttccgttatg tatggattct tttaattagt cttcgatgtt
    24901 tcttgcttcg ttgataccgc tggctaaaga ttccattaag gatagttctt tgtctgtaaa
    24961 gctatccatg tatttctcta tctgtaatcg tcgggtgctt tttaccaagt tattagcagg
    25021 taagaaaaat tcatcaacgg aaacatgaag taacgataca aggtcataaa gaacttgtat
    25081 gctggggtgt tgccctttat tttcaatatt agttaagtac cgtgggtcaa tttcaatcaa
    25141 tgctcccact tgttcacgag ttaaacctcg tttcaatcga gcttctttaa tggctaaacc
    25201 aaaggctcta aaatcatatt tatcttcttt tttacgcata gtagaccacc tctatacatt
    25261 ttattgttcc tactgaatta aaaacaggta tagaaaaacg tgttatatgg tttataggtt
    25321 tatatttaat aaaaagcact actaaacgcc aataaaaaaa accgttatat ggtagtgcta
    25381 tttacgctgt taaaatattg tatattactt ccaaatggcg gtttgttgga ggtcaacgtc
    25441 gccatgaagt acatcatata caataaattt ccttacattg ggttcttgtc aaaaaaagtc
    25501 gtctatctgc aatagataag tacgtccacc aatgtggttt tataaatcat atagatagaa
    25561 taacagaagc atgtaaacag agaaataaat ctgtttatat gcttttttgg ctattcagaa
    25621 cttttttaca aagtttattt atcagtaatg caacaaatcc ccctttcaca ttgggactaa
    25681 gagtgaaagg agataaacga gcaaggctca cttcctttcc tagacagaaa gggggtgaga
    25741 aacatgaaac catcttcttt tcagaccaca atagaaaatc agtttgacta tatctgtaaa
    25801 cgtgctatgg aagacgagcg aaagaattat atgctttatc tttcaaggat tgcaaagcgt
    25861 gaggtgtcct tttcggatgt tggcgattat cttgttagcc agtttgcgac aacagataac
    25921 tattcaactg actttcagat ttttacactc aatgggttat cagtaggcgt tgaaaatgat
    25981 ttgttgagtg aagcattacg tgagttgcca gacaagaaac gtgaaattct actgctgttt
    26041 tactttatgg acatgagcga ttcagaaatt gcagacctgt tgaaattgaa ccgttctact
    26101 gtctatcggc atagaaccag tggactagcc ttaattaaaa agtttatgga ggaatttgaa
    26161 gaatgaaaac acaatatcct atgattccct ttcctctcat tgtaaaggca acagatggcg
    26221 ataccgaagc gattaaccag attctacatc attacagagg gtacataacg aagcgttccc
    26281 tacgacttat gaaagatgaa tatggcaatc aaagtatggt cgttgatgaa gtcttacgtg
    26341 gaagaatgga aaccagactg attacaaaga ttttgtcatt tgaaattaag taatatcctc
    26401 tctcctttcg tggaagcgtg ctaaaccatt ccacgcttcc cgaacaggga ggtttgttat
    26461 tccaccaaag catattgagc tttcaatgtg ttttgatagg ctaacgagcc attgttcttt
    26521 gaaaactgaa taaaagtaat cgaatacgtt tcgataagaa aagagccaac ggaactaacc
    26581 gccatgacct atcttataaa gatagcgagc gattcatgtt agtgatccga gaagcaatct
    26641 ttagcaggat tgcctgcaac gacattctta tcgtgataat gatactccca tacagtcaat
    26701 agtccgagcg tgataaaacc gtcgcaggca atgagtatgg ctacatgaga accatgcagg
    26761 ggtggaactc ccgtgagctt tgctaaagct gttcgattgc tggtaaaaca acttttatga
    26821 aatccaaata agtgatttgg aaaggaggat tttatgaagc agactgacat tcctatttgg
    26881 gaacgttata ccctaaccat tgaagaagcg tcaaaatatt ttcgtattgg cgaaaacaag
    26941 ctacgacgct tggcagagga aaataaaaat gcaaattggc tgattatgaa tggcaatcgt
    27001 attcagatta aacgaaaaca atttgaaaaa attatagata cattggacgc aatctagcgt
    27061 cgccaaaggg tcttgtatat gataaaatag tattaagtcg tatcaaggct ctttccataa
    27121 aggaaaggag caaatgccat gtcagaaaaa agacgtgaca ataaaggtcg aatcttaaag
    27181 actggagaga gccaacgaaa agacggaaga tacttataca aatatataga ttcatttgga
    27241 gaaccgcaat ttgtttactc gtggaaactt gtggctacag accgagtacc agcaggaaag
    27301 cgtgattgta tctcacttag agagaaaatc gcagagttac agaaagacat tcatgatggt
    27361 attgatgttg taggaaagaa aatgacactc tgccagcttt acgcaaaaca gaacgctcaa
    27421 agaccaaagg ttagaaaaaa cactgaaact ggacgcaaat atcttatgga tattttgaag
    27481 aaagacaagt taggtgtaag aagtattgac agtattaagc catcagacgc taaagaatgg
    27541 gctattagaa tgagtgaaaa tggttatgct tatcaaacca tcaataacta caaacgttct
    27601 ttaaaggctt cattctatat tgctatacaa gatgattgtg ttcggaagaa tccatttgac
    27661 tttcaactga aagcagttct tgatgatgat actgtcccta agaccgtact aacagaagaa
    27721 caggaagaaa aactgttagc ctttgcaaaa gctgataaaa cctacagcaa aaattatgat
    27781 gaaattctga tactcttaaa aacaggtctt cgtatttcag agtttggtgg tttgacactt
    27841 ccagatttag attttgagaa tcgtcttgtc aatatagacc atcagctatt gagagatact
    27901 gaaattgggt actacattga aacaccaaag accaaaagtg gcgaacgtca agttcctatg
    27961 gttgaagaag cctatcaagc atttaagcga gtgttagcga atcgaaagaa tgataagcgt
    28021 gttgagattg atggatatag tgatttcctc tttcttaata gaaagaacta tccaaaagtg
    28081 gcaagtgatt acaacggcat gatgaaaggt cttgttaaga aatacaataa gtataacgag
    28141 gataaattgc cacacatcac tccacatagt ttgcgacata cattctgtac caactatgca
    28201 aatgcaggaa tgaatccaaa ggcattacag tacattatgg gacatgctaa tatagccatg
    28261 acgctgaact attacgcaca tgcaacattc gattctgcaa tggcagaaat gaaacgcttg
    28321 aataaagaga agcaacagga gcgtcttgtt gcttagtagt acaaatgaat ttactactta
    28381 tttaccactt ctgacagcta agacatgagg aaatatgcaa agaaacgtga agtatcttcc
    28441 tacagtaaaa atactcgaaa gcacatagaa taaggcttta cgagcattta agaaaatata
    28501 aaaagataat tagaaattta tactttgttt gattgaaaaa tagtgcaaaa agcgctacaa
    28561 tggtagatgg aaaatcttgt gaaaagcaca agttatacat atataccgga ggaaatcatg
    28621 tctttttctg atttaaagct gtttgccctt tcttctaata aagaattggc agaacgtgtg
    28681 gcgcaggaga ttgggataga gttggggaaa tcaagtgttc gccaattttc agatggagag
    28741 attcaggtca acattgaaga atcaatccgt gggaaacacg tctttatctt acaatcaact
    28801 agttcgcctg taaatgacaa tctgcttgaa attttgatta tggtagatgc tttgaagcgt
    28861 gcgagtgcag aatctgttaa tgttgtcatg ccttactatg ggtatgcacg tcaggataga
    28921 aaggcgagag cgcgtgagcc aatcacttca aaacttgtcg caaatatgct tgaagtagct
    28981 ggagtggatc gtttattgac catcgacttg catgctgcgc aaattcaagg attctttgat
    29041 attcctgtgg atcatttgat gggtgctcct ctgattgcag attattttga gcgtcgtggt
    29101 atggttggtt ctgactatgt ggttgtcagc ccggaccatg gaggggtgac tcgtgctcgt
    29161 aagttggcag aatttttgaa aacatctatc gctattattg ataaacgtcg tagcgttgat
    29221 aagatgaata ctagtgaagt tatgaacatc atcggtaagg ttgaaggcaa gacttgtatc
    29281 ttgattgatg atatgattga taccgctgga acgatttgtc atgcggcaga tgctcttgcg
    29341 gaagctggtg ctgttgaagt ctatgcaagc tgtacgcacc cagttctttc tggtcctgct
    29401 acggacaata tccaaaaatc agctattaag aaattggttg ttttggatac catctatctg
    29461 ccagaagagc gtttgattga taagattgag cagatttcaa tcgctcatct cctaggggat
    29521 gctatcgtac gtattcatga aaaacgacca ctttctccac ttttcgatat tgagaaaaaa
    29581 atttaatgac caagcctgag atgattctca ggttttttcg tcttttttcc gaataaatag
    29641 atagtagcgg tgaatctagt aaagctagat ttaaaactgt gatataataa aaagagaaga
    29701 aatatgactg tacgtcatca gaagtttcag cgaccatcat ttttgaacag tgatagcact
    29761 tgaatcgacg ctttctaagg agaattctag taggtatacc agtcgtttca agataaggaa
    29821 ttttagaagg tttttgaaag tcatatttct tcaattggtt tccgcactca gggcaagatg
    29881 gggcgtcgta gtccagtttg gcgatgattt ccttgtgtgt atccttattg atgatgttta
    29941 aaatctggac attagggtct ttaatgtcta gtaattttgt gataaaatgt aattgttcca
    30001 tatgattctt tctaatgagt tgttttgtcg cttttcatta taggtcatat gggacttttt
    30061 tttacacaaa ataggctcca taatatccat agtgggtaaa tcccctatgg atattatgga
    30121 gccattttac aacagtgcct caaattcaga tactgacata cctaattgct ggctggcaac
    30181 ctcagaagtc agaagacctt ggcgtactat gtctaggaag gcaaaaagtt tcctttctgc
    30241 ccttccttca actttcccac gctctagtcc ttgttcaagg ccttcagccc tagcagtttc
    30301 caaggcatag tcctgtgcta acaagacttg ttcttctcgc atatgtagtt gactaaacat
    30361 tttcctgtcc tcctcggacc agctcttgta gtccagcagt tgatttgctt gggtaatggc
    30421 tcgttgcggt tgctgggtaa agggcttgtt gccgaaaaac tccaaccatg gcttgcgaac
    30481 cttgtctttg ctggtttctc tgtatttttt aattccaaga atgccatctt aaccagatgg
    30541 ttttcctgtc cattgttggt aatcgccaat acctcacctg ttgtgtcttc gcgcatacta
    30601 aagctatgaa aagccaggtc atctgagaaa taattactat ccacgatagc aatgacgtaa
    30661 acaggagcga tgtgtttgta gatctagtga gtatcacctt ctcgctgacg aattttttca
    30721 agattttgat taacctgact gcacaggtaa gcccacaagt gattgatgaa aaaattctga
    30781 tgatggactt gaatctcaat aattacttga gtaccgttat ccaactccgc caagacgtct
    30841 atactggtat aaaaatcctg caccgagtaa ggcatggaga gtaatacgtg aatatcgctt
    30901 ccctccaaaa tggtcacatt ttttgctggc aagtccagca tatcgcgaat aaattgacaa
    30961 gtgatttctg gattgctgaa tattttctta gcaatcaaat cattagttgg gctgatgccc
    31021 ggatgtctga gaatcctcct attcctcctt ctatagtgag ttgaaataag atgtgaataa
    31081 ctctatcagg aaagtcaaat taatttatag aaa
//
LOCUS       DAVMCG010000022        28929 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVMCG010000022 DAVMCG010000000
VERSION     DAVMCG010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.023"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..916)
                     /locus_tag="VYP66_001212"
     CDS             complement(<1..916)
                     /locus_tag="VYP66_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1850766.1"
                     /translation="MTKKKNTGKILTVVVPSYNAENYLQETMPTILSAKNIERVELLI
                     VNDGSTDRTEEIARQFEREYEGIVRVISKENCGHGSAVNVGIENAVGNYFKVVDADDW
                     VNTNNLEDLIVFLSEVDVDQVLSPYDKIFVNYRGDIEREEECNEFSQVENEVIYSAEE
                     FYTRIKQTVGMHSITVKTSLLQENNIRLSEKMFYVDMEYIVYMLPYVKKVVLFDKSIY
                     RYRLGTETQSISMASYIKNRDMHKQVIYHLVDFYNQMRSSAVLRRITWKLILNLIRQQ
                     WIIYFNLSKKEGKNSECFEFDNWLIKEGR"
     gene            complement(913..1953)
                     /locus_tag="VYP66_001213"
     CDS             complement(913..1953)
                     /locus_tag="VYP66_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1850767.1"
                     /translation="MKVTIIGQIKNKRTGLGKAINDFRDYCCNRATRVTEIDITNNFN
                     FLSSLFQILISDTDVYYFTPAGSVAGNIRDSLFLFFMIMKRKKIVTHFHNSAFGNVMR
                     QHPTLMIINRILYSKVDLIILLGEKSKIMFQQLRILDEKFKIIRNGVDGYLFIEKNEL
                     NKKMSDLPINIIFFSNMIREKGYEILLEVAKKMVGDEKYHFYFSGKFQDNNLKTRFIN
                     EIYSMNNVTYLDGVYGSDKKKLLQKMHYFVLPSYYKDETLPISMLEAMANGLYIIVSD
                     VGVVSEVINKETASLIEMINEETADSIIEIINQTSNKLNELDFNVSKYKQELLNENIQ
                     ASIYQQLERIAN"
     gene            complement(1957..2763)
                     /locus_tag="VYP66_001214"
     CDS             complement(1957..2763)
                     /locus_tag="VYP66_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4422 domain-containing protein"
                     /protein_id="HEV1850768.1"
                     /translation="MERSRLIDVKIIVATHKEVKMPQDNSLYLPIHVGRDGKSDIGFI
                     GDNTGDNISSLNPYYCELTGLYWAWKNLDYNYLGLVHYRRYFTNKSQGYNENVNMDDL
                     ILSRANVEILLEKSDIIVPKKRKYYIETLYSHYAHTLNGEHLDLARKIIEQNSSEYLS
                     SFDKVMKQRSGYMFNMFIMKKELLDDYLPWLFSILDTMYEQMDLTDYTLFESRLFGRV
                     SELLFNVWLCQKGITPKEVPFMYMERVDLFEKGKSFLMAKFFGKKYGQSF"
     gene            complement(2750..4117)
                     /locus_tag="VYP66_001215"
     CDS             complement(2750..4117)
                     /locus_tag="VYP66_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1850769.1"
                     /translation="MNGKIVKPSLAIIQSFLVILLTYLLSAVREAEIVSTTAIALYIL
                     HYFVFYISVYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRTYPNFKGSKKILLLTATFRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLERNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGVTGLWQVSGRSEIKNFDEVVKLDVAYIDDWTIWKDIEILLKTVKVVLM
                     KDGAK"
     gene            complement(4132..4821)
                     /locus_tag="VYP66_001216"
     CDS             complement(4132..4821)
                     /locus_tag="VYP66_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1850770.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSANIAWAFARAGYKTLLIDGDIRNSVMLGVFKARNKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFTTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRNCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGIVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            complement(4831..5523)
                     /locus_tag="VYP66_001217"
     CDS             complement(4831..5523)
                     /locus_tag="VYP66_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1850771.1"
                     /translation="MKEQNTIEIDVFQLFKTLWKRKLMILIVALVTGAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGSYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVTVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDVEDVLKIP
                     LLGLVPDFDKIK"
     gene            complement(5532..6263)
                     /gene="cps4B"
                     /locus_tag="VYP66_001218"
     CDS             complement(5532..6263)
                     /gene="cps4B"
                     /locus_tag="VYP66_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HEV1850772.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDRGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVHIIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            complement(6265..7710)
                     /gene="cps4A"
                     /locus_tag="VYP66_001219"
     CDS             complement(6265..7710)
                     /gene="cps4A"
                     /locus_tag="VYP66_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEV1850773.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPAGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAILQKLTST
                     EALKNYSTIINSLQDSIQTNMPLETMINLVNAQLESGGNYKVNSQDLKGTGRTDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            7931..8456
                     /locus_tag="VYP66_001220"
                     /pseudo
     CDS             7931..8456
                     /locus_tag="VYP66_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8449..8616)
                     /locus_tag="VYP66_001221"
     CDS             complement(8449..8616)
                     /locus_tag="VYP66_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEV1850774.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(8781..10388)
                     /locus_tag="VYP66_001222"
     CDS             complement(8781..10388)
                     /locus_tag="VYP66_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1850775.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKELLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            10541..12025
                     /locus_tag="VYP66_001223"
     CDS             10541..12025
                     /locus_tag="VYP66_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1850776.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            12120..12602
                     /locus_tag="VYP66_001224"
     CDS             12120..12602
                     /locus_tag="VYP66_001224"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1850777.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(12898..15003)
                     /locus_tag="VYP66_001225"
     CDS             complement(12898..15003)
                     /locus_tag="VYP66_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1850778.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDHTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLNSFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(15612..16592)
                     /locus_tag="VYP66_001226"
     CDS             complement(15612..16592)
                     /locus_tag="VYP66_001226"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1850779.1"
                     /translation="MFISLSAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKIDFFFWGVGLLASLLTLAILYLM"
     gene            complement(16594..18846)
                     /gene="pbpX"
                     /locus_tag="VYP66_001227"
     CDS             complement(16594..18846)
                     /gene="pbpX"
                     /locus_tag="VYP66_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEV1850780.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRTMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(18850..19167)
                     /gene="ftsL"
                     /locus_tag="VYP66_001228"
     CDS             complement(18850..19167)
                     /gene="ftsL"
                     /locus_tag="VYP66_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1850781.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(19179..20129)
                     /gene="rsmH"
                     /locus_tag="VYP66_001229"
     CDS             complement(19179..20129)
                     /gene="rsmH"
                     /locus_tag="VYP66_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1850782.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVVRKIHK"
     gene            20295..20489
                     /locus_tag="VYP66_001230"
     CDS             20295..20489
                     /locus_tag="VYP66_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850783.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            20505..21047
                     /locus_tag="VYP66_001231"
     CDS             20505..21047
                     /locus_tag="VYP66_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1850784.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLRILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            21058..21300
                     /locus_tag="VYP66_001232"
     CDS             21058..21300
                     /locus_tag="VYP66_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850785.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            21311..21646
                     /locus_tag="VYP66_001233"
     CDS             21311..21646
                     /locus_tag="VYP66_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850786.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(21756..22757)
                     /locus_tag="VYP66_001234"
     CDS             complement(21756..22757)
                     /locus_tag="VYP66_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1850787.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANKRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(22817..24718)
                     /locus_tag="VYP66_001235"
     CDS             complement(22817..24718)
                     /locus_tag="VYP66_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1850788.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYIFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(24740..25033)
                     /locus_tag="VYP66_001236"
     CDS             complement(24740..25033)
                     /locus_tag="VYP66_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1850789.1"
                     /translation="MDTILFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVFLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(25033..25851)
                     /locus_tag="VYP66_001237"
     CDS             complement(25033..25851)
                     /locus_tag="VYP66_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1850790.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(25838..26617)
                     /locus_tag="VYP66_001238"
     CDS             complement(25838..26617)
                     /locus_tag="VYP66_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1850791.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(26632..27123)
                     /locus_tag="VYP66_001239"
     CDS             complement(26632..27123)
                     /locus_tag="VYP66_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1850792.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(27134..28324)
                     /locus_tag="VYP66_001240"
     CDS             complement(27134..28324)
                     /locus_tag="VYP66_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1850793.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(28336..28770)
                     /locus_tag="VYP66_001241"
     CDS             complement(28336..28770)
                     /locus_tag="VYP66_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1850794.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT         8582 a         6433 c         4942 g         8972 t
ORIGIN      
        1 tccgtccttc ttttattagc caattatcaa attcaaaaca ctcgctgttt ttcccctctt
       61 ttttagataa attaaaataa attatccatt gctgtcttat taaatttaaa atcaatttcc
      121 atgttattct ccttaaaaca gcgctagatc tcatttgatt ataaaaatca accaaatgat
      181 agatcacttg tttatgcata tcacgatttt taatataact cgccatacta atgctttgtg
      241 tctctgttcc tagacgatat ctatagatac ttttatcaaa taaaacaacc ttttttacat
      301 atggaagcat ataaacaata tattccatat ctacatagaa cattttttca gacagccgaa
      361 tattgttctc ttgcaaaaga ctcgttttca cagtaatgga atgcattcct accgtttgtt
      421 taattcgtgt atagaattct tctgcagaat agatcacctc gttctcaact tgcgaaaact
      481 cgttgcactc ttcttcacgc tctatatcac ctcgataatt cacaaaaatt ttatcatatg
      541 gtgataaaac ttgatccaca tccacctcag atagaaacac tatcaaatct tctaaattat
      601 tggtgttcac ccaatcatct gcatctacca ctttaaagta attaccaaca gcattctcaa
      661 tccccacatt tactgccgaa ccgtgaccac agttttcctt acttataact ctaacaattc
      721 cctcatattc tctctcgaat tgtcttgcta tttcttcggt tctgtctgta gaaccatcgt
      781 ttacaatcag taattctacc ctctctatat tcttagcaga aagtatcgtc ggcatcgtct
      841 cttgtaaata attttctgca ttatatgatg gtacaactac tgttaatatt tttccagtat
      901 tttttttctt cgtcaatttg ctatcctctc taattgctga taaattgatg cttgtatatt
      961 ttcatttaac aactcttgct tatattttga tacattaaaa tctaactcat taagtttatt
     1021 tgaagtctga ttaataattt ctatgatact gtctgctgtt tcttcgttta tcatttcaat
     1081 aagactagca gtttctttat taatcacctc tgacacaact cccacatcgc ttacaataat
     1141 atagagacca tttgccattg cttctaacat actgataggt aaagtttcat ctttataata
     1201 cgatggtaaa acaaagtaat gcattttttg caataacttt ttcttatcac taccatatac
     1261 accatctaaa tatgttacat tattcatact ataaatttca ttaataaacc tagtctttaa
     1321 attattatcc tgaaattttc cagaaaaata aaagtgatat ttctcatccc ccaccatctt
     1381 cttagcaact tctaataaaa tttcgtaacc tttttctcta atcatattac taaaaaaaat
     1441 aatatttatg ggtagatcgc tcattttttt atttaattca tttttttcaa taaataaata
     1501 tccatccaca ccattcctaa ttattttaaa tttttcgtct aaaattctta gttgttgaaa
     1561 cattattttc gatttctctc ccaataatat aatcaaatca actttagaat acaatattct
     1621 atttattatc attagagtcg gatgttgtct catcacattt ccaaaagcac tattatgaaa
     1681 atgggtcact atttttttcc ttttcattat cataaagaac aaaaacagtg aatccctaat
     1741 attaccagct actgaaccag ctggagtaaa ataataaaca tctgtatcag atattaaaat
     1801 ttgaaaaaga gagcttaaaa aattaaaatt atttgttata tctatttccg ttactcttgt
     1861 agcacgattg caacaataat ccctaaaatc attaatcgcc tttccaagac ctgttctctt
     1921 attttttatt tgtccaataa tagttacttt catatcctag aaactctgtc catacttctt
     1981 tccaaaaaat ttagccatta aaaaagattt tcctttttca aacaaatcca ctctctccat
     2041 gtacataaat ggtacctctt taggcgttat tcctttttga cataaccaaa cattaaacaa
     2101 caactcacta actcgcccga ataaacgtga ctcaaataaa gtatagtcag tcaagtccat
     2161 ctgttcgtac atagtatcca gaatagaaaa aagccacggt aaataatcat ctaatagttc
     2221 ttttttcatg ataaacatat tgaacatata accgcttctt tgtttcatca ctttatcaaa
     2281 ggatgaaaga tactctgaac tattttgctc aataattttc ctagcaagat ccagatgttc
     2341 tccgttaagg gtatgggcat aatgtgaata aagagtttca atataatact ttcgcttctt
     2401 tggaactatt atgtcagatt tctctaataa tatttcaaca ttagctcgag acaaaatgag
     2461 gtcatccata ttgacatttt cattataccc ttgagattta tttgtaaaat aacgacggta
     2521 atgaactaaa cctaagtaat tataatcaag attcttccat gcccaataaa gtcccgttaa
     2581 ctcacaataa tatggattta gagaggatat attatcgcca gtattatcac cgataaaacc
     2641 aatatctgat ttaccgtctc tcccaacatg tattggaagg taaagactat tgtcttgagg
     2701 cattttaacc tctttatgcg ttgccacaat gatttttaca tctatcaatc tacttcgctc
     2761 catccttcat caatactacc ttaactgtct tcaataaaat ttcaatatct ttccagattg
     2821 tccaatcatc tatataagcc acatctaatt tgacaacttc atcgaaattt ttgatttcac
     2881 ttcgtccact gacctgccat aagcctgtta caccaggttt aaaacttagc cgacgttttt
     2941 gttctggggt atagtgttca tactcatcca ctgttggtgg ccgtgtgcca accaaactca
     3001 tatctccctt tagaacatta taaaactgtg gtagctcgtc caagctagtc ttccgtataa
     3061 aacgaccaat tttcgtgata cgaggatcat cgtccacctt aaacattcca ccctgcatgg
     3121 tattttgttc catgagttct ctttttttcg cctcggcatc tacacacata gagcgaaact
     3181 tataaaaggt gaactgacga ccattttttc ctatacgcgt ctgagcaaaa atagcagagc
     3241 ccccatcctt tcgaatcaaa ggaaccagta caatactgac taaaccacat aatatcaacc
     3301 cgaccaatgc acccatgata tcaataatcc gcttagcaat tacatgacta gtcttataaa
     3361 atgttgtaga aaaagtcaca acgtttaatc ctgccatctc acgaatttgc ttgttacgtt
     3421 ccaaactacg atcaaaagca tttagattaa ctgttacatc aattcccatc gtttcaaact
     3481 gagagacaag ctctccaata ttgtattttt cactcggaag attgataaag acttcatcga
     3541 ccacctcatg agtcgcaaag tttactatct ccccctctgc tactaccttt aaacaatcat
     3601 gctgaaaatc tggtttatct aagacactga cggctaccaa ctccccaaca acctcatttg
     3661 attctattaa tctatccagt accttttcga cacgaaaagt tgctgtaagc aagaggatct
     3721 tcttacttcc tttaaagttg ggataagtcc gcttccaata ccacttgata aataggttta
     3781 gcacatagac taagagagca tgtaatgtga ggaagtaaat catgcctcgt ctggaaatac
     3841 taaatcgatc ctctaagaaa aaattagaaa tactaatcgc tagtgcaaag aataggatat
     3901 atttcaatgt ctggacaagt tcaatcaaat atcccctttt aaagaaatcc tgcccataaa
     3961 cactgatata aaagacaaaa taatggagga tataaagtgc aatagctgtt gttgaaacaa
     4021 tctccgcttc tctcacagca ctaagtagat aagtcaataa aataacaaga aaactctgga
     4081 ttatggccaa tgaaggcttt actatttttc cattcatctc tatcccccga cctatttttt
     4141 atttttcccg taatctccat aatttccata agaaccgtat ttgtctactg aagtatcgaa
     4201 tttattcaac acaattccca aaaacggctt tcctgtgtgt tccaactgtt cttttgcttt
     4261 ttgaatatcc cgacgattta tttcacctgc ctccgtcact aaaatagaag catcgcagtt
     4321 tcgcgtaata atagccgcat caatcacgac accaacagga gcagtatcta caatgatgta
     4381 gtcaaaatat ttacgcaagg tttcaagcat tgtagtgaaa ttcttacttt gaagaagagc
     4441 tgtcggattc ggtgacacag agccagcctg aattacaaag agattttcga tattggtatc
     4501 acaaagccct tgtgataagt ctgtagttcc tgataaaaat tctgtcaggc ctgtaatctt
     4561 attccttgct ttaaagacac ctaacataac agaattgcga atatctccat caatcagcag
     4621 cgttttgtaa cctgcacgcg caaaagccca agcgatattg gcggaagtcg ttgattttcc
     4681 ttctcctatt ttcacagaag tgatagaaaa tactttcaaa ccatctccac ttaactgtag
     4741 gttcgtgcac aaagcgttat aatattcctc tgcctttttt acagaatcca attttgcctg
     4801 tgagatttct aatgttggca taacttcctc ctattttatt ttgtcaaaat ctggaacgag
     4861 ccctaaaagt ggaattttca gtacatcttc aacatcttca ggacgtttca cacgggtgtc
     4921 cagcaactca atcaaaagaa cagcaattac tgttacgact gctcctccaa gaaaaccaaa
     4981 caaggaattg cgtcgaacat ttggagaaga gggagtcgta gctggtcgcg cttcttcaag
     5041 tgtcgttaca tcagatactc gcgttacagc gacgatcttt tctgcagcaa cttctcgtag
     5101 agaattagcg atacgactgg cttcctctgg ctgtttatcc ttgacagaga ttgagacgat
     5161 acgagtgtca gctggtacag tcacttgaac tttgctggct aacgtttttg ctggcatatc
     5221 caacttcaaa tttgtcgcta ctttttccaa tgcatcctgc gaaaggataa tctcacggta
     5281 gtcttttacc agataagatc ctgcctgcaa atcctgattt gtcagccccg gcttgtctcc
     5341 ttgattgcga ttcactacgt aaattcgcgt ggtactcgta tattctggct taacaataaa
     5401 agtgctatat gcaaaagccc ccgcacctgt cacaagtgcc actattaaaa tcattagctt
     5461 gcgtttccac aaggttttaa ataattgaaa tacatcgatt tctatcgtgt tttgttcttt
     5521 catcatttct cctaaattag ttgatccatt acaatttttc gaggattgtc tataaaaagt
     5581 tcctgagcct tcgcttctcc gtatttttgg gtaacaaggt catatgcttc tgccatatga
     5641 ggaggtctac cgtctagatt gtgcatatca cttgcaatga tatgaaccaa atcctgctct
     5701 aaaaaatact gagctctttt tttcatgaat ttataacgtt cgccaaaaag tttgggtttg
     5761 aggacatgtg aactatttac ttgcgtgtaa cagcccctat caatcagttc tcgaacgcgt
     5821 ttttcattat tttcaagagc atcatagcgc tcaatgtggg caatgactgg agtaattccc
     5881 aacatcaaga tcttgctcaa ggcgctatga atatcgcgat aaggagtgtt catactgaac
     5941 tctatcaagg cataacgact atcattgagg gtcggaatcc gctttttttc cagcttatcc
     6001 agaacatctg gtgtgtagta aatttcagcc ccataagcaa tgaccaagtc actcgccact
     6061 tccttagcta tttcccgaac ctgaagaaag ttttctgcta tcttctcttc cggagtttca
     6121 aacatgccct tgcgacggtg agaggtagag acaatggttc tcaccccctg cctgtaggat
     6181 tctgtcaaga gagccttgct ttcctctctt gacttgggac cgtcatctac atcaaaaacg
     6241 atatgcgaat ggatgtctat catttcatct accctccatc acatcctgta tagctgcttt
     6301 aactacagct aaactactat catctatttc catcacatag aggttactgt ctggcattgc
     6361 ataagaagga agatccgtcc gacctgtacc ttttaaatct tgagaattta ctttataatt
     6421 ccctccactt tctaactgag cattgaccaa atttatcata gtctcaagtg gcatatttgt
     6481 ttggatagaa tcttgcaagc tattaatgat cgtgctataa tttttcagtg cttcggttga
     6541 cgttaatttt tgaaggatag ccacaatcac cttttgttga ttgcgcccgc ggtcacgatc
     6601 gccatctgct agtgagtagc gctcacgaac aaaaccgaga gcctgttctg aatcaagatg
     6661 aacattgcct gcagggtaat actttccatt cgtatgggca gtaaattctt gatcattata
     6721 aacatcaatt ccacccaaca aatcaatcaa tttcaaaaac gaagtgaagt tcaatcgcac
     6781 atagtaattg atatccactc catagagatt ttctaaggtg tgaatggacg aatcaactcc
     6841 ataaatgccc gcatgggtta atttatcttt ttgattattt ccaccatctg cgattggtac
     6901 ataggcatca cgtggcgttg tggtcaagag gattttcttg gtatctcgat tgacagtcat
     6961 caggatattg acatctgatc gcgacactga actaataggg ccataggtgt caattccact
     7021 aacatagata ttgaaagact gattcttaga cgtcttagga gcttctactt ttttagtgaa
     7081 tcccttggta taaatctttt ttatcttcga tgcgtagtct ggatactctg actcgatgat
     7141 attttcaaag acactattta ggacaatggc cttagtctcc cctgcaatca aactcttgta
     7201 agctgccaag taagacgaac tctggttgac cgtcaaatcg gtattctgac ttgacttgat
     7261 atcagctagt agtttttgaa tattttcatt atcagtccca gtcggtgctg tcacactcgt
     7321 cagttgcgta acattttcga tctcactatc tgctaaaaca gcgacactga ttgaatattc
     7381 tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca acaaactgct gtactgcaaa
     7441 gagcgacaca gagctgacaa ggatagagaa cagcaacaga aaaatagtaa atttttcagc
     7501 ttttttatag ataatcaaga gtagccctac caaggcaact agtaggacta acgcagttac
     7561 cactagatta agatatctaa aagcaaggat attgtactta aagattaaga acaataaaaa
     7621 acaaactaac aataaataaa tagtcagcaa aactatatta acacttcgct tcactttctg
     7681 tgaacgtgat tttttaaaac gtctactcat gattaacacc tatacattga acatcatacg
     7741 attatatcac ttttttacgg taatgtctac atttttttac tatctgcatc tttaagtatc
     7801 ttagtagact tcccgcgaaa caaaaatata gtaaaatgaa ataagaacat gacaaatcga
     7861 tcaggacagt taaatcgatt tctaaaaatt ttttagaagc agaggtgtac tactctagtt
     7921 tcaatctaat tatgaacaag acccagaaaa agtagcctta tttcttaaga attttaatag
     7981 tttaaagcac ctagcacctg tttagattga tgaaacagga ttcgatactt attttcatcg
     8041 agaatatggt cgctcattaa aaggtcagtt aagaagaggc aaagtatctg gaagaagata
     8101 tcagaggatt tctttgattg caggtctaac aaatgaatgg tgagttaatc gctccaatga
     8161 cttacgaaga gacgatgacg agcgactttt ttgaagcttg gtttcagaaa tttctcttac
     8221 caacattaac cacaccatcg gttattatta tggataatgc aagattccat agaatgggga
     8281 agctagaact tttatgcgaa gagtttgggc ataaactttt acctcttcct ccctactcac
     8341 ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat
     8401 taccaagttg caataccttt tatgaggctc ttttgtcttg ttcttgtttc aattgactat
     8461 attatcagcg taatagtcta atagatagtt aaatgtagtt ggatttccac taaaggttga
     8521 tgagtaagtt tttgtatctg aacctgattg gtcgcaagca gctaaaagca aagcagatgt
     8581 aaaagtcagg cctgcactaa ggatacgctt ctttatgttc gtcttctttc tccttaatag
     8641 tgggaatttg taaagttaat tgaatttcga gaatgaaggt ttataaacct tggttataaa
     8701 aaacaaagga tttctgcctt ttatacagtc ctcccttgtt tttatacgat ttcaatttta
     8761 aatttttctg caaaaaatat ttatagtaat tccacacaga aagcatccca tggaactaag
     8821 atttgttttt caaagacttc ttgagctagg gtgttttcaa tcaagacaga tttgactttt
     8881 ccttctactg tcaagtcttg ctcttcattg gacaagttag ccacaactag gaagcgacgg
     8941 tcgccatcct tacgtatata agcaaagacc ttatcagccg tatcaagcaa ttcaaagtca
     9001 gctcgaatta gccaactatt ctccttgcga atttggacca gtttctgata ggtatagaaa
     9061 atagaatctg gatttgccag cgcttcttgg acgttgatca tctcgtaatt tggattaacc
     9121 gccaaccaag gttgacctgt tgagaaacca gcgtttttgc tctcgtccca ttgcataggg
     9181 gtacgggcat tgtcacgtcc aataacacgg atactgtcca tgatttcttc aatcggaaca
     9241 cctttttcaa gagcctcacg cgcatagttg agggattcaa tatcttctac ttgatccagt
     9301 gtttcaaacg gatagttggt catcccaatc tcctcacctt ggtagatata aggagttcct
     9361 ctcatgagat gaagtaagat tgcaaaggct ttggcagatt tttcgcggta ttcttggtca
     9421 tttccccaga ttgagacaat acgagggagg tcatggttgt tccagaagag ggaattccag
     9481 ccgtcctcaa ctcctaactc tgtctgccat ttgttgaaga tttcttttaa cttagcgata
     9541 ttcagctctt tttgatagtg ccatttaggc tgaccttctt gatactgaag accgatatgt
     9601 tcaaactgga agaccataga caattcttgc ccctttggat cagagtagag cttggcaatc
     9661 tctggcgttg ctccccaagt ctcccctact gtcaagagct ccttatctcc aaaggtcgcc
     9721 tgattcattt ccttgagata gggatggagc ataggaccat tattgactac cttctcgtca
     9781 ggaattttgc caatcatgtc aataacatcc atacggaaac caccaatacc tttatcaatc
     9841 cagaagttca tcatctcata aattttctgg cgaagttttt cattttccca gttgagatcc
     9901 ggctgtttct tgctgaaaaa gtggagatag tattgacctg acttttcatc gtattcccaa
     9961 gcagacccac taaagataga atctaggtca ttgggttcat cgcgccagat atagtagtct
    10021 cgctcagggc tgtcagtatt ttcacaggct tcgacaaacc aagcatgctc atccgaggta
    10081 tgattgacca ccaagtccat gatgatacgg atatcacgct tcttagcttc tgcaatcagc
    10141 tgatccatgt cctccatggt tccaaaaata gccgcaatcg cttgataatc agcaatatcg
    10201 tagccattat catccatagg gctgtcataa acgggagaaa gccaaatcgc tgtgattcct
    10261 aacttagcta gatagtccaa cttactggta atacctggca aatcaccaac tccatctcca
    10321 ttactatcca taaaactctt tggatagact tgatagacta cggcattatg ccaccatttt
    10381 tcttgcatct gtttacctca ttattttaat aatctatagt ctatgatagc actttttaaa
    10441 attttgtgca agcgtttgct taatcttttt aatttctttt ttagctccgt agtttcctaa
    10501 cttccaattt tttattataa tagagtccag aggtaaaaaa atgaaaaaac aagcttttag
    10561 ttctgaacaa tatttgaatt tacaacgcga ccatattttg gagcgcatta accaatttga
    10621 cggcaagctc tacttagagt ttggcggtaa aatgttagaa gatttccacg ctgctcgtgt
    10681 ccttcctggt tatgaacctg acaacaaaat caagctcttg caagaattga aagagcaggt
    10741 tgaggttgtg attgccatta atgctagcaa cattgaacat tccaaagcac gtggcgactt
    10801 aggcatttct tatgaccaag aagttcttcg tttgattgac aaattcaatg aattagggat
    10861 ttttgttggt tccgttgtca ttacacaata cgctggccaa cccgctgcag atgccttccg
    10921 caatcaactt gagaaaaacg gaattgattc ttatcttcat tatccaatca aaggatatcc
    10981 gacggatatg gatcacatca tttccccaga aggcatgggc aaaaacgact acatcaaaac
    11041 cagtcgcaac ttgattgtcg taaccgctcc tggacccggt tctggaaaat tggcaacgtg
    11101 tatgtccaat atgtaccacg accaaatcaa tggcatcaaa tctggctacg ctaaatttga
    11161 aaccttccct gtttggaatc ttccccttca tcatccagtt aacttggctt atgaagctgc
    11221 cacagctgac cttgatgatg tcaacatgat tgaccccttc catcttcaaa cctatggaga
    11281 aaccactgtc aactacaacc gtgatatcga aatcttccca gtgctcaagc gcatgttgga
    11341 acgtattctc ggaaaatcac catacgcttc accgacagat atgggtgtca acatggttgg
    11401 tttcgctatt acagatgacg aggccgctgt cgaagcttct aaacaagaaa tcatccgccg
    11461 ttactatcaa acagttcttg acttcaaagc tgaaaaagtt ggcgaagctg ccgtcaagaa
    11521 aattgagttg ctcatgaacg acctcggtat cacacctgca gaccgtaagg ttgctgtcgt
    11581 tgcgcgccaa aaagcagaag aaactggtgg accagcccta gcctttgaat tgccaaatgg
    11641 ggaaatcgtc actggtaaga actcagaact ctttggtcct acagccgctg ccttgatcaa
    11701 cgccatcaaa aaatcagctg acatcgctaa agaagtaaaa ctaatcgaac ctgaagttgt
    11761 taagccaatc caaggtctta aaatcgatca tctcggtagc cgcaatccac gccttcattc
    11821 aaatgaaatc ctgattgcac ttgctatcac agctacagaa aatcctgatg ctgcccgcgc
    11881 tatggaagaa ctcggcaacc tcaaaggaag cgaagcccac tcaaccatca tcttgactga
    11941 tgaagacaag aatgtccttc gtaaactggg tatcaacgta acctttgacc catactacca
    12001 atacgaccgc ttatatcgta agtaaagatt tcaacctctc cagcctcgga gaggttttct
    12061 ctctgtctca ggagcaacct ttatgatata atgagagaag aaaactgaaa ggatttacca
    12121 tgtcaaaaga agttattgtc gaaagttttg aacttgacca caccattgtc aaagcaccct
    12181 atgttcgctt gattggggaa gaaacaggac caaaaggaga catcatctcc aattatgata
    12241 ttcgcttggt gcaaccaaac gaagactcta tccctactgc cggccttcac actatcgagc
    12301 acctcttagc caaactcatc cgtacccgca ttgacggcat gattgactgt tcaccatttg
    12361 gttgccgcac aggcttccac atgattatgt ggggacgtca caccagtgct aaaatcgcag
    12421 ctgttatcaa ggattcgctc aaggaaatcg ctgaaactac tacttgggaa gatgtcccag
    12481 ggacaaccat cgaatcttgc ggaaactaca aggaccacag cctcttctct gctaaagaat
    12541 gggcaaaact catcttggaa caagggattt cagatgatgc ctttgaacgt catgtgattt
    12601 aaaatcgagt aggggataat ctctagcccc tctcacacca ccgcacgtgc cgttcggcat
    12661 acggctgttc aactaacttt taacgcatgc cgttcaaggt aataatccaa acacgaaacc
    12721 agtccacgtt tttcaaggac tggttttgat atagcacgtt taagtaccga cttctgagct
    12781 actatagtag attgaaacta gaatagtata tctctactac acgacatgcc cgtcgtacct
    12841 caaaaggaac cagttttttt cagctggctc cttctttttt atcctcaaaa ttctatctta
    12901 ggctttctca cgaataacca aaacgccatc ttccatatct gcttccagat gtttagcatc
    12961 taaatgatct aagtggaagt ctgtcacctt atcacgaatt tcttgttcaa ccacgcgacg
    13021 gagaggacga acccccatga cttcgtcgta accttcttct gtgatataat ctttagccgc
    13081 ttgactgact accaagtcaa tgtctttctt agccaaggtt tggttaactt cagccaacat
    13141 caaatctaca atcttagaaa ggtcttcctt agtcaagtgt gagaactcga tgactgcatt
    13201 aaagcggttg aggaattctg gacggaagaa ggagttcaaa cggtccatca attctggttt
    13261 atccgcatct tctgtcaagt tggcttcata gccaaatcca gcatttgagg tcgcaataat
    13321 gacagtgttc ttgaagttta ctgtatttcc ttgaccatct gtcaaacgac catcatctag
    13381 aacttggagg agaagggtaa taacttgagg gtcagccttt tcaatttcat ccaagagaat
    13441 gatagagtat ggattgcgac gaacacgttc tgttaaggta ttgctattgt catcataacc
    13501 cacatagcct gctgttgtac caattagctt agaaacagct gtgtggtcac tgtattcaga
    13561 catatccaaa cggataatcg catcctgggt tccaaacata tcgagtgcca attgcttagc
    13621 aagctccgtc ttaccaaccc cagtagaccc tacaaagagg aagctgccga ttgggcgatt
    13681 tccttcatca aaaccagcac ggttacgacg gatagcacga gctacaactt ctacggcctt
    13741 atcttgacca atcaccttgt cttgcaagcg atgagccata tctttcaaac gttcgatatc
    13801 tgaagctccc atttgcgata ctgggatacc tgtcattcgt tccacagatt cagccacatc
    13861 gttgacactt gcagtcactt tcatatcttc tgtgtggttt tcgattttct tttccaattc
    13921 tgcaatgcgt gttttatagt ttagagctgc ttcaaaatct tctgcttcaa ctgctttttc
    13981 ttgcttgtct ttttccgttt cgatttctcg ttcaacagca tgcacatctg ttactggatg
    14041 ttgagccgcc aagtgagcag ccgttacatc gacaaggtca atagccttat ctggcaagct
    14101 acgttgagga atgtattgaa cagaataatc caccgctgct ttcaagactt cgtctggcaa
    14161 gatgacattg tggtgttgtt gatagaggtc acgaatgcct tgaagaattt taaaagtatt
    14221 ctctgctgaa ggagcattga ccttcacttc gttgaaacga cgagcaagag cagcattctt
    14281 caagatggtg ttacggtatt cgtcttgagt tgttgcccca atcactgtca attctccacg
    14341 agagagagct ggcttgagaa tatccgcaag ccctttagaa ccactgtctc caccagtgct
    14401 accagcacca agaatttggt gaatttcatc aaagaagagg ataatattcc ctgcttcttt
    14461 cacttcattg actaagtttt gtacattttc ttcaaagcta ccacggtatt gagtaccagc
    14521 ctcaagacct gagatatcaa tagaaataat ttccttgttc ttgatagcag caggaacatc
    14581 tccgttcaca atggcttgcg ctagaccttc gacaactgct gtcttaccaa cacctgcatc
    14641 tccgaccaaa acaggattgt tcttggtgcg gcgtgagagg atttcagatg tttcttgaat
    14701 ttccttgttt cgtccgataa caggatccaa cttgccctca cgcgcttctg ctgtcaagtt
    14761 tcgacctagt tttgcaagga caccgtcttg tttcatacct gatgcctgtt gtggcatttg
    14821 cacatcagtt tctgcatttc ctggtaattg accagtcgca cgatagtgag caaattcctc
    14881 aggtgtgact tcgcgtccat taattaagta acggcgattt tcagaactat atcctcgcat
    14941 accacccatc aattggttaa ataaatcatc catgttatta aaattattaa agttgttatt
    15001 catattcttt acctcttttt gtttacttag ttatgattac tgatattgac tatctttgac
    15061 ctttgtttta aaaaatttag actagctaaa ccgctaccct acgtactatt tctggttttt
    15121 ctttttcaag caggagtaga ctatctttac ttctgaagat ttctagatga aacatagact
    15181 cacctctttc tattttactt taaataagtg ttctagtaag gctttcattt accttacgtt
    15241 cataatatac tacattggtc agaaaaggtc aagatttttg actttaactg accaatgttt
    15301 ttttacactc ttcgaaaacc tcttcaaacc acatcagctt cgccttgtct acaacctcaa
    15361 aaccgtgttt tgagctgact tcgtcagttc tatcaaccat ctcaaaactg tatattaaaa
    15421 tgaaataaga acaggacaaa ttgatcagga cagtcaaatc gatttctaac aatgttttag
    15481 aagtagaggt gtactatttt agtttcaata tactatattt tgagcagcct aaagttagct
    15541 ttctagtttg ttctttgatt ttcattgtgt atttaaacac aaaaacaccc tgaaacatca
    15601 gggtgccatt cttacatcaa atataaaatt gcgagggtca ggagacttgc tagaagccca
    15661 actccccaaa agaagaagtc aatcttccac tcgctccaag gatttccttt accagacaat
    15721 cccccaagct caaaatggtg atgtacaggc gtcatacgga aaatacgttt accacctgtc
    15781 agtttgaaat aactgacttg catcataaca gaagttgttt caaaaacata cacaattccg
    15841 ataatcaaga gagtccattc ttggtggaga gccatagaga tagctgccag catcccacct
    15901 agggccaaac ttcccacatc acccataaag accttggcag gcttatggtt aaagatgaag
    15961 aaaccgagca aaccaccaat catggcaaga atcactagaa gaatatccat ctgaccttgc
    16021 acataggcaa taactccata ggcagacaaa ctaatcacaa cggaaatact agctaaaccg
    16081 tcaacaccgt ctgtcaagtt tactgcgttt gaaaaaccga ctagccagaa aagagcgaag
    16141 aaaatataga aaaatcccaa atgaactgga taaccaaaga cagacaggat atcgccaccg
    16201 cgctcataga aaagatagaa gataactcca cctagaagct gaagagctaa tttttgctta
    16261 ggattaagcc cctcattgat tttacgaaag accttgagaa agtcatctaa aaatccgacc
    16321 aagccataca agaccaagat gaacaaaatc attcccacat tattgctgaa ttggctacta
    16381 aatagggcga aaaagaaagc aaccaaaaca gaagtaatca agaaaaccaa acctcccatt
    16441 gtaggagtcc cagcttttgc ctgatgctgt ttgacatctt catgcatctg ctggcctgta
    16501 atttgcgcct ttctataaaa ttggataaag gccggaattc ctactaaagt tagtaaaaat
    16561 gtcacaattc cagcactgag ggaaataaac atattagtct cctaaagtta atgtaatttt
    16621 tttaatgtcc ttgatagctg tgttagcacg aacatcttgc ttctgcacag tagagcccga
    16681 accttgaaat tcaagttcta tattgagcca cttagcaagg gtctcagcag tctcctttgt
    16741 ccaaccatac atatctggaa cttcctctac tttatcagat aagataagga cttgctggtt
    16801 cggggcaaga ttcttccctt cttcagcaga actgttttta atcttcgttc ctgttcccac
    16861 aacgatgggt tgtacaagat tgcgacgcaa ttcttctgct aaatcaccag gtgaaatatc
    16921 cttgacacta ggcataggat aaggactttg ttgacttact tgctccaaag ctttagctgt
    16981 tgtttgaaga ttgagagagt ctttcatagc tgaagcccgc tccaagatag gattggcaaa
    17041 ttctcccaac tgaatacctg aataatgttc aggttgttgg accgtcacat acaagataaa
    17101 atcaggattt tcagccggac tcatcgatac agccgagaaa atatagtcgg ttaccccgac
    17161 tagataacca ccatttttct cgtcagcaat ctgagccgta ccagacttga gggctacatt
    17221 ttgcccagga acagttacag ttggcttgcc tgtgctgtgg ttatacatgg ttccataaac
    17281 cggatccgtc cctaccaaaa ccatgttagt ccgagttaga ctagctgcat ctttagaaac
    17341 aggatttccc acaatttctt tttgagattt ccgagcagtt tgatcatttg gatcataaat
    17401 ggcactaata aatttaggct ccagcatgac accgtcatta gcaatagctg taaaggcacg
    17461 aatcatttgc gtctgggtca ctgaaatccc ttgtccaaat gagctttgcg caatgttgac
    17521 aatattatcc gcaggaagct gaccagcata ctcatccgtc aaaccgaaac gggtcggaac
    17581 tccaaattta aaacgattaa gataatcaag ccaggtagca tctcccatct tttgctcaag
    17641 gagggtcatc ccaacgttac ttgagtgtgc aaaaccttga gaaaaagtca tcgttctgcc
    17701 accagtcaat ccttcattaa cgtcccaatc tcgaatcgtg gcatctgcaa tttttaactc
    17761 actactatta aagacttctc ctcctggaaa ggtattatta tcaatagcag cagccaacat
    17821 catcactttc atagtggaac ctggctcata gttactttgg taaaggatat cacgccaaac
    17881 aaagtcctct gtaatgcctt cttttgtatc tgcatcaaag gtcggtcgtt gcgttgttgc
    17941 cagaatttcc cctgttttag cactgaccaa agtcgctgtc atgtactttc cttttacctt
    18001 ctcttgaaaa gcatccatct gggtttccat aaaggactgg agggggctgg aaatggttgt
    18061 ataaacatcc ttaccgtcca tcgttcgttg ggaaacttgt tctgttccgg gtacaatatt
    18121 acccagacga tccttttcat aggtaataat gccgtctgtc cctgcaagaa tactgttcaa
    18181 ggaactctcc attccagagg ttcccagcaa gctcttgctt ccatcttcat tttcatggag
    18241 ctgagctaga ccgataaaac tagaagcaaa ttgtccgttt gggtaactac gattgggact
    18301 ggttgtaaaa tcaatcccct tgacctctgc agcttccaat tcttttttga tagacatcat
    18361 attggcatag gtaatcccat ttccctttgc tccaaaggaa acttgcttga gattaggttg
    18421 cgagagttgc tctcttacat aggattcttc catgtccaga tacttatgaa agacctctgc
    18481 aaccttgtta aattgtgttt tttctacgta aagaatctta cccgttgctg acttatagtt
    18541 ctcatcaatg accgcataga cattatagga ggttgcatcc tcagcaatcg ggactccatt
    18601 tcggtcataa atagtcccac gtttggcagg aactgtacgg gtggtttgat gaaccttctt
    18661 agcttccttc gctaaatctg ttccaaagcg agtgcctgtc ccaataatga ccgcaaaatt
    18721 gactaaaaaa atggcaaaaa caaagacaga taataaactc agactttttc caactctgcg
    18781 tctgttttca gccggcgatt tccgattttt ggtcgcataa cggattactc tttttgtcca
    18841 cttcatatct tactccgcta ttctaatatt ttcattgttt aattgcaaat cgtgtgaatt
    18901 ggcaatttct ttcaaacgtt ctgcacgtaa tagttcattg acctcttgct tggcatcgtc
    18961 caattcggtc ttcttttcct ctatctgcgc attgattttt gtcaaatcat tctgcacttg
    19021 caagagcttg gtctgcataa aaataatact aatggctaca ataagagtgg ttacagcaat
    19081 ggaaaagtaa aaagcttttt ccacacgcga aaaccgttta agttgcatct gtagtatttg
    19141 acctgttttt tccatttttt ctgccatctt tttccctctt acttgtgaat ttttctgacc
    19201 acgcgcaact tggctgagtg cgagcggtta ttggcttcta actcttccgc acttggcaag
    19261 attggcttac gggacaccaa ttccatcttg ggcttgagat catctgggat gaaaggcaag
    19321 ccttttggaa cttcaactgt tgaagcttcc ttgaacaatt gcttggtcaa gcggtcttct
    19381 aaggaatgaa aggtaatcac tgaaattcta ccatccagag ccaacatatc catagcctgc
    19441 tggatggact catctgccgc ccccagttca tcattgactt caattcgaat agcctggaaa
    19501 atctgcttag caggatgacc cttcttcttg agttccttgg caggtttgac caacttgata
    19561 atctctgcta actcagtcgt tgtctcaatc ggcttcactt cacgcgcttg ctcaatctta
    19621 cgcgcaatct gtttagagaa tttatcctca ccgtatttga agaaaatacg aaccaaatca
    19681 tgatagtcat aatgattaac cacttcatag gctgtcagac tagcatcctg attcatccgc
    19741 atgtccagtg gcgcatcctt tttataagaa aaaccacgct cacgctggtc caattgagga
    19801 ctagacactc ccaagtcata acaaattcca tcaatttcct gaacaccagc ttcgcgcaaa
    19861 cgtgcctgta aatgacggaa gttatccttg ataaaggtca ccattccctt ctcaatgtaa
    19921 ggtgccaagc gtttttgcgc attgtcaatg gcattctgat cctggtcaaa ggcatagaga
    19981 tggccttttt cacttaattt acttaataag tactcgctat gtcctgctcc gcccaaagtc
    20041 gcatcaacgt agataccgtc aggctttacg tcaagcatat caatcgtttc gtggagtaag
    20101 accgttacat gatgaaattc ttttgtcata tcttatctat tttaccacaa atccgaccag
    20161 cttgcacttg tcagacaaat aggacaagga gactactatt tcttcaaaaa atatgtcaaa
    20221 aatacttgac actttatgtt taaaagacta taatatagtc aaatatatac gacataaatc
    20281 agaaaggaga acagatgaat cgtgtgaaag aatttcgcaa ggaattgggt atttcccagc
    20341 tcgaactcgc caaggatatc ggtgtctcga gacagactat caatatgatt gaaaacgaca
    20401 agtacaatcc aaccttggaa ctctgtctca atctcgcccg cagcctccaa actgacctca
    20461 acagtctctt ttgggaggaa gatttttaaa aaaggagcaa actcatgaaa aaagaaacct
    20521 tcactgaaaa actgatcaaa cgcacatacg gtatttctgg tccccttgac gaatacaaac
    20581 ggcgtgaggc cgatagtatt gggaaccaag tctttatcat cctcttttat ctgatgattt
    20641 tcggaaatct tattccactc cttctggcct ataaataccc tcaagaagtg gctctaatct
    20701 atcctcctct gattttagtg attgccctca tcgcttctgg ctatgtcacc taccaaatga
    20761 aaaaaacagg catcacagtc attgaaccag atatgctgaa tgagaaagaa agcaagcaac
    20821 tacactaccc aggtctgaaa gcaggtttgt tctttggtct atggatgttt tttataactc
    20881 ctcttctcag gatactcata gatgaaggtc aggactattt tcattctctt ctcactataa
    20941 gaaatggtgt atcaagtatt ctcggttcta ttttcttcgg agcgagcata cagttcctca
    21001 tctcccgtcg cattgcaaaa actaagaaaa atcaagatga ggattaggag gaaactcatg
    21061 aaaaaagaaa agaaacagtt acgttatcct ggtctgaaag caggttcgat ttatggaaca
    21121 gtgatatttt ttataattcc actcattgat accctaacaa gtgaaaatcc aaattttatc
    21181 agttctcttc taaatacaaa acatattttt aaaactatac tgggagcttt ctttttcgga
    21241 gtgatgatac atattgtcga ctcacttcgt attgcaagag ctaaaaaaga ccaggattag
    21301 gaggtgcctt atgaaatcac tagctagact actgatcatt catgttttta tcagtatttt
    21361 ccttttcttt gcccttattt caggagctgt ttctcataca gttttactac tcctactcct
    21421 ctttcttcct gcgctcaata aaggacttga gaaaatacaa tcaaaacgga tacctgtcct
    21481 caacgcagcc ctcttctttc tcctcatatc ctttccacaa cttttaacca accctgtcca
    21541 atggaaattt tcaatattcc tagtcgtaac catcatttca agtttggcct acttctataa
    21601 cttttatcaa gtagttaaag aagtagatca aaaacagttg atttaggagc ttgctcccat
    21661 aatttctcat ttcataggca aataatccca cctagcttgt tctaggtggg attattttat
    21721 ttcttaacag agattgcaag tcattttcct tcattttaga aagtcgactc tttccaattc
    21781 acactacaat ccaagacttg ttgcctttct tcttgattgc ggccttcaat ctggtcaatc
    21841 aaaatctttg tagcctgttg tccttcctca aaggagggct gaaccagcgt cgaaacactt
    21901 ggagaagaaa agcaagtcca ctccgtattg tcaaaaccaa tcaacccaac ttgcggcaag
    21961 ttataattca actctttgat aacggtaaag actagaggta gggcccaaca gttagggata
    22021 aataccagag ttttttcatc gggatcgatt tctttttgta aaaattcctt aatttgttcc
    22081 aaattcgtat gcttatcttc aatggttaga ctggcgtgac gcttattagc atctgttaaa
    22141 gcatccacaa aaccacttgc ccgctcaatc cgagtactca aacgactcgt atccgctgta
    22201 atcaagagaa aatgttcata acctttttcg atacaggact gggtcatgtc ataaacggca
    22261 tcatagttat tggttttaac ccagctagtc cggtgttcat agagctgact atcaaaaaag
    22321 accattttct tctttttctc atcgatgata cgagaatatt ttcggaaatt agaggtcggc
    22381 tgaataataa agccgtctac tcccaagaga agcatgcttt caatataccg gtcctcactc
    22441 tcttggctgt aattactatt tcctatcatt acctggtagc cattctggct ggcgatatcc
    22501 tcaattccct taacaatttg gtttgagaaa ctgttggtaa tatcaccgat caaaacaccg
    22561 attaattttg ttcgtttgga gtttaagcta cgcgcaacaa tgctcggttt gtaatttgtt
    22621 tcatgaataa ctttttcaat cttttcacgt gtctcttggg acattttttc atatttcccg
    22681 tttaggtaaa atgacacggt tgttttcgag gtctgagcca tttccgcaat gtcttttatg
    22741 gtcagtttct tctccaatct aaaacacctc ctactaatac ttattataac atattcacta
    22801 ttcaaaatgc ctatttctag cactgcaagc gaatcattct ctcatttatt ttatcatata
    22861 ctagacattt tccacgcatt tttgttccgt caacgaggca caatttttca cctacaccaa
    22921 tatcctcgct taataacaga atcagcttgt ctgtttcgtc atttttcact tcaaaagcca
    22981 gagcattttc cacttcacga tcatctgtct ggtagacaga atgacggatg atttcaaaac
    23041 tctcatgcgc aatgatggta taatccagca tctgattctc aaagaattgg cgcttggtga
    23101 gtttgctact tctttcaagc tcattgtatt taggagaaat gatggtatct tccaaatcaa
    23161 aatcaacttc actccatagt ctcaactgat tgattttccc atcttgatag gtcacatcct
    23221 tgtcaaggat aaactgagtc aacgcctcat gctgaccttg acacctgatg tcatctacca
    23281 agagccagac atcctctacc aacatgagga tttttctctt gtgaagataa ggcaaatcag
    23341 gttctgctga ccaataagcc ccctcaatat aatgcactcc ctccctttct ttatggtgac
    23401 aaaacaggga gtgaggatag tattcatatt cccaggatcc cgtgattctt tccggagctt
    23461 tcccatctac aatgcaggtc gaatgactcc aagcactctt taagagataa cgttcatata
    23521 tctcccgata agaataacgc ccagcatcta tgaaaatagg ttggccttga tactgtaagc
    23581 aaaaactatt ctcgtcacta tggctatggg cacttcctag cggaccattt ttgaaaaata
    23641 tataacgatg ttcatcctta atgcagacat gtccagagtc ttcaaagatc atggacttag
    23701 gctgccaagc tctcctttca aattcctgca gtcgcttgac cttttctcgc cccaggaaca
    23761 agaggctaag taaatcgact ttaacatcca gaccgttaag aaggtcttcc ttgttcaaaa
    23821 ccacagcaga caggctcaac atttctgtcg tttctgtaga atcgctatca ccaaaagcca
    23881 aagtccgtcc atctaagcct gtcatcattt gaatataggt cgccatcttt tccagcaact
    23941 ctcggtaact atcttgcaag tctggaagca agagacacaa atccagcaag gctttataaa
    24001 cctctacatg atagagaatc gactgttcaa actggcttcc atctcctaaa atctgtgtct
    24061 caatttgctg tttcaactcc tctgaagcaa aatggtaagc ttcttctagg tccatcttat
    24121 ctgaaaagaa ataatagata gcaagcatcg gaattgtttg taaaatcccc cagttactaa
    24181 gggtgtactt ggcgcgatag tggcttttca taaagtcaat ctgcttttct agactgacca
    24241 aaattttctc tagttctttc tcctctagca agtcaaattt caagaggagc aagagtagtt
    24301 tcaaccaagt aaaggaacga atacccgtat ccaaggttct agtcatcaag gattgaggag
    24361 aaaattctct cacctgctca atccaatcaa atagaaagaa cttgcacttt tgaatatagt
    24421 ccttatctcc ttctaccaca taccctatca taaactgcaa gagatattct tgtcgattga
    24481 gcatataagc ccattctgga tcatcttcaa atacttgatc ccataccatc ggctggattt
    24541 gatggatttt tgaacaaggc tccatatccc aaggactatc aaacataaaa cgattgtcca
    24601 tcaagcgttc aagggaactc ttgactttct catagtcttt tgaacagtgg gacaagatat
    24661 aatcacgaca ttggtttcca tcgattcttt caaaaaattg tcttctttct tctttcatta
    24721 tctattacca gaaaaagaac tacttaaaaa gcagttcttt tgtctttccc attacacttt
    24781 ccttttctac atagatgacc acaccttttg caatctgcaa gaagaccaag tcatcttgga
    24841 tagaaatgat ttttccatga attccagaca ataacaacac ttcatcacca gatgttaaag
    24901 aagctaaata ctcttgtcgt tgctccatct gtttgcgaag caacttttgc tgacgaatag
    24961 aatgaaagct tgacagtaaa aggggactca ctgccaagac aatcactatt ccataaaaca
    25021 atattgtatc cattaagcta taatcttaag ccagcttccg ataattccga tgataactgt
    25081 taaaataacg agtttatatg ttgtccattt cttttctttg atcaagtagt aaactaaaag
    25141 tgtaaatagg gctggtagaa gagctggagc aaccttatca agcattccct gaatacttac
    25201 gatactttgt ttagcgtctg ctttaacttc ccctgcagca aaggtaatcg gcaccataat
    25261 cttaacagat gtcgctgcca aaccagcaat tacggttaca ccgataatat tggcaatacg
    25321 agaaatcgtt gccatctgtt cgcttagttt atcaatcaca gttgttccta gtttgtatcc
    25381 atacagacca gttgacaatt taatcgctgt taaaatcgta ttcatcgcaa ggaagaacaa
    25441 gattggaccg acaaccaagc cttcttgagc aaacgaagct gcgatggttg agaacaatgg
    25501 agctaaacag aattgagaaa gagaatcccc aatacctgcc aatggtccca tcaaggccat
    25561 cttgatgcta cgtgtttctt ttgccggacg gccattttcc aacattacaa gatgcaagct
    25621 ggtaataaaa ggcaggaagt gtgggttggt attatagaat tcacagtttt cttccaaggc
    25681 ttggtagaaa ccttcctgat cctctccata gtgttttttc aaagcaggat acatcacatt
    25741 ggcatatccc aacccttgat agttactata gttaaatcca ttttgacaaa agaatgcccg
    25801 caaagacgtt ttaagataat cacgttttgt taatttgtta gatccagtca tcgtgtgctt
    25861 cctcctctac cacatgatcc gctgtttttg gcttgttata aaattcaatc aaagcaaaga
    25921 tagtacctac aattgcaata ccaattgttg ggatgtttag ataagctgca caaacatatc
    25981 ccaacaagac aaagggaatc aactctttct tagccatcac tgacaagatc atcgcaaaac
    26041 cgatagctgg gagcatttta ccagcaactg tcaaacctgt aagtaatacc ggtggaatgt
    26101 agtctacgag tttcaacaag gtatccattg aaagggcacc caagcaaccc aaggtaaatc
    26161 caataaaggc aaacaaccaa attgttgcat ttagagtgaa cttgaatttc ttcaaattat
    26221 ggtttttcaa gtgcttcatc gccgtttcag gcgcaccagc acgtacagtg taggcgaaag
    26281 tttgtaagaa ttgaatcgcc acagcaatcg gagtagagag ggcaagagcc gcttctggac
    26341 tgactttacc agcactagtg atagccatca aggtaccaaa gataccaggt ccgattgggt
    26401 ttggtggaac agtacctcca gcaccaacac cgaatcccat ataagccaat tcaccaatag
    26461 ctcccattgc aagagcagta ggcagatcac ctagaataat tccgacacca aatgacagaa
    26521 caatacatct attggtgtaa attcctaaca gcattccact aaaacagaaa gctgtccata
    26581 atccaattaa aatcgcttga aatacattaa tcgacataac gatctcctct tttaaatata
    26641 gtccataatg ttgacttgaa cagctccatc atttcctgtt ggagttgttt tcgtattaaa
    26701 tgttacttga tgagtttggc tcaattcctt gagggctgcc ttgtcctctt cacccaggaa
    26761 gatggagcgt gtcacttgct ctttaccagt agcattgtga atgttcccaa tattgatttc
    26821 tttgataggg acaccacctt ctaccaaggt taaagcgtcc tttacatcct ttacaacgat
    26881 aaagatcgtt tgagcaggat tagccttgtg aatgatatca atcacctttt gcaaagggaa
    26941 gaaacgcatg gcaactgagt ctggcacaac tgttttcata agagtttgtt gcatcttgtc
    27001 cgtgcttact tcatcattgg caacaatgac cgtattacaa cctaggtatt ttacccaaag
    27061 ttgtccttgt ccatgaatca accgttcatc gatacgggtc ataataatat ttggcattgt
    27121 catatttctc ctcctaccaa tataggttcc agtctttgta gaaacggata agggcttcta
    27181 ggtaatagta gtcaccccag atattgcctt catccactcc tttacctgaa tgccatgagt
    27241 acacaccgtg gaggagactt gtcccaccag gggtaaattg atcatttgca taatgttcga
    27301 tcaaggaacg aagcatggca tgcatagcat gtttataaat atctttgtca gcatccacct
    27361 ctgggagatg ttttagcatt tcatgaatcc cacagacggc gatagctgtt gctgaagaat
    27421 ctcgtgattg atcactacca tcattaaaaa tcaaatccca ataggacaca tgatcttttg
    27481 gcagacgatt caagaaataa ttggtcacac ccttaaacaa gtcaaagcag gactcgtctt
    27541 ttaagtgacg ataagtcaaa ggaataccat agactcccca tgactgacca cgtgcccagc
    27601 atgaatcatc actataccct tgtctcgtta cacctttaaa gggttgacct gtctcaggat
    27661 caaaatagaa ggtgtggaag gacgaagcgt catcacggat tacattatta gctgaagcat
    27721 agaaatggct ttctgcaata tcgtagtatt tttgatcacc tgtttcttga taagcaaaga
    27781 ataagagttg gatattgagc aagcagtcga taatcaaacg gtaatgctct ttcttgccca
    27841 agtctcccca agcttgaata aaaccacctt tttcttgata gcgttcaatc aacttatctg
    27901 cagctttcaa ggctgcttct ctagcctctc catctccatt tatcttatat tcagccatac
    27961 aagacggtgt gtacaagaag ccgagatcat ggtgagccaa ttctactctc ttattgacac
    28021 gatccaggaa agaaagaaca tttttatgag cgatgttttt aaatgcatcc tgttgactgt
    28081 attcataagc caaccacagt tctcctgtcc agaaaccatt ggtccattcc gtgttatcca
    28141 tgattggata gacattatca aaggtagctg gcgtcgggaa atcttccttg aaatagtcaa
    28201 ggttgagttc taactgccga ataaccttat cgattgcctg gccgacttct tctttcgtca
    28261 gaagtggtac ttctaagaag cgctcaggcg attttatttt ttcaatcgta acctttttta
    28321 tcattctttt gccctttaaa tacccgattc gaaatcttct tcctcttcct ctgcatccgt
    28381 tgaaaacaat tctttaccat ttacaactcc gccctgggcc gccactactg atttattaac
    28441 aacctcatca aagctatgag ccattctagc aaagactgct tccattaaca tggctaagtt
    28501 caaacccgag agaacattca ttgtcttggc tggattttct cccattatgg tagaagaaac
    28561 cttgaatggc gatcctccca agagatcact taggattaaa acttcttctt catttgaaat
    28621 tgcaagtaag attttttgct tgagttcatc tgctgacatt ccttccacaa agtcaatcgc
    28681 ctccacattt tcttgattgc ctgcaatcaa ttgtaaagaa ctataaatcc ctgtagcaaa
    28741 atgtccatgc cctacaagta caattttcat cttttctcct ttcttgttta ggtttaccgg
    28801 tttactttat attccccatt gtaatccttt atttttatct tgtcaatagt ttttttaaaa
    28861 aaatattagc gctttcatta tctttttaat cattttaata gacagaaatt tcaaaatatt
    28921 ccattttta
//
LOCUS       DAVMCG010000023        26537 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVMCG010000023 DAVMCG010000000
VERSION     DAVMCG010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.024"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..1097
                     /gene="lytB"
                     /locus_tag="VYP66_001242"
     CDS             <1..1097
                     /gene="lytB"
                     /locus_tag="VYP66_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1850795.1"
                     /translation="KEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAE
                     KEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKTTNENAAYYQVVPVTA
                     NVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFI
                     PYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLT
                     EATNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRS
                     KIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASG
                     MNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(1158..2813)
                     /gene="pavA"
                     /locus_tag="VYP66_001243"
     CDS             complement(1158..2813)
                     /gene="pavA"
                     /locus_tag="VYP66_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1850796.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKITSMKKS"
     gene            2918..3415
                     /gene="ybeY"
                     /locus_tag="VYP66_001244"
     CDS             2918..3415
                     /gene="ybeY"
                     /locus_tag="VYP66_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1850797.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAKKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3396..3791
                     /locus_tag="VYP66_001245"
     CDS             3396..3791
                     /locus_tag="VYP66_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1850798.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3808..4707
                     /gene="era"
                     /locus_tag="VYP66_001246"
     CDS             3808..4707
                     /gene="era"
                     /locus_tag="VYP66_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1850799.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4756..5580
                     /gene="mutM"
                     /locus_tag="VYP66_001247"
     CDS             4756..5580
                     /gene="mutM"
                     /locus_tag="VYP66_001247"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1850800.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5580..6185
                     /locus_tag="VYP66_001248"
     CDS             5580..6185
                     /locus_tag="VYP66_001248"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1850801.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFEQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            6172..7371
                     /locus_tag="VYP66_001249"
     CDS             6172..7371
                     /locus_tag="VYP66_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1850802.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7371..7520
                     /gene="rpmG"
                     /locus_tag="VYP66_001250"
     CDS             7371..7520
                     /gene="rpmG"
                     /locus_tag="VYP66_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1850803.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7560..7793
                     /gene="secG"
                     /locus_tag="VYP66_001251"
     CDS             7560..7793
                     /gene="secG"
                     /locus_tag="VYP66_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1850804.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7895..10249
                     /gene="rnr"
                     /locus_tag="VYP66_001252"
     CDS             7895..10249
                     /gene="rnr"
                     /locus_tag="VYP66_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1850805.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQTLGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10212..10679
                     /gene="smpB"
                     /locus_tag="VYP66_001253"
     CDS             10212..10679
                     /gene="smpB"
                     /locus_tag="VYP66_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1850806.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10695..11555
                     /gene="tehB"
                     /locus_tag="VYP66_001254"
     CDS             10695..11555
                     /gene="tehB"
                     /locus_tag="VYP66_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1850807.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11628..12581
                     /gene="coiA"
                     /locus_tag="VYP66_001255"
     CDS             11628..12581
                     /gene="coiA"
                     /locus_tag="VYP66_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1850808.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12600..14402
                     /gene="pepF"
                     /locus_tag="VYP66_001256"
     CDS             12600..14402
                     /gene="pepF"
                     /locus_tag="VYP66_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1850809.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALVVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14404..15117
                     /locus_tag="VYP66_001257"
     CDS             14404..15117
                     /locus_tag="VYP66_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1850810.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQRLFDATLDNSELTATLVPLG
                     DGILMLRKNVADVQLPDSE"
     gene            15184..16125
                     /gene="prsA"
                     /locus_tag="VYP66_001258"
     CDS             15184..16125
                     /gene="prsA"
                     /locus_tag="VYP66_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1850811.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16244..16585)
                     /locus_tag="VYP66_001259"
                     /pseudo
     CDS             complement(16244..16585)
                     /locus_tag="VYP66_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            16999..17094
                     /locus_tag="VYP66_001260"
                     /pseudo
     CDS             16999..17094
                     /locus_tag="VYP66_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17347..17967)
                     /locus_tag="VYP66_001261"
     CDS             complement(17347..17967)
                     /locus_tag="VYP66_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1850812.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTPNTWNDTSYQS"
     gene            complement(17967..18449)
                     /locus_tag="VYP66_001262"
     CDS             complement(17967..18449)
                     /locus_tag="VYP66_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1850813.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDQMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(18449..19291)
                     /locus_tag="VYP66_001263"
     CDS             complement(18449..19291)
                     /locus_tag="VYP66_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1850814.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSH
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(19386..20186)
                     /locus_tag="VYP66_001264"
     CDS             complement(19386..20186)
                     /locus_tag="VYP66_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1850815.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            20330..21709
                     /gene="glmU"
                     /locus_tag="VYP66_001265"
     CDS             20330..21709
                     /gene="glmU"
                     /locus_tag="VYP66_001265"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1850816.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGNNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            21719..22264
                     /locus_tag="VYP66_001266"
     CDS             21719..22264
                     /locus_tag="VYP66_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1850817.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            22276..22590
                     /locus_tag="VYP66_001267"
     CDS             22276..22590
                     /locus_tag="VYP66_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1850818.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            22607..23299
                     /locus_tag="VYP66_001268"
     CDS             22607..23299
                     /locus_tag="VYP66_001268"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1850819.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            23376..23867
                     /gene="rocS"
                     /locus_tag="VYP66_001269"
     CDS             23376..23867
                     /gene="rocS"
                     /locus_tag="VYP66_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1850820.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            23965..24555
                     /locus_tag="VYP66_001270"
     CDS             23965..24555
                     /locus_tag="VYP66_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1850821.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            24564..26327
                     /locus_tag="VYP66_001271"
     CDS             24564..26327
                     /locus_tag="VYP66_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1850822.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINFLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFEFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         8073 a         4815 c         5824 g         7825 t
ORIGIN      
        1 aaaaagaatg ggtctacgat tctcatagtc aagcttggta ctacttcaaa tccggtggtt
       61 acatgacagc caatgaatgg atttgggata aggaatcttg gttttacctc aagtctgatg
      121 gtaaaatggc tgaaaaagaa tgggtctacg attctcatag tcaagcctgg tactacttca
      181 aatctggtgg ctacatggcg aaaaatgaga cagtagatgg ttatcagctt ggaagcgatg
      241 gtaaatggct tggaggaaaa actacaaatg aaaatgctgc ttactatcaa gtagtgcctg
      301 ttacagccaa tgtttatgat tcagatggtg aaaagctttc ctatatatcg caaggtagtg
      361 tcgtatggct agataaggat agaaaaagtg atgacaagcg cttggctatt actatttctg
      421 gtttgtcagg ctatatgaaa acagaagatt tacaagcgct agatgctagt aaggacttta
      481 tcccttatta tgagagtgat ggccaccgtt tttatcacta tgtggctcag aatgctagta
      541 tcccagtagc ttctcatctt tctgatatgg aagtaggcaa gaaatattat tcggcagatg
      601 gcctgcattt tgatggtttt aagcttgaga atcccttcct tttcaaagat ttaacagagg
      661 ctacaaacta cagtgctgaa gaattggata aggtatttag tttgctaaac attaacaata
      721 gccttttgga gaacaagggc gctactttta aggaagccga agaacattac catatcaatg
      781 ctctttatct ccttgcccat agtgccctag aaagtaactg gggaagaagt aaaattgcca
      841 aagataagaa taatttcttt ggcattacag cctatgatac gaccccttac ctttctgcta
      901 agacatttga tgatgtggat aagggaattt taggtgcaac caagtggatt aaggaaaatt
      961 atatcgatag gggaagaact ttccttggaa acaaggcttc tggtatgaat gtggaatatg
     1021 cttcagaccc ttattggggc gaaaaaattg ctagtgtgat gatgaaaatc aatgagaagc
     1081 taggtggcaa agattagtac tataagtgaa tatgatttga gtgaatagta agttaaaaat
     1141 cctgatttca agtaaaatca ggattttttc atggatgtaa tttttttgga gtctggtgtg
     1201 acgcggaggg tcttttgtcc tgtgtaagtg acaaagccgg gttttccacc agttggttta
     1261 ttgagttttt tgacttcaat catatctacc tgcaccagat tcgacaggcg cccttgagag
     1321 aagtaggcag ctaactctgc tgcgtctgtc ttgactgcat cagatgggtc aagatttcct
     1381 gagatgacaa catggcttcc aggaatgtcc ttagcatgga accaaagttc ctccttgcgg
     1441 gccattttaa aggtcaattc ctcattttga agattgtttc gtccgacata gatgatggtt
     1501 ttgccatcgc ttgctagata ttgttctagt tttttgcgtt tctggatttt ctcccgttgt
     1561 cttctgcgga taaaacctgt ttgaatcaat tcttcacgga tttcagcgat ttcttccagt
     1621 ccagcttggt tgaggacggt ttctacactt tccagataga gaatagtggc tttggtttct
     1681 tcaatcaaat cagtcaagta tttgacagct tctttgagtt tctgataccg tttaaaatag
     1741 cgttgggcat tctggttggg agtcagagcc ttatcaagcg caatcatgat aggttggttg
     1801 gtatagtagt tgtctaggat aacctggtct tggtcgttag gcacttggtg gaggaaggtt
     1861 gtcagcaatt ctcctttttg acgaaattct tcagcgttgt ctgtcgccag taattctttt
     1921 tcctgttttt tgagtttgtg tcggtttttc tgaagttcat tttcaacacg acgaatcagt
     1981 tcactggcct gctgtttgac gcggtcgcgc tcagccttat ccttatagta ggtgtccaac
     2041 aaatcagaaa gatttgcaaa aggctctccc acctgatttg caaaaggaac tggactgaag
     2101 gaagtctcag tcaagcatgg cttggtttcc tgattgaaaa aatttcggaa agcggaaagt
     2161 ttttcactaa ccagtatcct ttccaattca tttgccgtat cgcgtcccag accttgaaag
     2221 aggctttgaa gattttttgc tgttagttct tgggtttgca ggatttcaaa gagcttttca
     2281 tccttgatag taaaaggatt gagagattct gtacttggcg gagcgatata ggtcgatcct
     2341 ggaagtaagg tgcggtagct attttgtgaa aagccgacgt gtttgataac ttcgaggatt
     2401 ttatgactgc ttttatcgac cagtagaata ttactgtgtt tccccataat ttcgataatc
     2461 aaggtagcct ggatatggtc tccaatctcg tttttattgg aaactgtcat ttccacaata
     2521 cggtcatttt ccacttgctc aatcgactca atcagggccc cctgcaaata ctttctcaaa
     2581 accatgataa aggtagaagg ttgggctgga ttttcaaaag tcgtttgggt cagctgaatg
     2641 cgtccaaaaa ctggatgggc agaaaggagc aggcgatggc tttggcgatt gctgcggatt
     2701 tgcaagacca actcttgttc aaaaggctga ttgattttct ggatgcgacc attcactaat
     2761 tcgcttcgca attcctcaac tatgtggtgt aaaaaaaatc cgtcaaatga catcgttctc
     2821 tccttgtgat tgtattccat agtattatat caaaaaggta gaataaaatc atggaaatgt
     2881 ggtataataa agccaagtaa agagaaacga gaagcacatg tatattgaaa tggtagatga
     2941 aactggtcaa gtttcaaaag aaatgttgca acaaacccaa gaaattttgg aatttgcagc
     3001 caaaaaatta ggaaaagaag acaaggagat ggcagtcact tttgtgacca atgagcgtag
     3061 tcatgaactt aatctggagt accgtgacac cgaccgtccg acagatgtca tcagccttga
     3121 gtataaacca gaattggaaa ttgcctttga cgaagaggat ttgcttgaaa atccagaatt
     3181 ggcagagatg atgtctgagt ttgatgccta tattggggaa ttgttcatct ctatcgataa
     3241 ggctcatgag caggccgaag aatatggtca cagctttgag cgtgagatgg gcttcttggc
     3301 agtacacggc tttttacata ttaacggcta tgatcactat actccggaag aagaagcgga
     3361 gatgttcggt ttacaagaag aaattttgac agcctatgga ctcacaagac aataaacgaa
     3421 aatggaaaaa tcgtgacctg atatccagtt tagaatttgc catcacaggg atttttactg
     3481 ctatcaagga agaacgcaat atgcgaaaac atgcagtgac ggctctagtg gtcatccttg
     3541 caggttttgg ttttcaggtg tcacgaatcg aatggctctt tctcctattg agcattttct
     3601 tggtggtagc ctttgaaatt atcaattctg ctattgaaaa tgtggtggat ttggccagtc
     3661 actatcactt ttccatgctg gctaaaaatg ccaaggatat ggcggctggc gcggtattag
     3721 tggtttctct ttttgcagcc ttaacaggcg cattgatttt tctcccacga atctgggatt
     3781 tattatttta aacagtaaga ggaaattatg acttttaaat caggctttgt agccatttta
     3841 ggacgtccca atgttgggaa gtcaaccttt ttaaatcacg ttatggggca aaagattgcc
     3901 atcatgagtg acaaggcgca gacaacgcgc aataaaatca tgggaattta cacgactgat
     3961 aaggagcaaa ttgtctttat cgacacacca gggattcaca aacctaaaac agctctcgga
     4021 gatttcatgg ttgagtctgc ctacagtacc cttcgcgaag tggacactgt tcttttcatg
     4081 gtgcctgctg atgaagcgcg tggtaagggg gacgatatga ttatcgagcg tctcaaggct
     4141 gccaaggttc ctgtgatttt ggtggtgaat aaaatcgata aggtccatcc agaccagctc
     4201 ttgtctcaga ttgatgactt ccgtaatcaa atggacttta aggaaattgt tccaatctca
     4261 gcccttcagg gaaataacgt gtctcgtcta gtggatattt tgagtgaaaa tctggatgaa
     4321 ggtttccaat atttcccgtc tgatcaaatc acagaccatc cagaacgttt cttggtttca
     4381 gaaatggttc gcgagaaagt cttgcactta actcgtgaag agattccgca ttctgtagca
     4441 gtagttgttg actctatgaa acgagacgaa gagacagaca aggttcacat ccgtgcaacc
     4501 atcatggtcg agcgcgatag ccaaaaaggg attatcatcg gtaaaggtgg cgctatgctt
     4561 aagaaaatcg gtagcatggc ccgtcgtgat atcgaactca tgctaggaga caaggtcttc
     4621 ctagaaacct gggtcaaggt caagaaaaac tggcgcgata aaaagctaga tttggctgac
     4681 tttggctata atgaaagaga atactaagta gaggtaggct catgcctgct tcttgttttt
     4741 acagaaggag gacttatgcc tgaattacct gaggttgaaa ccgtttgtcg tggcttagaa
     4801 aaattgatta taggaaagaa gatttcgagt atagaaattc gctaccccaa gatgattaag
     4861 acggatttgg aagagtttca aagggaattg cctagtcaga ttatcgagtc aatgggacgt
     4921 cgtggaaaat atttgctttt ttatctgaca gacaaggtct tgatttccca tttgcggatg
     4981 gagggcaagt atttttacta tccagaccaa ggacctgaac gcaagcatgc ccatgttttc
     5041 tttcattttg aagatggtgg cacgcttgtt tatgaggatg ttcgcaagtt tggaaccatg
     5101 gaactcttgg tgcctgacct tttagacgcc tactttattt ctaaaaaatt aggtcctgaa
     5161 ccaagcgaac aagactttga tttacaggtc tttcaatctg cccttgccaa gtccaaaaag
     5221 cctatcaaat cccatctcct agaccagacc ttggtagctg gacttgggaa tatctatgtg
     5281 gatgaggttc tctggcgagc tcaggttcat ccagctagac cttcccagac tttgacagca
     5341 gaagaagcga cagctattca tgaccaaacc attgctgttt tgagccaggc tgttgaaaaa
     5401 ggcggttcca ccattcggac ctataccaat gcctttgggg aagatggaag catgcaggat
     5461 tttcatcagg tctatgataa gactggtcaa ggatgtgtac gctgtggtac catcattgag
     5521 aaaattcaac taggcggacg aggcacccac ttttgtccaa actgtcaaag gagggactga
     5581 tgggaaaaat catcggaatc actgggggaa ttgcctctgg taagtcaact gtgacaaatt
     5641 ttctaagaca gcaaggcttt caagtagtgg atgccgacgc agtcgtccac caactacaga
     5701 aacctggtgg tcgtctgttt gaggctctag tacagcactt tgagcaagaa atcattcttg
     5761 aaaacggaga actcaatcgc cctctcctag ctagtctcat cttttcaaat cctgaagagc
     5821 aaaaatggtc gaagcaaatt caaggggaga ttatccgtga ggaactggct actttgagag
     5881 aacagttggc tcagacagaa gagattttct tcatggatat tcccctactt tttgagcagg
     5941 actacagcga ttggtttgct gagacttggt tggtctatgt ggaccgagat gcccaagtag
     6001 aacgcttaat gaaaagggac cagttgtcca aagatgaagc tgagtctcgt ctggcagccc
     6061 agtggccttt agaaaaaaag aaagatttgg ccagccaggt tcttgataat aatggcaatc
     6121 agaaccagct tcttaatcaa gtgcatatcc ttcttgaggg aggtaggcaa gatgacagag
     6181 attaactgga aggataatct gcgcattgcc tggtttggta attttctgac aggagccagt
     6241 atttctttgg ttgtaccttt tatgcccatc ttcgtggaaa atctaggtgt agggagtgag
     6301 caagtcgctt tttatgcagg cttagcaatt tctgtctctg ctatttccgc ggcgctcttt
     6361 tctcctattt ggggtattct tgctgacaaa tacggccgaa aacccatgat gattcgggca
     6421 ggtcttgcta tgactatcac tatgggaggc ttggcctttg tcccaaatat ctattggtta
     6481 atctttcttc gtttactaaa cggtgtattt gcaggttttg ttcctaatgc aacggcactg
     6541 atagccagtc aggttccaaa ggagaaatca ggctctgcct taggtacttt gtctacaggc
     6601 gtagttgcag gtactctaac tggtcccttt attggtggct ttatcgcaga attatttggc
     6661 attcgtacag ttttcttact ggttggtagt tttctatttt tagctgctat tttgactatt
     6721 tgctttatca aggaagattt tcaaccagta gccaaggaaa aggctattcc aacaaaggaa
     6781 ttatttacct cggttaaata tccctatctt ttgctcaatc tctttttaac cagttttgtc
     6841 atccaatttt cagctcaatc gatcggccct attttggctc tttatgtacg cgacttaggg
     6901 cagacagaga atcttctttt tgtctctggt ttgattgtgt ccagtatggg cttttccagt
     6961 atgatgagtg caggagtcat gggcaagcta ggtgacaagg tgggcaatca tcgtctcttg
     7021 gttgtcgccc agttttattc agtcatcatc tatctcctct gtgccaatgc ttctagcccc
     7081 cttcaactag gactctatcg tttcctcttt ggcttgggaa ccggtgcctt gattcccggg
     7141 gttaatgccc tactcagcaa aatgactccc aaagccggca tttcgagggt ctttgccttc
     7201 aatcaggtat tcttttatct gggaggtgtt gttggtccca tggcaggttc tgcagtagca
     7261 ggtcaatttg gctaccatgc tgtcttttat gcgacaagcc tttgtgttgc ctttagttgt
     7321 ctctttaacc tgattcaatt tcgaacatta ttaaaagtaa aggaaatcta gtgcgagtaa
     7381 aaattaatct caaatgctcc tcttgtgaca gtatcaatta cctaaccagt aaaaattcaa
     7441 aaacccatcc agacaagatt gaggttttaa agtattgtcc caaggaaaga aaagtaaccc
     7501 tacatcttga atctaagtag attttatggt aaaataatag ggattttaag gagtttgata
     7561 tgtataacct attattaacc attttattag tattatctgt tgtgattgtg attgcaattt
     7621 tcatgcaacc aaccaaaaac caatccagca atgtatttga tgccagttca ggtgatttgt
     7681 ttgaacgcag taaagctcgc ggttttgaag ctgtaatgca gcgtttgaca gggattttag
     7741 tctttttctg gctagccatt gccttagcat tgacggtatt atcaagtaga taagaaaata
     7801 atgggcagga ctaggtcttt gcctcttttt atttttaaag gatgtttgag aaggttttac
     7861 agtaaaagaa aattaaaaaa tctagaaaga aaatatgaaa gatagaataa aagaatattt
     7921 acaagacaag ggaaaggtga ctgttaatga tttggctcag actttgggaa aagacagttc
     7981 caaggatttt cgtgagttga ttaaaacctt gtccttaatg gaaagaaagc accagattcg
     8041 ctttgaagaa gatggtagtc tgacattaga aattaagaaa aaacatgaga ttaccctcaa
     8101 ggggattttt catgcccata aaaatggctt tggctttgtt agtctggaag gcgaggagga
     8161 cgaccttttt gtagggaaaa atgatgtcaa ctatgctatt gatggtgata ccgtcgaggt
     8221 agtgattaag aaagtcgctg accgcaataa gggaacagca gcagaagcca aaattattga
     8281 tatcctagaa cacagtttga caacagttgt cgggcaaatc gttctggatc aggaaaaacc
     8341 taagtatgct ggctatattc gttcaaaaaa tcagaaaatc agtcaaccga tttatgttaa
     8401 gaaaccagcc ctaaaattag aaggaacaga agttctcaaa gtctttatcg ataaataccc
     8461 aagcaagaaa catgatttct ttgtcgcgag tgttctcgat gtggtgggac actcaacgga
     8521 tgtcggaatt gatgttcttg aggttttgga atcaatggac attgtatccg agtttccaga
     8581 agctgttgtt aaggaagcag aaagtgtgcc tgatgctccg tctcaaaagg atatggaagg
     8641 tcgtctggat ctaagagatg aaattacctt taccattgac ggtgcggatg ccaaggactt
     8701 ggacgatgca gtgcatatca aggctctgaa aaatggcaat ctggagcttg gggttcacat
     8761 cgcagatgtt tcttattatg tgaccgaggg gtctgccctt gacaaggaag cccttaaccg
     8821 tgcgacttct gtttacgtga cagaccgagt ggtgccaatg cttccagaac gactatcaaa
     8881 tggcatctgc tctctcaatc cccaagttga ccgcctgacc cagtctgcta ttatggagat
     8941 tgataaacat ggtcgtgtgg tcaactatac cattacacaa acagttatca agaccagttt
     9001 tcgtatgacc tatagcgatg tcaatgatat cctagctggc gatgaagaaa agagaaaaaa
     9061 atatcataaa attgtaccaa gtatcgaact catggccaag cttcatgaaa ctttagaaaa
     9121 catgcgtgtg aaacgtggag ctctcaattt tgataccaat gaagcgaaga ttttagtgga
     9181 taaacaaggt aagcctgttg atatcgttct tcggcagcgt ggtattgccg agcggatgat
     9241 tgagtctttt atgttgatgg ctaatgaaac agttgccgaa catttcagca agttggattt
     9301 gccttttatc tatcgaattc acgaggagcc taaggctgaa aaggttcaga agtttattga
     9361 ttatgcttcg agttttggct tgcgcattta tgggactgcc agtgagatta gtcaggaggc
     9421 acttcaagac atcatgcgtg ctgttgaggg agaatcttat gcagatgtat tgtccatgat
     9481 gcttcttcgc tctatgcagc aggctcgtta ttcggagcac aatcacggcc actatggact
     9541 agctgctgac tattatactc actttaccag tccaattcgt cgttatccag accttcttgt
     9601 tcaccgtatg attcgggatt acggccgttc taaggaaata gcagagcatt ttgaacaagt
     9661 gattccagag attgcgaccc agtcttccaa ccgtgaacgt cgtgccatag aagctgaacg
     9721 tgaagtcgaa gccatgaaaa aggctgagta tatggaagaa tacgtgggtg aagagtatga
     9781 tgcagttgta tcaagtattg tcaaattcgg tctctttgtc gaattgccaa acacagttga
     9841 aggcttgatt cacatcacta atctacctga attttatcat ttcaatgagc gtgatttgac
     9901 tcttcgtgga gaaaaatcag gtatcacttt ccgagtgggt cagcagatcc gtatccgtgt
     9961 tgaaagagcg gataaaatga ctggagagat tgatttttca ttcgtaccta gtgagtttga
    10021 tgtgattgaa aaaggcttga aacagtctag tcgtagtggc agagggcgtg gttcaaatcg
    10081 tcgttcggat aagaaggaag acaagagaaa atcaggacgc tcaaatgata agcgtaagca
    10141 ttcacaaaaa gacaagaaga aaaaaggaaa gaaacctttt tacaaggaag tagctaagaa
    10201 aggagccaag catggcaaag ggcgagggaa aggtcgtcgc acaaaataaa aaggcacgcc
    10261 acgactatac aatcgtagat acgctagagg cagggatggt cctgactgga actgaaatca
    10321 agagtgtacg agctgctcga attaatctca aggatggctt tgctcaagtg aaaaatggag
    10381 aagtttggct gagcaatgtt catatcgcgc cttacgaaga gggcaatatc tggaaccagg
    10441 aaccagaacg tcgtcgtaaa ctcctgctcc ataaaaagca aattcaaaaa ttggaacaag
    10501 agaccaaagg gacaggaatg accttagttc cccttaaggt ctatataaaa gatggctacg
    10561 ctaagcttct tttaggactt gccaaaggga agcatgacta tgacaaacgg gagtctatca
    10621 aacgtcgtga gcaaaatcga gatatcgcgc gtgtgatgaa agctgttaat cagcgataaa
    10681 aagaggaatt gaaaatggaa aaattagttg cctataaacg catgcctttg tggaataaac
    10741 aaacaatgcc tgaagctgtt cagcaaaagc acaatacaaa agttgggact tgggggaaaa
    10801 ttactgtctt gaagggagct ctcaagttta ttgaattgac agaagaagga gaagttctag
    10861 ctgaacacct ctttgaagca ggggcagaca atccaatggc ccaacctcaa gcctggcacc
    10921 gagtggaagc tgccacagat gatgtggaat ggtacttgga attttattgt aagcctgagg
    10981 attattttgc taaaaaatac aataccaatc ctgttcattc agaggtccta gaggccatgc
    11041 agacagtgaa acaagggaaa gctttggatt tgggttgtgg tcaggggcgt aattctcttt
    11101 ttctagccca gcaagatttt gatgtgacgg ctgtagatca aaatggactg gctcttgaaa
    11161 tcttgcaaag cattgtggag caggaagatt tggacatgcc tgttggcctt tacgatatca
    11221 attcagctag cattggacaa gaatatgatt ttatcgtttc aacagttgtt ctcatgtttc
    11281 tacaagcgga ccgcattcca gctattattc aaaatatgca ggagaaaacc agtgttggtg
    11341 gttacaacct tatcgtttgt gccatggaca cggaggatta tccttgctcg gttaatttcc
    11401 cattcacctt taaagaagga gaactggcag actattacaa ggattgggaa ttggttaagt
    11461 acaatgaaaa tccaggccat ttgcaccgtc gcgatgagaa tggtaatcgt attcaactac
    11521 gctttgcgac cttactagct aagaaaatca agtaaacaca catgaagatt aggaattttc
    11581 ctgatctttt ttctttttta cgaatgatat agaaaaggag ggaattcatg tttgttgcga
    11641 gagatgctag gggagaattg gtaaatgtgt tagaggataa acttgagaag caagcataca
    11701 cctgcccagc ttgtggaggc cagctccatt tgcgtcaagg accaagtgta cggacgcatt
    11761 ttgcccataa atccttaaaa gactgtgatt ttttctttga aaatgaaagt ccagaacacc
    11821 tggccaataa ggaatccctc tatcactggt tgaaaaaaga gacaaaggtt caattagagt
    11881 acccgctttc agaacttaaa cagattgcgg atgtatttgt aaatggcaat ctagctctag
    11941 aagttcagtg tagtcccttg cctcagaaag tccttaaaga gcgaagtgag ggatatcgta
    12001 gtcagggtta ccaagtactg tggttgctgg gtcaaaaact gtggctcaag gagcgtttga
    12061 ctcgtctaca gcaaggtttt ctttatttca gtcaaaacat gggcttttat gtttgggaat
    12121 tagacaagga aaaacaagtt ttaagactca aatacctgat ttaccaggat ctccgcggta
    12181 aactccatta tcaaatcaag gaattttcct atggtcaagg tagtttattg gaaatattgc
    12241 gtcttcccta taagagacaa aaaatatctc attttacagt ttctgaggac aaggacatct
    12301 gtcgctatat ccggcaacaa ctttattatc aaaatctctt ttggatgaaa gaacaagcag
    12361 aagcctatca aaagggagaa aatatcctga cttatggact gaaagaatgg tatccacaaa
    12421 ttcgaccaat agtgggcaaa tttttccaga ttgaacaaga cttgactagc tattatcagc
    12481 acttttatac ctattaccaa aaaaatcctc aaaatgattg gcaaaagctt tatccaccag
    12541 ccttttatca gcaatatttc ttgaaaaata tggtagaata gaaaggatgg aggaatctaa
    12601 tggtattaca aagaaatgaa ataaatgaaa aagatacatg ggatctatca acgatctacc
    12661 caactgacca ggcttgggaa gaagccttaa aagatttaac agaacaattg gagacagtag
    12721 cccagtatga aggccatctc ttggatagtg cggataacct actagaaatc actgaatttt
    12781 ctcttgaaat ggaacgccag atggagaagc tttacgttta tgctcatatg aagaatgacc
    12841 aggatacacg tgaagctaag tatcaagagt actatgccaa ggccatgaca ctctacagcc
    12901 agttagacca agccttttca ttctatgagc ctgaatttat ggagattagc gaaaagcagt
    12961 atgctgactt tttagaagct caaccaaagc tgcaggttta tcaacactat tttgacaagc
    13021 tcttgcaagg caaggatcac gttctttcac aacgtgaaga agaattattg gctggagctg
    13081 gagaaatctt tggttcagca agtgaaacct tcgctatctt ggacaatgcg gatattgtgt
    13141 tcccttatgt cctagacgat gatggtaaag aagttcagct atctcatggg acttacacac
    13201 gtttgatgga gtctaaaaaa cgtgaggttc gccgtggtgc ctatcaagct ctttatgcga
    13261 cttacgaaca attccaacac acctatgcca aaactttgca aaccaatgtt aaggtgcaaa
    13321 attaccgtgc taaagttcgt aactacaaga gtgctcgtca tgcagccctc gcagcgaatt
    13381 ttgttccaga aagtgtttat gacaatttgg tagcagcagt tcgcaagcat ttgccactct
    13441 tacatcgcta tcttgagctt cgttcaaaaa tcttggggat ttcagatctc aagatgtacg
    13501 atgtctacac accgctttca tctgttgaat acagttttac ctaccaagaa gccttgaaaa
    13561 aagcagaaga tgctttggta gtcttgggtg aggattactt gagccgtgtt aaacgtgcct
    13621 tcagcgagcg ttggattgat gtttacgaaa atcaaggcaa gcgttcaggt gcctactctg
    13681 gtggttctta cgataccaat gcctttatgc ttctcaactg gcaggacaat ctggacaatc
    13741 tctttactct tgttcatgaa acaggtcaca gtatgcattc aagctatact cgtgaaactc
    13801 agccttatgt ttacggagat tactctatct ttttggctga gattgcctca actaccaatg
    13861 aaaatatctt gacggagaaa ttattggaag aagtggaaga cgacgcaaca cgctttgcta
    13921 ttctcaataa cttcctagat ggtttccgtg gaacagtttt ccgccaaact caatttgctg
    13981 agtttgaaca cgccattcac caagcagatc aaaatgggga ggtcttgaca agcgatttcc
    14041 taaataaact ctacgcagac ttgaaccaag agtattatgg tttgagtaag gaagacaatc
    14101 ctgaaatcca atacgagtgg gctcgcattc cacacttcta ctataactac tatgtatatc
    14161 aatattcaac tggctttgcg gccgcctcag ccttggctga aaaaattgtc catggtagtc
    14221 aagaagaccg tgaccgctat atcgactacc tcaaggcagg taagtcggac tatccactta
    14281 atgtcatgag aaaagctggt gttgatatgg agaaggaaga ctacctcaac gatgcctttg
    14341 cagtctttga acgccgttta aatgagtttg aagcccttgt tgaaaaatta ggattggcat
    14401 aaaatggttg aatcgtatag taagaatgct aaccataaca tgcgtcgtcc tgtcgtcaaa
    14461 gaagaaattg tagacttgat gcgtcagcgt caaaagcagg tcacaggttt cttgaaagaa
    14521 ttggaagact ttgcccgcaa ggaaaatatt cctattattc cccatgaaac ggttgcttat
    14581 ttccgttttc ttatggaaac catgcagcct aaaaatattc tggaaattgg gacggctatc
    14641 ggtttttcag ctctcttgat ggctgaacat gcgccaaatg ctaagattac aactattgat
    14701 cgtaatccag aaatgattgg ttttgccaag gaaaattttg cccagtttga cagtcgcaag
    14761 caaatcactc tcctagaggg agatgcggtg gatgtcttat ctacactgac agagtcttat
    14821 gatttcgtct ttatggattc tgccaagtct aaatacatcg tctttctgcc agaaatcctc
    14881 aaacatttgg aagttggtgg tgtggttgtc ttggatgata tttttcaagg cggtgatgtt
    14941 gccaaggaca ttatggaagt ccgtcgaggt cagcgaacca tctatcgagg ccttcaaaga
    15001 ctatttgacg caaccttaga caattcagaa ctcaccgcaa cattagtgcc tttaggagat
    15061 ggtattctca tgcttcgtaa aaatgtagca gatgttcaat tgcctgacag cgaatgattt
    15121 tcagaaaaat ttaagaaaaa atagtaaaat agatagagta acacttatct caaaggagta
    15181 gacatgaaga aaaaattatt ggcaggtgcc atcacactat tatcagtagc aactttagca
    15241 gcttgttcga aagggtcaga aggagcagac cttatcagca tgaaagggga tgtcatcaca
    15301 gaacatcaat tttatgagca agtgaaaaac aacccttcag cccaacaagt cttgttaaat
    15361 atgaccatcc aaaaagtttt tgaaaaacaa tatggctcag agcttgatga taaagaggtt
    15421 gatgatacta ttgccgaaga aaaaaaacaa tatggcgaaa actaccaacg tgtcttgtca
    15481 caagcaggta tgactcttga aacacgtaaa gctcaaattc gtacaagtaa attagttgag
    15541 ttggcagtta agaaggtagc agaagctgaa ttgacagatg aagcctataa gaaagccttt
    15601 gatgagtaca ctccagatgt aacggctcaa atcatccgtc ttaataatga agataaggcc
    15661 aaagaagttc tcgaaaaagc caaggcagaa ggtgctgatt ttgctcaatt agccaaagat
    15721 aattcaactg atgaaaaaac aaaagaaaat ggtggagaaa ttacctttga ttctgcttca
    15781 acagaagtac ctgagcaagt caaaaaagcc gctttcgctt tagatgtgga tggtgtttct
    15841 gatgtgatta cagcaactgg cacacaagcc tacagtagcc aatattacat tgtaaaactc
    15901 actaagaaaa cagaaaaatc atctaatatt gatgactaca aagaaaaatt aaaaactgtt
    15961 atcttgactc aaaaacaaaa tgattcaaca tttgttcaaa gcattatcgg aaaagaattg
    16021 caagcagcca atatcaaggt taaggaccaa gccttccaaa atatctttac ccaatatatc
    16081 ggtggtggag attcaagctc aagcagtagt acatcaaacg aatagtccaa atcaatgagt
    16141 cagggaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata
    16201 gtacaaggtt tgtactgccc cccaaaaaag ttagacaatt aatttatccg aaggatttag
    16261 ttctgtattg cacagagcta agtcctttta gttttatctt aattctctta ttgttgtaat
    16321 aatcaatata gtctataatg gcttgttcca attgattaag tgatttaaat gtttgctcat
    16381 agccataaaa catttcggat tttaaaatgc caaagaaaga ttccatccta ccgttgtctt
    16441 ggctgtttcc tttgcgtgac atagatgctt gaattccctt actctctagg aagcgatgat
    16501 aagaatcgtg ttggtattgc cagccttggt cactatggag aatcgtattc tcgtagtgct
    16561 tctctttgaa tgcctgttcc aacattaacg atcaatcaat ttaatcatgt acctaatatt
    16621 agaattgttt atctcaaatt tatttgaaag tttctctaag ctatatcctt gttttctaag
    16681 ttcatagatc tgaactttat catcataagt taatttcata ataaaaacac cccaaaagtt
    16741 agattttttc tgtctaactt ttggggggca gttcatttaa cacctgataa tatgcgtttt
    16801 ttgattttaa agactttttg accagtctca tttttttaac ttgatactca gtgcaaagca
    16861 aagattaaac taggaagcta gctgtaggct gctcaaagaa cagctttgag gttgtagata
    16921 aaacttgtga ggtcaccaac atatataatg tgaagctgac gtggtttgaa tagattttag
    16981 aagagtatga gtctggaagt tttaatggat aatgcaagat tccatagaat gggtaagcta
    17041 gagttcttat gtgaagagtt tgggcataaa cttttacctt ttcctcccta ctcatcttag
    17101 tatagaaaag tgaatctgaa atagtacata actgcttcta aaacattctt ataaattgat
    17161 ttaaattctc aaatcatatt attcagttct tatttcattt tgttctacaa tcctgttgag
    17221 aagacacgtg ttcatatcaa aaaggtattg gcaagttgca ataccttttt acgaggctct
    17281 gttgtcttat ttttgtttca actgactata tctcctatgg ttctagttca gaaggctagg
    17341 ctataattat gattgataag aagtatcatt ccaagtattg ggagtgaatg tttcaaaatc
    17401 atgggtttct ataatggtca ggctggcatt tgctagaccg ccatctttac gaagaagtgg
    17461 ttctttatag cctaggagag tacgaagact ggcagtaaga ttggcgccgt gtccgacaat
    17521 tagaatacgt tcagctggac tatcttttaa tgatttgata aattggatgg tccgttgagt
    17581 tgtactatag agggattcgg ctccgaacat tcgagtgtca aattgagcaa gatttgaacg
    17641 aaaagcctgg atttgttgcg ggtaaatagc ttccaaggtt gcaattttca aaccttctaa
    17701 cttcccaagt tgccattcac ggagattagg aacgatttct aaagaacagg gggtatagag
    17761 ttgactttgg ataatctcag cagatttgac cgctcgaggt aaatcacttg aataaatctg
    17821 atcaaaagga atttccttga gatactgacc aagtcgtttt agggtttcaa tggattcagg
    17881 aagaagagga gaatcaccac tagcaccttg aaaacgacct tcttggttcc agagggtacg
    17941 accgtggcgg acaaagtaga gtttcattac ttgatgtcct ccaaaatatc tacaaagtct
    18001 gcctttacaa agctagccaa gtcttgtggc gcgacgataa tgctgtgtcc gacttcgcct
    18061 gcagagacaa tcatttgatc caaatctaga gcaattttat cgataaaaat gggataattg
    18121 tgtttctgac gaattccgac aggattattg gctccatgaa tgtaaccagt tgttttttct
    18181 aagtcctttt gtggaatcat gctcactttt ttattgccag aaattttagc tagtttcttt
    18241 tcagacaagt gctgagtgat agggacaatt ccgataatcg gtccggtctt gtctcccaaa
    18301 agcgccaagg ttttgaaaat ctgatctcgt tcataacctt gaggaagctc tccttctagg
    18361 gcattgattt gaatcccctg atgagggata gctgctttag ataggatttg ttccaccaat
    18421 gtttttttga ttttaacttt ttttgccatt atttatattt atcctccaat tgactcatcc
    18481 aaataccaag ccagattccc agcgcaaaga agaaggcgat gatgacataa ccgacaagtg
    18541 aaagtcctgt gtattggata ctttcagcgt ttcctgcatt tggaattaag atcaaaaggg
    18601 tacttgatag gacgataccg atgatgaaat gatagacgtg tgagtggtag ttgtttaagg
    18661 cataatccat caattttgaa aaaacgatga gagttgcacc tgcaccaatt ccaatcggaa
    18721 agaaggttcc caagagatca aaagttttaa aaccagtcaa cataggagca tagagtccca
    18781 aaatcaaaag taagttcgat gggctgaggc caggaaccaa gacgccaagg gccaatagtg
    18841 cgcctgctag gacgaagtta agaaagctgg cgcttaaggt tccaacgaca aaatttaagg
    18901 catagagtcc taatccagaa atgataaagg ttgtccataa ccaagctaaa tcaatcttgt
    18961 ctcggtcaga ttctcgagtt gattctttga ggaggctagg aactgtaccg ataatagctc
    19021 ccgcaaagct ccataataca aaaacctgat aattttcaag caggtattca atcgggtagg
    19081 aaaataagcc gattcccaga agcataccga tggcaactgg aataaagtac aaaacatttt
    19141 ctttaaagtc tttaaaggga tgggccagaa agccaatcat tcgttcatag attcctaaga
    19201 ttgctgctag aacccctccg gaaattcccg gtaggataaa tccaagagca attacaatcc
    19261 ctttaataac gcgtgctaac catgagagca tatatttcct ccaactattt ctatttcaaa
    19321 aaatccttac tatattgtat cacaatcaga cacaaaaaga aaaagcaaat gataaacaaa
    19381 tgcttttaag gttttaaaaa aagttttcga aaggtttctt ctttattttt taagggagag
    19441 ataacgttga tatctaaatc gtggtcaaag ccagcaattt ttcctttaga tgtgtattgg
    19501 tgaatatcat aatctaaatc agttttagga ctgctctcca aaaatcctga gtctgagccg
    19561 taggacggaa tccaaacaga ggtaaacttg cctgtatcaa tactgtgttc ttccatgaag
    19621 tagacaccaa cgtagatgcc gatgttttta gcacctagtg atgctagttt tgctcgaaag
    19681 ttttcgacac cttcgttcat attagacatg gttttgtctt ccacgtcaag ccaatagtaa
    19741 ctagggctgt aaggagaggc agcattgtag aaaacttcgg cagccttttc catttcttgg
    19801 acactttttc cagctacata agcgtagaca gcaactggga cattccgctt ttgaagttca
    19861 gtgatatgac tcttataggc cttgtctatt ccattgataa atgaagcatc attttctttt
    19921 gttgtttgag caccactgtg aacacgaaca atagcacctg aaatattttg tgagagggca
    19981 tcgtagttga tttcctcagg acgctgccag ccagagaggt caataatcgg tttgtctaag
    20041 tgtttcaaag cctgtgcttc aatctgtgct atattggatt ttgttttaaa cgattggctg
    20101 tcattaagtg ggcgattgat gattaaaatg aacatcataa tcccaaaaaa actaaataaa
    20161 ataagtggat gaatttgttt tctcatatct tataattcta ccctaaaaat caaaaaaaat
    20221 caaaaaaatg ggttaaggaa gagactttag agcatttttt cattcaagag tgcggaatga
    20281 tttgaaatat ggtataataa aagggaattt ctacagaaaa gagaagatta tgtcaaattt
    20341 tgccattatt ttagcagcgg gtaaagggac tcgcatgaaa tctgatttgc caaaagtttt
    20401 gcacaaggtt gcgggtattt ctatgttgga acatgttttc cgtagtgtgg gagctatcca
    20461 acctgaaaag acagtaacag ttgtaggaca caaggcagaa ttggttgagg aggtcttggc
    20521 tgaacagaca gaatttgtga ctcaatctga acagttggga actggtcatg cagttatgat
    20581 gacagagcct atcttagaag gtttgtcagg acacaccttg gtcattgcag gagatactcc
    20641 tttaatcact ggtgaaagct tgaaaaactt gattgatttc catatcaatc ataaaaatgt
    20701 ggccactatc ttgactgctg aaacggataa tccttttggc tatggacgaa ttgttcgtaa
    20761 tgacaatgct gaggttcttc gtattgttga gcagaaggat gctacagatt ttgaaaagca
    20821 aatcaaggaa atcaacactg gaacatacgt ctttgacaac gagcgtttgt ttgaggcttt
    20881 gaaaaatatc aataccaata acgctcaagg cgaatactat attacagacg tcattggtat
    20941 tttccgtgaa actggtgaaa aagttggcgc ttatactttg aaagattttg atgaaagtct
    21001 tggggtaaat gaccgtgtgg cgcttgcgac agctgagtca gttatgcgtc gtcgcatcaa
    21061 tcataaacac atggtcaacg gtgttagctt tgtcaatcca gaagcaactt atatcgatat
    21121 tgatgttgag attgctccgg aagttcaaat cgaagccaat gttatcttga aagggcaaac
    21181 gaaaattggt gctgagactg ttttgacaaa cggtacttat gtagtggaca gcactatcgg
    21241 agcaggagcg gtcattacca attctatgat tgaggaaagt agtgttgcag acggtgtgac
    21301 agtcggtcct tatgctcaca ttcgtccaaa ttcaagtctg ggtgcccaag ttcatattgg
    21361 taactttgtt gaggtgaaag gatcttcaat cggtgagaat accaaggctg gtcatttgac
    21421 ttatatcgga aactgtgaag tgggaagcaa cgttaatttc ggtgctggaa ctattacagt
    21481 caactatgac ggcaaaaaca aatacaagac agtcattgga aacaatgtct ttgttggttc
    21541 aaattcaacc attattgcac cagtagaact tggtgacaat tccctcgttg gtgctggttc
    21601 aactattact aaagacgtgc cagcagatgc tattgctatt ggtcgcggtc gtcagatcaa
    21661 taaagacgaa tatgcaacac gtcttcctca tcatcctaag aaccagtagg agcctatcat
    21721 ggagtttgaa gaaaaaacgc ttagcagaaa agaaatctat caaggaccaa tatttaaact
    21781 ggtccaagat caggttgaat taccagaagg caagggaact gcccaacggg atttgatttt
    21841 tcacaatggg gctgtctgtg ttttagcagt aacggatgaa caaaaactta tcttggtcaa
    21901 gcagtaccgc aaagctatcg aggcagtctc ttacgaaatt ccagccggaa aattggaggt
    21961 aggagaaaac acagcccctg tcgcagctgc ccttcgtgaa ttagaggaag aaacagccta
    22021 tacagggaaa ttagaactct tgtacgattt ttattcagct attggctttt gtaatgagaa
    22081 gttaaaacta tatttagcaa gcgatttgac aaaagtggaa aatccgcgtc cgcaggatga
    22141 ggatgaaacc ttggaagtcc ttgaagtgag cttagaagaa gcgaaagaat taatccaatc
    22201 aggtcatatc tgtgatgcca agacaattat ggctgttcag tattgggagt tgcagaaaaa
    22261 atagaggagg tcagtatggg taaatcttta ttaacggatg aaatgattga aagagctaat
    22321 agaggcgaaa aaatttcagg tcctcctttg ctagatgata atgaggaaac taagatttta
    22381 ccaacctctt cttcccgttt tggttatgcc aatcctaagg atcatggttt tagccaggaa
    22441 accttgaaga ttcaggtcga accatctatt cataaaagcc gtcgtattga aaataccaag
    22501 agaaatgtct tcaattctaa gttgaataaa atcttattcg cggtcatctt tctcttgatt
    22561 ttgcttgttt tagcaatgaa acttttgtaa tagaaaagga attgaaatga aaataggaat
    22621 tattgctgct atgccagaag aactggctta tctggtccag catttagaca atgcccagga
    22681 gcaagttgtt ttggggaata cctatcatac aggaaccatt gcttctcatg aagtcgttct
    22741 tgtagaaagt ggaattggta aggtcatgtc tgctatgagt gtggcgattt tggctgatca
    22801 tttccaggtg gatgccctta ttaatacggg ttcagctggg gcagtagcag aaggtatcgc
    22861 tgttggggat gtcgtgattg ctgacaaatt agcctatcat gacgtggatg tcacagcttt
    22921 tggctatgct tatggacaaa tggcgcaaca accgctttat ttcgaatcag acaaaacctt
    22981 tgttgctcaa atccaagaga gtttatctca attggaccaa aactggcatc ttggtttgat
    23041 tgctacagga gatagttttg ttgcaggaaa tgacaagata gaagcgatta agtcccattt
    23101 cccagaagtt ttagccgtgg agatggaggg ggcagctatt gctcaagcag cgcatgccct
    23161 caatctccca gtcttagtca tcagagctat gagtgacaat gccaaccatg aagcaaacat
    23221 cttttttgat gagtttatta tcgaagctgg acgtcgctct gcccaagtct tgttgacctt
    23281 tttgaaggct ttagattaag tggaaatttg acagtttttc tagcttatga taagatttaa
    23341 gtaaagaaaa gctagaaaac gtttcagagg atattatgag tattgaaatg accgtcagtg
    23401 agattgcaga ggtcttagga ttatctcgcc aagcaatcaa taaccgtgtc aaagaattac
    23461 cagaagaaga cacagataaa aatgacaaag gggtaacagt tgttaccaga agtggcttga
    23521 ttaagctaga agaaatctat aaaaaaacga tttttgaaga tgaacctgtc agtgaagatg
    23581 tcaaacaacg tgaactgatg gagattctag tggatgagaa gaatgcagaa attcttcgtc
    23641 tttatgaaca attaaaagcc aaggatcgtc agttatcaga aaaagacgag cagatgcgta
    23701 tcaaagaccg tcagattgct gagaaagaca aacaattaga tcagcaacaa caattgaccc
    23761 ttcaagccat gaaggatcaa gaaaatctta agctagagct ggaccaagca aaagaagaag
    23821 tccaatccac taaaaaaggc ttttttgctc gtttatttgg aggataatca aggagctgtt
    23881 taggttaaat gctaacctga tggcttcttt tgtttgtgaa tagtatagtt gattagaaca
    23941 gagacagtag aggagaggta cagaatggaa cgattagaag attacattgc ttttgattta
    24001 gaatttaatc agcatgaagg acaaacacac ttgattcaag tatcggcagt gcgttttaga
    24061 gatggtcggg aaatcgatgc ctatgattcc tatgttcata ccagcgtccc tctaaaaagc
    24121 tttatcaatg gtttgaccgg gattacagct gagaccttaa aagatgctcc tccagttgag
    24181 aaagtcttag aagaattcca agagtttgtg ggttctttgc tgatgatagg ctacaatgct
    24241 gctaaaagtg atttacctat tttagcagag catggtttag actatagcca acagtacaag
    24301 gtggatttgt atgatgaagc ttttgaacgt cggagttcag atttacatgg tattgccaat
    24361 ctcaaattgc aaactgttgc ctcatttctt ggatttcaag gtcagtctca taatagttta
    24421 gaggatgctc ggatgacggc gcgtgtttac gaatccttct tagagtcgga tcaagctagg
    24481 gaattgttag agacagaaag tagcttatca aacaatcctt ttggtggctt ggacttgtct
    24541 caattatttg actaggagtg cctatgaaac ctgaaaaacc taaaaaattg ggtcttaaac
    24601 agatttacct caatcttgat aaaatcctct ttctattttt cttgattttt atgatagtgg
    24661 agtatttgtg ggtaccattc aattcatggt tggctagctt cttattagat cagacaggtt
    24721 atctttttat ttcctataac aatgtcttag ccatccttac tcattctcca ttgattagtc
    24781 tagctttttt agccttgatt gtaattaact ttctggttgc ttattttcaa ataggactcc
    24841 tctttattgg tgctcgtcat ctcctctata atgaaaagcg aaggctaatt gagtatatcc
    24901 gcaaggtttt ccatgaaagt tttgaattta tgaaaaagct aactggcgct aaagccttgt
    24961 ttatcttttt ctatatagct atgctgtttc cttttatacg gaaaatgctg aagatttatt
    25021 atcttaataa aatcgtcatt ccagagttta tccaagctta tttagaagat aaatattgga
    25081 tgtggtggct gagcatccta cttctatctc ttatctttct ctatgtctct gtcagattga
    25141 tgtttgccct tccgaagatt gtatatgatc agctgactgt tcgagaagca gtgatgttta
    25201 gcttggagaa aaccaagaag agagttactt tttatgcttg gaatttattt tacatcttgc
    25261 tcaaagcaca tttattattt tatcttcctt tgattccttt attattggct caaactttgg
    25321 tagatgatat cactcagaga gagtctctga ttcttggtat tttgaatttt gttgtgatta
    25381 aaaatctcta ttatatggct ctgacttatt ttttggttaa atttgtttca tttttgacag
    25441 gaaaggagct ggatatgctt cctaggagag aaaaagatca catcgtgcga tggggtgtca
    25501 tgacttgtgc cagtcttttc tttgccttag aaggttatat ttatctggag gctcccatgg
    25561 ttcatctacc tcaacttatt tctcaccgag gggtttccaa tgcaaatggg attcaaaata
    25621 cagtagagtc cttggaaact acagcacaac tcaaaccaga cttggtggag acggacgtgc
    25681 aggaaacaaa agatgggcag tttgtcatga tgcatgatgc taacttgaaa aatctagcag
    25741 gtatcaataa aagtcctcaa gacttaaact tggaggagct taaagggatt gatatttttg
    25801 aaaatggcta ccagactaaa atttcaagct ttgaagatta tctcagtcga gccaacgaac
    25861 ttggtcaaaa attactaatt gaaattaaaa ccagtaaaaa agatagtcca gacatgatgg
    25921 accgcttttt agcccgttat gctgcaaagc tcaagattta tggacatcaa atccagtctt
    25981 tagactacca tgttgtcgaa aaagtaagac agtatgatgc cgaactgcca gtttatttca
    26041 tcatgcccta caattctgtc tttcctaaaa caagagcgac aggatatact atggagtact
    26101 caaccttgga tgaatatttt gtaagcaaac tatggacaac ggatcagaaa ctttatgtct
    26161 ggactgtcaa tgattcagaa gctatcagca aatctcttca cttaggagta gatggagtga
    26221 ttacagatga tttggaaaaa gttcagcggg aaatagaagt agcccaagaa gatccagaat
    26281 atacggattt gctcttgaaa aaagcattgg aattctttga attttagtaa taaaaaagag
    26341 gaacggttgt tcctcccatg ataggtaagt attcttgtga atgcttgctt ttttgtggtt
    26401 gcaatccgtt tacgagaatt gtttgtattg ttcttgtttc aatttacttt atagtgcttt
    26461 gaagttggaa tgctacacta taacttctaa aatatagtga aatgaaccaa aaatagtaca
    26521 caatgtggta taatctt
//
LOCUS       DAVMCG010000024        25246 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVMCG010000024 DAVMCG010000000
VERSION     DAVMCG010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25246
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.025"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(359..1219)
                     /locus_tag="VYP66_001272"
     CDS             complement(359..1219)
                     /locus_tag="VYP66_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1850823.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAIMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(1235..2512)
                     /locus_tag="VYP66_001273"
     CDS             complement(1235..2512)
                     /locus_tag="VYP66_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1850824.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(2505..3056)
                     /locus_tag="VYP66_001274"
     CDS             complement(2505..3056)
                     /locus_tag="VYP66_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850825.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENKASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(3072..4331)
                     /locus_tag="VYP66_001275"
     CDS             complement(3072..4331)
                     /locus_tag="VYP66_001275"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1850826.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            complement(5474..5632)
                     /locus_tag="VYP66_001276"
     CDS             complement(5474..5632)
                     /locus_tag="VYP66_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850827.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(5642..6952)
                     /gene="obgE"
                     /locus_tag="VYP66_001277"
     CDS             complement(5642..6952)
                     /gene="obgE"
                     /locus_tag="VYP66_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1850828.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(7016..7150)
                     /locus_tag="VYP66_001278"
     CDS             complement(7016..7150)
                     /locus_tag="VYP66_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1850829.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(7209..7385)
                     /locus_tag="VYP66_001279"
     CDS             complement(7209..7385)
                     /locus_tag="VYP66_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1850830.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(7416..8741)
                     /locus_tag="VYP66_001280"
     CDS             complement(7416..8741)
                     /locus_tag="VYP66_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1850831.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRSSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(8757..9800)
                     /gene="cpoA"
                     /locus_tag="VYP66_001281"
     CDS             complement(8757..9800)
                     /gene="cpoA"
                     /locus_tag="VYP66_001281"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1850832.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(9915..10244)
                     /locus_tag="VYP66_001282"
     CDS             complement(9915..10244)
                     /locus_tag="VYP66_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1850833.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(10258..11367)
                     /gene="rpoD"
                     /locus_tag="VYP66_001283"
     CDS             complement(10258..11367)
                     /gene="rpoD"
                     /locus_tag="VYP66_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1850834.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(11370..13130)
                     /gene="dnaG"
                     /locus_tag="VYP66_001284"
     CDS             complement(11370..13130)
                     /gene="dnaG"
                     /locus_tag="VYP66_001284"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1850835.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(13220..13978)
                     /locus_tag="VYP66_001285"
     CDS             complement(13220..13978)
                     /locus_tag="VYP66_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850836.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(13975..14841)
                     /locus_tag="VYP66_001286"
     CDS             complement(13975..14841)
                     /locus_tag="VYP66_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850837.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMDLMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(14910..15914)
                     /locus_tag="VYP66_001287"
     CDS             complement(14910..15914)
                     /locus_tag="VYP66_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1850838.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(16027..16244)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16327..19023)
                     /gene="ppc"
                     /locus_tag="VYP66_001288"
     CDS             complement(16327..19023)
                     /gene="ppc"
                     /locus_tag="VYP66_001288"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1850839.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWHNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFDSSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(19043..20272)
                     /locus_tag="VYP66_001289"
     CDS             complement(19043..20272)
                     /locus_tag="VYP66_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1850840.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(20428..20730)
                     /locus_tag="VYP66_001290"
                     /pseudo
     CDS             complement(20428..20730)
                     /locus_tag="VYP66_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(21178..21399)
                     /locus_tag="VYP66_001291"
     CDS             complement(21178..21399)
                     /locus_tag="VYP66_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1850841.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            complement(22079..23290)
                     /locus_tag="VYP66_001292"
                     /pseudo
     CDS             complement(22079..23290)
                     /locus_tag="VYP66_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(23292..24536)
                     /locus_tag="VYP66_001293"
     CDS             complement(23292..24536)
                     /locus_tag="VYP66_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HEV1850842.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQGLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMLVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            complement(24560..>25246)
                     /gene="galE"
                     /locus_tag="VYP66_001294"
     CDS             complement(24560..>25246)
                     /gene="galE"
                     /locus_tag="VYP66_001294"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1850843.1"
                     /translation="KKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYI
                     EVLLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPY
                     LNIFGVDYSTPDGTCIRDYVHVNDLAYGHRKALEYIFNTDEGLYEVINLGSGVGFSVF
                     EILHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKW
                     QQKHPNGYDD"
BASE COUNT         7736 a         5489 c         4167 g         7854 t
ORIGIN      
        1 tttcgcagga agtctaatct aaaaaaggta aatttaagat tggcaatacg aacgttaaac
       61 agaattccat ttctcttttt agaatcaaaa cgacaatatt gtggaatctc tacaggaaca
      121 atagactgcg acactaaaat atcctctctt agttttactt tactaatagt atataggagg
      181 agagccctga atcctagacc ctttgttatg atgcgcttac aaacagagtt ggaaaaaatc
      241 ttaaaagcag aaaaacgcat gatatcagcc cctaacactt gatacaatgc gttttattat
      301 gaaaagatct actggatttt ttatcaaaat aaacttccag tagtcttttc actttttatt
      361 aataagttcc ttcttcacct tggctagtca agataacagg tccatctttc gtaatgacaa
      421 attggtgttc atactgacat gacaatccac cgtcaatggt cttatgcgcc caaccagttt
      481 tcatatctgt atcaatttcc caatcgcctg tattgatcat tggttcaatg gttaagacca
      541 ttccttcacg aagacggagt ccacgacctg caataccata gttaggaacc attggttctt
      601 cgtgcatagt tgggccaaca ccatgaccaa ccaaatcacg cactacaccg taaccacgac
      661 tttcagcgta ttcttgaata gccgcaccga tatcaccgat acgatttcca acaacagctt
      721 gctcaatacc cttgtacata gcttctttgg ttacatccat caagtttttg acttcttcgg
      781 acggtgtacc aacagcataa gcccaacatg agtctgctaa accaccagaa tagctctgag
      841 tgtatttttt catttgttca acattgttga agtttaattt tgagacattt aggtcagatt
      901 tagcaatggg acctcccaaa accatatcaa ctttgagcaa atcaccatct ttcaagatat
      961 aatgacgagg gaaagcgtga gccacttcat cgttaagaga gcaacaggta gcataaggat
     1021 agtccattat ggcaccgtca accccaatct gaagtggaag gaaattttct tctttacaac
     1081 gacggcggac atattcttca acttcccaca tatctacgcc tggcttaatc aaatcacgta
     1141 agcctatatg aatacttgct agaaaatcac cagccttgtc catagcttcg atttcacgag
     1201 ctgattttaa tgttatcatc ttttctccta gtttctaatt aattttaaca gtcacatttg
     1261 cttttgaaac aatctggtga ccatgataaa tatcgtaatc aattatagct gaccgtctcg
     1321 tatgatgaat aatccgtgcc tgaatgcgca atatatcatc tatctgaaca gcctgcaaaa
     1381 agtagatcag catctgctcg ataatgagat tgcgaccact attaacaact aaatcttggg
     1441 tcatgtgggt cagaatttct gccaatacac cattagccaa aactccattt ttttctagca
     1501 taaagggttc cactgtaatg actacttcat catggtgata agagagcttt tgtccaatct
     1561 gctcagaaaa agttggtaga gccgaaactt gggaacggct catcttctcc atgacatctc
     1621 gtcgcgtcac aacgccaagc aaagtttgat tgcttcgaac aactggtacc atttcaaagt
     1681 cttctgcgat catccgttga ctcacattgg caatatttgt cgataatcca accaaaaata
     1741 gactacgaga cataacctta tcaattgtcg tgcttggtga tttatcacca gcgtctctca
     1801 tggttacaac accaacaacg acctgatgtt gattgataac agggaaacgg ctgctacgat
     1861 tcttacgaac caagtccaaa taatctttaa ctgtatctgt ctctcttaga aaaccatact
     1921 catgactagg gcgataaagt ttctcaactg tcagaatatc agtcttgatt tggacatttg
     1981 acaaggcttt attgatcatg gtcgcgacgg taaaggtatc atgcttactt cttagaacag
     2041 gaatcccttt ttgattggcc agtttaagca catcatcatg aacctgaaat ccccctgtaa
     2101 ccagaactgc attttcattt tccaaggcta gcaactgaat acgggttcgg tctccgacaa
     2161 tcaagagccc cccatcatga aggtaagaca agatattttg ttcagtcatg gcaccaattg
     2221 aaaacttact aaactctctc tctaaacctt cttgcccagc cagaacctca gaagaagtca
     2281 cttctgcaat ttcagcaaac gttaatctct ctatagcaac tttctgggat ttaacacgaa
     2341 ttgttccact tctaggacgg gtctccacaa ttccacggtt ttcagcttct ttaatagccc
     2401 gataggctgt tccatcacta actcctagat gattcgaaat gctacgaaca ctgacccttt
     2461 tacctactgg taattcctcc aaatagctta gaatttcctg atgcttactc attgaactct
     2521 ccttttacat accgaaattc aagataatcc cgcatttttc ttgtgtaacg atcacttccc
     2581 ttaaactgac ggaacaaact aaatccagac ttaagagcaa ctctttggct agctttattt
     2641 tcaaggtggg taatgataaa taattgtttt aagccaaatt cctcaaaaga aagctgacaa
     2701 atttttctaa caacctctgt cataaatcct tgcgaccaag catcttttct caaaaaatag
     2761 ccaagctcag cttctttttt gatttcatct aacttctcaa atttaataga accaatcatt
     2821 tgttgatttt tctggtcaca aattgcccac actcccaaag gggacttcat aaagtaattg
     2881 gccagtgcat attgactttc ttccagactt gcctgcgttg ggaaaataaa ttgaagattt
     2941 tctggatttg aagctatctc gcggaagtcc tgactatcac taaaaaagaa aggacgcaaa
     3001 tacaagcgat ccgtttcaaa aaaagaaaac attgctaatt tggtccaaat attcataaac
     3061 acctctacgg tttaatcctc aacaagtcta atatccgctc ctaaattacg taatttttcg
     3121 ataatatcag aataaccacg taagataaac tcgatattgg taatttcagt tttaccttca
     3181 gccataagcc cagcaatgac tagtgcagcc ccagctctta agtcggtcgc tttaacactg
     3241 gccccacgta aatcacgtcc acccgtgtac aaaatatgac catttgttgt cgaaatatcc
     3301 gcatccatct ttgctagttc aaaaacatga tttacacgtt tttcgtaaat cgtatcgaca
     3361 attgtaccac gaccattcgc tcttagtaaa agaggggtaa gcggttgttg caaatcagtt
     3421 gcaaagcctg ggtaaggagc tgtcttaata ttgattgctt tcaaattaga ctgttcctcg
     3481 acaaaaatgc tgtcttcaga tacagtcatt ctcactccca tttcttccaa cttagcaata
     3541 aacccttcca ggtgttcgta aagaacatta tttatacgaa ttcctttacc aactgcagca
     3601 gctaaagata tatatgttcc agcttcaatg cggtctggaa tcacctgatg acgtgtccca
     3661 tgtaatcttt caacaccatc aataatgatg atattagttc ctgccccacg gatatgggca
     3721 cccatattat tcaagagagt agctacatca ataatctcag gttcacgggc tgcattttca
     3781 ataatagtac gaccatttgc tttaaccgca gcaatcatcg tattaatcgt tgctcccaca
     3841 ctaaccgtat ccatgtaaat acttgcacca tgaagtcctg tatctttagc agataacttc
     3901 atgttatctc cctcgtagct agcagtggca cccatagctt caaacgcctt aaggtgtaag
     3961 tcaatcggac gaggaccaag atcacatcct cccggtagac caactgtcgc ttcaccaaaa
     4021 cggcctaaga ggctcccata aaaatagtaa gatgcacgaa gactgttaat tttaccataa
     4081 ggcattggaa tattttgaac acctcttggg tcaatctcca atacatcgtc ataacgctta
     4141 acagtagctc ccatcaattc catgatttcg acaagactgg ctacatccga aatatctgga
     4201 acgcaatcca aagtcaccac atcatcagcc aagataatag ctggaattaa ggcaacgaca
     4261 ctatttttag caccactaat agtgatttca ccttgcagtg gtaatccacc attgataaca
     4321 atttttctca ttctaagttt tcaatactct ttcaagattt ctaataaggt cttcaaaata
     4381 aagtatatca taaatttatc cttttttcca tccttttcaa ttttattgga taaatcagag
     4441 ttgacgagtt agtaactgaa ttactaatac tcaatgaaaa tcaaagatca aactaggaaa
     4501 ctagccgcag gttgctcaaa acactgtttt gaggttgtag atggaactga cgtagtcagt
     4561 atcctacaca tacgacaagg cgatattgac gtgatttgaa gagattttcg aagagtataa
     4621 tctttctcga atcgctattg cccctttttt atcccctaaa actgagtagg agctaagact
     4681 agatctctta tctaagtatc ggaatacggc tgttcaacta aattttagca agaacttctc
     4741 ccccttctct cagttcacag aagcgtttta tacataccgt cctatcagac agataaccgt
     4801 gactcaggat cacttctatc tgtcgttttc tctttatagt gatagacctc acgggataag
     4861 tcgtacatct ttcctcgtgt atacaagata taaggacgtt aaaaggttac agtgaaaata
     4921 gaaaatctta gtacgaattc aattactctc gtgatttacg catataggtt acgactacct
     4981 ttttggactt tagagtttga gaccccctta tccgctatat acgccttatt atcacgttcc
     5041 tgttcgtaga gccacgattt cgctatccct tcttctgaca attcttattt ccagcgtcag
     5101 acttaaaacg gtctatcccc agaccatttt aatctgctac ctcacgatag tcaggcttgg
     5161 gaatcgctat ttgactcgcc gagaactttg acatcagata tactataaca aattgaaata
     5221 agaatcaaac aatttaattt tgaaattcaa atcaatttat aacaatatag ttgattgaaa
     5281 ctagaatagt acatctctgc ttctaaaaca ttgttagaaa tcgattttac tgtcctgatc
     5341 gatttgtcct gttctcattt cattttacta tattttagaa gatatgctgt gctattccag
     5401 attcagtttg ctatacatgc ctgtcgtacc acaaaatccc gtgtctgatg aggcacggga
     5461 ttttttagct tctttactga gatggatttt cctttttagt tcgtgccaat ctcaaggcac
     5521 gatttggatt gagacgatta aatagttctt ccaatttctt ttcattccaa acgtctgcgg
     5581 cggaaacaaa attaccatcc gcatctcgga aagatatcgg tttatctccc ataccagtct
     5641 cctagtctac aaattcaaac tcaaatttac caatgcggac caaatcccca tctttagctc
     5701 cacgcgcacg aagggcttca tcaaccccca taccacgaag ctgacgggca aatttcatga
     5761 cagattcatc acgatcaaag ttggtcatat taaagagttt catgagtttt tcaccagaaa
     5821 gtacccatgt cgcatcgtca tcacgactaa tttcaaaggc tttttcttct tcgtcaaatc
     5881 catagtaagc ttcttcttcc atatcggact cgtcgtagag caaaaattct ggtgtcttgt
     5941 ctaacaattc agctgtagca tctaaaagtg ttgccagacc ttgcttggtc aatccagaaa
     6001 ttgggaagat agctggtaac tcttcaaatt catcataatt ttcagccaat tttttcttaa
     6061 agtcttcaag attttcctga ctctcaggca tgtccatctt attagctaca ataatctgtg
     6121 gacgctccat gaggcgaaga ttgtaagact ccagctcttt attgatagct aggtagtcct
     6181 catatggatc acggccttcg ctagctgaca tatcaatgat gtgaaggata acacgtgtac
     6241 gctcgatgtg acggaggaac tgagttccca aaccaacacc ttgactagcc ccttcaatca
     6301 aacctggcaa gtcggctact gcaaaggatt cacctgattg ggtgcgaacc atacctaaat
     6361 ttggtacaat agtggtaaag tggtaggcac caattttagg cttagctgag gtaataacac
     6421 ttaaaagtgt tgacttccct acagatggga atcctactaa accgacatct gccaagattt
     6481 ttagttccaa ttgtaactca cgttcctgac ctggttctcc attttcagag atttccggtg
     6541 caggattttt tggtgtcgcg aaacgaatat ttccacgtcc accacgacca ccgtgggcaa
     6601 cgataaattc ttgcccatgt tcaatcaaat ctgttaaaac cttgccagtc tccgcatcac
     6661 gaacagtcgt accttgtggt actcgaactc taaggtcctc agcaccacga ccatgcatcc
     6721 ctttggtcat ccctttttca ccagaatcag ccttgaaatg acgattgtag cggaaatcca
     6781 tcaaggtacg tagtccttcg tctacaacga agaccacatt gcctccacga ccaccatcac
     6841 caccccaagg gcctccatta gggacatatt tttcacgacg aaaggcaacc ataccatcgc
     6901 caccattacc agccttgacc ttaatcttag ctgtatctaa aaacatactc attatttctt
     6961 ctcactttaa aaaagggctg ggaaatccca gtcactaaat tttcttgaat ctattttata
     7021 gattactgag ggcaccaatt gcagttgcaa aaattcccaa taaacttgct actagcatga
     7081 taatcacgat aaacaaggtt attttctcaa acatagtttt tttacgattt ccattatctc
     7141 caaatgccat ttttctctcc ttcgttacat tctattttct attatcttag catgaattga
     7201 gctagttttc aatagtcagt tgctactggt gcgataatcc ataaaataat gtaagctaca
     7261 attccagctc cgtaacagca agtaagaaca ccccaaatga cttgaacgat agtcggatcc
     7321 atatccagat aatgggccac cccagcacaa acacccgcaa tctttttatc acgaccgctt
     7381 ctcattaatt gtttttttca tagctgttcc tctttctatt cttcatggtc tttccaatag
     7441 tctctcatac tgatcaactg tgtttttgaa gccttcaaca tgcgtctaga tccttttaca
     7501 ggtacagcaa ccacctgttg ctgaagatac aaaactgtct taaagatacg ctgactgacc
     7561 gtatcatctt tagccaaatc tttctggaag ttatttgaaa taatggcatc cagataaaac
     7621 tcatgcactc gtttcccaaa gttctcagct gaaatctcat acaatttctc tgataaggta
     7681 tgctcgttca tgtctggtgt tgcaatcagg gcttccaaaa tagcaccagc caaatcatgt
     7741 tctccatagt acaaggttcc aaacatttta tcactgatga ggttgttcaa ataaggattt
     7801 ccgtgagcaa tgacaggtgt tccactggct aagctttcca agtaggtcaa accttgcgtt
     7861 tcgcttgtcg atgccgaaat gaagaaatcc gccgctttat agtaaagagc cgtctcacta
     7921 ggagcaatca tccctgtaaa gatgactgag tcttgaatct ctaggttctg ggcttgctct
     7981 ttgaggtcat tcagataagg gccatcccca gctactacca gtttaacctt gtcttcctct
     8041 ttcagaacat cagcaaaggc tgctaaaact gcttgaatat ttttttcata ggagattctc
     8101 gaaagactaa gcaacgtctt ttcaccatct tgaatcccta gtttactacg cagttctttc
     8161 aaattttcct gcttgatttc cggacgctca aacttggcta attcaatccc agtaggaatg
     8221 acccgttttt caaccttgac cttataatca gatagcaagt cacggacaat ctcactaggg
     8281 caaataaccc catccacatc atgcaggaaa cctctaacca gatacttgac catactcgac
     8341 cggatcaaca tccccttagc aatataatgg acatagtctt catactgggt gtgataggta
     8401 tggatgactg gaattttcaa ttcacgcgca atccaaatcc ccaacaggcc aagagaaaat
     8461 tctgtctgag tatggataat atctagctga tactgtttag caatttcaag tgccttgcta
     8521 aaacctcggt aggcaaagcg acgatcctta aaagcaaaga aaggaacact tggaatgcgg
     8581 ataatttgcc aatcttcgta gcgattgaca tccttatctg tcgtcgtaaa gataaaaaca
     8641 gcatgtccct gcttttcaag ttctgttttc aaggttcgaa tactggtcgc aacaccagaa
     8701 acctgaggaa aataggtatc tgtaaataaa ccaattcgca tagattacct cactttttac
     8761 tttctcccta aagcggcttg tttctcataa aagtccaacc agatttgtaa cagatgctct
     8821 tcagaatact ctctggaaat attcttggcc ttttctttga gatcttttaa gacagcagga
     8881 tttgcttgat attccaaaat agcctctttc atctcttctc tacccgctgt cgcccgataa
     8941 tttccctcca aaatcacctt atagagatct aaatcacgca acataatagg agcctcacaa
     9001 ctcgcagctt ctaaaatagt cataggaaag agctcattgt aactaggcaa caagaaaaga
     9061 tccgctagag catacaattc gcgcatccgc tctggcgata caatgcctgg aaaaatcaaa
     9121 tttttagggg gattttccat aattttctta tagtgttcat aaccatctgt cataccacca
     9181 aaagagaagc caccagccca gataaaggta atctgaggca attcctcagc cagacggata
     9241 aagtcatcaa tccctttacg tttctgaact tgcccagcac ctactacgat aaactgattg
     9301 tcactaagac caagatctgt gcgcagtctg actacctctt cttgtggtag aggatgccat
     9361 ttttccttgt tgacaaagtt aggaatatag gtcacttttt cacgtggaat accagctgct
     9421 accaaatcct caataaacat aggattgacc acaaccaagt gctccatccg gttgtaaaaa
     9481 gaaaatacat agcgtttcac aattcccttt aagaaaaatg gaattttcaa acttccttca
     9541 agtgtagctg gcaagaaatg cacatagcca atctttctcc ctgagcgttt cttttggaag
     9601 gttgataaat aatagggaaa atcaatcgta tgaaagtgag tcacatctgc ctcgattgga
     9661 agattttctg taacaatcaa ttggtccttg gcagcacggt gaagaagacg aactaattca
     9721 cggtaagcac ctgaaactcc ctgtcctgct actttctcac ttgaactcaa catattgatg
     9781 cgtaatttct ttttctccat aactactatt atatcatttt ctttgaataa aatcagcaaa
     9841 agaaaggaga gactagagga aaagagggga aatttcctcg cttttccaac agtctctcac
     9901 atgcttttat atgtttactt aatgcctagg gcaatgcggg catagcgact cattttttca
     9961 actgtccagg ctggatacca gactaattta acctcagtat ccgttacttc tggaacctct
    10021 atcatagcat cataaatctg gtctgtcaaa aggtctgcta agggacaacc catagttgtc
    10081 aaagtcatgt caatctctgt ttgccctgtg tcaccgtcaa aacgaatctc atagatcaaa
    10141 ccaagattga caatatcgat tcccaactca gggtcgatga cttcttccaa ggctgttaaa
    10201 atccgtgttt tgatgttttc aatttgctct tctgtataag ccatattttc ctcactctta
    10261 gtcttcaata aaatcacgaa gcggtttgct gcggcttggt tggcgtagtt ttctcaaagc
    10321 ctttgcttca atctgacgga tacgctcacg agttacgtta aagactttcc ccacatcttc
    10381 aagtgtgcgc atttttccat catctagtcc aaaacgtaga cgcagaacat tttcttcacg
    10441 gtctgtaaga gtatctaaga tttcatccaa ttgctcacgc aagacgatac gagtcgtata
    10501 atccactgga ttttcaatta cttcatcttc gataaagtct ccaaggtggc tatcgtcctc
    10561 ttcaccgata ggagtttcaa gagatactgg ttcttgggca atcttcaaga tttcacgaac
    10621 cttatcaggt gtcatatcca ttcgttcagc aatctgttct ggtgtcggat cttgccccaa
    10681 ttcttgaagg agattccgct gttcacgaac caatttattg atagtttcaa ccatgtgaac
    10741 tgggatacgg atggtacgag cttgatccgc aatagcacga gtgatagcct gacgaatcca
    10801 ccaagttgca taagttgaaa acttgaaccc tttagaatag tcaaacttgt caaccgcctt
    10861 catcaagccc atatttcctt cttgaatcaa gtcaaggaac tgcatgccac gaccgacata
    10921 gcgtttggca atagaaacaa ccaaacgaag attggcttcc gcaagacgtt gtttggcttc
    10981 gatatcgcca gcttcaacag ccagtgccaa ctctttctcc tcttcattgg tcaagagagg
    11041 aacgacccct atttctttca agtacatacg gacagggtca ttgaccttag cagaagttga
    11101 cccaatcaag tcctcatcgc tgagttctgg ttcttcttca ttgctaagaa cacgcgcact
    11161 tggatttcct tcgttatctg tgatagaaat gcctgcatcc tgaatccgtt gcaagagatc
    11221 ttcaatccca tcagcgtcca aggtaaaagg aataaccaga cttgcattga tttcatcatc
    11281 tgttgctgtc cctttttgct tatgattacg gataaattct gctacctgta cgtcaaatgt
    11341 tgttacttct ttttgttttg ttgccattat tactccattc ttctcttttg ggaaattaaa
    11401 cgttccaatt cttctagggc tgtatctgta tctcctacat ggctagcttc ctgcaccttc
    11461 tttttgattc tcatattgtc ctgattcaag agagccttgt ttcgagtcat ctctacttca
    11521 ctaagttcct gcggcgatat ctcagcaggc aaatcctgag ctaaaacttg gtaccaagct
    11581 ctttcaactt cctctgtctg ctctgctaaa acttctggag gaagatttcc atactggcca
    11641 agcaagtcat ataagacctg aaattcaggt gtagcaaatg caaagtcttc tcgcaaacgg
    11701 taatcgttca aaacaagagg ggattccatc atccgataga gtagatgggc ttctgccctc
    11761 ataatagccg ataactgctt ggtgataggc atggtgattg gcgtcggtct ggaaattcct
    11821 tccatgcgat tctgcctttg cacctgacga ctctcattaa caatctgctc aatctgggta
    11881 taatcaaagg acgccagact gtcagctaaa atatgaatat agctgttttg agcagcgatg
    11941 gacttttctt gaacaatcaa gggagctatt ttttcaataa actcaatctg agcctgcaga
    12001 ttttcactgt tttcaggttt gtactgatga atgtagaact caatcggact aatacgagtt
    12061 tttgttaata gataggccaa gtcttctgga ccattttttt gtagatactc atcaggatcc
    12121 aagttatcag gcatgctaac gatttgcaca ggcatatcac caatttcatc caatgctttc
    12181 aatatcgcgg cttgcccagc cttatctcca tcgtaaacaa gaaccaattt cttggttaac
    12241 cttttcagat gctcaacatg ctctcgactc aaggccgttc ccatcgacgc cacagcattt
    12301 tcgattccag cccgataggc tgcaataaca tccatgaatc cttccatcag gtaaatctca
    12361 ctagcttttc cagaagatct ttttgcccta tccatatgat ataattcgta acttttgtta
    12421 aaaattgcag tcgatcggct gtttttatac ttagaagttt gtgaatccgt tttttgccag
    12481 atacgacctg agaaggcaat gacctttcct tggtcatttg tcaggggaaa cataatgcga
    12541 ttgtgaaagg tgtctacaaa ttgattggca tccgagagat aaaacaggcc tgaatccagt
    12601 aaatcctctt cacgatactg atcagacaaa cgttgataga gatagtttcg ttctggaggt
    12661 gctaaaccaa tccaaaaatg tttaagcact tcatctgtca aaccccgctg ataaaggtaa
    12721 tttctggcct cttctcccat agtcgttgtc atgagaatag catggtaaaa tttggctgca
    12781 tcttcgtgca tatcataaag agcttggtga ggcgaggctg gcttctgttc actataaagc
    12841 ggtttttcaa cctcaatccc gacacgctga cctaagattt ggacagcctc cataaaggta
    12901 accccttggt actcctcgat gaatttaaag acatcacctg agcgaccaca accaaaacag
    12961 tggtaaaact gcttatcctc tacaacgttg aaagaaggtg ttttttcacc atgaaaagga
    13021 cagagcccta gatagttccg tcctgccttt tgtaaagaaa tcacatctcc tatgacttcc
    13081 acaatgttgg cattgttttt gatttcttca atgacttgtt tgtcaaccat acacaatacc
    13141 tccatgttat catagtttac tttatatagt atactttatt tcagaaaaaa agtaaaccat
    13201 ttcactcatt ttccctactt tattcaaaga gttgataata atcagagatt ttcatttttg
    13261 ctttttcttc ttggtttaaa tcttggataa tccgtccttc tttcatgaca atcaagcgat
    13321 tgccgtattt gagagcatct tccatatgat gagtaatcat aagggctgtt agctgatctt
    13381 tcttaacaaa ttcatctgtc aattccatca aagcaacact agtctttgga tccagggcag
    13441 cagtatgctc atctaacagg agtaattcag gtcgcttcaa ggttgccatc aagagactca
    13501 aagcctgtct ttgtccacct gataagaact caatcggtgt attcaagtgt ttctcaagac
    13561 catttcctac tttttcaatg gttgcctgaa attcatcctt atagctagtc aagcgtcttg
    13621 gtaacaatcc acgcttttca ccacgaaact tggcgattaa aagattttca gcgaccgtca
    13681 tacggggagc tgtccccatc tttggatctt ggaagacacg agacaggtac ttggcacgct
    13741 tctcgggtga aaacttagtg agatcttcac ctaaaatacg gatagttcca ctagttagtg
    13801 ataaggtccc tgctatagtg ttaaagagag ttgattttcc agcaccattt ccgcccaaaa
    13861 tcgtgataaa gtcccgttca aaaatttcta aggaaacatc atttaaaata atcttttctt
    13921 catcaaagcc atttttaacg attttggttg cattttttaa ttctacaatt gctgtcattt
    13981 gcttaacttg gctcctttca agattgtttg cttaaatgtt ggaatcatga ggcagactgc
    14041 taaaatcaaa gcactgtata aacgaaggta acttgtatta aagccaagtg cgataactgc
    14101 ccacactaaa aattgataag cgatagaacc tacaacgata gtaaccaaac gctctgccaa
    14161 gctcaaactc ttgaaaataa cttctccaat aatcaaactt gcaagcccca caacgataac
    14221 cccgatccct cgagacacat cggcatagcc ttcttgctga gcaatgaggg cacctgcaag
    14281 ggcaatcaca ccatttgata agaccaagcc catgagatcc atgcgtccag tatgaatccc
    14341 gaaacttcta gccatatcag gattatcccc tgtagcaata taggcttgtc cgagtttagt
    14401 gtccaagaaa aagagcatga gagcaataac aatgctcaca aagatgagac ctgtcaagag
    14461 ttgattcaaa tccgaatcaa aaggcaaaac atcctgaatt tgcttggttc caagcaggcc
    14521 taaatttgca cgtcccataa tcaagagcat gattgagtga caagaagtca tcaccaaaat
    14581 ccctgagagc aaggttggga tcttcccttt tgtataaaga aggcctgctg ccattccagc
    14641 caaacaacct gctcctacag caacaagtgt cgctaaaaat ggattcacgc ctttggttat
    14701 caaagtgaca gcaacagctc ccccaagagg gaaggaacct tctgtcgtca tatctggaaa
    14761 gtttaaaatc ctaaatgtca taaagattcc cagacctaga atagcccaga caaatccttg
    14821 agaaataatg gaaacaatca tattttattt aatcctttct atattcatct ttttaaaaaa
    14881 tgggaagagt ctcctcctcc ctaccttatt tattcgatga cttgtcctgc ttctttgaga
    14941 acagactcag gaatagtaat acctagttct tgtgctattt ttttattgat gactgactta
    15001 ccagttgaaa agacattgac tggggtatcg gctggttttg cacctttcaa gacttgcaca
    15061 atcattttac ctgttgccac accaaggtca tgttggtcaa ttacaactga tgccaaacca
    15121 cctacttcta ccatagctgt cgcactggga taaattggtt tcttagaact ttgattgcta
    15181 gagacaaccg ttggaaatcc tgatgcaatg gtgttatcaa ttggaaccca aatagcatct
    15241 accttgctag tcataacagt gacagttgag gcaatttcat ttgttgaagg aactgcaaat
    15301 gtttccactg tcagacctgc tttttcagca taagccttaa attcttcgac ctgtgttttt
    15361 gaattgtctt cgctacttga gtaaagagct ccgattgttt tcacattcgg tgtcagagcc
    15421 ttgatgagtt caacttgttg ttgagctgga ttgtggtcag atacccctgt aacgttgcca
    15481 cctggttttt tcaaatcttt aaccaagtta gcaccaattg ggtctgtaat agcggccatg
    15541 ataaccggta ggtcttttgt tgcactagcc aacccttggg ctgctggtgt tgcgatacca
    15601 accacaaggt cattcccatt tgcaaccaat tgtttactca ttgtcgcaac cttactttgg
    15661 tcaccttctg agttcataaa atcaatttta acttgatcat ctttatatcc ttcttctgca
    15721 agtccatctt ggatcccttt ataaatcaaa tcaagggatg gatggctcac aaattgaagc
    15781 acaccaatct tggttatttt cttctcatcc ttattattct gaacttctga tttattcatt
    15841 gaagaataaa tcaagcttcc tgctactaag actgctaatg cagcaataat tccaattaaa
    15901 cgtttatttt tcattctgtt tctccttttt atttccttta acatatttca cttatctaaa
    15961 caagcgacgc cattgttttc tttccatact aacctccatc aaaaaaatcc tcacacaaaa
    16021 aacttgtgtg aggacgtcga tgcgcggtac cacctcaatt atagggaatt tccctatcgc
    16081 tcagtctcgc aataacgaga tgcactgtaa ggtgtgctta ccgaattttt ataatttcaa
    16141 attctaaata gcattcagcc caattttcat cattgccact tatctgtttt cagctaccac
    16201 agactctcta aaaagtttgt atgattactt ttctgaatgg ttaaattata tcatttttaa
    16261 actacttgtc aatagtctat tagaattttt ttgatattca cttttagcat tcactcttga
    16321 aaattatcaa cctgaattac gcaatcctgt cgcaattccg ttgatggtga tatgaatcaa
    16381 tcgttcttga tcactggaca attctccacg acgttggcgt ttaatcaact ctaactgaat
    16441 atagttgaga atattaaagt aaggcatacg gtaatccaga ctagctttta gatatggatt
    16501 gtcagctaag agttcgtcat gtccttcaat agccaagata acgttcttag taacttgcca
    16561 ttcatttaaa atagtctcat agatggcctt aacttgctcg tcttcacaaa gtttagcata
    16621 ttcaaaagca atattcatat ttgattttga caaaaccata tcaacatttg aaagaagcga
    16681 ttggaagaaa ggccaatttt ggtacatatc tcgtaagata gcaatattct ctggattttt
    16741 attgataaat tccttgaagc ttgaaccaac cccgtaccat ccagggaaca taacacgact
    16801 ctgtgaccat gagaataccc aagggatggc acgcaatcca ccgatttcag taatagtctt
    16861 acgagcggct ggacgagaac caatattaaa acttgaaata gccttgattg gacttgaatc
    16921 gaagaaataa tcatagaaat gctcattacc aaagaccaaa tcacggtaga tatcgtaact
    16981 acggtccact acttgatcca taatggcttc ataacgattt ggggtattgg tatcgctctt
    17041 cttctgagta atcatacggt taatagctgc cgatactagc atttcaaggt tatagtaagc
    17101 ggcgtctttg ttaccgtatt tattcccaat tacttcaccc tgctccgtca agcggatacg
    17161 atccttgata gacttgagcg gttgagatgt aatggcttca taggttggcc caccaccacg
    17221 accgacagta ccaccacgac catggaagaa ggtaacctta acgccaaatt catctccaat
    17281 agcagtcaat tgttgttgag ccttgtagag ggtccaacat gatgacaagt aaccgccatc
    17341 tttattactg tcagagtagc caagcatgat ttcttggtag ttatttcgtg agtcaatcca
    17401 ttttttggca aggctaagag aaagatattt tctcattgtt tcctctgaat gatccaagtc
    17461 ttcaattgtt tcaaaaaggg gaacaatctg aacacgcgcc ctttccgtat ccaccagtcc
    17521 tacttctttt aacagaatag ctaattctag catatcagaa aggctggttg catgtgaaat
    17581 gatggtctga cggatgacat catctcccaa cttatctttc aaaacacgag ccgtcttaaa
    17641 aatagctaat tcttttgcta ataattctga tttttctgcg tgagtcgcag aaagaattcg
    17701 gggatcttct tctaattctt tcaagagaag gtcacacttt tcttcttcgc tcaactcgct
    17761 ataacgagaa tgaattcctg ctgatttcaa gagttctgcc acacaggctt catagacgct
    17821 agagtcttgt cgcatatcaa ttgacgctaa gtaaaaacca aatatctcta ctgcctgcaa
    17881 taattccaca aaatcacctg aaatcaagga ctcaccctta ttttctagta gagaatctcg
    17941 aatggcaatc aaatccttgt agaaatcatt ggcggtttca taacgagtcc caacttcttc
    18001 atcctcaatc agataggttt tagttgcctg aatttttgat tgaatatcaa acaaggcacg
    18061 acggtaaagc tctttttcgc ggtaaataga gttatccttg gattgacgag ccatttctct
    18121 gacttgcttg ctgacgttga caatgctagt tgaaagagaa aattcacgat aaagttggta
    18181 aatcttttta tcatagtagt tcatgatgac ttcacactga gtgagtgcag actgcttcaa
    18241 ggtctttgct gtaacaaatg gatttccatc acggtcacca cctatccaca tacccatggt
    18301 gattggttta gcctgtttta aattcagacc atgcgcttgc gctaagcgct tatactccgt
    18361 cgtcaaatga gggacagctt tcaaaaagga gctgttgtaa tattccatag cattcgtgat
    18421 ttcgttagtc acttttaatt ttttctcacg aatcatgtct gtctgcatga taatttcgat
    18481 gtaacgacgc aaatcattgt gccatttatc tttattgatt aaccccaact taacatcacg
    18541 gtatttacgc aaaagactat gaatatgatt tgttaaatcc aacatacttt tgcgttgcac
    18601 ttgtgttgga tgggctgtca aaacagggac aacattcaag tgttctagga tctcaacggc
    18661 attttccttt tctgctacca atttaatcgt tgtagataat ttacctaaat agtcctgatc
    18721 aatattattt tgatgattga tttcataagc taaatccaca tcctctgaaa tattaatcaa
    18781 aagaggtaag atagagaaat agcgtgaaat atagaccatt tcatcatttg ataagctagt
    18841 cactagacgg tttagacctt gataatcttc ctgcgttgat aattctttca actgtattat
    18901 tttttcaaag gtctctgggg caagcatatt tttagtaata tcttccagta attctgttag
    18961 aatcaagact tcttctttca caacactttt attactataa ttttctaatt tttgaagaga
    19021 cataaactat cctttcttta tcctacttca acagaaggtt cattggttga ttttccaatt
    19081 ctcggtacaa cttagcgcgt ttttcactgg catcaatatt taagacaaag gctactgcca
    19141 ctgataagac tagaagacta tttccaccct gggataagaa ggggaaagtc actcctgtag
    19201 atggaatcaa gcccgaaatc cctccgatat tgacaaatac ctgaaccaac atcatccctc
    19261 cgacaccgag tgcaaccatg gcattgaaag gattctccgc tcggataccg accaagataa
    19321 tccgcaaaat catgaaaaac aagagagcta aaataagact ggcaccaaca aagccaaatt
    19381 cttcaatcac gatagaaaag acaaagtctg tatgagcttc tggcaaataa cctcgttttt
    19441 caatcgagtt tccaagacct agaccaaacc aaccgccatt gaccatggca aaataagaat
    19501 tagctaactg gtgacctgca tcagcacgat cggcaaaagg attaaaaaag gcactaaagc
    19561 gcttggctac atagccaaat actggaattt ttgaaaaggt ctcaacaccg attaggctga
    19621 tagtggtcaa gacaaagaca gaagtggcag atacgagcgc cagaatggtt gaaaaccagc
    19681 gataagcgat tccactaact gtatacataa tcaaggaaac caagactaaa atagtcgcat
    19741 ttcctaaatc agggaaaatt cccaaacttc caatcagaac taggagaacg aatcgccaat
    19801 cattaaaagc acggggaagc cattgatttt gagtcaaaac ttgaaaatca taagtagcta
    19861 tttcttcttg ctgtttggag aatcggtgag ctaaatacca aataataatg atttttaagt
    19921 actcagctgg ctgaatagtt actcctgcaa ccgaaatcca accgtatgcc ccgtttacgg
    19981 aaataccaat aaaacgagcc aagaacaata aaagcatttc tattaatata actaaaatga
    20041 ttagtcgctc atttctcaaa aaatctagtc tcaatttata aattaaggca atcagtatca
    20101 aactaacaat ccaaaagatt ccttggtttc gaaccaactg caaggcactc ttgccttctt
    20161 caattaaaat agcactggtg gtcgaataga ccacaatcaa gcccaaaata gataaaagca
    20221 agtagggaat caagatggaa taatttaata agtgcctctt actaatcttc atagcatcac
    20281 cactctacta ggatacagat aaatctgttc caaattccgt tttattttct agttttgatt
    20341 gctattatac cattttttca gaaagaaaaa aactcttacc ttacaatcct tcgaatttta
    20401 ctgtttttac agaattaagg cagaatttga aatcgtaaaa ccattttgaa taagagttgc
    20461 ttcaacccat tgactccgac ggattaagtt gctttcgtga atgccaaaat cagccgcaat
    20521 ttgttcataa gtgctctatt ctcgcatgta ttgaatagtt accataagga gatcgtctag
    20581 gattaatttg ctttttcgtc caccttttgc gcgtttacgt tgataagctg tttttaacac
    20641 agctaacatc tcttcaaaag tcgtgcgctg aacacctaca aggatcttga aacggctatc
    20701 gcttaattgt ttacttgctt catcatccat agttttattg tattgtattt ttgtttcgca
    20761 ggaagtctat tattcctttc gttccaaggt ttttacgctt tttcaagcaa tcctacacac
    20821 tccacgtgat gcgtctgtgg aactcaaaag gttcggggaa ccttttgagg attaattgcg
    20881 tttctctaac aaactcacac attcaacgtg gcatgactga tgaagtcatc ataagaattt
    20941 cacttgctgc tctttctcgg tggcagcctg aacggtcaga agtatcattg tatatcattt
    21001 gtatcatggc atataaagta tcgctctatt ttattgatgg ttttaatatc gctcttatca
    21061 tggcgaacca ttcaaatctg ctccacaaat gaggaaagta ccattttgga ctattcaatt
    21121 gtcaaagaac aaataaaaaa aatcttcgca ttttcacact ctatgaaatt gaggagatta
    21181 ttttctaaag cgaattttat caggaaaatc cgtcaatccc aataggtagt ctgtactgac
    21241 atcgtaaaag tttgagagag ttaccaatat atctgctgtt aacgtatgct caccccgttc
    21301 aattttagca taagctgagt ctgtaaacga aagtatttta gctatttgtt tttgggtcaa
    21361 atcgtgatct tccctcaaat ctctcaaacg tctgtacatc tagctttctc ctgagaaaag
    21421 tataatatat aaaactaaga aatcattcaa agtgtccaaa ctggacattt tgaactaaaa
    21481 ttaatttatt aaacatatct cataagcata tctattatag gtaagacaat attaagaaag
    21541 acggtcaaaa tctattaacc gtctaaagat gttataagct attaaaaaat cagcagtaat
    21601 ccggtaacaa aagtcacata attttgttaa ggaagggatt aatgatgtcc agattactac
    21661 taaccagcaa attgaaaaat ggtcaacatg atatttctaa tgtgaatctc ttactttcag
    21721 aacctaaaag ttgaataata gccaccccct acttatcaat aaaattttcc gttgcattaa
    21781 cagatgtata tagaccactc catggatttc aaagcaatta actagacttt atttgtcaat
    21841 aaccacaaaa ttagattaga aaaatcatta aaaattaatt ggagtccttt gtgatgcttt
    21901 ttcaataaaa gtaatacttc tcaatatttt aactgaacta aagaaatagc ataatggtat
    21961 cttgattgta ttcttctaaa aaggattgcc cttcacattc aactgtgatt gattaaattc
    22021 caaaaatata ttccaaaggc gctctaaatt ctctatatca gctatttttt atcatctatc
    22081 aacttctatc atacctcttc aatagcgtgc taaatattag cgataatatc gtaatagata
    22141 caccaataat aaaaaaatta aaagtattgt taggatttaa aactactgag aaaaaaacag
    22201 tacctagtgg cataaaaaga atagctaccg taaagatgat tccaaatact ctgccaagaa
    22261 actcattatc tacgtctctt tgaacaatag agaaaaattg gatattaaaa atggaaagaa
    22321 atagactaaa taatgctgga gtaaaggcta aaataatgac gttgcggaac atataataga
    22381 tcggcgctgt tagcattaac atcaaacctg aatatgctaa aaagagcatt aaacgtttgc
    22441 ttgacaagga tttattgata aatccactta atatcgcacc aataaagcca ccaatcgctt
    22501 cggctgttaa aaaggttcca tatagcccac ttgaaatact tccaaacatt tgattactgt
    22561 atggcagcaa caaattatag gctgctagga aaaagttaac aagtgctgaa agggcaatta
    22621 tagtgagaat ttgtttatga ctatatacat acgtaaatcc tatttttaaa tcatcaaaga
    22681 ttcctcttat cgtcatattc tcttttgtat ccacctcctc atttacagga gtaatgaaga
    22741 aaattagtga ggcagcaatt aaaaacgata atccatctag taataacaca ccatgtattc
    22801 caagtaactt atataagaaa attgcaatca taggaattgt tactttaatc acagtacttg
    22861 ttgtttctag caatgaatta agttatgata tactgtcctt ttttacaatt tctttcgtaa
    22921 aagctttgta tgatggccct gaaaaagcac tcataaaagc caaaatgaca tttgttatga
    22981 ctatcgcata aaccaaccat ttttcttggg atataaatga aagagttatg caagcaatac
    23041 cacataagat atttgtagta ataataattt ttttccgctt gaaactatct gcaataactc
    23101 caccaaataa attaaataga acacctatca tactttctaa tgattgataa attgcaacca
    23161 ctgatagaga tgttggatta agaccagcaa gaaaggtatt attggcgaaa tcaaacatga
    23221 tatctccgat tcgagatatc atcctactag ctacaatgga tagaatattg tgatgttctt
    23281 ctctaatcat tttattctcc cgaatcagta atcacatatt taaacttttg tgatatgtgc
    23341 ttaagttcat ctaacctttt ctcaaattca caactatttt tgcaattaaa ttggaccaac
    23401 attgaatttt cgactacatt ttcagatact ttatagtaag tatttggttt aataaatatg
    23461 tacacttttt ttgcccaagc caattctttt tcatcaggta cctcgataac cttaccttgc
    23521 tttctatata aagcaaacgt tgctgagata ttagcaggtc tagaaatcac tttagaaaaa
    23581 tttatttttt tcaatccttg tgaattagtc aaaatatccc aatattcttt aattacatca
    23641 actccatgac tatcctcaat taactgggga atatctcccc ctccaaatct ttttccaact
    23701 tcacaaaaga ctattttacc agttgataat tcaaggaacc attcaaaatg aaaaggggtt
    23761 atttcagaat tgatagaaaa aacattcaaa actttgcgac attcttccaa tgctttttct
    23821 atgtattcaa ttttttcact atcattatat aacgaactag tccttacaag ataatatcca
    23881 ctagaactta aggtattgaa caatagttcc tcatattcgt gaacataaaa tcgcttaatc
    23941 tcacttccaa ttgaataacc atcacatgtt atcatgttat cgatatcaat gtattcctct
    24001 ataatatagt ttttttcaaa atacactgaa tcaattttct cgttagggta aacttttttt
    24061 attccattac ttcctgcttc atttctaggt tttaaaattg cagcagaaga tttacaatta
    24121 ttccaaaaaa cacgtaaatc attttctgat tctaaaagcc taaaatacgg ttgatttact
    24181 actccaacta aaaatgaacg catgaagtat ttgtctttaa ataataaatt agacacagag
    24241 tgagtatttt tttctacaaa atgatcattc aaaaaaccta ctatatccat gtcttcctca
    24301 ctcaaggttg taatactctc aacttctgta ttttgactta tccttctaat ttctaagatg
    24361 atatttggta gaataaaatc ttctaaaaaa atgaccttag gtagattatt tccttcagct
    24421 agataatctt catatttttt tctttgaacc tcaggtgcaa taattactac atttctgtta
    24481 tacagatatt ttagtttaac aacccgtgca gaatatctaa ataatactat atgcatgtta
    24541 atcccaatcc tttcaattat tagtcatcat atccatttgg atgtttctgt tgccatttcc
    24601 acgtatcttg gcacattttc ataatatcat accttggctt ccatcccagt agctcttctg
    24661 cttttgaaat atctgcaatt gaaacgtcca tatctcctgc tctccttgaa gttatcttat
    24721 atggaatata cgagcctatg acactctcta agctgtgtag gatttcaaat acactaaaac
    24781 caacaccact tcctaaattg attacttcat ataaaccttc atctgtatta aaaatatact
    24841 ctaatgcttt tctgtgtccg tatgctaaat cgttaacgtg aacatagtcc cttatacaag
    24901 tcccatcagg agtactgtaa tcaactccga atatatttaa atatggtaat tttccaattg
    24961 caacttgtgt aatgtaagga acaagattat tcggaattcc atttggatcc tctcctaaat
    25021 caccactttc atgtgcaccc aatggattaa aatacctcag acaaacaatt ttccaatttg
    25081 aattcgaaat aaacaaatca tttaaaagta cttctatata ctgttttgtt ctcccatacg
    25141 ggtttgaagc ttttaatgga ttagtctcat agaatggcat gataggagta ctttcgtata
    25201 cagtagctga tgaactaaac acaaaattaa ataccttata tttttt
//
LOCUS       DAVMCG010000025        23765 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVMCG010000025 DAVMCG010000000
VERSION     DAVMCG010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.026"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(98..2356)
                     /locus_tag="VYP66_001295"
     CDS             complement(98..2356)
                     /locus_tag="VYP66_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1850844.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VYP66_001296"
     CDS             complement(2585..2815)
                     /locus_tag="VYP66_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1850845.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VYP66_001297"
     CDS             3005..3688
                     /locus_tag="VYP66_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1850846.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VYP66_001298"
     CDS             3688..4422
                     /locus_tag="VYP66_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1850847.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VYP66_001299"
     CDS             4576..5433
                     /locus_tag="VYP66_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1850848.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VYP66_001300"
     CDS             5575..6447
                     /locus_tag="VYP66_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1850849.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPESMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VYP66_001301"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VYP66_001301"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1850850.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VYP66_001302"
     CDS             7426..8637
                     /locus_tag="VYP66_001302"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1850851.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEADIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VYP66_001303"
     CDS             8639..9181
                     /locus_tag="VYP66_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1850852.1"
                     /translation="MTRYALLVRGINVGSKNKVVMAELHQELTNLGLEKVESYINSGN
                     IFFASIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VYP66_001304"
     CDS             9197..10006
                     /locus_tag="VYP66_001304"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1850853.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIRFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKIDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..10877
                     /locus_tag="VYP66_001305"
     CDS             10482..10877
                     /locus_tag="VYP66_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEV1850854.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWDAKNGF"
     gene            10887..11462
                     /locus_tag="VYP66_001306"
     CDS             10887..11462
                     /locus_tag="VYP66_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1850855.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKARFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDGSGKEIE"
     gene            11487..11999
                     /locus_tag="VYP66_001307"
     CDS             11487..11999
                     /locus_tag="VYP66_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1850856.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12653..13363
                     /gene="deoD"
                     /locus_tag="VYP66_001308"
     CDS             12653..13363
                     /gene="deoD"
                     /locus_tag="VYP66_001308"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1850857.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13386..13910)
                     /locus_tag="VYP66_001309"
     CDS             complement(13386..13910)
                     /locus_tag="VYP66_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1850858.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13963..14199)
                     /locus_tag="VYP66_001310"
     CDS             complement(13963..14199)
                     /locus_tag="VYP66_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1850859.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSTKLAK"
     gene            complement(14267..15187)
                     /locus_tag="VYP66_001311"
     CDS             complement(14267..15187)
                     /locus_tag="VYP66_001311"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1850860.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15377..15780
                     /locus_tag="VYP66_001312"
                     /pseudo
     CDS             15377..15780
                     /locus_tag="VYP66_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15996..16577
                     /locus_tag="VYP66_001313"
     CDS             15996..16577
                     /locus_tag="VYP66_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1850861.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLAQRNAEKNNA
                     KATIFQSNIYARVQGRFDHVISNPPIRAGKQVVHEIIEKSKDFLEIGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16574..17851
                     /locus_tag="VYP66_001314"
     CDS             16574..17851
                     /locus_tag="VYP66_001314"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1850862.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDVLDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17869..18531
                     /gene="deoC"
                     /locus_tag="VYP66_001315"
     CDS             17869..18531
                     /gene="deoC"
                     /locus_tag="VYP66_001315"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1850863.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18518..18907
                     /locus_tag="VYP66_001316"
     CDS             18518..18907
                     /locus_tag="VYP66_001316"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1850864.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            18997..20049
                     /locus_tag="VYP66_001317"
     CDS             18997..20049
                     /locus_tag="VYP66_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1850865.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20193..21728
                     /locus_tag="VYP66_001318"
     CDS             20193..21728
                     /locus_tag="VYP66_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850866.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SAGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQGLGVLMAGGNLGKEK
                     SDV"
     gene            21721..22779
                     /locus_tag="VYP66_001319"
     CDS             21721..22779
                     /locus_tag="VYP66_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850867.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22782..23738
                     /locus_tag="VYP66_001320"
     CDS             22782..23738
                     /locus_tag="VYP66_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850868.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         6900 a         4302 c         5419 g         7144 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttatca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggggcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatctgtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag cttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gatggaaaat attaccttgt cacctatcaa gactaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc aacaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaggaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac tattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa tcgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttattgta taataaaagt gagaggaaaa aaggatgaaa
     5581 gtgattaatc aaaccttatt agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagtcta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagttg tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagag
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaattgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgca gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaatcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aattgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctgatat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt agtaagaata aggtcgtcat
     8701 ggcggagctt catcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttctttg cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcaga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatggggg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagattgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtgtgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggaggctacc
    10741 tagctcagat tgcagcggtt gaagattacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttgggatg
    10861 ctaagaatgg tttctgagat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aataatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagcgc gattctttaa gaaacaggct ctacctcaat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa caggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa acttccaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacgg ttctggtaaa gaaattgagt
    11461 gaaaacgtat aatatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaagataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgacagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 tagaactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaagaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaacaaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aaggaattga ccccacccta aaagtagtgg gaaaaagata
    12421 gttggtctag cgagcatcgc tcactgcgcc caactcctat tttcccttcg ctttttgatg
    12481 ggtttggtat ctttctcaat ataaaatata aaataaagaa aggtagagcg tgtgttttga
    12541 tttgaacacg agcggaaaac tcggaaaata gataatctga ctgaaaaatc aggatttctc
    12601 gtcaggttcc taattttcag tcgttttctt ctcgctcttt gtatcataaa ttatgtctat
    12661 ccatattgct gctcagcagg gtgaaattgc tgataaaatt cttcttcctg gggatcctct
    12721 tcgtgctaag tttattgcgg agaatttcct tggtgatgct gtttgtttta acgaagtgcg
    12781 taacatgttt ggttacactg gtacttacaa gggtcaccgt gtatctgtca tgggaactgg
    12841 gatgggaatg ccatctattt cgatttatgc gcgtgagtta atcgtagact acggtgtgaa
    12901 gaaattgatt cgtgtgggaa ctgcaggttc tttgaatgaa gaggttcatg ttcgtgaatt
    12961 agttttggcg caggcggctg caaccaactc aaacatcgtt cgtaatgact ggccacagta
    13021 cgattttcca caaattgcta gctttgattt gcttgataaa gcctaccata tcgccaaaga
    13081 acttggtatg actactcacg ttgggaacgt tttgtcatct gatgtctttt actcaaatta
    13141 ctttgaaaag aatatcgagc ttggtaaatg gggagtcaag gctgtggaaa tggaagcagc
    13201 agctctttac tatcttgctg cccaatacca tgttgatgcg ctagctatca tgaccatctc
    13261 tgatagcttg gtcaatccag acgaagacac aactgcagaa gaacgtcaaa ataccttcac
    13321 tgatatgatg aaggttggtt tggaaacctt gattgcagaa taattatagc caaaaaggaa
    13381 gccctttatg aattgtagga cttccttttc ttatccagaa attgatctag ctctctctga
    13441 tttcgaagaa tagtgacttt atgtgaatat tcttggcaaa gtttttggta attttctttt
    13501 tgagttttgc tacgcccatc ccaaagaatc catctgataa actcccagtc aaagcgttca
    13561 gggcaatctg ccgccatact ttctctgact tttccacggt atttaagata acgcttaaag
    13621 gctctaaaga gacaggtcaa tggcaaaaaa ttgagaaaga tgatttggtc agcttcttgc
    13681 attcgttctt ggtagtagca ccaagaataa ttaccatcga tgacccaagc tttatgcttg
    13741 gtgagaaagt tttttatctc ggttaacatc cattcgcagt cactgtcttg ccaaccaggt
    13801 tgaaattgga gtgtgtccat gtgcagtttt ggaatggagt agtagttaga taacttttct
    13861 gctagagttg acttaccaga accagaatat ccgataattg tgattttcat tttctacctt
    13921 ttcctatttg gagacaaaaa aacagcctct atggactgtt tcttatttag caagtttagt
    13981 tgaaagacga gctttatcgc ggcttgcttt gtttttgtga atcaaacctt tagtttctgc
    14041 tttatcgata gctgagctag cagcacggaa aagttcttca gatgggtttg cttcgaaagc
    14101 ttttatagca gtacgcatag ctgatttttg agctgagttc ttttcgtttt gtttaacgtt
    14161 caattcagcg cgtttgatag ctgatttaat gtttgccaat gttcttacct ccatatttac
    14221 taactatacc attatatatg aaaacttacg ttttgacaag ggaaaattac ttttttaagt
    14281 aaatttcatc gatttcatgg ttcttgcttt tatgaagaat cacttctgca cgatttctgg
    14341 ttggttcaat ataattttgc agatttgtga gattgatact gatccagacc tgatgggcaa
    14401 aggactccac ttccccaatc ggcatctgag taaaacgata atagtagcta tcagggtcgt
    14461 tttgggctag gctcagcatc ttcaagaaac ggtccagata ccaactttca atatcatcca
    14521 ctccagcatc tacatagatg gaaaagtcaa agaagtcagt gatatagaga cgatcgtttt
    14581 gtggattttg aaagacatta attccctcaa caattacaaa atcagcagct ttgacacttt
    14641 gtttcttttc gggtacgatg tcgtaaactt catgagaata gacaggaata tctacatctt
    14701 gtccattttt gatgcggtcc aagaagttga gaagagcttc catatcatag ctttcaggaa
    14761 atcctttacg atttaaaatc ccctgctcaa tcaaggtttg attgggatag agaaaaccat
    14821 cagttgtaac caactcaacc gtagcatctg taaacgtacg ggacagtagg atttgaagta
    14881 ggcgactggt tgtggatttt ccaacggcaa cactcccaga aaccccaata ataaaaggtt
    14941 gagatttact ttcacgttgg aggaaaattc cttttgaaaa ggctaaatct tccttagttc
    15001 gcttgtaaat ctgaatcaga tgagccaagg ggagatagat atctgtaacg tcttggagac
    15061 tgatttggtc attaaaactc ttgatagatt ccaattcttc ttctgtcaaa ggaggtgttg
    15121 tctttcgatg taaagattgc caagtctggc ggctgatttt ttcaaaatgt aaaaattcgt
    15181 tggtcatttg ttttccccta gatattttgt ttatcatacc ataaaaagct aaaaaaataa
    15241 agcggtttct tgaatgtggt aagtcaatgg tatatagtat aagtgatcaa tttattgatg
    15301 aaataggaga tagattctac tgatttataa gcttataaag ggggcttttt agttcacaac
    15361 ttataggagg tgtactatga aaatcttaaa acgttacata ttggaactct gttttatttt
    15421 aagttttgct ttacctttta taaaaggaac caatgcagat aatggtagat gctttgtgga
    15481 aacctattac ggttttactt ttttgatgga acatgctatt gtaacagctg tctttatttg
    15541 ttcgttctta attgctttct tactaaaaaa cgatggacga aatggattgc tgcgggtagt
    15601 tattgctttt tagtcctacg gattgcgaca gagggttatt tcttccacat gtcactagaa
    15661 gatttgatac gactttggac aagtttggaa atcctgacac aaacgtatca gttgggcttt
    15721 tatctaaaca ttttgttagg aattttgttg ataataaagt attttaaggt taagcaatag
    15781 aaataataat ctgcctgatt atagatgata aactttttgt ttttatctgg actgtgatat
    15841 ttatagttct aaatggttta ttatttataa gtgttgaaag agattgaaga aaatggcttc
    15901 gtgacttgct ttcttcggtc tttttcgttt tattatcaat ttgtaaacga tttacaattt
    15961 gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta ctatgcagaa aatcctgacg
    16021 ctgctcacga cattcatgag ttgagagtgg acttgttggg agaaaaaatg acttttttga
    16081 cagatgcggg tgtttttagc aagaaaatgg ttgactttgg aagtcaactc ttgctcaagt
    16141 gtctggatgt caaccaagga gagacagtcc tagatgtagg ctgtggttat ggtccattag
    16201 gtttgtcctt ggtcaaggtt tacggagttc aggcgaccat ggttgatatt aacactcgtg
    16261 ccctggattt agctcagaga aatgctgaaa aaaataatgc aaaagcgacg atatttcaat
    16321 ctaatattta tgcaagagtt caagggcgat ttgaccatgt catttccaat cctcctatcc
    16381 gtgcgggcaa gcaagtcgtt catgaaatca tcgagaaaag taaagatttc ttggaaattg
    16441 gtggagattt gaccatcgtc atccagaaaa aacaaggagc tccaagtgcc aaatctaaga
    16501 tggaagatgt gtttggcaat tgtgaaatcc ttaaaaaaga caagggatac tatatcctta
    16561 gaagtgtgaa agaatgagag cagttgattt aatccaaaaa aaacgagacg gtcaagaact
    16621 gacttcaagt gaaattgaat ggctgataga aggctatgta tcaggaactg ttcctgatta
    16681 tcagatgtct gcctttgcta tggctgttta ttttaaagga atgacgactc gagaaatctc
    16741 tgatttaacg atgaatatgg ttaagactgg gcaagagttt gacctgtcag ccattgatgg
    16801 tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat aaggtaacct tgattttagc
    16861 tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg agtggtcgtg gtcttggcca
    16921 tacaggcgga acaattgata aattggagtc cattaggggc tatcaagtag aacgtagtca
    16981 agaggatttt attcgtcagg ttcaggatat tggagtatct gtcattgggc aatcagacca
    17041 gctggtcaaa gcagataagc ttctctatgc ccttcgtgat gtgaccgcaa ctgtcgacac
    17101 gattcctttg attgcgagtt cggtgatgag caagaaaatt gcggcagggg cggatgctat
    17161 tttgctagac gtgactgtcg gtgagggtgc cttcatgaag acggttgatg aggcgcgtga
    17221 gttggctcaa actatggtag atcttggtaa ggttgttgga cggaagacag tagcagtgat
    17281 tacggatatg agccagcctt tgggacgagc gattggaaat cgtctggaaa tccttgaagc
    17341 attggagatt ttgcaaggtc aaggacgtca ggatattacc cactttattt gtgaattggc
    17401 tcaaattatg cttggtttgg caaatgttaa caaaactgtt gaagaagttc gccaacatct
    17461 tgaaaatggt caagcactgg ctaagtttga ggaaatggtg caagcccaag gtggagactt
    17521 ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg gaaatccctg ctcaggaaac
    17581 gggtgtcatt tcagctcttc cagctatgga ctttggtctt tatgccatga ggctgggtgc
    17641 tggtcgtgca gttaagtctg atgtcttgga ctatgaaaca ggaattgttt ttgaaaagaa
    17701 gattggagac tccgttcaaa agggtgaaat tgttgcaaaa gtatacacaa atgaaaaaat
    17761 tccacctcaa ctagttacag atttccaaaa atgtgttaaa ataagtgatg aagtgaaaaa
    17821 aatccgtgaa attgtagaaa tcatctccta aatggaggga aaaccgaaat gaaattaaat
    17881 aaatatatag atcatacgct tttaaaacaa gatgcaaaga aaaaacaaat tgatagtttg
    17941 ttgtctgagg ctagagagta tggctttgcc agtgtttgcg ttaatccgac ctgggttgaa
    18001 catgctaaaa aaggacttga aggcacagat gttaaggttt gcacagtagt aggtttcccc
    18061 ttgggagcaa caacttcaac tgtgaaagct tttgaaacaa aagaagctat ccaaaatggg
    18121 gctgatgaga ttgacatggt gatcaatgtt ggagctctca aatcaggtaa tttagccttg
    18181 gttgagtcag atattcgcgc agtagtggaa gcaagtggtg ataagttagt gaaagtcatt
    18241 attgaagctt gccttctgac agaccaagaa aaaattgttg tttgccaatt ggcccaaaaa
    18301 gctggggctg actttgttaa aacatctact ggcttttcaa ctggtggtgc tacgatagca
    18361 gatgttagat taatgcgtga aacagttgga tctgatatgg gagtcaaggc tgctggtgga
    18421 gctcgttctt atgcagatgc tcttgccttt gtcgaagcag gtgcgacccg tatcggaacg
    18481 tcagctgggg tagctatttt aaaaggagaa ttggcagatg gcgactactg agttgattga
    18541 actggcaatt gaaaccagca aacatgccta tgtcccctat tctcactttc ctatcggagc
    18601 agttttagta gccaaagacg gaagtgttta cacgggagtg aatatcgaaa atgctagcta
    18661 tcctttgacc aattgcggtg agagaacagc tgtttttaag gctatatctg aaggccaaag
    18721 agaattttca gaattgattg tctatggtca aactgaaaaa ccgatctcgc catgtggtgc
    18781 ttgtcgccaa gtaatggtcg aattttttga acaagattta aaagtgacct tagtcgcaaa
    18841 agataaatcg acggtcgaga tgacggtcgg ggaattactt ccatactctt ttacagactt
    18901 aaactagtct gagtcgctct ctgagtggca cggtccttgt ggccaaccaa tccatacttg
    18961 caacatcgtt gcacatctta tttaggaggt tcagtaatga acaagaaaca atggctaggc
    19021 cttggtctag ttgcagtggc agcagttgga cttgctgcat gtggtaaccg ctcttctcgt
    19081 aacgcagctt catcttctga tgtgaagaca aaagcagcaa tcgtcactga tactggtggt
    19141 gttgatgaca aatcattcaa ccaatcagct tgggaaggtt tgcaggcttg gggtaaagaa
    19201 cacaatcttt caaaagataa cggtttcact tacttccaat caacaagtga agctgactac
    19261 gctaacaact tgcaacaagc ggctggaagt tacaacctaa tctttggtgt tggttttgcc
    19321 cttcataatg cagttgaaga agcagctaaa gaacacactg acttgaacta tgtcttgatt
    19381 gatgatgtga ttaaagacca aaaaaatgtt gctagcgtaa ctttcgctga taatgagtca
    19441 ggttaccttg caggtgtggc tgcagcaaaa acaactaaga caaaacaagt tggttttgta
    19501 ggtggtatcg aatctgaagt tatctctcgt tttgaggcag gattcaaggc tggtgttgcg
    19561 tcagtagacc catctatcaa agtccaagtt gactacgctg gttcatttgg tgatgcggct
    19621 aaaggtaaaa caattgcagc cgcacaatac gcagccggtg cagatattgt ttaccaagta
    19681 gctggtggta caggtgcagg tgtctttgca gaggcaaaat ctctcaacga aagccgtcct
    19741 gaaaatgaaa aagtttgggt tatcggtgtt gaccgtgacc aagaagcaga aggtaaatac
    19801 acttctaaag atggcaaaga atcaaacttt gttcttgtat ctactttgaa acaagttggt
    19861 acaactgtaa aagatatttc taacaaggca gaaaaaggag aattccctgg cggtcaagtg
    19921 atcgtttact cattgaagga taaaggggtt gacttggcag taacaaacct ttcagaagaa
    19981 ggtaaaaaag ctgtcgaaga tgcaaaagct aaaatccttg atggaagcgt aaaagttcct
    20041 gaaaaataat ggatggaagt catttcttag gaagcggcca agggccgctt ttttaagagt
    20101 tgagacaaag tcattttgtc tcagtaaagc ttgctactag acaaactagc aagttttatt
    20161 gaaataaaat aagactctga aaggaagagc acatggcaca cgaaaatgtc attgagatgc
    20221 gtgatattac caaggtgttt ggtggatttg ttgccaacga caaaatcaac ttgcacctac
    20281 gaaaaggtga aattcatgca cttttaggag aaaatggggc tggtaagtcc acgctaatga
    20341 acatgttagc aggccttctt gaaccaacta gtggtgaaat cgcggtcaac ggtcaagttg
    20401 tcaatctcga ctccccatct aaagcagcta gcttgggaat cgggatggtt caccagcact
    20461 ttatgttggt tgaagccttc acagtggctg aaaacatcat tttaggtagt gaattgacta
    20521 aaaatggtgt gctagatatc gctggagcta gcaaagaaat caaggctctt tctgaacgtt
    20581 atggcttagc tgttgaccct tctgccaagg tagcagatat ctcagttgga gcccaacaac
    20641 gtgtagaaat tttaaaaaca ctttatcggg gggctgatat ccttatcttt gacgaaccaa
    20701 cggctgtttt gactccatca gaaattgatg agttgatggc tattatgaaa aatcttgtca
    20761 aagaaggaaa atcaattatc ttgattaccc acaaattgga tgaaattcgc gcagtttctg
    20821 accgtgttac agttatccgt cgtgggaaat caattgaaac cgttgaaatt gcaggggcta
    20881 ccaatgctga tttggcggaa atgatggtag gacgttctgt ttcctttaaa acagagaagc
    20941 aagcctctaa accaaaagaa gtggttttgt ctatcaaaga tttggtggtc aatgaaaacc
    21001 gtggtgttcc agctgttaaa aatctgtcct tggatgttcg tgctggagag attgttggta
    21061 ttgcggggat tgatggaaat ggtcagtctg aactgattca agccattaca ggtcttcgta
    21121 aggttgaatc tggtagcatt gagctaaaag gagattcaat tgtaggcttg cacccacgtc
    21181 agattacaga actaagtgct gggcacgttc cagaagaccg tcaccgtgat ggcttgattt
    21241 tggaaatgat gatatctgaa aatattgccc ttcaaaccta ctataaagaa ccacatagta
    21301 aaaatggaat tttgaattat tcaaatatta cttcttatgc taaaaagctg atggaagagt
    21361 ttgatgttcg cgctgccagt gaattagttc ctgcagctgc actctcagga ggaaatcaac
    21421 aaaaagcaat tattgctcgt gaaattgatc gagatcctga tctccttatc gttagccagc
    21481 caactcgtgg gttggatgtc ggtgccattg agtatatcca caaacgcttg attgaagagc
    21541 gtgataatgg caaggctgtc cttgttgtca gctttgaatt ggatgagatt ttaaacgtct
    21601 cagaccgtat tgccgttatc cacgatggta agattcaagg tattgtatca ccagaaacaa
    21661 ccaataaaca aggacttggt gtcttgatgg ctggtggaaa cttgggaaag gagaagagtg
    21721 atgtctaaaa aattacaaca aatttcggtt cccttgattt ctgtattcct aggaatttta
    21781 ctcggagcca ttgtcatgtg gatcttcggt tatgatgcta tttggggcta cgaagaattg
    21841 ttctatacag cctttggcag tctgcgtggg attggagaaa tcttccgtgc tatgggtcct
    21901 ctggtcttga ttggtcttgg ttttgcggtt gccagtcgag ctggtttctt taacgtcgga
    21961 cttcctggtc aggctttggc aggttggatt ctcagtggtt ggtttgccct gtcgcatcca
    22021 gatatgcccc gtcccttgat gattctagca accatcgtga ttgccttgat tgctggtggg
    22081 attgtcggag cgattccagg tattcttagg gcctatctag ggacgtcaga ggttattgta
    22141 accatcatga tgaactacat tgtcttgtat gtagggaatg cctttatcca tgctttccct
    22201 aaagacttca tgcaaagtac agattcgacc attcgtgttg gggctaatgc aacctatcag
    22261 acaccttggt tagctgagtt gactggtaac tcacggatga atattggtat tttctttgcc
    22321 atcattgccg ttgcagttat ttggttcatg ctcaagaaaa caactcttgg ttttgaaatc
    22381 cgtgcagttg gtcttaatcc acatgcttca gaatatgctg gtatttctgc caagcggact
    22441 attatcctat ctatgattat ttcaggtgcc ttggcaggtc ttggtggagc tgttgaaggt
    22501 ttgggaacct tccagaacgt ctatgttcaa ggttcgtcat tagctatcgg atttaacgga
    22561 atggcggtta gtttgcttgc ggccaactca ccaattggta tactctttgc agccttccta
    22621 tttggcgttc tccaagttgg ggctcctggt atgaatgcgg cgcaggtacc atctgagctt
    22681 gtcagcattg taacagcgtc tattatcttc tttgtcagtg ttcattacct tatcgaacgc
    22741 tttgtcaaac cgaaaaaaca agttaaagga ggtaagtaaa gatgtctatt ataaccttgc
    22801 tccccctctt ggtgtcttct atgctgattt actcagcacc tctcatcttt acaagtatcg
    22861 gtggtgtttt ctctgaacgt ggtggtgtgg taaacgttgg ccttgaagga attatggtta
    22921 tgggtgcctt ttctggagtt gtctttaacc ttgaatttgc agaacaattt ggagcagcaa
    22981 ctccatggct atccttgctt gtagcaggat tggttggtag tgttttctct atcatccacg
    23041 cagcagcgac ggttcatttc cgtgcagacc atgttgtcag cggtacggta ttgaacttga
    23101 tggcgcctgc cttggctgtt ttcttagtta aagttcttta taacaaagga caaaccgaca
    23161 acctaagtca aacttttgga cgctttgatt tcccagtctt ggcaaatatc ccagtgattg
    23221 gtgatatctt cttcaagtca actagtctac ttggttatct ggcgattgcc ttctcattcc
    23281 ttgcttggtt tattctcttt aagactcaat ttggtcttcg tctccgctct gtcggtgaac
    23341 atcctcaagc agcggatacc ttgggaatca acgtctacaa gatgagatat ttaggggtta
    23401 ttatttcagg ttttctaggt ggaattggcg gagcgattta tgcgcaatca atctcagtta
    23461 acttctcagt gacaactatt gttggacctg gatttatcgc ccttgctgcg atgatctttg
    23521 ggaaatggaa tccaatcggt gctatgcttt ctagtctctt ctttggactt tcacaaagtt
    23581 tggctgttat cggttctcaa ttgccgttcc tacaaggagt gccagcggtt tatcttcaaa
    23641 ttgcacctta tgttttgaca attcttgtct tagcagcctt ctttggaaaa gcagtcgcac
    23701 caaaagcaga tggtatcaac tacatcaaat caaaataagc atacaaaaaa acgtcagtcc
    23761 aatga
//
LOCUS       DAVMCG010000026        22814 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVMCG010000026 DAVMCG010000000
VERSION     DAVMCG010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.027"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(1..597)
                     /locus_tag="VYP66_001321"
                     /pseudo
     CDS             complement(1..597)
                     /locus_tag="VYP66_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            complement(981..2177)
                     /gene="tuf"
                     /locus_tag="VYP66_001322"
     CDS             complement(981..2177)
                     /gene="tuf"
                     /locus_tag="VYP66_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1850869.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(3088..3957)
                     /locus_tag="VYP66_001323"
     CDS             complement(3088..3957)
                     /locus_tag="VYP66_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1850870.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(4180..4701)
                     /locus_tag="VYP66_001324"
     CDS             complement(4180..4701)
                     /locus_tag="VYP66_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1850871.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVVSGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPDPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4659..5765)
                     /locus_tag="VYP66_001325"
     CDS             complement(4659..5765)
                     /locus_tag="VYP66_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1850872.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5876..6130)
                     /locus_tag="VYP66_001326"
     CDS             complement(5876..6130)
                     /locus_tag="VYP66_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850873.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6488..7021)
                     /locus_tag="VYP66_001327"
     CDS             complement(6488..7021)
                     /locus_tag="VYP66_001327"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1850874.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(7008..7334)
                     /locus_tag="VYP66_001328"
     CDS             complement(7008..7334)
                     /locus_tag="VYP66_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1850875.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            7568..9286
                     /locus_tag="VYP66_001329"
     CDS             7568..9286
                     /locus_tag="VYP66_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1850876.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLVDGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9397..9744
                     /locus_tag="VYP66_001330"
     CDS             9397..9744
                     /locus_tag="VYP66_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1850877.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(10022..10858)
                     /locus_tag="VYP66_001331"
     CDS             complement(10022..10858)
                     /locus_tag="VYP66_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1850878.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10871..11500)
                     /locus_tag="VYP66_001332"
     CDS             complement(10871..11500)
                     /locus_tag="VYP66_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1850879.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11510..12151)
                     /locus_tag="VYP66_001333"
     CDS             complement(11510..12151)
                     /locus_tag="VYP66_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1850880.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12297..13526)
                     /locus_tag="VYP66_001334"
     CDS             complement(12297..13526)
                     /locus_tag="VYP66_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1850881.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13516..14682)
                     /locus_tag="VYP66_001335"
     CDS             complement(13516..14682)
                     /locus_tag="VYP66_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1850882.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14826..15839
                     /locus_tag="VYP66_001336"
     CDS             14826..15839
                     /locus_tag="VYP66_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1850883.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15884..16303)
                     /locus_tag="VYP66_001337"
     CDS             complement(15884..16303)
                     /locus_tag="VYP66_001337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1850884.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16314..17720)
                     /gene="atpD"
                     /locus_tag="VYP66_001338"
     CDS             complement(16314..17720)
                     /gene="atpD"
                     /locus_tag="VYP66_001338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1850885.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17806..18684)
                     /locus_tag="VYP66_001339"
     CDS             complement(17806..18684)
                     /locus_tag="VYP66_001339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1850886.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18700..20205)
                     /locus_tag="VYP66_001340"
     CDS             complement(18700..20205)
                     /locus_tag="VYP66_001340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1850887.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(20220..20756)
                     /locus_tag="VYP66_001341"
     CDS             complement(20220..20756)
                     /locus_tag="VYP66_001341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1850888.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20756..21250)
                     /gene="atpF"
                     /locus_tag="VYP66_001342"
     CDS             complement(20756..21250)
                     /gene="atpF"
                     /locus_tag="VYP66_001342"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1850889.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21264..21980)
                     /gene="atpB"
                     /locus_tag="VYP66_001343"
     CDS             complement(21264..21980)
                     /gene="atpB"
                     /locus_tag="VYP66_001343"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1850890.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(22015..22215)
                     /locus_tag="VYP66_001344"
     CDS             complement(22015..22215)
                     /locus_tag="VYP66_001344"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1850891.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(22290..>22814)
                     /locus_tag="VYP66_001345"
     CDS             complement(22290..>22814)
                     /locus_tag="VYP66_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1850892.1"
                     /translation="IEQRLEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQI
                     IRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLSNVFSEEHIYYAHPYASWE
                     RGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNL
                     KFSKMEIIFIKRFQ"
BASE COUNT         6781 a         4910 c         4155 g         6968 t
ORIGIN      
        1 agcccaacaa gatcccagtt tactgattct accgaaacca gcctcatctt ggtacatcaa
       61 gcgaacctta cgaaaacgtc tactatattt aaaacgcttt cttgtcttct tgaattgaga
      121 ttttattttt agacgcgaca atggtttgag cgtctgcttt cttaggatgt tctggacgtg
      181 gcataatatt tcgccaacca tggcgcttca acagttgata gaaggcatca cgtgtgtagg
      241 aacgacctaa ctccttttta taagcctgaa ataaggcatc aattgtaaca aattctcctg
      301 cctctgcagc cttcaaatgg cgggcaagaa agactttctc ttcctcaact gtcatatatg
      361 catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac tcctcatatt
      421 tttttacatt tcgccaaatc attgtttgat tacagtctaa aagttctata atctctttat
      481 aagatttgcc catatcagac gaaatagaac gatttgaaga cgtttatgat atttagctgt
      541 acgagagtct tttaaaagtg ttttgatggt ttggatttct tctttaattg atttcatatt
      601 actattgtat aatgcttttt gattttagtc tagtattata ctcttcgaaa atctcttcaa
      661 accgcgtcag cttcgccttg tcgtatagat gttactgact tcgtcagttc tatctacaac
      721 ctaaaaacag tgttttgagc agtctgtagc taactttcta tagtaaaatg aaataagaac
      781 aagacaaatc gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtaaatgtgt
      841 actattctag tttcaatata ttatagtttg ctctttgatt ttcattgagt attagttcaa
      901 tatctaaaaa aagaaccttg ccaagcaaga ttcttttagt gtctgactta aataattgtt
      961 cttctgggaa ctaaatcgaa ttaagcttcg atttctgtaa ccatacctga accaacagta
     1021 cgtccaccct cacggataga gaatgtagta ccttgttcta cggcgattgg gtgaatcaac
     1081 tcaacgtcga ttgtcacgtt atcaccaggc attaccattt cagtacctgc tggaagttcg
     1141 attgaacctg taacgtcagt agtacggaag tagaattgtg gacggtagtt gttgaagaat
     1201 ggagtgtgac gtccaccttc ttctttagta aggatgtaga cttcaccttt gaatttagtg
     1261 tgtgggttga ttgaacctgg tttagcgata acttgtccac gttcgatttc atcacgttga
     1321 acaccacgaa gaaggacacc tacgttatct ccagcaagac cttcgtcaag ttgtttacgg
     1381 aacatttcaa caccagtaac aactgctttt tgagtttctt ctttgatacc aacgatttcg
     1441 atttcgtcgt tgactttaac gataccacgg tcgatacgtc ctgaagcaac tgtaccacgt
     1501 ccagtgattg agaatacgtc ctcgactgga agaagcaatg gtttgtcagt gtcacgttct
     1561 ggttctggga tatactcatc aactgtgttc atcaattcca taacgatgtc ttcgtattta
     1621 gagtcacctt caagagcttt aagtgctgaa ccttggataa ctggaagatc gtcacctggg
     1681 aagtcgtatt ctgacaatag gtcacggatt tccatttcaa ccaattcaag caattcttcg
     1741 tcgtcaacca agtcaacttt gttcatgaag acgataaggt gtttaacacc aacctgacgt
     1801 gaaagaagga tgtgctcacg agtttgtggc attggtccgt cagttgaagc tactacaagg
     1861 atagctccgt ccatttgagc agcaccagtg atcatgtttt taacgtagtc cgcgtgtcct
     1921 ggagcgtcga tgtgagcgta gtgacgtttt tcagtttcgt actcaacgtg cgcagtgttg
     1981 atagtgatac cgcgttcgcg ttcttctgga gcagcatcga tagacgcata gtctttaggt
     2041 tggttaactg atgaaggcaa gcgacgtgcc aaaacagttg tgatagctgc agttagggta
     2101 gttttaccgt ggtcaacgtg tccgatagta ccaatgttaa cgtgtggttt actacgatcg
     2161 tatttttctt ttgccatttg agtaaaagcc tccaataaaa tatattttat agatagacag
     2221 taggcaatac agtctaactt tccttactat tttatcaaat ttcagctaaa ttgcaagtgt
     2281 tttacaacgt ttttgtgaat tattcttgat aaaaatttaa ctaactaata gaaagtacta
     2341 aatagactta tccttcaagg agttttcagc attatccatc cactcacttg ctgaaaatgt
     2401 aaacagtctc tggtttatat agtaaaatga aacaagaata gggcaaatcg atcaggacag
     2461 tcaaatcgat ttctaacaat gttttagaag ttgaggtgta ctattctagt ttcaatctac
     2521 tatacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcttagt ttgccctttg
     2581 attttcattg agtataaaat tgcagataaa acgataacaa tcataggact cagcagagtc
     2641 aatgtaggtc gaagaatagc cctcctaatc gcttatttta tagcaaaatg aaatagaaac
     2701 tgaacatttt gttgaggaag gtaaatcaat tcctcacaat gtttgagaaa gaagggagga
     2761 ctattccaac ttcaacccac tataaagcag acttacaaga tagggaaccc atctccgata
     2821 atatatagta gaatgaaaac tgcacaattt gattggagaa ttcaaaccaa tttctaacaa
     2881 tgttttagaa acaagggtct attatttcaa ctgcaaccta ctatagccca ttgaagctgg
     2941 aatagcccac tgagacttct aaaccactgc tggagaggag tttgtttaga gtttctttca
     3001 tttccctaaa aaatcaaaaa gagagaacca gtctgatcct ctcttactta tagatggtgc
     3061 tcactcaaat gttaaaggag ctatttctta gagataaagg aatttgaata cagctactgc
     3121 cgcaattgct gctgcgatag gtgctactac tggtacccaa gaataccacc attttgaatc
     3181 gcctttatgc tcaccaagaa ctgattttgg aaggaaagca tgaaggagac gtggtcccaa
     3241 gtcacgggct gggttcaagg caggtcctgt aggtcctcca agtgatgtta ccaaagccat
     3301 aacgaggaat ccaagtgcca agtgagccac agaaagtcct gaagcagtgt gtggagccac
     3361 ctgtgcttta atagccaagt cagaaaaatc aactgtttgt cctgcttcta ttgccttttg
     3421 tttcatgaat tgaagcactt cagcaccaaa gaagttttta gtcaaaccaa gagctgcaaa
     3481 gaacaaaaca aatgaaccaa caaactcatt aatcaaacca ttgacagttg ctgcatagcg
     3541 actttctttt gtaccatggt caatacttga aatagttgag aaagttccca agatgttatt
     3601 tggtttttca gttttcaagt agaatggacg gtatgttgcc acaactaagg cttggccaaa
     3661 gatagctccc aagacttgcg cgataatgta aggtaccact tgtgcccaag ggaaaagacc
     3721 gctaactgca agccctagag tgaaagcagg gttgatgtga ttcccagata cgttaccaaa
     3781 catcaaggct gggatcataa cccccatacc ataaccaaca gcgatgacga tccagccact
     3841 ttggtgacct ttcgtacctt taagttcaac gttggcaact gcaccattcc caagaatgat
     3901 caaaatggca gttcccaaaa attcagtggc atacttcagt gcccatgtga aatccatttg
     3961 ctagattctc cttaaaattt tttagatatt ccttatttta tcaattttta ccctatttag
     4021 caactgattt ctggaaatat ttttaaaaaa ataggattca tagtttccca gttcaacgta
     4081 cttgtaagcg tttttattct tcacgaaaga cctcattctc aaaaccagga aaaagcccac
     4141 atctgtgatc ttttccttgt tcctagattc taaaatctat tatttttcat cttctttttt
     4201 cttgaagaat cctaatccta gaccagctaa caaggtcatg ataccagcac tagccaaggt
     4261 agcattagct tctgtacctg tgtttggcaa ttcctctctc ttacctgtct cataagtcgg
     4321 aacttctggg tctggattca ctggagtttc agtttttgga gtacctgggt ctggagttgg
     4381 tttatctggt gttgataaac ggtcatacct taccgttatt tctttatcac tagagtctga
     4441 cgtaacttct tgtgattcaa ctgttggaat atctggatct ttgtacttgt caatcttacc
     4501 agatacaacc tcgtcccagt ttcctgttgt ccattcaccg taggttacaa ctcccgtgac
     4561 cttgttctca gtttttgtac ggcttaaggt tacaggttga acaacatctt cttttacatt
     4621 ttggttcgta actttatcaa cgtaatgaat gatacgcgtt atagtcttcg tctcagtaga
     4681 ggttgctgtt ttgggaacca ctgtttcctc aacattctca cggtagtaat agtcaactgt
     4741 tgcaccgtct tctggtacgc atttgcagga gttgctacca aggtgtatgt tgttttcctt
     4801 gtgataactc ggtcttcttt gtcctcagtt gttgttttcc cttcaatagt ttttgattct
     4861 gtggtatact cagaacctat cgctaaatca gcttttataa cagactctgc caacttctct
     4921 tggctacctt ctttatagta attggctgtt actgtagcag tggttggcgc ttcgctttct
     4981 ctataaacta aggtcactgt tctaccttcg cttacaatat tcccagttaa acttgcagaa
     5041 tttgtatctg cttctttaaa agtataatat tttccgtcag tagtagtcat gctactgagt
     5101 tttttatctg tgacattgta gctggtacca atcagttgtt ttttattggt aatgtaggtt
     5161 ccgtcacttt ctttttctcc aattccagta tcatttttca atgatagcaa acgcccttgt
     5221 tcatcaacat agcgaacttt cacattttct gagattagtt ctgccaattc tgaggttttt
     5281 ttctttttct tgatttcttc ggttattttc cctttctctt cttcgggaat atttagtttt
     5341 ggaatgattt tttcaacaac ggttcgtgat ggttccacag tatcttggat gactgaaaag
     5401 tcagctagaa ttgggagatt atactgaaca cggtgacttt gagtgtttac tcctactctt
     5461 tcattattct ctgaaaatac ttgtacggta taagaaacaa catcttttcc taatagaaca
     5521 tccccagtag agaaatagcc gccttttcct agtttgctat ctccagagtc cacttctttc
     5581 ctaatcttat cagatagttt tttaccagtc agtacattcg ttcgcacaat ccctttgtct
     5641 acccctacaa agtgggagaa ctttttgaac tcttcagaac cagatctagc ccaaccatta
     5701 ttaagggcat ttgcttttgt atttgtattc tctctcaaag gtttggcgat tagaattata
     5761 ttcatcggca cttagagttg ctgctatatc tgactcttga ataccaactt ccttactacc
     5821 atttctagcg gcagtatatg tgtatttatc tgtttctact tctagctgat tatccttaac
     5881 atgataggta attttctcct ggtataagag tcttcagtag tttatatgct ctgtcatcat
     5941 ctttagcttt agaagcagct gagtttagcc aagttggggt attaggagta tctttatcag
     6001 cctgtttcaa gacattattc aagtcatttg ctaacctatt ggttgtcctc actgtgaaag
     6061 ttttcttcca gtctgaatca cttttattag acttagatat gctcatgaaa tcctggtcaa
     6121 cattcaacac aatatcgcct tgttttttag catcttccgt tgcttctgct tcaaattgat
     6181 catggagttt ttgttgctct ggtgtatagt ttttttattt acacgattta atgtactatt
     6241 ttttatttta gtattaagaa ctccattaat acgattttta aattctgctt caaaaaatcc
     6301 cttaatttgt tggtgcgcaa gttcaacatt caaacctttc ttatacaagt cttcattctg
     6361 atacaagtct tcattctgaa cgatttcggc tacacggtga atggtttgat cgtataccgt
     6421 cttctcttaa ccagcagtat ccttagtttt aatgactact cgataggttc ctttagaacc
     6481 gttatagtca tctagtttta aaaaagcatt ccaaacattc aaaaatagtt ggaacttccc
     6541 ttaataaatc cgtcactttc tttttcaaga tagcccaagc ttgctcaata ggattcaaat
     6601 ccggtgaata aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag agttcatcca
     6661 aaatgttctt gggatgaaaa ctagcattgc ccatgacaat aacatgaggc gtcttcaaag
     6721 caggtaggag ttgcgttttg aaccactcca caaagaaatc gcttgtcatg cttttcttgt
     6781 aaatcatggg agctataaac tctccgtcta cttgtcctgc aacaattgaa gttcgctcaa
     6841 aacgacgtcc gctaatcttt tcatagactt tctcccctct aggagcccct gcataaggac
     6901 gatagaggta gcggtcgatt cctgtttcat caatatatac gattggtaaa tcttttaggt
     6961 tatccaaaat atcaagaaac tcagcgactt tctctgactc ttgttcctta aagatcgtca
     7021 tcttttttta aagtgacctt aatctgcttt aaagctgccc atactgaagg aacagcacaa
     7081 tcaaaatgtg ccgcaatttc ccgtaaaaaa gcatctggat gagcctctac aaaggctttc
     7141 aattcttcta aagggatctt acgctttttg acgactcgct ttttccgctc taagttcctt
     7201 tgttcacgtc tttcttttcc cacgtgaaga gagttctgac gccaacacca aaaaactttg
     7261 gccgcctcga catgtctgtg ccctcctttg atggaatcta atgctccttg tttaaaatca
     7321 gtattatatg ccatagcttt attagaccat gcttatttta aactaagcaa ctatatcaat
     7381 gttttgttat gagaagactt acttttttta ctgaaattga atttttccta gcctcaacat
     7441 catataaccc caaaattcaa tctgacctgg tttgaagaga tgttcgaagc agataaggtt
     7501 ttactaaaac taaaaaaaat gatataatca aactgattaa atgttttaaa aataaaggag
     7561 aatttgaatg tcttaccaag aaaattacca gaaatgggtt gattttgtgg agcttcctga
     7621 ctaccttcgt caagatttgg aaaatatgga cgaaaaaact aaggaagatg ccttctatac
     7681 aaatcttgaa tttggtactg caggtatgcg tggcttggtt ggtgctggta caaaccgtat
     7741 caacatctac gttgttcgcc aagctactga aggattggct cgtttgattg agtcaaaagg
     7801 tggaaacgag aaagaacgcg gtgtagcaat tgcctacgat agccgtcact tctcacctga
     7861 gtttgccttt gaatctgcgg cagttcttgc taaacacggc atcaaatctt acgtatttga
     7921 aagccttcgt ccgactccag aactatcatt tgcagttcgt catctcaact gtttcgcagg
     7981 tatcatggtc acagccagcc acaaccctgc tccatttaac ggttacaagg tttacggtga
     8041 agacggtgga caaatgcctc cacacgatgc ggacgctttg actacttata tccgtgcaat
     8101 cgaaaaccca tttgcagttg aagttgctga tgtggaaact gaaaaagctt ctggcttgat
     8161 tgaagttatc ggcgaagctg ttgacgtaga ataccttaaa gaggttaagg acgtaaacat
     8221 caacccagcc ttgattgaag aatttggtaa agacatgaag attgtctaca caccacttca
     8281 tggtactggt gaaatgttgg ctcgtcgtgc tcttgcccaa gcaggatttg actctgttca
     8341 agttgttgaa gcgcaagcaa ctgctgaccc agacttctca actgtaacat ctccaaaccc
     8401 agaaagccaa gcagcctttg cccttgctga agaacttggt cgtcaagttg gtgcagatgt
     8461 tcttgtcgca actgacccag acgctgaccg tgttggtgtt gaagttcttc aaaaagatgg
     8521 tagctacctc aacctttcag gtaaccaaat cggtgctatc atggctaaat acatcttgga
     8581 agctcacaaa aacgctggaa ctcttcctga aaatgccgct ctctgcaaat ctatcgtttc
     8641 aactgacttg gtaacgaaga ttgctgaaag ctacggcgca actatgttca acgtcttgac
     8701 aggtttcaaa tttatcgctg aaaaaatcca agaattcgaa gaaaaacaca accacactta
     8761 catgatggga tttgaagaaa gcttcggtta cttgattaaa ccatttgtac gtgataaaga
     8821 tgccatccaa gccgttcttg tcgttgctga acttgctgcc tactaccgtt ctcgtggttt
     8881 gacacttgct gacggtatcg aagaaatcta taaagaatat ggctactacg cagaaaaaac
     8941 aatctctgtt actctttcag gtgtcgatgg tgctgaacaa atcaaagcga ttatggctaa
     9001 attccgcaac aatgctccaa aagaatggaa cgcaacagct atcactgtcg tagaagactt
     9061 caaggcacaa actgctactg ttgctgacgg tactgttaca aacttgacaa ctcctccaag
     9121 tgatgtgttg aaatacacac ttgttgacgg ttcatggatt gccgttcgcc cttcaggtac
     9181 agaaccaaaa atcaagttct acattgcagt tgtaggggaa accaacgaag aatcacaagc
     9241 taagattgct aacatcgaag cagaaatcaa tgcatttgta aaataaagac ctataaaaga
     9301 tgagaccaac caacctcatc ttttttcgta tcaaatctaa gcaattttag aaactttatg
     9361 gcatactaga cttatcaatg aaagcgaggt aatctcatgg aacaattttt agataacatc
     9421 aaagaccttg aagtcactac agttgtgcgt gcgcaagaag ctcttgataa aaaagaaact
     9481 gcaaccttct ttatcggtcg caaaacttgc ccttactgcc gtaaatttgc aggtacattg
     9541 tcaggtgtcg tagctgaaac caaagctcac atttacttca tcaatagtga agaaccaagc
     9601 caactcaatg atttgcaagc attccgctca cgctatggaa tcccaactgt accaggtttt
     9661 gttcatatta cagatggaca aatcaacgtc cgttgcgact cttcaatgtc agcacaagaa
     9721 atcaaagatt tcgcaggatt gtaaaaaatc agctaacaag tcttaaaatc acaaaaacgc
     9781 ataatgtaag gtgcaaaaac cttgatatta tgcgttttat tgttcctaaa acagttacat
     9841 cagcatttca ttacagaaca ttttaatttt ggaagtcaaa tcaattttta acaatgtttt
     9901 agaaatcaca gtgggctatt ccatattaaa ttatccagat tcaatcgcta ttatcgtttt
     9961 cctagattac aaaaaaactg cgttttgcta atcaaaacgc agtctcagcc actattttat
    10021 cttactgtcc ttcttttact tctttggttg ctacatcttc tccaaaccat ttttggctga
    10081 tttcttggaa cttgccgtcc ttgtaaagac tagaaaaagc ttcatttatc ttcttaacca
    10141 aggttgtatc ttccttacgg gctccaaccg caaaagcttc tgtttctagt ccaactgtaa
    10201 agacattata atcgtttaaa acaccttctg cttctaaata atagtttgca tagacacggt
    10261 caatcaatag accatcaatt cgatcgtttt tcaaatcaat caaggcttca ttaaaggttt
    10321 ggtattgatt cgcttcctta ttagcgacaa tattcttcaa aatttctgga tttgcttcaa
    10381 agtccgcata accagatgaa ccagcttgag ctcctaatgt ctttccagtc atatcctttg
    10441 cagtcgtgat accagatgat ttcttcgtaa ccaatacctg ctcattcttc atatatgagt
    10501 tactgaaagc caccttttca cggcgttcgt ctgtagcgga atagccattc caaatcagat
    10561 caatcgttcc ttttgtcaat tcagcttctt tcaaatccca atcaatcggt tgccaattta
    10621 ccgtgattcc gtatttttca aaaacagctg tagctaaatc aatatcaaat cctgcataag
    10681 aaccatcttt ctgagcaaat cccattggaa caaaagtact atcaaatcca atagtaatag
    10741 acttgttaga ctggtacttt gaccaattat ctccactagt ttcgctagaa tttttcccac
    10801 aagctactaa gaacaaagca gtcatcagac tgactaatac aagcatccat tttttcatcc
    10861 atttttcctc ctatttaggt tctactttca ataatacatc tgcgatattt tcagcaaact
    10921 gcaaatcatg ggtaaccaca atctgggtca tcccaagttc cctattttgc aagattagct
    10981 tctccacttc caaacgtaat tctggatcca gggcagaagt tggttcatcg tagccaatga
    11041 tttctgggtc aatcatcata gcacgcgcca aagccacccg ctgcttttgc ccaccagata
    11101 gtgagaaagg ataggcctct gcgtgtcctc ctagtcctaa ctgttccaag agtccactcg
    11161 ccttcttctc agcctcttcc tgcttcattc ccatggtctt cacaggcgat aaggtcaaat
    11221 tgtccagaac tgataaatga gggaacagtt gaaaatcttg gaatacaaat cccagtagat
    11281 tgcgcttctg caattcatcc agctctaaag gttgtccatt ataaaagatt tgccctgaat
    11341 caatggtttc aagacctgca agcatacgta aaagagttgt cttacctcca ccagaaggtc
    11401 caacgatagc caggatttgc ttttcaggaa tacttagact gaaattagac aggatttgtt
    11461 tgtctccaaa gactttattg atatttcgta attctaacat ggcagcctcc tatctataat
    11521 aactatactt cttctcaact tttttggaaa taattgtcac aatcccaatc aaaatcaaat
    11581 aaatggctcc tgccaagaac ataggaacta gactagcatc gcggttagca gctgttcgac
    11641 tagccaagat aaggtctgaa attccgagag catagaccaa agaagtatcc ttgaccaaac
    11701 tcataacttc attaaagaca ctaggaagaa cgatcttggt cacttggggc aagataatat
    11761 agcgcactct gtcaaaaggg ctaaacttca agaccttggc ggcctcatac tgtcctcttg
    11821 gaatagtgtc aattccccca cggaaaattt ctgcaaagta agctgcatag ttgagaacaa
    11881 aggcaataat agctgcagga aggcggtcta aacgaatccc aatacttggg agcacataat
    11941 agataaaaat cagttgcaag agtaaggggg ttcctcgcat aacccagatg taaatgttaa
    12001 tcagataatg gaggggcttc caatggactt gcaaggcaaa ggcaatcaaa acgcccaagg
    12061 gaatcgaaaa tagcaagacc agtgcaaaga cctgtacagt cgtgctcgca ccattcagta
    12121 aactcggtaa tatctcaaat aaataagaca tactgcacct cctaaaagta attgttccta
    12181 ttatagcatg aataaacaag attaccaagt atttttgtaa aaagattcta ccatatacaa
    12241 ataaaaaccg tagctatcaa aagagataaa ctacagttct atatgtttaa acattcttac
    12301 aatctctcaa acagttcttg catttgcaca tcatctggaa ccagttttaa gtaagtgtga
    12361 gcatggactt ttgcttcttc aaaatgtccc aattcacgca agagatagat atagtgttcc
    12421 agaaattctg gattgtcctt caaatctcct atcaactctt gataatgctc ataagcagta
    12481 tccaaatcgt ccatttcttg ataagaacga gcaatcatcc acttggtcaa aagattttct
    12541 gactcctcac tctgcaagtc tagaatatcc tcataacgct cctgctccag ataaatagtg
    12601 gctaaacgaa gcaagatttc ttctgtatcc tcagcgtctt cttttgcagt aaggagataa
    12661 ttttctgcac cactagcatc atgcaattca taagaaaatt gtgaagcagc tagcaagagg
    12721 cgagtttcaa agggattttt ctctaatcct tgcttagcga tacgcagggc ttcttgaact
    12781 tgatgttcct tatgtaaagc ctgactgtac ccatactcat agccttcaaa gtcaggagaa
    12841 atggtatcaa gctgcttaaa gtagagggtg gctttttgat attcttcttg atcaaaataa
    12901 agactggcca actcaaaagc tgttaagtca tcgtattcta actccagggc tttttctaaa
    12961 aactcagtag ccgtttcaaa tttccctaac tgagcatagg caaagccaat tcgttgatag
    13021 gtggaaatgc ccgtttgctc ataaatcgag cgattatcta actgggcata ggcttgaata
    13081 gccgcttggt aattttccaa ctcactatcc aactctgcca aacccaatat caagagagaa
    13141 tcctctgagt aggtcaaggc ctccaataat ttctcacgtg ccacatctgt caaaccttcc
    13201 agctggtaaa ggtctgcctt cagagccaaa gacgagacat accagtcact gtcagcttgg
    13261 atttcctcaa gataggtaaa ggcttcttct atttgaccat cctcgctagc aattgcagct
    13321 agattaagat gaacctctgg aaaatcctct acaattttca ggtaaatttc cttggcctga
    13381 ggatagaaac caatcccttc aagataagtt gccaactcat acagaagatc acttgaatca
    13441 ttttctaaag ctttggcgaa ataatgctca gccttagtta aatcttgctc ctccaaagcc
    13501 tgtaacatct gttgactatt gttcactctt gacttcctca ccctctaatt catatagacc
    13561 actgactacc ttataccatt cgaaaatggc tgaaatgaca accttagcag aggcataaac
    13621 cggaatacca agtaaaactc cccagatacc aaacatagat cctgaagtta acaaaacaaa
    13681 gagaacatta atagggtgga tgtttaattg acttcccaaa atcaatggag agacaaaacg
    13741 gccttcaata gtttgttcta cgataaagac aatcactact ttcaaaagca tgactggacc
    13801 agcaatcaaa cccaatacta gagcaggaag catggctaga aagctaccaa gataagggac
    13861 cagatttaaa ataccagcag taacccccag cgtaaccgca tagcgtagac caataatctt
    13921 gaagaagatg ataaacatta ctgctacaat aatagccact gtcacttgcc ctcgaacata
    13981 gttggacaac tgttgattca catctgataa aacttgtcca acaggttcct tcaattttct
    14041 tggaatgaat tgggtcaaat agttacgcaa gcctttccca tcacgcaaga gataaaagag
    14101 catgaaagga acgataatca aggcaacaat cacttgagaa gctccgctaa taaaggcact
    14161 cacccagttg actgcctgag atgaaacctt acttgccaaa actgtagcct ggctagaaaa
    14221 attggtcaaa acttgctcta attgaggtct gaaatcatct ggcaggtgct gggctaccaa
    14281 tccattaaca atcctatcta tatcttctaa gtaaacagga acgtttcttg caaaggtcaa
    14341 aacctgacgt tgcagatttg gaatggcgac tgccaagccc caaatgataa agagagcgat
    14401 gataacaaag acaatagtga tagctataac acgattaacc ttatgcttct ccatccaatc
    14461 aacaatagga ttcaacaaat aatataacaa accagacaaa atgactggca acatcacaac
    14521 tgctaaaaag tctaaaacag gtgaaaatag aaaactaatc ttacttaaaa taaaaagatt
    14581 cagtcccaat aataaggtta ctaaaaatac cgtaattgcc ttgttatcta aaaaccactt
    14641 gaaaaaccaa gataggctaa aatgtttctc tttttgctcc ataaatactt cctttctatt
    14701 gttctctcat tataccattt ttgaaacaaa ataactcttt tttaaagtgc ttacatctaa
    14761 ttggatatct ttaatttact tgtttttgtg atataatagt cttatcttta cacagaggta
    14821 tagtaatgaa agaaactgtt tattttggaa cttatacacg tcgtacttct caagggattt
    14881 acaaggcaga ctttgataca gaaactggtc agctttcaaa tctagaactt tttgcagctg
    14941 agccaagtcc aacctacctt gcctttgacc agcaccaaca tttatacact gttggtagcc
    15001 aagacgataa ggggggaatt gcagcctatc aaactgacgg gactgtgtta aatcatgttg
    15061 ttgaagaagg agctccccac tgttatgttg ctgtcgatga aaagcgtgat ttggtttacg
    15121 cagccaacta tcacaaggga caagtccttg tttataaacg ccaggaagat ggtagtcttc
    15181 tacttagtga tatggatcaa cacagtggcc aaggtccaca tgaaaatcaa gcttcccccc
    15241 atgttcacta tacagattta acacctgacc actatctagt gacctgcgac ttgggaactg
    15301 accaagtcat cacctatgac ctcgatcaag aaggaaaatt atctaagctc tatacctatc
    15361 acagcaagcc aggagcaggc tcacgccata tcattttcca taaccactat aaaatcgctt
    15421 atctcatttg tgaactcaat agtactatcg aagttttaat ctacgatggc gttggcgaat
    15481 ttgaacgtat gcaggtcatt tcaactttac cggaagctta cgaaggcttt aatggaaccg
    15541 ctgctattca tctctctaaa gacggtaaat acctctacgc ttctaaccgt ggccatgatt
    15601 ctatcgcagt atataccatc cttgcggacg gtagcttaga gttattagaa atcgttccaa
    15661 cgcatggtca gactccacgt gattttgatt tgacacccga ccaaaaattt ctcattgttg
    15721 tccatcaaga ctctgacaat gcaactgtct ttaaacgtaa ttgtgacaat ggtcgtctag
    15781 cagaactctc caacgacttc catgttcccg aagcagtctg catccgtttt gctccttaaa
    15841 acaccataaa aaatgaactt ggtattttca agttcatttt ttcttatagt ctatttccga
    15901 cattaatacg gttaatagca cgttgcaaag caatcttagc acgacgttct tggtcaatca
    15961 aatgtttgtc ttgtgcttct tcaattgcac gttctgcacg aagtttggca cgttctgcac
    16021 gactgatatc gatatcacga gcacgttctg cagagtcagc gacgattgtg atcatatcat
    16081 tggcaatttc aataacacca ccgtttactg caatccagtt cacgtgatct ttatcatcga
    16141 tacgttttac ctttacttca tcaactgcta aaaccgcaat catattttca tgtcgtggca
    16201 agatccccat ctcaccatcc agagttcgaa ccgatacata gctggcatgg tgatcataga
    16261 cgagaccatc tggtgtcacg atctggacag ttaactgagc catagttcac ctcttaaaat
    16321 cccatttttt cagcttttgc aatcacatct tcgatagaac ctacaccacg gaaggcatct
    16381 tctggcaagt ggtcgtattt accatcaagg atttccttaa agccacgtac agtttcagca
    16441 actggaacat aagaacctgg ctgaccagta aattgttccg caacattgaa gttttgtgac
    16501 aagaagaact ggatacgacg ggcgcgagca accaaggtct tttcttcatc agaaagttca
    16561 tccataccaa ggatagcaat gatatcttgc aattcatggt aacgttgaag gacacgtttt
    16621 acttcagcag caactgcata gtgctcttct ccaacgattt caggtgccaa ggcacgtgag
    16681 cttgaagcaa gtgggtcaac ggctgggtag atacccaatt gtaccaactt acgttccaag
    16741 tttgttgttg aatccaagtg agcgaaggct gttgctggcg ctgggtcagt atagtcatcc
    16801 gctggcacat agatagcctg gatagaggtt acagaaccct tcttggttga tgtgatacgt
    16861 tcttgcaatt gacccatttc cgtagcaagt gttggttggt aaccaacggc tgatggcata
    16921 cgacccaaaa gggcagatac ttctgaacca gcctgagtga aacggaagat attatcgata
    16981 aagagaagca cgtcttggcc ttccacatca cggaagtatt cagcgattgt caaaccagta
    17041 agggcaacac gcatacgtgc tcctggtggc tcattcatct gaccaaagac catggctgtt
    17101 ttctcgataa cgcctgattc tttcatttcc cagtaaaggt cattcccctc acgagtacgt
    17161 tccccaacac cagcaaatac tgaaatacca ccgtgctctt gggcaatgtt gtgaatcaat
    17221 tcttggatta agacagtttt accaactccg gcaccaccga aaagtccaac tttaccacct
    17281 ttaaggtaag gggcaagaag gtcaataacc ttgatccctg tttcaaggat ttcagaagag
    17341 gtagacaact catcaaaagt tggagctttt ttatgaattg gctgacgctc tgcgtcttct
    17401 gtaaaaggag cttccaagtc aatggtatct cccaaaacgt tgaagacacg tcccaaagtt
    17461 tctttaccta ctggtacaga gattggacga cctgtgtcca atacttccat tccacgagtc
    17521 aacccatctg ttgattccat ggcgatagta cgaaccatac catctcctaa ctccaaggct
    17581 acttcaagga cgatttttgt ttttctttcg tcatttttgt agacgacaag tgcattgtta
    17641 atctcaggaa gtttttcccc tgctgcaaac aaaacgtcta caacgggacc gataacctga
    17701 gcaattttac ctgaactcat ctccttctcc tattctatat aagatactgt cggttcctag
    17761 ctcaactagg tcctaagttc attttcatac gagctggact agagcctatt ctaaggcact
    17821 agcacctgct acgatttctg taatttcttg tgtaatcgcc gcctgtctgg cacggttata
    17881 ctgaattgtc aaatcattga tgactttctt agcattatct gtcgctgttt gcatggctgt
    17941 catacccgca gcattctcag ctgtcttggc atctataatg gcaccgtaaa tcatactttc
    18001 tgcaaactga ggcaacaact gctccagaat ttcttctcgg ctggtttcca attcaaaagt
    18061 caagctgtac tcttcatccg cttcatttgg atccaagtca acaatcggaa gcatttgttc
    18121 cacacgcatt tgactggtta gcgtattgac atggtggttg tagcaaacat aaagctcatc
    18181 aaagagttca ttttggtaca tttcaacagt ttttgaaata atcttacgaa cttgatcaaa
    18241 gctaggttgg tctgccaagc cacgtaattc ataaagtggt tgaataccgc gagccttaaa
    18301 gaaatcagct cccatcccac cgatacagat catttcaaaa cctttaccgt ctgggtggta
    18361 ttcttctttc aactccataa cagctttcaa aatagaggaa ttataacctc caaccaaacc
    18421 gcggtctgaa gtgataacga tatagcctgt cttcttcaca gaacggctaa tcaacatcgg
    18481 attagttgaa gcaccagctc cattaccatg aaggatatct gtcaaaagtt tacgcacttt
    18541 ctgagcgtaa acttggaagt tgcgagcagc ttcttcagag cgacctagct tagcagccga
    18601 taccatttgc atggcattag tgatttgact cgtatttttt gttgaggcga tttttgtttt
    18661 aatatcattt agagatactg ccatctgaca cctctattct tattggaagc tagattgatt
    18721 gagaaactct gtaatcgcag catccaagac tgcttcttct ggcaagtctt ttgtatcacg
    18781 aatggtttcc aaaatctctg gatgttgagc atcaaagaag gcatggaact cttcctcgaa
    18841 acgaacaata tcatctactg gaacagtatc caagaaacca tgtgtcaaag cataaagaat
    18901 ggttacttgt ttctcaacag gtaatggttt gtgaacaggt tgtttcaaga cctcaacggt
    18961 acgacgtcca cggttcaact tagcctgtgt tgctgcgtcc aagtcagaac caaacttagt
    19021 aaaggcttcc aactcacggt atgaagcaag gtcgatacga agtgtaccag caaccttctt
    19081 catggctttg atttgtgcag aaccacctac acgagataca gatgaacccg catcgatggc
    19141 tggacgaata cctgcattga agaggccatc gccaaggaag atttgtccat cagtgataga
    19201 aatcacgttg gttgcgatat aggctgagat atctcctgct tgtgtctcga taaatggtag
    19261 ggctgtaatt gatccaccac caagttcatc agaaacttta gctgagcgct caagcaaacg
    19321 gctgtggaga tagaaaacat cccctgggaa ggcttcacga cctggaggac gacgaagcaa
    19381 gagcgacagt tcacgataag ctaccgcttg ttttgataga tcatcgtata caatcaaaac
    19441 atgcttacct tgatacataa attcttccgc catagcgacc ccagtataag gagctaggaa
    19501 gagcaatgga gatggttgtg aagcagaggc tgtcacaacg attgtgtagt ccaaggcacc
    19561 gtactgacga agtgtttcta cttgcgtacg aactgttgat tctttttgtc caatcgcgac
    19621 gtagatacag atcatatctt gatctttttg gttcaagatt gtatcaatcg caatggttgt
    19681 tttccctgtc tgacggtcac cgataatcaa ctcacgttga ccacgaccaa tcggtacaag
    19741 ggcgtcaata gctttcaaac cagtttgcaa tggttctgaa acagacttac gttgcataac
    19801 accaggagct ggtgcttcta ctggacgagt tttatcagtg tggatttctc caagaccgtc
    19861 aactggacga ccaagcggat ccacaacacg accaatcaga ctttcaccta cagggacttc
    19921 catgattttc cctgtacggc ggattgtatc gccttcacgg atatctgtaa agtcacctag
    19981 gatgataata ccaacgtctg ttgactccaa gttttgagcc ataccataag agccgttttc
    20041 aaaattcaac aactctccac tcatgacatt ttcaaggccg tgagcacgcg cgataccgtc
    20101 cccgatatag gttacaacac ctgtttcagt cacatcaaaa ttgggtttga aattttcaat
    20161 ttgttgctta attaaagcgc tgatttcttg tgcgttaatt gccaaaagaa caccactttc
    20221 tatttcaaat tttctttaac aactttaagt tgttgtttaa tactcacatc aattgtcttg
    20281 tgattggcaa aaatgacaaa accaccaatg agactttcat cgatttgttc ttttacactc
    20341 cttactttca gagacatttt tttctcaatc aaagggagca aacgagtctt ctgttcatca
    20401 gttagaggat gagcagacgt aatcgtcact tcaaatcgat ttgtttcttt ttcaagtcgg
    20461 ttcaagcaat ctacaagcac atcataaaaa agatttgctc tgtgattgta ggccagaacc
    20521 tggataaagt tttgtaataa aggcgacaca gaatcttgga aaaaagcaat tgttttttcc
    20581 ttatccgact cgtctactgc cacttgtttt aaaaaagaag gcagacctgt tttttcaaca
    20641 acttgcttga tttgagtcaa gtctgaaaag atacggtctt cttctccttt ttcaagtacc
    20701 aattggacaa aaggcatgct gtatttttca attaccttta ctgttttctt gtccattaag
    20761 cttctcctag ctgatcgata tactgatcaa tgagtgcttt atgggcatga ctgtcaaggt
    20821 tttgtgagat gattttacca gctaagctga tggtcagatc tgcgacctca cccttaacac
    20881 tctgtaaagc ttctacttta ttttgagcaa tttcttgatt ggctttttct tttaagtgtc
    20941 ctgcttctag tttagcatct gctaagatat tagccttact ttgctcagct gtttcctttg
    21001 cattttcaat gattgtctta gcttctttac ggctaccagc caattcatct tcgcgttttt
    21061 gagccaatac ttctgctttt tgacgggctt cttcagctct gtcaatatct gaagcaattt
    21121 tttcagctct ttcttcgaaa atgcctgtaa tattagacca tgcaaatttt ttaatcaaga
    21181 ctagcaaaag aataaaagag ccagtgatta aaataaaatt accaattaat tcacctactg
    21241 ttacgtgcat cagttactcc tttctattcc tcttcaatat taatcttatt ccctaaatac
    21301 acagatgtca aaagagtaaa aacataagct tggatgcagg aaataaagac agaaaatgca
    21361 gtccaagcca aattagctcc aaaggctact ggataccaat aaatagcttg gtgggaaaga
    21421 agaagtaaca aactcgtcat gacctctcct gcaaagatat tcccaaaaat ccgcaaagcc
    21481 aaagataaga agtttgtaaa ttcttccaag atattcatcg gtatgacaaa aacaggactc
    21541 ataaaagatt ttatactttt tttaaatcca cgacgacgaa cgctttctat atgtgtcaac
    21601 aaaatgacaa gaaaagataa ggttaagtca tactgtaaat tagcggttgg cgaactccac
    21661 cagttagtcc catcgatcgt ttgaagcttt gtcattaagc caaggttatt ggcaatcacc
    21721 atgaaaagga ataaacaaag gaaaaagagt gaataatctt tcatgtagcg cgaaccaatg
    21781 ttaggttctg taaatccaat aacaaagtca tagacatact caagtacatt ttgctttcct
    21841 ttgggtttca aggtcatatt gcggcttgcc caataaataa agacaaaaat aactcccaca
    21901 atcaacaaag tcatggctaa catagtcaga ttgaagataa caggaccaat agagatgatt
    21961 ggattaatac tttcttccat ctaaaatcct cccttttctt ctcgttccat gtatttattt
    22021 gataataaat gagaagacaa gagttacaaa gaaagttcct tcaataaagg caacacctaa
    22081 aaacatcaaa ctacgaaact cagaaagcat atctggttgg cgtgctactg atttaaacag
    22141 tccattcatc aataaacctt caccgacaga tacgcccata caggcaatac ataagcctaa
    22201 aaatgttaaa ttcataacaa attctccttt aaaataaaat ttacttactt agtgtagtcc
    22261 taaaatttaa atttgtcaac ttttaaccgc tattggaagc gtttaataaa aattatttcc
    22321 attttgctaa atttcaagtt caagttagcc atccaaaagt cttctctggg tgacttgtag
    22381 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
    22441 gtcattttct tggttccctt aggtaaccat ctacgaatga gcctgttgtg attctcatta
    22501 gttccccttt cccaagaggc atagggatgt gcataataaa tgtgctcctc agaaaataca
    22561 ttagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
    22621 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
    22681 atgatctgat gtctactttt tcgatccgtc aagacaagca agcagtagtt tttcgctctc
    22741 gtaagtagaa ctgtatcaat ctcataatgc ccattctcca agcgaaaatt gatagcttca
    22801 agccgctgtt cgat
//
LOCUS       DAVMCG010000027        22672 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVMCG010000027 DAVMCG010000000
VERSION     DAVMCG010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.028"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            429..725
                     /locus_tag="VYP66_001346"
     CDS             429..725
                     /locus_tag="VYP66_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1850893.1"
                     /translation="MDTPDENGYVADNYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGKGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            846..1790
                     /gene="manA"
                     /locus_tag="VYP66_001347"
     CDS             846..1790
                     /gene="manA"
                     /locus_tag="VYP66_001347"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1850894.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGIFILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1811..3289)
                     /locus_tag="VYP66_001348"
     CDS             complement(1811..3289)
                     /locus_tag="VYP66_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HEV1850895.1"
                     /translation="MVFLTDLRKHDRIVKSINQTEGYLTTQVAFSYFEKGDQSLTMSE
                     KSQWGSKLGFILASAGSAIGLGSVWKFPYMTAANGGGGFLLIFLISTILIGFPLLLAE
                     FALGRSAGVSAIKTFGKLGKNNKYNFIGWIGAFALFILLSFYSVIGGWILVYLGIEFG
                     KLFQLGGTGDYAQLFTSIISNPAIALVAQAAFILLNIFIISRGVQKGIERASKVMMPL
                     LFIIFVFIIGRSLSLPNAMEGVLYFLKPDFSKLTSAGLLYALGQSFFALSLGVTVMLT
                     YASYLDKKTNLVQSGISIVAMNISISIMAGLAIFQARSPFNIQSEGGPSLLFIVLPQL
                     FDKMPFGTIFYVLFLFATVTSSVVMLEINVGNITNQDNSKRAKWSVILGILTFVFGIP
                     SALSYGVMADVHIFGKTFFDAMDFLVSNLLMPFGALYLSLFTGYIFKKALAMEELHLD
                     ERAWKQGLFQVWLFLLRFFVPSFQSSSLWSSLPNLCNQKGLE"
     gene            3372..4126
                     /locus_tag="VYP66_001349"
                     /pseudo
     CDS             3372..4126
                     /locus_tag="VYP66_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(4146..4601)
                     /locus_tag="VYP66_001350"
     CDS             complement(4146..4601)
                     /locus_tag="VYP66_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1850896.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4621..5796)
                     /locus_tag="VYP66_001351"
     CDS             complement(4621..5796)
                     /locus_tag="VYP66_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1850897.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEKNREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5855..6700)
                     /locus_tag="VYP66_001352"
     CDS             complement(5855..6700)
                     /locus_tag="VYP66_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1850898.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAENIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6825..7382
                     /locus_tag="VYP66_001353"
     CDS             6825..7382
                     /locus_tag="VYP66_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1850899.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7401..7868
                     /locus_tag="VYP66_001354"
     CDS             7401..7868
                     /locus_tag="VYP66_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1850900.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7957..8586
                     /gene="upp"
                     /locus_tag="VYP66_001355"
     CDS             7957..8586
                     /gene="upp"
                     /locus_tag="VYP66_001355"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1850901.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8760..9350
                     /gene="clpP"
                     /locus_tag="VYP66_001356"
     CDS             8760..9350
                     /gene="clpP"
                     /locus_tag="VYP66_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1850902.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9429..9677
                     /locus_tag="VYP66_001357"
     CDS             9429..9677
                     /locus_tag="VYP66_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1850903.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9778..10938
                     /locus_tag="VYP66_001358"
     CDS             9778..10938
                     /locus_tag="VYP66_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1850904.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            11206..12075
                     /locus_tag="VYP66_001359"
     CDS             11206..12075
                     /locus_tag="VYP66_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1850905.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLVTAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            12079..13035
                     /locus_tag="VYP66_001360"
     CDS             12079..13035
                     /locus_tag="VYP66_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1850906.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAVVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            13035..13799
                     /locus_tag="VYP66_001361"
     CDS             13035..13799
                     /locus_tag="VYP66_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850907.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPVFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13799..14509
                     /locus_tag="VYP66_001362"
     CDS             13799..14509
                     /locus_tag="VYP66_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850908.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14817..15473
                     /locus_tag="VYP66_001363"
     CDS             14817..15473
                     /locus_tag="VYP66_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1850909.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15581..16676
                     /gene="prfB"
                     /locus_tag="VYP66_001364"
     CDS             join(15581..15652,15654..16676)
                     /gene="prfB"
                     /locus_tag="VYP66_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1850910.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16694..17386
                     /gene="ftsE"
                     /locus_tag="VYP66_001365"
     CDS             16694..17386
                     /gene="ftsE"
                     /locus_tag="VYP66_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1850911.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKKRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17379..18305
                     /locus_tag="VYP66_001366"
     CDS             17379..18305
                     /locus_tag="VYP66_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850912.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANAPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18591..20771
                     /locus_tag="VYP66_001367"
     CDS             18591..20771
                     /locus_tag="VYP66_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1850913.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20823..21638
                     /locus_tag="VYP66_001368"
     CDS             20823..21638
                     /locus_tag="VYP66_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1850914.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            21844..>22672
                     /locus_tag="VYP66_001369"
     CDS             21844..>22672
                     /locus_tag="VYP66_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1850915.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVTSGVDLPKFIQKKA
                     PKDGSTYFNRTRVFAEEPTTKTYIDSVNDGTWTFKGYDAASAVVNKANVEFVGKWEFK
                     "
BASE COUNT         6954 a         4230 c         4927 g         6561 t
ORIGIN      
        1 ttgtttgatt acagtctata gtgtattgaa tctataacag tacaccttgg ctgctaaaat
       61 atttctataa attaatttga ctttcctgat agagttgttc acatcttatt tcaaactact
      121 ataaaagttc tataatctct ttataagatt tgcccatcag acgaaatata atggattgaa
      181 actagaatag tacacctctg cttctaaaac attgttagaa atcaatttga ctgtcctgat
      241 caatttgtcc tgttcttgtt tcgttttact atagaacgat ttgaaggcgt ttatgatatt
      301 tagctgtacg agagtctttt aaaagtgttt tgatggtttg gatttcttct ttagttgatt
      361 tcatatcact attatataat gctttttgat tttagtttag tattatcgta gaaaatggac
      421 tcggtgctat ggatacaccg gatgagaatg gttatgtagc agataactat cggattactt
      481 acttagaggc ccacatcaag gccatgcgag atgccattta ccaagacggg gttgacttgc
      541 ttggttatac gacttggggc tgtatcgatc cggtttcagc tggcaaaggg gaaatgaata
      601 agcgctatgg ctttatctat gtagatcgag ataatgtagg aaacggagct ctcaaacgta
      661 gcaagaagaa gtccttctat tggtacaagg atgtcattga tagcaatggt gcaagcatcg
      721 ggtagagcac atttgtttac tatttttata aaatcttctc cctgctttat aagatgtaaa
      781 aaagagttca attcgaactc tttttttgct ataatgaggg gagaaaaatc agacaggaga
      841 tcgacatgtc agaaccatta tttttacaat cagttatgca agaaaaaatc tggggtggag
      901 ccaagctacg tgatgagttt ggctacgaca tcccaagtga aaaaatcgga gaatattggg
      961 ccatctcagc ccatccaaat ggagtctcta aagttgccaa tggtcgttac gagggaacag
     1021 atcttgctac tttgtatgcg gaacaccgtg aactatttgg caatcgtcca gaacctgtat
     1081 ttccactttt gaccaagatc ctcgatgcca acgactggct cagtgtccaa gttcacccag
     1141 acgatgctta tggactcgag catgaaggcg aactcggaaa aacagaatgc tggtacatta
     1201 tcgcagcgga tgaaggttca gagattatct acggtcacaa tgccaagtca aaagaagaac
     1261 tccgccagca aatcgaggac aagaactggg atgacttgtt gaccaaagtc cctgttaagg
     1321 ctggagattt cttctatgta ccaagcggga ctatgcacgc tatcggggcg ggtatcttca
     1381 tccttgaaac ccagcagtct agcgatacca cctatcgcgt ctatgacttt gaccgcaagg
     1441 atgacaaagg caacttgcgt gaacttcatc ttgaaaaatc catcgatgtc ttgaacattg
     1501 gtgagccagc aaatagccgt cctgtaactg ttaaagcaga tgatttgcgt tccactctcc
     1561 ttgtatctaa tgatttcttc gcagtttaca agtgggaaat tactggaaaa gttgactttg
     1621 aaaagacagc tgactacagc ttattgagtg tcttagctgg tcaaggtcag ctaactgttg
     1681 acgggaaaaa ttatccaatt caaaaaggca gccactttat cctaccaagt gatgttgaag
     1741 cttggactct ggaagggcaa ggtttggaat tgattgttag ccatccataa aaagaaaggg
     1801 cctgagttca ctactcaagt cctttttgat tacataaatt gggcaatgaa gaccacaatg
     1861 atgatgattg gaatgacgga acgaagaaac gaagaaggaa gagccagact tggaacagtc
     1921 cttgtttcca tgctctttca tcgagatgga gttcctccat tgcaagagcc tttttaaaga
     1981 tatagcctgt aaaaagtgaa aggtagagag ctccaaatgg catgaggaga ttggaaacca
     2041 agaagtccat agcgtcaaag aaggtcttac caaaaatgtg aacatccgcc atgacaccgt
     2101 aagatagggc tgaaggaatg ccaaagacaa aggtcaaaat tcctaaaata acactccatt
     2161 tggcacgttt gctgttatcc tggttggtga tattgcccac attgatctcc agcatcacga
     2221 cagaagaagt gacagtcgca aagaggaaga ggacgtagaa aatggttcca aaaggcatct
     2281 tgtcaaagag ttgaggcaag acgataaaga gcaggctggg tcccccttca gactggatat
     2341 tgaaggggga tcgagcttgg aaaatggcta gacctgccat gatggatatc gagatattca
     2401 tggctacgat ggagattcct gactggacta gattggtttt cttgtccaag taagaagcat
     2461 aggtcaacat gactgtaacc cctagtgaga gggcaaagaa agattgtccc agagcataga
     2521 ggagaccagc gctagtcagt tttgaaaagt ctggtttgag gaagtaaaga accccttcca
     2581 tggcatttgg caaactgaga gagcgaccga tgataaaaac aaagatgata aagagcaggg
     2641 gcatcatgac tttcgaagct ctttcaatcc ctttttgaac cccacgtgat ataataaaga
     2701 tatttaataa gataaaggct gcttgagcta ctagggcaat ggctggattt gaaatgattg
     2761 aagtaaataa ctgagcataa tcacccgttc caccaagttg gaacaatttc ccaaactcaa
     2821 tacctagata gactagaatc catcctccga taacactgta aaaagataag aggataaaga
     2881 gggcaaaggc gccaatccaa ccgataaagt tgtacttgtt attcttgccc agttttccaa
     2941 aggttttgat agcggaaacg ccagcactac ggccaagggc aaactcagcc agcaggagag
     3001 ggaaaccgat taaaatagtg gaaatgagaa agattagtaa aaagcctcca ccgccattag
     3061 cagcagtcat gtagggaaac ttccaaacgg aaccaagccc gatggccgag ccagcagatg
     3121 ctagaataaa accaagtttc gacccccatt gtgatttttc tgacatagtt aaactctgat
     3181 ctcctttttc aaaataagaa aaagctactt gagttgtcaa atagccttct gtttgattga
     3241 tagacttgac tatcctatca tgttttctaa ggtctgtcaa gaaaaccatt ttcaagtttt
     3301 cacacctttc tcaaaaacgc ttgactctga cctaagggga ggggttatac tatcattgta
     3361 aggaggaaat catgtaccat ataaaagaag ctgcgcagct ttcaggtgtc tctgtcaaga
     3421 ccctgccctg catcactatg acaagatagg actcttggtc cccttaaagt cggaaaacgg
     3481 ctatcgaacc tatagtcaag aggatttgga acgccttcag gtcattcttt actacaaata
     3541 tctaggcttt tctttagaga aaatagcaga gctgttaaag gaagaaagga cagatttatt
     3601 gccccattta actaggcagt tggactatct aactcgcgaa aggcaacatc tggatacctt
     3661 gatttccacc ttgcaaaaaa ctattcaaga acaaaaagga gaaagaaaaa tgaccattga
     3721 ggaaaaattc acgggattta gctatcaaga caatcaaaaa taccaccaag aagcggtaga
     3781 gaaatatggt caagaagtca tgggacaagc gctcgaacgc caaaaaggtc acgaagacga
     3841 ggctacggcc gcctttaacc aagtctttca aactttggca caaaatcttc aagttggttt
     3901 acctgcaaca gcaaccgaaa accaagagca agcagccaag ctcttgcaag ccattcgcac
     3961 ttatggattt gactgctcta ttgaggtatt cggtcatatc ggtaaaggtt acgtctacaa
     4021 cccagagttt aaggaaaaca ttgacaagtt tggttctgga acagcccagt acacgtcaga
     4081 tgccattgca gcttacgttc agacaaatgc agaaaaaata ggctaggaat ttcctagcct
     4141 attttttact tcaaatcata aagccagtcg tcaccgtttt tgtagtaaaa gaattcactg
     4201 agatcttctt ctagaaacac acgaagcata tcagacatat catcggttgc aagttttaga
     4261 tgagaaagat tttcaaagtc ctcccaccaa actttccctt cgtctgaaga ctggagttca
     4321 ccagtaaagt gttctgtctt gtaaaaaagg acgacataac gataatcctt gtcgtcatac
     4381 cagtttttga taccacagag ttggggtttg gaaatgatca gaccagtttc ttctttcact
     4441 tcacgaatga cagcatcgac aaaggattcg ccacgttcaa catgaccacc aggaaaagta
     4501 atgccaggcc agtcgggact aactcggtct tggaccagga ccttatctcc gtttttaatc
     4561 atacacatgt taacaaattc gactgcctct cttctgttca ttcttcacaa cctttaatct
     4621 ttaatcataa tgcagacttc ccgccaccca gccggtacag agggcagaag tgatgttaaa
     4681 gccacccgtg tgggcattga tatccataac ttcgcctgca aagtggaggc caggtaccag
     4741 cttactttca agggttttag gattgatttc cttgagactg actccaccct tggtaacaaa
     4801 ggactttgca agggacattt ttccagttac aggaatttta agttctttaa tggactggac
     4861 aagctgttct cgttcctttt cagtcagctg tttgactttt tcaggatatc cttgtacaaa
     4921 aaattcggcc aagcgttctg gtaacaaggt ttttaaagcg tttttcaagg atttttcccg
     4981 atttttttct agaaatgtaa ccaagtcctt ctcagaaagt tgaggcaaaa catcgagtga
     5041 gagaacctcc ccacctttga caaagctaga catgcgtagg gcagcaggac ctgacaaacc
     5101 aaagtgggta aagagtaaat catgagtgat gacatgctta ccataactta gggtcacatc
     5161 gtccaaagaa atcccttgta aggctttatg tggaaaatct gttaataaag gactttcagc
     5221 agcctcaaga tcggtgatgg tatgcttaaa atggcgagca atctcgtgac caaaaccagt
     5281 cgaaccagtc gaaggataag acttaccacc tgttgtgaca atgagtttct cacaagtgaa
     5341 ggtttgatcc gctgacttaa ggacaaactg gttatctact tttttaacag aaacgatttc
     5401 tatttgagta gcaacttgac cacctagttc ggtgattttc ttttccaaag cttcgataat
     5461 agtccgagac ttgtcactgg ctggaaagac gcgtccgtgg tcttcgacct taagtttaac
     5521 accattttct gtaaaaaagt tgatgatgtc atgattatcg aactgggaga aaacactgta
     5581 aagaaagcgt ccgtttccag gaattccagc tagcaggttg tctaagctac cattgttggt
     5641 cacattgcaa cgtcccccac cagtcccagc taattttttt ccaagtttcc gatttttttc
     5701 gatgaggagg gttttctgtc cataaaagct actggaaatc gtagccatca taccagcagg
     5761 tcccccaccg atgacaatag tatcaaaatg tttcatagct ctattgtacc acaaaaaaac
     5821 aagagatgat ggtcacctct tgtcaagaat gcaattaatc aatttcatag cccatcagca
     5881 aaccgccctc ttctgcatag aaactgcaga gaccagaggt tggtagaatt ttaatatccg
     5941 cttgtgggaa ggtttcacgg attcgctctg agagctgttg acaacatttt tcgttattgc
     6001 gttgggccat gacaatacgg ccaccagcat atccagcttt tactaactca tcataggcag
     6061 cttgaactga tttctttgat ccccttgctt tttgtagcaa ttcgagagtt ccagtttcac
     6121 tagcttttcc gaccatacga atgttgagaa ggccaacgac cgtaccgata agcttgctca
     6181 aacggccgtt cttcaccaag ttatcgactt tggctaggac aaagagcaac ttagtttttt
     6241 cttgataggc ggtgatagct tcaaccactt cttcaaaaga caagccttgg tcaatcaagt
     6301 cattcaattt ttctacgagt aggtcaactt caccaccagc agataaacta tcaatcacat
     6361 gaatcttagt gtcaggatgg tcttccagat aaatattctt tgctagttga gcactattgt
     6421 gactgccaga aagggtacct gtgatggtta ctaggaaaat gttttcggca ccttcaaatg
     6481 ctcgcaaata gtcatctggg cttggacaag ctgattttga agcttctgca gttgcataca
     6541 tggtttccat catttggtca atatcgagac tggcgtcatc aacaaagacc tgatcagcta
     6601 cttgaatggt taaggggaca cttacaaagg ttgtgttaat agctggtgtt ggcagttgac
     6661 gataatcaca accagagtca gcaataatct tccaagtcat agaaattctc catctttgtc
     6721 agttatacat tgacaaaggt tctgtctttt tttacaatta tatcatgaaa actcttgaaa
     6781 caaaagcatc atccgtctgt tgtgacaagt agaaagaaaa tgttatgtct gaacgtagaa
     6841 tctctgaaaa gtctcttgaa aatctcagaa aatcaaacca agaatccaat ttattaacca
     6901 gagaagccat tgaaacagcc ctcttgcaac tcttggaaaa aaaggagctg accaagatta
     6961 gtatttctga attggtcaaa cgtgcaggtg tttcgcgtgc ggccttttat cgcaattatg
     7021 actccaaaga ggaaatttta gagagcgtct ttaaacgaac tgtccacaat attatggaac
     7081 agctgcatca ttacgattta aagacagacc tttatttggt ttgggttcac cttttccggg
     7141 aggccagaaa ggaagctaga gtaattcaat tggccttgga ttaccatctg gaaaaaatct
     7201 ttgtccaagc catgcaggaa tttctagaaa aataccatgg gaaatcaaaa ggtgtcagct
     7261 cttatcttca ttccttctgg agctcagcca tcgtctctgt ccttctaaaa tggatcaagg
     7321 atggcatgaa ggtaccagct gaaaagattg cagatttagg tttaccattt tttaaaaaat
     7381 agagaaaaag gagaaaagag atgactgaaa aaagactggc ctgggatgag tattttgcag
     7441 cccaagccct actaattgcg aatcgttcca cttgtaaacg tgctaaagtg ggcgcgattc
     7501 tggtaaaaga taataaggtt atttccactg gttacaatgg ttcggtgtca gggactgagc
     7561 attgtattga tcacgaatgt ttggtcattg aaggccactg tgttcgcacc cttcacgctg
     7621 aggtcaatgc tatccttcaa ggtgctgagc gtggtgttcc caaaggcttt acagcctatg
     7681 taacccattt tccttgtctc aactgtacaa aacaattgct tcaggtcggc tgcaagcgcg
     7741 tggtttatat caaccagtac cgaatggacg actacgccca atacctttat caagaaaaag
     7801 ggacagaatt gacccattta ccacttgaga cagtacagac agctcttaaa gaggctgatc
     7861 taatgtaaaa attatcaaaa ataaatggct tagaaagatt tttaaaccgt tttttggtat
     7921 aataagaaga ataaattgaa agaaggaatt ccaaaaatgg gaaaaattga agttattaat
     7981 cacccactga ttcaacacaa attgtcaatc ttgcgtcgta cagatacttc tacaaaagct
     8041 tttcgtgagc tagtagatga gattgcaatg ttgatggggt atgaagtact tcgtgatctt
     8101 ccactagaag atgtggaaat cgaaacacca attacaaaaa cagttcaaaa acaattggca
     8161 ggtaagaaat tggccatcgt cccaatcttg cgtgcaggta tcgggatggt tgatggtctc
     8221 ttgagcttgg ttccagctgc taaagttggc cacatcggta tgtaccgtga tgaagaaaca
     8281 cttcaaccag ttgaatactt ggtgaaattg cctgaggaca ttgaccaacg tcaaattttt
     8341 gtagtagacc caatgttggc aacaggtggc tcagcaatct tggctgttga ttctcttaaa
     8401 aaacgtggcg catcaaatat caaatttgtc tgccttgtat ctgctccaga gggtgtaaaa
     8461 gcccttcaag aagctcatcc agatgtagaa atctttacag cagccttgga tgaacgtttg
     8521 aacgaacacg gttatatcgt tccaggtctt ggagatgctg gagaccgctt gttcggtaca
     8581 aaataagatc gaaaagaaga atgacttgga aaagtatttc cagtcacgaa aggaggttgg
     8641 gtttttgttt ctgtctaatg aaagcagagc aaaaatttga ccttttttga ccaagatatt
     8701 ataatagtct tatcttcagt catttgacca acaaaattaa aactcaaaag gagaaatgaa
     8761 tgattcctgt agttattgaa caaacaagcc gtggagaacg ttcttacgat atttactcac
     8821 gtcttctcaa agaccgcatc attatgctga caggtccggt tgaagacaat atggctaact
     8881 ctgttattgc ccaattgctt ttcttggatg cccaagatag tacaaaagat atttaccttt
     8941 atgtcaatac accaggtggt tctgtttcag ctggtttggc aatcgtagat accatgaact
     9001 ttatcaaggc agatgtccaa accattgtta tgggaatggc tgcatctatg ggaacagtca
     9061 tcgcatcaag tggagcaaaa ggcaaacgtt tcatgcttcc aaatgctgaa tacatgattc
     9121 accaaccaat gggcggtaca ggtggtggta cccaacaaac tgatatggct atcgctgcag
     9181 aacacttgct caaaactcgt aataccttgg aaaaaatctt ggctgaaaat tcaggtcagt
     9241 caatggaaaa agtccatgca gatgcagaac gtgataactg gatgagcgcc caggaaacac
     9301 ttgaatatgg ctttattgat gaaattatgg ccaacaattc attgaactaa tgatgataga
     9361 aggcaaactc gactgggttt gctttttttg gtataatagg gagagatttc ttagaaagag
     9421 gatttatcat gtttgaaaaa gtcaatcgct ctggcttgat tatctatctt tactataatc
     9481 gtgatgccaa aaaactgcag gattatggag atattaccta tcattccaag aaacatcgtt
     9541 acttacaact ctatgttcca actcaagaag tggagcaatt ggtcggacgc ttgagcaagg
     9601 aaaaatttat taaaaaagtt agggtttgtc atatccaaga gttggaaaca ccctttgtgg
     9661 gcaatcttta tcgataggaa aacgttatca tcgaaaaagt tcaaggaaaa cattgacaat
     9721 tttctgataa ttcggtatat tcttaacaga ctatttaaga aataaggaga caaaaagatg
     9781 aagaaaaaat ttgccctatc gtttgtggcg cttgcaagtg tagcacttct tgcagcctgt
     9841 ggagaagtga agtctggagc agtcaacact gctggtaact cagtagagga aaagacaatt
     9901 aaaatcgggt ttaactttga agaatcaggt tctttagctg catacggaac agctgaacaa
     9961 aaaggtgccc aattggctgt tgatgaaatc aatgccgcag gtggtatcga tggaaaacaa
    10021 atcgaagtag tcgataaaga taataagtct gaaacagctg aggctgcttc agttacaact
    10081 aaccttgtaa cccaatctaa agtatcagca gtcgtaggac ctgcgacatc tggtgcgact
    10141 gcagctgcgg tagcgaacgc tacaaaagca ggtgttccat tgatctcacc aagtgcgact
    10201 caagatggat tgactaaagg tcaagattac ctctttattg gaactttcca agatagcttc
    10261 caaggaaaaa ttatctcaaa ctatgtttct gaaaaattaa atgctaagaa agttgttctt
    10321 tacactgaca atgccagtga ctatgctaaa gggattgcaa aatctttccg cgagtcatac
    10381 aagggtgaaa tcgttgcaga tgaaactttc gtagcaggtg acacagactt ccaagcagcc
    10441 cttacaaaaa tgaaagggaa agactttgat gctatcgttg ttcctggtta ctataatgag
    10501 gctggtaaaa ttgtaaacca agcgcgtggc atgggaattg acaaaccaat cgttggtggt
    10561 gatggattca acggtgagga gtttgtacaa caagcaactg ctgaaaaagc atcaaacatc
    10621 tactttatct caggcttctc aactactgta gaagtttcag ctaaagctaa agccttcctt
    10681 gacgcttacc gtgctaagta caatgaagag ccttcaacat ttgcagcctt ggcttatgat
    10741 tcagttcacc ttgtagcaaa cgcagcaaaa ggtgctaaaa attcaggtga aatcaagaat
    10801 aaccttgcta aaacaaaaga ttttgaaggt gtaactggtc aaacaagctt cgatgcagac
    10861 cacaacacag tcaaaactgc ttacatgatg accatgaaca atggtaaagt tgaagcagca
    10921 gaagttgtaa aaccataata gaaaaatgtt gaaataggga atgagccttt gactcactcc
    10981 ctgtttcgat atttaatact cttcgaaaat ctcttcaaac tgcgtcaacg tcgccttgga
    11041 ttatatatgt gactgacttc gtcagtctta tctacaacct caaagcagtg ctttgagcaa
    11101 cctgcggcta gtttcctagt ttgctctttg attttcattg agtataagaa cctatcaaaa
    11161 agtgagggaa aaccctcgga attataaata gaaagagtga atcttatgct ccaacaactc
    11221 gtaaatggtt tgattctagg tagtgtttac gcgctgttag ccctaggata taccatggtt
    11281 tacggaatta tcaagctcat caacttcgcc catggtgata tttatatgat gggagccttt
    11341 atcggttatt tcttgatcaa ttctttccaa atgaatttct ttgtagcgct tattgtagct
    11401 atgctagtga cagctattct tggtgtcgtg attgagtttc ttgcttaccg acctttgcgc
    11461 cactctactc gtattgctgt tttgattacg gctattgggg tttctttcct attggagtat
    11521 ggaatggtct atctggttgg tgccaatacc cgtgccttcc ctcaagcgat tcaaacagtt
    11581 cgatatgatt tgggaccaat tagcttaaca aatgtgcagt taatgatttt ggccatttcc
    11641 ttgattttga tgattttgtt acaagtcatt gtccaaaaga ctaagatggg gaaagccatg
    11701 cgtgcagtat cagtagatag cgacgcggca caattgatgg ggatcaatgt aaaccgtacg
    11761 attagcttta ccttcgcttt gggttctgct cttgcgggtg cggctggtgt tctgattgct
    11821 ctttattata actctcttga gcctttgatg ggggttactc caggtcttaa atctttcgtt
    11881 gccgcagtac ttggtggtat cggaattatt cctggtgcgg ctcttggtgg ctttgtgatt
    11941 ggtctattgg aaacctttgc gacagccttt gggatgtcag atttccgtga tgccattgtt
    12001 tatggaatct tgttgttgat cttgattgtc cgcccagctg gtatccttgg taagaatgtg
    12061 aaagagaagg tgtaaacgat gaaggaaaat ttaaaagtta atattctatg gttactcctt
    12121 ttgttagctg gctatagctt gattagtgta ctggtttcag tcggagtact taatctattc
    12181 tatgtacaga ttttacaaca aattggaatt aatattattt tggctgttgg tctcaactta
    12241 atcgttggtt tttcaggaca attttcactt ggtcatgctg gtttcatggc gattggtgcc
    12301 tatgcagcag ctattattgg ttctaaatca ccaacctacg gtgccttctt tggagctatg
    12361 cttgtagggg ctttgctttc aggagcagtt gccttacttg tcggcattcc aaccttgcgc
    12421 ttgaaggggg actatcttgc ggtagcaact ctaggtgttt ctgaaattat ccgcatcttt
    12481 atcatcaatg gtggaagcct tacaaatggt gcggcaggta tcttagggat tcctaacttt
    12541 acaacttggc aaatggttta cttctttgtc gtgattacaa ccattgcaac cttgaacttc
    12601 ttgcgtagcc caattggtcg ttcaaccctc tctgttcgtg aagatgaaat cgctgctgag
    12661 tcagttgggg ttaatacgac taaaattaaa atcatcgctt ttgtctttgg tgccattact
    12721 gcaagtattg ctgggtcact tcaggcagga tttatcgggt ctgttgtacc gaaagattac
    12781 accttcatca actcaatcaa cgttttgatt attgttgtat ttggtggact cggttccatt
    12841 acaggtgcgg ttgtttcggc tattgttctg ggaattttga atatgcttct ccaagatgtt
    12901 gctagtgtgc gtatgattat ttacgctttg gccttggtat tggtaatgat tttcagacca
    12961 ggtggactcc ttggaacgtg ggaactgagc ctatcacgtt tctttaaaaa atctaagaag
    13021 gaggaacaaa actaatggca ttacttgaag taaaacagtt aaccaaacat tttggtggtc
    13081 taacagctgt tggagatgtg actcttgaat tgaacgaagg ggaactggtt ggattaatcg
    13141 gtccaaacgg agctgggaaa accacccttt tcaacctttt gaccggtgtt tatgaaccaa
    13201 gcgagggaac agtaacccta gatggtcacc ttttgaatgg gaaatcacct tataagattg
    13261 cctctttggg acttggacgt actttccaaa atatccgtct ttttaaagat ttaacagttt
    13321 tagacaatgt tttgattgct tttggaaacc atcacaaaca gcatgttttt actagtttct
    13381 tacgcttacc agttttttac aagagtgaaa aagaattaaa ggctaaagct ttggaattgt
    13441 tgaaaatctt tgatttagat ggtgatgcag agactcttgc taaaaatctt tcctacggac
    13501 aacaacgtcg tttggaaatt gttcgtgccc ttgctacgga acctaaaatt ctcttcttag
    13561 atgaaccagc agcaggtatg aacccacagg aaacagccga attgactgag ttaattcgtc
    13621 gtatcaaaga tgaatttaag attacaatca tgttgattga acacgatatg aatctggtca
    13681 tggaagtaac agaacgtatc tacgtacttg aatatggccg tttaattgct caaggaactc
    13741 cagacgaaat taagaccaat aaacgcgtta tcgaagctta tctaggaggt gaagcctaat
    13801 gtctatgtta aaagttgaaa atctttctgt gcattacggt atgatccaag cagtccgtga
    13861 tgtaagcttt gaagttaatg aaggagaagt tgtttccctt atcggtgcca atggtgcagg
    13921 taagacaact attcttcgca ccttgtcagg tttggttcga ccaagttcag gaaagattga
    13981 atttttaggt caagaaatcc aaaaaatgcc agctcagaaa atcgtggcag gtggtctttc
    14041 acaagttcca gaaggacgcc acgtctttcc tggcttgact gttatggaaa atcttgaaat
    14101 gggagctttc ttaaagaaaa atcgtgaaga aaatcaagct aacttgaaga aggttttctc
    14161 acgctttcct cgtcttgaag aacggaagaa ccaagatgca gctactcttt caggagggga
    14221 acaacaaatg cttgccatgg gacgcgctct tatgtcaaca ccaaaacttc ttcttttaga
    14281 tgaaccatca atgggacttg ccccaatctt catccaagag atttttgata tcattcaaga
    14341 tattcagaag cagggaacaa ccgtcctctt gattgaacaa aatgccaata aagcacttgc
    14401 aatctctgac cgaggatatg tattggaaac aggaaaaatc gtcctatcag ggacaggaaa
    14461 agaactcgct tcatcagaag aagtcagaaa agcatatcta ggtggctaaa acaatccaga
    14521 ggattgtttt agccggcaga tggagattac gaagtaatca tcaatatagt ccgggggacc
    14581 tttttagtcg gtagattgag attgcaaaca aatatgcatc tacattgaaa gcttaatttc
    14641 taataattga aaaaatcgaa tgaaaaattt cttaccttca ttcacagagc tctatttcag
    14701 agctcttttt gctagcttat tcatactttt ctgaatttcg aaaaagaaat gtaagcgttt
    14761 gatagatttg caaaaagatt gtataatagg gataagaata gaaaaggaga agtctcatgg
    14821 cagttaaaga ttttatgacc cgcaaggtag tttatattag tccagataca acagtatctc
    14881 atgcagcaga tttgatgaga gagcaaggtt tgcaccgtct gcctgttatc gaaaatgatc
    14941 aattagttgg tttggtgact gagggaacca ttgcacaagc aagtccatct aaagcaacaa
    15001 gtctttctat ctatgagatg aattatcttc tgaataagac aaaagtaaaa gatgtcatga
    15061 ttcgcgatgt tgtcactgtc tcaggctatg ctagtctaga agatgcaact tatctgatgt
    15121 tgaaaaataa gattagtatt ctccctgtcg tagataacca tcaagtatac ggagttatta
    15181 ctgaccgtga cgttttccaa gcctttcttg aaattgcagg ttatggcgaa gaagggattc
    15241 gtgtacgctt tgttacagaa gatgaagttg gtgttcttgg aaaaattgtt tctttgattg
    15301 tagaagaaaa tttgaatatc tcccatacag tcaatattcc gcgtaaggat ggtaaggtga
    15361 ttatcgaagt gcaaatcgat ggatcaattg atttaccagc cttgaaagaa aaatttgaag
    15421 caaatggtat tcaagtggaa gaaatcgctc gcacttcagc aaaagtcttg taagaaggga
    15481 agcccaaagg cttctttttt catgaaaagg ggattagaga aaaagatgga aagaaatgat
    15541 aaaatatgct ataatgaaat aatgtaaaaa aggagtattt atggacattt cagtaattcg
    15601 tcagaaaatt gacgcaaatc gtgaaaaatt agcttctttc agggggtctc tttgacctcg
    15661 aagggctaga ggaagagatt gccatcttgg aaaacaagat gacagaacct gatttttgga
    15721 acgataatat tgcggcccaa aaaacgtcgc aagaattaaa tgaattaaaa aacacttaca
    15781 ataccttcca taagatggaa gagttgcagg atgaagtcga aattttattg gattttttgg
    15841 ctgaagacga gtcagtgcat gatgaactgg tagcgcagtt agccgaactt gataagataa
    15901 tgaccagcta cgagatgact ctactcttgt cagaacctta tgaccacaac aatgccatct
    15961 tggaaatcca tccaggttct ggtggtactg aggcgcagga ctggggtgat atgttgcttc
    16021 gtatgtatac tcgttatggt aatgctaaag gctttaaagt ggaagtgttg gattaccaag
    16081 caggtgatga ggctggtatt aagtcggtaa ctttatcatt tgaagggcct aatgcctatg
    16141 gtctcctcaa gtcagaaatg ggtgttcatc gcttagtgcg aatctcacca tttgactctg
    16201 ccaaacgtcg ccatacctct ttcacatctg tagaagtgat gccagaattg gatgatacta
    16261 ttgaagtgga aatccgtgaa gatgatatca agatggatac cttccgttca ggtggtgccg
    16321 gtggacaaaa cgtcaataaa gtttcaacag gtgtacgttt aacccacatt ccaactggaa
    16381 ttgttgtcca atcaacagtg gatcgtaccc agtatggaaa tagagatcgt gccatgaaga
    16441 tgttgcaggc taagctctat caaatggagc aagataagaa ggctgcggag gtagattctc
    16501 tcaaaggtga gaaaaaggag atcacttggg gaagccaaat ccgttcttat gtcttcacgc
    16561 cttatactat ggtaaaagat caccgaacta gctttgaggt tgctcaggta gataaggtta
    16621 tggatgggga cctagatggt tttatcgatg cttatctcaa gtggcgaatt agctaagata
    16681 gaaaggaact cacatgtcaa ttattgaaat gagagatgtc gttaaaaaat acgacaacgg
    16741 aacgactgct ctacgcggtg tttcggtcag cgttcaaccg ggggaatttg cttacatcgt
    16801 aggaccttca ggagcaggga agtcaacttt tattcgttct ctgtatcgtg aagtaaaaat
    16861 cgataaagga agcctatcag ttgctggttt taatctggtt aagatcaaaa agaaagatgt
    16921 cccgcttcta cgtcgtagtg ttggggttgt cttccaggat tataaattgt taccaaagaa
    16981 aactgtctat gaaaatattg cttacgctat ggaagtaatc ggggaaaatc gccgtaatat
    17041 caaaaaacga gtgatggaag ttttggactt ggttggattg aagcataagg ttcgttcttt
    17101 cccaaatgaa ctctcaggtg gggagcaaca gcggattgcg attgcgcgtg caattgtaaa
    17161 taatcccaaa gtattgatag ctgatgagcc aacaggaaat ctggatccgg ataattcatg
    17221 ggaaattatg aatctcttgg aacggattaa cctacaaggg acaactattt tgatggcgac
    17281 tcataatagc cagattgtaa ataccttgcg ccaccgtgtc attgccattg aaaatggccg
    17341 tgtcgttcgt gacgaatcaa aaggagagta tggatacgat gattagtaga ttttttcgcc
    17401 atttatttga agccttaaaa agtttgaaac gaaatggttg gatgacagta gctgctgtca
    17461 gttcagtcat gattactttg accttggtgg caatatttgc atctgttatt ttcaatacag
    17521 cgaaactagc tacagatatt gaaaataatg tccgtgtagt agtttatatc cgaaaggatg
    17581 tggaagataa tagtcagaca attgaaaaag aaggtcaaac tgttacaaat aatgactacc
    17641 acaaggtata tgattctttg aagaacatgt ctacggttaa aagtgttacc ttttcaagta
    17701 aagaagaaca atatgaaaaa ttaaccgaga taatgggaga taactggaaa atctttgaag
    17761 gagatgccaa tcctctctat gatgcctata ttgtagaggc aaacgctcca aatgatgtaa
    17821 aaactatagc cgaagatgct aaaaaaattg aaggtgtctc tgaggttcaa gatggcggtg
    17881 ccaatacaga aagactcttc aagttagctt catttatccg tgtttgggga ctagggattg
    17941 ctgctttgtt aatttttatc gcagttttct tgatttcaaa taccattcgt attaccatta
    18001 tttcccgcag tcgcgaaatt caaatcatgc gcttggtcgg agctaaaaac agttatatcc
    18061 gtggaccgtt cttgttagaa ggagccttta tcggtttatt gggagctatc gcaccatctg
    18121 ttttggtctt tattgtttat caaattgttt accaatctgt caacaaatcg ttggtagggc
    18181 aaaatctatc catgattagt ccagatttat ttagtccgtt gatgattgcc ctactatttg
    18241 tgattggggt tttcattggt tcattgggat caggaatatc catgcgccga ttcttgaaga
    18301 tttaggtaaa atagctgctt ttatgaggag attgtaaaat ctcctttttt gctacaagag
    18361 tttttgaaaa gagatgcgta gaagaaaaga gcttccaaag aagtccccca gagaagactt
    18421 cttgatggct aatttgaact tgaaatttgg cgcactagaa attttttaga aaaaagtgta
    18481 atttttttat aaaagccttt acaaaaaaaa ttaaagtggt ataattaaat catagaaggt
    18541 gcaaacgttt tcgtaaaacg tttgcctaaa taaaaataaa ggagatttga atgatgaaag
    18601 atacattcaa aaatgtcttg tctttcgaat tttggcaaaa attcggtaag gctttgatgg
    18661 tagttatcgc ggttatgccg gctgctggtt tgatgatttc aatcggtaag tctatcgtga
    18721 tgattaaccc aacctttaca ccacttgtca tcacaggtgg aattcttgag caaatcggtt
    18781 ggggggttat cggtaacctt cacattttgt ttgccctagc cattggagga agctgggcta
    18841 aagaacgtgc tggtggtgct ttcgccgctg gtcttgcctt tatcttgatt aaccgtatca
    18901 ctggtacaat ctttggtgtg tcaggcgata tgttgaaaaa tccagatgct atggtaacta
    18961 ctttctttgg tggttcaatc aaagttgctg attactttat cagtgttctt gaagctccag
    19021 ccttgaacat gggggtattc gtagggatta tctcaggttt tgtaggggca actgcttaca
    19081 acaaatacta caacttccgt aaacttcctg atgcactttc attcttcaac gggaaacgtt
    19141 tcgtaccatt tgtagttatt cttcgttcag caatcgctgc aattctactt gctgctttct
    19201 ggccagtagt tcaaacaggt atcaataact tcggtatctg gattgccaac tcacaagaaa
    19261 ctgctccaat tcttgcacca ttcttgtatg gtactttgga acgtttgctc ttgccatttg
    19321 gtcttcacca catgttgact atcccaatga actacacagc tcttggtggt acttatgaca
    19381 ttttaactgg tgcagctaaa ggtactcaag tattcggtca agacccacta tggcttgcat
    19441 gggtaacaga ccttgtaaac cttaaaggta ctgatgctag tcaataccaa cacttgttag
    19501 atacagtaca tccagctcgt ttcaaagttg gacaaatgat cggttcattc ggtatcttga
    19561 tgggtgtgat tgttgctatc taccgtaatg ttgatgctga caagaaacat aaatacaaag
    19621 gtatgatgat tgcaacagct cttgcaacat tcttgacagg ggttactgaa ccaatcgaat
    19681 acatgttcat gttcatcgca acacctatgt atcttgttta ctcacttgtt caaggtgctg
    19741 ccttcgctat ggctgacgtc gtaaacctac gtatgcactc attcggttca atcgagttct
    19801 tgactcgtac acctattgca atcagtgctg gtattggtat ggatatcgtt aacttcgttt
    19861 gggtaactgt tctctttgct gtaatcatgt actttatcgc aaacttcatg attcaaaaat
    19921 tcaactacgc aactccaggg cgcaacggaa actacgaaac tgctgaaggt tcagaagaaa
    19981 ccagcagcga agtgaaagtt gcagcaggct ctcaagctgt aaacattatc aaccttcttg
    20041 gtggacgtgt aaacatcgtt gatgttgatg catgtatgac tcgtcttcgt gtaactgtta
    20101 aagatgcaga taaagtagga aatgcagagc aatggaaagc agaaggagct atgggtcttg
    20161 tgatgaaagg acaaggggtt caagctatct acggtccaaa agctgacatt ttgaaatctg
    20221 atatccaaga tatccttgat tcaggtgaaa tcattcctga aactcttcca agccaaatga
    20281 ctgaagcaca acaaaacact gttcacttca aagatcttac tgaggaagtt tactcagtag
    20341 cagacggtca agttgttgct ttggaacaag taaaggatcc agtatttgct caaaaaatga
    20401 tgggtgatgg atttgcagta gaacctgcaa atggaaacat tgtatctcca gtttcaggta
    20461 ctgtatcaag catcttccca acaaaacatg cttttggtat tgtgacggaa gcaggtcttg
    20521 aagtattggt tcacattggt ttggacacag taagtcttga aggtaaacca tttacagttc
    20581 atgttgctga aggacaaaaa gttgcagcag gagatctcct tgtcacagct gacttggatg
    20641 ctatccgtgc agcaggacgt gaaacttcaa cagtagttgt cttcacaaat ggtgatgcaa
    20701 ttaaatcagt taaattagaa aaaacaggtt ctcttgcagc taaaacagca gttgctaaag
    20761 tagaattgta atatacttga ggttggaagc tgtattccaa cctcttattt tgggagaaaa
    20821 gaatgaaatt tttaacactc aatactcaca gttggatgga gaaagaagca gaggaaaaat
    20881 tccagatttt gcttgaagat attcttgaaa aggactatga tttgatttgt ttccaagaaa
    20941 tcaatcagga gatgacctcg tcagaggtgg aggttaatga cctttatcaa gctttgccag
    21001 cagctgagcc tattcaccaa gaccattatg ttagactctt ggttgaaaag ttgttagagc
    21061 aagggaaaaa ttactactgg acctgggctt ataaccatat cggctatgac cgctaccatg
    21121 aaggtgtggc tatcttgtct aaaacaccta ttgaagccag agaaattttg gtttcagatg
    21181 tggatgatcc aacagactat catactcgcc gtgttgccct agctgaaact gtagtcgatg
    21241 gcaaggagct agcagttgcc agtgttcatc tctcttggtg ggataaaggt ttccaagaag
    21301 aatgggcacg atttgaggct gtcttgaaaa aattgaacaa gccactttta ctagctggag
    21361 attttaacaa cccagcaggt caggaaggtt accaagctat tttagctagt ccattaggct
    21421 tacaagacgc atttgaagtt gctcaagaga aaagtggtag ctatactgtt ccgcctgaaa
    21481 ttgatggctg gaaagggaac actgaacccc ttcgaatcga ttatgtcttt actaccaaag
    21541 agttagcggt ggaaaattta catgtcgtat ttgatggtaa caagagtcca caagtgagtg
    21601 atcactatgg cttgaatgcg gtattaaatt ggaaataaaa tcaaaaaatg aaagggagcg
    21661 agtcctttca tttttttaca aaaatcccta taattactat tttggagaag gagttttttg
    21721 tatatttgta tattatgagg aaatatccac aaataagttt ttaaaacttt acggtcaaaa
    21781 aaaaatcgct aatattaact atttatgata gaatgaaaat tatgaaataa aaggaggact
    21841 ggaatgtttt ttcaggatag aaagataaaa tattcaatcc gcaaattgtc agttgctact
    21901 gtgtcccttg cgattggatt tttgtttgcg cctgcggcgc ttggagtcgc tcaagtagct
    21961 caagctgatg agctttcaac tactgaacaa gtggagaata aagcagagaa tcaggtctcg
    22021 gtggtctctt ttgcaacaga gcaagaagaa agtgaaacga cttatgttga tacgacgaat
    22081 aaagtgactt ggacatttgc aggatacgat aaagaaaaaa ttgttgtagg aaaaggcaga
    22141 cagactttcc ttggaagctg ggtacctact ccaaatccag aatatgtatt caaatcatct
    22201 aaagcaggtg ttccattacc acaaagtatt ttgggaatgc ttccaaagga tgaagcttct
    22261 tataaggttg gtgacaccat tgtagccaaa caacctgctg tagaatcagt agtcgaagaa
    22321 gaaaaagact atgtctggac cttcaaaggt tatgatcaga agaatgcgac gtacaatggc
    22381 aagcgtgtga catttacagg tatctgggaa gtaacgccta gaccgcatca tgtaagctat
    22441 acttttgtaa gtgttacatc tggtgttgat ttgcctaaat ttatccagaa gaaagcacca
    22501 aaagatggct caacttactt caataggacg agagtttttg cagaagagcc gacaacaaag
    22561 acctacatag atagtgtgaa cgatggcaca tggaccttca agggttatga cgcagctagc
    22621 gccgttgtta acaaggctaa tgtagagttt gtaggtaagt gggaattcaa gg
//
LOCUS       DAVMCG010000028        22532 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVMCG010000028 DAVMCG010000000
VERSION     DAVMCG010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.029"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            93..362
                     /gene="blpJ"
                     /locus_tag="VYP66_001370"
     CDS             93..362
                     /gene="blpJ"
                     /locus_tag="VYP66_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HEV1850916.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            431..661
                     /gene="blpU"
                     /locus_tag="VYP66_001371"
     CDS             431..661
                     /gene="blpU"
                     /locus_tag="VYP66_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1850917.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            664..783
                     /locus_tag="VYP66_001372"
     CDS             664..783
                     /locus_tag="VYP66_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1850918.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            1080..1241
                     /locus_tag="VYP66_001373"
     CDS             1080..1241
                     /locus_tag="VYP66_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850919.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIVYMIAVMIYF
                     SLIKKKEKK"
     gene            1251..1622
                     /locus_tag="VYP66_001374"
     CDS             1251..1622
                     /locus_tag="VYP66_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850920.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLTSIL
                     VTVYLTREMRLREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            2251..2634
                     /locus_tag="VYP66_001375"
     CDS             2251..2634
                     /locus_tag="VYP66_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1850921.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2686..3375
                     /locus_tag="VYP66_001376"
     CDS             2686..3375
                     /locus_tag="VYP66_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1850922.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRELLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3417..3650
                     /locus_tag="VYP66_001377"
     CDS             3417..3650
                     /locus_tag="VYP66_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850923.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3801..4412
                     /locus_tag="VYP66_001378"
     CDS             3801..4412
                     /locus_tag="VYP66_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1850924.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4574..5368
                     /locus_tag="VYP66_001379"
     CDS             4574..5368
                     /locus_tag="VYP66_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1850925.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5365..6000
                     /gene="trmB"
                     /locus_tag="VYP66_001380"
     CDS             5365..6000
                     /gene="trmB"
                     /locus_tag="VYP66_001380"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1850926.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6126..6605
                     /gene="rimP"
                     /locus_tag="VYP66_001381"
     CDS             6126..6605
                     /gene="rimP"
                     /locus_tag="VYP66_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1850927.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            6649..7785
                     /gene="nusA"
                     /locus_tag="VYP66_001382"
     CDS             6649..7785
                     /gene="nusA"
                     /locus_tag="VYP66_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1850928.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7807..8100
                     /locus_tag="VYP66_001383"
     CDS             7807..8100
                     /locus_tag="VYP66_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1850929.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8093..8392
                     /locus_tag="VYP66_001384"
     CDS             8093..8392
                     /locus_tag="VYP66_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1850930.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIEDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8409..11174
                     /gene="infB"
                     /locus_tag="VYP66_001385"
     CDS             8409..11174
                     /gene="infB"
                     /locus_tag="VYP66_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1850931.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAEPVAPKTEKVAAKPQSRNFK
                     AEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNRRFNDQAKKQ
                     QGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEERFKQYQAAKE
                     ALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKKQARPDKNRD
                     DYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTPKPVTERKFH
                     ELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGETIELLMVDYG
                     IEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTLLDTLRNSRV
                     ATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDITILVVAADDG
                     VMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTAWGGDSEFVE
                     ISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAVATLLVQQGT
                     LNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGDHFAVYEDEK
                     SARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADVQGSVEALSA
                     SLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQARQQAEADDVE
                     IRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIGGFMVINGKV
                     ARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDIKMDDVIEAY
                     VMEEIKR"
     gene            11425..11775
                     /gene="rbfA"
                     /locus_tag="VYP66_001386"
     CDS             11425..11775
                     /gene="rbfA"
                     /locus_tag="VYP66_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1850932.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            12054..12833
                     /locus_tag="VYP66_001387"
     CDS             12054..12833
                     /locus_tag="VYP66_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850933.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMVITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            12835..13017
                     /locus_tag="VYP66_001388"
     CDS             12835..13017
                     /locus_tag="VYP66_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850934.1"
                     /translation="MNPIKAFAKIYGNYFLTMQGVKVMKTIKKDDNVVVGLGKLFIAD
                     KLMDAARWLIKPEERE"
     gene            complement(13374..13448)
                     /locus_tag="VYP66_001389"
                     /pseudo
     CDS             complement(13374..13448)
                     /locus_tag="VYP66_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            13479..13712
                     /locus_tag="VYP66_001390"
     CDS             13479..13712
                     /locus_tag="VYP66_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1850935.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13712..15046
                     /locus_tag="VYP66_001391"
     CDS             13712..15046
                     /locus_tag="VYP66_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1850936.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIADESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            15056..15310
                     /locus_tag="VYP66_001392"
     CDS             15056..15310
                     /locus_tag="VYP66_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1850937.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15406..15801
                     /locus_tag="VYP66_001393"
     CDS             15406..15801
                     /locus_tag="VYP66_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1850938.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            16345..16662
                     /locus_tag="VYP66_001394"
     CDS             16345..16662
                     /locus_tag="VYP66_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000440279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850939.1"
                     /translation="MERLGVHYEISERTQIPILDACPLVLDCRVDRIVEEDGICHIFA
                     KILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKD
                     GKN"
     gene            16649..17209
                     /locus_tag="VYP66_001395"
     CDS             16649..17209
                     /locus_tag="VYP66_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1850940.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            17209..17787
                     /locus_tag="VYP66_001396"
     CDS             17209..17787
                     /locus_tag="VYP66_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1850941.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            17780..20431
                     /locus_tag="VYP66_001397"
     CDS             17780..20431
                     /locus_tag="VYP66_001397"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1850942.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ITRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAINPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            20501..21256
                     /locus_tag="VYP66_001398"
     CDS             20501..21256
                     /locus_tag="VYP66_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEV1850943.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            21539..22342
                     /locus_tag="VYP66_001399"
     CDS             21539..22342
                     /locus_tag="VYP66_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1850944.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQARGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADMVKKIQHFISGIWQIHPFREGNARTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(22458..>22532)
                     /locus_tag="VYP66_001400"
     CDS             complement(22458..>22532)
                     /locus_tag="VYP66_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1850945.1"
                     /translation="YNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         6823 a         4046 c         5058 g         6605 t
ORIGIN      
        1 taagaaaatc aaaaagatac tataaaaaat ctatttgttt attgaattta agactttggt
       61 aacaaattga aaataaaaag gaggtattca tcatgaatac aaaaatgttg tcacagttag
      121 aggttatgga tactgaaatg cttgcgaaag ttgaaggggg gtatagctcc actgattgtc
      181 aaaatgcact gattacagga gtcactacgg gaattataac tggtggaact ggagcaggtt
      241 tggccacttt aggagtagct ggacttgctg gtgcatttgt tggagcacac attggtgcaa
      301 ttgggggtgg attaacatgc ttaggaggta tggttggtga taaattggga ctaagttggt
      361 aagacttata gtaaaattat gaggattcta ttctgattta ttttagtttt ttaaaaaagg
      421 agtatttgtc atggatacaa aaatgatgtc acaattttct gttatggata ctgaaatgct
      481 tgcttgcgtt gaaggtggcg gatgcaattg gggagatttt gccaaagcag gtgttggagg
      541 agcagcagca agaggtcttc aactaggcat taaaacagga acatggcaag gtgcagcaac
      601 tggtgctgcg ggtggagcta tacttggagg tgtagcctat gcagcaacat gttggtggta
      661 attatggatt ttaaaagttt tattattggt ttagtagttg gtatatttgg tccttatatg
      721 gataatttaa ttagaaaaat attttcaaaa tttcccaaaa aggatacaga tagtaccccc
      781 taaaaaataa atttttcccc tgtatttgct agcttaattt acaggggagt ttctttaata
      841 ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa aagtctacaa acaagttggt
      901 atcaatacaa tataaagagg aaagtatgtt tttcatgctt gcttttttaa tttttacaat
      961 tcaagaggtt ttgatgacca tttatgattt gagtgatcca aggtcaaaat aagtgctata
     1021 ctagcagtgt aaatgttctt gctcaactaa gataaatcgc acatttagga ggaaatctta
     1081 tgaagaaaaa aatactgatt attttcgttc tgtatctaat catgtccatc tttctatatc
     1141 cgcttaggga gagtgcttgg tatcagctat tttataccat agtctatatg attgcggtta
     1201 tgatctattt ttctttaatt aaaaagaaag aaaagaaatg aaagattttc ttgattaaaa
     1261 agaatcatat tctttgtgag attgttcctg ggtcagttgc ctttgcttgt ttctacttat
     1321 ctatttctat ttcgtcagtt ttccaatttc ttttagtggt tattaacttg acttctattt
     1381 tggttactgt ttatcttact agggaaatga gattaagaga gtttgaagat gatgatttgg
     1441 ttagtcctag aaccaatcaa ctcatgttta tcggcttgac aggctttatg tctattattt
     1501 gtttgtatag agggatcaca gcaggagaat cctaccaaca aataattgcc tacattggcg
     1561 ctattctctg cttgaccatc atgcttctgc tcatttgggg attgaagtat tataaaaagt
     1621 agaggctaat gcagtttttg caatttaaga tgtcttgatg acaattcaag atttggatga
     1681 aaaactttga caaatagtgc tatactgaaa ttgtcaaagt tgcaacgggt gctgctacat
     1741 tatgttaaaa atcgctcttg attgataagc tggatttgtt aggaaaggag taaataatta
     1801 tggataagaa aaagatagtt tcgactataa tatgtatagt atttcttgta gtgtcagtag
     1861 ataatttttt tagagactta accccgttac tgttcatttt aaatattatt ggtctgtctt
     1921 gcttttcagt gctaacatac actaacataa aagagatact cttaaatata agtaaatgat
     1981 gatttggtta gtcctagaac caatcaactt atgtttatcg gcttggcaga ttttatgttt
     2041 gtcatttgtt tgtatagagg tatttcagaa acagaattct atcaacaact aatcgtttat
     2101 ataggtgtat tctctgcttg tttatcacgc ttctgctcat gtggggcttg aagtattata
     2161 aaaagtagct ttctatcctt ttctgacagg atatttgagt agaaggctct attaaattgt
     2221 tagtgaaata aatgaatgga ggtatttaat atgaaataca gattattttt tgttattttc
     2281 ttgagtagtg tgttggatat tcttttaggg acatttttac aaatctctat cgtatctatt
     2341 gggtggcttg ttctttacag tggtttgttt gaagcaggag ttttccttct tgctaataaa
     2401 ggggtggcgg taaaaatcaa ggaagtagat attcgaaatc gctttaaatt tatttttgga
     2461 aaaaccttat ggtttcaaat tcttttgctc atctttttga taatcaaact ttatcttggt
     2521 ttggatgcga ggttgatttt attctatgga catattttca ttgtctttaa tgccttaatg
     2581 tatctattat ctagtagtca ggttagcctt aaaaaaaaca aactgtcttc ttaatcttac
     2641 agcagtagag cctgacaagg tgaggtcata gtagggagga tttctatgaa aaagtatcaa
     2701 cttctattca aaataagtgc agtcttctct tacttatttt tcgtatttgg tctttctcag
     2761 ctgacgctta tcgtccaaaa ttattggcaa ttttcttccc agattggtaa tttcgtctgg
     2821 attcaaaata tcttgagttt actttttatt ggagtcatga ttgtggttct tgttaagaca
     2881 ggccatggtt atctcttccg cattccaaga aaaaaatggc tttggtattc gattttgaca
     2941 gtattagtgg tagtgttcca gatctctttt aacgttcaga cagctaaaca tgttcagtca
     3001 actgcggaag gttgggctgt attgattggt tatagtggga ctaactttgc agagctaggt
     3061 atttatatag ccctgttctt tctggttcca ctgatggaag agttaatcta tagagaatta
     3121 ctgcaacatg ctttctttaa gcattcgcga tttggtcttg atttgcttct tccttctatt
     3181 ttatttgctc tccctcattt ttcaagcctg cctagtctgt tagatatctt cgtctttgca
     3241 acagttggaa tcatctttgc tggtttgacc cgctatacca agagcattta tccatcctat
     3301 gcggtgcatg tgatcaataa tattgtagcg accttcccgt ttttgctcac ttttctacat
     3361 agggtcttgg ggtaaaaaaa caaaaggctt gcttttcagc catagaggag gtcatcatgt
     3421 ataaacactt atttttccta gattccaaaa ctttagatcg gttgacaccc tatattctag
     3481 tcttggcttc tgacaccatt gcttttaatg tttttgtgct aacctttgta tctgcggtgg
     3541 tttttaattt cctaaattcc atgctagctt taatggctat attcataggg gctggctatg
     3601 tggtcggatt ttggttacta atactcaatg aaaatcaaag agcaaactag gaaactagcc
     3661 gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg tttgaatttg attttcgaag
     3721 agtataaaat ggtttgtttt ggaaaggcta gaactaaaga atgacgtgta ggaagtctgt
     3781 ttgttgagga ggataatttt atggagtttt ttgataaatt tcatgccttg tgttttggat
     3841 ttttagtact aataattgtc attatagttc cttatacgat taaccatggg gatttttttc
     3901 aaaatgaatc tgcattgatt cttgtaagtc ttcttgtaac ctcgctgagt gttgcttatg
     3961 ctagaaagtt tgaaatgatt tcttttggga tgttaagcaa gaaacaactt ttgcttttca
     4021 ttgcaatctt tcttctaagt gtacttgaga cgctggttta tattcatttc ttcgctgttt
     4081 cttctggctc aggggtccaa cacttggcgg aagtcagcag aggaatttcc ctgtctttga
     4141 ttttgactac ctcagttttt ggccccatcc aggaggaact cattttcaga ggacttcttc
     4201 aaggtgcggt ttttgacaat tcttggttag ggcttgtgct aacttcctct ctcttttctt
     4261 tcatgcatgg accttctaat gtcccttcgt ttatttttta tctacttggg ggcttgttgc
     4321 tgggccttgc ttataaaaag agccaaaact tatgggtttc tactctagtc catatgcttt
     4381 acaacagttg gccactctta tattatttat aaaaatcatg aaaaggtaag taggagattg
     4441 tgcttacctt tttctttcta taatgataac ccaaaccact ccagaggctt ttctttgaga
     4501 atcgggttag agtggttgac gaataggcca aaaactagta gaatagtaag gaaactttat
     4561 acggaggaaa gaaatggatt tgggtgataa tgagctaaca ctgactccca tacctgggaa
     4621 aagtggcaag gcttatatgg gtagctatcc tgatgggaag cgcatctttg taaaaatgaa
     4681 cacctctcca atcctacctg gtctagctag agaacaaatt gctccacaat tattatggag
     4741 tcgtcgtttg gcagatgggc gtgatatgtg tgctcaagaa tggttgacag gcaagatatt
     4801 gaccccctat gatatgaatc gtaagcaaat cgtcaatatt ttaacccgtc ttcatcgctc
     4861 acgtccgttg atgacacaat tgagtcgttt gggctatgcc atggaaacac ctgtagattt
     4921 actacagtct tggcaagaaa cggctccaga tgctttgcgt aaaaatcatt ttatcagtga
     4981 agtgatggct gatttacgtc agactattcc aggatttaga gaggaccatg cgaccattgt
     5041 ccatggagat gtacgacata gtaattggat tgagacagat agtggcttga tttatttagt
     5101 agattgggat tcggttcgct tgaccgatcg catgtttgat gtggcccata tgctctgcca
     5161 ttatatttca gaacatcagt ggaaggaatg gttgacctac tacggttaca agtacaatca
     5221 aacggtatta agtaaattgt attggtatgg tcaattgtct tatttgagtc agatttccaa
     5281 gtattatatg aaccaagatt tagaaaatgt caatcgggag attcatggtt tgcgtcattt
     5341 ccgagacaag tatggaaaga gaagatgaga gttagaaatc gtaaaggggc aacagaatta
     5401 ctagaggcaa atccccagta tgtggtcctc aatcccttgg aagccaaggc aaaatggcgg
     5461 gacttgtttg gcaatgataa tcccattcat gtggaagttg gaagtggaaa gggtgccttt
     5521 gtttcaggta tggccaagca aaaccctgac atcaactata tcgggattga tattcaaaag
     5581 tctgttttga gctacgcttt ggacaaggtg cttgaagttg gagtgcctaa catcaagctc
     5641 ttgtgggtag atggttctga cttgactgac tactttgaag acggtgagat tgatcgcttg
     5701 tatctgaact tttcagatcc atggccgaaa aaacgccatg aaaagcgtcg tttgacctac
     5761 aagacctttt tggatacctt caaacgtatc ttgcctgaaa atggagaaat tcatttcaag
     5821 acggataacc gtggcttgtt tgagtacagt ttagtgagct tttctcaata tggcatgaaa
     5881 ctcaatggtg tctggctaga tttgcatgcc agtgattttg aaggcaatgt catgacagaa
     5941 tacgagcaaa aattctcaaa caaggggcaa gttatctacc gagttgaggc agaattttaa
     6001 gagatagcct aaaattaggc tgtacaagtg cttttgcttt acataagttg gcaaacgtgc
     6061 tatactgata gtaagaatat gaaaagtgag gcggggaaat atcttcgcct cttgcttatg
     6121 aggaggtgga cgcaatcgca acaatcgtag aattagtcag agaagttgta gaacctgtca
     6181 tagaagctcc ttttgaactc gtggatatcg agtatggaaa gattggcagt gacatgattc
     6241 tcagtatttt tgtagataaa cccgaaggaa ttaccttgaa cgacacggca gacttgacag
     6301 aaatgatcag tcctgtccta gacaccatca agccagatcc cttcccagaa caatatttcc
     6361 tagaaattac cagtccaggt ttggaacgtc ctttgaaaac caaggatgcc gtcgctggag
     6421 cggttggaaa atacatccat gtcgggctct accaagccat cgataagcaa aaggtctttg
     6481 aaggaacctt gttggccttc gaagaggacg agttgactat ggaatatatg gacaagacgc
     6541 gtaagaaaac cgtccaaatt ccatacagtt tagtatcaaa agcacgttta gcagttaaat
     6601 tatagaaaaa gaaaggatag cttttgagga ttcaaaagtg aagaaaacat gagtaaagaa
     6661 atgctagagg ccttccgcat tttggaagaa gacaagggaa tcaaaaaaga agatatcatc
     6721 gacgcagtag tagagtcgct tcgttccgct tatcgcagac gctatggtca gtcagacagc
     6781 gtagctattg acttcaacga aaaaacaggt gactttacag tttatactgt ccgtgaagtt
     6841 gttgatgaag tatttgatag ccgtttggaa atcagcttga aagatgctct tgccattaat
     6901 tcagcttatg aacttggaga caaaatcaag tttgaagaag caccagctga gtttggtcgt
     6961 gtagcagccc aatctgccaa acaaaccatc atggaaaaaa tgcgcaagca aacacgtgcc
     7021 atcacttaca atacttacaa agaacatgag caagaaatca tgtctggtac agtagaacgc
     7081 tttgacaacc gctttatcta tgtcaacctt ggtagcatcg aagcccaatt gtcaaaacaa
     7141 gaccaaattc ctggagaagt ttttgcttct catgatcgta tcgaagttta tgtttacaag
     7201 gttgaagaca accctcgtgg tgtgaacgtc tttgttagcc gtagccatcc agaaatgatc
     7261 aaacgtttga tggagcaaga aattccagaa gtttatgatg gaactgttga aatcatgagc
     7321 gtggctcgtg aagcaggtga ccgtacgaag gttgctgttc gtagccacaa tccaaacgtg
     7381 gatgctatcg gtacaatcgt tggacgtggt ggtgctaata tcaagaagat tactagcaaa
     7441 ttccacccag ctcgttacga tgctaaaaat gaccgcatgg taccaatcga agaaaatatc
     7501 gatgttatcg agtgggtagc agatccagct gaatttatct acaatgccat cgctcctgct
     7561 gaggttgacc aagttatctt tgatgaaaac gacagcaaac gtgccttggt ggttgttcca
     7621 gataacaagc tttctcttgc cattggtcgt cgtggacaaa acgtgcgctt ggcggctcac
     7681 ttgactggtt accgtatcga tatcaagtct gctagcgaat ttgaagccat ggaagacgct
     7741 gcttcagtag agttggaagt agaaaacgat actgtagaag aataaaagct gctagaggag
     7801 ggaaagatga aaacaagaaa aatccctttg cgcaagtctg ttgtgtctaa cgaagtgatt
     7861 gataagcgtg atttgctccg cattgtcaag aacaaggaag gacaagtctt tattgatcct
     7921 acgggcaagg ccaatggccg cggcgcttat atcaaactag acaatgcaga agccctagag
     7981 gcgaaaaaga agaaggtctt taaccgcagc tttagcatgg aagtggaaga aagcttttat
     8041 gacgagttga tcgcttatgt ggatcacaaa gtgaaaagaa gagagttggg acttgaataa
     8101 gcaaaagata agtaatctct tggggcttgc tcagcgagca gggcgcatca tatcgggtga
     8161 agaattggtg gtcaaggcca ttcaagacgg caaggccaag ttggtctttc tagctcatga
     8221 tgctggaccc aatctgacca agaagattga agataaaagt cattattatc aagtagaaat
     8281 tgtaaccgtg ttttcaacac tggaattaag catagcagtc gggaaatcga gaaaggtttt
     8341 ggctgtaaca gatgctggat ttacaaagaa aatgaggtct cttatggaat agaagaggag
     8401 gacatgattt gtctaagaaa agattgtacg aaatcgcaaa agaacttgga aaagaaagta
     8461 aagaagttgt agcgcgtgca aaagagttgg gcttggatgt gaaaagccac tcatcaagtg
     8521 tggaagaagc tgtcgctgca aaaattgctg ccagctttaa gcctgcagct gctccgaaag
     8581 tagaagcaaa acctgcagca ccaaaagtaa gtgcagaaaa gaaagccgaa aaatctgagc
     8641 cagctaaacc agctgagcca gtcgctccga aaacagaaaa agtagcggct aaaccgcaaa
     8701 gtcgtaattt caaggctgag cgtgaagcac gtgctaaaga gcaggcagag cgacgcaagc
     8761 aaaataaggg caataaccgt gaccaacaac aaaacggaaa ccgtcagaaa aacgacggcc
     8821 gtaatggtgg aaaacaaggt caaagcaacc gcgacaatcg tcgctttaat gaccaagcta
     8881 agaagcagca aggtcagcaa aaacgtagaa atgagcgccg tcagcaagag gataaacgtt
     8941 caaatcaagc ggctccacgt attgacttta aagcccgtgc agcagcccta aaagcagagc
     9001 aaaatgcaga gtacgctcgt tcaagtgagg aacgcttcaa gcagtatcag gctgctaaag
     9061 aagccttggc tcaagctaac aaacgcaagg aaccagagga aatctttgaa gaagcggcta
     9121 agttagctga acaagcacag caagttcaag cagtggttga agtcgtccct gagaaaaaag
     9181 aacctgcagt ggatacacgt cgtaaaaaac aagctcgacc agacaaaaat cgtgacgatt
     9241 atgatcatga agaagatggt cctagaaaac aacaaaagaa tcgaagtagt caaaatcaag
     9301 tgagaaatca aaagaatagt aactggaata acaacaaaaa gaacaaaaaa ggcaataaca
     9361 agaacaaccg taatcagact ccaaaacctg ttacggagcg taaattccat gaattgccaa
     9421 cagaatttga atatacagat ggtatgaccg ttgcggaaat cgcaaaacgt atcaaacgtg
     9481 aaccagctga aatcgttaag aaacttttca tgatgggtgt catggccaca caaaaccaat
     9541 ccttggatgg ggaaacaatt gaactcctca tggtggatta cggtatcgaa gccaaacaaa
     9601 aggttgaagt ggataatgct gacatcgaac gtttctttgt cgaagatggt tatctcaatg
     9661 aagatgaatt ggttgagcgt ccaccagttg ttactatcat gggacacgtt gaccacggta
     9721 aaacaaccct tttggatact cttcgtaact cacgtgttgc gacaggtgaa gcaggtggta
     9781 ttactcagca tatcggtgcc taccaaatcg tggaaaatgg taagaagatt accttccttg
     9841 atacaccagg acacgcggcc tttacatcaa tgcgtgcgcg tggtgcttct gttaccgata
     9901 ttacgatctt ggtcgtagcg gcagatgacg gggttatgcc tcagactatt gaagccatca
     9961 accactcaaa agcagctaac gttccaatca tcgtagccat taacaagatt gataaaccag
    10021 gtgctaaccc agaacgcgtt atcggtgaat tggcagagca tggtgtgatg tcaaccgctt
    10081 ggggtggaga ttctgaattt gttgaaatct cagctaaatt caaccaaaat atcgaagaat
    10141 tgttggaaac agtccttctt gtagctgaaa tccaagaact caaggcagac ccaacagtgc
    10201 gtgcaatcgg tacggttatc gaagcgcgct tggataaagg aaaaggtgcg gtcgcaaccc
    10261 ttcttgtaca acaaggtacc ttgaatgttc aagacccaat cgttgtcgga aataccttcg
    10321 gtcgtgtccg tgctatgacc aacgaccttg gtcgtcgtgt taaagttgct ggaccatcaa
    10381 caccagtctc tatcacaggt ttgaacgaag caccgatggc gggtgaccac tttgccgttt
    10441 acgaggatga aaaatctgcg cgtgcagcag gtgaagagcg tgccaaacgt gccctcatga
    10501 aacaacgtca agctacccaa cgtgttagcc ttgaaaacct ctttgatacc cttaaagctg
    10561 gggaactcaa atctgttaat gttatcatca aggctgatgt acaaggttct gttgaagccc
    10621 tttctgcctc acttcaaaag attgacgtgg aaggtgtcaa agtgactatc gtccactcag
    10681 cggtcggtgc tatcaacgaa tcagacgtga cccttgccga agcttcaaat gcctttatcg
    10741 ttggtttcaa cgtacgccct acaccacaag ctcgtcaaca agcagaagct gacgatgtgg
    10801 aaatccgtct tcacagcatt atctacaagg ttatcgaaga gatggaagaa gctatgaaag
    10861 ggatgcttga tccagaattt gaagaaaaag ttattggtga agcggttatc cgtgaaacct
    10921 tcaaggtgtc taaagtggga actatcggtg gatttatggt tatcaacggt aaggttgccc
    10981 gtgactctaa agtccgtgtt atccgtgatg gtgtcgttat ctatgatggt gaactcgcaa
    11041 gcttgaaaca ctataaagac gacgttaagg aagttacaaa cggccgtgaa ggtggattga
    11101 tgatcgacgg ctacaatgat attaagatgg atgatgtgat tgaggcgtat gtcatggaag
    11161 aaatcaagag ataagatttt ttgctccttt cttaggtggt gagggacgca agcaaaccga
    11221 tggtttcatt gcttattttt gagcctaggg tctcaaaaat cccctgtgat gggactgata
    11281 aatcagttcc atcactttca ccacggcgaa agaagcagat gacttcaaat tgaacttcgt
    11341 ttcaatttaa actgaaaatc aagaagttta aaatagctag gtctgctggc ctagcttttg
    11401 gttcaaagta gagaaaggaa tatcatggca aatcatttcc gtacggatcg tgtgggcatg
    11461 gaaatcaagc gtgaagtcaa tgagattttg caaaagaaag tccgtgatcc acgtgtccaa
    11521 ggtgtgacca tcacagatgt tcagatgctg ggtgacttgt ctgttgccaa ggtttattac
    11581 accattttga gtaaccttgc ttcggataac caaaaagccc aaatcgggct tgaaaaagca
    11641 actggtacca tcaaacgtga acttggtcgc aatttgaaat tgtacaaaat cccagatttg
    11701 accttcgtca aagacgagtc catcgagtat ggaaacaaga ttgacgagat gctacgcaat
    11761 ctggataaga actaaagaag aggggttgcc cctctttttt ggtggaggaa aataggttga
    11821 atttgaaatg gaaaaatatt cttttataat agattgaaac tagaatagta cgcctctact
    11881 tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttgtcctg ttcttgtttc
    11941 attttaatat aaaaaagggg ttctgtattt tttaatgtta tctaattaga aaatgctttt
    12001 tttgtaggaa atataatatg ataaggtgta aaaaagaaat aaggagtttg tatatggctg
    12061 aacaagactt agctatgcaa gtattacaac aagtggtaaa actaccagtt gttaaggttg
    12121 atcgttcgaa atttttagtg gataagtttt ccaaagaatt gggtccacag gacattccta
    12181 ccttattgga acaaggtcca acgtctctct tatctcaaga aatcttagat cgagtggcta
    12241 atgcctgtat tagggataat gttttattag cgagtgggac ttctgttttg gcaggattac
    12301 ctggagggct tgctatggta attaccattc cagctgatgt ggctcaattt tatggtttct
    12361 ctctgaaatt ggctcaagaa ttaggttata tttatggtta tgaggatctt tgggcttcac
    12421 gcgaggagtt gagtgaagat gctcaaaata ccctcttgct ttatctaggc gtaatgttgg
    12481 gggtgaatgg aaccgctgcc ttgctacgtg ctggtggtat aacaattgcc aaacaggtaa
    12541 tgaaaacagt gcctaataaa gctttaacaa agacgctttg gtatcctatt ttgaaaaaag
    12601 tcttaaaaat atttggtgtg aatcttacca agggagggct ggccaaagga atggggaaat
    12661 tcattcctat cttgggtggt atcatttcag gtggtttaac ctttgcaact atgaaaccga
    12721 tgggtgaaag cttgcagaaa gaattgtcta aactagtcaa ctatagtgaa gttcaatatc
    12781 aagaagatgt tgaaacaatc cgaaaagagg ctgaaataat cgagggtgag tgagatgaat
    12841 cctatcaaag cttttgctaa aatttatggt aattactttt tgaccatgca aggtgtaaaa
    12901 gtaatgaaaa cgataaagaa agatgacaat gtcgttgtcg gtctagggaa actttttatt
    12961 gcagacaagt taatggatgc ggctcgatgg ctcatcaagc cagaggagag agaatgaaat
    13021 tttttttggc aattcttgcc attcttttta ttaaaccgat tattgggatt gtgaaattct
    13081 tttggatgat tatctctttt gcagttcaat tgctgtttta caagctatta tttaaaatat
    13141 tggattggct ctttaaactt atttagatgg taatcaaaat cgcagagaac tagcaggaac
    13201 tctactgcta gttttttaat ctctttccat atggtataat ataagcagta aaatcatttt
    13261 atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgcagtata tatgttactg
    13321 acttcgtcag ttctatccac aacctcaaaa cggtgttttg agctgacttc gtcagttcta
    13381 tctacaacct caaaacactg ttttgagcaa cctgcggcta gctttctagt ttgctctttg
    13441 attttcattg agtattagaa catataatgg aggtcgtcat ggacaatatc atcgatgtgt
    13501 caattcctgt tgcagaagtg gtggacaagc atccagaagt cttggaaatt ctagtggagc
    13561 tgggttttaa accccttgcc aatcccttga tgcgcaatac agttggtcgt aaagtatcac
    13621 ttaaacaagg ttctaagcta gcaggaactc ctatggacaa gattgtacgc acactggaag
    13681 cgaatggcta cgaagtgatt ggattagact aatggcagat gaacggattc atgtcctacg
    13741 ggatatttta ttagaattgc ataatggcgc ctctcctgag tcggttcagg agcgttttga
    13801 tgcgaccttt gcgggtgtct cagccattga gatttccctt atggagcacg agctgatgaa
    13861 ctcggattcg ggcgtcactt ttgaagatgt tatggaactc tgtgatgtcc atgccaatct
    13921 ttttaaaaat gctatcaaag gtgtcgaagt tttagatacc gaacaccctg ggcacccagt
    13981 tcgtgtcttt aaggaagaaa atttggccct ccgtgcagct ttgattcgca ttcgtagatt
    14041 gttagatacc tatgagtcta tggaagacga ggaaatgctt gcggagatgc gcaagggctt
    14101 ggtgcgtcag atgggacttg tggggcaatt tgacatccat taccaacgta aggaagaact
    14161 cttctttcct atcatggagc gctatggaca cgattcacct cccaaagtta tgtggggagt
    14221 ggatgatcag attagggaac tctttcaaac agctctaacg acagccaagt cactaccaga
    14281 agtgtcaatt agcagtgtaa aggaagcttt tgaagctttt gcgacagagt ttgaaagtat
    14341 gattttcaag gaagagtcca tcctcctcat gattctcctt gagtctttta ctcaggatga
    14401 ctggcttcag attgcggatg agagcgatgc ctatggctat gccatcatcc gtccgtcaga
    14461 gaaatgggtg ccagaacgac agagctttat tgaggaaaag attgcagagg agcctgtaca
    14521 gctagatacg gcagaaggtc aagttcaaca agtcatagat acgccagaag gccattttac
    14581 cattaccttt acccctaagg aaaaggaagc tgtgctggac cgccatagtc aacaggcttt
    14641 tggtaatggc tatctttcag tcgagcaggc caatctcatc ctcaatcatc tccctatgga
    14701 gattaccttt gtcaataaag aagatatttt ccagtattac aatgacaata cgccagctga
    14761 tgagatgatt ttcaaacgga cgccgtccca agtcgggcgc aatgtcgaac tctgtcatcc
    14821 gcctaagtat ttggacaagg tcaaaactat catgaagggg cttcgtgagg ggaccaagga
    14881 caagtatgaa atgtggttca agtctgagtc gcgaggtaag tttgtccaca tcacctatgc
    14941 tgcagtacac gatgaagacg gagaattcca aggagtgttg gagtatgttc aggatatcca
    15001 gccctaccgt gagattgata cggactattt tcgtggatta gaataaggag aaaaaatgag
    15061 ttacgaacaa gaatttatga aggaatttga agcttgggtc aatacccaaa tcatgattaa
    15121 cgacatggcg cacaaggaaa gtcaaaaagt ttacgaagaa gaccaggacg agcgtgccaa
    15181 agatgccatg attcgctacg agagtcgctt ggatgcttat cagttcttgc ttggtaagtt
    15241 tgaaaacttc aaagcaggca agggattcca tgatttgcca gaaggcttgt ttggtgagcg
    15301 aaattattaa acgagaaaga ttcttgattt ttcactaaaa tcttgataga atgtttatgt
    15361 taaatccttg tcagagcagg gattttttat tgaaaggatt ttatcatgtc aaagaaactc
    15421 aatcgtaaaa aacaattacg aaatggcctc cgtcgcgcag gtgccttttc aagtactgtg
    15481 actaaggttg tagatgagac aaaaaaagtc gtgaagcgtg cagaacagtc agcaagcgca
    15541 gctggtaagg ctgtttctaa aaaagttgaa caagcagtag aagctaccaa agagcaagct
    15601 caaaaagtag ctaattctgt agaagatttt gcagcaaact tgggtggact tccacttgat
    15661 cgtgccaaaa ctttctatga tgaaggaatc aagtctgctt cagatttcaa aaactggact
    15721 gaaaaagaac tccttgcctt gaaaggaatc ggcccagcta ccatcaagaa attgaaagaa
    15781 aatggcatca agttcaagta atttttcttg agccttgcat ttccgagaaa aacttgctac
    15841 aatagagcca ttagaggtgt tttgaatccc acattttaca gaaagtggcg gcgctgagaa
    15901 gtccacaaat gtgtcaaaac tggttgctaa tgactgaaaa aatgaaatat ttctgtcttt
    15961 ttattttaaa gactaaagat gcgggcttgg cccgaaattg ggtggtaccg cggataaaca
    16021 cattcgtccc tgtcatgtag atggcagggc ttttcttttg tgtcttagtc aaaggaggtt
    16081 gttataaaac aatcatttaa aactaataaa ctatattatg gttttcctgt ttttatttta
    16141 ggatatcaag attagaattt tggctataac atcacgacct gtagttcctc ttatagtcta
    16201 ggagattggg ttgtgattgg agtcgttgcg agagagaatg ccgcagagca gatcaaacag
    16261 tatcaaaaat ttactgtgaa tatttctgat gaaacttcta tgcttgcgat ggagtaggct
    16321 ggttttatca gtcatcagga gaaattggaa cgtttgggag tgcattatga aatttctgaa
    16381 cgaactcaga ttcctatttt agacgcctgt ccacttgttt tagattgtcg ggtagatagg
    16441 attgttgagg aagacggtat ttgccacatc tttgccaaga ttcttgagcg acttgttgcc
    16501 ccagaactcc tggatgaaaa gggacatttt aaaaatcaac tgtttgcccc aacctatttc
    16561 atgggagatg gatatcagcg cgtttatcgc tatctggaca agcgtgtaga tatgaagggc
    16621 agtttcatca aaaaagcgag gaagaaggat ggcaagaact gagctgccag ataaaatcga
    16681 aacagaacgt ctcgttttac gagtccgtac tgtggcggat gctgaggata tctttgacta
    16741 tgctagtttg ccagaggtcg cctatccagc aggttttcct ccagtcaaga ccttggaaga
    16801 tgagatttat tatctggagc acattcttcc ggagcgtaat caaaaggaaa atctcccagc
    16861 aggctacggg attgtcgtca aaggaacgga taagatcgtt ggctctatct atttcaacca
    16921 tcgccatgaa gatgatgtga tggaaatcgg ctatacctta cactcagact attgggggcg
    16981 aggttatgtg ccagaagctg cgcgtgcctt gattgactta gcctttaaag atttgggtct
    17041 tcacaagatt gaactaactt gctttggata taaccttcaa agtcaacgag tcgcggaaaa
    17101 gcttggcttt accctcgaag ctcgcataag agaccgtaaa gatgctcaag gcaactgctg
    17161 tgatgatttg agatatgcct tgctgaagag tgagtgggag gtgatttgat gcatcttttc
    17221 atcattggtg ctccagcatc aggaaaaatg accattggtc aagaattatc tcgactgacg
    17281 gatgctaccc tattttataa ccatcaagcc attgattttg cactagaaat ctatcaggac
    17341 tatacagagg aaatgtggga atttgttcgt ggaatcactt tttcattcct tggagcaagt
    17401 gcaagaaatc agcgatcagt aattttaaca gatgtaattg atttttcaaa tcagtatcag
    17461 ctgatgtatt taaagcaaat tcagaatttg ttggatgatt atcatcaaga gattcttttt
    17521 gttgagttgg aaacaagtct tgaagagtgc atacgtcgaa atcgaacgga gaatcgatta
    17581 aagtacaaac ccttaaaacg acatattgag gtatctgaaa gagaaatttt agagaccgct
    17641 gaaacacttc aattaaattc ccaatatcaa ccgaatgagt tgcaccacta ctttaaaata
    17701 aataatacga atttgtctgc agaagaagct gctaagcaaa ttcaaaataa aataaacaaa
    17761 atagagaaag gacacacaca tgtctaaaga actttcatct aaatacaatc cagccgaggt
    17821 tgaggctggt cgttaccaaa aatggcttga tgcggatgtt ttcaagcctt caggcgatca
    17881 aaaggctaag ccttattcaa tcgtgattcc accaccaaac gtaactggga aacttcacct
    17941 tggtcacgct tgggatacga ctttgcagga tatcatcatc cgtcaaaaac gcatgcaggg
    18001 ctttgatacc ctttggcttc caggtatgga ccacgctggt attgcgactc aggctaaggt
    18061 tgaggagcgc ttacgtggtg agggtattac gcgttatgac ctaggtcgtg agtctttctt
    18121 gacgaaggtc tgggaatgga aagacgaata tgccactacc atcaaggaac aatggggcaa
    18181 gatggggctt tctgtagact attctcgtga gcgtttcact cttgacgaag gtttgtcaaa
    18241 agctgttcgt aaggtctttg tggaccttta caagaaaggc tggatctatc gtggtgagtt
    18301 tatcatcaac tgggacccag cagctcgcac agccctttct gatattgagg tgattcacaa
    18361 ggatgtagaa ggtgccttct accacatgaa ttacatgctg gaagatggtt cacgcgccct
    18421 tgaagttgct acaactcgtc ctgagactat gtttggggac gttgcggttg cgattaatcc
    18481 agaagacccg cgctacaagg acttgattgg taaaaacgtc atccttccaa tcgctaataa
    18541 actcatccca atcgttggag atgagcacgc agatcctgag tttggtactg gtgtcgtgaa
    18601 aatcacacct gcccacgatc caaatgactt cttggttggc caacgtcata acttgccaca
    18661 agtcaacgtc atgaacgacg acggaactat gaatgagctt gcctttgaat tttcaggcat
    18721 ggatcgtttt gaagctcgta aggcagtcgt tgctaagttg gaagaaatcg gtgcccttgt
    18781 caaaatcgaa aaacgtgtcc attcagtcgg tcactcagaa cggacaggtg tcgtagttga
    18841 gccacgcttg tctactcaat ggttcgtcaa gatggaccaa ttggctaaga acgccattgc
    18901 caaccaagac acagaggaca aggtcgaatt ctacccacct cgtttcaacg ataccttcct
    18961 tcaatggatg gaaaatgtcc acgactgggt tatctctcgt cagctttggt ggggtcacca
    19021 aatccctgcc tggtacaatg ctgatggtga aatgtatgtc ggcgaagaag ctccagaagg
    19081 tgacggatgg actcaggacg aagacgtctt ggatacttgg ttcagttctg ccctctggcc
    19141 attttcaacc atgggctggc ctgaagtcga ctcagaagac tttaaacgtt atttcccaac
    19201 ttcaaccttg gtaacaggtt acgacatcat cttcttctgg gtgtctcgta tgatcttcca
    19261 gtcattggaa ttcacaggcc gtcaaccatt ccaaaacgtc cttatccacg gtctcattcg
    19321 tgacgagcaa ggacgcaaga tgtctaagtc tctcggtaac gggattgacc caatggatgt
    19381 tatcgagaaa tacggtgccg atgcccttcg atggttcctt tcaaacggtt ctgcgccagg
    19441 acaagacgtg cgtttctctt atgagaaaat ggatgcttca tggaacttta ttaacaagat
    19501 ttggaacatt tctcgctata tcctcatgaa caatggaggt ttgacgctgg atgtggcgca
    19561 tgacaatgtc acaaaagttg caacaggtga ggctggtaat gtgacggacc gctggattct
    19621 ccacaatctc aacgaaacca ttgcaaaagt tactgaaaac tttgataagt tcgagtttgg
    19681 tgtggctggt catatccttt acaacttcat ttgggaagaa tttgccaact ggtatgttga
    19741 gttgaccaag gaagtccttt atagcgataa cgaagaagag aaagtcatca cacgttctgt
    19801 tctactatac actttggaca agatccttcg tctccttcac ccaatcatgc cattcgtgac
    19861 agaggaaatc tttggacaaa tctcagaagg ttctatcgtg acagctgcat acccaactgt
    19921 taatctagcc tttgaagacc ttgcggctca cactggtgtg gaaagtctca aagacttgat
    19981 tcgtgctgtt cggaatgcgc gtgcggaagt aaatgtagca ccaagcaagc ctatcaccat
    20041 ccttgttaag acaagcgata gcgacttgga agccttcttt aacagcaatg tcaactatat
    20101 caaacgcttt acaaatccag aacacttgga aatcgcatca accatccctg cacctgaact
    20161 ggctatgtca agcgttatta caggagccga aatcttcttg ccactggccg atctcctcaa
    20221 tgttgaagaa gaactagctc gtctcgacaa agaactcgct aaatggcaaa aagaactgga
    20281 catggttggt aagaaactct ctaacgaacg cttcgtcgcc aacgctaaac cagaagttgt
    20341 ccaaaaagaa aaagacaaac aagccgacta ccaagccaag tatgatgtga ccgtagcacg
    20401 tattgatgag atgaagaagt tggtgaaata aacacagaaa cacggtgatg agccgtgttt
    20461 tttggtataa tgaaatcaat atctattgat ggagaaagtg atgtccaaac accctcatta
    20521 tgaattgtta aatttaattg gctacggtct tgccaagttt gacaagcttt ttataaaaga
    20581 atttcaatgc tctagcaagt cggagtttta tcgctatgtg gtttctctgg gaattgctga
    20641 aacaactgga gttgtaaaaa atagaatgga tttatttgat ccttattttg acaataatcg
    20701 aaaaggttgg tggcagaaag ctgaagttta tcgttttcgt aaagatttaa ttgatatgat
    20761 gtttggaaat gaagatgttc atagttatgc tgaaatagtt aaaatgttac ttgccagtga
    20821 agggaagaaa acaggcataa ccatcgttga aaaaccaata gttcgaacta aattcaaacg
    20881 tctacaggaa acgggaatgg aggctgagaa ttattttatc cttcattttg ataaagaaga
    20941 aaaattccaa ggtggacagt taaccgatgc ccgtctttat ggtgatggat atgactttca
    21001 ggtagatgtc caagagtatt cttaccttgc cgaagtaaaa ggtatccgaa aatctaaggg
    21061 gcgtgtgcgt ttaactgcaa aagaatttga aaaagtcaag gagtttcaat cggattttat
    21121 tttatccttg gtcacaaatc tagatgatat tccaaagtta gtgttaatcg ataatccttt
    21181 aaaacatttt gagtttaaaa agaatattat caaaaatgaa atcattgaat atagaagcgt
    21241 agaggatttg tattagttcc cccttaactt ttccagttga aggaacgaga agtcttgata
    21301 ggtcaacgac ttaatgaact ggaaatcaac ggtattcgtt tgactaagtt ttaagatggc
    21361 gaaatcggta ttgaatttat cagtagtgct gattataact cttttattat ttacatgaag
    21421 tatatatata tatatatatc atagaaccta ttgtgaggac tttttatagt ttaagccagt
    21481 ttccaaccaa tttcgtgatt tactggtaat gaagaaaaac aattgaaagg atatttctat
    21541 gcaaccaact tacaacattg acaatccaaa cttgtcttat gaagctaagc gtgatttatg
    21601 gcggataggt tttggtctgc agaaagttga caatctagtg ccatcagctt atatggaatc
    21661 tttggctgag aaacaggctc ggggtgaact gacttatgag caggtttatg aggatgcaac
    21721 ggcttatcac catactattg atgcaagtac ggaggaggca gacttggttt ctctacgcat
    21781 tgtagaacta ttgtctcgaa gaggctttag cttcagtcct gcgaccttac ttgctattca
    21841 taaggagttg tttcaagata tatttgaacc ctcgattccg gtaggtcaat ttcgtcagac
    21901 taatatcaca aagaatgaac ctgttttgaa tggtgaaagt gttgtgtact ctgattactc
    21961 catgattcaa atgacattgg attatgattt taatcaggaa aaacaagttg catatgcgac
    22021 actaacccag gcggatatgg ttaaaaaaat ccagcatttt atttcaggaa tctggcagat
    22081 tcatccattt cgcgaaggaa acgctcggac agtaacggtc tttttgattc agtatcttcg
    22141 tgagtttggt tttgatattg ataatatacc atttcagcaa cattccaagt attttcgtga
    22201 tgccttggta ttagataatg caaagatttt acagcgacgt cctgagtttt taacagcttt
    22261 ttttgaaaat ctcttgctcg gtggtcaaaa tgatttgtct tcagaaaaaa tgtatctaga
    22321 tttagacctc gatttttcat aatccaaata ctgagtaaac attgaatttt aggaaaaaat
    22381 gaagtaaaca ttcccacaat aaaacgcata gtatcaagtg ttaaaatgta ctgcccccca
    22441 aaagttagac aattaattta tccgaaggat ttagttctgt attgcacagg gctaagtcct
    22501 tttagtttta ccttaattct cttattgttg ta
//
LOCUS       DAVMCG010000029        22173 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVMCG010000029 DAVMCG010000000
VERSION     DAVMCG010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.030"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(127..1146)
                     /gene="adhP"
                     /locus_tag="VYP66_001401"
     CDS             complement(127..1146)
                     /gene="adhP"
                     /locus_tag="VYP66_001401"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1850946.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1485..2297)
                     /locus_tag="VYP66_001402"
     CDS             complement(1485..2297)
                     /locus_tag="VYP66_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1850947.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2487..3905
                     /locus_tag="VYP66_001403"
     CDS             2487..3905
                     /locus_tag="VYP66_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1850948.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTDEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            3958..4665
                     /locus_tag="VYP66_001404"
     CDS             3958..4665
                     /locus_tag="VYP66_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1850949.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            4760..5734
                     /gene="folP"
                     /locus_tag="VYP66_001405"
     CDS             4760..5734
                     /gene="folP"
                     /locus_tag="VYP66_001405"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1850950.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGKFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5736..7058
                     /locus_tag="VYP66_001406"
     CDS             5736..7058
                     /locus_tag="VYP66_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1850951.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDSPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            7039..7593
                     /gene="folE"
                     /locus_tag="VYP66_001407"
     CDS             7039..7593
                     /gene="folE"
                     /locus_tag="VYP66_001407"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1850952.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7636..8448
                     /gene="folK"
                     /locus_tag="VYP66_001408"
     CDS             7636..8448
                     /gene="folK"
                     /locus_tag="VYP66_001408"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1850953.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8598..8915)
                     /locus_tag="VYP66_001409"
     CDS             complement(8598..8915)
                     /locus_tag="VYP66_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1850954.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9272..9718
                     /gene="rplM"
                     /locus_tag="VYP66_001410"
     CDS             9272..9718
                     /gene="rplM"
                     /locus_tag="VYP66_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1850955.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9737..10129
                     /gene="rpsI"
                     /locus_tag="VYP66_001411"
     CDS             9737..10129
                     /gene="rpsI"
                     /locus_tag="VYP66_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1850956.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(10390..10812)
                     /locus_tag="VYP66_001412"
     CDS             complement(10390..10812)
                     /locus_tag="VYP66_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1850957.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            10959..11135
                     /locus_tag="VYP66_001413"
     CDS             10959..11135
                     /locus_tag="VYP66_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850958.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            11536..13749
                     /locus_tag="VYP66_001414"
     CDS             11536..13749
                     /locus_tag="VYP66_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1850959.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSIPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(13971..14447)
                     /locus_tag="VYP66_001415"
     CDS             complement(13971..14447)
                     /locus_tag="VYP66_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1850960.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            14670..17873
                     /locus_tag="VYP66_001416"
     CDS             14670..17873
                     /locus_tag="VYP66_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1850961.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIIGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFNNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESGNPYKVYVNDKEASLTEQEKDYPETQSVFLESFDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            18226..18612
                     /gene="tnpA"
                     /locus_tag="VYP66_001417"
                     /pseudo
     CDS             18226..18612
                     /gene="tnpA"
                     /locus_tag="VYP66_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557980.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(18988..19617)
                     /locus_tag="VYP66_001418"
     CDS             complement(18988..19617)
                     /locus_tag="VYP66_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1850962.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISKIAQQYVTLR"
     gene            complement(19627..20628)
                     /locus_tag="VYP66_001419"
     CDS             complement(19627..20628)
                     /locus_tag="VYP66_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1850963.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(20659..21300)
                     /locus_tag="VYP66_001420"
     CDS             complement(20659..21300)
                     /locus_tag="VYP66_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1850964.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEIAAYLKEVLAK"
     gene            complement(21319..22134)
                     /locus_tag="VYP66_001421"
     CDS             complement(21319..22134)
                     /locus_tag="VYP66_001421"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1850965.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRIPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         6650 a         4052 c         4877 g         6594 t
ORIGIN      
        1 taaaaaattt ttatttttgt atgttgatat gttgagtttt tgaggagtaa tcttgaattc
       61 ttatttaaaa tttaatataa aaaagttgga agaagcttcc aacttttaaa ataggtttct
      121 attagattag tgggtgaagt cgagtaccat acgtccttgg atttggcctt tttccatttc
      181 gtcgaaaatg gcaacagcat cttctactgg acgtttttga acaactggga ctaccagacc
      241 ttctgcacca aattggaagg cttcttctaa gtctttacga gttccgacaa gagaaccgat
      301 gacttggatt ccatcgagga ctgttttaac gatgctgagt tccatcgttt cagaaggaag
      361 accaacagcg acgacgcgac caccagcacg aatggagtca acagcctggt tgaaggcaac
      421 tttagacaca gcagttacga cagctgaatg agctcctcca tcagtttttt ctttaatgag
      481 tccagctaca tcttcaactt cgaggccgtt aatcacaatg tcagcgccta cttcttttgc
      541 aagggcaagt ttgtcattgt tgatatcgac tgcgataaca tgagcattga atactttttt
      601 agcgtattga acagcgaggt taccaagtcc accagcaccg taaagaacaa cccattggcc
      661 tggttcaact tttgcttctt tgatagcttt ataggttgtt actccagcac atgtgataga
      721 agaagcttgg gctggatcaa gtccgtcagg aactttgaca gcatagtcag cagttacgat
      781 acattgttca gccataccac cgtctactga gtagccagca tttttcactg tacggcaaag
      841 ggtttcgcga ccagttgtac agtattcgca agtgccacat ccttcaaaga accaagcaac
      901 gctgacgcgg tcaccgactt taaggctttt cacatctgga gcaatctctt taacgatacc
      961 gataccttcg tgcccaagaa cacgtcctgg gacttgacca aagtcaccat gagcaacgtg
     1021 gaggtcggtg tggcaaacac cacagtattc aacttctaca agtgcttccc cagtttcaag
     1081 tggacggagt actttttctt caatagcaac accagtgctt tctggattta caacaacagc
     1141 tttcatagct atcctccttg atattgaccg agaacaggga caacgggact ggattgattt
     1201 tttgtcaaca gagtcgagtg tgacgagctc tcttgtattt atatgtgaag tatatcacaa
     1261 aagaaagcct tttccaaggt tttggagaca aaaagtagaa caatcgatta actggttgat
     1321 gagactgtga aaagagcaca aagaccagct tgcaagctgg tcatactctt cgaaaatctc
     1381 ttcaaaccac gtcagcttca tctacaacct caaagcagtg ctttgagcaa cctacggcta
     1441 gcttcctagt ttgctctttg attctcattg agtatcagta taggttataa gaataagtct
     1501 tgtagggttt tggcaacccc atcttggtcg ttggtaaggg aaatttgctc atctgcataa
     1561 gggagtagct ctggattggc atttttcatg gcataaccct tcccagcaaa agcgagcatt
     1621 tcggtatcat tgtgttcatc tccaaaggca atcaaatctt ttttgtcacg attcattatc
     1681 ttgagcaagt agtccaaagc aaaggccttg ttgacacctt ttggggtaca ttcaaggata
     1741 ttgagcggac ctccccaggt attgatagaa agttgatgct ggtagaaggc gttcatttct
     1801 tttgccaagg catatttgtc actggctctg gtctgcaaga ggatacagtt agggtccttg
     1861 gtcaccaatt caggctggaa ttgatcttca ggctggaaag cttctacacc aaatagtttg
     1921 ggattggcaa tttcttcatt gggatttgta atgtagaatt ttttacgata ttctccagcg
     1981 ataaaatcgg cttgaatgtc ctctgaacgt tgaaccatat ctagcagata ttttttgtct
     2041 acagtcaaac acttttcaaa atcccaaact tggtctggta aatgagtaag ggatccgttg
     2101 aagttaatca taggagtgtc taagcccagt tcacggtaaa aatcttttga catacggtaa
     2161 gggcgacctg tcgtaataat aacctgatgg cctttttcag caactttttt gatggttctt
     2221 ttggtaaagt cagaaatttg actgtctgag ttgagcaggg ttccatccag gtcaactgca
     2281 ataatttttt tcgtcatatg gacctttcta gtgtgttttc agataagatg tcttctatta
     2341 taacagaaag caggcagaaa agcagattcc aaacaaaaaa tgaaattgga ttaatttctt
     2401 aaacaaatca aacaaagaca ttgaaaaagt gaatgataaa tgatataatt ctattattgt
     2461 tcgtaaaaat taaaaggaga ttgatgatgg acaaattatt taaactaaaa gagaacggta
     2521 cagacgttcg tacagaggtt ctcgctggtt taacaacttt ctttgcaatg agctatattc
     2581 tctttgtaaa cccacaaata ctttcacaaa caggaatgcc tgctcagggc gtcttcctag
     2641 cgacgattat tggtgcagta gcgggtacct tgatgatggc tttttatgct aacttacctt
     2701 atgcccaagc gccaggtatg ggactcaatg ccttctttac ctttacagtt gtattcgggc
     2761 ttggttattc ttggcaagaa gccctagcta tggtcttcat ctgtgggatt atttcattga
     2821 ttattacctt gacaaatgtt cgtaaaatga tcattgaatc gattcccaat gctcttcgct
     2881 cagctatttc agctggtatc ggtgtcttcc ttgcctatgt agggattaag aatgctggac
     2941 ttttgaaatt cacgattgat ccaggcaact atactgttgt aggagaaggg gctgacaaag
     3001 ctcaagcaac gattgcagca aactcttcag cagttccagg attggtcagc tttaataatc
     3061 cagctgtttt agtggctctt gcaggacttg ccattactat cttctttgtc atcaaaggga
     3121 ttaaaggggg aattattctc tctatcttga caacaactgt tcttgctatt gcagttggtt
     3181 tggttgattt gtctagtatc gattttgcta ataaccatgt tggtgcagct tttgaagatt
     3241 tgaagacaat ctttggtgca gctcttggtt cagaaggatt gggagctttg gtttcagata
     3301 cagctcgctt gcctgaaact ctgatggcca ttcttgcctt ctcattgaca gatatttttg
     3361 acacaattgg taccttgatc ggtacagatg aaaaagttgg tattgtagcg acaaatggtg
     3421 aaaatcacca atcagccaaa ttggataagg ctctttactc tgatttgatt ggaacgacag
     3481 tcggtgccat tgcaggtact tcaaacgtaa cgacttatgt tgagtctgct gctggtatcg
     3541 gtgcaggtgg acgtactggt ttgacagcct tggttgtagc tatctgtttt gcgatttcaa
     3601 gcttctttag cccacttcta gcgatcgtac caacagcggc tacagctcca atcttgatta
     3661 tcgttgggat tatgatgctt ggtagcttga aaaatatcca ttgggatgat atgtctgaag
     3721 cagttcctgc cttcttcaca tctatcttta tgggattcag ctactctatc actcaaggga
     3781 ttgcagttgg tttcttgact tacactttga ctaagcttgt caaaggtcaa gttaaagatg
     3841 ttcatgccat gatttggatt ttggatgcct tgtttatcct taactacatc agcatggcct
     3901 tataatagaa tgacccaggg ggatttcccc ccttttttaa tacaaaggag ataggtgatg
     3961 aaagagaaaa atatgtggaa agaattgttg aatcgtgcag gctggatttt ggtcttttta
     4021 cttgccgtcc ttttatatca ggttccccta gtggttacct ctattttgac tttaaaagaa
     4081 gtagccctgc tacagtcagg gctgatagtt gctggccttt caattgtggt tctggctcta
     4141 tttattatgg gagctcgtaa aaccaagtta gctagtttta atttttcttt ttttagagct
     4201 aaagatttgg cacgtttggg cttgagttat ttagttattg tcgggtcaaa tatacttggt
     4261 tctatcttgt tgcaactgtc aaatgagacg acaacagcta accagtctca gattaacgat
     4321 atggttcaaa atagttcgtt gatttccagt ttcttcttgc tagccttgct tgctccaatt
     4381 tgtgaggaaa tcttgtgccg tgggattgtt cctaaaaaga ttttccgagg caaggagaac
     4441 ttgggatttg tagtcggtac gattgtgttt gctttattgc atcaaccaag taatttacct
     4501 tctttattga tttatggagg tatgtcgaca gttctatctt ggacggccta caagacccaa
     4561 cgtttggaaa tgtcgatctt gcttcacatg attgttaatg ggattgcttt ctgtttgttg
     4621 gctcttgtgg tgattatgag tcggacatta ggaatttctg tgtaaaagtt tttatgtagg
     4681 aaccgacctc tttctactag ggaaagatga atgcaatcgt gtccatcttt ttctttttat
     4741 ggtaaaatag aaaaataata tgatgaaaat ccttgaggga gtgaccgata tgtcaagtaa
     4801 agccaatcat gcaaagacag ttatttgcgg aattatcaat gtaaccccag actccttttc
     4861 ggacggtggt aaattttttg ctcttgagca ggcactccag caggctcgta aattgatagc
     4921 agaaggagcc agtatgctcg atatcggcgg agaatcgact cggccgggca gtagctatgt
     4981 tgagatagaa gaggaaatcc agcgtgttgt tccagtgatc aaagcgattc gcaaggaaag
     5041 tgatgtcctc atctctattg atacttggaa gagtcaagta gcagaggctg ctttggctgc
     5101 tggtgccgat ctagtcaatg atatcactgg tcttatgggt gatgagaaaa tggctcatgt
     5161 ggtagctgaa gcgagagcgc aagtggtcat catgtttaat ccagttatgg cgcgacctca
     5221 gcaccctagc tcgctcatct tccctcattt tggttttggt caagctttta cagaggaaga
     5281 gttagctgac tttgaaacat tgccaatcga agacttgatg gtggctttct ttgaacgagc
     5341 actagcgaga gcggcagaag ctggtattgc accagaaaat atcctgttgg atccaggaat
     5401 tggctttggt ctgaccaaga aagaaaatct cctcctttta cgggatctgg ataaactaca
     5461 tcagaagggc tatccaatct ttctcggagt gtcgcgcaag cgatttgtca tcaatatcct
     5521 tgaagaaagt gggtttgaag tcaatcctga gacagagctt ggtttccgaa atcgggacac
     5581 ggcttcggct catgtaacta gtatcgctgc gagacagggt gtagaagtgg tgcgcgtgca
     5641 tgacgtagct agtcacagga tggcagttga aattgcatct gccattcgtc tggctgatga
     5701 agcggaaaat ttagatttaa agcaatataa ataagatgaa agaaattgaa aacaatcagt
     5761 ggattgctaa ctaccggacg gatcaaccgc attttggctt ggaacgaatg gtggaactgt
     5821 tagctttgcg tggcaatccc catctcaaac tcaaggtcct ccatatcgga gggactaacg
     5881 gcaagggctc gactattgct tttttgaaaa agatgctaga aaagctaggg ctgagagttg
     5941 gcgtgtttag ctcgccctat ctcattcatt acacagacca gattagcatc aatggggaat
     6001 cgatctcaga agcgaggcta gaagctctca tggcagacta tcagtctttg ctggagggag
     6061 aagcggtcgc caatttacag ggcacaaccg agtttgagat tatcacagcc ctggcctatg
     6121 actactttgc ctcagagcaa gtagatgtgg ccatcatgga agttggcatg ggtggacttt
     6181 tggatagtac caatgtctgt cagcccattt tgacaggaat tacaactatt ggcttggatc
     6241 atgtggccct acttggtgac accttggagg ccatagcaga gcagaaggca ggtattatca
     6301 aacaagggat gcccttggta acagggcgta ttgctccaga agccttgact gtgattgacc
     6361 gcattgcgga agggaaagat tcgccgagac ttgcctacgg gacagattat caggttcgtc
     6421 atcaagaaag tgtggtgaca ggggaagtct ttgactatac aagtgctgtc agacaaggtc
     6481 gcttccagac tagcctgctt ggtttgtacc aaatagagaa tgctgggatg gccatagctt
     6541 tacttgatac tttttgtcaa gaagatggtc gagagctagc aagcaatgac tttcttggtc
     6601 aagccttgga agaaacaagt tggccagggc gtttggaaat cgtgtcaaga gatcccttga
     6661 tgattttgga tggagcccac aatccccatg ctatcaaggc cttgttggta accttgcaag
     6721 aacgttttgc ggattatcat aaggaaatcc tcttcacttg tatcaaaacc aaggccttgg
     6781 aggatatgtt ggacttgctg ggagccatgc cagataccga gcttactcta acacattttg
     6841 cggatagtcg ggcgacggat gaaagcgtgc tgaaagaggc agctaagtct agaaatctca
     6901 gctaccaaga ttggcatgat tttctagagc agaatttgac agataaaaaa gaagagaaac
     6961 aaacagttag gattgtcaca ggttccttgt atttcttgag ccaagtgagg gcctatctga
     7021 tggagaggaa gaacgagaat ggatacacaa aagattgaag cagctgtaaa aatgattatc
     7081 gaggctgtag gagaggacgc taatcgcgag ggtttgcagg aaacacctgc tcgtgtagcc
     7141 cgtatgtatc aagagatttt ttcaggtctt ggtcaaacag cagaggaaca tttgtcaaaa
     7201 tcctttgaaa ttattgacga taatatggtg gtagaaaagg atatcttttt ccataccatg
     7261 tgtgaacacc acttcttgcc attttatggt agagcgcaca ttgcctacat tccagatggt
     7321 cgtgtggcag gcttgtctaa gctagcccgt acggttgaag tttattcgaa aaaaccacaa
     7381 attcaagaac gtttgaatat cgaagtggcc gatgccttga tggactatct aggtgctaaa
     7441 ggagcctttg ttatcattga ggcggaacat atgtgtatga gtatgcgtgg tgttagaaaa
     7501 ccaggcactg caaccttgac gacagtagct cgtggtctat ttgaaacaga taaggacctc
     7561 cgcgaccaag cttatcgttt aatggggcta taaaaagaat ccgtttcaag cggatttttc
     7621 tagaaaggaa tcattatgga tcaactgcag attaaggatt tggaaatgtt tgcctatcat
     7681 ggtctttttc ctagtgagaa agaattgggg cagaaatttg tcgtttcagc catcctatcc
     7741 tatgatatga ccaaggcagc tacagacttg gatttaacag cctctgtcca ttacggagaa
     7801 ttgtgtcagc agtggacgac ttggtttcag gaaacgagtg aagatttgat tgaaacggta
     7861 gcctataaac tggtggaacg tacctttgag tcttatcctc ttgtccaaga aatgaagttg
     7921 gaactgaaaa aaccttgggc accggtgcat ttgtcactag atacttgctc ggtaaccatt
     7981 catcgccgca agcaacgagc ctttatcgcc ctaggaagca atatgggaga taagcaagca
     8041 aacttgaagc aagccattga caaactgcga gctcgtggca tccatattct caaagagtcc
     8101 agtgtcttag cgacggagcc ttggggtgga gtggagcagg atagttttgc caatcaagtg
     8161 gttgaggtgg aaacctggct accagcacaa gacttgttag aaaccttgtt agccattgag
     8221 tcagagctgg gacgggtgag agaagtgcat tggggacctc gtttgattga tttggacttg
     8281 ctctttgtgg aggaccagat cctttataca gacgacctca tattgcctca tccctacata
     8341 gcggaacgcc tttttgtcct tgagtcctta caggaaattg cgcctcattt tatccatccg
     8401 atattaaaac aaccgatccg caacttgtat gatgctttga aaaaatagaa aaactctagt
     8461 tttcagtcac ttgcaactga aggctagagt ttttatactc ttcgaaaatc tcttcaaacc
     8521 acgtcagcgt cgccttaccg tactcaagta cagcttgcgg ctagcttcct agtttgctct
     8581 ttgattttca ttgagtatta aaataggtca ttttcttctg ggaggaggat agtttctcta
     8641 ccgtccatgt ctaaaaccag tactcttggg ggataacgag ggtcgaaagg atggttaaag
     8701 tcaaaatcaa tggctgtagg gaggtgttga cttgaaaagt ggaaggtaat ctttccttgg
     8761 ttattaagca attgaaactc gagttcttct tccaattcaa agacattttt taagaaatgg
     8821 tcgataatat accaaaaaga gtcaatgatg tcatcaggca agctggtaac aatgccaaaa
     8881 ctagcagacc gcatgtgagt attggtaaaa gccatatctc tgtccccttt cttttccctt
     8941 atcatacagc aaataggatt aaaaatcaag aaaaggtgat tttttgaaaa ggattttaac
     9001 tacagggaaa aagaaggaaa aaaattccca aaaatctacc gaagttaata ggtaaattcc
     9061 caaattaact tgattatata actttcagtt actttgagaa gttaccgaaa aatatttttc
     9121 atatctattg acttttaggg gtgaaatttg gtatgatagt aggcggtatt gtttacccca
     9181 tttgaaaggc cccggaacct tccaaatact tttcgatggg aaggaacacc catcaccgta
     9241 aacaaaaatc gaactatata taggagaaat catgaacaaa acaacattta tggctaaacc
     9301 aggccaagtt gaacgtaaat ggtacgtagt tgacgcaact gatgtaccac ttggacgtct
     9361 ttctgcagta gttgctagcg tacttcgcgg aaaaaacaaa ccaacattta caccacacac
     9421 tgatacaggt gacttcgtga ttgttatcaa tgctgaaaaa gttaaattga ctggtaaaaa
     9481 agcaactgat aaaatctact acactcactc aaaccaccca ggtggattga aacaaatctc
     9541 tgcaggtgaa cttcgttcta aaaatgcagt acgtttgatt gagaaatcag ttaaaggtat
     9601 gcttccacac aatacacttg gacgcgctca aggtatgaag ttgaaagtat ttgttggagc
     9661 tgagcacact cacgctgcac aacaaccaga agttcttgac atttcaggac ttatctaagg
     9721 aaaggaacaa taaagtatgt cacaagcaca atatgcaggt actggacgtc gtaaaaacgc
     9781 tgttgcacgc gttcgccttg ttccaggaac tggtaaaatc actgttaaca aaaaagatgt
     9841 tgaagagtac atcccacacg ctgaccttcg tcttgtcatc aaccaaccat tcgcagttac
     9901 ttcaactgta ggttcatacg acgttttcgt taacgttgta ggtggtggat acgctggtca
     9961 atcaggagct atccgtcacg gtatcgctcg tgcccttctt caagtagacc cagacttccg
    10021 cgattcattg aaacgcgcag gacttcttac acgtgactca cgtaaagttg aacgtaagaa
    10081 accaggtctt aagaaagctc gtaaagcatc acaatttagt aaacgttaat tcgaaagaat
    10141 tactatactt atacagagca cctttcgggg tgttcttttt tatactttct tactaaattg
    10201 gtgcaattga cacagttgtt gcgactttag tcgcttacaa atgtggctgc aacctgacaa
    10261 ggtcagttgc ctcaaaacgt taatcaatac aattatatca acgtttcaaa gcactcaaga
    10321 gtttacctca tgggtgcttt ttttatgttt tttgaaaaag ttcacctcaa agtttacctt
    10381 attttcacct tattgtttta gagactgtaa ggcaaattca ccgacggcca tagggactac
    10441 attagaagta ttgacataaa tctgtgttgt acctgtgtcg ctatgtatta gagcttcaga
    10501 aatggcttct aagctcattc ctgcttgttt agcgagcgtt gctccggtat gacgtagttt
    10561 gtgtggcgta gcgtgtgtaa gctctgggtg tcgttttctg atagttttca tcttattatt
    10621 gagatagtca gaatgtaaag gtttattgat attgcctttg gtatctatgt aagtaaagat
    10681 gaattgttct ggattactga tgataccaaa ctttgccagt tcatattttt gttgtttttt
    10741 ccatgaagtc agaagttgaa gtaagtcatt agaaatagag aaaatgggaa atgtttccac
    10801 aataaaacgc atattatcag atggttaatg cgttttatat ttgggtttga ggcttataaa
    10861 ataggataag cgtgctgaaa acttagatat gacaaacaaa ataaaatttt taaaagctac
    10921 atagaaacat ggtataatgt atctaaagga ggtagcatat gtccttagat atagataaag
    10981 aaaagatgac aatcatggga atagcttttg aaaaccgatc cgtttttaag agtgtttggt
    11041 atgctttaag tacaaatatg attgaaggat ggcgacctac ggttagtgat gttgaaaaat
    11101 tacgagatga agctcttgct ctggggatga cttaatgaaa cgcaactgtt atgagtctta
    11161 tgactatgtt gatcctgata atttatatac cgatccgggt tcttcagttc taagaaataa
    11221 gcaggaagga aaaaagcacg tgagcttgaa tatcgtatga ttgctagtaa gagtttgaaa
    11281 ttatttatca atcctatctt agttaatagt ttaaaagtag tttgtttcac aactgcataa
    11341 gcttagaaaa gttgaaaagt gataactctt taataaactc ttggtttgtt aaaagatatt
    11401 ttgtccactg cattttttca attgactatt atttgtcata gatataacag atagaacatt
    11461 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
    11521 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    11581 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    11641 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    11701 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    11761 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtatttcggt
    11821 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    11881 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    11941 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    12001 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    12061 atacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    12121 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    12181 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    12241 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    12301 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    12361 gaagaagctt atcctcaaat cgcaaaacga ttggggttaa atgtagaact agaagaacct
    12421 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    12481 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    12541 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    12601 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    12661 ttttcagggg atactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    12721 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    12781 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    12841 cgattacata gttctagaag tccttttaat agtaaagaac cttggttttt ttcagaaaca
    12901 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ttatctatat
    12961 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    13021 tatccagaga atgatgagag ctataatgtt ccaaatcaat acttttttgg aacagaactg
    13081 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    13141 tggttccctg aaggtgaatg gtatgacttt ttttcagaga aaaaatacac aggtggtgtg
    13201 aagttaagtg tttatagaga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    13261 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaagt tgtagattgg
    13321 tatgtattcc caggaaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    13381 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    13441 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    13501 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    13561 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    13621 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    13681 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    13741 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    13801 tattcgttat cactggtcac attgaaaatg tgaaatgagc acctacaaca tagactttac
    13861 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    13921 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    13981 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    14041 tgcccatcac gaccaatgag aaacttagcg aaattccatt cgattcgttt tcctagtggg
    14101 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    14161 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    14221 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    14281 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    14341 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    14401 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    14461 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    14521 aagaataagc cctcaatatg atagaaaccg tttacaaata actttaaaaa tggtatgatt
    14581 taattaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    14641 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    14701 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    14761 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    14821 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagtccgt
    14881 ggacagggag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    14941 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccctgaga
    15001 aattaagggc agcggttcac cgtatggttc ctattgaagc taagaaaaag tataaactgc
    15061 gtttcaagat taaaacagat cataaagtcg ggattgccaa agttcgtatc attgaggaaa
    15121 gtgataagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    15181 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    15241 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagacc
    15301 agccttctga ggactatcaa acagataaac agcttgagga aaagattgat ttaccaattg
    15361 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    15421 cttcagtcaa aaatggaatt ttagaacctc ttaaggaagg gacaaccaat gtcattgtca
    15481 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggatg
    15541 catacacaga ccgtttggat gactggaatg gcatcatcgc tgggaatcaa tactatgatt
    15601 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    15661 tatccagtat ttcaagtcag gcggaccgca tctatttgtg ggaaaaattt tcaaattata
    15721 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    15781 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    15841 tggaatggat gcataaacat gtctacaata gtgaaaagag cattattggg aactggtggg
    15901 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    15961 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    16021 aacatttccg aaagacgact gataacccat tcaaggctct aggtggaaac ttagttgata
    16081 tgggaagggt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    16141 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    16201 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    16261 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    16321 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    16381 gagagttgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    16441 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    16501 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    16561 tctttaataa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    16621 caggagtcgc aagtgttcca agaacaagtt acctatctgc ctttaacaag atggataaaa
    16681 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    16741 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    16801 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    16861 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    16921 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    16981 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    17041 taaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    17101 caactacaat tgaccagaga aaactggaat caggtaatcc atataaagtc tatgtcaatg
    17161 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    17221 tagaatcgtt cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    17281 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    17341 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    17401 atggctatat gctcattcct aacgtggatc gtgccacctt caatcaaatg ataaaagagt
    17461 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gctaaacaag
    17521 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    17581 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    17641 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    17701 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    17761 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    17821 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    17881 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    17941 atcttcggat ttttctttta aaaaaggata agttgatact tatccttttt tacttcatta
    18001 ttatgtgact atagcgtttt gaaactagaa tagaacgtta taactgctaa aagatttcta
    18061 taaattcatt tgattttcct aatcaatttg ttcgtatcct atttcactcc actatataag
    18121 tccgtctcgc tccgtgaggt gcgcgtcgaa ggttatacca aaaaaactcc aaacgcgata
    18181 caataaaggt gttcactcca attgtaaagc gaaaggagaa aaaatatggc acaaaagact
    18241 catagtttat catacacaaa gtggatgtgt tctatcatat tgtgttcacc cctaagtata
    18301 gacgaaaagt catctataat caatatagaa gtagtttagg cgaaatattt catcgcttgt
    18361 agttataaag gtgttgaaat gatcgagggt cacttaatgc cagaccatgt acacatgtta
    18421 gtcagtattc cactaaggct aagtgtttcg agtttcatgg gttatttaaa aggcaaaagt
    18481 gcactcatga tgtttgacaa acacgccaat ctcaagtata agtttgggaa tcggcatttc
    18541 tgggcggaag gttattatgt aagtacagta gggcttaata aagccacaat taagaaatat
    18601 agtcaagatt aaagaaatta tccagtggat gatttcttca cgagtatgaa aatttgagaa
    18661 cgagtaaagc atgatatata gtaaaatgaa ataagaacag gacaaaatcg atcaggacag
    18721 tcaaatcgat ttctaacaat gttttagaag cagaggtgta ctattccagt ttcaatctac
    18781 tatagcacta gataaattga gtgtaaaaga atatgaggat ccctttaggg atagtggtaa
    18841 gtaataccaa agtctcttaa agaggcaagt gacgagtcaa gagcaataag gcttgaacaa
    18901 cgtaaaagcc agcgtcttta gacgctggct ggtaatttgg gcttatagct ctgggataaa
    18961 ccacccgttt gacgggtggt tatgatttta tctgagtgta acatactgtt gggcaatctt
    19021 gctgatgcgg tcaaagttgc cttgggaagc gagtttattg agttcgccac caattccaac
    19081 ggcgtctgca ccagcagcga accattgagg gatgttgttt agaccgactc ctccggttac
    19141 cattacggaa acttgtggga tcggtgcctt gactgcagag atatatgctg gactgagagt
    19201 actacctggg aagagtttga tgatttcact accggcttca agtgcagtcg tgatctctgt
    19261 gagggtaata cagcctggaa tgtacggtgt gctgtagaga ttgcacattt tcgcagtttc
    19321 agcatggaaa gatggagaaa caacgtaatt tgctccggct agaatggcat ctctagcggt
    19381 tacggcatca agcacagtac ctgcaccgat acaaacactc tgatcgtcct gatacaagtc
    19441 tacaagttcc ttgatgattt gtcctgcata ctgattggta taggcgattt caatagcttt
    19501 gataccgccc ttgatacaag caatcgaggc ttgtagtcct tcttcctttg tatttcctcg
    19561 aatgacagcg acaattttct gtttttttag ttcaataatt gtatctgatt tggtcatgta
    19621 attctcctaa cgaatgatat cttgtgcatt tgccagtaaa ttttcaatac tagttgcgga
    19681 agtggagaga tggtctcctg gaagagtgca tttgagagtt gcgctcgcaa ctgcaaagtc
    19741 aatggtagtt tttagggagg aatgatggag tagttggtaa agggcaccag atataaaggc
    19801 atccccgcta ccaattcgtt gatagactgc agtttttagt tggacagact cttcaaatcg
    19861 ttcttctaga gcataggctt gatagacatt tttgtcttgc tcatcactag agcggagggt
    19921 atggaaaatg gccttgaaac cataggcttc ttttaaaagt cgcatgcgat tttccacctc
    19981 ttctaggcta gcactgtctc ttggaaacat ctctagattt tggtcatcaa tcatgagagg
    20041 atcaataccg aagcaatagt cagtaaaacg tgcaaactta gaaaattcat acttggcttc
    20101 taggactgaa atcatctttg ttctcagatt gagatccatt gaaacgacaa ttcctcggcg
    20161 cttggcttct tccaagagta ggagaaggat cgtacggacc tcttgaccga tagctacggt
    20221 gattccacta aaatgaaaat ggctaatccc ctgaaagaga gaatccatat ctagcatgtt
    20281 tggccgaatc tggctgatac tcgtatgctt acgatcgtag aaaacttcac tttgacgaca
    20341 accaaagccg ttctccaaat agtagaggcc gattcgatcg ccaagccgac agattgaact
    20401 ggtatcgatt tggtgctgtt tcaagaatgt gagaaaacga tctccaatct cgttggcagg
    20461 gagtgcggta aagactttcg ttgagatacc cagggcttgc aaattacaag cgatgttaat
    20521 ttctgatccg ccaaaataag tcgaactggc aacatgatcg ccgatactgg tggcatctaa
    20581 tggtgagatt cgaattaatg gttcgccaaa cagtaatatt ttcgtcatcc attagttcct
    20641 ttctggttta gaatagcttt acttggctaa tacttctttc aaataagcag cgatttcatc
    20701 atcttggcag ttttcaaaga agtattcttg gaagtatttg ccagagatgg tgtctttgag
    20761 gaagtcttgg tcgattgttt taaggatggt catcaaatca ttgtgggtga tttgtttcac
    20821 ctcgtttaag atacgagcgt tgcgttgttc agggattaca cgttctcttg ggtagccacc
    20881 gcccatttct tcagcaaata agcgttcaaa catcaatttg agggtcagtt ctgcccccca
    20941 gccaaatcct ttggcataag ggatagacaa ggcgttacca ccattgattt gagaataaag
    21001 gtaagcgtca gttgggtcca ctgctagacc acagacaaca ccagggaagc tgtttaaagc
    21061 aagcatagcc cctacacccg taccacagcc ggtaacaaca aagtcaactg cctttgtatt
    21121 taaaaggatg gcagccatta gtccgttctg cacataagtt aattgacttt ctccttcttc
    21181 tccacgcata ccatagttaa ataattggta gtctttttta tctgtcgctt cttttagact
    21241 atcgtaaata atgtgattct tgctagcttg actattttca ttgattaatg cgattttcat
    21301 aagatcttct ttctattttt actcaggttg ttttccgatg taggctaaga taccgccatc
    21361 tacatatagg atgtggccat tgacaaaatt gctggcatca ctagcgagaa agacagcagg
    21421 gcccatcaaa tcttcaggat ttccccaacg tgcagcaggt gtttttgcaa tgatgaactg
    21481 gtcaaatggg tggcgagaac catcttcttg caactcacga agaggtgctg tttgaggagt
    21541 ggcaatataa cctggtccaa ttccgttaca ttggatattg gctccaccgt attcagacgc
    21601 aatgttgcgg gtcaacattt tcaagccccc tttagcagca gcataagcgc taactgtttc
    21661 acgtcccagt tcgctcatca tcgaacaaat attgataatc tttccatgcc ctttctttat
    21721 catagaagga ataactgcct ttgaaacgat aaatggtgcg tttaagtcaa tatcgatgac
    21781 cttacggaaa tcagcggcgc tcatttcgca cattggaatt cggcggataa taccagcgtt
    21841 attaacgagg atgtcaatga caccaacctc ttgttcgatt tgcttgacca tggcttggat
    21901 accgtcctcg tctgtcacgt cacagacata tccatgggct tcgatgccaa cttcacgata
    21961 agcttcaatc cctttattga ccagatcttg attgatatcg ttaaagacaa tagtagcgcc
    22021 ggcttcagcg taggatttgg caatagcaaa tccaattcca taagaagcgc cggtgatgag
    22081 agcaattttt ccttttaaag aaaactgctc aattgagaat gatgtatttg tcatttgata
    22141 cttcctttca aatttgttaa gacttctcta taa
//
LOCUS       DAVMCG010000030        21979 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVMCG010000030 DAVMCG010000000
VERSION     DAVMCG010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21979
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.031"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(141..1364)
                     /locus_tag="VYP66_001422"
     CDS             complement(141..1364)
                     /locus_tag="VYP66_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1850966.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1532..2854
                     /locus_tag="VYP66_001423"
     CDS             1532..2854
                     /locus_tag="VYP66_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1850967.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2856..4742
                     /locus_tag="VYP66_001424"
     CDS             2856..4742
                     /locus_tag="VYP66_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEV1850968.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4910..5254
                     /locus_tag="VYP66_001425"
     CDS             4910..5254
                     /locus_tag="VYP66_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1850969.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5264..6676
                     /gene="lacG"
                     /locus_tag="VYP66_001426"
     CDS             5264..6676
                     /gene="lacG"
                     /locus_tag="VYP66_001426"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1850970.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6746..8425
                     /locus_tag="VYP66_001427"
     CDS             6746..8425
                     /locus_tag="VYP66_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1850971.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8551..9990)
                     /locus_tag="VYP66_001428"
     CDS             complement(8551..9990)
                     /locus_tag="VYP66_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1850972.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(9994..11343)
                     /gene="trkA"
                     /locus_tag="VYP66_001429"
     CDS             complement(9994..11343)
                     /gene="trkA"
                     /locus_tag="VYP66_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1850973.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11532..12380
                     /locus_tag="VYP66_001430"
     CDS             11532..12380
                     /locus_tag="VYP66_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1850974.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12395..12943
                     /locus_tag="VYP66_001431"
     CDS             12395..12943
                     /locus_tag="VYP66_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1850975.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12950..13162
                     /locus_tag="VYP66_001432"
     CDS             12950..13162
                     /locus_tag="VYP66_001432"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850976.1"
                     /translation="MKIKEQTRKQVAGCSKQCFEVVDETDEVSNHTYGKAKLTWFEEI
                     FEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            13264..14946
                     /locus_tag="VYP66_001433"
     CDS             13264..14946
                     /locus_tag="VYP66_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850977.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            14931..15761
                     /locus_tag="VYP66_001434"
     CDS             14931..15761
                     /locus_tag="VYP66_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1850978.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            15954..16457
                     /locus_tag="VYP66_001435"
     CDS             15954..16457
                     /locus_tag="VYP66_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1850979.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16511..16745
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            16910..17473
                     /locus_tag="VYP66_001436"
     CDS             16910..17473
                     /locus_tag="VYP66_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1850980.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17487..18113
                     /locus_tag="VYP66_001437"
     CDS             17487..18113
                     /locus_tag="VYP66_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1850981.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18141..18530
                     /locus_tag="VYP66_001438"
     CDS             18141..18530
                     /locus_tag="VYP66_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1850982.1"
                     /translation="MKVNIADLHLTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18535..18984
                     /locus_tag="VYP66_001439"
     CDS             18535..18984
                     /locus_tag="VYP66_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV1850983.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKKIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            19112..19699
                     /locus_tag="VYP66_001440"
     CDS             19112..19699
                     /locus_tag="VYP66_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1850984.1"
                     /translation="MKLEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVTPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            20089..21696
                     /locus_tag="VYP66_001441"
     CDS             20089..21696
                     /locus_tag="VYP66_001441"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1850985.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6543 a         3736 c         4838 g         6862 t
ORIGIN      
        1 agttatttta atataaatca ctcaacatag agagaaggcg gtttcctata tggaagtcgt
       61 cttgttttca tattgtctaa atacgagata tctactacag gttatagttg atttaaacag
      121 gtctatagat ttctaatata ttaaggtgaa ataatatctt gtaatacatt gctatgttct
      181 atgaaaaaag cgacgatagc taatgcacaa gctcctatac ttccacgatg tttgttgtaa
      241 ggtaaaattt caatttctat attacgagta aagggaacga agtggagctg gtcttggatt
      301 ttatccctga cttcatgagt gaaaggttga taattaagca attgactgtt gatatagatt
      361 ttatcagcag gattgatgag gaggagattt gcaatagaag tggctaataa attgactcct
      421 ttatcaattt gttgacgtaa agcggagtcg cctaaattat aagccgttaa aagggtgtct
      481 aaatgaatgt ctttttcagt ctttacaagg ctttttagta cagttagttg ggaattttta
      541 aataataatt gggcgtgttt gattaaccaa gcatccgaaa tatatgtttg taaacaacct
      601 ttttttccgc attcacaata ttgcccattc aattcgacaa tggtgtgtcc aatttctccg
      661 atataaggat ttttagaggc tcctattttt tcttttgtga aaaaggaagt gtaaatacct
      721 aatccagcgt gtaggaaaat aaagttatcg ggggtattgt gtggattaaa aaggtattgt
      781 cctatagcca tacaatcgat attatttttt acaataaaag gaaaattgaa tcttttaatt
      841 acatttaata aattaaaaga ttcccatatg gggttgtttg taatgatact tccggagtct
      901 ttgttataat gtccaggtat tgataagcca aatccaagta attttgtttc caaagggacg
      961 tactctatag ctgtttttat catattggta atggtggaat tgatttctga aataggataa
     1021 tcttcattca aaatttctgt ctcgaaaaga gttttccctt gtaagtcaca tagactgaga
     1081 aagataccta ggacgtttat ttcaatacct ccaacaacat acggaatatt atctgtgata
     1141 gaaatagttt ttctacgtct tccagatccg gaaaactcgc taaattcatc accagtttcg
     1201 tatatgaggg actgttcgct tagctctttt atgatgttag tcgttgttgc tggagtaagt
     1261 cctgtttcat taacaatatc tgtacgggat gttgctggat ttcgatatag aaactccagt
     1321 atagtggctc tattttgtaa aaaggctgat tgttttgtaa tcatttgttt cctcctttgg
     1381 tttattttat attaaacata agaaaaaatc aattaaaatt attattttat acaaagaaaa
     1441 aaatattgta aaaacaacaa aaaatatatt gacaacgctt tctgttagtg gtatatttaa
     1501 tttataaaaa ataaaaaaag gagttccggt gatgaacaat attttagcgt ttttagaaac
     1561 aaaagtcgct ccgtttggtg aaaaagttgg caaccaacgg catttgaaag ctattcgtga
     1621 aggatttatg atggcaatgc ctttgatttt agtcggatct ttatttctta ttctaatcag
     1681 ttggcctcaa gaggatttta caaattggct gaatagtgtt ggattgctaa gtatcttgac
     1741 aactatgaat cagtcaacag tagcgattat ctccttggtc gcttgtttcg gtattgccta
     1801 caggttgtcg gaaggatatg gtacagatgg tccgtcggca gggatcatag ccttatccag
     1861 ttttgtattg atggcacctc gtttttcgag tatggtttat gataaaaatg gggagcaggt
     1921 caagcagtta tttggcggcg caataccatt ttctagcctg aatgcatctt ctttgtttat
     1981 ggcgattact attggattgg ttacagcaga gatttatcgt atgtttatcc agcgcggaat
     2041 tacgataaaa atgccaagtg gtgtcccaga tgtggtaagt aaatcatttt cagctctttt
     2101 acctggcttt actacttttg ttttgtgggc tctggtctta aaaggtcttg aagcggcagg
     2161 agttgcagga ggtctcaacg gactcctagg tgcaattgtt ggaacaccgc ttaagttaat
     2221 tgcaggaacg cttccaggta tgattctatg tgttattgta aactcattct tttggttctg
     2281 tggagttaat gggggacaag ttttaaatgc ttttgtagat ccagtttggt tacaatttac
     2341 tacagaaaac caagaagctg tggctgcagg acaaacactc caacacatta ttacattacc
     2401 gtttaaagat ttatttgtat ttattggtgg cggtggagcg actattggtc ttgcgatttg
     2461 tctcttccta tttagtaaga gtcgtgcgaa taaaacatta ggtaagctag ctattatacc
     2521 gtctattttt aatatcaata cagctattct atttacgttt ccaacagttt taaatccgat
     2581 tatgctgatt ccgtttattg ctactcctac aatcaatgcc ttaattacct atgtatcaat
     2641 ggctgtagga ttagtaccct acacaacagg tgtaatcctt ccgtggacaa tgccaccgat
     2701 cataggaggc ttccttgcga caggagctag ttggcgagga gctctattac aagttgtttt
     2761 gattttggtt tctgtagcaa tttattatcc attcttcaaa attgcagata aacgcaatct
     2821 tgaaaaagaa aaagctactg ttggagggaa ataagatggt tatcagagta tttgatcagc
     2881 agaaaaatac ttattctagc tttgccttag aggaattaag ttactatata aatcgggtct
     2941 ttaagactga catagaactt gtcgaggaga aggaagcgga tatttttgta ggattagtca
     3001 ataaagagga tagaaaagac catgttctta tctcattaga caagggtaag gggagaattg
     3061 agtctaatac aattgtaggt ttacttattg gaatttaccg aatgtttcat gaatttgggg
     3121 ttgtgtatac tagaccaggg cgcggacatg actttgttcc agagttacga tttgaagatt
     3181 ttttagataa agagctatct atagatgaaa cagccagtta ctatcatagg ggagtatgta
     3241 tagagggagc agattcattt gaaaatatac tagatttcat tgattggcta cctaagattg
     3301 ggatgaacag ttttttcatt cagtttgaaa atccctattc ttttttgaaa cgttggtatg
     3361 aacatgagtt taatccatac ctaaataaag aaaaattctc aaatgaatta gtacaagaat
     3421 tgagtgatag gttggataaa gaattgcaaa aaagaggtct tattcatcat cgtgttggtc
     3481 atggatggac aggtgaggtt ttaggttact cttcaaaatt tggctgggaa tcaggtctta
     3541 gtatttcaga ggagaagaaa ccctatgtcg ctgaaataaa cgggaaacga gaattattta
     3601 atacggctcc gattttaacc agtctggatt tttcaaatcc agatgtggcg gataagatgg
     3661 tagaaattat caaggattat gccaagaaaa gacctgatgt taactactta catgtatggt
     3721 tgtcggatgc tcgtaataat atttgtgaat gcgaaaactg tagacaagaa ttggtttcgg
     3781 atcagtatat tcgtattctc aatcaattgg atagggcttt aacgagtgag ggattagata
     3841 caaagatttg ttttctgctt taccatgagt tgttatgggc gcctcagaaa gaaaaattag
     3901 ataatcctga acgctttacc atgatgtttg caccgattac aagaacattt gaaatgagtt
     3961 atgcagatgt agattttgac aattccatac ctacgcctaa accttatctg cgtaataaaa
     4021 ttatacttcc gaattctctt gaggaaaatt tatcttatct ttttgagtgg caaaaaacat
     4081 ttaaaggaga tagtttcgta tatgactatc ctttagggcg tgctcattat ggcgatttag
     4141 gctatatgaa aattagtcaa accatttaca gagatgtatc ttatctttct aacctacatt
     4201 tgaacggtta catttcgtgt caagaattac gtgccggatt ccctcataat tttcctaatt
     4261 atgttatggg ggaaatgctc tggaagaaga caagaagtta tgaagaattg attgaagaat
     4321 acttttctgc tttgtatggg tcaaattggc agtctgttgt tgaatattta gaaaaattat
     4381 ccagttattc ctcatgtgat tattttaatg caattggcag tcgtcaaaat gatgttttag
     4441 cgaatcatta ttatatagct tacaatctag ctgataattt tttgccaatt attgaggaaa
     4501 atatttctaa gttattaaat agtcaaaagg atgaatggaa acagctcagt tatcatcgtg
     4561 aatatgttgt taagatggcg aaggctttat atcttcaagc aaccggaaaa acaaggcaag
     4621 ctcaagatga atggagaaat gtgttgaatt atatccgtgg gcacgaattg ctatttcaat
     4681 ctaatttgga tgtttatcgt gtaattgaag tagcaaaaaa ttacgctggt ttccacttat
     4741 aaatcataag tatagaaaat gaaccaaggt attcagagaa gattgatcct aaatattatg
     4801 aaatttaagg atttttaaga tatttagggt cgactttcta tttatatcgt agcgaagtca
     4861 ttttaataat gatgtgtaaa agatggatca agattgagga ggaagaaaga tgaaatcaaa
     4921 agaagaaata aatatgcttg gttttacaat tgtcgcttac gcaggagatg caaggtcaga
     4981 tttgatggat gctttggcgt ttgcgagaga tggatatttt gaacaggcaa gagaattggt
     5041 tgagtctgca aacgactcaa tagtgtctgc ccatcgagaa cagactaatt tattagcgga
     5101 ggaggcatct ggagataatt ttgaagtgag ttttatcatg attcatggtc aagatacctt
     5161 gatgacaacg atgctattgt atgatcaggt caagtttttt attgatgaat atgaacgaat
     5221 tcgaaagatt gaagaacata ttggtttgca atgaggatta gtcatggaaa atttacaggt
     5281 taaagcctta ccgaaggagt ttttattagg agctgctacc gctgcttatc aagtagaggg
     5341 tgcaactagg gtagatggca aaggaacaaa tatgtgggat gtttatttgc aagaaaacag
     5401 tccgttctta ccagatccag ctagtgattt ttattatcgt tacgaagagg atataacttt
     5461 ggcggcagaa catggtttgc aggctttgcg tttatctatt tcttgggttc gtatatttcc
     5521 tgatatagat ggggagccta atatattagc tgttcgttat taccatagag tctttcagtc
     5581 ttgcttaaaa cataatgtga ttccgtttgt ttctttacat cattttgatt cgcctcagaa
     5641 aatgttagaa acaggggatt ggttgaatag agagaatatt gatcgtttca tacgatatgc
     5701 tcgcttttgt ttccaagaat ttacagaagt caagcattgg tttacaatca atgaactgat
     5761 gtctcttgct gcaggtcaat atataggagg tcagtttcct ccaaatcatc attttcaatt
     5821 atctgaagca attcaagcga atcataatat gttgttggcg catgctcttg cagtcctcga
     5881 atttcatcaa ttaggaattg agggagagat aggttgtatt catgctttaa agccaggcta
     5941 tcctattgat gggcaaaaag aaaatatttt ggcagctaaa cggtatgatg tttataataa
     6001 taaatttcta ttagatggaa cttttttggg ctactacagt gaggacacgc tttttcactt
     6061 gaatcaaata ttggaagcta ataattctag ctttattatt gaagatggtg atttagaaat
     6121 tatgaagaga gctgcagctc ttaatacgat gtttgggatg aattattatc gttcagaatt
     6181 tattcgtgaa tacaaaggtg aaaatagaca agaatttaat tcaacaggaa taaaaggaca
     6241 gtcttctttt aaattaaatg ctctaggtga atttgtaaaa aaacctggta ttccgacaac
     6301 agattgggat tggaatattt atcctcaagg gttatttgat atgttgcttc gtatcaaaga
     6361 agaatatcct caacatccgg tcatttattt aactgaaaat ggtacagccc ttaaagaagt
     6421 taagccagag ggcgagaatg atattattga tgacagtaag agaatccgtt atattgagca
     6481 acatttacac aaagttttag aggctcgaga tagaggagtc aatattcaag gctattttat
     6541 atggtctttg caagatcaat tttcttgggc gaatggctac aataagcgat atggtctttt
     6601 ctttgttgat tatgaaacac agaagagata tattaagaaa agtgctcttt gggtaaaagg
     6661 gctaaaacgg aattaaggtt agcgatttga ctgatgttta atatatttta actatgagct
     6721 taaatttttt acaggaggag tttttatgga taagttagtc gctgccattg aaaagcaaca
     6781 agggaaattt gaaaaaattt ctactaataa ttatatgata gctattaaag atggatttat
     6841 tgctactatg cctttaatta tgttttcaag ctttttgatg attattatta tgattcctaa
     6901 aaatttcgga gtagagttac cgagtccagc tattgcctgg atgaggaaag tgtatatgct
     6961 aaccatggga gttttgggta ttattgtttc agggacagtt gcaaagtcat tggctggaaa
     7021 tgttaataga aaaatgcctc ctggaaaggt aataaatgat acttctgcaa tgttggcggc
     7081 catatgtggc tatcttgtat taactgtaac gcttgtagtt gatgagaaaa cgggatctac
     7141 aagtttgtcg acaaactatt taggatctca aggattgata acttcgtttg tcagtgcctt
     7201 tattactgta aatgtttacc gattctgtat taagcgagac attactattc atttacctaa
     7261 ggaagttcct ggggctatat cacaagcttt tagagatatt tttccttttt cttttgtttt
     7321 acttattagt ggtttgttag atattgtatc tcggtttagt ttagatgttc cttttgccca
     7381 agtatttcaa caactattga ctcctatttt taagggggca gaatcatatc ctgctatgat
     7441 gttgatttgg tttatgtgtg ctttgctttg gtttgttgga attcatggac catctattgt
     7501 cttacctgct gttacagctt tacaactgag caatatggaa gagaatgctc aacttcttgc
     7561 aaatgggcag ttcccttatc attctttaac acctaatttc gggaattata tcgctgctat
     7621 tggaggaacg ggggctacct ttgttgtacc atttattttg attttcttta tgcggtctaa
     7681 acaattaaaa tcggtaggta aagctacaat tactcctgtt ttatttgcgg taaatgaacc
     7741 tcttctattt ggtatgcctg ttattttgaa tccctatctt tttgtccctt ttttgatgac
     7801 tccaccagtg aatgtatttc taggaaaggt atttattgat ttctttggaa tgaatggatt
     7861 ttatatccag ttaccttggg cctttcctgg tcccttggga ttgttaattg gaacgaattt
     7921 tcaacttatc tcctttgtat ttttatcttt gatgttagtt gtcgacatat tgatttattt
     7981 gccattctgt agagcgtatg atagacagtt actggtgaaa gaagatattg caagctcaaa
     8041 tgatattatt ttagaggagg atacaagtga aataatgcct ggtgagatag atgtaataaa
     8101 aagtaaggag ttgaaagtac tggttctttg tgcagggtct ggaacaagtg cgcaattagc
     8161 caatgcaatt aacgagggcg ctcaattagc agaagttaga gtgattgcga attcaggagc
     8221 gtacggagct cattatgata ttatgggtgt ttatgattta attattctgg ccccacaagt
     8281 tcggagttat tatagagaga tgaaggtgga tgcagaaaga ttagatattc agatagttgc
     8341 taccagagga atggaatata ttcatttaac aaagagtcca agtaaagcct tacaatttgt
     8401 attggagcat taccaagctg tgtagtaagt ttttccatct tttatttgag taaagatttt
     8461 gcttacagat aggcttggat ttaaaaacgt tccccctttt ttaatataag aatccctctt
     8521 tcacaattgt aaaaagaggg attttgtatt ttatctctta gaccaagttc tcttcataaa
     8581 gagaaggagg attgggtaaa tctccaagcg ccctgcaatc attgcaaagg ataggagaat
     8641 ttttgagatg ggactaaaga ttgagaaact agaagtggtt cctagaatag gcccgatatt
     8701 attgaaacag ctaaagacag cgctggtcac gaccagaaaa tcattgctat ctaggctgac
     8761 aataaagata agcgctagca aaatcatagc atagatgaca aagtacttga gaatcttatg
     8821 ctgggtatct ttgtcaatca ccgttttatt aacatggagg gtcaaaacac ggtggggcga
     8881 taggattgac aaaatttggt ttttggcaat ttttgaaagg atgaggcctc gaataatctt
     8941 gagtccacct gcagttgatc cagcagagcc accgattgcc atgaggaaaa ggaggataaa
     9001 ctgggagaag aggggccagt tggtaatatc tccatatcca aaaccagttg ttgtaatgat
     9061 gttggaaacc tggaagaagg tcatttcaaa gctctttgaa aaccctgggt agaggtagag
     9121 ggtgttgagg ctaatcaagc ctgtagaaac cagtacaatg accaagtaag ccctaagctc
     9181 ttcatctcca aagaaggcct tgatgcgacg gagcatgagg tagtagtaga ggttgaaatt
     9241 tactccaaaa accagaactc cgatactgac cagataggta atcagtgagc tgccatagtg
     9301 ggcaattccg tcgttataga cggtaaagcc tccagttccc gctgtcccca tagcaataac
     9361 aaaactatcg tagagaggca taccggctag ataatagatg atgacaaaga gggagaagag
     9421 agctagataa aggagataga gaatctgggc agtgtttttt agtttggata caaccttgcc
     9481 aaaaacagga cctggaacct cagccttcat cacctctagg tggctatttt tggcattgtc
     9541 cataatagca agtgcaaaaa caagcactcc catccctcca atcaagtggg taaaacttcg
     9601 ccagaagagg agggaacggc tgagaaccga aacgtcgttc aaaatacttg ctccagtagt
     9661 tgtaaatcca gaactaattt caaaaaaggc atcaataagg ctggggattt gcccagaaaa
     9721 gacaaagggg agaccaccaa agaaagacca aaggatccaa cagagggcaa cgatcaagac
     9781 tccctccttg gcataaatcc gttgattttt tggcttctgt aaactccctg aaccgcctaa
     9841 caatacgaga atccctatgg tcgaaaagag ggctgtaaag acttggctcg attcacggta
     9901 atagacagca atcgcaacag gaaccaaaag aagaacagct tcaatcaaaa gtaattttga
     9961 aaggaggtaa cgaatcatac ttttattcat ttcttacctc gcgatcaagt cataaatctt
    10021 ggtgatgttt ggcaacaagg ttgttactag gagcttgtct ccaacttcca acatatcctc
    10081 cccagttggg aaaatagtct tgccctttcg aataatggct gcaataagaa cccctttttt
    10141 taatttcagt tgagaaagag gtttggcagt cattttattg gcttccttga tatggaattg
    10201 cagggtttcg atttggccat tggctagatg gtgcatggct tgaaggtctg aatactgggc
    10261 attaactcga ccacgaataa agtgcataat cgtatctaca gcgatgcttt taggtgtgat
    10321 gatacttgaa aaatcaggcg cattgataat ctcgaggaga ctggtacgat tgaccttagt
    10381 aatatttttc tgtacaccta ccctgtcaag gaacatagat gtaatcagat tttcctcatc
    10441 gacacctgtt agagtcgcaa cggcatcata gtgttgagca ctttcttcca gcaggatatc
    10501 ttttgcggtt ccatctcctt gaacgatgta gagatttggg aatttctcgc taaagaagct
    10561 ggcgatttca ggattgattt caatgacttt tgtatcgata cgactatctt tgagaatacc
    10621 aagtagataa taggcaattc tacctgcccc aacgatgaga aggctcttca cggcgcgtga
    10681 tttaaaataa ttatggaaga gtatcatatc gacacggtta ccagtgacaa agattctatc
    10741 tttatcctgt acagtcatgt caccgcttgg aatgataatt tgatgatccc tctctatcgc
    10801 acagacaatg acattaccaa attttttacg aaaatcagaa atgggcattt ggcaaagacc
    10861 gctggtggac ttgacgacaa attccatgag gctaacgcgt ccaccagcaa agcgttcgac
    10921 agacagggcg ttggggaagt caatgatatt cgcgatagcg cgggcagcca agagctcagg
    10981 attaacgata agagaaaaac cgagaatatt cttttccttg aaataagagt tagaatattc
    11041 agggttccgc acccgaacga tagtttcttt agctcccatt ttcttggcta gaactgctgc
    11101 aatcatgttg acttcatcgt gctcagtcag ggcgataaag atatcacaat cttggacgct
    11161 ggcttgctca agaatggcaa aatcggcccc gttaccaagg ataccaatga tatcaaagcg
    11221 actgacaata tgattgagaa cagcttcgtc ttgctcaatc agcaaaacat catgcttttc
    11281 tgcaaccaag gagcgacaga gggcaaaacc aacttttccc cctccgacaa ggataatttt
    11341 cataataaaa cctacttttt catgatgtaa ctatcatacc ctttttcaag aaaaaatgca
    11401 cctactagct aataaccaga gtttttagta ggaaatttgc tataagttaa aactataccc
    11461 taaccaattg aaatagctat tagcgacttt ctctgaaata tggtatgata aaggatatac
    11521 aaggagataa aatgaataat aatttactgg tattacaatc agactttggt ctggttgatg
    11581 gtgcggtatc ggctatgatt ggagtggctt tagaagagtc tccaacctta aaaatccatc
    11641 acttgacgca cgatatcacg ccttataata tttttgaggg gagctatcgt ctctttcaga
    11701 cggtggatta ctggcctgag ggaacgacgt ttgtatcggt tgtcgatcca ggtgtcggtt
    11761 cgaaacgtaa gagtgtagtt gccaagactg caaaaaatca atacattgtc acgccagata
    11821 atgggacgct ttcctttatc aagaaacacg ttggcattgt agccattcgt gagatttctg
    11881 aggtggccaa taggcgtcaa aacacagagc attcttatac cttccacggt cgtgatgtct
    11941 atgcctatac tggtgctaaa ctggccagtg gtcacattac ttttgaggaa gtagggccag
    12001 agctcagtgt ggaacagatt gtagagcttc cagtcgtagc gaccatcata gaagatcatc
    12061 tggtgaaggg agccattgat attctggatg tgcgtttcgg ttcgctttgg acctctatca
    12121 cacgggaaga attttacaag ttggaaccag aatttggtga tcgttttgaa gtgaccatct
    12181 atcatgctga tatgctggtc tatcaaaatc aggttgtcta tggcaaatca tttgcagatg
    12241 tgagaattgg gcaacccatt ctttacatca actctctcta tcgtttaggt ttggctatca
    12301 accaaggttc ctttgccaag gcctataatg taggtgtcgg ttcatcttgg accattgaaa
    12361 taaagaaaat agaaggataa aataggagaa tagtatggaa atcaaattta caattaaaca
    12421 agttgttgct gtcggaattg gcgctgccct ctttgtcgtc atcgggatga tcaacattcc
    12481 aacccctgtt ccaaatacaa gcatccagct tcagtatgcg gtacaagcgc tactttctat
    12541 tatttttgga ccgattatcg gtttgcttgt tgggttgatt ggtcatgcaa tcaaggactc
    12601 tcttgttggt tatggtctat ggtggacttg gattatcgct agcggactct ttggtttagt
    12661 tgtgggactt tttagaaagt acgttcgcgt gatcaatggt gtttttgact ggaaagatat
    12721 tcttattttt aacctcattc aactacttgc aaatgccctt gtttggggtg tcttggcacc
    12781 acttggagat gttgtgattt atcaagaagc ggcagaaaaa gtatttgcac aaggaattgt
    12841 tgcgggaatt gccaatggtg tatctgtagc tattgcagga actcttctct tacttgccta
    12901 tgcaggaact caaactcgtg caggaagttt gaaaaaggac taatactcaa tgaaaatcaa
    12961 agagcaaact aggaagcaag tcgcaggttg ctcaaaacag tgttttgagg ttgtagatga
    13021 aactgacgaa gtcagtaacc atacctacgg caaggcgaag ctgacgtggt ttgaagagat
    13081 tttcgaagag tataaaatga tggggaaggc tgggcaacta gtctttttcg atgtttatag
    13141 attagttagg caagtaagct aggataggaa tctttttggc gctaagattt taagagaaga
    13201 gactgcaaga agggcttgat ttatgataaa atagaagtct aagaagcgaa tgaagagagt
    13261 aagatgaaag aagctataat tgagtggaag gatttctctt tccggtatga aacacaacaa
    13321 gaaccgacct tgcaagggat agacttgacc atttacaagg gagagaaagt cttaattgtt
    13381 ggaccatctg gatcaggtaa atctaccttg ggtcagtgtt tgaatgggat tattcccaat
    13441 atttacaagg gtcagacata tggagaattt ttgataaagg gtcaaacagc ctttgatatg
    13501 agcatctatg ataagtctca tctggttagc acagttttgc aggatacaga tgggcagttt
    13561 attggcttgt ctgtggcaga agatttggcg tttgctctgg aaaatgatgt gacagcccta
    13621 gatgagatga aaggtcgtgt ttataaatgg gctgaaaagc tggaccttct tcctttactg
    13681 gatcagcgcc ctcaggattt gtcaggtgga caaaagcagc gagtcagtct ggctggtgtc
    13741 ttgattgatg aaagtccgat tctcttgttt gatgagccac tcgccaatct agatcccaag
    13801 tcaggtcagg atattatcga attgattgac cagattcata aggaagaggg gacgacgact
    13861 ctgattatcg agcaccgttt ggaggacgtt ctgcatcgcc ctgtggatcg gattgtcttg
    13921 ataaacgatg gtcgtatcct ttttaatggg agccctgacc agttgcttgc gactgattta
    13981 ttgactcaaa atggaattcg agaacccctt tatctaacga ctctccgtca attaggtgtg
    14041 gacttagtca aggaagaaca attagcagat ctggataact tgtctatctc aaaagggcaa
    14101 gtccagttac agacggaact ggtaaaagaa accccagaat tgcagtcact ctttagacta
    14161 gaggaagtat ctttttctta tgatgataga ccgattttaa aatccctaca tttagatatt
    14221 aaaaagggtg aaaagattgc tattgtcgga aaaaatggag cagggaaatc aactctagcc
    14281 aaggctataa gtagctttat tcagacggaa ggacgctatc tttgggaaaa acaggatata
    14341 aaaggcgatt ctgttgcaga gcgggcggaa cgagtaggct atgtgctaca aaatcctaat
    14401 caaatgattt caaccaatat gatttttgat gaggtggctc tagggctccg tttgcgaggt
    14461 gtggatgaga aggaaattga aacgagagtc tatgaaacct tgaaaatctg tggactttat
    14521 gaattccgta attggcctat ttctgccctg tcatttggtc agaaaaaacg tgtcaccatt
    14581 gcttcaattt tggtcttagg agctgaaatt attctcctag atgaaccgac tgcaggtcaa
    14641 gatcagaaga actatactga gattatggaa tttctcgaag agttacatca aaaagggcat
    14701 accattgtca tgattaccca tgatatgcaa ttgatgctgg attattcaga ccgggtcctt
    14761 gtcatggtgg atggagaatt gattgccgat actgttccag ccagtctgtt gagcgatcct
    14821 gagctgttag taaaagccaa tctaaaagaa acctccatct ttaacttggc taagaaacta
    14881 gatgtggatc cactggattt aacggcattt tacaaagaaa ggagagaggg atgcaagcta
    14941 aattaatcgg ttaccagcat agagatactg tgattcatcg cttgtcagga gctgggaaac
    15001 ttctcttttt cattctggta tcattggcgg ccatgattag ctatgatacc agaatgctct
    15061 tgctgattgc catcttttca gtctttctcc tctatttatc agaaattcgc tttaaagatg
    15121 tttcctttgt agccgttttt gcgacggtat ttgccgtttt aaacgttttg atggtctatc
    15181 tcttttctcc cgagtatggg gttggacttt atggagagag aagtgtgatt tggcagggaa
    15241 tcggtgtcta cactctaacc agccaggagc tcttttatct gctaaatttg gccattaagt
    15301 atctttgcac cattcctctg gctattatct ttttgatgac aacccatcct agtcagtttg
    15361 cttccagttt aaatcaaatt ggtgtgccct ataagattgc ttattctgtc agcctgacct
    15421 tgcgctatat tccagatttg caggaagaat tctttactat caagatgtct caggaggcgc
    15481 gtgggatgga attatccaag aaagcttctc ttatgcaacg aatcaaaggc aatctgctca
    15541 ttattacgcc cttgattttt agctcgctag aacgcattga taccattgcg actgccatgg
    15601 agcttcgccg ctttgggaaa gagaaaaaac gcacatggta tagttatcag gccttgaaaa
    15661 aaggagacta tattaccttg ctcttggcaa ccttgttttt agtagttagt ttactactta
    15721 tcttgcagaa tcagggacga ttttacaacc cttggaaata gcttgaaaaa attgaaaaaa
    15781 tcaagtcgtt tctattgaca atgattctga aagtgttata ctaagaaagt agtttcgctg
    15841 atttacttca aacctgttgt gaggtaagtt aacgatgcct taaccacgct gtttgctgag
    15901 cttgactccg ggcagtgtgg ctattttttt gcaatggtga aaggaagcaa gtcatgacaa
    15961 atcacattgt attatttgaa cctcaaattc cacaaaatac gggcaatatc gcgcgtactt
    16021 gcgctgcgac caattctccc ctccacatca tcaagcctat gggctttcct attgatgacc
    16081 gcaagatgaa gcgggctgga ttggattact gggataagct agagatttat ttttacgaga
    16141 gtttggaaga tttcatatct cagatgaagg gaaaactcta tctgatttcg aaattcgcgg
    16201 aaaaagtcta ttctgaggtg gatttatcga ctgacgagga ccattatttt ctctttggac
    16261 gtgaagacaa gggcttacct gaagatttta tgcgagaaca tcctgagaag gctctccgta
    16321 ttcccatgaa tgatgaacat gtccgcagtc tcaatgtgtc taataccgtc tgcatgattg
    16381 tctatgaggc tcttcgccag cagaactttg caggtcttga gctcgtccat acctatgaag
    16441 tggataaatt gaaataaaaa atgaaaatga acaaaatgct tgcgcttgca agcgtttttt
    16501 gttatgataa aagagtcttc agggcagggt gtgattcccg accggcggtg actttaacta
    16561 ggaaatgatc ttttcctttt atactttgtt gacaagcttt gcctaaccag aagttatgcc
    16621 tacagcttgt cgcctagtct aaaagaaaaa tctctatttc cttctcttta aagaagtccg
    16681 cgagcgcaag ctgatgtggt gagattccac aaccgacagt atagtctgga tgggagaaga
    16741 cgaaagaata gctttgtctg ttttgataga tttatagccg gattgtaacc acttgctttg
    16801 tttttcttta atagagtaag agggaacttt tgggatataa aaagtgagaa tagatagagg
    16861 aatcctttcc aacttcttct gattttatag aaaattggag gaacctgtta tgacaaatac
    16921 acgtcgactt tcgaccattg caattttatc agccatctca tttgtgctga tgtactttga
    16981 ctttccgctt ttaccagcgg catctttcct caagatcgaa tttagtatct tgccagtcct
    17041 tgtgggtctg gtggtcatgg atttgcctgc tgctctagga gtgctcttgc ttcgctcact
    17101 cttgaaattg cttcttaaca gccaaggagt gaatacttac attggtttgc cgatgaatat
    17161 cgtagctttg ggagtttttg tcatcgtatt tgctttgatt tggaaaaagg aacggacaac
    17221 ccttcgtttc ctactaggct ctctagctgg aactgttggt ttaaccttgg ccatgttggt
    17281 tctcaactat gtttatgctg ttcctttgta cgctaagttt gctaactttg atattggaaa
    17341 aattttggga ctttccaact acctaatgac catggtatta ccttttaact tgattgaggg
    17401 tgtaatcttt tccgtttcat tctggttgtt gtacgtcctt ttgaaaccaa ccttaaaaca
    17461 ctatgaaaga taaacaaaca tttttaatga agggcagttt tgccctttta cttttcgtta
    17521 ttcttggcta tatggtcaaa ttttaccctg aaatgttggt caattttgac caatcgattc
    17581 agactgccat tcgaggagac ttaccagatt atttgactat tctttttcga gccctcacac
    17641 gtctgattga tatcccagtg attatcactt gggttgtcat tacagctttt gtcttttatc
    17701 gtaagcgatg gaagatagaa agtttcttca tgctgggaaa tctggctttg gcaggtcttt
    17761 taatcgtgac ctttaaaaat atctaccagc gcccacgacc agctatctta catctggtgg
    17821 aagagaaggg attttccttc ccaagtgggc attctctggc tgtaactttg atggtaggta
    17881 ctctgattgt cattctcagt caacgaatta aaaatccagt ctggagaaaa atcgtacaaa
    17941 tcgtccttgg cctctaccta gtcagtgtgc tggtatcaag agtctatctg ggagttcatt
    18001 acccatcaga cgtccttgcc agtctctgtg tgggcttggg agtcctgttt atcgagtttc
    18061 ccttctatga caagctccgc ttccaatggc gatttaaagg caaacagaag tgagtatcga
    18121 attcccttga ggagaaagaa atgaaagtca atatagcaga tcttcatctg actcaactat
    18181 atttatcaga aaagaagttg caagatattc agatgcttta ccagtcggca gaaacaatcc
    18241 aagtcgatcc aatcagtatt cttgcctttg gagattgttt gctgattaca gatgggcatc
    18301 acagggctta tcaggcttta ttggcaggtc gggatacgat ttctgctgag tgggatagag
    18361 atggtggtga tgaactatat catctctatg cgcaagcttg cgaggaaaga aagatttact
    18421 ctgtttttga tttagaagat cgtatcctag ctcaagatgg gtatgaagca aaatggtata
    18481 actggtgtga tggttttaat caagcagcaa ctcttttgtt gaaaaggtag tgcattgtgt
    18541 tttgttcctt attataaggt caatcattgt gaggaagctt ttgcttggta tcaggatgtg
    18601 aacttggttt acctcgtaga tggggtgaag cttccttaca gtcaagcgac cttggaagcc
    18661 atgtattcct atttggatcg gcatggtgag cttttttgga ttgaagtcaa ggagaaggga
    18721 gaatggtttc caattgggga tattacacta tctcaggata atctccccat tgtgattggg
    18781 aattccgctt accaacatcg aggacttgga aaaaagattc taagtgcttt gattgaattg
    18841 gctcgagtaa aaggatggaa agaattgaga gtcaagaaaa tctacaccta caatcatgct
    18901 tctaggaggt gtttcaagtc gcttggattt gtggaaaatg gagcaacaga aaaaggaatg
    18961 agttttatat tggaattagt ctaatcctgc cactttctcc cccttaacct ttgactattc
    19021 cgcaaaatta tcgtaaaata aagagtgaat gataaaatga ggtcagagtc tgttcgctct
    19081 ggcgatagta gtataaatga ggagaaacgc tttgaaatta gaagtatttg ctgggcaaga
    19141 aaaaagtgaa ctatctatga ttgaggtagc gcgtgctatc ttggaacttc gtggtcgcga
    19201 tcatgagatg cattttagcg atcttgtaaa cgaaattcaa aactaccttg gaacatcaaa
    19261 cagcgatatc cgcgaagctt tgcctttgtt ctacacagag ttgaactttg acggtagctt
    19321 catctcactt ggggacaaca aatggggtct tcgttcatgg tatggtgtgg acgaaatcga
    19381 cgaagaaatc atcgctcttg aagaaaatga cgacgatgaa gtaacaccaa aagctaagaa
    19441 aaaacgtgtc aatgccttta tggatggtga ttcagatgcc attgactaca atgcagatga
    19501 tccagaagac gaagatgcat acgaagcaga tccagctctt tcatacgatg atgaaaatcc
    19561 agatgatgaa aaaaatgaag tggaagctta tgatgcagaa atcaacgaaa tcgctccaga
    19621 tgacttggga gaagatgtgg atctcaacga agacgacgac gagttttcag acgacgacgc
    19681 tgaaaccagc gaggaataag agttagctat tgacaattat cctattttta ggtatcatat
    19741 tgtttgggca cctcttttag aggtcggggc tccctagttc ttagggagct atttttgttt
    19801 tttcaagaag ttatcttctt gtattttata ctcaatgaaa atcaaagagc aagctaggaa
    19861 actagccgta ggctgctcaa aacactgttt tgaggttgta gataagactg acaaagtcag
    19921 gaacacatat ctacggcaag gcgacgttga cgcggtttga agagattttc gaagagtatt
    19981 agttgtgaat ctggtgcagt cgtcccagat tattcttatt agtagggtct tgttttctat
    20041 atcccctcgt agttaacaag accttgagca ttttagaaag aggaatctat gtctacgaaa
    20101 tatatttttg taactggtgg tgtggtatcg tccattggga aagggattgt ggcagcgagt
    20161 ctaggccgtc tcttgaaaaa tcgtggtctc aaagtaacca ttcaaaagtt tgacccttat
    20221 atcaatattg atccgggaac catgagtcct taccagcacg gggaagtttt tgtgacagat
    20281 gacggagctg agacagattt ggacttgggt cactatgaac gtttcatcga tatcaatctc
    20341 aacaaatatt ccaacgtgac aactgggaaa atttacagtg aagttcttcg taaagaacgc
    20401 cgtggagaat accttggggc aactgttcaa gtcattcctc atatcacaga tgctttgaaa
    20461 gaaaaaatca agcgtgccgc tctaacgacc gactctgatg tcattatcac agaggttggt
    20521 ggaacagtag gagatatcga gtccttgcca ttcctagagg ctcttcgtca gatgaaggca
    20581 gatgtgggtg cggataatgt catgtatatc catacaacct tgcttcctta cctcaaggct
    20641 gctggtgaaa tgaaaaccaa accaacccaa cactctgtca aagaattgcg tggcttggga
    20701 atccaaccaa atatgttggt tattcgtaca gaagagccag ctggtcaagg aattaaaaat
    20761 aaactggccc agttctgtga tgtggcacca gaagccgtta tcgaatcgtt ggatgttgaa
    20821 cacctttacc aaattccact gaacttgcag gcacaaggga tggaccaaat tgtttgtgat
    20881 catttgaaat tagacgcacc agcagcggat atgacagaat ggtcagccat ggtggacaag
    20941 gtcatgaacc tcaagaaaca agttaagatt tcccttgttg gtaagtatgt ggagttgcaa
    21001 gatgcctata tctcagtggt cgaagccttg aaacactctg gctatgtcaa tgatgtagaa
    21061 gtcaaaatca attgggtcaa tgccaatgat gtgacagcag agaatgtagc agaactcttg
    21121 tctgatgcgg acgggatcat cgtaccaggt ggttttggtc aacgtggtac agaagggaaa
    21181 atccaagcca tccgctatgc gcgtgaaaat gatgttccaa tgttgggagt ctgcttggga
    21241 atgcagttga catgtatcga gtttgctcgt cacgttttag gtcttgaagg tgccaattct
    21301 gcagagcttg caccagaaac aaaataccct atcattgata tcatgcgtga tcagattgat
    21361 attgaggata tgggtggaac ccttcgtttg ggactttatc cgtctaagtt gaaacgtggc
    21421 tctaaggctg ctgctgctta tcacaatcaa gaagtggtgc aacgccgtca ccgtcaccgt
    21481 tatgagttta ataatgcctt ccgtgagcag tttgaggcag caggttttgt cttttcagga
    21541 gtttctccag acaatcgttt ggtagaaatc gtggaaattc ctgaaaataa attctttgta
    21601 gcttgtcagt atcaccctga actgtcaagc cgtccaaacc gaccagaaga actctacact
    21661 gcctttgtta ctgcagcggt tgagaacagc aattagcaaa atcagaacct ttgagaaaaa
    21721 tctcagaggt tttttgcata cgatgatatt gcagtatatc tgaggtaggg gtcctctgta
    21781 tgtacctgct accgttgaaa tcaatagcga ctccctcttg ccctgtgcta gtgaatggat
    21841 ttatcagtat attgaaatga aataaaattt gaacaaatta attcggaaag ccaaatcaat
    21901 ttctagcaaa gttttaggaa ctggattgta tagtgaattg aaataagatg tgaacatctc
    21961 tatcagaaaa gtcaaatta
//
LOCUS       DAVMCG010000031        21809 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVMCG010000031 DAVMCG010000000
VERSION     DAVMCG010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.032"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(100..297)
                     /gene="blpI"
                     /locus_tag="VYP66_001442"
     CDS             complement(100..297)
                     /gene="blpI"
                     /locus_tag="VYP66_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HEV1850986.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            587..1174
                     /locus_tag="VYP66_001443"
     CDS             587..1174
                     /locus_tag="VYP66_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEV1850987.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1101..2744
                     /locus_tag="VYP66_001444"
     CDS             1101..2744
                     /locus_tag="VYP66_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1850988.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            2755..4116
                     /locus_tag="VYP66_001445"
                     /pseudo
     CDS             2755..4116
                     /locus_tag="VYP66_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            4173..4328
                     /gene="blpC"
                     /locus_tag="VYP66_001446"
     CDS             4173..4328
                     /gene="blpC"
                     /locus_tag="VYP66_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1850989.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(4370..5710)
                     /locus_tag="VYP66_001447"
     CDS             complement(4370..5710)
                     /locus_tag="VYP66_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1850990.1"
                     /translation="MNIAWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(5724..6461)
                     /locus_tag="VYP66_001448"
     CDS             complement(5724..6461)
                     /locus_tag="VYP66_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850991.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFEYRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6466..6804)
                     /locus_tag="VYP66_001449"
     CDS             complement(6466..6804)
                     /locus_tag="VYP66_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1850992.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7080..7409
                     /locus_tag="VYP66_001450"
     CDS             7080..7409
                     /locus_tag="VYP66_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1850993.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLDSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLSL
                     YGPTIIL"
     gene            complement(7470..8519)
                     /locus_tag="VYP66_001451"
     CDS             complement(7470..8519)
                     /locus_tag="VYP66_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1850994.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPTLLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWIFVQTLFLLLFAPLFLVMGYGLPVFLVYVLLLGVGKYFLFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKVVQKVSGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSLLAQVFIEQSWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLISFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8516..9247)
                     /locus_tag="VYP66_001452"
     CDS             complement(8516..9247)
                     /locus_tag="VYP66_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1850995.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9315..9725
                     /locus_tag="VYP66_001453"
     CDS             9315..9725
                     /locus_tag="VYP66_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1850996.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            9735..10022
                     /locus_tag="VYP66_001454"
     CDS             9735..10022
                     /locus_tag="VYP66_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850997.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10184..10423
                     /locus_tag="VYP66_001455"
     CDS             10184..10423
                     /locus_tag="VYP66_001455"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1850998.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHGKPTLTWFEEIFEEYHSPFHN"
     gene            complement(10745..11881)
                     /gene="dnaJ"
                     /locus_tag="VYP66_001456"
     CDS             complement(10745..11881)
                     /gene="dnaJ"
                     /locus_tag="VYP66_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1850999.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12283..12639)
                     /locus_tag="VYP66_001457"
     CDS             complement(12283..12639)
                     /locus_tag="VYP66_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1851000.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(12641..14464)
                     /gene="dnaK"
                     /locus_tag="VYP66_001458"
     CDS             complement(12641..14464)
                     /gene="dnaK"
                     /locus_tag="VYP66_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1851001.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(14944..15468)
                     /gene="grpE"
                     /locus_tag="VYP66_001459"
     CDS             complement(14944..15468)
                     /gene="grpE"
                     /locus_tag="VYP66_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1851002.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15495..16529)
                     /gene="hrcA"
                     /locus_tag="VYP66_001460"
     CDS             complement(15495..16529)
                     /gene="hrcA"
                     /locus_tag="VYP66_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1851003.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVHLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16693..17203)
                     /locus_tag="VYP66_001461"
                     /pseudo
     CDS             complement(16693..17203)
                     /locus_tag="VYP66_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
     gene            17811..20144
                     /locus_tag="VYP66_001462"
     CDS             17811..20144
                     /locus_tag="VYP66_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1851004.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKAHRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20157..21620
                     /locus_tag="VYP66_001463"
     CDS             20157..21620
                     /locus_tag="VYP66_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1851005.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINAIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTNDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21620..>21809
                     /locus_tag="VYP66_001464"
     CDS             21620..>21809
                     /locus_tag="VYP66_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HEV1851006.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         6926 a         4438 c         4012 g         6433 t
ORIGIN      
        1 ttattctcat cattcttaga taactttgat attttgtaag taagtaaata agacagtaaa
       61 ttaatagcga taataatact atatttaaga atcataatct tacaaagagg acataattcc
      121 tgaacctaca caaataagtg ttgctgctcc cccagttatc ggaccagtcg cagcagctaa
      181 tagtactgct ccaatacaac caccgattgc agatcctaaa ttgcctcttc ctccactaac
      241 tatttcgagt tcttcattat ccataacaga aaattgttcc atcatttttg tattcatgac
      301 aaatactcct tttttatttt tgtcttgttg taactttgat aagtttagta tatcatcgtt
      361 ttttaaaatt tttcatccag atcttgaatt gtcatcgaaa cgtcttgaat tagctttttt
      421 atttcaagcc acctctattt caagccacct ctaaatgttt aaaaaaaata atttctaatc
      481 acttttttac cattcaggaa gttttaatga ctattcaaga tttcataaaa tatgaactta
      541 gttttatgac ataatagacc tatccactat atgaaaggaa ttgccaatga cttcttataa
      601 acgtacattt gttcctcaaa tagatgcgag agactgtggt gtcgctgcct tagcctcgat
      661 tgctaaattc tatggttcag atttttctct agctcacttg agagaacttg caaagaccaa
      721 taaagaaggg acgactgctc ttggcattgt aaaagccgct gatgaaatgg gctttgaaac
      781 aagacctgtt caagcagata aaacgctctt tgacatgagt gatgtcccct atccatttat
      841 cgttcacgtt aacaaagaag gaaaactcca acattactat gttgtctatc aaacaaagaa
      901 agactatctg attattggtg atcctgaccc ttctgtaaaa atcactaaaa tgtcaaaaga
      961 acgctttttc tatgaatgga ctggagtagc tatttttcta gctaccaaac ccagctatca
     1021 accccataaa gataaaaaga atggtctact aagcaagctt ccttcctctg attttcaaac
     1081 aaaaatctct cattgcttac attgttctct caagcttatt ggtcactatt atcaatatag
     1141 gtggttctta ctatctccaa ggaatcttgg atgaatacat tccaaatcag atgaaatcaa
     1201 ctttaggaat catctcagtt ggtctggtta tcacctatat cctccaacaa gtcatgagct
     1261 tctccagaga ttatctccta accgttctga gccagagatt aagcattgat gtgattttat
     1321 cctatattcg ccatattttt gaacttccca tgtctttctt tgcgacacgt cgtacaggag
     1381 aaatcatttc acggttcaca gatgctaact ctattataga tgtcttggct tctaccattc
     1441 tttctctttt tctggatgtt tctattctga ttcttgtagg gggagtcttg ctggcacaaa
     1501 accctaatct cttcctcctt tctcttcttt ccattcctat atacatgttc atcatctttt
     1561 cttttatgaa accttttgaa aaaatgaacc atgatgtcat gcaaagtaat tctatggtta
     1621 gctctgccat tatcgaagat atcaacggga ttgaaactat aaagtcgctc acgagtgaag
     1681 aaaatcgcta tcaaaatata gacagcgaat ttgtagatta tttggaaaaa tcctttaagc
     1741 tcagtaaata ttctatttta caaacgagtt taaagcaggg aacaaaatta gttctgaata
     1801 tccttatcct atggtttggc gctcaattag tcatgtcgag taaaatttct atcggtcagc
     1861 tgattacctt taacacactt ttttcttact ttacaactcc tatggaaaat attatcaacc
     1921 tccaaaccaa actccaatct gcgaaggtcg ctaataaccg tttgaacgaa gtctatctag
     1981 tcgaatctga atttcaagtt caagaaaacc ctgttcattc acattttttg atgggcgata
     2041 ttgaatttga tgacctttct tataagtatg gttttggacg agatacctta acagatatta
     2101 atctcacgat taaacaagga gataaggtta gcctagttgg agttagtggt tctggtaaaa
     2161 caactttagc caaaatgatt gtcaatttct ttaaacccta caaagggcat atttccatca
     2221 atcatcagga tattaaaaac attgataaaa aagtcttgcg ccgtcatatt aattacctac
     2281 cccaacaagc ctatatcttt aatggctcta ttttggaaaa cttaaccttg ggcggtaatc
     2341 atatgattag ccaagaagat attctaaaag cttatgaatt agctgaaatt cgtcaagaca
     2401 ttgaaagaat gcctatgggc tatcaaactc agctctctga tggagctggt ctatcaggag
     2461 gacaaaagca acgaatcgct ctcgctcgtg ctcttttaac taaagctcct gttttaatac
     2521 tagatgaagc tactagcggt cttgatgtct tgactgagaa aaaggttata gataatctta
     2581 tatccctaac tgataaaacc attctctttg tagcccatcg tctcagtata gccgaacgaa
     2641 ccaaccgtgt cattgttctt gaccagggga aaatcattga agttggtagt caccaagagt
     2701 taatgcaggc gcaaggcttc taccatcatc tattcaataa ataaggagaa tgtcatgaat
     2761 cctaatcttt ttagaagcgt cgagttttat cagagacgtt accataacta tgcgacagta
     2821 ttaatcatac ctctgtcatt actgtttact ttcatcttga ttttctccct tgttgccaca
     2881 aaagaaatta ctgttacttc ccaaggggaa atcgccccta caagtgtcat tgcatctatt
     2941 cagtcgacca gtgataatcc tatccttgct aatcatttag tggcaaatca agtagttgag
     3001 aaaggtgact tactcatcaa atactctgaa acaatggaag agagtcagaa aactgcctta
     3061 gaaactcaat tacaaagatt tgagaagtaa aaagaaggac ttggaatttt gaaacaaagc
     3121 ttagaaaaag cgactgatct tttttctggc gaggatgaat ttggctacca taataccttt
     3181 atgaatttta ctaaacaatc ccatgatatt gaactgggta tcacaaagac taacactgag
     3241 gtttcaaatc aagctaatct tgccaatagc agttcatcag ctattgaaca agaaattaca
     3301 aaagttcaac aacaaattgg agaatatcaa gagctgagag atgctatcat aaataacaga
     3361 gcacgcttac caactggcaa tccgcaccag tcaattttaa atcgttatct tatagcctct
     3421 caagaacaaa cacaaggaac ggcagaggag ccatttttat ctcaaattaa tcaaagtatt
     3481 gcaggtctgg aatcatctat cgcaagcctc aaaattcagc aagctggtat cggaagtgta
     3541 gcaacttatg ataatagttt agcaaccaaa attgaagtac tccgcactca gtttttacaa
     3601 acagcctcac agcaacaact aaccgtggag aatcaattaa cagaattaaa agtacaacta
     3661 gatcaagcaa cgcagcgctt aggaaacaat accttaaccg ctccaagtaa aggtatcgtt
     3721 catctgaaca gcgaatttga aggtaaaaat agaattccaa ctggtacaga aattgctcaa
     3781 atattccctg tcatcacaga tacaagagaa gtactaatca cttactacgt atcttctgac
     3841 tatctacctc tactagataa aggacaaact gtaagattaa aactggagaa gattggaaat
     3901 cacggcacca ccatcatcgg ccaacttcag acaattgatc aaactcctac cagaacagag
     3961 caaggcaatc tctttaaatt aaccgctctt gcaaaactat ctaatgagga tagtaaactc
     4021 atccaatatg gcttacaagg tcgcgtcact agtgtaactg caaagaaaac atattttgat
     4081 tatttcaaag ataaaatttt aacccattct gattaatttt cagataacac tctataacta
     4141 tttattatct tatcaaaaag gagaatcata acatggataa gaaacaaaac ctaacttcat
     4201 ttcaagaact aacaactacc gaactcaacc aaattacagg tggaggatgg tgggaagaac
     4261 tcttacatga aacaatttta agtaaattta aaatcacaaa agcacttgaa ctacctattc
     4321 agctataaaa acaagaccga gaaacaagaa ctctcggtct tgttttttat cattctgcat
     4381 gtatcacagt aagtacctga cgaaagactt gattttggca ggtagtattt agattggtat
     4441 tgggatgact ttccacaatc ttcataacgg tatagagacc aactcctctc tcctcccctt
     4501 tagaactggc tccaaaggag aagatttcag aaatatcgat gccctcttct ttgatggagt
     4561 tttcaatgat aaaagtctcc tgtgctccat tttttaaaaa ggcgattgaa acatgaggtt
     4621 gactggcctc tgcactagct tcaatagcat tgtcacaaag gatagacaca atggttagaa
     4681 aatcaagtag gctcatcccc tcaacctgaa tctcctcagg aacttcaaca ttaaagacaa
     4741 tgttcttttc tctagctttt ataaattttc cagctaggag actcttgagg gcacggtcac
     4801 gaatattcac caatctgccc aggtcatatt tattgtcctg caatttctga ctggaatccc
     4861 ttaagaccga gtcgtagatc tcttttatct gctccatatc ctcctcttca atgcccaaac
     4921 gtaagctggt taagaggtta gtgtagtcat ggcgaaaact ccgaatttcc ttgtaaagtt
     4981 cctctatatg ccgactatag cgttccatat ctctgtagcg caaggtctgc tcttggttca
     5041 gttcctcctg aagtttttcc ttcaaatagg tatccaattt cttgataccc cccataaaaa
     5101 agagtaggta aaacactagg atgagatggc gaacagtcgt tgattgaata ccttgttcat
     5161 attcaaggta agatagactt tgcatcacta gataataagc ccccattgcc cagttaatct
     5221 tagtaagaga cttttgaaaa cctgtatcta gaaactccct tctcaatcta gtgaaatcat
     5281 agtctaacca tttcaaaaag actaaaacta tgaagcaaac gaatatcata atcaataaaa
     5341 agataggatt gccatcccca tctacaattc cttgccccaa aaatggaagc acaaaatagg
     5401 aaacacctct gtaaaagagc tctactaata tcattgggaa gagaccataa aaaataagga
     5461 tttttttagg aagccctctt aacaataaga aagatagacc tataccgaac aaaggttcta
     5521 taaaatagga caaatattta cttacagcca aaaattgaaa agtcgtaaaa atgatcccta
     5581 gaagaaattt cagaagaaag gccttaaaaa ttctatcgaa agtgagacca attccatcta
     5641 ctttaaagaa aatgacaatt tctagtccat taataacaag tgcatacaac aatatccaag
     5701 caatgttcat aaactctcct agctcagtgt aagttattaa tagcctcaga cacttccctg
     5761 accttataac gcgcgatcag acaacttcca ccattgggaa agaaaaggag tttttctttc
     5821 ttatccaaat gcaccacatt tgcaggattg atgagaaaag agcgatggca ctgcaagaga
     5881 cggggttcct gcttgaaaac ctcctctaaa ctcgctgtaa attccagcct gtctgtcttg
     5941 gtatagagaa taacacgatg gggtcttggg gatgtttcga gatagtaaac ctctttaaaa
     6001 ggatactgaa attgggcaaa ttttgattta aagtaaaagc aatcttccgc cagactttta
     6061 ctatcttgac tattggcata gaggagagct gtctcgattc gatattcaaa ctcctctgcc
     6121 gaaagggcct tatcaatata gtccagagca gacacttggt agcgaaagga caggggcata
     6181 aactccgagt gagtcgtcac aaagacaatc agggcatagg ggtcttgttc ccgaatcttt
     6241 ctagccactt ccagcccctt catctcctca tttcgaatct caatatccaa aaagaatagc
     6301 tgatgggccc ccttctcatg cacctctgcc agcagttggt ctggcttgcc aaatacctca
     6361 aaagagctgg gagtgatatg atgttccttc aagagtttct caatcgtcgt ttcaatccta
     6421 gtctgttggg aaaaatcatc ctctaaaaca aatattctca tctttttact ctccctcttt
     6481 caaccatttt tgacgtattt ctctatagcg acgtctggca tacttgacag cgtattgacc
     6541 ttcttctccg agaaaaagga ttctttcttg aaaatcaatc gattttaatt tatcaagatt
     6601 aaccaaacaa tttcgatgac atctcatcaa agtttcccca cattggttct caagattact
     6661 taaattttga agcatattaa aactagcttt ttctgtaaca atctgtacgg tatgggcttt
     6721 agttggatgt gtttggatat agtagatatc gtcgatgttt actttataga ctgttttctg
     6781 tgtctgaata atcatatgtt tcattggatt ctcctcctaa gaaaagaata acagaaaagg
     6841 tctagcccaa gcacacccaa tcctaaacag tctttgaaaa ctcctaaaag gattattttc
     6901 tacaacatca tgatgagctt acaactattt tatcataaaa ttcactcagc gcaattcaag
     6961 acatttcaat gacaattaaa gatttgaata aaaaaaaaga attaaaagtg ataaactaac
     7021 agtatcaaaa cacagttgcc agaagtaaga ctggcaccca gattaaagga ggcattccca
     7081 tgacagatac agaccccatc aaaagagctc acactttgat tactgactta aacaaagcct
     7141 accaagcatg caaacaggca agcgctgacg acgtccgctt tcaagagcaa ttagactcta
     7201 ttcttggttt tctagccaag gctgagacag tggataatcg attcttgatt gaactggaaa
     7261 aattttacca gacttccagt cttctcatgg gactcagcgc tcttgatcca gatgctccaa
     7321 ctcgcgctgc ttggcgagcc tatgaccgct tccactttga ccaagtcaag accaagttga
     7381 gtctctacgg accaaccatt atcttgtaga aaataaaaga agttgagaca aactgaactc
     7441 aacttctttt ttagtgtcat ataagcatct tagtcctgca tctgacgttt tacctgataa
     7501 ggtaggtaca agactagtaa aaccaaacca gctcctagta aggctagaag ggctagtttt
     7561 tcttggaagg taatcaaccc aacaactaat tccacaagta aaacaaaact gatcaatcct
     7621 cgaactacct cctgtaagcc tttttccttt tgccccttgt ccagcggaaa gagttgggtc
     7681 aaatactggt agtcaaaggc atgatagagg gccagcaact ggaaaagcaa gaggtagtta
     7741 aagagaacta ccactgctgt cgcaatccaa gattgctcga taaagacctg cgccagcaaa
     7801 gaaagcaaga gcagacggag actaagggca aaaaggtctc catttcgcaa ataagaacgc
     7861 agatagagat tttgccaaat cttcccagac accttctgaa caacctttag aataaagtcc
     7921 agataggcac gacgcttgac gctgtttgaa attcccttga cctgcgtaaa gagggcaaag
     7981 aaacgaagca agacttgctt acgcttgctt tcttgggaaa tgacatagtc ccaatccagt
     8041 ccagtttcag tgaaaaattt gctggccttt tgacgaaaga ggaaatattt tcctaccccc
     8101 aataaaagca catagaccag aaaaacaggc aagccataac ccatgactaa aaacaagggc
     8161 gcaaataaca gcaagaagag ggtctgaaca aaaatccaaa agactaggga aatgccggtt
     8221 tgacgcttga gatggagctt gatttcctct tctccaacta agagaaagag cttgtctgga
     8281 gcctccatat aggtggcaat tcctccccaa agtaaaagta aaacagacgt aattcctaca
     8341 aacaaaaggg taggccaatg attttcagga aaatgttgta agagttgact gtactggtag
     8401 gctagaaagc ccaacaggac aagcaggaac aagacaaagt ggtcattgag cacatagcgc
     8461 agataacaaa gacactcctt acgaaaggcc tgctttctct ttaaaaacaa gtctttcata
     8521 gatcctcctc tttggtcaga gccaagtaaa tatcattcaa actagcctca ggcatatcaa
     8581 aggcttcacg tagttgcagg agattgcctt tggcacgcac ctctcccttg tgaagaatga
     8641 caaaggcatc acacatcttc tccgccgaat ccagcacgtg ggtactcatg agaatagact
     8701 tgcccttttg cttctccact tccaaaagct gaatcaaatc agaaatagcc agcggatcaa
     8761 gaccaaggaa aggctcatcc acgatgaaaa ggcttggatc caccacaaaa gcacagataa
     8821 tcatgacctt ctgcttcatc ccttttgaaa aatgaacagg gaaccagtct aatttctggt
     8881 ccagacggaa catctttaac aagggctcta ctcgttcgaa agccactttt tgctcaatac
     8941 cgtaagccat agcaaccgtt tcgatatgct ctctgagggt caattcctca tacagactag
     9001 gcgtctcagg aatgtagcca atctgcttgc ggtagctagt cgcatctcct tgcagagtca
     9061 ggccattgat attgatggag ccactataag gtgccaacag accgataatc tcattgatcg
     9121 tcgttgattt cccagcacca ttgagaccaa tcaaaccgac caactgccca ctttcaacag
     9181 taaaggacac atctttcaaa acaggaacat gaacatagcc acctgtcagg tttttaattt
     9241 ctaacatatt ttctccaaat ctggtataat gtagctatat tatatcaaaa tttagtacag
     9301 tagaggtaga ttttatgtca gattgcattt tttgtaaaat catcgcaggg gaaattcctg
     9361 cttcaaaagt atatgaagat gagcaggtcc ttgcctttct tgatatctct caagtaacac
     9421 taggacacac cttggtcgtg ccaaaagaac actatcgcaa tcttttggag atggatgcta
     9481 cgagcgccag ccaactcttt gcccaagtac caaaagtagc tcaaaaagtc atgaaagtca
     9541 ctaaggctgc tggtatgaat atcatttcca actgtgaaga agtcgctggt caaacagttt
     9601 ttcatactca cgttcacctt gtgcctcgct acagtgctga cgatgacctc aagattgatt
     9661 ttatcgccca cgaaccagac tttgacaaac ttgctcaagt cgctgaaacc atcaaaaacg
     9721 cttaaggagt tgctatgaaa ttatccaacc tactgctatt tgcaggagct gcagccggaa
     9781 gttatctggt tacaaaaaat cgccaaacca tcacagatga agtcttgaat accactgacc
     9841 gcgttcaagc tatcaaggac gatgtggata ttatccaaaa cagcctgcaa atcattaacc
     9901 agcaaaaaga acttatcaag gaataccaag aagacttgac ttacaagttt aaggtcttgg
     9961 aaaaggatat ccagactaga ctagctgtga taaaagaaat gcagggaact gaagataagt
    10021 aaaaagagcc ccccggctct tttttaaaac gtaaacaagt tatagtgaat tgaatttaga
    10081 atagcacacc atagtttcta aagcattgtt agagattact ttaaaatcct cttatcaatt
    10141 tgttcatatt ctatttcaat ctattatata tatcccatca actatgcatc ataatttagg
    10201 taactcatac tcaataaaaa tcaaaaagca aactagaaag ctaggcacag actgctcaaa
    10261 acaccgtttt aaggttgtgg atagaactga cgaagtcagc tcaaaacact gttttgaggt
    10321 tgtggataga actgacgaag tcagtaacca tacccatggc aagccgacgc tgacgtggtt
    10381 tgaagaaatt tttgaagagt atcattcacc atttcacaac taaatcgaag actttctgcc
    10441 gtaatgaaaa cacctgaaac agcttggttt cagctgtccg gaaactttaa gacttaggtt
    10501 caaagtttag gtatggaact tcgaaggagg tcgctaccgt ccgtcattac ttaggaaagt
    10561 cttaaaaaat ctataaagta aaaagagccc gacagctctt tttgtttata ctcaatgaaa
    10621 atcaaaaagc aaactaggaa actagccacg ggctgctcaa aacactgttt tgaggttgta
    10681 gatacgactc acatatatac ggcaagccga cgctgacgtg gtttgaagag attttcaaag
    10741 agtattattc tccatcaaag gcatctttaa tatgatcaaa gaagcctttt ttctttggat
    10801 ttactttcaa gtcaccagca gccgcgaatt ctttcaaggc tactttttgg cggtcgttca
    10861 agcctgtcgg tgttacgaca ttaacagtaa cgtattggtc accaactgca ccgccacgaa
    10921 ggctcggtgc ccccttacta cgtaggcgga atttcttacc agtctgagtt ccctctggaa
    10981 taaccaattc aacatcaccg tgaacagttg gaatatctac tgtatcacca agagccgctt
    11041 ggacaaagtt gaggttgaga ttgtagaaga tagtcgttcc ttcacgttca aacttgtcgc
    11101 tagcttccac agaaactact acatacaagt caccataagg tccaccgtta aagcctgctt
    11161 caccttgacc agcgaggcga atttgttgac ctgtttccac accagcaggg attttcacat
    11221 gtacgctatg agcttgtttc tcatgacctg ttccatgaca ggttgtacat ggatatttga
    11281 tttcttttcc ttggccgtga cagacatcac aggttacttg gcgacgcatc ataccaagag
    11341 gagtctgcgt atcgacgtta atgacaccag cgccatgaca gcgtccacaa gtgactggac
    11401 ttgtccctgg cttagcacca gagccattac atgtacgaca gccagcttca cgatgatact
    11461 taacttcctt ctcagttccg aagatagctt cttcaaaggt caaattgaca cgatactgga
    11521 gatcatctcc ttggcgagga gcgtttggat tgcgcgaaga accgcctccg ccgaagaaac
    11581 ttgagaaaat atcctcaaaa ccaccgaagc cacctgcccc attgaaaccg ccgaaaccac
    11641 catctccacc aaaaccacca ttggcgcctg cagcaccata ctggtcatag gcagcacgtt
    11701 tttggtcgtc actcaaagtc tcataggctt cttgaacttc cttgtacttg tcctcagcac
    11761 caggctcctt gttgatatct gggtgatatt ttttggaaag cttacgataa gcctttttga
    11821 tttcgtctgc cgaagcgttt ttggataccc ccagacgatc ataaaattca gtattgttca
    11881 taattcaaga tacaaagggc gtcaaacgga cacagccatc taggagtttt gacgacggac
    11941 gcttatgtcc tagaaaaaac tatctttttg gcacagtccg tagcccgtgt tcagttacga
    12001 acacccttat tcctttctat tgatgttctg aatcgaacca ccatttaggt cggattcaat
    12061 tcctttcttt tatatttagt aagaaattct gaaacccgtg ttcagttacg aacactcttt
    12121 gttcctttct attgatgaga caaaacccaa acaaatgaga ttccgtccct ttttatcgaa
    12181 aaacagaggc tgggttgcaa cctctgcaaa taagtaaatt aactttattt tgattttaaa
    12241 tatcctataa gtacagaaat atttatatat ttttgtctct tcttagtatt tgcctatata
    12301 attccaattg atcataagaa atacaactac tgtccaaatc ataccaatta tgaacggtat
    12361 tacaaattta tatgtttgta tttctaatga tatcatagct gataccatcg ccgatacaaa
    12421 tgcagacaac aatactgaag taacaaaatt ccttaccgct tcatcatttt tgacacaact
    12481 atcatgctca gctaatataa tttctctata tatagtcaaa cattctactg gaatattatc
    12541 tatgaaacct tttgctgctt catagttgtc agcttgatta caaaaatcat tataaacttt
    12601 tcgtgtattt tttagatact catcatccaa tacactcatc ttatttttcc gtaaactctc
    12661 cgtctacgac gtcatcgcct gcgtttcctg ttgcttgtgc gccttctgct ccttcttgag
    12721 cttgttgcgc tgctgcggct tgttcgtaga gtttcacagc aaggccttga gctttttcgt
    12781 tcaacgcttc aagtttcgct ttcatgtcgt ccaagttgtt gtcttcttga gctttcttaa
    12841 ggtcatcaag ggcagcttgg gcagcgtcac gttctgcgtc gaagccttta ccttcagttt
    12901 ccttgattgt cttttcagtc gcaaagattg cttggtctac ttcattacga aggtctactt
    12961 cttctttacg tttcttatca gcttcagcgt ttgcttctgc atctttcatc atgcggtcga
    13021 tttcttcgtc agtcaaacct gagttcgatt ggatgacaat agtttgttct ttttgagttc
    13081 caaggtcttt ggccttaaca gacacgatac cgttcttgtc gatgtcaaat gttacttcga
    13141 tttgaggaat tccacgaggt gcagctggga tatcagtcaa ttggaagcgt ccaagagtct
    13201 tgttatctgc tgccattggg cgttcacctt gaagaacgtg gatatcaacg gctggttggt
    13261 tgtctgctgc tgttgagaag acttgtgatt tagatgttgg gattgtagtg ttgcgatcga
    13321 taagttttgt aaatactcca cccattgttt cgataccaag tgacaatggc gttacatcaa
    13381 gaaggacaac gtccttgaca tcaccagtaa tcacaccacc ttggatagcc gcacccatag
    13441 caactacttc atcagggttt actgatttgt ttggttcttt accagtttca gctttaacag
    13501 cttcaacaac ggcagggata cgagttgaac caccaacaag gataacttcg tcgatttctg
    13561 acaagctcaa acctgcatct gaaagggctt gacgaactgg aacttttgta cgttcaacaa
    13621 ggtcacgagt caaatcgtca aatttcgcac gagtcaaagt catttccaag tgaagaggtc
    13681 cagcctcacc tgcagtgata aatggcaagc tgatttgtgt tgaagttaca ccagaaaggt
    13741 ctttcttcgc tttttcagcc gcatctttca aacgttgcat tgccatcttg tcagtagaca
    13801 agtcgatacc gttttctttc ttgaattctg ctaccaagtg gtcaatgatt ttttggtcaa
    13861 agtcgtcacc accaagtttg ttgtcccctg cagttgacaa tacgtcgaag acaccgtcac
    13921 ccaattcaag gatagagacg tcgaatgtac caccaccaag gtcaaatacc aagatttttt
    13981 cttctttgtc agtcttgtcc aaaccataag caagagctgc tgcagttggt tcgttaacaa
    14041 tacgttctac ttcaagacca gcaattttac cagcgtcttt tgttgcttga cgttgagcgt
    14101 cgttgaagta agccggaact gtgataacag ctttggttac tttctcacca aggtagtctt
    14161 cagcgtagcc tttcaagtat tgaaggatca tagctgagat ttcttgtgga gtgtattctt
    14221 ttccatttgc agaaactttt tcagaagttc ccatcttaga tttgatagag ataactgtat
    14281 ctgggtttgt aactgcttga cgttttgcag catcaccaac gatgatttct ccgtttttga
    14341 atgagactac agatggagtt gtgcggtttc cttctgggtt tgcgatgatt ttgctttcag
    14401 ttccttcaag aactgcaact gctgagtttg ttgtacctaa gtcaataccg ataattttag
    14461 acatgtgttt ttctccttgt tagttaattt tctatttttc tttttgatac tcttcttaag
    14521 tggcgacgcc gtcagagctt gacttcgtca atctctttga ctaaactttg agcctaaggt
    14581 ctcaaaattt gcgcaaatag caccacggcg aagagtatcg tctttggttc gcttcgctca
    14641 ctattacaaa gccaaacata ttttatcttt cttcatagtt tattgtcgtt tcggacaagt
    14701 tttctattat gtaaattgcg acacgaggag tcgaaatcga ttttatttcg acgacgagtt
    14761 agtaaggaag ctaggcaaac gtcatagcga ttgccgtttt ctgacgagtt gctttagcta
    14821 ccgtcagaat tgccgaatcg aacacgccct aagctctgag taaaaaagat agattttctt
    14881 gtgttcatcg aacacttcgt caatctccta tttttactgc gagcttttta cgagctttgt
    14941 atcttagtta tacaccacta ccattgctgg gcgtaggatg cggtcatgga gtttgtagcc
    15001 tttttgaaag acttgggcga tggtatctac tgggtgttca tcgtctgctg ggagagtttg
    15061 gatggccata tggtagttat ggtcaaattc gccatctgct gcgatttctt caattccttc
    15121 ttctttcaaa gcgtgaatca agctttcttg caccatcgcc aagcccttct tcacatcatc
    15181 tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca agagatggta agattgcttt
    15241 tgccaagtcc tggctacgat aacgttgcaa gttttgacgt tcttcattgg cacggcgttg
    15301 gatattttgc atttctgcat gagcgcgaag atatttgttt tcgaactcat ctgcacgttc
    15361 atttgccaag tccaactcag acttttcagg agttgtttct tcagctgttt ccacaacttc
    15421 ctcttcttga acttcttcta cttcttcatt ttttatatct tgggccatgt tcgcctcctt
    15481 taatgatttc aatcttaatg tacttcgtaa tgattactgc tgaggtagcg gtaaaaatct
    15541 gtcaacttca tggtcaaaac acggttgacc acattgattt gattgattag ctgttggtaa
    15601 tccagattaa ctggaccgat aatggctaga attccaactc ctcgataagg aatgaggaac
    15661 ttactactaa tcactgctag gtcagctaaa caggactctt gaccgtctgc aacacgaaca
    15721 ttttgcatct gatcctcacg caacccctca cgaatctcca aggccacctt ttgcggttgg
    15781 tcaaagaact gataggctgc tagattggca aaattcaaga gatggacctt gcccgccatc
    15841 acaatgtttt cgttgaacat ttccttaaag atgtgttcaa agagatcgat gacattatcc
    15901 gttgttgtaa agtaacgctg gataatctgc ggaatctccg tccgaatctt gtagtgaata
    15961 tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc tcttcagttt cagcaaatcc
    16021 tcctgcaaga agttccttgg aatcagaaac tgactagtaa ccgttcgcga ctcgtctagg
    16081 gtaaataccg ccaaggctgt atgttgcccc aaaacaacga tatcaaaggc tgtcaaacgt
    16141 tgcctgctcg gctcaacatc cagtgccact accgtacagc cactcaggtc tgttagtaag
    16201 ttagcagcct cttgcagaat atcctccaat ttgaagaatt cctgatcaaa ggctttgaca
    16261 atctcatata cctcattttc agccagccgg tcaaaatcca gtgagtgttt cacatagtac
    16321 tgaaaaccag caacacttgg catccgaccg cttgaagtat gagccttctc aagcaaccct
    16381 tgtttttcta gttccgccat gtcattacga atggttgcac tgctagagtt aatagactct
    16441 tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa agatgtcaat aatcagattt
    16501 aaaatatcct gctgacgctc tgtaaccatc tcatcactcc tctctgtctg atcaattagc
    16561 actcaatgca tccaagtgct aactcatgat tctattatac acccttagaa gagaatgtca
    16621 agacaaaaac tcaaaaaatt agcactcttt tatcaagagt gctaaaaatc aatctgaaga
    16681 cctagaacct tgctattcat ctactcggta tttccttttt agtctgaaat aaccataaat
    16741 tagataagaa atcagaaaag catataaaac aaaaataaga aagaaagaca tagaaagatc
    16801 ctctctaaac aaactcatac aaacaacaag accacctgag aaagtagctg tacaggaacg
    16861 aagtctagat tgcataactt cccatttgag ccctttactc atacagactt gatcctctgg
    16921 aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctactccta tcaattccca
    16981 acctctatct ctaaaatctt gcagttcatg cttatacttt tttaagaaat ctagaatcat
    17041 agatacggta gatgacatcg tctggttgac attggtcaaa atagaacaaa ccaaaacgac
    17101 tcgttctata cctccaacct ttcaaatgca tctcatgtaa atgttcttct tccttgtcca
    17161 aatcaacaat ggtgaaaatc cgaaattcta ctctgctatt cattgtctta ccccaaaatt
    17221 agaaaacatg cctggcgtta tttattagat aattctttcc acttttgact caatctccaa
    17281 aaaatataag aaatctgaat cgcaaaaact atcaataaaa cccaatctat tatgaaaatc
    17341 aaaaacactt tccaactgaa agaactacct ccagtgacaa actttgagaa aaacggtagt
    17401 agagctaaaa agagaaataa aataggaagc atccgcattg ttaaaatccg tttggcataa
    17461 aaaaatcttt atttaaacga aaatattatg gcaaaattta cgccagtttt tgaacggctg
    17521 atgtagatat tttatacttt caaaatgttt aaatgtgatt atttattttt gaaaaataga
    17581 tcaccagccc gactgaaagt gcttatagaa tgataataag tcgcctgccg aaaacagcga
    17641 aaaatagcgg tgttatgcgg agataatctg acgcgatgcg aaagtatatt gcatacttat
    17701 tttcaacaat ttagcagagt atttttataa gtgtgatata atagaagtat aatttgttct
    17761 gatagtttat tttatggaga agtagatttt tagaatgcgg agggttcaat atggttgagt
    17821 ttataaagtc taagaaagaa atgagtgagg aggatattaa agcaaatttc atcactcctg
    17881 ctattgtatc caaaggatgg aaaaatggtg agcatatcgc ttacgaagaa tacttcactg
    17941 atggtcgaat tgaagttaga ggagataagg ctcatcgtaa agaaggaaaa aaatcagact
    18001 attcactgta ttaccaattt ggaactcgaa ttgcaattgt tgaggcaaag gataataaac
    18061 acagcgttcg agcaggatta caacaagcta ttgaatatgg agagatttta gatgttccat
    18121 ttgtttattc ttcgaatggt gatggcttta ttgaacacga ccgtatcacg agagaagaac
    18181 gtgagctgga gttagacgaa ttccctactc gtgaagaatt attttctcgt atgacgaagg
    18241 aaaaaggatt gacgtacgaa attacagaag ctatctcaac tccatactat acagacgcct
    18301 tctcaatgaa aacgccacgc tattatcagc aaatagctat caaccgtact attgaaacag
    18361 ttgccagagg acaaaaacga gtaatgtttg tgatggcaac aggaacgggg aaaacgttca
    18421 tggcttttca aattattcat cgccttcgaa aagctggttt ggctaaacga gttttattct
    18481 tagcggatag aaacatctta gtagaccaaa cgatggctga agactttagg ccattcgaaa
    18541 aggtaatgac gaaaattaca ccaaaacttt tgactgctcc tgaaaaatta aattcttttg
    18601 aaatttatct agggctttat cagcaactaa ctggtgaaga tggaactgaa acacattatc
    18661 aaaaatttga caaagacttc tttgatttaa tcgtaattga tgaagcgcac cgtggttcag
    18721 ctaaggaaaa cagtaactgg cgtaagataa ttgattattt cagttctgcg acacagattg
    18781 ggatgaccgc tactcctaaa gaaaccaaga atgcttccaa tacggaatac tttggtgagc
    18841 caatctatac ttatagttta aaacagggaa tcgaggatgg ttttttggct ccatatcgtg
    18901 ttatgagagt taatttagat gtagatgtgg atggttatcg tccagaaact ggaaaagttg
    18961 atgctaacgg acaattaata gaagataggt actacggcag gaaagatttt gataaaacca
    19021 ttgtcattga tgatagaacg caaagagttg ccaagtttgt ttctgattat atgaagcaaa
    19081 acaatgcacg atttgataaa acaattgttt tttgtgttga tattgaccat gccgagcgaa
    19141 tgcgtgctgc acttgtaaaa gagaatctag acttagtcca agaagactat cgttatgtca
    19201 tgcaagtaac tggtgacaac gctgaaggaa aagctcaact ggataacttt atggatgtca
    19261 attctaattt tcccgctatt gtaacaacgt ctaaattatt aacgacagga gttaatgcta
    19321 aaacatgtcg tttgattgtt ttagactcta atatccaatc catgactgaa tttaaacaaa
    19381 ttattggtcg tggcacacgt ctttatcctc aaaaggggaa agaatttttt acgattattg
    19441 attttcgaaa tgttaccaat ttgtttgctg accctgattt tgatggtgat ccagtgaagg
    19501 tgctggaaac aggtgcgaaa acagtcagtg gttctacgcc cggtttcgta agtgaggaag
    19561 gtgacccagt agaaaaatat atcgttacag acaagcaggt taccattctt aattctactg
    19621 ttcaagtatt ggatgaaaac gggaaactga ttaccgaaag cctgaccgac tacactcgga
    19681 agaatatctt aggtagctac gccactttga acgattttat cacagtttgg catacggcgg
    19741 ataaaaagaa gcttatctta gacgaacttt ataaaaaagg agtttatcta gatgctattc
    19801 gagagtcgga gggaatatca gaacaagaaa tcgatgattt tgatttactc ctaaaacttg
    19861 cctatggtca aaaagaatta accaaaacgg aacgtatcaa taagctcaaa caaagcggat
    19921 atttatataa atatagtgag gaagcgcgtg ctgttttgga aattttactg aacaaataca
    19981 tggataaagg tattggagaa ctcgaaagca ttgaaacatt aaaacttcca gaatttcaga
    20041 tatatggtgg aaccttcaaa atcatcaata cttattttgg agataaaaaa cgatatttac
    20101 aagcaattaa agaattggag caagagctat ttacagtagc ttaatgaaag gaaagtatgt
    20161 caattacatc atttgtaaaa agaattcaag atatcactcg aaacgatgct ggtgttaatg
    20221 gtgatgctca acgtattgag caaatgtctt ggttattatt cttaaaaatt tatgatagcc
    20281 gtgaaatggt ttgggaatta gaagaagacg agtatgagtc aattatccca gaggaattaa
    20341 aatggcgaaa ttgggctcat gctcaaaatg gggaacgggt attgacaggc gatgaattac
    20401 ttgattttgt caataacaag ttattcaaag agttgaaaga gcttgaaata acttcaaata
    20461 tgcctattcg aaaaacgatt gttaaatcag cttttgaaga tgcgaacaac tatatgaaaa
    20521 atggcgtctt gttacgccaa gtcatcaatg ctattgatga agttgatttc aatagccctg
    20581 aagatcgtca ttcgtttaat gatatttacg aaaaaattct taaagatatt caaaatgctg
    20641 ggaactcagg agaattttat acgccacgtg cagcgactga ttttattgcc gaagttcttg
    20701 acccaaaact tggagaatca atggcagacc ttgcttgcgg aacaggaggc ttcttgactt
    20761 cgactctgaa ccgtttaagt agtcaacgta aaactagtga agataccaaa aaatataata
    20821 cagctgtttt tggtattgaa aagaaagcat ttcctcatct tttagcagtt acaaatctgt
    20881 ttcttcacga aattgatgac cctaaaattg ttcatggaaa tactttggag aaaaatgttc
    20941 gtgaatatac gaatgatgaa aaatttgaca ttattatgat gaatccacct tttggagggt
    21001 cagaattaga aacaataaaa aataactttc cagcagaatt acggagttct gaaacagctg
    21061 atttatttat ggctgtcatt atgtatcgtt tgaaagaaaa tggtcgtgtt ggagttattt
    21121 tacctgatgg ttttctattt ggtgaaggtg taaaaactcg cttgaaacaa aaactggtag
    21181 atgagttcaa cttgcatacg attattaggt tgcctcatag tgtctttgca ccgtatacag
    21241 gaatccatac gaacattctt ttctttgata aaacaaagaa aacagaagaa acttggtttt
    21301 atcgtttaga tatgccagat ggttataaaa atttctcgaa aactaagccg atgaagtcag
    21361 aacacttcaa tcctgttcgt gactggtggg aaaatcgtga agagattctg gaaggtaagt
    21421 tctacaaatc taaatcattt acacctagtg aattggctga gttgaattat aatttagacc
    21481 agtgtggttt tccaaaagag gaagaggaaa tcttaaatcc ctttgagttg attcagaatt
    21541 atcaagcgga aagagcaact ttaaatcata agattgataa tgtattagct gatattttgc
    21601 agttgttgga ggacaaataa tgacaccaga acaacttaaa gcaagtattc tccaaagagc
    21661 gatggaaggg aaattagtgc cgcaaaatcc caatgacgaa cctgcaagtg aattattaaa
    21721 gagaattaaa gctgaaaaag aaaaacttat cagtgaagga aaaatcaaac gagataaaaa
    21781 ggaaactgag atatttcgtg gtgatgatg
//
LOCUS       DAVMCG010000032        21724 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVMCG010000032 DAVMCG010000000
VERSION     DAVMCG010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.033"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..234)
                     /locus_tag="VYP66_001465"
     CDS             complement(<1..234)
                     /locus_tag="VYP66_001465"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1851007.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIF"
     gene            complement(238..456)
                     /locus_tag="VYP66_001466"
     CDS             complement(238..456)
                     /locus_tag="VYP66_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1851008.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(747..980)
                     /locus_tag="VYP66_001467"
     CDS             complement(747..980)
                     /locus_tag="VYP66_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HEV1851009.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCN"
     gene            complement(1194..2825)
                     /gene="rlmD"
                     /locus_tag="VYP66_001468"
     CDS             complement(1194..2825)
                     /gene="rlmD"
                     /locus_tag="VYP66_001468"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1851010.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2899..3873)
                     /locus_tag="VYP66_001469"
     CDS             complement(2899..3873)
                     /locus_tag="VYP66_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1851011.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVYAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3947..4561)
                     /gene="pmp23"
                     /locus_tag="VYP66_001470"
     CDS             complement(3947..4561)
                     /gene="pmp23"
                     /locus_tag="VYP66_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1851012.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4561..5535)
                     /locus_tag="VYP66_001471"
     CDS             complement(4561..5535)
                     /locus_tag="VYP66_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1851013.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5543..6799)
                     /locus_tag="VYP66_001472"
     CDS             complement(5543..6799)
                     /locus_tag="VYP66_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1851014.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6861..7292)
                     /locus_tag="VYP66_001473"
     CDS             complement(6861..7292)
                     /locus_tag="VYP66_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851015.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7294..7893)
                     /locus_tag="VYP66_001474"
     CDS             complement(7294..7893)
                     /locus_tag="VYP66_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1851016.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7880..8719)
                     /gene="prmC"
                     /locus_tag="VYP66_001475"
     CDS             complement(7880..8719)
                     /gene="prmC"
                     /locus_tag="VYP66_001475"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1851017.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(8719..9798)
                     /gene="prfA"
                     /locus_tag="VYP66_001476"
     CDS             complement(8719..9798)
                     /gene="prfA"
                     /locus_tag="VYP66_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1851018.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9808..10287)
                     /locus_tag="VYP66_001477"
     CDS             complement(9808..10287)
                     /locus_tag="VYP66_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851019.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10277..10876)
                     /locus_tag="VYP66_001478"
     CDS             complement(10277..10876)
                     /locus_tag="VYP66_001478"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1851020.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALTIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10999..11181
                     /locus_tag="VYP66_001479"
     CDS             10999..11181
                     /locus_tag="VYP66_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1851021.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11318..12691
                     /gene="mnmE"
                     /locus_tag="VYP66_001480"
     CDS             11318..12691
                     /gene="mnmE"
                     /locus_tag="VYP66_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1851022.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEEVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12738..13673)
                     /gene="dapA"
                     /locus_tag="VYP66_001481"
     CDS             complement(12738..13673)
                     /gene="dapA"
                     /locus_tag="VYP66_001481"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1851023.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     YPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13729..14805)
                     /locus_tag="VYP66_001482"
     CDS             complement(13729..14805)
                     /locus_tag="VYP66_001482"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1851024.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15391..15463)
                     /locus_tag="VYP66_001483"
     tRNA            complement(15391..15463)
                     /locus_tag="VYP66_001483"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15428..15430),aa:Thr,seq:ggt)
     gene            complement(15563..16072)
                     /locus_tag="VYP66_001484"
     CDS             complement(15563..16072)
                     /locus_tag="VYP66_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1851025.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(16070..16166)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16195..16626
                     /locus_tag="VYP66_001485"
     CDS             16195..16626
                     /locus_tag="VYP66_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1851026.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            16708..17085
                     /gene="mscL"
                     /locus_tag="VYP66_001486"
     CDS             16708..17085
                     /gene="mscL"
                     /locus_tag="VYP66_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1851027.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKTTELEVLQEIKALLEKK"
     gene            complement(17127..18221)
                     /gene="hemH"
                     /locus_tag="VYP66_001487"
     CDS             complement(17127..18221)
                     /gene="hemH"
                     /locus_tag="VYP66_001487"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1851028.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVSISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRGNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            18376..19599
                     /gene="pepT"
                     /locus_tag="VYP66_001488"
     CDS             18376..19599
                     /gene="pepT"
                     /locus_tag="VYP66_001488"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1851029.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTTIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(19635..20264)
                     /locus_tag="VYP66_001489"
     CDS             complement(19635..20264)
                     /locus_tag="VYP66_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851030.1"
                     /translation="MNNANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            20229..20450
                     /locus_tag="VYP66_001490"
     CDS             20229..20450
                     /locus_tag="VYP66_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851031.1"
                     /translation="MDLFQELICIVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHRFNIL"
     gene            complement(20527..21069)
                     /locus_tag="VYP66_001491"
                     /pseudo
     CDS             complement(20527..21069)
                     /locus_tag="VYP66_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(21173..21724)
                     /locus_tag="VYP66_001492"
                     /pseudo
     CDS             complement(21173..21724)
                     /locus_tag="VYP66_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6294 a         4525 c         3999 g         6906 t
ORIGIN      
        1 aaaaatttgt ttgctaatat ctctttcttc tgattttgtt tcaaggatta ttgctacatc
       61 attcatattt ttaggtaaat accaaccatc tggcttatct gaatatccct tgaagcctaa
      121 ttgattaaaa gtagttattt gaccagtacc ttgattgatg ttttcttcaa cttcattaaa
      181 gcctaatact tctcttgcat aatccctaac ttgatcttct gtcctcaaag tcattttcta
      241 ttcctcatca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      301 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      361 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      421 taactgtatc cataatggtt tatagttaag tgccataata tccctctttt tttcttcatt
      481 agatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      541 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      601 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      661 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      721 aaagaatctt taaattcatt ggtatgctaa ttacaatatc cattattaaa atggatacta
      781 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      841 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      901 tcaagcacct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
      961 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1021 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaatgatc ctatcaatct
     1081 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1141 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1201 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1261 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1321 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1381 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaattcat ctcatccagc
     1441 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1501 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1561 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1621 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1681 ggatcaacca agataacggt tggttgaatc ccatctttaa gccaattctt catagcattt
     1741 tcagctgtgt cacagacata atgggcgttt gaaatattgt tcagctgagc atttttttta
     1801 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1861 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1921 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     1981 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2041 tgaccataaa gagtgcgcca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2101 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2161 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2221 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2281 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2341 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2401 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2461 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2521 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2581 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tggtgactgg
     2641 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2701 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2761 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2821 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg gttaccatcc
     2881 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     2941 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3001 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3061 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3121 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3181 ttcaacaatc ttgcggatat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3241 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3301 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3361 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3421 actctcacct gtaactggaa tgggtgctgc tacagtgatt ttggcgtgtt ccacacccaa
     3481 agttacggct gcatttcggt acatatcctg agttacctta gtgatgtttt caggtgtttc
     3541 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3601 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3661 cttaagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3721 ttggtcttca gatagggaag aacctaggac atattcaggt tggacatagg tttcatcgat
     3781 aactttttga acatctgttg ctgcatagac gctattcata gctgttactg cccacaagat
     3841 cgcagcgcta gtcagaaaga gtttctttct catagggaat ttcctccttt acttctttag
     3901 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     3961 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4021 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatggga tgaatataac
     4081 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4141 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4201 caaaattata ggcttgaaca gctgtccaga tatctacacc cttcttctgc gccagataga
     4261 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4321 tggtggaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4381 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaata
     4441 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4501 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4561 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcgtt
     4621 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4681 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4741 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4801 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4861 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4921 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     4981 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5041 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5101 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5161 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5221 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5281 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5341 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5401 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5461 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5521 aatataaata tccataaaag ttttagtcct cgtataatgg gaaggcatct gtcaattctt
     5581 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5641 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5701 ctgctccgat acgaatccca cttgtcttga atggcgacaa ggtttcgtaa gggattgaat
     5761 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5821 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5881 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     5941 catattcctt gaaggctgga tccaaaactt ctttgaaaga aactgcttta gccgccacaa
     6001 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6061 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6121 ttgttgttgt gatatgagcg tatggaactg ggcttggatg aaggccagcc gcaaccaaac
     6181 cagcgatatg ggccatgtcc accatgagct tcgcaccgac agcatctgcg atttcacgga
     6241 attttgaaaa atcgataatt tgagaatatg ctgaagcacc agctacaatc agttttggtt
     6301 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6361 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6421 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6481 tgtaagccgc acagttagct tggcttcctg aatgtggttg gacattggca aatttagcac
     6541 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6601 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6661 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6721 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6781 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6841 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6901 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     6961 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7021 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7081 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7141 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7201 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7261 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7321 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7381 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7441 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7501 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7561 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7621 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7681 ttgtagataa gctggctgat tcttagaaaa gtgcaagata tcctctaaag aggcaacatt
     7741 gagattgagc gccttgtctc taggacgacg tttgagctgg taaacatggt caactgcttt
     7801 ttcgtctaag gccttggcaa aaagaccata aaccgtctct gtaggcagaa tgacagctcc
     7861 accattttcc aactcttgtc taatcctgtc catcatcaac cacgaccatc ctatcttgac
     7921 caaattggtc cttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     7981 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tctttgagat
     8041 agtcttttgc atcttccgca attctacggt aaatagctag gccatcctcg tctgcaaaga
     8101 gagctagatg aggctccgaa tacaagacat tcaagcctac ctctgactca tcttcacgag
     8161 agatataggg tggattggaa acaattatat catatttttc agaaatttct gtaaaacagt
     8221 cagatttttt aaaaaatatt tgaagatttt gatttttagc attttcgcta gctaaatcta
     8281 aagcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8341 cgagagcaat agctccacta cctgttccaa tatccagaac tgaaagattc gtctcaagat
     8401 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8461 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8521 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8581 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8641 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8701 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8761 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8821 ggtcaagccg atacggtggt ctgtgacacg gttttgtggg aagttataag ttcggatccg
     8881 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     8941 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcgcggtt
     9001 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9061 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcaccagagg cgtgatagat
     9121 gtcgacacga aggtcttttg gatcaatgtc gtattcaacc tcttcaactt ctggcataac
     9181 aagaactgtc gctgtcgaag tatgaacacg gccttggctt tctgtcacag gaacacgttg
     9241 cacacggtgg gcacctgatt catacttaag cttagagtat acagactgac ctgaaaccat
     9301 agcaaccact tctttaaaac caccgacacc attcatagag gcttccatga cttcaaagcg
     9361 ccaaccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9421 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9481 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9541 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9601 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9661 ggtgtcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9721 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9781 ttgatcatag atgttcattt tttctcctta tttctcaatt gttaaatcat agattgctac
     9841 tacttcattc tcggatattt ccccagtttc tttaaatcca taactgagat aacaaaatct
     9901 tgcctgttca ttttctggtt cataagacaa ccaaagttta ttgcttaaac ctgctggcgc
     9961 tgttcgaaca tagtctagta ctttatccat aattggttta aaatatcctt gattttgaaa
    10021 attcttatca atcataaaac gaaatagtaa ataatttcca ctactaatta cgatcttttt
    10081 atcataagct atcatcacaa aacctataat tacatcatta tcataaactg ccaatggagc
    10141 tacaaaatct ccatttttag tgtagacgta tgcttcagct aaactaattg cgttggttgc
    10201 aatgaattgt ttttgatatt ccttgacatc caaatttaaa acatcaaaat aattttccat
    10261 tgtaacatct cttagttcaa ttgtcatagt tttgctcctt gttagaggtt atcattggcg
    10321 caaaataatg tttacggcaa accgaaatat aggtttcatt accaccaatc tggatctgtt
    10381 ctccatcgta aacgggcagt ccatcctgtg ttcgcaacac catggtcgcc tttttcttgc
    10441 aatactgaca gatggtcttg atttcgtcaa tcttgtctgc taaaagcaag agatatttgg
    10501 aaccttcgaa caattcattg cgaaagtcat ttttcaagcc aaaagccatg acgggtatgt
    10561 ctaactcgtc cacaacacga gctaggtcgt aaacatggtg gcgtttgaga aactgggctt
    10621 catcgaccaa aacacagtaa ggtttttctg gtaggtctcg gatatagcca aagatatccg
    10681 ttgtttcctc aatcgtaagg gcagggcgtt tcatgccaat tcgactcgac acatagccaa
    10741 caccgtcacg cgtatccaga gccgaagtca taatgacaac accttttcct tgctcctcgt
    10801 agttataggc cactttgaga atctcaatcg ttttaccaga gttcatggtc ccataacgat
    10861 aatacaactg tgccatgttt cttgcttcac gtccatttct aaatttttgc tacattctag
    10921 tatatcataa ttttcttaag ctttaaacgg caaaatgtgg taaaatggaa gaaatcaaaa
    10981 ctagtggagg aagctattat gccatttgta cgcatcgatt tatttgaagg acgcacgctc
    11041 gagcaaaaga aagctcttgc taaggaagta acggaagcag ttgtccgcaa cactggagcc
    11101 cctcaatctg ctgtccatgt catcatcaac gacatgccag aaggaactta cttcccacaa
    11161 ggggaaatgc gtactaaata agctagctta agcagaattg cttaggcttt ttcaatctcc
    11221 aagtagcatt cattgaagaa atatcctaaa tttgttacaa tttgaaaaga aacttggaga
    11281 atttccaaga aaatagctat taattaaagg aaacattatg attacacgtg aatttgatac
    11341 catcgctgct atctctactc cactaggtga aggggctatt ggtattgtcc gcctgagcgg
    11401 aacagacagt tttgctattg cgcaaaagat ttttaaagga aaagacttga acaaggttgc
    11461 cagccacact ctcaactacg gtcacattat tgatcctctg actggtaaag tcatggacga
    11521 ggtcatggta ggagccatga aatctccaaa aaccttcact cgtgaagata ttatcgagat
    11581 taacacccac ggtgggattg cggtgaccaa tgagattctc cagctagcta tccgtgaagg
    11641 agctcgattg gctgaacctg gtgaatttac caaacgtgcc ttcctaaacg gtcgcgtaga
    11701 tttgacacag gctgaggcag tgatggacat catccgtgcc aagactgaca aggccatgaa
    11761 cattgcagtt aagcaattag acggctccct ttctgacctc attaacaata cccgtcaaga
    11821 aatcctcaat acacttgccc aagttgaggt caatatcgac tatcctgaat atgatgatgt
    11881 tgaggaagct actactgctg ttgtccgtga gaagactatg gagtttgagc aattgctaac
    11941 caagctcctt aggacagccc gtcgcggcaa aatccttcgt gaaggaattt caacggctat
    12001 cattggacgt cccaacgttg ggaaatcaag ccttctcaac aacctcttgc gtgaggacaa
    12061 ggctatcgta acagatatcg ctgggacaac acgagatgtc atcgaagagt acgtcaacat
    12121 caatggtgta cctctcaaat tgattgatac agccggtatt cgtgaaacag atgacatagt
    12181 ggaacaaatc ggtgttgagc gttcgaaaaa agccctcaag gaagccgact tggttctact
    12241 agtgctaaat gccagtgaac cactgactgc gcaagacaga caacttcttg aaattagcca
    12301 agataccaat cgcattattc tacttaataa aaccgacctg ccagaaacga ttgaaacttc
    12361 gaaactacct gaagaggtta tccgtatttc agtccttaaa aaccaaaaca tcgacaagat
    12421 tgaagagcga atcaacaacc tcttctttga aaatgctggc ttggtcgagc aagatgctac
    12481 ctacttgtca aacgcccgtc acatttccct gattgaaaaa gcagttgaaa gcctacaagc
    12541 cgttaatcaa ggtcttgagc tggggatgcc agttgatttg cttcaagttg acttgactcg
    12601 tacttgggaa atcctcggag aaatcactgg ggatgctgct ccagatgaac ttattaccca
    12661 actctttagc caattctgtt taggaaaata agaaaaatcc atgatccttc attcggtcat
    12721 ggattttatt gtctttatta gtaatctggt cttaagaccc ctgttacagt tgccttagtt
    12781 gcttcgtagt cgccatctac gacaaccttg ataatgcgtt tagcatcttc ttctggtgct
    12841 ggaacaagag gtagacgagt gggtccagct tcaaatccca tatagttaag aactgcctta
    12901 actggagcag gacttggata agagaagaga gcattaacct taggaatgaa tttacgctga
    12961 attgctgcgg ctttcttcat atcgctttct gcaatggcag taaacatctc gtgcatttca
    13021 tccccatttg tatgagaggc aacagaaata accccatccg ccccaaggtt catggcatgg
    13081 aaagcatctc catcctcacc tgtataaatc aagaactctt caggcttgtg ctcaatcaaa
    13141 taagccatat tagccaagct agtacattct ttgacaccga taatatttgg atagtcagcc
    13201 aagcgaagca tggtttctgg agtcaattcg acaactacac gccctggaat gttatagata
    13261 ataattggta ggtcagaagc atctgcaata gccttaaagt gctgatacat cccttcttga
    13321 gaaggtttgt tgtagtaagg aacaatagca agcccagctg cgaaaccacc aaattccgct
    13381 acttctttga caaactcaat agagtcacgc gtatcattag tacctacacc cgcaatcaaa
    13441 ggaacgcgtc cattgacaac cttttgtaca gccgcaaaca actccaactc ctcatcgtgg
    13501 gtcaaagttg gactctcagc agtcgttcct gcgagaagaa ttccatccgt atgatgggcc
    13561 aataaatgct caatcaaggc tggaatagca tcaaagttaa tggaaccatc ctcatggaag
    13621 ggggtaataa aggctgtaat gattttacat tcttttaaat cttgataaga cacgaaaaca
    13681 cctctctatt tcaaagaagg agttcatctg aactcctaaa cgatatgact attttaattc
    13741 aaatttcaat tcggctgttg gacgaaccaa tccacgttca tgaagagttt cagcaatctg
    13801 aactgagttc caagcagcac ctttgagaag gttatctgaa acaacccaca tgtgaattcc
    13861 tttttctgca tccaagtctt tacggatacg accaacaaag gtatcacgcg aaccaactgc
    13921 attgatggct tgaggataga tttgatgagc tacatcatct tcaagaacag cacctgggaa
    13981 ggctgcgata gctgctttta cttcttcgat tggagccact tcttttgttt cgatataaac
    14041 agactcagag tgagctgaca agactggaat acgcacacat gttgcagata ctgcaatgct
    14101 atcatcttcc ataattttct tagtttcctt ggtcatcttc atctcttcgt acgtgtaatc
    14161 attatcagtg aaaacatcaa tttgtggaag agcgttaaag gcgataggat aatgtttctt
    14221 gtcaccacct gaaggcaaaa tttccgcatg caaatcacat ggtttcacac catcattcaa
    14281 gacttcacga agttcacgtt gtgtctcaag aattgctccc ataccagcac ctgaaacggc
    14341 ttgataagtt gaaacaatga tacggtccaa gccccatttt tggcgaaccg gctcaagagc
    14401 caccatcatt tggattgttg aacaattagg gcaggcaatg attccgttgt gagcatcaag
    14461 tgcatgagca ttgacctctg gaacaaccaa aggaacatct ggattttgac ggaaataaga
    14521 tgtattatct actactacca cgccagcttt tactgcgtat ggtgcatact tagctgatgt
    14581 agaaccacct gctgaaaaga gagcaatatc aactccttca aaagctgttt cagtcgtttc
    14641 ttcaatcgta atatcttgat ctttaaattt caatgactta cctgctgaac gtgcagaagc
    14701 aaggtaacgg attttatcga ttggaagtgt tgattcttcc aacattttta tcatctgagc
    14761 accgacagca cctgtcgcgc cgactacagc aactgtatat cccataaata acctctttcg
    14821 gaattttcta aaaatttcta taatagaagt attatactac tttttccatg aattgcaaag
    14881 ctttttcatc attttttgga aaataaaaat ccccaatcgc tagactaggg attaagaggc
    14941 atcttcatgt gatgagcagg ttcacacaac tcatcaaggt ccgctcctgc gttatgacct
    15001 ccttatgctc aatagtagcc cgaagactac ctatcgactc atcgcatcta ctattctact
    15061 aaagagaatg acttttgtca acagacgaaa ctctttatac tcttcgaaaa tctcttcaaa
    15121 cttcgtcagc gtcgccttgc cgtatgtatg gttactgact tcgtcagttt catctacaac
    15181 ctcaaaaaca tgttttgagc tgacttcgtc agttctatct acaacctcaa agcagtgctt
    15241 tgagcaacct gcggctagtt tcctagttta ctctttgatt ttcattgagt attagtttta
    15301 tttacacagg tgcataagaa atatattgga aaaattgggg gcagacataa caaaaaccct
    15361 tgtaaatcaa gggcttttct gtctatttaa tgctaattgc cgggattgaa ccggcgacct
    15421 catccttacc atggatgcgc tctgccaact gagctaaatc agcttactta agaagtatac
    15481 tataatcaga aaaacttgtc aagtttcctt agaaattttc cataggaaaa agccaggtaa
    15541 gaactaccta gcttatcttc ttctatttac ttaaatcaat tcgacgacca attttaccaa
    15601 taataatcgc tccaataatc aatgaagcaa attcaccgat tcctgttgta aaccaagtaa
    15661 ggaagaatgg taattctgct acaatattta actctgcagc gatagtaaac atggaaattg
    15721 aaaagaggat tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct
    15781 tgctatattt tgcaaaaagc caaacaccta aactgaggaa tactaaggtt gaaccaccac
    15841 caacaaagac atctagcagt ccgaagctaa agaaattagc aatcatacaa ccgatggtaa
    15901 ctccgatgat gtacttagga ttgtaaaaag ccataaagtt catcatttct gaaatacgaa
    15961 actgataagc accatagctg atggcattta ggggcggtgt gacagtcaaa acgacgtaga
    16021 tagcagcgac gattgcaata tctgcaacat cacgaatagt taattttttc atcttttctc
    16081 ctttggcggt tatccgcgtg taatatgctt ggtgaaagaa gctaagcacc aagggttgat
    16141 tcattcaacc ttactagtat agcacaatag cctgctttat gctatactta aagcatgaaa
    16201 aaacctattc aaaaattttt taacaatgaa atcttagcct atctcttttt tggccttgcg
    16261 acaactctag tttcgattct ctcacgacta gtcatttatc aactaagtca tcaggaactc
    16321 cttgctacgg ccttggcaaa tattatcggt atcttatttg cctttatcac aaatgatacg
    16381 attgtattta agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt ttctcttgct
    16441 cgcctttcta cttttctgtt agacttgttt ttaacttttc tctttgtaac ccaatttcct
    16501 cacatcatag ggcaattcgt aactgaaaac attgataaga taaatgctat tgaaacaata
    16561 attgcacaaa tattcattat tatcatcaat tatatcttga gcaaggtcta tatttttaga
    16621 aaataatgct ccatttatga gccttttaat tgccttctat aatgatttag gatacaatga
    16681 aacacgaaac attgaaagga aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga
    16741 ggaaatgtta ttgaccttgc tgtcggtgtt gtcattgcct ctgcttttgg tgctatcgtt
    16801 acttcacttg taaacgacat tatcactcct cttattttaa atcccgcttt gaaagctgct
    16861 aaagtcgaac gtatcgctca actttcttgg catggagtcg gctatggtaa ctttttaagt
    16921 gctattatca attttatctt tgtgggtacc gccctcttct ttattatcaa gggcattgaa
    16981 aaagcacaga aactgactgg cataaagaaa gaaaaaactg ccgaaaaaaa aacaaccgaa
    17041 ttggaagtcc ttcaagaaat aaaagctctc cttgagaaaa aataatcgat taaaaggatc
    17101 tagcgcaaag ctaaatcctt ttttctttac tctttgggta acttgcctgc tttttcaagc
    17161 atttttttga taagataagg catcttaaca ttctcccgcc cttttttctc aatcagtttt
    17221 ttcacaaatt ctggcatttg taaatcttca gattcagcta aaatgttttt cgtctcgtct
    17281 gaaggaacta actcatcaaa ggtctcttct tctgggagaa attccttaaa ctcttgattt
    17341 tcattgcctc taactgtatt gaccaaagca tcaatcaaac gagaatctgt atttggcatt
    17401 ggtggacgat ggtagtttac cccaaattcc tggcataagt cataacattc tacatcattg
    17461 tcaaacaaga cctcaatatg ctcactgatg aaactaatag atacaaaaat ataatggtct
    17521 ggatgttctg tctgttctct gagatactcc aaaacatctg gtttaatcca tggaatacca
    17581 atatcactct cactctgcca agtgttggta tattgttctg aactcaagcc cagtttttca
    17641 gcgactagct tgctattttc gaaaatttgg tctatataag gatcaccaaa gtccaaggca
    17701 aaaatgggca cactatgggc tgaaaagatg actttaaagc tgtcttgctt tacttcttct
    17761 tttaaaatct tagcaatttc atctgcccaa tagtttaaga gcgcttcttc ctgataccag
    17821 tccttaatga ccaaaaattg aatttgtttg ctttctaaaa atttttcata gcccatgaca
    17881 gagtagaaag aataatgggg ctccaaaatc aagcaaatac actgttcaat tccgtctgct
    17941 tccatttgac cgatcacatc tggaataaag ggactggaaa acttattagc aaagtagaca
    18001 ctgtattcat tccccagcct agcttctacc aaggcaacct cttgacgggt aattttttgc
    18061 agaggcgtgc ctccaattcg tacataatta tcatagagag tctgaatctc gtggtcttgg
    18121 ggtctcaccc cacgacgaat atttgtgaaa aaatcagcta caccttcaaa ggtaatctct
    18181 tctggtgaac cgaaggtcat cattaaaatt gcttttttca tgactgcttc cttgtgatgt
    18241 ttttatcaag tttattttat cattaattca tcgataagta aacgctaaca tagggacatt
    18301 ctcaatcttc tgtcttttgt ttttctcttc tttctatgat acaatggaaa aaataaattc
    18361 aaaaggagtt tttttatgac ttatccaaat ctcttggacc gcttcttaac ctacgttaag
    18421 gtcaacacgc gctctgatga acactctact actactccaa gtacacagag tcaggttgac
    18481 ttcgcaacaa atgtcctaat tcctgaaatg aaacgtgttg gactgcaaaa tgtttactat
    18541 ctaccgaatg gttttgctat tggaaccttg ccagccaacg atccgtcttt aacacgtaag
    18601 attggtttta tatcgcacat ggatactgct gattttaatg ctgaaggagt caatccacag
    18661 gtaattgaaa actacgatgg tggtgtgatt gaactaggga attctggttt caaactcgat
    18721 ccagctgact tcaagagtct tgaaaaatat ccaggacaaa cgctcatcac aacagatgga
    18781 acaagcttgc taggtgctga tgacaagtca ggaattgctg aaattatgac aaccattgaa
    18841 tatctaactg ctcatcctga aattaagcac tgtgagattc gtgttggttt tggtccagat
    18901 gaagaaatcg gtgttggtgc caataaattt gatgcagaag attttgatgt ggattttgcc
    18961 tacactgttg atggtggtcc actaggtgaa cttcagtacg agactttctc agccgctggt
    19021 gctgaattgc atttccaagg ccgtaatgtc caccctggta ctgccaaagg gcagatggtc
    19081 aatgcccttc agctagcaat tgattttcat aatcaacttc cagaaaatga ccgacctgag
    19141 ttaactgaag gttaccaagg tttttaccat ctaatggatg tgacaggtag tgttgaggag
    19201 gtgcgtgcaa gctacatcat tcgtgatttt gaaaaagatg cctttgaagc gcgtaaagca
    19261 tccatgcaat ctatcgctga taagatgaat gaagaacttg ggagcgaccg tgtcactctc
    19321 aacttgacag accagtacta caatatgaaa gaagtcattg aaaaagatat gactccaatt
    19381 accattgcta aagccgttat ggaagatcta ggtatcacgc ctattatcga accaatccgg
    19441 ggtggaacag acggctctaa gatttccttt atgggaatcc caactccgaa tatctttgca
    19501 ggtggcgaaa atatgcacgg acgttttgaa tacgttagcc ttcagactat ggaacgtgca
    19561 gttgatacca tcattggcat cgtagcttat aaaggctaaa aagacgaggt agctcagcta
    19621 cttcgccttt ctttttattc tactggtttt tcttgatttc cagtagttgt agaagattct
    19681 gttgtttcat tttctgaagt tgattcagca ggtttagaat ctcttgtatt gcttggtttg
    19741 ttttcgtcgc tagcagtttc aatgttagat tctgcagttg cgtttggttg gttctcagca
    19801 ctggtgttat cactatttgc ttcagcattt cttgctggac ttgtttcttc acttgcgcta
    19861 gcttttgact ggatttgatg attcaaaact agaatagctt ttgtcgattc aagtaaagct
    19921 gttttgtctt tactcttagc agaaagttga tctaataatg catccacctt atcaaagtcc
    19981 gcatcagatc cattattact ttctaaataa gagtgaagcg acatgagaat atcgtagagt
    20041 ttttgataga gtacaagtgt ctgagaatct tgctcagcat tttccttttc ttgttgaagg
    20101 gcgctagcga tacgagtcaa aacatctttt acctgactgt ttacttcatc caagtctgca
    20161 tcagccttgt ttgtggcagc ttttagattt tctacttctt ctgccaagga ttgtctgatt
    20221 ccttcttcat ggatttgttc caagagttga tttgcattgt tcaaaagact ttctacttct
    20281 tcctttctat ctgtcgcaga ttattggttg ctatctacca tgtactccta aaacaggaga
    20341 gttataatcc aagattacaa ggccttacag aaataagaaa tccagataag acaatgttcg
    20401 tccaagacgc tattcgcttc gcacagcagc acagattcaa tatactttaa ttttaaagtt
    20461 taggtgtcaa gacctctttt tagtgtgccc aaaatttaga gaagtaatca atcaactaac
    20521 ttttattttt ttcaaacttt cagtaaactg acctaaagct aactcaatct gtctttgtag
    20581 atgcttctgc tatcagctag aagttgatct acttttgcca agactgcctt ctcatcaaaa
    20641 gttccaggtt gatagttgga ttgcagggat ggaatcttgt ttttcaaagc cgcttcatat
    20701 cccttagttt gaaccttgat gtagtgattg tggtcgccat gaggaatcac aaaaccttct
    20761 gaatcttcac ttataattcg attggcatca aaaaccatga ccatcttctt cctcatggtg
    20821 gacatgtagt gacggattac ttaatacaga actagaagaa cttcctacct cttccgtgtt
    20881 agagtgtgat gggggattgt taagagatga cttaggaata tagtgatagt gttccccatg
    20941 tcttactata taagcatcac ctatatctct gacaatatca ttagggttaa agacatatgt
    21001 ggctgctaat tcacctgccg acaagtcact ctcaggaatg aaatgatagt gaccaccatg
    21061 tggtactata gtaggttgaa atagaatatg agcaaattga taaggggatt ttaaagtaat
    21121 ttctaacaat gatttagaaa ctatgatgtg ctattctaaa ttcaactcac tatatataac
    21181 catcatcggt agtataacgt ccctgtaatt ttgctacaga tacttctgca ctagctcctt
    21241 tatcgtcttt accatgttct tgtttttggc gattgatttc atcttttgtt cgtacatttt
    21301 ctgcatgagc ttgatcttta aggtaaacat aatactttcc atctacctta ataatatatc
    21361 ctcccttaac ctaactgacg atatcttgat ctttcggctg atagttgggg gctttcatta
    21421 gtagctcttc actaaagagc gcatcaaaag gaactttacc attatagtag tgataatgat
    21481 cgccatgaga agttacataa ccttgatctg taatcttaat aacaatttgt tttgcttgaa
    21541 ttccttcttt ttgactaacc tagtctggag tcaaattttc agtcttctta gtgtctttat
    21601 tactgtttac atatgaaaca cgatttttat ctgtattggc ctgttagcta tgttggttca
    21661 gagcataaac acacagactt aaggaaagga taacaacaga tccagctgct atatatttct
    21721 tttt
//
LOCUS       DAVMCG010000033        20928 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVMCG010000033 DAVMCG010000000
VERSION     DAVMCG010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20928
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.034"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(1..939)
                     /locus_tag="VYP66_001493"
                     /pseudo
     CDS             complement(1..939)
                     /locus_tag="VYP66_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            1195..2055
                     /gene="speE"
                     /locus_tag="VYP66_001494"
     CDS             1195..2055
                     /gene="speE"
                     /locus_tag="VYP66_001494"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1851032.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            2052..3311
                     /locus_tag="VYP66_001495"
     CDS             2052..3311
                     /locus_tag="VYP66_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1851033.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            3311..4438
                     /gene="nspC"
                     /locus_tag="VYP66_001496"
     CDS             3311..4438
                     /gene="nspC"
                     /locus_tag="VYP66_001496"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1851034.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGSRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            4435..5520
                     /gene="aguA"
                     /locus_tag="VYP66_001497"
     CDS             4435..5520
                     /gene="aguA"
                     /locus_tag="VYP66_001497"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1851035.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            5530..6405
                     /gene="aguB"
                     /locus_tag="VYP66_001498"
     CDS             5530..6405
                     /gene="aguB"
                     /locus_tag="VYP66_001498"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1851036.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(6586..7395)
                     /locus_tag="VYP66_001499"
     CDS             complement(6586..7395)
                     /locus_tag="VYP66_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1851037.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            7667..7888
                     /locus_tag="VYP66_001500"
     CDS             7667..7888
                     /locus_tag="VYP66_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEV1851038.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            7942..8613
                     /locus_tag="VYP66_001501"
     CDS             7942..8613
                     /locus_tag="VYP66_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1851039.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8665..8862)
                     /locus_tag="VYP66_001502"
     CDS             complement(8665..8862)
                     /locus_tag="VYP66_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1851040.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            8855..9763
                     /locus_tag="VYP66_001503"
     CDS             8855..9763
                     /locus_tag="VYP66_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1851041.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            9760..10221
                     /locus_tag="VYP66_001504"
     CDS             9760..10221
                     /locus_tag="VYP66_001504"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1851042.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            10211..11098
                     /locus_tag="VYP66_001505"
     CDS             10211..11098
                     /locus_tag="VYP66_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1851043.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            11101..12973
                     /gene="cbpE"
                     /locus_tag="VYP66_001506"
                     /gene_synonym="pce"
                     /pseudo
     CDS             11101..12973
                     /gene="cbpE"
                     /locus_tag="VYP66_001506"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
     gene            13053..14183
                     /locus_tag="VYP66_001507"
     CDS             13053..14183
                     /locus_tag="VYP66_001507"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1851044.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            14193..15455
                     /locus_tag="VYP66_001508"
     CDS             14193..15455
                     /locus_tag="VYP66_001508"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1851045.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVAFPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            15459..16256
                     /gene="proC"
                     /locus_tag="VYP66_001509"
     CDS             15459..16256
                     /gene="proC"
                     /locus_tag="VYP66_001509"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1851046.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     SSLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            16476..17114
                     /locus_tag="VYP66_001510"
     CDS             16476..17114
                     /locus_tag="VYP66_001510"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1851047.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            17111..18001
                     /locus_tag="VYP66_001511"
     CDS             17111..18001
                     /locus_tag="VYP66_001511"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1851048.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFESLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            18041..18358
                     /gene="yabA"
                     /locus_tag="VYP66_001512"
     CDS             18041..18358
                     /gene="yabA"
                     /locus_tag="VYP66_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1851049.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            18361..19230
                     /gene="rsmI"
                     /locus_tag="VYP66_001513"
     CDS             18361..19230
                     /gene="rsmI"
                     /locus_tag="VYP66_001513"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1851050.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETSLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            19457..19975
                     /locus_tag="VYP66_001514"
     CDS             19457..19975
                     /locus_tag="VYP66_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEV1851051.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENIHSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            20084..20221
                     /locus_tag="VYP66_001515"
     CDS             20084..20221
                     /locus_tag="VYP66_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1851052.1"
                     /translation="MDFEYFYNREAKRFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     K"
     gene            20228..20731
                     /locus_tag="VYP66_001516"
     CDS             20228..20731
                     /locus_tag="VYP66_001516"
                     /inference="COORDINATES: protein motif:HMM:NF018653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEV1851053.1"
                     /translation="MSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVK
                     KGIGLIERVRLGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQ
                     EVKNLDSNYIENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIR
                     LPAKLES"
     gene            complement(20720..>20928)
                     /locus_tag="VYP66_001517"
     CDS             complement(20720..>20928)
                     /locus_tag="VYP66_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1851054.1"
                     /translation="RKSSKLKPLTIEDKVYNHALSKERSKVENIFAKVKTFKMISTTY
                     RNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         6279 a         3736 c         4822 g         6091 t
ORIGIN      
        1 accgcagatg aggggaaccc cgtttgatca ttcttccagc taaatcaatc tgacctgact
       61 gataaataga agaatccagt ccagcgaaag cttgtaattg agcaggatta tcaaaggcat
      121 gaatatttcg aatctcggct aaaatgaccg cccctaaacg attctcaatt ccagtgaccg
      181 tcgtgatgac cgagttgaac tcagccatca agtcattgac acatgtttcc gccttgtcaa
      241 tgagcctctt gtaatgtttg atgatttcga attcacgagc aggagatgtt gttccgatag
      301 aacgaggtgc gactgagagg atatcctgaa ttttagaagc ggtcaatcgc ttaatttcta
      361 tcagcttatc aaatcctgcc tcaatccttt tctgaggatt agggtagcgt gtcaagagtt
      421 ggtaggtata ttctgaatgc tttccaacga ttttatccaa ctcaggaaag atgatatcaa
      481 gacaacgagt gtattgtact ttccaatcag actgtttttt cttgagacga tgaatatgtc
      541 tagtcagtat ttttagttct acttgccgat tatcgtgttg aaattgttca cgattggggt
      601 cagaaagaag tttaagagcg atgccatgag cgtctttctt atccgtttta gtcttgcgaa
      661 gtgataatga tttggcaaat tccttgatga gcaaaggagt gtaggtgtaa actttatatc
      721 cttgttcatg caggaagttc agtagattaa aggcataatg tccggtattt tcaagagcga
      781 tgagacagtc ttggttgagt tgtcgaagag acagatctaa gagttcaaaa ccagctttat
      841 tatttgaaaa agtgagtggt ttaagaacag ttttcctcga acattcaagg ctgtaacatc
      901 gtgtttattt ttagcgacat caatgcccac ataaagcatg ggagtacctc cagatatagt
      961 atttcaagtc tacttggtta tccacgaact ttttgccttg ttaccttaga cgagataaaa
     1021 cgtctatgcg ttatcaaact cattaccaat tgaaacaaaa agctgtggtt agaccctttc
     1081 ggaaatcgtc aagcgattgg aggaaatgaa ctaatccaca gtggcttatt ccaagtatac
     1141 cacttgggct ttggcagtag ctaactgcgc taaatataat ataaggagaa atagatggat
     1201 ttatggtttt ctgaagttca tactccagat gtcaaattgt ctctgagaac agccaagcaa
     1261 ctttacgctg gaaaaagtga atggcaggat atcgaagtct tggatacgcc agcttttggg
     1321 aaaatactga ttttaaatgg ccatgtcttg ttctcagatg cggatgattt cgtctacaat
     1381 gaaatgaccg ttcacgttcc catggctgtc cacccaaatc caaagaaagt attggttatt
     1441 gggggtggtg acggcggtgt tgcccaagta ttaacactct atcctgaact ggaacaaatc
     1501 gatatcgtgg aaccggatga gatgttggtc gaggtctgtc gtgagtattt cccagacttt
     1561 gctgcaggcc tagatgatcc tcgtgttacc atttactacc aaaatgggct acgctttttg
     1621 cgaaactgcg aatatgacta tgatattatc atcaacgatg cgacagatcc atttggccat
     1681 acggaaggac tctttaccaa ggaattctac ggcaatagtt atcgagctct gaaggaagac
     1741 ggcatcatga tttaccagca tgggagtccg ttctttgacg aggatgagtc ggcctgccga
     1801 agcatgcacc gcaaggtcaa tcaagccttt ccaatcagtc gggtttatca ggcccatatt
     1861 ccaactagcc cagctggcta ttggttgttt ggatttgcat cgaaaaaata ccaccctgtc
     1921 aaagattttg acaaggaagg ctggaaaaaa cgccagcttt tcacagaata ctacactgca
     1981 aacttacacg tgggagcctt tatgttgccc aagtatgttg aggacatttt agaagaagag
     2041 gaaggaaaaa aatgagtcgt ttactagtta ttggttgtgg gggcgttgcc caagttgcta
     2101 tttcaaagat ttgtcaagat agcgaaacat ttacagagat tatgattgct agccgtacca
     2161 agtcaaaatg cgatgacttg aaagctaaac tggaaggcaa aacaagtaca aagattgaga
     2221 cagctgctct tgatgctgac aaggttgaag aagtgattgc tctgattgaa agctacaaac
     2281 cagaagctgt tttgaatgta gctctgcctt atcaagattt aaccattatg gatgcttgtt
     2341 tggcaacagg tgttcactat atcgatacag ccaactacga agcagaagac acagaagacc
     2401 ctgagtggcg tgctatctac gaaaaacgtt gtaaggaact tggttttaca gcctactttg
     2461 actactcatg gcagtgggct tatcaagaga aattcaaaga agcaggcttg actgctcttc
     2521 ttggttctgg ttttgaccca ggtgtaacta gtgtcttttc agcttatgcc ctcaaacact
     2581 attttgatga aatccattat atcgacattt tagactgtaa tggcggtgac cacggttatc
     2641 catttgcaac caactttaat ccagaaatta atctccgtga ggtttctgcg ccaggttctt
     2701 actgggaaga tgggaaatgg gtcgaagtcg aagctatgtc tatcaagcgt gagtatgatt
     2761 tccctcaagt tggacaaaaa gatatgtatc tccttcacca tgaagaaatc gaatcattgg
     2821 ccaagaacat tccaggtgtc aaacgcattc gtttctttat gacttttggt caatcttact
     2881 tgacgcacat gaaatgtctt gaaaatgttg gactccttcg tacggatacc attaacttta
     2941 acggccaaga aattgttcca attcaatttt tgaaagcctt gcttccagat cctgctagcc
     3001 ttggtccacg tactgtaggt aaaaccaata ttggatgtat ctttacaggt gtcaaagacg
     3061 gtgtcaaaaa gactatctat atctacaatg tctgcgacca tcaggaatgt tacgcagagg
     3121 ttggttcgca agctatttct tatacgacag gagttccagc catgattggg acaaaattag
     3181 tcatgaacgg aacttggaaa caagctggag tgtataacct tgaggagtta gatccagatc
     3241 cattcatgga agctttgaat gagtatggtt tgccatgggt tgtggttgaa aatccacaaa
     3301 tggtggacta atgaagttag aacaagtacc aacaccagcc tatgttattg acttggccaa
     3361 gttagaagct aattgccgca ttctacaata tgtacaagaa gaggccggtt gcaaggtctt
     3421 gcttgcccag aaggcatatt ccctctacaa aacttatccc ttgattagcc agtatctatc
     3481 aggtacgaca gctagtggac tctatgaggc caaattggca agggaagaat ttcctggtga
     3541 agtccatgtt tttgcaccag ctttcaagga tgaggacatg gaggaattgc ttgggataac
     3601 agaccatatc gtctttaact cagagagaca gttgcgtaag catggttcgc gttgtcgaga
     3661 ggctggtgtc agtgttggtt tgcgcctcaa ccctcagtgt tcaactcaag gagatcacgc
     3721 gctctatgac ccttgtgcac caggttctcg ctttggagtt actatagaca agattccgag
     3781 tgatttgcta gatttggttg acggacttca ttttcatacc ctttgcgagc agggagcaga
     3841 tgatttacaa acaactttga aagcagtaga agaacagttt ggtccctact tacatgaggt
     3901 aaaatggctc aatatgggtg gtggtcatca tattacaaga gaaggttacg atgtggattt
     3961 gctgatttca gaaatcaagc gtatccgaaa aacttacaat cttgaaatct atatcgagcc
     4021 tggtgaagcc attgcgctta atgcgggtta tttagcaact gaggtattag atattgtaga
     4081 aaacggtatg gaaatcttgg ttttagacgc ctctgcgacc tgccatatgc ctgatgtact
     4141 tgagatgccc tatcgtccac ctttgagaaa tggctttgag gcacaggaaa aagcccatac
     4201 ctacagactt tcttctaata cctgtctgac gggcgatgtg attggtgatt atagttttga
     4261 aaatccagtc caaatcggag acagacttta ttttcaagac atggccattt attcttttgt
     4321 caaaaataat acctttaatg gtattggatt gccaagtctc tatctcatgg acgaacaggg
     4381 agactgtagc ttactcaaag cttttggcta tcaagacttt aaagggagat tatcatgatg
     4441 gacagtccaa aaaaattagg ctatcacatg ccagcagagt acgaacccca tcatggtacc
     4501 ctcatgatat ggccgactcg accaggatca tggccttttc aaggaaagga tgctaaaaga
     4561 gcatttactc agatcatcga gactatagca gaaggggaaa gagtctatct tttggtggag
     4621 caggcctatc tatctgaagc ccaatcctat cttggagaca aggttgttta tttagacatt
     4681 cccaccaatg atgcctgggc gcgtgatact ggcccaacca ttctcgtcaa tgacaaaggt
     4741 aagaaattag ccgtggattg ggccttcaat gcttggggag gcacctatga tggtctttat
     4801 caagattatg aagaggatga ccaagtagcc agtcgttttg ctgaggcctt ggaaaggcct
     4861 gtctatgatg ctaaaccttt tgtactggaa ggaggcgcaa tccatagcga tggtcaagga
     4921 actattctcg taactgaaag ttgcttgctt agtcctggtc gcaatcctaa cttgactaaa
     4981 gaggagattg aaaacacatt attagaaagt cttggtgctg aaaaagttat ttggcttcct
     5041 tatggtattt atcaggatga aaccaatgaa cacgtcgata atgttgctgc ctttgttggt
     5101 cctgctgagg ttgttttggc ttggacagat gacgaaaatg atccccagta tgccatgtca
     5161 aaagcagatc tcgaactctt agaacaggaa acagatgcaa aaggttgtca cttcaccatt
     5221 cataaattgc ctatccctgc agttcgacaa gttgtgacag aagaagattt gccaggctac
     5281 atctatgaag aaggagaaga agagcgatac gcaggtgaac gactagcagc ttcctacgta
     5341 aacttttata tcgccaacaa ggctgtcttg gttccacagt ttgaggatgt aaacgaccaa
     5401 gtggccttag atatcctcag caagtgtttc ccagaccgta aagttgtcgg aataccagcc
     5461 agagatattc tcttaggtgg tggcaatatc cactgtatca cccaacaaat tccagaatag
     5521 gagaaaaaga tgagaaatgt aagagttgca accattcaga tgcaatgcgc taaggatgtg
     5581 gcaacaaata tccaaaccgc agagcgttta gtacgtcagg ctgctgagca aggagcccaa
     5641 attattctct tgcccgagtt gtttgaacat ccctatttct gtcaggaacg tcagtatgac
     5701 tactaccagt atgcccaatc tgtagcggaa aatactgcca ttcagcattt taaggtgatt
     5761 gctaaggaac tacaagttgt tttaccaatc agtttctatg aaaaagatgg taatgtcttg
     5821 tataactcta ttgccgtcat tgatgcagat ggggaagtgc tgggcgttta tcgaaagacc
     5881 catataccag atgaccatta ttatcaagaa aaattctatt tcacgcctgg taacactggt
     5941 ttcaaggtct ggaatactcg ctatgctaag attggtatcg gtatctgttg ggatcaatgg
     6001 ttccctgaaa cagcgcgctg tcttgcattg aatggtgctg aattgctctt ttatcctaca
     6061 gctatcggtt cagagccaat tttggataca gatagttgtg gtcactggca acgtactatg
     6121 caagggcacg cagcagcgaa tattgttcca gtcatcgcag ccaatcgtta tggtttagag
     6181 gaggttactc ctagtgagga aaatggcgga cagagttcca gtcttgactt ctacggttcc
     6241 tcctttatga cggatgaaac aggagctatt ctagaacgag ctgaaagaca agaagaagct
     6301 gttctgttag ctacttatga cctagacaag ggagcaagtg aacgtctaaa ctggggcttg
     6361 tttcgagata gaagaccaga aatgtataga caaattacag attagtgtgg gagaaatgag
     6421 agattcattc tgctagacta acttcttatt agcaactata agatactatg gcatctagta
     6481 aatcgatttt tatgattcgc tattcttgtc tattgattag tccgtatttt aaaatattag
     6541 caaaaaagca aatagcagta acttctgtct atttgctttt cttttttata gaatatattt
     6601 ctcaatagca cgcgcaacgc cgtcttcttc gttgcttgag gtaacggcat ccgcaagaga
     6661 tttgacataa tcgctggcat ttcccattgc aatcccaagc cctgcaaact ggagcatttc
     6721 gatatcgtta ttagcatcgc ccatggccat aatctctgag gaatcaatct tcaaaatctc
     6781 agctagtcgt gaaagagcag tagcctttgt cgttccaagt ggcattgctt cataaatgac
     6841 aggctgcgaa cgaactccac tgaatcgttg gcaaagctct tcagcaaaac gctgctcaaa
     6901 atcgtctgtt tgttcttttg ttcctaaaaa cataccttgg aacatccgga actttccact
     6961 agtcgcttct tcaagagaaa tttcagtcag gtctgaaaat actagtttag catcattttc
     7021 aataacttga ttgggtttgc caccgagaac aaaataatgt gactcgtcaa aaagtgtcaa
     7081 ctgaacatca ctcttttcag caaggtcata gaggtattcg atgtcagctg gactcagttc
     7141 ttgccagtca accaagcccc agtcgctagt ctggtgagtt gaacaaccgt tgttaacaat
     7201 cacatactca ttctggaggt cgagtcccag ttttttgtag taggggagga caccgaaaag
     7261 ggggcgaccc gtacagagga ccagtttgac acctttttca atggcttggt gaatagcagc
     7321 gatgtgagcc tgtgggattt ccttggcttc attgaggagg gttccatcca tatccaaggc
     7381 tagtagttta atcataggtc ttccttcttt atcttttggt attattatag catattttgg
     7441 agaagaaatt gatagaaagt ttgagactaa ttgattttat agtttaagat gttttgatga
     7501 caattcatga tttgaagagg atatttggca aagatatgct atactatgtt tgtcaatgtt
     7561 gcaactagac aaattaaaaa accaacttaa tataatagtt tttttgtaag taggtatgag
     7621 tatcagatta ctcaactaat ctgaagaata atggaggaaa tatatcatga ttttaatgac
     7681 aaaaaatata aatctaacaa atgaagaatt agagctgata caaggtggag cagattcata
     7741 tggtaaaaat cctaatggta ggtacgattg ggaaatagaa ccagtattaa ctctgccggt
     7801 tcatggattt tgtcccagag gcacctatga tttaggatat attggaggag gcaatcatct
     7861 ttgcaaagga agtgctgcga gattttaagt aaaatttatt agtaatatga agaaacaagg
     7921 ggagaaagca gagaatttaa tatgaaaaaa cgggctattc aaattttact agcattgtcc
     7981 ttaatttttt acaaatcaac ttggttttgg agagttttca atcacctcgc aaagccctat
     8041 ctaccagcaa gtcgtgaatt ttttcagatt ctgcttttga tggagagcgg agttcttttc
     8101 ttagcggtca tctatctact ggtttttgca ggaaaaaaaa tttttcattt caagtggcag
     8161 ctgaggtact tcatctacct tttactgggc tacatcattt catatatgtc tgacttcctc
     8221 ttttcgtatt tcatatccct gtcttcaaat cagatttctt tgaatgaaac ggtagaaatg
     8281 atggggagac aggagttccc ttatttcttg ctcatcgttt gcttcatcgc ccctattgct
     8341 gaggaattga tttatcgcgg tgtgcttatg acaacctttt tcaaaaactc gccttggtac
     8401 ggagatgttt tgctttctgc tattattttc ggttatattc atatcaattt tgctttaact
     8461 cctcttgctt ttttcattta tgctagtgga ggtcttattt tagctctatt gtatcgcatg
     8521 actaaaaatc tctactatcc aatactagtt catattctca ttaatatcac tgccttctgg
     8581 gatgtgtggt tgctcctatt ttcaggaagt tagcttacta aaataatgtc ggaactttcc
     8641 ggcattttct tttttcacaa atagtcaacg tttttctttc cgatactgaa gtggtgtgta
     8701 gccacttatt tttttgaatt gattttgaaa ataagattgg cgtgagaaag gcagatagtg
     8761 aagatagtta agaagaatag gatgttcttt tttccttttt ggaaaacttc taaaatatgg
     8821 tataatgaaa agataaagaa gttgggggta gaagatgaac attcaacaat tacgctatgt
     8881 tgtggctatt gccaatagtg gtacttttcg tgaagctgct gaaaagatgt atgttagtca
     8941 gccgagtctg tctatttctg ttcgggattt ggaaaaagag ttgggtttta agattttccg
     9001 tcggaccagc tcagggactt tcttgacccg tcgtgggatg gaattttatg aaaaagcgca
     9061 agaattggtt aaaggatttg atatttttca aaatcagtat gccaatcctg aagaagaaaa
     9121 agatgaattt tccgttgcta gccagcacta tgacttcttg ccaccaacta ttacggcctt
     9181 ttcagagcgc tatcctgact ataagaactt ccgtattttt gaatcaacta ctgttcaaat
     9241 attagatgaa gtggcgcaag ggcatagtga gattgggatt atctacctca acaatcaaaa
     9301 taaaaagggg attatgcaac gggttgaaaa attaggtctg gaggtcatcg aattgattcc
     9361 tttccatacc catatttatc tccgtgaggg tcatccttta gcccagaaag aggaattagt
     9421 catggaggat ttagcggatt taccaacggt tcgtttcact caagagaaag acgagtacct
     9481 ttattattca gagaactttg tcgataccag cgctagctca cagatgttta atgtgacaga
     9541 ccgtgccacc ttgaatggta ttttggagcg gacggacgcc tatgcgacag gttctggatt
     9601 tttagatagt gacagtgtta atggcattac agttattcgt ctcaaggata acctagataa
     9661 ccgcatggtc tatgttaaac gtgaagaagt ggagcttagt caagctggga ctctcttcgt
     9721 agaagtcatg caagaatatt ttgatcaaaa gaggaaatca tgaaaaaaag agcaatagtg
     9781 gcagtcattg tactgctttt aattgggctg gatcagttgg tcaaatccta tatcgtccag
     9841 cagattccac tgggtgaagt gcgctcctgg attcccaatt tcgttagctt gacctacctg
     9901 caaaatcgag gtgcagcctt ttctatctta caagatcagc agctgttatt cgctgtcatt
     9961 actctggttg tcgtgatagg tgccatttgg tatttacata aacacatgga ggactcattc
    10021 tggatggtct tgggtttgac tctaataatc gcgggtggtc ttggaaactt tattgacagg
    10081 gtcagtcagg gctttgttgt ggatatgttc caccttgact ttatcaactt tgcaattttc
    10141 aatgtggcag atagctatct gacggttgga gtgattattt tattgattgc aatgctaaaa
    10201 gaggaaataa atggaaatta aaattgaaac tggtggtctg cgtttggata aggctttgtc
    10261 agatttgtca gaattatcac gtagtctcgc gaatgaacaa attaaatcag gccaggtctt
    10321 ggtcaatggt caagtcaaga aagctaaata cacagtccaa gagggtgatg tcgtcactta
    10381 ccatgtgcca gaaccagagg tattagagta tgtggctgag gatcttccgc tagaaatagt
    10441 ctaccaagat gaggatgtgg ctgtcgttaa caaacctcag ggaatggttg tgcacccgag
    10501 tgctggtcat accagtggaa ccctagtaaa tgccctcatg tatcatatta aggacttgtc
    10561 gggtatcaat ggggttctgc gtccagggat tgttcaccgt attgataagg atacgtcagg
    10621 tcttctcatg attgctaaaa acgatgatgc gcatctagta cttgcccaag aactcaaaga
    10681 taaaaagtct ctccgcaaat attgggcgat tgttcatgga aatctgccta atgatcgtgg
    10741 tgtaattgaa gcgccgattg gccggagtga aaaagaccgt aagaaacagg ctgtaactgc
    10801 taaagggaag cctgcagtga cgcgttttca cgtcttggaa cgctttggcg attatagctt
    10861 agtagagttg caactggaga cagggcgcac tcatcaaatc cgtgtccaca tggcttatat
    10921 cggccatcca gtcgctggtg atgaggtcta tggtcctcgc aagactttga aaggacatgg
    10981 acaatttctt catgccaaga ctttaggttt tactcatccg agaacaggta agaccttgga
    11041 atttaaagca gatatcccag agatttttaa ggaaaccttg gagagattga gaaagtaagg
    11101 atgaaaaaga aattaactag tttagcactt gtaggcgctt ttttaggttt gtcatggtat
    11161 gggaatgttc aggctcaaga aagttcagga aataaaatcc actttatcaa tgttcaagaa
    11221 ggtggcagtg atgcgattat tcttgaaagc aatggacatt ttgccatggt ggatacagga
    11281 gaagatagac ggtagtgatt ctcgctatcc atggagagaa ggaattgaaa cgtcttataa
    11341 gcatgttcta acagaccgtg tctttcgtcg tttgaaggaa ttgggtgtcc aaaaacttga
    11401 ttttattttg gtgacccata cccacagtga tcatattgga aatgttgatg aattactgtc
    11461 tacctatcca attgaccgag tctatcttaa gaaatatagt gatagtcgta ttactaattc
    11521 tgaacgtcta tgggataatc tgtatggcta tgataaggtt ttacagactg ctgcagaaaa
    11581 aggtgtttca gttattcaaa atatcacaca aggggatgct cattttcagt ttggggacat
    11641 ggatattcag ctctataatt atgaaaatga aactgattca tcgggtgaat taaagaaaat
    11701 ttgggatgac aattccaatt ccttgattag cgtggtgaaa gtcaatggca agaaaattta
    11761 ccttgggggc gatttagata atgttcatgg agcagaagac aagtatggtc ctctcattgg
    11821 aaaagttgat ttgatgaagt ttaatcatca ccatgatacc aacaaatcaa ataccaagga
    11881 tttcattaaa aatttgagtc cgagtttgat tgttcaaact tcggatagtc taccttggaa
    11941 aaatggtgtt gatagtgagt atgttaattg gctcaaagaa cgaggaattg agagaatcaa
    12001 cgcagccagc aaagactatg atgcaacagt ttttgatatt cgaaaagacg gttttgtcaa
    12061 tatttcaaca tcctacaagc cgattccaag ttttcaagct ggttggcata agagtgcata
    12121 tgggaactgg tggtatcaag cgcctgattc tacaggagag tatgctgtcg gttggaatga
    12181 aatcgaaggt gaatggtatt actttaacca aacgggtatc ttgttacaga atcaatggaa
    12241 aaaatggaac aatcattggt tctatttgac agactctggt gcttctgcta aaaattggaa
    12301 gaaaattgat ggaatctggt attattttaa caaagaaaat cagatggaaa ttggttgggt
    12361 tcaagataaa gagcagtggt attatttgga tgttgatggt tctatgaaga caggatggct
    12421 tcaatatatg gggcaatggt attactttgc tccatcaggg gaaatgaaaa tgggctgggt
    12481 aaaagataaa gaaacctggt actatatgga ttctactggt gtcatgaaga caggtgagat
    12541 agaagttgct ggtcaacatt attatctgga agattcagga gctatgaagc aaggctggca
    12601 taaaaaggca aatgattggt atttctacaa gacagacggt tcacgagctg tgggttggat
    12661 caaggacaag gataaatggt acttcttgaa agaaaatggt caattacttg tgaacggtaa
    12721 gacaccagaa ggttatactg ttgattcaag tggtgcctgg ttagtggatg tttcgatcga
    12781 gaaatctgct acaattaaaa ctacaagtca ttcagaaata aaagaatcca aagaagtagt
    12841 gaaaaaggat cttgaaaata aagaaacgag tcaacatgaa agtgttacaa attcttcaac
    12901 tagtcaagat ttgacatcct caacttcaca aagctctgaa acgagtgtaa acaaatcgga
    12961 atcagaacag tagtagaaaa gaaggtttta gggccttctt tttcctatca actcttttct
    13021 atttcctgtt attcatgtta taatggataa atatgaataa tcggagtgag actatgaaat
    13081 acaaacggat tgtctttaag gtgggtactt cttctctgac aaatgaggat ggaagtttat
    13141 cacgtagtaa ggtaaaggat attacccagc agttggctat gctgcacgag gctggtcatg
    13201 agttgatttt ggtgtcttca ggtgccattg cggctggttt tggagcctta ggatttaaaa
    13261 agcgtccgac taaaattgct gataaacagg cttcagcagc ggtagggcag ggacttttgt
    13321 tggaagaata tacgaccaat cttctcttgc gtcaaatcgt ttctgcacaa atcttgctga
    13381 cccaagatga ctttgtggat aagcgtcgtt ataaaaatgc ccatcaggct ttgtcggttt
    13441 tgctcaaccg tggggcaatt cctatcatca atgagaatga tagtgtcgtt attgatgagg
    13501 tcaaggttgg ggacaatgac actctaagtg cccaagtagc ggcgatggtc caagcagacc
    13561 ttttggttct cttgacagat gtggacggtc tctatactgg aaatcctaat tcagatccaa
    13621 gagccaaacg cttggagaga atcgagacca tcaatcgtga gattattgat atggctggtg
    13681 gagctggttc gtcaaacgga actgggggta tgttaaccaa aatcaaggct gcaactatcg
    13741 cgacggaatc aggagttcct gtttatatct gctcatcctt gaaatcagat tccatgattg
    13801 aggcggcaga ggagaccgag gatggttctt actttgttgc tcaagagaag gggcttcgta
    13861 cccagaaaca atggcttgcc ttctatgctc agagtcaagg ttctatttgg gttgataaag
    13921 gggctgcgga agctctctct caacatggaa agagtcttct cttatctggt atcgttgaag
    13981 cagaaggagc cttttcttac ggtgatatcg tgacagtatt tgacaaggaa agtggaaaat
    14041 cacttggaaa aggacgcgtg caatttggag catctgcttt ggaggatata ttgcgttctc
    14101 aaaaagccaa gggtgtcttg atttaccgtg acgactggat ttccattact cctgaaatcc
    14161 aactactttt tacagaattt tagaggtaaa ctatggtgag tagacaagaa caatttgaac
    14221 aggtacaggc tgttaaaaaa tcgattaaca cagctagtga agaagtgaaa aatcaagcct
    14281 tgctagccat ggctgatcac ttagtggctg ctactgagga aattttagcg gctaatgccc
    14341 tcgatatggc agcggctaag gggaaaatct cagatgtgat gttggatcgt ctttatttgg
    14401 atgcagatcg tatagaagcg atggcaagag gaattcgtga agtggttgcc ttcccagatc
    14461 caatcggtga agttttagaa acaagtcagc ttgaaaatgg tttggttatc acaaaaaaac
    14521 gtgtagctat gggtgtcatc ggtattatct atgaaagccg tccaaatgtg acgtctgatg
    14581 cggctgcttt gactcttaag agtggaaatg cggttgttct tcgtagtggt aaggatgcct
    14641 atcaaacaac ccatgccatt gtcacagcct tgaagaaggg cttggagacg actactattc
    14701 acccaaatgt gattcaactg gtggaagata ctagccatga aagtagttat gctatgatga
    14761 aggccaaggg ctatctagac ctcctcattc ctcgtggagg agctggcttg atcaatgcag
    14821 tggttgagaa tgcgattgta cctgttatcg agacagggac tgggattgtc catgtctatg
    14881 tggataagga tgcagacgaa gacaaggcgc tgtctatcat caacaatgct aaaaccagtc
    14941 gtccttctgt ttgtaatgcc atggaggttc tgctggttca tgaagacaag gcagcaagca
    15001 tccttcctcg cttggatcaa atgctggttg cagagcgtaa ggaagctgga ctggaaccaa
    15061 ttcaattccg cttggatagc aaagcaagcc agtttgtttc aggtcaagca gctgagaccc
    15121 aagactttga caccgagttt ttagactatg tccttgctgt taaggttgtg agcagtttag
    15181 aagaagcggt tgcgcacatt gaatcccaca gcacccatca ttcggatgct attgtgacgg
    15241 aaaatgctga agctgcagca tactttacag atcaagtgga ctctgcagcg gtgtatgtta
    15301 atgcctcaac tcgtttcaca gatggaggac aatttggtct tggttgtgaa atggggattt
    15361 ctactcagaa attgcacgcg cgtggtccaa tgggcttgaa agagttgacc agctacaagt
    15421 atgtggttgc tggtgatggg cagataaggg agtaagagat gaagattgga tttatcggtt
    15481 tggggaatat gggtgctagc ttggcaaaat ctgtcttgca gactaggacg tcagatgaga
    15541 ttctccttgc caatcgtagt caagctaagg tagatgcttt cattgcagac tttggtggtc
    15601 aggcttccag caatgaagaa atgtttgcag aagcagatgt gatttttcta ggagttaagc
    15661 ctgctcagtt ttctgaactg ctttctcaat accagaccat ccttgaaaaa agagaaagtc
    15721 ttcttttgat ttcgatggca gctggattga ccttagaaaa actatcaagt cttatcccaa
    15781 gccaacaccg aattattcgt atgatgccta atacccctgc ttctatcggg caaggagtga
    15841 ttagttatgc cttgtctcct aattgcaggg ctgaggacag tgagatcttt tgtcagcttt
    15901 tagccaaggc tggtctcttg gttgaattag gagaaagctt aatcaatgca gcgacaggtc
    15961 ttgcaggttg tggaccagcc tttgtctatc tctttattga ggccttggca gatgcaggtg
    16021 ttcagacggg attaccacga gaaacagcct tgaaaatggc agcccaaact gtggtaggag
    16081 ctgggcaatt ggtcctagaa agccagcaac atcctggagt tttgaaagat caagtttgta
    16141 gtccaggcgg ttcgactatt gctggcgtag caagcctaga agcgcatgct tttcgaggca
    16201 cagtcatgga ggcagttcat caagcctata aacgaacaca agaactaggt aaataagagg
    16261 tagctttgac tgcctctttt atggtggttg atactcttcg aaaatcaaat tcaaactgcg
    16321 tcagcttcac cttgccgtac tcaagtacag cctgcggcta gcttcctagt ttgctctttg
    16381 attttcattg agtatgaaat gagaagacaa aaagattgtc acaaacccct atttttttga
    16441 tagaatagaa gtagtaaaaa agaaatgagt tagacatgtc aaaaggattt ttagtctctc
    16501 ttgagggacc agagggagca ggcaagacca gtgttttaga ggctctgcta ccaattttag
    16561 aggaaaaagg agtagaggtg ttgacgaccc gtgaacctgg cggagtcttg attggggaga
    16621 agattcggga agtgattttg gatccaagtc atactcagat ggatgctaaa acagagctac
    16681 ttctctatat tgccagtcgc agacagcatt tggtggaaaa agttcttcca gcccttgaag
    16741 ctggcaagtt ggtcatcatg gatcgtttta tcgatagttc tgttgcctat cagggatttg
    16801 gtcgtggctt agatattgaa gccattgact ggctcaatca gtttgcgaca gatggcctca
    16861 aacccgattt gacactctat tttgacatcg aggtggaaga agggctggct cgtattgctg
    16921 ctaatagtga ccgcgaggtt aatcgtttgg atttggaagg gttggacttg cataaaaaag
    16981 ttcgtcaagg ctacctttct cttctggata aagagggaaa tcgcattgtc aagattgatg
    17041 ctagtctccc tttggagcaa gttgtggaaa ctaccaaggc tgtcttattt gacggaatgg
    17101 gcttggccaa atgaaacaag atcaactaaa ggcttggcaa ccagctcagt ttgaccgttt
    17161 tgtccgtatc ttagaacaag accagctcaa tcacgcctat ctcttttcag gtttctttga
    17221 aagcttggaa atggcgcaat ttttagctaa gagcctcttt tgtacggata aagttggcgt
    17281 cttaccatgt gagaaatgcc gaagttgcaa gctgattgaa cagggagagt ttccagatgt
    17341 caccttgatt aagccagtca atcaggtcat caagacagaa cgcattcggg aattggtggg
    17401 acagttttct caagcaggga ttgaaagcca gcaacaggtc tttatcatcg agcaagcgga
    17461 taaaatgcat cccaacgcag ccaattctct gctcaaggtc atcgaagaac cccagagtga
    17521 agtttatatt ttcttcttga ctagcgatga ggaaaagatg ttaccgacaa tccgaagtcg
    17581 gactcagatc ttccacttta aaaagcaaga agaaaaactt atcttactct tagaacaaat
    17641 gggacttgtt aagaaaaaag cgactctttt agctaagttt agtcaatcgc gagctgaagc
    17701 agaaaagttg gctaatcagg caagtttttg gaccttggtc gatgaaagtg aacgcctgct
    17761 gacttggtta gtagctaaga aaaaagaaag ttatctacag gttgccaaat tagccaactt
    17821 ggcagatgat aaggaaaaac aggatcaggt tttacggatt cttgaagttc tctgtgggca
    17881 ggacctcttg caggtaagag taagagtgat tctacaagat ttactagaag ctagaaaaat
    17941 gtggcaagct aatgtcagct ttcaaaatgc catggaatat ctggtcttga aagaaatata
    18001 aactcaaaaa tgaatgataa agaaaggaaa gggctgtttt atggacaaaa aagaattatt
    18061 tgacgcgctg gatgattttt cccaacagtt attggtaacc ttggccgatg tggaagccat
    18121 caagaaaaat ctcaagagcc tggtagagga aaatacagct cttcgtttgg aaaattctaa
    18181 gttgcgagaa cgcttgggtg aggtggaagc agatgctcct gtcaaggcca agcatgttcg
    18241 tgaaagtgtc cgtcgcattt accgtgatgg atttcacgta tgtaatgatt tttatggaca
    18301 acgtcgagag caggacgaag aatgtatgtt ctgtgatgag ttgttataca gggagtaggc
    18361 atgcaaattc aaaaaagttt taaggggcag tctccctatg gcaagctgta tctagtggca
    18421 acgccgattg gcaatctaga tgatatgact tttcgtgcta tccagacctt gaaagaagtg
    18481 gactggattg ctgctgagga tacgcgcaat acaggtcttt tgctcaagca ttttgacatt
    18541 tccaccaagc agatcagttt tcatgagcac aatgccaagg aaaaaattcc tgatttgatt
    18601 ggtttcttga aagcagggca aagtattgct caggtctctg atgccggttt gcctagcatt
    18661 tcagaccctg gtcatgattt ggttaaggca gctattgagg aagaaattgc agttgttaca
    18721 gttccaggtg cctctgcagg aatttccgcc ttgattgcca gtggtttagc gccgcagcca
    18781 catatctttt acggcttttt accgagaaaa tcaggccagc aaaagcaatt tttcgactcg
    18841 aaaaaagact atcctgaaac tcagattttt tatgaatcgc cccatcgtgt ggcagataca
    18901 ttggaaaata tgctagaagt ctacggtgac cgctccgttg tcttggtcag ggaattgacc
    18961 aaaatctatg aagaatacca aagaggtaca atttctgaat tgctggaaag cattgctgaa
    19021 acgtctctca agggtgaatg tcttctgatt gttgaaggtg ccagtcagga tgtggaagaa
    19081 aaagacgagg aagacttgtt cttagaaatc caagctcgta tccagcaagg tatgaagaaa
    19141 aatcaagcta ttaaggaagt cgctaagatt taccagtgga ataagagtca actctacgct
    19201 gcctaccacg actgggaaga aaaacaataa agggagacag gatgtaataa ttctgtctgt
    19261 ttctgtttaa cttaattagt gatgataata taaagatgta tcacttggta tagaagcttt
    19321 ggtattaagt tttttattaa gcccatacgg aataccgatg gttggagcag cagttatagc
    19381 gttcttagaa ggtataaata gaaaaataag gtcattttaa atcaaaggat tgataaatca
    19441 gaaagaaggt gattttttgc gaacatacga aaataaagaa gaactaaaag ctgagataga
    19501 gaaaacattt gagaaatata ttttagaatt tgataatatt ccagaaaatt taaaagataa
    19561 gagagctgat gaagttgaca gaactccagc agaaaacctt gcttatcagg ttggttggac
    19621 caacttggtt cttaaatggg aagaagatga aagaaagggg cttcaagtaa aaacaccatc
    19681 ggataaattt aaatggaatc aacttggtga attatatcag tggttcacag atacctacgc
    19741 tcatttatct ctgcaagagt tgaaagcaaa attaaatgaa aatattcatt ctatctctgc
    19801 aatgattgat tcgttgagtg aggaagaatt atttgaaccg catatgagaa agtgggctga
    19861 tgaagcgact aaaacagcga cttgggaagt gtataagttt attcatgtaa atacggttgc
    19921 accttttgga actttcagaa ctaaaatcag aaaatggaag aagatagtat tataaattat
    19981 atttttaact ttaaaaaatt tcataaaaat ggttaccaaa ggcgatagaa gaaaaactat
    20041 cgtctttttc tttgcaaatt tttaagaagg gaggtgatct tgcatggact ttgaatattt
    20101 ttataacaga gaagcgaaaa gatttaactt cttaaaagta ccggagatat tagttgatag
    20161 agaagaattt cggggcttat cagcagaagc aattatcctt tattccatac ttcttaaata
    20221 gacaggaatg tcatttaaga ataactggat agacaaggaa ggcagagtat ttatctattt
    20281 tactgtcgaa gaaattatga aaagaagaaa tatctcaaag ccaactgcca taaaaacatt
    20341 agatgagctt gatgtaaaaa aaggaatagg actgatcgaa agagtaaggc ttggacttgg
    20401 taagccgaac atcatttatg ttaaagactt tatgagtata tttcaggtaa aagaaaatga
    20461 cttacagaag tcaaaaaact taacttcaga agtaaaagat tttaacctca gaagtaaaga
    20521 aaatgaactt caagaggtta agaaccttga ctctaactat atagagaata ataagagtaa
    20581 gtatagtaag agagaatata gttttggtga aaacggactt ggaacatttc aaaatgtgtt
    20641 tttagctgct gaagatatat cggatttaca aatcataatg aactcacagc ttgagaatta
    20701 cattagactt cctgcaaaac tagaatccta gttcatgatt gataatacca gcaatcaaat
    20761 tcattcgtaa tccgaagcgt ttacgatgat ttcgataggt tgttgaaatc attttaaacg
    20821 tttttacttt ggcaaagatg ttctcaacct tgcttctctc cttagatagc gcatggttat
    20881 agactttatc ttcaattgtt agcggtttga gtttgctgga tttacgtg
//
LOCUS       DAVMCG010000034        20279 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVMCG010000034 DAVMCG010000000
VERSION     DAVMCG010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.035"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            125..3226
                     /locus_tag="VYP66_001518"
     CDS             125..3226
                     /locus_tag="VYP66_001518"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1851055.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3309..4316
                     /gene="pfkA"
                     /locus_tag="VYP66_001519"
     CDS             3309..4316
                     /gene="pfkA"
                     /locus_tag="VYP66_001519"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1851056.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADSKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4375..5880
                     /gene="pyk"
                     /locus_tag="VYP66_001520"
     CDS             4375..5880
                     /gene="pyk"
                     /locus_tag="VYP66_001520"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1851057.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6571..6796)
                     /locus_tag="VYP66_001521"
                     /pseudo
     CDS             complement(6571..6796)
                     /locus_tag="VYP66_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7644..8516
                     /locus_tag="VYP66_001522"
     CDS             7644..8516
                     /locus_tag="VYP66_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1851058.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPTDDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8649..9006)
                     /locus_tag="VYP66_001523"
                     /pseudo
     CDS             complement(8649..9006)
                     /locus_tag="VYP66_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9149..9460
                     /locus_tag="VYP66_001524"
     CDS             9149..9460
                     /locus_tag="VYP66_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851059.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKECEELRQIITTIFEQKMNKHSI
                     K"
     gene            9464..10180
                     /locus_tag="VYP66_001525"
     CDS             9464..10180
                     /locus_tag="VYP66_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1851060.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEEFICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10309..11124)
                     /locus_tag="VYP66_001526"
     CDS             complement(10309..11124)
                     /locus_tag="VYP66_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1851061.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQVTNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11121..12026)
                     /locus_tag="VYP66_001527"
     CDS             complement(11121..12026)
                     /locus_tag="VYP66_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1851062.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSIVVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSHLSPAKKVFQVFVQAIDEFFDTGRYLVFGCLFASVIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            12438..14567
                     /locus_tag="VYP66_001528"
     CDS             12438..14567
                     /locus_tag="VYP66_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1851063.1"
                     /translation="MDKKYEKISQALGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGKKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            14554..15003
                     /locus_tag="VYP66_001529"
     CDS             14554..15003
                     /locus_tag="VYP66_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1851064.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            15062..15334
                     /locus_tag="VYP66_001530"
     CDS             15062..15334
                     /locus_tag="VYP66_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1851065.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGRFW"
     gene            complement(15688..15879)
                     /locus_tag="VYP66_001531"
     CDS             complement(15688..15879)
                     /locus_tag="VYP66_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851066.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16307..17065
                     /locus_tag="VYP66_001532"
     CDS             16307..17065
                     /locus_tag="VYP66_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851067.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17067..19055
                     /locus_tag="VYP66_001533"
     CDS             17067..19055
                     /locus_tag="VYP66_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1851068.1"
                     /translation="MFRLTNKLAVLNLIKNRKLYYPFALAVLLAVTLTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDNGYKIKEKEVFRYTYFGVANQEGNKLTFFEKGQNRVQPTTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19097..19741)
                     /locus_tag="VYP66_001534"
     CDS             complement(19097..19741)
                     /locus_tag="VYP66_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1851069.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(19713..>20279)
                     /locus_tag="VYP66_001535"
     CDS             complement(19713..>20279)
                     /locus_tag="VYP66_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1851070.1"
                     /translation="IEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQI
                     IRLIPNKSAEVVNQALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWE
                     RGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNL
                     KFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT         6198 a         3707 c         4289 g         6085 t
ORIGIN      
        1 aatgatgaca aaaatacaaa tggatagaaa ataaattagt aagctgatga aatttttctc
       61 aagagaagcc atttataggt gaaaatggta taatatagtg agaaggatag aggagaagtg
      121 taaattgatc gcacaactag atacaaaaac agtctatagt tttatggaaa gcgtcatttc
      181 gatcgaaaag tatgtgagag cagctaaaga atacggctac actcatttgg ctatgatgga
      241 tattgacaat ctttatggcg ctttcgactt tctagagatt acaaaaaaat acggcattca
      301 tcctttgcta gggcttgaaa tgacagtgtt tgtagatgat caggaagtga atttgcgctt
      361 tttagctcta tctagtgtgg gctatcagca gttgatgaag ctttcgacag ccaagatgca
      421 gggggagaaa acttggtcag tcctgtccca gtacctggag gatatcgcgg tcattgtgcc
      481 ttattttgat agagttgagt cgttagaact aggctgtgat tactatatag gggtttatcc
      541 agaaacacta gcaagcgaat ttcatcatcc tatcttacct ctttatcggg tcaacgcttt
      601 tgaaagcagg gatagagaag ttcttcaagt tttaacagcg attaaagaaa atctaccgct
      661 cagagaagtt cccttgcgtt cgagacaaga tgtctttata tcagcaagtt ctttagagaa
      721 actattccaa gagcgttttc cgcaagcttt ggacaattta gaaaagctta tttcaggcat
      781 ttcttacgac ttggatacta gtctgaaact gcctcgtttt aatccagcta gaccagcagt
      841 agaggagttg agagagcgtg ctgaactggg gcttgttcag aaggggttga ctagtaaaga
      901 atatcaagat agactagacc aagaattgtc tgttattcat gatatgggct ttgatgatta
      961 tttcttggtt gtttgggatt tgttgcgttt tggacgatcg aatggctatt atatgggaat
     1021 gggaaggggt tctgcagtag gcagtttggt ttcttatgcc ttagacatca cggggattga
     1081 cccagtagag aaaaatctga tttttgaacg ctttcttaat cgtgaacgct ataccatgcc
     1141 tgatattgat attgatatcc cagatattta tcgtccagat tttatcagat atgttggtaa
     1201 taaatatggt agtaaacatg cggcacaaat cgttactttt tcaacctttg gagccaagca
     1261 agctcttcga gatgtcttga aacgctttgg tgtgccagag tatgaattat ctgcaattac
     1321 taagaaaatc agttttcgtg acaatcttaa gtcggcctat gagggcaatc tccagtttcg
     1381 tcagcaaatc aatagtaagt tagaatacca aaaagctttt gagattgctt gcaagataga
     1441 gggctatcca aggcaaacct ctgtccatgc ggctggtgtt gtaattagtg accaagattt
     1501 aaccaactac attcctctaa agtatggtga tgaaattcca ctgactcagt atgatgctca
     1561 tggagttgag gctagcggac ttttgaagat ggactttctg ggactacgaa atttgacctt
     1621 tgtccagaag atgcaagagt tgcttgctga aacagaaggt attcatctga aaattgaaga
     1681 aatcgattta gaagacaaag aaacgttagc tttatttgcc tctggtaata caaaaggtat
     1741 ctttcaattt gagcaaccag gtgccattcg tctgcttaag cgtgtgcaac cagtctgttt
     1801 tgaagatgtc gtcgcgacta cttctctaaa tcgaccgggt gctagtgact atatcaataa
     1861 ttttgtggca agaaagcatg ggcaggaaga agtgactgtt ctggatccag tactggagga
     1921 tattttggct ccaacctacg gcataatgct ctatcaggag caggttatgc aggttgccca
     1981 gcgatttgct ggatttagtc ttgggaaggc cgatattttg cgtcgagcta tgggtaaaaa
     2041 ggatgcttct gctatgcatg agatgagggc ttcctttatt caaggctcca tagaagcagg
     2101 ccatactgcg gaaaaagcag agcaggtttt tgatgttctg gagaagtttg caggctatgg
     2161 ttttaacagg tcacacgcct acgcctactc agccttggcc ttccagttgg cttattttaa
     2221 aacacattat ccagccatat tttatcagat tatgttgaat tctgctaaca gtgattatgt
     2281 aacagatgcc ttagaagcag gttttgaagt agccccattg tccatcaaca cgattcccta
     2341 tcacgataaa attgccaaca aggccatcta tctaggtttg aaatccatta aaggagtcag
     2401 taatgattta gctctctgga ttattgaaca tagaccttat tctaacattg aagattttat
     2461 agctaaatta cctgagaatt atctgaaact tcctctgcta gaacctttgg taaaagttgg
     2521 tcttttcgat tcatttgaaa aaaatcgtca aaaagtattt aataacttag ctaatctatt
     2581 tgaatttgtg aaagagttgg gaagtttgtt tggagatgct atttatagtt ggcaggaatc
     2641 ggaagattgg acggaacaag aaaaatttta tatggaacaa gagcttttag ggataggtgt
     2701 cagcaaacat ccactacaag ctattgcaag taaggctatt tacccgatta ccccaatcgg
     2761 aaatttgtca gaaaatagct atgctattat tttggttgaa gttcagaaaa taaaagtgat
     2821 tcgtaccaaa aagggtgaaa atatggcctt cttacaggca gatgatagta agaaaaaatt
     2881 ggatgtcact ctcttttcag acttatatcg tcaggttgga caggaaataa aagagggagc
     2941 cttctactat gtaaaaggaa aaatacaatc acgtgatggc cgtctgcaaa tgattgcaca
     3001 agaaataaga gaagcagttg ctgaacgctt ttggatacag gtgaaaaatc atgaatcgga
     3061 tcaagaaatt tcacgtattt tagaacaatt taaaggccca atcccagtca tcatccggta
     3121 tgaagaggaa cagaaaacca tcgtttctcc ccatcatttt gtagctaaat ccaatgaatt
     3181 agaggagaaa ttgaatgaaa tcgttatgaa aacgatttat cgctaaaaat acggaaaata
     3241 gaagaatttt aaaatcaaat gtgatataat caagaagaat gttaaaagaa aaaggagcat
     3301 aaaccaatat gaaacgtatt gctgttttga ctagtggcgg agacgcacct ggtatgaacg
     3361 ctgctatccg tgcagttgtt cgtcaagcaa tttcagaagg aatggaagtg tttggtatct
     3421 atgacggata tgctggtatg gttgccggtg aaattcatcc cctagatgca gcttcagtag
     3481 gagacatcat ttctcgtggt ggtacttttc ttcactcagc tcgttatcca gagttcgctc
     3541 aacttgaagg gcaacttaaa gggattgagc aattgaaaaa acacggaatt gaaggtgtag
     3601 ttgttatcgg tggtgacgga tcttaccacg gcgctatgcg tttgactgaa catggcttcc
     3661 cagctattgg tcttccaggt acaatcgata acgatatcgt tggtactgac tttacaatcg
     3721 gttttgacac agcggttact actgccatgg acgctattga taagattcgt gatacatcat
     3781 caagtcaccg tcgtactttt gtaatcgaag ttatgggacg taacgctggt gatatcgctc
     3841 tttgggctgg tattgcaact ggtgctgatg aaatcatcat ccctgaagca gactccaaga
     3901 tggaagatat cgtagcaagc atcaaagctg gttatgaatg tggtaaaaaa cacaatatca
     3961 tcgtcttagc tgaaggtgtg atgtcagcgg ctgaatttgg tcaaaaactt aaagaagctg
     4021 gagatacaag cgaccttcgt gtaacagaac ttggacatat tcaacgtggt ggttctccaa
     4081 ctgcgcgtga ccgtgttttg gcgtcacgta tgggtgcaca tgctgttaaa cttcttaaag
     4141 aaggtatcgg tggtgttgcg gttggtattc gtaacgaaaa aatggttgaa aatccaattc
     4201 ttggtactgc agaagaaggg gcattgttta gccttactgc agaaggtaag attgtggtta
     4261 acaacccaca caaagccgat attgagctat ctagcttgaa taagagcttg tcataattta
     4321 caatttagtt aataagacca aaaaggtcat atatataaag gagtcacaaa aatcatgaac
     4381 aaacgtgtaa aaatcgttgc aactttgggt cctgcggtag aaatccgtgg tggtaaaaaa
     4441 ttcggtgagg acggatactg gggtgaaaaa cttgatgttg aagcttcagc taaaaacatt
     4501 gctaaattga ttgaagctgg tgctaacaca ttccgattca acttctcaca cggcgaccac
     4561 caagaacaag gtgagcgtat ggcaactgtt aaacttgcgg aaaaaattgc aggtaaaaaa
     4621 gttggtttcc ttcttgatac aaaaggacct gaaatccgta cagaattgtt cgaaggtgaa
     4681 gctaaagaat attcatacaa aactggtgaa aaaattcgtg ttgcaactaa acaaggaatc
     4741 aaatcaactc gtgaagtgat tgcgttgaac gttgctggtg ctcttgatat ctatgatgat
     4801 gttgaagttg gtcgtcaagt tttggttgac gatggtaaac ttggtcttcg tgtggttgct
     4861 aaagatgatg aaactcgtga atttgaagtt gaagttgaaa acgatggtat catcgctaaa
     4921 caaaaaggtg tgaacatccc taacactaaa attcctttcc cagctcttgc tgaacgcgat
     4981 aacgacgata tccgtttcgg tcttgaacaa ggtatcaact tcatcgcaat ttcattcgta
     5041 cgtactgcaa aagatgtgaa cgaagttcgt gcaatctgtg aagaaactgg aaacggacat
     5101 gttcaattgt tcgctaaaat cgaaaaccaa caaggtatcg ataacttaga cgaaatcatc
     5161 gaagcagctg atggtattat gattgctcgt ggtgatatgg gtatcgaagt accgttcgaa
     5221 atggttccag tttatcaaaa aatgattatc aagaaagtca atgctgcagg taaagttgtt
     5281 atcactgcaa caaacatgct tgaaacaatg actgaaaaac cacgtgcaac tcgttcagaa
     5341 gtatcagacg tattcaacgc tgttatcgac ggaactgacg ctacaatgct gtcaggcgag
     5401 tctgcaaacg gtaaataccc actcgagtca gtaactacaa tggctacaat cgacaagaac
     5461 gctcaagctc ttcttaatga atacggacgt cttgattcag attcatttga gcgtaactct
     5521 aagacagaag taatggcttc tgctgttaaa gatgctacta gctcaatgga tatcaaattg
     5581 gttgtaactc ttactaagac aggtcatact gcacgtttga tttctaaata ccgtccaaat
     5641 gctgacatct tagcattgac atttgacgaa ttgacagaac gtggcttgat gttgaactgg
     5701 ggtgttatcc caatgttgac agatgctcca tcttcaactg acgatatgtt cgaaatcgct
     5761 gaacgtaaag cggtagaagc aggtctcgtt gagtcaggcg atgatatcgt tatcgttgct
     5821 ggtgtgccag taggagaagc tgttcgcaca aacacaatgc gtatccgcac agtacgttaa
     5881 gaaaaatata aaaacctatc atatccagct ttctagtctg tatgatgggc tctttttttg
     5941 tccagggggg caaaaagggg gcaaaacttt cataatggat tgatactctt cgaaaatcaa
     6001 attcaaacca cgtcagcgtc gccttaccgt actcaagtac agcttgcggc tagcttccta
     6061 gtttgctctt tgattttcat tgagtatgaa ataagatatg cacaaattga ttaggaaatt
     6121 caaatgaatt tctacaaatg ttttagcaat cgtaatgtac ttgtctagat tcgatctgat
     6181 atattttcga tttaatgata tggtatttaa aacctccaaa gtagcttgct ccattctttt
     6241 acttacgtga gtgtagatgt tatttactgt tttagcgttt ttgtgttcca ctctaaccat
     6301 tatagcattc ttctcagcta gtgtactaag gagtgtgtgc ctgaaaatat gggaactaag
     6361 gggctggttt atcggtttct ctagtttagt atttgccttt tgcaaagtga tgttaaatgc
     6421 ctttctctaa atttacatat cactattgtt taacaaaatc taatctactt taggtcactt
     6481 attctttttt tgaaatgtag aatgaacttt ttcaaagttt ttcgaatctt ttaaaatctg
     6541 tttgttttat atcgccattc tccccctttt ttaattctcc ctatatagcc tgacaacttt
     6601 cccgatggta cgaatatggt tgctttcgtc taggtggatg tcggggtatt tgggattgag
     6661 tttttttaag gtagccttgg cggagtttct tgacatagtt agcgccgtct acttggaaga
     6721 tgccgatggt attatagtca atctgtgggg tattcttgat aaataggtag tcgctgtttc
     6781 ttatctttgg ctccatggac ttgctgatga cataagcgat tgggtcgtag tcgtctggga
     6841 taatggaaac tccatatcta aatcgttgtc ctgcatcgag cggctacctg cagagataaa
     6901 ctatctaaca cgagagtaag tagtctgtct gtagtcgtcc agtctgatga tttttacgat
     6961 acttcgtttt tctgatcata cagttgcctc tcggcatagg tcagaacttt accttgtctg
     7021 gatggtgccc gttggtcgta gatagattgg atatcgctag gagaatcctt ttgaactgga
     7081 gaaaagaggg catcaatcaa gctactgaat actttaacta agtcaaatat agtatttttc
     7141 ttagtagacc taaccctttt ttcataattt ccaatggtgt ttttacttat accaatctta
     7201 gtacccaatt cttattgagt tcaaccatta ctagtctata ttgttttata gttgattgag
     7261 tttggaatag tacgctgtag ctgctaaaac atttctagga attaatttgc ctttcctaat
     7321 agagttgttc atatcttatt tcaatctact atatttttcg cctctaacaa tcgcaatctc
     7381 ttctttatct acgaacgaaa tcgctttcta tttttgtaag taaagcatca cacgaaatcc
     7441 acgaaaatga aaacctttgt tgtgttttcg taaaaaattt gttgacagag cacgaaacgc
     7501 ctactataat taaatcaagc ttaaggaaat aacaaaaaaa caaatcggag ggaaagacga
     7561 tgaacacatt aaatgagaaa gtaatcaata tctgtaaagc aatagttaaa gaaactttaa
     7621 tccaagacat ttaggagaaa gaaatgaaga aatcaagaaa attagccaca ttaggaatct
     7681 gttcagcttt gtttttaggc ttggctgctt gtcaacaaca acatgctact tctgagggga
     7741 cgaatcaaag gcaaagcagt tcagcgaaag ttccatggaa agcttcatac accaacctaa
     7801 acaaccaggt aagtacagaa gaggtcaaat ctctcttatc agctcacttg gatccaaata
     7861 gtgttgatgc attttttaat ctcgttaatg actataatac tattgtcggc tcaactggct
     7921 tatcaggaga tttcacttcc tttactcaca ccgaatacga tgttgagaaa atcagtcatc
     7981 tctggaatca aaagaagggc gatttcgttg ggaccaactg ccgtatcaat agttattgtc
     8041 ttttgaaaaa ttcagtcacc attccaaagc ttgaaaagaa tgaccagttg cttttcctag
     8101 ataatgatgc gattgataaa ggaaaggtct ttgattcaca agataaggaa gagtttgata
     8161 ttctattttc gagagttcca actgaggcaa ctacagatgt caaggttcac gctgaaaaga
     8221 tggaaacatt cttctcacaa tttcaattca atgaaaaagc tcgaatgctg tctgtagtct
     8281 tgcacgacaa tctggatggc gagtatctgt ttgtaggcca cgttggggtc ttagtaccta
     8341 ctgatgacgg tttcttattt gtagagaaat tgactttcga agagccctac caagcgatta
     8401 aatttgctag taaggaagat tgctacaagt atttaggcac caagtatgcg gattatacag
     8461 gcgagggact ggctaagcct tttatcatgg ataatgataa gtgggttaaa ctttaatagt
     8521 gttatgatat gacagtaatc ttaggatttt tatttctatt tttgatgagt tggtgggtta
     8581 tttcaatcgt taatagccag aaaccacgca aaaatgaaac atttattggc tatatccaaa
     8641 gatacgatat tgatgggaat ggctatcaat cattaccgtg tcctcagaac tgagaggagt
     8701 tcttgaaatc gtaaaactac tttgaacaag agttacttca acccattgga tccgacggag
     8761 taagttgctt tcgtggatac caaaaacagc cgcaatttct tcataagtgc ggtattctcg
     8821 cacatattga agagtggcca taagaaggtc ttctaggctt aatttaggtt ttcgtccccc
     8881 ttttgtgtgt ttaagttgat aagcagtttt taatacagct aatatctctt caaaagtggt
     8941 gcgctgaaca ccaacaagac atttaaatcg tgcatcagtt agttgtttac ttgcttcatc
     9001 attcatagaa ctactatacc atattttgtt tcgcaggaag tctaatgcta aaatcttatc
     9061 agtgagaaga tttcttaaag tttattcttt gtaatttcat ctgtattagt acataattta
     9121 acttagagaa aataggagga ctaatcgaat ggaattaaaa gattttacag aaaaagaaca
     9181 ggaaatgatt aagaaaaggc ttacaatgtc taatattagt gacaaagaaa ctactgagaa
     9241 gattctggcg ctagtaccac aagacttgat taagcgaatc ccgttttttg tcagaaaaca
     9301 tgctacaaca cgtacgatta aacgcatttc aattgaacac cctgaactct acgctgtagc
     9361 tcaaacaagt ggtgagattc cagaaaaaga atgcgaagaa ttgcgtcaga ttatcacaac
     9421 tatctttgaa caaaagatga ataagcatag tattaagtag agaatgaaaa aatattttat
     9481 tggcggtttg ggaagcaatg cctatcatag caaggatttt cttcaagaac tagattcgca
     9541 ggtctatttt ctaaatccat atgaaaagca tcttcgagat gaaacagaat tgaaatcatg
     9601 gtttaaaaat gagattgtag aggaagaatt tatctgtctg ataggtcatt ctcttggagg
     9661 agatttagct cgttatctcg catcggaatt tgaagaagta aagaaactga ttcttttgga
     9721 tggtggctat ctagatttag ataagatttt acctttggat acagagttag aggaaactaa
     9781 aaattatatc aaatctcaaa ttgttttgga cttagatgtt cttacttcta aagaaaaatc
     9841 tgaagcaaag cattggtcag aaaatatgga gaaagctgta agacagtcct atcactggaa
     9901 tgttgagtat aatagatatg agttggctat aaattatgaa aatatagaag cgatactccg
     9961 cctacggaga aaaatacaag cttttaagag agaagtggga gataccttgt ttattagtcc
    10021 tcgctatcct aatgaagcta catggagaga ggaagcccta aaagaattgc cagactattt
    10081 tgatactatt tttttagaaa actttggcca tgagctttat actcaagcac ctaaagaaat
    10141 cgctagtcta atgaatgagt ggctcgctta ttttctatga gctacttgta ttgctggaaa
    10201 tggtataaga tgaaaatcta caagtcacta attttcatat aacaaaaaac gaacaggctc
    10261 tttttctgtt attcagaaga gaacttgttc gtttttatct tgattttctt aaaaagctct
    10321 atatacatag ggattttctg gtttatcgac tttggtaaag ctgtcgattt ccaaggttgg
    10381 aaggttttgt ttgagttctt tatggtagtg attgaccagt tttcctttgg ctgttatcca
    10441 agtgttgttt tcatactgcc gggtattgcc cttggtcagc aatccataga caccagaatc
    10501 tgcgatacag tggataatgc cgaatcggaa cagaaattga ctattggcat gactggggtc
    10561 gttatagaca aagcctgtaa actggattgt cttgccctca aactcatctg gatagtcgta
    10621 gatagcctcc atgacttcca tatagttttc attagtgacc tgaatactat cttgggataa
    10681 gtatttatcc gccgccgttc gcatttcctt ttcataggct gattttgaaa aataagaact
    10741 ggtatctggt ttcaaatatt ggcttgtcgt cccttcgctt gtctgaatgg ctagatccgt
    10801 tccttccgat agggggaaat gataaccttt agcagaaaca gtctgagaat ccaagctaac
    10861 agttgggaaa gttaagccga tgacaagtgg aatagccaga agagaaatac tcgtcatctt
    10921 ggctaatcgg ctgttcagat gactgtgggt tttgacttgc ttcatccaga tatacaattg
    10981 aacgatagcc aagataaaag aaagcaccat ggagatatag gccagatagg aatagtgcat
    11041 gttgatgtac tggtttagtt tgcccgacag atggaggtaa atagtcagtt caaaatagcc
    11101 agctaaaact aaaaatcgaa tcataggatg actccaatca agagagaata ggctaaaacg
    11161 accagagtca caatcgtaat gaagtgacta ataaatcgtg ctttcaagta atttttcatc
    11221 ataagaatat ttttgatatc cagcattggg ccaatgacga gaaaagccag aactggagcc
    11281 aaaccgaaac tcgagagtag agaagccccg ataaaggcat ccgcctcact acagagcgaa
    11341 agaagaaagg ccaaaatcat caagagcagg atggcaaaaa gaggagtcgc actgatagag
    11401 gtcagaatcc gagtcggaac ataaacctgt ataacagagg caaagagaca gccaaatacc
    11461 aaataacgtc ccgtatcaaa aaactcatca atggcttgca caaagacctg aaaaactttt
    11521 tttgcaggac ttaagtgaga aaaatcatgc tcatgacagg ctagacgatt ttctttttga
    11581 atcggttctt gccagaaaaa tcctagaaaa attcctagta ttacagccac aacgatggaa
    11641 cccagagctc gtaatagggc gacatggaag gagttgccaa aggcagaata ggtcgcaaaa
    11701 agaacaatgg gattgataac aggtgctgtc acaagaaaag gaacggccgt gtaacttgga
    11761 accttttttt ccagaaaacg attgatgatg gggacgattc cacattcaca ggaagggaaa
    11821 agtataccga caaaggtccc aaaaaagatt ctcccccaac gatttcgagg gagaaaatga
    11881 taaaccttgt caggtgtgat ataaacttca atcagccctg agacaatact tcctatcaga
    11941 acgaagggaa gggcttcaat gataatggag agaaaaatgg ctccagtttg aagtacacta
    12001 gatgggagtt gttgaaaagc agtcatctag tttttctttt ctgctttggc ttttttctct
    12061 ttgtcatcag ggaaagtgac ttgtttcaaa tcagggagtt tagcaaactc ttcaaacatc
    12121 ttgtccaagt cgtctcgttt tgtaaatttg acagccatag gtgtacctcg attctaaatt
    12181 ctacctctat tatactatta ttttgcggaa aagggagttt tttaatttgt tttcgatagt
    12241 tgatactctt cgaaaatctc ttcaaaccac gtcagcttcg ccttaccgta gtacggttac
    12301 tgacttcgtc agttctatcc acaacctcaa aacagtattt tgagcagcct acggctagct
    12361 tcctagtttg ctttttgatt tttattgagt atgaaaagga ttggagaaag ccttccagct
    12421 tgtggtataa tagatttatg gataaaaaat atgaaaaaat ctctcaggct ttgggagtga
    12481 cgttaaagca aattgatacc gttctaagtt tgacagctga aggggcgact attcccttta
    12541 tcgcgcgtta tcgcaaggac atgactggta gtctggatga ggtggcgatt aaggctatta
    12601 ttgatttgga taaaagtctg acaaatctca atgaccgtaa ggaagctgtc ttagctaaga
    12661 ttcaagaaca aggtaagttg accaaggaat tggaagaagc tatcttagtt gccgaaaaat
    12721 tagcagacgt tgaagaactc tatcttcctt ataaggaaaa gcgtcgtacc aaggcaacca
    12781 ttgcccgtga agctggactc tttcctcttg ctcgcttgat tttgcagaat atagttgact
    12841 tagagaaaga agctgaaaag ttcgtctgtg aaggatttgc gactggcaag gaagccttga
    12901 ccggtgcagt tgatattttg gtcgaagcct tatcggaaga tgtgaccttg cgttctatga
    12961 cttatcagga agtgctgaga cactctaaac tcacttctca agccaaggat gaaagtcttg
    13021 atgaaaagca ggtttttcag atttattatg atttttcaga gacagttgga actatgcaag
    13081 gctatcgtac cttggctctc aatcgtgggg agaaacttgg tgtcttgaag atcggttttg
    13141 aacatgcgac ggaccgtatt cttgccttct ttgctactcg tttcaaggtg aaaaatgctt
    13201 atattgatga agttgttcag caatccgtta agaaaaaggt cttgcctgct attgagcgtc
    13261 gtattcggac agaattaact gagaaagctg aagagggagc tatccaactt ttttctgaca
    13321 atctgcgcaa tctcctcttg gttgctccac tgaaagggcg cgtggttctt gggtttgacc
    13381 cagcctttcg tacaggtgcc aagctagctg tcgtggatgc aacaggaaaa atgctgacaa
    13441 ctcaggttat ttatcctgtt aaaccagcat cagctcgtca aatcgaagaa gccaagaaag
    13501 atttagcaga tttaattggt caatacggtg tagagattat tgccattgga aatggaacgg
    13561 ccagtcgtga aagtgaagct tttgtagcgg aagttctgaa agatttccct gaagtcagct
    13621 atgttatcgt taatgaaagt ggtgcttctg tctattctgc cagcgaactt gctcgtcagg
    13681 agtttccaga cttgaccgtt gaaaaacgct ctgccatttc tatcgcccgt cgtttgcaag
    13741 atcctcttgc ggaattggtc aaaatcgatc ctaagtcaat tggtgtcggt caataccaac
    13801 acgatgtcag tcagaagaaa ctctctgaga gtctggactt tgttgtcgat acagtggtta
    13861 accaagttgg tgtcaatgtc aatacagcta gcccagctct tctttcacac gtagctggac
    13921 tcaataaaac catttctgaa aatatcgtca aataccgtga ggaagaggga aaaatcactt
    13981 cacgctccca aatcaagaaa gttcctcgtt tgggggccaa ggcttttgaa caggctgctg
    14041 gtttcctccg tatccctgaa agtagcaata tccttgataa tacaggagtt catccagaaa
    14101 attacgctgc cgttaaggaa ctcttcaaat gcttggacat taaggatctg aatgaagagg
    14161 cccaaagcaa actcaagtcg ctttcagtca aggaaatggc gcaagagtta gaccttggtc
    14221 cagaaactct taaagatatc attgcagatc ttctcaaacc aggtcgagat ttccgtgatt
    14281 cctttgatgc tccagttctc cgtcaagatg tcctagatat caaggactta gtggttggaa
    14341 aaaagctaga aggagtggtg cgtaacgttg ttgatttcgg tgcttttgtt gatatcggaa
    14401 ttcatgagga cggtctcatc catatttccc atatgagtcg caagtttatc aaacacccta
    14461 gtcaagtggt ggcagttgga gatttggtga gcgtttgggt taagaaaatt gatactgaac
    14521 gtgaaaaagt taatctgtct ctcctagctc caaatgaaac tgactgatta cgtcaagcag
    14581 gtttcactag aagacttcgg cagacctttt atccatcatg tccagtggaa taggcgtcta
    14641 cgttcgacag gtgggcgatt tttccccaaa gatgggcatt tggattttaa tcccaaggtt
    14701 tatcaggaac tggggttgga cgtttttagg aaaattgtcc gacatgaact ctgtcattat
    14761 cacctttatt tccaagggaa gggctatcaa cacaaggatc gggattttaa ggaacttttg
    14821 aaagcagtgg atggattacg gtttgtacca tccttgccca atagtaactc taaaccactc
    14881 aagctttatc gttgtcaatc ctgccagcaa aggtatcagc gcaagcgtag gattgatacc
    14941 aaacgctatc gctgtggact ttgtcgaggt aaattgcttc tgataaatca gcctgaggac
    15001 tgatgaaagc cgagcctccc cgtgatatac tatgtctaac ctagcagaaa gaggaaatat
    15061 catgaacagt aaattttata aaatgagacg caatcgcatg atttcaggag ttctggcagg
    15121 tctgtcagac aagtggaatt ttgatgttac cctagttcgt ttcttgtttg ccatttttac
    15181 agttgcaaac tttggacttg gcgtgattat ctatatcatc ctagcttcta tcatgcctac
    15241 caaggaagaa atcgaagcag aaatgtacgg aacaggccca cgtaaacgca aagaagccca
    15301 agccattgac gacaatgaag gcaggttttg gtgaggttct acagaagatt tggaataagc
    15361 aaaaagcttt aaatcaatag tctaaactgc ttgatttaaa gcttttttac ttttatactc
    15421 aataaaaatc aaagtgcaaa ctaggaagcc agccacaggc tgtaatttag tcggcaatgt
    15481 gaagttgaca tagtttgcac tttgattttt gaatagtatt aataatattt cgccagcttc
    15541 atccacaaac tatagtggat tggaactaga atagtacacc tctacttcta aaacattgtt
    15601 agaaatcgat ttgactatcc tgatcgattt gtcctgttct tatttcattt tattataaaa
    15661 gcagtaattt aaactcagtt ttttaatcta tttttgctgc tgagacaata catttttgga
    15721 aaaatggtgg atgctgataa caactgataa ccagcaaata acataagcag tgccggtaaa
    15781 ttctgtaccg ataaagtgtg tgtgttcaac taagagctga ccgatgaatg gagagagcag
    15841 atagagaagt ccgatgagta tatgttcttt gtgtttcatt aaagcgcacc ttctttcctt
    15901 ataggttgaa cgacttgcaa gtgttaaatt gaatggtatg ttatctaggt aaccttacta
    15961 aaatgttagt tcccgcttcc tccttttcaa agtaagcctt ttcacactta tattttacaa
    16021 ctttaaaaat aggaaatcaa atcattttct aagtaatttt gcttatattt cacccaatct
    16081 tacaaaaatg taagattaaa gtctcttttg taaggttagg ttatggcaag cggtcttttt
    16141 ttgatgtaaa ctagactcat aaagaacaaa ggagtaacat catgaaacaa atcttacata
    16201 agaaaactag aaaaccaagt cacaaagaaa ttgagcgcgt tcagctggga tgcactatga
    16261 tgcaagctac atttcatttg atgggatatt aagaaaggag attctcatga cacttttaga
    16321 tgtaaaacac gttcaaaaaa tttataaaac acgttttcag ggcaaccaag tagaagccct
    16381 caaggatatt cactttaccg tcgaaaaggg tgactacgtt gccatcatgg gtgagtctgg
    16441 ttctggtaaa tcaactcttc tcaatattct agctatgctg gataaaccaa gtcgtggtca
    16501 ggtttacttg aatggaactg acaccgcaac cattaaaaat tcacaggcct ctagcttccg
    16561 tcgtgaaaag ttgggctttg tcttccaaga ctttaacttg ctagatactc tatctgtaaa
    16621 ggacaatatc ttgcttccgc ttgtcttgtc aagaagacct attacagaga tgatgaagaa
    16681 attggtggtg acagctgaga atctgggaat aaaccaatta caagagaagt acccttacga
    16741 gatttctggt ggccagaaac agcgtgtagc agtagcacgc gccatcatca ctgaacctga
    16801 aattctcctt gcggacgaac cgacaggagc tcttgactcc aagtcatctg cagccttact
    16861 tgatgtcttt gatgaaatca atgagcgcgg ccaaaccatt ctcatggtaa cccactcaac
    16921 agcagcagct agcagagcta aacgtgtact ctttatcaaa gacggcattc tttacaatca
    16981 aatctaccgt ggagagaaga cagaacgtca gatgttccaa gaaatctctg ataccttgac
    17041 tgtcatggca agcgaggtga attagtatgt ttcgattaac caataagtta gcggtattga
    17101 acttgattaa aaaccgcaaa ctctactatc cttttgcgct ggctgttctc ttggcagtca
    17161 ctctcaccta tctcttttac tctctaacct tcaatcctaa gattgcggaa atccgtggag
    17221 gaacaaccat tcaggctaca cttggatttg gtatgtttgt cgtcaccctt gcgtcagcca
    17281 ttatcgttct ctatgccaat agttttgtca tgaagaaccg ttccaaggaa ctaggaattt
    17341 atggcatgtt gggcttggag aagcgtcatc ttatcagtat gacctttaag gagttagtgg
    17401 tatttgggat tctaactgtt ggagcgggta tcggtattgg agccttgttt gacaagttaa
    17461 ttttcgcttt cctgctcaaa ctaatgaaat tgaaggttga gctggttgct accttccaga
    17521 cgaaagttgt cattacagtg cttgttgtct tcggtttgat tttcctaggc ctcatgttcc
    17581 tgaatgccct tcgaatcgcc cgtatgaatg ccctccagct ctctcgtgag aaagctagtg
    17641 gagagaaaaa aggtcgcttc cttcctctcc aaaccattct tggttccata agtttaggaa
    17701 ttggctatta tcttgccctt acggtaaaag atcctcttac agccttaaca accttcttca
    17761 tagctgtttt actggttatc tttgggactt atctcttgtt taatgcaggg attaccgttt
    17821 tcctccaaat cttaaagaaa aataagaaat actattacca accaaataac ctcatatctg
    17881 tttctaactt gattttccgt atgaagaaaa atgcagttgg actagcaact atcgctattt
    17941 tgtcaacaat ggttttggta accatgtcag cagcgacaag cattttcaat tccgcagaat
    18001 cctttaaaaa agttctaaat cctcatgatt ttggggtttc aggacaaaat gttgaaaaag
    18061 aagatttgga caaactcttg agccagtttg caagtgacaa tggttataag attaaagaaa
    18121 aagaagtgtt tcgttacact tactttggtg ttgcgaacca agaaggaaat aagttaacct
    18181 tttttgaaaa aggacaaaat cgtgtccaac ccacaacagt tttcatggta tttgaccaaa
    18241 aagattatga aaatatgact ggtcaaaaac tgtctctatc aggaaatgag gtcggtctct
    18301 ttgccaaaaa tgacggactg aaaggacaga aagctctaac tctaaatgat catcaatttt
    18361 ctgtcaaaga agaatttaat aaagatttca ttgtcaacca tgttccaaat aagtttaata
    18421 tcttgactac tgattacaat taccttgttg ttcctgattt acaagccttt ttggatcaat
    18481 tcccagattc ggctatctat aatcagtttt acggtggtat gaatgtagat gccagcgaag
    18541 aagaacaact caaggtcgct gaggagtatg aaaactacct caatcaattt aatgctcaat
    18601 tagacacaga aggtagctat gtttatggta gcaatctagc agatgctagt tctcagatga
    18661 gtgccctctt tggtggtgtc ttctttatcg gtattttcct atccattatc tttatggtcg
    18721 gaactgttct ggtcatctac tacaaacaaa tttctgaagg ctacgaagac cgtgaacgct
    18781 ttattatctt gcagaaagtc ggtttggacc aaaagcaaat caagcaaacc atcaacaaac
    18841 aggttttaac tgttttcttc cttcctttgc tctttgcctt catacatctc gcctttgcct
    18901 accatatgct tagcctgatt ttaaaagtga ttggtgtact ggatacgact atgatgttga
    18961 ttgtgacctt gtctatctgc gctatcttcc tcatcgccta tgtgctgatt ttcatgatta
    19021 cttcaagaag ttatcgcaag attgtgcaaa tgtaaaaaag atacctcgac ttcaaaatcg
    19081 aggtatttct tgtattctaa atgctgaaaa gttgttcgag caggaaggta actcccatgg
    19141 tcaagagacc aatagcaagg ttccgaatca tagctgttct agtcggatcc tttccaagtc
    19201 tggcactagt gtaaccagtg agaagaaggg ccacaccgac aataaggaca gtagcaggga
    19261 tgcgatattc acttgggaat atggtcactg acagcattgg aggcaaactt ctaaggaaaa
    19321 aggcaacgaa gctagaaatg gcagcgtgcc aaggattggt aaattcttca tactcaatcc
    19381 catatttttc ctctaccaga gccttgagtg gatttttaag aaagatctta ttggtcaaga
    19441 gttgggcaga agttttgcat tctccatttt ggatataagc agcatagagg gattttttgg
    19501 ctagttccct atcttggtct aacaagagtt tttctcgcga aacggcagct tcctcggtat
    19561 cttttggagt tgaaacggat acatattctc caccagccat tgaaaaggca ccagctaaga
    19621 tagccgcaaa tcctgataaa aagataatcc agatattggt cgtggcactg gcaaccccga
    19681 taaccacacc agcaatggaa ataattccat cgttagcacc aagaacacct gcgcgcagga
    19741 tatttaaacg acctgcaaaa tttgaatcga tttcgtgatt tgtttctgac gctaaatttc
    19801 aagttcaagt tagccatcca gaagtcttct ctgggtgact tgtagtccaa gcatttttta
    19861 ggatagttgt taatccactt ttcgatgaat gcgacttctt tgggagtcat tttcttggtt
    19921 cccttaggta accatctacg aatgagcctg ttgtgattct cattagttcc cctttcccaa
    19981 gaggcatagg ggtgcgcata atagatgtgc tcctcagaaa atacatcaaa caagcgattg
    20041 aattccgttc cattatctgc cgtgatggaa agaatcttgt gttgttttaa gatgagtttt
    20101 agagcctgat tgaccacctc agcactttta tttggaatca atcggatgat ctgatgtcta
    20161 ctctttcgat ccgtcaagac aagcaagcag tagtttttcg ctctcgtaag tagaaccgta
    20221 tcaatctcat aatgcccatt ctccaagcga agattgatag cttcagaccg ctgttcgat
//
LOCUS       DAVMCG010000035        20094 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVMCG010000035 DAVMCG010000000
VERSION     DAVMCG010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.036"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..242
                     /locus_tag="VYP66_001536"
     CDS             <1..242
                     /locus_tag="VYP66_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1851071.1"
                     /translation="RKSSKLKPLTAEDKACNHALSKERSKVENIFAKVKTFKMISTTY
                     RNHRKRFGLRMNLIAGIINHELGFWFRRKSIEVLS"
     gene            401..2692
                     /gene="pcrA"
                     /locus_tag="VYP66_001537"
     CDS             401..2692
                     /gene="pcrA"
                     /locus_tag="VYP66_001537"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1851072.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSVLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2735..3415
                     /gene="radC"
                     /locus_tag="VYP66_001538"
     CDS             2735..3415
                     /gene="radC"
                     /locus_tag="VYP66_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1851073.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3412..4101)
                     /locus_tag="VYP66_001539"
     CDS             complement(3412..4101)
                     /locus_tag="VYP66_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1851074.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGKPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4119..4760)
                     /locus_tag="VYP66_001540"
     CDS             complement(4119..4760)
                     /locus_tag="VYP66_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1851075.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4843..5058)
                     /locus_tag="VYP66_001541"
     CDS             complement(4843..5058)
                     /locus_tag="VYP66_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1851076.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5066..5413)
                     /locus_tag="VYP66_001542"
     CDS             complement(5066..5413)
                     /locus_tag="VYP66_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1851077.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5418..6533)
                     /locus_tag="VYP66_001543"
     CDS             complement(5418..6533)
                     /locus_tag="VYP66_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1851078.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMH
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6543..7502)
                     /locus_tag="VYP66_001544"
     CDS             complement(6543..7502)
                     /locus_tag="VYP66_001544"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1851079.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7615..8184)
                     /locus_tag="VYP66_001545"
     CDS             complement(7615..8184)
                     /locus_tag="VYP66_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1851080.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTLDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8312..8983
                     /locus_tag="VYP66_001546"
     CDS             8312..8983
                     /locus_tag="VYP66_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1851081.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRSITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8967..9785
                     /locus_tag="VYP66_001547"
     CDS             8967..9785
                     /locus_tag="VYP66_001547"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1851082.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9782..10678
                     /locus_tag="VYP66_001548"
     CDS             9782..10678
                     /locus_tag="VYP66_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1851083.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSYIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10722..11696
                     /gene="pta"
                     /locus_tag="VYP66_001549"
     CDS             10722..11696
                     /gene="pta"
                     /locus_tag="VYP66_001549"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1851084.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(12012..13025)
                     /locus_tag="VYP66_001550"
                     /pseudo
     CDS             complement(12012..13025)
                     /locus_tag="VYP66_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(13245..13544)
                     /locus_tag="VYP66_001551"
     CDS             complement(13245..13544)
                     /locus_tag="VYP66_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1851085.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            14015..14701
                     /locus_tag="VYP66_001552"
     CDS             14015..14701
                     /locus_tag="VYP66_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1851086.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIYDEHFLSQYAFCLVAEKSKRKSLILGVITCK
                     KIGNMLHLKS"
     misc_feature    14710..14797
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            14834..15148
                     /gene="rplU"
                     /locus_tag="VYP66_001553"
     CDS             14834..15148
                     /gene="rplU"
                     /locus_tag="VYP66_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1851087.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            15164..15508
                     /locus_tag="VYP66_001554"
     CDS             15164..15508
                     /locus_tag="VYP66_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1851088.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            15525..15818
                     /gene="rpmA"
                     /locus_tag="VYP66_001555"
     CDS             15525..15818
                     /gene="rpmA"
                     /locus_tag="VYP66_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1851089.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(16129..16335)
                     /locus_tag="VYP66_001556"
     CDS             complement(16129..16335)
                     /locus_tag="VYP66_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1980 domain-containing protein"
                     /protein_id="HEV1851090.1"
                     /translation="MTAFQQLPSSVLQTGLFFSPSVSLDSQTVSAKEYLFPYQKERAQ
                     TTQTSEGTTSQYLKPDSSFYSQLK"
     gene            16771..17688
                     /locus_tag="VYP66_001557"
     CDS             16771..17688
                     /locus_tag="VYP66_001557"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1851091.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWY"
     gene            complement(17781..18629)
                     /locus_tag="VYP66_001558"
     CDS             complement(17781..18629)
                     /locus_tag="VYP66_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1851092.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            18771..19610
                     /locus_tag="VYP66_001559"
     CDS             18771..19610
                     /locus_tag="VYP66_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1851093.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            19716..19991
                     /locus_tag="VYP66_001560"
     CDS             19716..19991
                     /locus_tag="VYP66_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1851094.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT         6041 a         3622 c         4227 g         6204 t
ORIGIN      
        1 cacgtaaatc cagcaaactc aagccgctaa cagctgaaga taaagcctgt aaccatgcgc
       61 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatga
      121 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg
      181 gtattatcaa tcatgaacta ggattttggt ttcgcaggaa gtctattgag gtattgagct
      241 agtttatgaa aaaattgggt gaaaaagtcg agtgttttag aaacccacag tgtagtattc
      301 tagtttcaat ccactatatt ttgctactcc ccgtaaagtt tctattttcc ctgatttctg
      361 atataataga aatattgact tcaagagtaa ggaagagaag atgaacgcat tattaaatgg
      421 aatgaatgac cgtcaggctg aggcggtgca aacgacagaa ggtcccttgc taatcatggc
      481 aggggctggt tctggaaaga ctcgtgtttt gacccaccgt atcgcttatt tgattgatga
      541 aaagctggtc aatccttgga atatcttggc cattaccttt accaacaagg ctgcgcgtga
      601 gatgaaagag cgtgcttata gcctcaatcc agctactcag gactgtctga ttgcgacctt
      661 ccactccatg tgtgtgcgta ttttgcgtcg agatgcggac catattggct acaatcgtaa
      721 ttttacaatt gtggatcctg gtgaacagcg aacgctcatg aaacgtattc taaaacagtt
      781 gaacttggat cctaaaaaat ggaatgaacg aactattttg gggaccattt ccaatgctaa
      841 gaatgatttg attgatgatg ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat
      901 tgtggcccag tgttatacag cctatcaaaa agaacttcgt cagtctgaat ccgttgactt
      961 tgatgatttg attatgctga ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta
     1021 ctaccagcaa aaattccaat acatccacgt tgatgagtac caagatacca accacgctca
     1081 gtaccaatta gtcaaactct tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc
     1141 ggaccagtct atctacggtt ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa
     1201 ggattacccc aaagccaagg ttgttttgtt ggaggaaaat taccgctcaa ccaaaaccat
     1261 tctccaagcg gccaacgagg ttattaaaaa taataaaaat cgccgtccta aaaatctctg
     1321 gactcaaaac gctgatgggg agcaaatcgt ttactatcgt gccgatgatg agctggatga
     1381 ggctgtattt gtagccagaa ccatcgatga acttagtcgc agtcaaaact tccttcataa
     1441 ggattttgca gttctctatc ggactaatgc ccagtcccgt acaattgagg aagccctgct
     1501 caagtctaac attccttata ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat
     1561 tcgcgatatt attgcttatc tcaaccttat tgctaatttg agtgacaata ttagttttga
     1621 gcgtattatc aacgagccta aacgtggaat tggtctaggt acagttgaga aaatccgtga
     1681 ttttgcaaat ttgcaaaata tgtctatgct ggatgcttct gctaatatta tgttgtctgg
     1741 tatcaagggt aaggcagccc aatctatctg ggattttgcc aatatgatgc ttgatttgcg
     1801 ggagcagcta gaccacttaa gcattacaga gttggttgag tccgtcctag aaaaaacagg
     1861 ttatgtcgat attcttaacg cccaagcgac tctagaaagc aaggcacggg ttgaaaatat
     1921 cgaagagttt ctttctgtta cgaagaactt tgatgacacc actgatgtga cagaagagga
     1981 aactggtctg gacaaactga gtcgtttctt aaatgacttg gctttgattg ccgacacaga
     2041 ttcaggtagt caggagacat cagaagtgac cttgatgacc ctgcatgctg ccaaaggtct
     2101 cgaatttcca gttgtctttt tgattgggat ggaagaaaat gtctttccac ttagtcgtgc
     2161 gactgaagat ccagatgaat tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg
     2221 tgcagagaaa attctctatc tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa
     2281 ttataaccgt ccgactcgtt ttattaacga aatcagttca gacttgcttg agtatcaagg
     2341 tctggctcgt cctgcaaata caagctttaa ggcatcatat agcagtggta gtatttcctt
     2401 tggtcaaggt atgagtttgg ctcaggctct tcaagaccgt aaacgcggtg ctgccccaaa
     2461 atcaatccag tcaagcgttc ttccatttgg tcaatttaca gctggcgcaa aatcagcatc
     2521 tagcgaggca aattggtcca ttggtgacat tgctctccac aagaaatggg gagagggaac
     2581 tgttctggaa gtttcaggta gcggtgctag gcaggaattg aaaatcaatt tcccagaagt
     2641 aggtttgaaa aaacttttag ccagtgtggc tccaattgag aaaaaaatct aattttccat
     2701 ccttctcacg aataataaag tgaggaggat ttttatgtac agtatttcat tccaagaaga
     2761 ttcactatta ccaagagaaa ggctggccaa ggaaggagtt gaagcgctta gtaaccaaga
     2821 gttgctagct attttactca ggacaggaac acgtcaagct agcgtttttg aaattgccca
     2881 aaaagtcttg aacaatcttt caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt
     2941 gcagagtttg tctggtattg ggcgtgttaa ggccatagaa ttacaagcta tgattgaact
     3001 ggggcatcgt attcacaaac acgagactct tgaaatggaa agtattctca gcagtcaaaa
     3061 gttggccaag aagatgcagc aggaattagg ggataaaaaa caagagcacc tggtggcact
     3121 ctatctcaat actcaaaatc aaatcatcca tcagcagacc atttttatcg gttctgtaac
     3181 tcgtagtatc gctgaaccgc gagagattct gcactatgca atcaagcata tggcgacttc
     3241 tcttatcttg gtccacaatc atccttcagg agcggtagcg cctagccaaa atgatgatca
     3301 tgtcactaaa cttgttaaag aagcctgcga actgatgggg attgttctct tggaccattt
     3361 gattgtctct cattctaatt actttagtta tcgtgaaaag acagatttaa tctaaagttc
     3421 attaacgaca tagtcaaaga gtttcttatc tttgggacga ttttcaaaaa gaagttctgg
     3481 atgccattgg acaccgagaa aggcgacatc atccgtactc atgacagcct caatgatacc
     3541 atctttagga tcatgagcca caacttttaa atttggtgct aagtccttga tgctctggtg
     3601 gtggaaggag ttgatatgag agatttctcc atagatttct tggagaacgg tatctggttc
     3661 tgttaccaag cgttgagttg tgtactcaac agaagaatcc tgccaatggt cttcgatatc
     3721 ttggtacaaa gttccaccca tggcaacgtt aaagagttgg gtaccacggc agacagagaa
     3781 aatgggcttt ttctgtttaa tagcttcctt gatgagggcc agttcgaaga tatctctttg
     3841 aaggtgataa tcatcgctat caatggtttt gggtttgcca tagaattttg gatcgacatt
     3901 ttgcccacct gtcaagatga gcttgtcaat caaactgata tagtggcagg ccatttcttg
     3961 atcaccaatc ggtaggatga taggaatccc tccagcatct ttaacgcctt caacaaagcc
     4021 ttttgctgcg tagctcatca tgatgtcatc atctggatga gttttttcgt ttcctgtaat
     4081 cccaataact ggttttttca taaaatgatt ttcgctttct aatcctcttt tcgcatgaag
     4141 tagaggaggg tttggagttc acttgtcaaa tcgacatact gaacgaccac gtcttttggt
     4201 aaatgcagat ggactggtga aaaactgaga attcctttca caccagcatc aaccaagaga
     4261 ttagcaacct cttgtgactt gacgctggga acagttagga tagcagtctt cacatcagca
     4321 tccttgattt tatccttgat ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg
     4381 gtaccgactt caggatggtc gtctaggtca aaggccatga taatcttcat cttgttacgt
     4441 tcgtggaagc ggtagtggag aagggcatgg cccatatttc caataccaac cagcatgaca
     4501 ttggtaatag agttgtcatt gagcaaatcg gcaaaaaatg tcattaattt tttgacatca
     4561 tagccaaaac cacgacgacc aagttcacca aaataggaaa aatcacgacg tacggtagct
     4621 gaatcaatac cgatagcctc tgcaatttgc ttagagttgg cacgttcaat cttttctgca
     4681 tgaaatctct taaaaattcg atagtagaga gagagtcttt ttgctgtagc ttttggaata
     4741 gcaaactgtt tatctttcac aaaatcacaa cctttctatt cttctatttt atagaaacat
     4801 tgtgaaaaaa tcaacaaaaa taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa
     4861 atctgcatga gatagaaaac ggtagaggtc tccgaccagc ccctgataaa cttttttgcc
     4921 cctaaaagtc agagaagtca cataaagtgt atctggtaag gttacacatc ctgacaaagt
     4981 caacatgaga gcctcatgat cctcatactt gagagtacgc tctacatgat agcagtcctt
     5041 ataggtcagt tcaaacattt tggctctatc tttccgattt tgtaaagaca ccacgttcta
     5101 ccaagctatc catgaggaag tagaattttt cctgatgaat atggtggtct tctgatttga
     5161 aaatatcaac tagacgaagg ccaaacttgt cagtgatatt gattttagcc cctgtaagtt
     5221 ccttgttaat gatgattttg agttggaagc cttcaccgct gtttggcact ttttccaaaa
     5281 ggcgagtcag ttcatagtta ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga
     5341 attttttaac agaagggcta agagtgtaat cgtaacgaca attttttaac tgaatgattt
     5401 tttcaaatgc catatggcta acctccgata atttctttta aggtttttgc gagggtttgt
     5461 aggtcttcaa cggtattttg tggcgacaaa ctgatgcgaa gggattcctt caagcgttct
     5521 gaatttgcgc catgcatggc tttaagaaca tggctggatt ggacaacgcc tgcagtacag
     5581 gctgagccag tagagattga aattccagct aaatctagcc gaaggagtaa gaggtcattt
     5641 ttctgaccag gaaatccaat attgagaaca taagggagat gatgttttcc tctattcaag
     5701 taatactgaa tgccctccag ctctgccaga aaggcagttt ctagattttg tacatgttga
     5761 aaatgttctt cttgtttttc taggtcttct tttagggctg caaccatgcc tacgatggca
     5821 ggcagatttt cagttcctgc acgttttttc tgttcctgat ctccgccatg tagataggaa
     5881 tcaaagtcca tgctagatgc gtagagaaaa ccgattccct taggaccatg gaatttgtgg
     5941 gcagaagcag tgagaaaatc aatgcccaat tcttctgaat gaattgggat tttaccaata
     6001 gcctgaactg catcaacatg ataggcagca gggtgttgct tgagtatttg gccaatttca
     6061 gcgatgggaa gtaggtttcc tgtctcatta ttggcaaaca tagtagaaac caaaatcgta
     6121 tcgtcacgta aagccttttg aatttgctgg gctgtgattt cttgattttc tggctggata
     6181 atggttgctt caaacccaaa gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg
     6241 tgctcgatgg cagttgtgat gatatgtttt ccttgttctt ggtgacgaag acagtagcca
     6301 atgatggtag tattattgcc ttcagtccca ccagaagtga aaaagatatg ttgaggtttt
     6361 gtccttagta actgggctag ttcctgacgg gcttctcgca agagtttgcc agcttgacga
     6421 ccatgaccat gaatactaga aggatttccg tgggtttctt gcataacctt ggtcatagct
     6481 gaaatagcaa ctgctgacat aggagtcgtt gcagcattgt ccaaataaat caaagaatca
     6541 ccttatttct ttttattgta ggcaaagagt gggctgactg gttttctttc gtgaatacgg
     6601 acgatagcat caccaattaa ctcactagca gtgatgtagc atacattttt aggagttttt
     6661 tcttttgttg ctactgaatc agtcacaaga atttctttaa tattagtatt gtcaagaagc
     6721 tcagcagctc cctcgacgaa gagaccgtgg ctagaaacag cataaatttc tgtagctcct
     6781 tcacgttcaa cgattttaga agcttcagag aaggtacgtc ctgtatttaa aatatcatca
     6841 atcaagatag ctttcttacc ttcaacatca ccaataatat aaccttcgtt acgagttgca
     6901 tcgtcttgag ggtagtcgat aatggcgata ggagcatcaa gatattcagc caggctacgc
     6961 gcacgtttga cacctgaatt tttagggcta acgacaacaa catctgaacc aagcaatcct
     7021 ttatcgcagt aatgttttgc gaatagggga acagtgaaaa gattatccac tggaatatca
     7081 aagaaacctt gaacctgaac ggcatgcaaa tcaagagtca ggatacgatc aactccagcc
     7141 ttaaccagca tattggcaac tagttttgct gtaagtggct cacgaggaca agcaatgcgg
     7201 tcttgacgtg catagccaaa atatggaagg acaacgttga tactgtgggc acttgcacgc
     7261 acacaagcat cgaccatgat taacaattcc attaggtggt tgttgacagg gaaacttgtt
     7321 gattggatga tgtaaacatc ataaccacgg acactttctt cgatatttac ttggatttct
     7381 ccgtctgaaa attgacgtga tgatagtttt ccaagtggga caccaacagc ttgggcaatt
     7441 ttttgtgcaa tctcttggtt agagttgagt gcgaaaagtt tcatgttttt tctatctgac
     7501 attatagacc gtcctctgta aactttataa atcctagtta tatttacctt acatatatga
     7561 actgggattt gtgtattttt attttttcta ttttaccaaa aaatggagat tatttcagct
     7621 atttttcata cttttgacaa atcgaaccaa ttttgaagga gctttttggt aggaaatctg
     7681 atttttctct aaaaattgtc ggaaatcctg tttgccttgc tcatgatttt ccacttcaag
     7741 ctccaattcg taatctgtca tatcaaagta tcggctctga tccagtgcca tgagaccaat
     7801 agctgttttc atttcatagc gaagcgttgt tagacaacca agaacctgcc agttcttact
     7861 ttggatacca tgtttcgcca attcatccag tactagccct tgaggaagtt cttccttact
     7921 cagatagttc tcagcatctt ttagttgcaa tttttggttg tattccatgt ttccaacact
     7981 ctgcgggact ttgagtgtca actcagccca gtcttcaaag gttcgaatgc gcatagcgac
     8041 tttcttttct cgcagttcaa aatcaagcgt gtcgatgtag taatttgttt gaagaacagg
     8101 agtgacacct gtgaactggt cttttagacg attgtattca tcttttttca atagtgtttt
     8161 caattcaatt tctaaatgtt tcatttttct tacctttttt tatcgttgaa agcggattta
     8221 tggtataata agcattgtat ttattgtata tgaatctgga gaaaaaatca aagatatttt
     8281 tgacggataa tatgagaaca agggagaata tatgacctta gaatgggaag aatttctaga
     8341 tccttacatt caagctgttg gtgagttaaa gattaaactt cgtggtattc gtaagcaata
     8401 tcgtaagcaa aataagcatt ctccaattga gtttgtgacc ggtcgagtca agccaattga
     8461 gagcatcaaa gaaaaaatgg ctcgtcgtag cattacttat gcgaccttgg aacacgattt
     8521 gcaggatatt gctggcttac gtgtgatggt tcagtttgta gatgacgtca aggaagtagt
     8581 ggatattttg cacaagcgtc aggatatgcg aatcatacag gagcgagatt acattactca
     8641 tagaaaagca tcaggctatc gttcctatca tgtggtagta gaatatacgg ttgataccat
     8701 caatggagct aagactattt tggcagaaat tcaaattcgt actttggcca tgaatttctg
     8761 ggcaacgata gaacattctc tcaactacaa gtaccaaggg gatttcccag atgagattaa
     8821 gaagcgactg gaaattacag ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat
     8881 tcgtgatgat atccaagaag cccaggcact ttttgatcct ttgagtagaa aattaaatga
     8941 cggtgtagga aacagtgacg atacagatga agaatacagg taaacgaatt gatctgatag
     9001 ccaatagaaa accgcagagt caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa
     9061 atcagtttat actcaatgat accaatccgg atattgtcat ttccattggc ggggatggta
     9121 tgctcttgtc ggcctttcat aagtacgaaa atcagcttga caaggtccgc tttatcggtc
     9181 ttcatactgg acatttgggc ttctatacag attatcgtga ttttgagttg gacaagctag
     9241 tgactaattt gcagctagat actggggcaa gggtttctta ccctgttctg aatgtgaagg
     9301 tctttcttga aaatggtgaa gttaagattt tcagagcact caacgaagcc agcatccgca
     9361 ggtctgatcg aaccatggtg gcagatattg taataaatgg tgttcccttt gaacgttttc
     9421 gtggagacgg gctaacagtt tcgacaccga ctggtagtac tgcctataac aagtctcttg
     9481 gcggtgctgt tttacaccct accattgaag ctttgcaatt aacggaaatt gccagcctta
     9541 ataatcgtgt ttatcgaaca ctgggctctt ccattattgt gcctaagaag gataagattg
     9601 aacttattcc aacaagaaac gattatcata ctatttcggt tgacaatagc gtttattctt
     9661 tccgtaatat tgagcgtatt gagtatcaaa tcgaccatca taagattcac tttgtcgcga
     9721 ctcctagcca taccagtttc tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg
     9781 aatgaggttt gaatttatcg cagatgaaca tgtcaaggtt aagacctttt taaaaaagca
     9841 cgaggtttct aagggattgc tggctaagat taagtttcga ggtggagcga ttctggtcaa
     9901 taatcaaccg caaaatgcaa cgtatctatt ggacgttgga gactacgtta ccatttacat
     9961 tcccgctgag gaaggctttg aaaccttgga ggctattgag catccattag atattctcta
    10021 tgaggatgac cactttctag tcttgaataa accctatgga gtggcttcta ttcctagtgt
    10081 caatcactct aataccattg ccaattttat caagggttac tatgtcaagc aaaattatga
    10141 aaatcagcag gttcacattg ttaccagact agatagggac acttctggct tgatgctctt
    10201 tgccaagcac ggttatgccc atgcacgatt agacaagcag ttgcagaaga aatctatcga
    10261 gaaacgctac tttgctttgg ttaagggaga tggacatttg gagccagaag gggaaattat
    10321 tgctccgatt gcgcgtgatg aagattccat tattaccaga cgagtggcta aaggcggaaa
    10381 gtatgcccat acttcataca agattgtagc ttcttatgga aatattcact tggtctatat
    10441 tcacctgcac actggtcgaa cccatcaaat ccgagtccat ttttcttata tcggttttcc
    10501 tttgctggga gatgatttgt atggtggtag tctggaagat ggtattcaac gtcaggctct
    10561 gcattgccat tacctatcct tttatcatcc atttttagag caagacttgc agttagaaag
    10621 tcccttgccg gatgatttca gtaaccttat tacccagtta tcaactaata ctctataaaa
    10681 actgtctcag agtataatta ttatcttaaa ggagaaaact catggaagtt tttgaaagtc
    10741 tcaaagccaa ccttgttggt aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc
    10801 gtattcttca agcaacaaaa cgcttagtaa aagaaacaga agtgattcct gttttgcttg
    10861 gaaatcctga aaaaattaaa atttatcttg aaattgaagg aatcatggat ggttatgagg
    10921 tcatcgaccc tcaacattat cctcaatttg aagaaatggt ttctgccttg gtggagcgtc
    10981 gcaagggcaa aatgactgaa gaagatgtac gcaaggtttt ggttgaagat gtcaactact
    11041 ttggtgtgat gttggtttac ttgggcttgg ttgatggaat ggtgtcagga gcgattcact
    11101 caacagcttc aacagttcgt ccagctctac aaatcatcaa aactcgtcca aatgtaactc
    11161 gtacttcagg agccttcctc atggttcgtg gtacggaacg ttacctattt ggagactgtg
    11221 ccattaacat caatccagat gcagaagcct tggctgaaat tgccatcaac tcagcaatca
    11281 cagctaagat gtttggcatc gaacctaaaa ttgccatgtt gagctattct actaaaggtt
    11341 cagggtttgg tgaaagcgtt gataaggtcg ttgaagcaac taaaattgct cacgacttgc
    11401 gtcctgacct tgaaatcgat ggtgagttgc aatttgatgc agcctttgtt cctgaaactg
    11461 cagctctgaa agctcctgga agtacggtag ctggtcaagc aaatgtcttc atcttcccag
    11521 gtatcgaggc aggaaatatc ggttacaaga tggctgaacg cctgggtggc tttgcggctg
    11581 taggacctgt tttgcaaggt ttaaacaagc cagttaatga tctttctcgt ggatgtaatg
    11641 cagatgatgt ttacaagttg accctcatca cagcagctca agcagttcat caatagtgaa
    11701 aactataaag cgatatacta tgctatactg tagttatgaa actatgtacg aaaagcactg
    11761 ccattaattc ctgagaacta aattactgat tggtgtcaaa aaggaaaact tccaagcgat
    11821 gatatcctgt ctatacacga cctatagaaa tctgtaatat acatgtccgt aaaacgataa
    11881 attccctttt tgattttaaa tgagtatgaa aagagaattt tttcatgaga aaacgcataa
    11941 tattaagtgt cttgacacct gctattatgc gttttctggc tctttgtcaa ctgtagtggg
    12001 ttgaagaaaa gctaagctcg agaaaggaca aattttgtcc tttctttttt gatgttcaga
    12061 gcgataaaaa tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgtgcttg
    12121 ataagtttga tgagattatt ggtggcttcc agtttggcgt tggaataagg taattgaagg
    12181 gcgttgacga ttttctcttt atctttgagg aaggttttaa acagagtctg aaaaagaggt
    12241 ggaaaagcaa gagctgatag agattatagt ggtgtttcaa gtcttcggaa tagctcaaaa
    12301 gtttatctag aatttcttta ttagtcaagt gcatacgaaa agtagggcga taaaatcgtt
    12361 tatcactcag tttctgacta tcttgttgaa tgagctttca gtatcgcttg atagccttgt
    12421 attcatggga tttcggatga tggcttgtgt tctgctctca agaacagtta tgatattgag
    12481 cttatcaaag tcctgagcaa taaagctcat ctctatctcc cgattgaaac agtcactccc
    12541 cagactgttt caacgtccta ggacataatc tcaggaagac gcgaaaaatc atgctcaaag
    12601 tgaaaatcat tgatcttgcg aatgacagtt gaagttgaaa tagacaactg atgatcaatg
    12661 tcggtcatag aagtcttttc aattagcttc tgatcaatct tttggttgat gatacaagga
    12721 atttgatgat tcttcttgac gatagaagtc tcagcgacca tcattttaga acagtgatag
    12781 cacttgaaat gacgctttct aaggagaatt ctagtaggca taccagtcgt ttcaagataa
    12841 ggaattttag aaggtttttg aaagtcatat ttcttcaatt ggtttccgca ctcaggacaa
    12901 gatggagctt catagtccag tttggcgatg atttccttgt gtgtatcctt attgatgatg
    12961 tctaaaatct ggatattagg gtctttaatg tctagtaatt ttgtgataaa atgtaattgt
    13021 tccatatgat tctttctaat gagttgtttt gtcgcttttc attataggtc atatgggact
    13081 ttttttctac acaaaaatag gctccgtaat atccataggg gatttaccca ctacaaatat
    13141 tatagagccc aaagttttag gttgcttgat actatgcgtt ttttataatt tttgcacctt
    13201 tcttagcctt tgttatcgac aagcattgtt ctagctcctt gtttttagaa tggcaatttc
    13261 ccagcgaaag cacccagttt tttcttagta gtttcatcga tttgttcaag agcagagttg
    13321 atggcttgaa cggtcatatc agaaagagtc tcaaggtctt ctgggtcaac gacagctgga
    13381 ttgaaatcaa tgctgacaac tttcttatcg ccagttaagg ttgcttggac aagatcttga
    13441 gcagatttgc caacaaattg catagcagca agttcagctt ggctttgttc catttgtttt
    13501 tgaagttttt gtgcttgacg catcatgttt tgcatgttca tcataagatt tctaaagttc
    13561 ctttcatctc aaggggataa tccttgttgt taacaagtgc ctgattttct ctcctaattg
    13621 ttattagtag catagccatc aagtccaagt attgatttta ttataccatt tttttaagac
    13681 atagtctttt attggtgaga gttatttatg tcaaggagtg attagaaata aattaaaata
    13741 atgatttttg ctaagagggg ctctattcta gtttcatgga aatgatttta ctaaaggttc
    13801 gtatgctttg tttgcaaaca tgttacctct atctattttt ggataaatag ttgtctatta
    13861 ttatttttat gctaatagta aaatctaaat ggtagcctac gattttttag aaagaaaatg
    13921 gtacaatatt tctaagagaa aatacaatgg gagggaaaat gaggttatta cctataagaa
    13981 aaatatcacg tcagtctaaa aggttagcac ttttttgacg ttttgtgctg gatatgtgga
    14041 tgcttacact tttattgttc gcgggaatac ccttgtagct ggacaagctg gaaatgttgt
    14101 ctttctttcg gtagagctca tacaaaataa tgtttcggat attagggata agcttttaac
    14161 cttaatagcg tttatgatgg gagtcttttt attaacgatt tataaggaaa aattgagaat
    14221 tgtgaaaaaa tctattctgt ccttgattcc tttagcaatc ctatcaataa ttattggttt
    14281 tgtgccacaa actgtagata atatctatct agtgccgccc ttggccttct gtatgggact
    14341 ggtgacaact gcttttggtg aggtttcggg tattgcctac aataatgcct ttatgacagg
    14401 gaatatcaaa cgaacaatgc tagcttttgg agattatttc cgaactaagc acactccttt
    14461 tttgcgtgaa gggttcatat ttgttagcct gcttagtagt tttgtccttg gcgttgtctt
    14521 ttcagtctat ttgacgattt tctatcatga aaagaccatt cttggtgttc ctatttatga
    14581 tgagcatttt ttatctcagt atgctttttg cctagtggca gaaaaaagta aaagaaaaag
    14641 cttgatttta ggtgttatta cttgtaagaa aataggaaat atgctacact tgaagagttg
    14701 actatgcacg atcctgtgca accgcacgaa catcgttgct tgattattca agtttaagtg
    14761 gtttgtccca cgatgctagg cgagtcttca caaaaaaatc ggggaaaccc ataaaaatca
    14821 taggaggtgc ataatgagca catacgcaat tatcaaaact ggcggaaaac aagttaaagt
    14881 tgaagttggt caagcagttt acattgaaaa attgaacgtt gaagctggtc aagaagttac
    14941 ttttaacgaa gttgttcttg ttggtggtga aaacactgtt gtcggaactc cacttgttgc
    15001 tggagctact gtagttggaa ctgttgaaaa acaaggaaaa caaaagaaag ttgttactta
    15061 caagtacaaa cctaaaaaag gtagccaccg taaacaaggt caccgtcaac catatacaaa
    15121 agttgtcatc aacgcaatta acgcttaatt ttaaggagaa cacatgatac aagcagtctt
    15181 tgagagagcc gaagatggcg agctgaggag tgcggaaatt actggacacg ccgagagtgg
    15241 cgaatacggc ttagatgtcg tgtgtgcatc ggtttctacg cttgccatta actttatcaa
    15301 ttctattgag aaatttgcag gctatgaacc aatcctagaa ttaaacgaag atgaaggtgg
    15361 ctatctgatg gttgaaatac caaaagatct tccttcacac cagagagaaa tgacccagtt
    15421 attctttgaa tcatttttct taggtatggc aaacttatcg gagaactctt ctgagttcgt
    15481 ccaaaccaga gttatcacag aaaactaaca cggaggaaaa cattatgtta aaaatgactc
    15541 ttaacaactt gcaacttttc gcccacaaaa aaggtggagg ttctacatca aacggacgtg
    15601 attcacaagc gaaacgtctt ggagctaaag cagctgacgg acaaactgta acaggtggat
    15661 caatccttta ccgtcaacgt ggtacacaca tctatccagg tgtaaacgtt ggtcgtggtg
    15721 gagacgatac tttgttcgct aaagttgaag gcgtagtacg ctttgaacgt aaaggacgcg
    15781 ataaaaaaca agtttctgtt tacccaatcg ctaaataaaa aggtccattg aaccttttat
    15841 cccgaacctt gaaatgtaaa ggtgaggaag ctagaaacag cttaaaataa ggctttccga
    15901 gttttcggag agcctgtttt tttgttttga tacccatact ttttaatatg tatagtggat
    15961 tgatactctt cgaaaatcaa attcaaacca cgtcagtttc accttgccgt actcaagtac
    16021 agcctgcggc taacttccta gtttgcactt taattttcat tgagtatgaa tctggaatag
    16081 aacactgtta aaaattgata tgagtttcct actcgatttc ttcagatttt atttcaattg
    16141 actataaaaa ctgctatctg gtttcaaata ttggcttgtc gtcccttcac ttgtctgagt
    16201 ggtttgagcc cgttccttct gataagggaa aagatattct ttagctgaaa cggtctgaga
    16261 atccaagcta acagatggag agaaaaatag cccagtctga agcacactag atggaagttg
    16321 ttggaaagca gtcatctagt ttttctttac tgctttggct ttttttgtca tcagggaaag
    16381 tgacttgctt caaatcaggg agtttaggaa attcttcaaa catcttgccc aagttgtctc
    16441 attttgtaaa ttttacagcc ataggtgtac ctcgattcta aattctacct tttcggcacc
    16501 aattagtaat ttaaagttct caggagttag ttgcattgct ttttcataca taagcatagt
    16561 atgacacttt atggttaccg aacaagtcta atcactcctt gcaaaatttt gaagatgtcc
    16621 tacaagtttt tgagaagaat attgcaaagt tcatagttaa gcaacgatag aataaagtgc
    16681 tttttgaaaa caggtacact tcatgtgaaa aaaaacaaca tttcagattt tctgttccag
    16741 aaatagctat cgctatgata taattatttt atgattatta ctattcctat aaaaaaccaa
    16801 aaagatattg gcacaccatc tgattcagtc gttgttctcg gctattttga tggcatacat
    16861 aaggggcatc aagaattatt tcgtgttgcc aacaaggctg cgagaaagga tttgttgcct
    16921 atcgtcgtta tgacctttaa tgaatctcca aagatcgctt tagagcctta tcatccagat
    16981 ttgtttttgc atattttgaa ccctgctgaa cgtgaaagaa aattaaagcg cgaaggtgta
    17041 gaagaattat atctccttga ttttagtagt caattcgcta gtctcactgc acaagaattc
    17101 tttgcaactt atatcaaggc tatgaatgcc aaaattattg ttgcaggttt tgattataca
    17161 tttggttctg acaaaaaaac agcagaagat ttaaaggatt actttgatgg agaagttatc
    17221 attgttccac ctgtagaaga tgagaaagga aagattagtt caactcgtat ccgtcaagct
    17281 attttagatg gaaatgtgaa agaagcagga aaacttttgg gggcaccgct tccatcaaga
    17341 ggtatggtgg ttcatggtaa tgctcgtggt cgtacaattg gttatccgac agcgaattta
    17401 gtgcttttag accgtactta tatgccagca gatggcgttt atgttgttga tgttgagatt
    17461 caaagacaga agtatcgtgc tatggctagt gtcgggaaaa atgtgacctt tgatggagaa
    17521 gaagcacgtt ttgaagtcaa tatttttgat tttaatcaag atatttatgg ggaaaccgtc
    17581 atggtttatt ggcttgatcg cattcgagat atgaccaaat ttgactcagt tgaccaatta
    17641 gtggatcagt taaaggctga tgaagaagta actcggaatt ggtattaaga gcttgagtaa
    17701 ataaaataaa aaagaggttg tctgtaaccc aaaagataga tgatttagtc taacttttga
    17761 ggtcacgaca ttacctcttt ttattctttt tcaaaggtga agccttctcc taggatttca
    17821 tgggcttctg taatagttat aaaggcttga ggatcgattc gatgaatcat ttccttcgtt
    17881 ttcacaattt catttcttcc gacaatacag tagatgattt tcaaattttc tttactatag
    17941 tagccttgac cagaaataaa agtaacacct cttccgaggt catcattaat cgccttagca
    18001 agttggtcag gacgttttgt gataatcata aagcctttgc cggcatatcc tccttcacca
    18061 atcaaatcaa taacacgaga aacaataaaa tcaaacaaaa gcgtgtagga aaccaatctc
    18121 aaatccttga agattaggag aatcaacatg agaatacaaa aatctaagat aaagagcagt
    18181 tttcctatgg atatatgagt gtatttgttg agaatacgag ctagaatatc agttccgcca
    18241 gttgtacctc cagcattaaa aataattcca aggccaattc ccaataggat tcccgctata
    18301 agggctgtga ttagtaaatc accttgaaga tcaatatgaa ggggaatatg ctcaaaaaaa
    18361 gctaaccagg cggacaaagc taaggttcct agtaaactag aatagaggga tttggctcca
    18421 aagatcttcc aagctaggat gaaaagggga atattaatca gcaggttcat gagggaaaca
    18481 gggattttaa aaagataaaa ggtgatgagg gtaatgcctg tcgcccctcc ttcaaagaga
    18541 tgatggggaa ctacaaaata agtcagtcca aaagcataaa tagcagcacc tagtaaaatg
    18601 gtaaaaatgg ggtaaatttt tttaatcata ggacacctct tttcttataa gttgattata
    18661 tcaaatttta cggaaaattt gattgactcc attaggattt ttaatctttt ttttgatata
    18721 attagaagta aggaaaccaa tctgaatcct aaaatagaaa gattgatact atgacaaaaa
    18781 ttaagattgt aaccgattca tctgttacta ttgaacctga actagtaaag caattagata
    18841 ttacaattgt tccattatct gtaatgattg ataatgttgt ttattctgat gcggatttga
    18901 aagaagaagg taaatttctt cagttgatgc aagaaagtaa gaatcttccg aaaacaagtc
    18961 agccacctgt aggtgtcttt gctgagattt ttgaagacct atgcaaagat ggtggccaga
    19021 ttcttgctat tcatatgtcc catgctcttt cgggtacggt agaagcagca cgccaaggtg
    19081 ctagcctatc tactgcagat gtgactgttg ttgatagttc cttcactgac caagccctga
    19141 aattccaagt tgttgaggct gcgaagttag ctcaagaagg taaagatatg gaggcaattt
    19201 tatctcatgt agaagaggtt aaaaaccata cagagcttta tattggtgtt tcaactttgg
    19261 aaaatcttgt caaaggtgga cgaattggcc gtgtaactgg cttgttgagc tcccttctca
    19321 atatccgtgt tgtcatgcaa atgaaagacc atgaattgca gccaatggtt aaaggtcgtg
    19381 gaactaaaac atttaaaaaa tggttagatg agttgataac atcgctttct gaacgtgctg
    19441 tagcagagat tggaatttca tattctggta gtgatgattg ggcaaaagag atgaaagaaa
    19501 gcttacaagc ttatgttgaa aagccaattt ctgttttgga aacgggttcc attattcaaa
    19561 ctcacacggg tgagaacgct tgggctattt tgatacgtta ccactcctaa aaaataaata
    19621 aaatgggaag aaatagcgtt tttaacttga cctaaaaggg attttaggat atgattatat
    19681 ttgttaatta gaaattattt ggaggaatca ttaacatggc aaacaaacaa gatttgatcg
    19741 ctaaagtagc agaagctaca gaattgacta agaaagactc agcagcagca gttgaagctg
    19801 tatttgcagc agtagctgac tatcttgcag ctggtgaaaa agttcaattg atcggttttg
    19861 gtaactttga agttcgtgag cgcgcagaac gtaaaggtcg caacccacaa actggtaaag
    19921 aaatgacaat tgcagcttct aaagtaccag cattcaaagc tggtaaagct cttaaagacg
    19981 ctgttaaata atcagtcttt aaaaagccta ttgtatcaag ctttctagct tggtcagtag
    20041 gctttttaat tatgaaatct agtaataaat agagttaaaa agttgaatgt tccg
//
LOCUS       DAVMCG010000036        19926 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVMCG010000036 DAVMCG010000000
VERSION     DAVMCG010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19926
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.037"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            459..1622
                     /locus_tag="VYP66_001561"
     CDS             459..1622
                     /locus_tag="VYP66_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1851095.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRSAYYQDDLTTTYRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1619..2296
                     /locus_tag="VYP66_001562"
     CDS             1619..2296
                     /locus_tag="VYP66_001562"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1851096.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLNFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2286..3140
                     /locus_tag="VYP66_001563"
     CDS             2286..3140
                     /locus_tag="VYP66_001563"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1851097.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNAAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQDQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3159..4226
                     /locus_tag="VYP66_001564"
     CDS             3159..4226
                     /locus_tag="VYP66_001564"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1851098.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4236..5402
                     /gene="aroC"
                     /locus_tag="VYP66_001565"
     CDS             4236..5402
                     /gene="aroC"
                     /locus_tag="VYP66_001565"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1851099.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5412..6515
                     /locus_tag="VYP66_001566"
     CDS             5412..6515
                     /locus_tag="VYP66_001566"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1851100.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSEIILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            6526..6864
                     /locus_tag="VYP66_001567"
     CDS             6526..6864
                     /locus_tag="VYP66_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1851101.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTDY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6956..8239
                     /gene="aroA"
                     /locus_tag="VYP66_001568"
     CDS             6956..8239
                     /gene="aroA"
                     /locus_tag="VYP66_001568"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1851102.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8232..8708
                     /locus_tag="VYP66_001569"
     CDS             8232..8708
                     /locus_tag="VYP66_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1851103.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGESAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8705..9553
                     /gene="pheA"
                     /locus_tag="VYP66_001570"
     CDS             8705..9553
                     /gene="pheA"
                     /locus_tag="VYP66_001570"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1851104.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGTYPIYPISD
                     HGKERR"
     gene            9550..10824
                     /gene="psr"
                     /locus_tag="VYP66_001571"
     CDS             9550..10824
                     /gene="psr"
                     /locus_tag="VYP66_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1851105.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11103..11948
                     /locus_tag="VYP66_001572"
     CDS             11103..11948
                     /locus_tag="VYP66_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1851106.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKKT
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EYNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11938..13041
                     /locus_tag="VYP66_001573"
     CDS             11938..13041
                     /locus_tag="VYP66_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1851107.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEEFLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            13043..14029
                     /locus_tag="VYP66_001574"
     CDS             13043..14029
                     /locus_tag="VYP66_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1851108.1"
                     /translation="METALISVIVPVYNVAQYLEKSIDSIQKQTYQNLEIILVVDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSADQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            14045..15478
                     /locus_tag="VYP66_001575"
     CDS             14045..15478
                     /locus_tag="VYP66_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1851109.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQAEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15507..16541
                     /locus_tag="VYP66_001576"
     CDS             15507..16541
                     /locus_tag="VYP66_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1851110.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16741..17478
                     /gene="mecA"
                     /locus_tag="VYP66_001577"
     CDS             16741..17478
                     /gene="mecA"
                     /locus_tag="VYP66_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1851111.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17629..18915
                     /locus_tag="VYP66_001578"
     CDS             17629..18915
                     /locus_tag="VYP66_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1851112.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18917..19786
                     /locus_tag="VYP66_001579"
     CDS             18917..19786
                     /locus_tag="VYP66_001579"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1851113.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
BASE COUNT         5929 a         3607 c         4532 g         5858 t
ORIGIN      
        1 tagaacatat atttagagtt cgaaatagaa tgatgcaaat aggtgaaatt ttaattattg
       61 ttgcttctat aatattattt attgatagta tattgagttt gtaacaaaag gcttctctat
      121 aaaatcaaat tttccagata tctactgaag ctgatttatt tcttcatctt tcttctacta
      181 cctttgtcac taaatttgac agacacatat tgctgataca acctctctac ctataatctc
      241 acagttaacc tgaggctagt ttcatagttt gctatttgat tttcgttgat aataaaaaat
      301 gctcctccaa gacggaagag cattttttat tgtgattctt acacatttac ttcctagttt
      361 tgcaggaagt ctagtatacc attttttaaa agaagagtaa aaaagcaagg gtagtttctt
      421 ttttgagaat tgtctaaaag tttgatataa tggtagttat gaatagaata agagtcagca
      481 aaagggttga aaagaagctt gctaaggggc tagttttact agaagccagt gatcttgaga
      541 atgtcaatct taaggatcag gaagtagagg tgcagggtca ggaaggaaac tttcttggga
      601 ctgcctacct ttctcagcaa aacaagggct tgggctggtt tgtcagcaaa gacaaggtgg
      661 ccttcaatca agctttcttt gaaacgttgt ttagaaaagc caaagaaaag agaagcgcct
      721 actatcaaga tgatttaaca actacctatc gtctctttaa tcaagaggga gatggctttg
      781 ggggtctgac agtggacctt tatggcgact acgccgtctt ttcttggtat aactcttatg
      841 tttatcagat tcgtcagact atatcagaag cctttagaca ggttttccct gaggttttag
      901 gggcttatga gaaaattcgc tttaagggtt tggactatga atctgcccat gtttatggtc
      961 aagaagcacc tgactttttc actgttttag aaaatggtgt cctgtatcaa gtctttatga
     1021 atgatggctt gatgacagga attttcctag accagcatga ggttcgcggt agtttagttg
     1081 acggcttggc tatgggtaaa tccttactca atatgttttc ctacacagcg gctttttcag
     1141 tagctgcggc catgggagga gctagccaga caacttctgt tgatctagcc aaacgttcac
     1201 gagaattgtc tcaagcgcat tttcaggcaa atgggctcag cacagacgag catcgtttta
     1261 tagtcatgga tgtctttgag tatttcaaat atgccaaacg caaagacttg acctacgatg
     1321 tgattgtcct agatccgcct agctttgctc ggaataaaaa acaaactttc tctgtggcca
     1381 aggattatca caagttgatt tcccagagtc ttgagatttt aaatccggga gggattatca
     1441 ttgccagtac caatgctgcc aatgtttccc gtcagaaatt tacagaacaa attgataaag
     1501 gctttgcagg aagaagttac cagattttaa acaaatatgg tcttccagca gattttgcct
     1561 ataataaaaa agatgaaagt agtaattacc tcaaggtgat tagtatgaag gttagtaaat
     1621 gaaattaatc gtttcagtaa tgccaagaag tttagaggag gctcaggctc tggatgccac
     1681 gaggtacctg gatgccgaca tcattgaatg gcgtgccgac tatctgccta aagaagcgat
     1741 tttgcaggta gctccagcca tttttgaaaa attcgcaggc cgtgagttgg ttttcacgct
     1801 acgaactcgc tccgaaggtg gagaaatcga cctttctcca gaagagtata tccatctaat
     1861 caaggaagtt gcgcaactct atcaaccaga ctatattgat tttgagtact atagctacaa
     1921 ggatgttttt gaggaaatgc tgaacttccc aaatcttgtt ttgagttacc ataatttcca
     1981 agaaacacct gagaacatga tggaaatctt gtcagagttg acgatcctaa atccaaaact
     2041 tgttaaggtt gcggtgatgg ctcacacgga gcaggatgtc ttagacttga tgaactatac
     2101 acgaggcttt aaaaccctca atcctgaaca ggaatatgtg accatttcta tgggtaaggt
     2161 gggcaaggtc tctcgtatca ctgcggatgt gactggttcg agttggtctt ttgccagtct
     2221 ggatgaggtt agtgcccctg ggcagatttc tctagctagc atgaaaaaaa tcagggagat
     2281 tttggatgaa gcttgatggc tatacacgtt tagctgcagt tgttgccaat cctattaagc
     2341 attctatttc tcccttcatc cacaatagag cctttgaggc gacagctacc aacgctgctt
     2401 acgtggcttg ggagattgaa gcgagtgact tggcagaaac agtggccaat attcgtcgct
     2461 accagatgtt tggcatcaat ctgtccatgc cctataagga gcaggtgatt ccttatttgg
     2521 atgagctgag cgatgaagcg cgcttgattg gtgcggttaa tacggttgtc aatgagaatg
     2581 gcaatttaat tggatataat acagatggca agggattttt taagtgcttg ccttctttta
     2641 caatttcagg taaaaagatg accctgctgg gtgcaggtgg tgcggctaaa tcaatcttgg
     2701 cacaggctat tttggatggc gtcagtcaga tttcggtctt tgttcgttcc gtttctatgg
     2761 aaaaaacaag accttaccta gacaagttac aggatcagac aggttttaaa gtggatttgt
     2821 gtgctttaga atatgtttct gaactgcaag caaggattgc cgagtcggat ttgctagtta
     2881 atgccaccag tgtgggcatg gatggccaat cctctcctgt tcctgaaaac atagtcttac
     2941 cagaaactct tttagttgca gatatcatat accaaccctt tgaaacaccg tttttgaaat
     3001 gggctagaag tcagggcaat ccagcagtca atggtctggg aatgttgctc tatcaagctg
     3061 cagaagcttt tcaactgtgg acaggcaagg aaatgccgac agaagagatt tggcagtctt
     3121 taacagaaaa ataccaataa agaaagggag actctcctat gaaaatcaga atcgatattc
     3181 ctcaccatcc ttatgatatt cagattgaaa aaggttgtat ggcccaggct ggtcagtggt
     3241 tgcgagaact ctggcaaccg caaaaggtag tcattgtgac agataaccat gtagcctctc
     3301 tctatgcaga gaaggtcaag ctcagcctag aagatgctgg ttttcaggta gctgtttttg
     3361 atttcttaga aggtgaagaa agaaagaatt taactactgt tcagaaagtc tatgaatttc
     3421 tagtcaagca aggtctgact cgtagcgatg gaatcgttgc tcttggtggt ggcgttgttg
     3481 gggacctggc tggatttgta gcctctacct atatgcgggg tattcacttt gttcagattc
     3541 cgactagttt gacagctcag gttgattctt ctatcggtgg aaagacaggc gttaatacac
     3601 catttgctaa aaatatggtg gggacctttg cccaaccaga tggggttctg attgatccac
     3661 ttgttcttga aaccctcgga aaaagagagt tgattgaagg gatgggtgaa gttatcaagt
     3721 atggcttgat tgaggatcca gaactgtggg ctctcttgac gggactgaat ggttctgttg
     3781 agagtatttt ggaacatgca gagaccttga ttgaacattc ttgtcaggtg aagcgcaaga
     3841 tggtggttga agatgagttg gacaatggta ttcgtcttta cctcaatttt ggccacacta
     3901 ttggccatgc catcgaagcg actgccggtt atggcaaggt catgcatgga gaggctgttg
     3961 ccatgggaat ggtacagatt tccaaggttg ctgaggaaaa aggcctcatg ccagctggca
     4021 ttacccaatc tatcacagag atgtgtcaga aattcggttt gcctgttgac tatgaaaatt
     4081 gggaagttga caagctttat caggctctta ctcatgacaa gaaagcgcgt ggtaacacct
     4141 tgaaattggt cttggtgcca gagcttggtt cagcgaccat tcacccagtt tctctggaag
     4201 agatgaaaga ctacttggta aaataaggag agtgtatgag atatttaact gcaggagaat
     4261 cacacggccc ccgtctaaca gctattattg agggaattcc agctggactt ccattgacag
     4321 ctgaggatat caatgaggac cttagacgcc gtcagggtgg ctacggtcgt ggtggtcgta
     4381 tgaagattga gaatgaccag gttgtcttta cttcgggcgt tcgccacggg aagacgacag
     4441 gggcgcctat tactatggat gtcatcaata aggaccacca gaaatggctg gacatcatgt
     4501 ctgcggagga cattgaagac cgccttaaaa gcaagcggaa aattactcat cctcgcccag
     4561 gtcatgccga tttggttggg gggattaagt accgttttga tgatttgcga aattctttgg
     4621 agcgttcatc agctcgtgaa accaccatgc gggtggcagt tggtgcagta gccaaacgcc
     4681 tcttggctga gctggatatg gagattgcca accatgtcgt ggtctttggt ggcaaggaaa
     4741 tcgatgttcc tgaaaatctg acagtcgctg aaattaagca aagagctgcc cagtctgaag
     4801 tttctattgt caaccaagaa cgagaacagg aaatcaagga ctatattgac caaatcaaac
     4861 gtgatggtga taccatcggt ggggttgtgg agacagtcgt cggaggcgtt ccagttggtc
     4921 ttggttccta tgtccaatgg gatagaaaat tggatgcaag attggctcaa gctgttgtct
     4981 ctatcaatgc ctttaaaggg gtggaatttg gtcttggctt tgaggctggt tatcgtaaag
     5041 gcagccaagt tatggatgaa attctctggt ctaaagaaga cggttatact cgccgtacca
     5101 ataatctagg tggttttgaa ggtggtatga ctaatgggca acccatcgtt gttcgtgggg
     5161 tcatgaaacc cattcctact ctttataaac ctcttatgag tgtggatatc gaaacccacg
     5221 aaccttacaa ggcaaccgtg gagagaagtg atccgactgc tcttccagct gcaggaatgg
     5281 tcatggaagc agttgtagca acggttctgg cgcaagaaat cctcgaaaaa ttctcatcag
     5341 ataatcttga ggaactaaaa gaagcggtag ccaaacaccg agactataca aagaactatt
     5401 aaggagttcc tatggcaaaa acaatctata tcgcaggtct tgggttgatt ggagcctcta
     5461 tggcacttgg tatcaaacgc gatcatccag attatgaaat tttaggttat aatcgtagtc
     5521 aagcttcgag agatatcgcc ttgaaagaag gtatgattga ccgtgcaacg gatgattttg
     5581 ctagttttgc tcctttggca gatgtcatta tcctcagctt gccaatcaaa caaactattg
     5641 ctttcattaa ggagttggcc aatttggatt tgcgagaagg cgttattatt tcagatgctg
     5701 gttcgaccaa gtcaaccatt gtggatgcgg cggagcagta tttggctggc aagtctgttc
     5761 gctttgtcgg ggcccatccc atggctggta gtcacaagac aggggctgct tcggcagatg
     5821 tcaatctttt tgaaaatgcc tattatatct ttacaccttc aagcctgaca agtcaggaca
     5881 cgcttaagga aatgaaggat ctgctttcag gtcttcatgc tcgttttatc gagattgatg
     5941 ccaaggagca tgatcgtgtc acttctcaga ttagccattt tcctcatatt ttggcttcta
     6001 gtctcatgga gcagactgcg gtctatgctc aagagcatga gatggcaagg cgctttgcgg
     6061 caggtggttt tcgagatatg acccgaattg cggaaagcga gccaggaatg tggacctcca
     6121 ttctcttgtc caatagcgag atcattctgg atagaattga ggatttcaag gaacgtttgg
     6181 aagcgattgg tcaggccatt agtaagggag atgaagagca aatttggaac ttttttaacc
     6241 aagcgcgtga acaacgccag accatggaaa tccataagcg tggtggtgtg gatagctctt
     6301 acgacctcta tgttgacgtt cctgatgaag aagatgtcat cctgcggatt ttggaactgc
     6361 tacgtggaac ttccttggtt aatatccaca tcaacgagga aaatcgtgag gatattcacg
     6421 gaatcctaca aatttcattt aaaaatgctc aagacttgga aagagctgag catctcataa
     6481 cagaaaatac tgactataca gtcgtcatca aataaggaga agaacatgtc aaatatttac
     6541 gatagtgcaa acgaactcag tcgcggtcta cgcggattac cagaatacaa ggctgttaaa
     6601 gcagctaaag atgcgattgc agcagatgct gaggcaagca aaatctttac agattatctt
     6661 gcctttcaag aggaaattca aaaactagca cagacaggtc aaatgccaga tgcgtccttc
     6721 caagctaaga tggaaggctt tggtaaacag attcaaggaa atagcctctt gtcagaattc
     6781 tttaccaagc aacaacaatt ggccatttac ctttctgata ttgaaaaaat tgtttttgaa
     6841 ccagtttcag aattgctgaa ataagaaaag aactatccta aagtcaggaa tttttaagga
     6901 atttctggct ttttatgata aaataggtaa aagtattgca agtatgaggt ccagtatgaa
     6961 actaaaaaca aacattcgcc atttacatgg tagtatccgc gtcccaggtg acaagtctat
     7021 cagccaccgt tccattatct ttggaagttt ggctgagggt gagaccaagg tttatgatat
     7081 tctgcgaggt gaagacgttc tttcgaccat gcaggttttt cgtgaccttg gtgttgaaat
     7141 tgaggataaa gatggggtta ttaccattca aggtgtaggc atggctggct taaaagcgcc
     7201 acaaaatgcc cttaatatgg gaaattctgg cacctcgatt cgcctgattt caggtgtcct
     7261 tgctggtgca gatttcgaag tagagatgtt tggagatgat agtctttcca aacgtcctat
     7321 ggaccgtgtg acccttccac tgaaaaaaat gggcgtcagc atttcagggc aaactgaacg
     7381 agacttgcct ccccttcgct taaaagggac gaaaaaccta agacctattc attatgagtt
     7441 gccaattgcc tctgcccaag tcaagtcagc cttgatgttt gcagccttac aagctaaggg
     7501 ggagtcagtt attatcgaaa aagagtacac ccgtaatcat actgaagata tgttgcaaca
     7561 atttggtggt catttaagtg tggatggtaa gaaaatcaca gtccaggggc cacaaaaatt
     7621 gacaggacag aaggtggtcg taccaggaga tatttccagt gcagcctttt ggttagtcgc
     7681 aggtttgatt gctccaaatt ctcgtctagt gctgcagaat gtggggatca acgaaactcg
     7741 caccggtatt attgatgtca ttcgtgccat gggtggaaaa ttggaaataa ctgaaatcga
     7801 tccagtcgct aaatctgcta ccttgattgt tgagtcttct gacttgaaag gaacagagat
     7861 tggtggcgct ttgattccac gattgattga tgaattgccc attattgccc tgcttgcgac
     7921 tcaagcccaa ggtgtaacag ttatcaagga tgctgaggag ctcaaggtca aggaaacaga
     7981 ccgtattcag gttgtggcag acgccttaaa tagtatggga gcagatatta ctcctacggc
     8041 agatgggatg attatcaaag gaaaatcagc tcttcacggt gctagagtca atacgtttgg
     8101 tgaccaccgt atcggcatga tgacagctat cgcagccctc ttggttgcag atggagaggt
     8161 ggagcttgac cgtgcagaag ccatcaatac cagctatcct agtttctttg atgatttgga
     8221 gagcttgatt catggctaag gtgttattag ggtttatggg ggctggaaaa tcgactattg
     8281 caagaggctt ggaccctaat taccttgata tggatgctct gattgagaag cgcctaggta
     8341 tgtccattgc gaattttttc gctgaaaagg gagaatcagc ctttcgtcag gtagaatcag
     8401 aagtcctagc tgatttacta caaacagacc aagtcgtgtc aactggagga ggagtggtta
     8461 tttctcagag aaatcgtgac ttactcaaga ctaatacaga taacatctac ctgaaagcag
     8521 attttgaaac cctctaccaa cgtatcgcag ctgataagga caatcagcga ccgctttttc
     8581 taaataatag caaggaagaa ctagtagcta tttttcaaga aagacaggct tggtatgagg
     8641 aagtggctag tcgggttttg gatgtgacca agctaagccc agaggaaatt atagaggaac
     8701 taagatgaaa attgcttatc taggtcccaa gggatcattt tcacaccacg ttgtgcagac
     8761 agcttttcct catgaggaat tgcaggcttt tgccaacatt acagatgtca tcaaggctta
     8821 tgagcaagga ttagtggact attctgtggt gccagttgaa aactctattg agggtagtgt
     8881 tcatgaaacc ttggactatc tttttcatca ggctcacatc caagcagtag cagaaatcgt
     8941 tcagcctatt catcagcagt tgatggtggt tccaggccat actaagattg aaaagatttt
     9001 ttcacatcca caggccttgg ctcaaggaaa gaaattcatc gatgaacaat atccagaggc
     9061 tcaaatcgag gtaacagcta gtacagctta tgcggcccgt tttatttccg aacatccaga
     9121 tcagcccttt gcagcagttg cacctagaag ttctgctgaa gaatatggat tggaactgat
     9181 tgccgaggat attcaggaaa tggaagccaa tttcacccgt ttctgggttc taggagctga
     9241 aaagcctagt attcccttgc aagcacaaac tgaaaagatg agtttggcct tgacattacc
     9301 tgacaacctt ccaggtgcac tttataaggc cctgtcgacc tttgcttggc gaggaattga
     9361 cttgacaaaa attgaaagtc gtccactcaa gacagcactg ggtgaatact ttttcattat
     9421 cgatgtggat tataccgata aggacttggt ccactttgcc caaaaagaat tagaagcgat
     9481 tggaatccag tataaaattc tgggtaccta tcctatttat ccaatatcag accatggaaa
     9541 ggagagaaga tgagtaaaga aaatccctta agtcatcatg agcagttgcg ttatgattat
     9601 ttgctaaaaa atattcacta tctcaatgag agagaaaaaa atgagtttgc ctatttgcaa
     9661 gaaaagctaa ctcttgctag gggaaatagt agctctagct tggaacaaga aagagaagag
     9721 caggttgact taccaagcta tgcgaaccgg agtcgctcac aatccaaatc acaagcactc
     9781 tctttccctc caaaaaagaa aagacggaag ctccgtctta aacgaatttt tatggtgatt
     9841 ttttcacttt tggtctgtgt ggctttggcc atggtattca tgtttttgcg tggttaccaa
     9901 gatgctagcg caaagaaaac tgctgatgcc cgggcagctc aagtagaagt ctttaatggt
     9961 caggacacta gagatggagt taatatttta atcatgggta ctgatggtcg aatcggccag
    10021 aacagtgttg agacacgaac tgactctatt atggtattaa atgtcggggg ctcagataag
    10081 aaaatgaagc tagtcagttt catgcgtgat aatttggtct atatagatgg ttatagtcaa
    10141 gtgattaatg gtagaaaaca gacagataac aagttaaacg tagcctacga gttaggagaa
    10201 caagaggggc aaaaaggggc agaaatggtt cgccaagtct tgaaagataa ttttgacttg
    10261 gacattaagt actacgcctt ggttgatttc caggcctttg ccacagcgat tgacacgctt
    10321 ttccctgatg gggtgacgat tgatgctcaa ttttcaacat tgaatgggcg tcccctaaca
    10381 gaagctacag tcggagatga tttatatgct accgagactg agtctccaac ccaaaccatt
    10441 aaagtcggaa aacagcagat gaatggctcg accctgctca attatgctcg tttccgtgat
    10501 gatgatgagg cggattacgg ccgtacaaaa agacagcaac aagttttaac agcaatttta
    10561 gagcaaatta aagatcccac taaacttttc actggttctg aagctcttgg aaaggttttt
    10621 gctatgacct caaccaacgt accctatact ttcctcctaa caaacggttt atctgttttg
    10681 gatggagcaa aaaatggtat tgaaaaattg acgattccag aactgggtga ctgggtagat
    10741 gcctatgatg tttatggagg cttgggcttg ctggttgatc aaaacaaata tcaaaccaag
    10801 ctcgctcaaa tgggcttgag ataagataat actcaatgaa aattaaagtg caaactagga
    10861 agctagccgc aggctgctaa aaacacagtt ttgaggttgt agataagact gacgaagtca
    10921 gttacctata cctacggcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat
    10981 aagacagaaa aatcaaagtt tgatagctat ttggatagca gtcaggcttt gattttttac
    11041 agtctgcaat agattttcac tccttgtttg tggtataatg aaacgatacg atagaaagaa
    11101 taatgaacaa tatgactgat ttaaaagcaa ttcaggctcg tagtctggag atggctgaat
    11161 attttgtggc cttttgtaaa gaacatgatt tgctctgtta tctctgtggc ggaggcgcta
    11221 ttggtgccct tcgaaacaag ggatttattc cttgggacga cgacctagac ttttttatgc
    11281 ctcgtaaaga ttatgagaaa ttagcagaat tatggcctcg ttatgcagat gaacgttatt
    11341 tcttgtcaaa gagtcacaag aattttgttg atcgtaatct ttttattacc attcgtgaca
    11401 agaaaaccac ctgtatcaag ccttatcagc aggatttgga tttgccacat ggtctggcct
    11461 tggatgtttt gcctttggat tattatccga aaaatccagc tgagcggaaa aaacaggttc
    11521 gttgggcctt gatttattca ctcttttgtg cgcaaactat tccagaaaag catggtgctc
    11581 tcatgaaatg gggaagtcgc attttactgg gtttgactcc aaaatctctc cgttatcgca
    11641 tctggaaaaa agctgagaaa gaaatgacta agtatgattt ggctgattgt gatggcatta
    11701 cagaattatg ctcaggtcct ggctacatga gaaacaagta cccaatcaca tcttttgaat
    11761 acaatctttt cttgccattt gaaggaacag agatgcctat tccaatcggc tatgatgtct
    11821 atctcagaac tgcttttggg gattatatga cgcctccacc agcagacaag caggtaccgc
    11881 atcatgatgc tgtcatcgct gatatggata agtcttatac agaatacaag ggagaatatg
    11941 gtggctaaga aaaaaatctt attttttatg tggtcttttt ctcttggagg tggtgcagag
    12001 aagattctat caaccattgt ttcaaatctg gatccagaaa agtatgatat tgatattctt
    12061 gaaatggagc actttgacaa gggatatgaa tctgttccaa agcatgtacg cattttaaaa
    12121 tcccttcaag attatcgcca aaccagatgg ttacgagctt ttttgtggag aatgagaatt
    12181 tattttccaa gactggctcg tcgtttgctt gtaaaagatg attatgatgt tgaagtttct
    12241 tttaccatta tgaatccacc actgttgttc tctaaaagaa gagaagtcaa gaagatatct
    12301 tggattcatg gaagtattga agaatttctt aaggatagct ctaaaagaga atcacataga
    12361 agccagttgg atgctgcgaa tacaattgta gggatttcaa aaaagaccag caattctatc
    12421 aaggaagttt atccagatta tgcttctaaa ttacagacaa tctacaatgg atatgatttt
    12481 cagactattc tagaaaaatc tcaagagaag atcgatatcg agattgctcc tcaaagtatc
    12541 tgtactatcg gacggattga ggaaaataag ggttctgacc gtgtagtgga agtgatacga
    12601 ttattacacc aagagggaaa aaactatcat ctctatttta tcggggctgg tgatatggaa
    12661 gaggaactga aaaaacgagt caaagagtat gggattgagg actatgtaca tttccttggt
    12721 tatcaaaaaa atccttatca gtatctatct cagacgaaag ttctcttgtc tatgtctaaa
    12781 caagaaggtt ttcctggagt gtatgtggag gccttgagtc tgggactccc ttttatctct
    12841 acggacgttg gaggggctga ggaattatcc caagaaggac gatttggaca aatcattgag
    12901 agcaatcaag aggcagctca ggcgattact aattacatga cttctgcctc aaactttgat
    12961 gtcgatgagg ctagccaatt cattcaacaa tttacaatta caaaacaaat cgaacaagta
    13021 gaaaaactat tagaggagta gcatggaaac tgcattaatt agtgtgattg tgccagtcta
    13081 taatgtggcg cagtacctag aaaaatcgat agattccatt cagaagcaga cctatcaaaa
    13141 tctggaaatt attcttgttg ttgatggtgc aacagatgaa agtggtcgct tgtgtgattc
    13201 aatcgctgaa caagatgaca gggtgtcagt gcttcataaa aagaacgaag gattgtcgca
    13261 agcacgaaat gatgggatga agcaggctca cggggattat ctgattttta ttgactcaga
    13321 tgattatatc catccagaaa tgattcagag cttatatgag caattagttc aagaagatgc
    13381 ggatgtttca agctgtggtg tcatgaatgt ctatgctaat gatgaaagcc cacagtcagc
    13441 cgatcaggat gactattttg tctgtgattc tcaaacattt ctaaaggaat acctcatagg
    13501 tgaaaaaata cctgggacga tttgcaataa gctaatcaag agacagattg caactgccct
    13561 atcctttcct aaggggttga tttacgaaga tgcctattac cattttgatt taatcaagtt
    13621 ggccaagaag tatgtggtta atactaaacc ctattattac tatttccata gaggggatag
    13681 tattacgacc aaaccctatg cagagaagga tttagcctat attgatatct accaaaagtt
    13741 ttataatgaa gttgtgaaaa actatcctga cttgaaagag gtcgcttttt tcagattggc
    13801 ctatgcccac ttctttattc tggataagat gttgctagat gatcagtata aacagtttga
    13861 agcctattct cagattcatc gttttttaaa aggccatgcc tttgctattt ctaggaatcc
    13921 aattttccgt aaggggagaa gaattagtgc tttggcccta ttcataaata tttccttata
    13981 tcgattctta ttactgaaaa atattgaaaa atctaaaaaa ttacattaga acgggggtga
    14041 ccaagtgatt gatgggaaac gattattatt tagtttgacc atagtcagtt atgccttgac
    14101 gctagtaagt ggaattgtgt atctgtttaa taataataat gttagcttac tttctacttt
    14161 attgttcttg ttggttagta gcttaattgc ttgttggaat gatatcaagt attacttaat
    14221 ccattttatt ttctatttaa ccatttttgt atttctggta tcaagaccga ccattgatta
    14281 ttttagggat ggtgctttgg atacctatca tccaatagcc tatcgttttg cctttatagt
    14341 tgtcatggtt tcgattctgg gcttgaccac aggaggcatt ctggctcgtt acttcatagc
    14401 taggaagaaa ataaaagtag caaatatagg aaattctcta aaagaggttt atatcaagcg
    14461 gttacgcttt gtatcactag gagtttttct tctaacttat cctttctatt tcattcggtt
    14521 atttgaacgg ctcttgtatc gtttgcagac ttcctactat gcctactatg caaattttga
    14581 aagtaaactg ccttatttta cctacatttt gtctaccttt acggtctatg caatgtgtat
    14641 gtatctggca accaagccaa agaaattgca ggccacagca gtgcttgtct cctttattgc
    14701 agctaacact attcatttgg caattgggac acgaaatccc tttattttaa gtattttatt
    14761 tgcttttgtt tattacttta tgcgggagca agctgaaaaa ggaaaatgga ttgggtttaa
    14821 agaaaagtta gcgatttttg taggttctcc tattctcatg ttagcgatgg gagtactcaa
    14881 ttatgtacgg gataatgtcc aagtttccca tacaggtttc tgggatatct tacttgactt
    14941 tatctataaa caagggacta gttttggtgt tctggctcga ggttttctat ttaacagtag
    15001 cctcccttac cgagatttcc gtaattttac ttttggtcct gttcttgatt attttgcaag
    15061 ggggagtttg ggagccattt tcggaggaaa agcctttgaa catacaacca atagtgtgga
    15121 actagctatt gatagtaata gttatgccca caatctatcc tatcttgtct tgaacaagga
    15181 atacttgaaa gggcatggta tcggaagtag ttatatcatg gagttgtata ccgactatgg
    15241 tatgattgga gtctttctgc ttagtttctt actcggcgta ttatttatag ccatgctgca
    15301 agtagcctat cgctcaagga caatcctatt tgctttatcc ctactcatct tgaataatct
    15361 attctttatg ccaagaagca gcttttcaga aagtttcttc aatttattta caatgcaatt
    15421 ctggggaatt gttcttgtga ttatatttgt agcaaaaatg cttacaaagg aaaactagta
    15481 tctactaaac aaaggagaaa aaaatcatgt ttgaacatta ttcagtagct gatttgtttg
    15541 caaatcttta taaaaagcga aaagcaaata ttttagctct catcgcttta tttgctctca
    15601 ttgctgtacc atttacaatt aaagcagtta ggaataaaaa cactgtcaaa gatacaacaa
    15661 gttattcaac ttatcttatc tataaaatca ctcctccaaa agagtcggcc aaaacgattt
    15721 tgaatcatca aattggtggt tatagtgatt tttatgggaa attgattgat ggtaatttga
    15781 atggagctta tcttttcaat gatgtagaac ccagtgagtt gaaaaaaatt gccagtgaat
    15841 tagacacgac agaaacaacc ttgaaaaatt caacgaatga ctattggtgg aaaaaattga
    15901 ccgtctacta tatgattgac gatgcagggg ttggtgtgaa aattttgaca tcaagtaaag
    15961 atgccaatga cttgttagag aaaaaaattg atgggttgat tgagaaattt aaacatgcct
    16021 atgcaaatgt gaaaattgaa aaactggaaa ccatcaactc taaagaattg aacgcaaatg
    16081 gtgaaacagc gcttggctta aatgtgaaaa atctgattct tcgtttagtt gttattggag
    16141 tggtttgtgt gattttggtt gtgatgggaa atgtgttagt ttatctcttt aatccaacaa
    16201 tcaatagagt aggtgatttt tctcagtatc aaattgattt tgtaacagag attacaacaa
    16261 ttgctaacct agcagatgtt ttgtcataca aaaatactgg acaggaattg accatcgtta
    16321 gctcaaataa agctatccta gataaattga aacagagtca agaagcttta aaaggaatgc
    16381 attttgtaga tttacaggat gtatcatctc ttttggaaag agatacagtc cttcttgttg
    16441 aagagtacgg agtgactcgt tataagaaat ttgagcaaag tcttcaaatt ctcagaaact
    16501 taaatcgttc tatccttggt gtagcaacct ttaaattata agtattctga tgtataaggt
    16561 cttcaaaatc ggctaagagc tgattttgaa ggctttttct atctgtctgc agaaattttc
    16621 ttttggagtc tcctatagaa agaccctagg gaaaatctat ccgtatagag gagccttctt
    16681 ttgataaaat cgtaaaaatc tagtataata gatagaactg aaagtatgag gttactagca
    16741 atgaaaatga aacaaattag tgatacaact ttaaaaatca cgatgtcttt agaggatttg
    16801 atggatcgtg gaatggagat tgctgacttt ctcgttcctc aagaaaaaac agaagagttc
    16861 ttttatgcta tcttggatga gctagagatg cctgatagct ttctggatac aggcatgttg
    16921 agcttccgtg tgactccaaa acctgataag gtagatgtct ttgtgaccaa gtcaaagatt
    16981 gaccaaaatc tagattttga agacttatcg gatttgccag atatggaaga attggctcaa
    17041 atgtctccag atgaatttat caaaaccctg gaaaaaagca tcgcagacaa aaccaaggat
    17101 gatatcgaag ccattcaatc tcttgagcaa gttgaagcca aggaagaaga acaagagcag
    17161 gctgaacaag aagctgagag taagaaagaa ccttacatct actacatcct ttcttttgct
    17221 aagttggctg acttggtagc ttttgccaag acagtgactt ttgaaatgga aacttctgaa
    17281 ctctacaaaa tgaacgagcg ctattatttg accattttag tggatattga aaatcatcca
    17341 agcccatatc cagcttggct gttggcccgt atgcgcgagt ttgcagacga tagtgatatc
    17401 agtcgctcag tcttacaaga gtatggtcaa gtcttgatga gtcacgatgc agtgctcaat
    17461 ctgcaaaaaa tcggctaatc ttttctggaa agctattttc agattttaag aagagcgaat
    17521 cgtctgattc gttttttctt tttatactga aatagtgatt tactataata ggaattttca
    17581 caaaattctg ttataatggc tatattagaa aatttcgagg agataaagat gacagttaaa
    17641 attgctttac taggatttgg taccgttgca agtggtgtgc ctttcctcct aaaggaaaat
    17701 ggaggaaaaa tcaatcaatc agcacattca gatatcaaag ttgctaaggt attggtcaag
    17761 gatgaagatg aaaaaaatcg cttgcttgca gcagggaatg actttaactt tgtaaccaat
    17821 gtggatgata ttttatcaga ccaggatatt actatcgtag tggaattgat ggggcgtatt
    17881 gagcctgcta aaacctttat cactcgtgcc ttggaagctg gaaaacacgt tgttactgct
    17941 aacaaggacc ttttagctgt ccatggcgca gaattgctag aaatcgctca agctaacaag
    18001 gtagcacttt actacgaagc agcagttgct ggtgggattc caattcttcg tactttagca
    18061 aattccttgg cttctgataa aattacgcgc gtgcttggag tagtcaacgg aacttccaac
    18121 ttcatggtga ccaagatggt ggaagaaggc tggtcttacg atgatgctct tgcggaagca
    18181 caacgtctag gatttgcaga aagcgatccg acgaatgacg tagatgggat tgatgcagcc
    18241 tacaagatgg ttattttgag ccaatttgcc tttggcatga agattgcctt tgatgatgta
    18301 gcccacaagg gaatccgcaa tatcacacca gaagacgtag ctgtagctca agagcttggt
    18361 tacgtagtga aattggttgg ttctattgag gaaacttctt caggtattgc tgcagaagtg
    18421 actccaacct tcctacctaa agcgcaccca cttgctagtg tgaatggcgt aatgaacgct
    18481 gtctttgtag aatctatcgg tattggtgag tctatgtact acggaccagg tgcgggtcaa
    18541 aaaccaactg caacaagtgt tgtagctgat attgtccgta tcgttcgtcg tttgaatgat
    18601 ggtactattg gcaaagactt caatgaatat agccgtgact tggtcttggc aaatcctgaa
    18661 gatgtcaaag caaactacta tttctcaatc ttggctctag actcaaaagg tcaggtcttg
    18721 aagttggctg aaatcttcaa tgctcaagat atttccttta agcaaatcct tcaagatggc
    18781 aaagagggtg acaaggcgcg tgtcgttatc atcacacaca agattaataa agcccagctt
    18841 gaaaatgtct cagctgaatt gaagaaggtt tcagaattcg acctcttgaa taccttcaag
    18901 gtgctaggag aataagatga agattattgt acctgcaacc agtgccaata tcgggccagg
    18961 ttttgactcg gtcggtgtag ctgtaaccaa gtatcttcaa attgaggtct gcgaagaacg
    19021 agatgagtgg ctgattgaac accagattgg caaatggatt ccacatgacg agcgtaatct
    19081 cttgcttaaa atcgctttgc aaattgtacc agacttgcaa ccaagacgct tgaaaatgac
    19141 cagtgatgtc cctttggcgc gcggtttggg ttcttccagc tcggttatcg ttgctgggat
    19201 tgaactagcc aaccaactgg gtcaactcaa cttatcagac catgaaaaat tgcagttagc
    19261 gaccaagatt gaagggcatc ctgacaatgt ggctccagcc atttatggta atctcgttat
    19321 tgcaagttct gttgaagggc aagtctctgc tatcgtagca gactttccag agtgtgattt
    19381 tctagcttac attccaaact atgaattacg tactcgcgac agccgtagtg tcttgcctaa
    19441 aaaattgtct tataaggaag ctgttgctgc aagttctatc gccaatgtag cggttgctgc
    19501 cttgttggca ggagacatgg tgaccgctgg gcaagcaatc gagggagacc tcttccatga
    19561 gcgctatcgt caggacttgg taagagaatt tgcgatgatt aagcaagtga ccaaagaaaa
    19621 tggggcctat gcaacctacc tttctggtgc tgggccgaca gttatggttc tggcttctca
    19681 tgacaagatg ccaacaatta aggcagaatt ggaaaagcaa cctttcaaag gaaaactgca
    19741 tgacttgaga gttgataccc aaggtgtccg tgtagaagca aaataaagaa tagaagatag
    19801 gatggggaaa ctcttgacca gagggtttca tatccttttt gtgaaaagaa gtttatactc
    19861 aatgaaaatc aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac agtgttttga
    19921 ggttgt
//
LOCUS       DAVMCG010000037        19674 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVMCG010000037 DAVMCG010000000
VERSION     DAVMCG010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.038"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..432
                     /locus_tag="VYP66_001580"
                     /pseudo
     CDS             1..432
                     /locus_tag="VYP66_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(549..896)
                     /locus_tag="VYP66_001581"
     CDS             complement(549..896)
                     /locus_tag="VYP66_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1851114.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1007..2782)
                     /gene="spxB"
                     /locus_tag="VYP66_001582"
     CDS             complement(1007..2782)
                     /gene="spxB"
                     /locus_tag="VYP66_001582"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1851115.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2989..5232)
                     /locus_tag="VYP66_001583"
     CDS             complement(2989..5232)
                     /locus_tag="VYP66_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1851116.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTTIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFRLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5242..5613)
                     /locus_tag="VYP66_001584"
     CDS             complement(5242..5613)
                     /locus_tag="VYP66_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1851117.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5624..6019)
                     /locus_tag="VYP66_001585"
     CDS             complement(5624..6019)
                     /locus_tag="VYP66_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1851118.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     SRLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6203..6301
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6385..7176
                     /gene="thiD"
                     /locus_tag="VYP66_001586"
     CDS             6385..7176
                     /gene="thiD"
                     /locus_tag="VYP66_001586"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1851119.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDAYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLDSVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7387..8019)
                     /locus_tag="VYP66_001587"
     CDS             complement(7387..8019)
                     /locus_tag="VYP66_001587"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1851120.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGAGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8012..8815)
                     /locus_tag="VYP66_001588"
     CDS             complement(8012..8815)
                     /locus_tag="VYP66_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1851121.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVRDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYHG
                     MSFLVTGPKDLVVSKNQVAVLGNGCAELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8815..9339)
                     /gene="thiW"
                     /locus_tag="VYP66_001589"
     CDS             complement(8815..9339)
                     /gene="thiW"
                     /locus_tag="VYP66_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1851122.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9344..10036)
                     /gene="tenA"
                     /locus_tag="VYP66_001590"
     CDS             complement(9344..10036)
                     /gene="tenA"
                     /locus_tag="VYP66_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1851123.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10047..10697)
                     /locus_tag="VYP66_001591"
     CDS             complement(10047..10697)
                     /locus_tag="VYP66_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1851124.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10699..12084)
                     /locus_tag="VYP66_001592"
     CDS             complement(10699..12084)
                     /locus_tag="VYP66_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851125.1"
                     /translation="MGLELRAIQSPIFPEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSPPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTEVASKEVASSPELFHMDRTTCEFGNRSLFSIADFTFYQGISCILGDNGVGKSTF
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRDFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12085..12645)
                     /locus_tag="VYP66_001593"
     CDS             complement(12085..12645)
                     /locus_tag="VYP66_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1851126.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12907..12995)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13204..13833)
                     /locus_tag="VYP66_001594"
     CDS             complement(13204..13833)
                     /locus_tag="VYP66_001594"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1851127.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGVKLMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13835..14617)
                     /gene="thiM"
                     /locus_tag="VYP66_001595"
     CDS             complement(13835..14617)
                     /gene="thiM"
                     /locus_tag="VYP66_001595"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1851128.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            14708..14794
                     /locus_tag="VYP66_001596"
                     /pseudo
     CDS             14708..14794
                     /locus_tag="VYP66_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14944..15612)
                     /locus_tag="VYP66_001597"
     CDS             complement(14944..15612)
                     /locus_tag="VYP66_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1851129.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15827..15915)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16167..17303)
                     /gene="lctO"
                     /locus_tag="VYP66_001598"
     CDS             complement(16167..17303)
                     /gene="lctO"
                     /locus_tag="VYP66_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1851130.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17928..19418)
                     /gene="lysS"
                     /locus_tag="VYP66_001599"
     CDS             complement(17928..19418)
                     /gene="lysS"
                     /locus_tag="VYP66_001599"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1851131.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19546..>19674)
                     /locus_tag="VYP66_001600"
     CDS             complement(19546..>19674)
                     /locus_tag="VYP66_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1851132.1"
                     /translation="NAEGHVDFINTYDLEPMAQQVISKAAFGYIASGAEDTFTSFQ"
BASE COUNT         5905 a         4303 c         3629 g         5837 t
ORIGIN      
        1 tccatagtca ctatatacga gaatttcgct attgttatgg agctgttgat gccccataca
       61 ggcgaatcat ttttcttaat agctggtgga tgtaatactg agtggatgaa cgccttttta
      121 gaagagcttt cacaagctta tccagatgat tatcttttac tcgttatgga caatgctata
      181 tggcataaat caagtatctt aaagattccg actaatattg gttttgcatt tattcctcca
      241 tacacaccag agatgaaccc cattgaacaa gtgtggaaag agattcgtaa acgtggattt
      301 aagaataaag cctttcgaat tttggaagat gtcatgaatc aactccaaga tgtcatacaa
      361 ggattggaga aggaggtgat aaagtccatc gttaatcgga gatggactag aatgcttttt
      421 gaaagcagat gagtataata tgcaatttct ttatataaaa agaccggatt gctccgatct
      481 ttcaatagtt catattctca atttctattt taaaaatagc taaggttaac gtcaaatgac
      541 tacgcgacct atttcatacg ataaaaatca agcactagac cagcaggtcc ttgaactaat
      601 aaggactctg ttccccaatc ggttacagtt ggtccgtgta aaacctttat accaagctcg
      661 ttcaaccgtt tgtagttctg gtctacatcc tcaacctcga tatgaataat gattcctgac
      721 tgaaagtttt ccaaaggaac caaatgattt tgtgacaaca taaggcagtg actaccaatc
      781 gtaaactgag caaaaccatc atcagcataa tctgcctttt tatccaaaat atgctccaag
      841 tcagcacaga cttggggaac atttgaaacg ataatatcta attgatttaa attcatttac
      901 tctcctccat aaaaagaccg gattgctccg atcttttaaa gttctgctct atgaaaatca
      961 aagaataaag tctacaagtt tcatatttga ttttcggcga gaggaattat ttaattgcgc
     1021 gtgattgcaa tccttcttct tccaagaaga gacggaatgg tacgagttct tctgcttcgt
     1081 atttttcctt gaaggctttg atagcttctt ctgagtgaag ttttggatcc aattcaagta
     1141 cttctactgg aagtggacgg tgttgagtga tgcgagcatc gatgacaaca gttttacctt
     1201 ctttgttcaa tttaacagct tctgcaacaa ctgcatcgat gtcttcgata cggtcaactg
     1261 tgaatccaac agctccttga gcttccgcaa ttttagcgta gtcagcgttt gtgaagtcta
     1321 caccaaacaa gtgtttgttt gtatcttcgt atttgttctt gatgaagccg tactcagcat
     1381 ttgagaagac aaggttgata actggaaggt cgtattgaac gtttgtgata acgtctgggt
     1441 agcacatgtt gaatgctcca tcacccatga tgttccatac ttggcgatct ggattgtctt
     1501 tcttagcagc gataccacca ggaagggcaa tacccattgt cgcaaagagt ggagatgtac
     1561 gccacatgtt cttaggtgtc atgtgaaggt gacgagtaga tgtttgagta gtgttaccta
     1621 cgtcgattga gtagatagcg tcttgatcag catgtttgtt gattgcattg taaacttgat
     1681 acaattgcaa ttcaccctca gttttacctt cgagtttgtt catgtaatca cgccagtttt
     1741 ggttattctt aacgtttgca cgccaccatg gagttgattc aactgggttt actttgtcaa
     1801 ggatagcttt agctgcttga ccagcatcac caaggattga agcgtcaagg gcatgacgtt
     1861 taccaagttt gtaagggtcg atatcaactt ggatgaattt ttcagtgttc ttgaatgctt
     1921 cgtaaacttc agcaaatggg aagtttgaac caaggaaaag aactgtgtct gcttcaaaga
     1981 ccacttcgtt ggctggtttc caaccaacac gataagcaga acctgtcaaa ccttcatagt
     2041 tccattcgaa agcttcaaag tttttaccag ttgtgatgat tggtgctttg attttacgtg
     2101 acaattcagt aatcacttca ccagctttaa caccaccaaa tccagcatag ataactgggc
     2161 gttcagcatt gttcaagatt tcaacagctt tgtcgatttc aacttcgttc aaagcaggag
     2221 cgatgaatga gcgttcgtat gaacctgaac cgtagtatga gttttcgtcg atttcttgga
     2281 aaccgaagtt tactggaatt tcaacaacag ctggaccttt tttagaaatt gcagcacggc
     2341 aggcttcgtc aattactttt ggcaattgct cagcgtaagc tacacgtttg ttgtaaacag
     2401 cgataccgtt gtacattggg ttttggttaa gctcttggaa agcatccatg ttcaattcgt
     2461 taactggacg tgatccaagg atcgctagga atggagtgtt atccatagct gcatcgtaaa
     2521 caccgttaat caagtgagtc gcacctggac cacctgaacc aactgcaacc ccgattgagc
     2581 cgccgaattt agcttgcata accgctgcaa gagcacctgt ctcttcgtgg cgaacttgta
     2641 agaagcggat atctttgtct tcagccaaag cgtccatcaa tgagctgagt gttcctgatg
     2701 ggataccgta gattgtatct acgccccatg ttttcaatac gttaagcatt gctgcagatg
     2761 cagtaatttt cccttgagtc ataatgataa ctctccttca atttttttag atttggagaa
     2821 tacgattaca tagaattgga aacgttctcc aaatttttac tattccactg tatcatattt
     2881 atgctgactt ttctaaaaat ctgctcaaaa ctctctattc tctattctaa tacagttttg
     2941 aaagttctgt catttctgtt ttataacaaa gaaatctagt cattactttt agtctatttt
     3001 actaaaattt aacagaaggg aactggtcag aacagataca gaactaaagg ccatggctag
     3061 acctgccaat tctgggttga gagccagtcc aacacctgaa aagactcctg ctgcaatcgg
     3121 aattccgaca acattgtaga taaaagccca gaaaagattg agtagaattc gatgaaaggt
     3181 tttcttactc atatcaaagg cacgaaccac tcctaaaaga ttattggttg tcaacaccaa
     3241 atctgctgac tcgatggcga tatctgttcc agctcccata gcaatcccca catctgctac
     3301 actaagggca ggagcgtcat tgataccgtc cccaacaaag gctactttcc ctgactgttg
     3361 cagtttatgg atttcatggg ctttttcttc tggcaagacg cctgcaatga cctcttcaat
     3421 tccgatttga tctgcaatag cacgcgccac accagcattg tctcctgtca gcatgactgt
     3481 tcggagacca cgttttttta gctgactgat ggctagctta gcattttcct taggaatatc
     3541 ttgcaaagca agcaagcctt tgatttcatt gtcaacagct aagaacacaa ctgtcttagc
     3601 ttctttttct agttcttcta gtttatcttg ataagtatta gaaatatcca tgccatccag
     3661 cattttagca tttccaagta aaacttgttt tccattgatt cgccctgaaa cacctttccc
     3721 gtgcaaggtc tgaaaatttt caacagtttg aaactcaagt ccagcttcac tcgctcgctt
     3781 aacgatagcc tcagccagtg ggtgttgaga agcatcttcc aaggaggctg ccaacctaaa
     3841 cacttctact tcgtcgccga tgacatctgt taccacaggt ttcccttccg tcaaagtccc
     3901 ggtcttatca aagacaaggg tttgaacttt ctggatttcc tgtaagacag ttccattttt
     3961 gaggagaacc cccatcttgg cactacgtcc tgtccccacc ataagggctg tcggtgttgc
     4021 aagtcccaag gcacaaggac aggcgataat caaaaccgcc actccgtaga gaagagagga
     4081 cacaaagcta gctccaagca caaccacact atccctgagc aagacgaacc aaacccaaaa
     4141 ggtcatgatt cctaaaatga caactactgg gacaaaaatc cctgaaatct tatccgtcaa
     4201 gtcttgaatc ggcgcacgac ttgtctgagc tttcttcaca aaatccacaa tctgagccaa
     4261 aacagtctct gagccaactt tttctgctct aaagacaagc gttccactat gattgatggt
     4321 tgagccaatg acagtatctc caactgtctt gtccacaggc agactctcac ctgtcaccat
     4381 ggattcgtca atactagaga caccttctac tacgacacca tcaacagcaa tcttttcacc
     4441 gggacgcact cgaatcaggt cgcctacctt gacttgttcc aaaggaactt ggacataact
     4501 atcatcactc aagacttctg cggttttagc ttgcaagtcc agtaatttct ccacagcttg
     4561 ggacgtattt tttctcattt tttcctcaaa aactgctccc aaaagaacga aaaagaggat
     4621 aaatccagca ctttcgaagt aaacagggag accagcaaag agagcaacta ggctatagaa
     4681 ataagccact agagttccca gcgcaaccaa ggtatccatg ttggcattgt gctttttaaa
     4741 actggcccaa gcactctgga tatatggctt acctgcaact aacataatag tcgttgttgc
     4801 tagaaaggtt ccccaatgca tgacttgatg actaatgcta cctgtcaaca tcccaatcat
     4861 gagaatcaca agaggcacag taaagatact agtaatccaa aaacgttgca ggagagatag
     4921 agattttcga gtcttctcaa cgactgtata gcttcccttt tgcatcttca tgccacaaga
     4981 aaattcatgt cgccctaatt cttgaggtgt aaaacgaatg actttctcct catctacgcc
     5041 gattggttcc aagatacctt cttcttcaaa cagaatttcc ttataacagt ttgaaggagt
     5101 agcacgatga aaggtaatct cagctggaat tcccttttga agctggatat gggctggatg
     5161 atagcctttt tcagctcgga tacggatttt ttgaatgcca ttttctaagc ttgctttcac
     5221 aatttctgtc atagtctcca cctactctac aatcatcttg ccgtgcatca tgttcatacc
     5281 acaagcaaag ccaaactctc cagcctgctc aggcgtgatt tccactacat actcttcccc
     5341 cattggcagg ttcgtatgta caccaaaatc tggaaaaaca atttgatcca gacatggtga
     5401 aggatccttg cggtcaaaga caatgcgtgc tggcactgat ttcttgagga caatcaactc
     5461 aggagtatag cctcccatga cttccactcg aatctcttgg tatccatttt tttgctgggc
     5521 tttttgtcca gatttttcag gctttttgaa aaaccaaaac aagataaacg cgataagggc
     5581 aatacaaata atggttacaa tactatttaa catgacgtct cctttacata caattacatc
     5641 ttacttctgt tacagcactt gatttcttct ctgaaatcac agcttccaag tcttccaagt
     5701 cagtctgagt aaattcacat tctacaatca agtcagccaa caaattccta atcctacggg
     5761 aacaaacctt gtctttgata tcttggacaa gtaaatcccg actttggtct agagttaaaa
     5821 gggctgaata aacaaaggac ttgccttctt ttttccgagt caaacactct ttctcaacca
     5881 gccgagacaa aagtgtctga accgttgact tggaccaatc aaaccgctct gccaaaaccc
     5941 taatcaaatc tgtactggtc tgctccccct gcatccaaat aatcttcatg acctgccatt
     6001 ctgcatctga aatctgcatt accatacctc caaaatctac atttgtcaat tacactcatc
     6061 agtatactct caaaatctac atttgtcaat tatagaaata atattttctt cgaaaaatag
     6121 aattttaatc atttgaaaaa cgatttgcag tcaaatatta ctatataaac aataaaaata
     6181 tgctatacta aagaaaaaag aaaacaacca ctaggggtgc gtaaagctga gattaacgac
     6241 tgttagatcc ctctgactca atctaggtaa tgctagctga tggaagtgga aatgataatg
     6301 gggactagca gtcttctatt gcctttctaa aacagactag cttgttctta agaatacaaa
     6361 cttcagttgg ttgggaggtt ttagatgact tatttacccg ttgctttgac cattgcaggg
     6421 actgacccta gtggtggtgc tggcattatg gcagatttaa agtcattcca agcgagagat
     6481 gcctatggaa tggctgttgt aaccagtctt gtcgctcaaa ataccagagg tgttcagcta
     6541 atcgaacacg tttctcctca aatgttgaaa gcccaattgg acagtgtctt ttctgatatt
     6601 ccacctcagg ctgtaaaaac tggaatgttg gctactactg aaatcatgga aatcatccaa
     6661 ccctatctta aaaaactgga ttgtccctat gtccttgatc ctgttatggt tgctacaagt
     6721 ggagatgcct tgattgactc aagtgctaga gactatctca aaacaaactt actacctcta
     6781 gcaactatta ttacgccaaa tcttcctgaa gcagaagaga ttgttggttt ttcaatccat
     6841 gaccccgaag acatgcagcg tgctggtcgc ctgattttaa aagaatttgg tcctcagtct
     6901 gtggttatca aaggcggaca tctcaaaggt ggtgctaaag atttcctctt taccaagaat
     6961 gaacaatttg tctgggaaag cccacgaatt caaacctgtc acacccatgg tactggatgt
     7021 acctttgctg cagtgattac tgctgaacta gccaagggca agagtcttta ccaggcagtt
     7081 gataaggcca aggcctttat cacaaaagct attcaagatg cccctcaact cggtcatggt
     7141 tctggtccag tcaaccatac aacttttaaa gattaagaaa aaaaaactct ctagttccca
     7201 ctttaaggga attagagagt ttttatactc ttcgaaaatc tcttcaaact acgtcagctt
     7261 ccatctgcaa cttcaaaaca ctgttttgag ctgacttcgt cagtcttatc taaaacctca
     7321 aggcagtact ttgagcaacc tgcgactagc tttctagttt actctttgat tttcattgag
     7381 tattaattag gaaagaatgt catgcaactt tgttaaaaag gcttgcgttt ttgcctcaat
     7441 atcttctgct tgcatcaaat cacgtacaac agctacacca gctatgccag cgcccataag
     7501 ctgatcaata ttctccgaag tcaagccacc aatagcaact attggaatgg caaccgtttg
     7561 gcaaattgtt ttcaaggttg aaatcagggt gatgggtgca ttttccttgg tggttgtcgg
     7621 aaaaatggct cctgtcccca agtaatctgc acctgatttc tccgcttcca gagctctttt
     7681 aaccgtttta gcggtgacac cgaggatttt ttcaggaccc aagacttgtc gggcaaccga
     7741 aactgggagt tcgtcatctc caatatgcag accagcagca tcaaccgcaa gacaaacatc
     7801 caaccgatca tcgattatca agggtacctg ataagcatct gttatttcct tgacttgttt
     7861 tgccagttga taatattgat tggttgtgag atttttttct cgcaattgga ctatggtaac
     7921 ccctgaacgg caggccgtct caacttttgc aagaaagctt tccacggaat cttgatagcg
     7981 attggttacc agatatagtc taagtgcttc tctattcata aacctctcct ttgatggtat
     8041 ctagccaatt ttcatctctt cttaggagcg aaagctgatt gagtacttgg taacgaaatt
     8101 cttccaatcc cattccttga acaactattt tctcagcagc gatattgaga taagagactg
     8161 ctaagcaaga agcttcaaaa ccagtctttc cttggctgag aaaaacggct gttaaggctc
     8221 caaccaaatc tcctgtccct gttatccagt ctaattctgc acagccattt cccagtacag
     8281 cgacctgatt tttcgaaacg acgaggtcct tgggacctgt gactaagaaa gacataccat
     8341 gataggtctg acaccagtct ttcaagactt gaagcaaatc ctccgtttct tgatctttag
     8401 cactcgcatc gaccccaacg ccgtggtgct ttaatccaac aagacttcga atttctgaca
     8461 tgtttccttt aaggaccgta ggtctatagt ctaaaaggtc tctgactaag ctcttacgaa
     8521 tggatgaagt cgttacgcca accgcatcta ctaccatcgg gagagaagat tggtttgcat
     8581 acaaagctgc catgcggatt gctttttcct tctcagctga caaatgcccc aaattgatga
     8641 agagagcctg actttgctta gtaaaatcaa gaacttcacg gggatcatct gccatgacag
     8701 gtttgcatcc cagagccaaa atcccatttg ccagcatctc acaagaaatc tcattggtca
     8761 tacagtgaat gagggaacta gagcctatag gaaaaggatt tgtcaatgcc tgcatcattc
     8821 tatcctttca gcaaagaaat atccttgcac ttttttaaag aattcctgct tgattaaaaa
     8881 tctaaatgca ataaaggaaa tcgctgtacc aatcaaggtt gctccgaaaa atcgaggagt
     8941 gtagataaac caactaagct tagcagccga tcctgtaaag agcaccataa caggatagga
     9001 aacaatagaa ccaataatac ctgttcccac aatttctccc aaggcagaaa agtaaaattt
     9061 tcgaccgtac ttataaaaga gacctgctag aagggctcca aaagtcgctc ctgtgagagc
     9121 taaaggcgga atcccttgag tcgtcatacg gataaaggct gtcactgtag ccatagccaa
     9181 ggcataaaca ggtcccatca tgattcccgc tagaatattg actacactgg acatcggtgc
     9241 cattccctca atccgaaaga taggtgtaag gactacatca agggcaatca tcatagataa
     9301 aatggtcaat ttgtgaactt gtagttggtg ctttctcatg tttctattct tctccttttt
     9361 ctaaagactg taaatcgctc ttccatgtct ggtgttggta agccatctcc caaaacttgg
     9421 cttccatatg aacactgatg tggaaggcat ctagcatttt ttgcttatct gtctcatcac
     9481 tttctcgata aagctgattg accagtgctc cctcctctct gatctgttgc tctaactcat
     9541 ccgtaatata agtttcaatc cattgttgat agagaggatt tggtgatggt ttaagattaa
     9601 gtgatttgcc tatatcatgg tataaccaag gacaaggaag caagcttgca aaagctatgg
     9661 ctaagttcgg ttctgcaaat tgcctataaa tatgagaaat gtaatgataa caggttggag
     9721 cgattggatg ttgctccatt tcctggtcgt tgatttccaa ttccttgaaa aattgttggc
     9781 gaataaataa ctcaccctcc actaaaccct gagcattttg tttcaagagt cttttcatct
     9841 cttggtttga agtcttatca gccaaaagat gatagatttc tgagaaagcc ttcagatagt
     9901 aggcatcctg aatcaggtaa tagcggaaaa tggcaggttc taaattcccc tcttgtaatt
     9961 gtaaaataaa gggatgatga aaggaagcct gccaagcttt cttggataat tccatcgcaa
    10021 tatctgtaaa ttccataata actcctttat aaaaatagac tggtttgaag caataaaaag
    10081 aaaagcaggt agattaattt tgttttttta ggaatataaa aagtccgata gctattcttc
    10141 aactgtgcat gttcgtcata tccgtgagca gatagagctc tcaggtaaag atggcgccac
    10201 ctaaagactg tcatcagaac cttactgtaa atcaagggcg accaaaaatg tagtttttga
    10261 ccacgtaata ggcaagcttc tttgagggac ttgatttctt gctgaatgag aggaaaagaa
    10321 ttgaatacca caatcaaggc ataggaccaa gagcgtgata gccccttttg agccaagtac
    10381 aagagaagct cttttagtga aatagaggaa acaaagacaa ggccgataca aactgtcaca
    10441 aaggccctcg ttccaagcat gactgcctgt gaagcatctc cgtgtaactg aactgcccag
    10501 tagttggcaa aagatggtaa aatggcaagt atgatcatcc aagctaacat tttaaatcga
    10561 cggtaataga gcataaagag aatacaaaat gcgactaccg aaagattcag agcaatcgaa
    10621 ggaatgaaag atgtttccaa ggataaaatc agcaagaaga gactgataat cggtgtctgg
    10681 gttgctactt tgaccatact atctcacctc cccttgggta ttgctactct gagatgtaag
    10741 tggtttggta atggtcactt ctttcacatg ccgaagaccc tgactagtca tctcaatcca
    10801 ataatcaacc acagaaatca aagggtctaa acgatgacta atgagcagaa aacttcttcc
    10861 ttgattcctc tcctccacaa tccacttgca aaaataatgg caggctctat catccaaacc
    10921 tgcaaaaggt tcatctagca agatcacgga agccttactg gtcaagatgg tcaagagctg
    10981 aagaattttt tgctgaccac cacttaattg atagggactc ttatcgactg cctgctccaa
    11041 atcaaaatct cgtaaagctt gaaaaatccg ctgatttctt tcagaatcag gtccatctaa
    11101 ttgaagctcc tctcgcagac tgactcgaat aaactgcttc tcagcttcct gaacaacacc
    11161 agtcagatca cgatacaaac tctttttctt tttcagaacc gaacccttcc aagtaatgct
    11221 ccccttatac ttttgaaatt gaagaataga gcgaaagaag gttgatttcc cgacaccatt
    11281 gtcacccagg atacaggaaa tcccttgata gaatgtgaaa tcagcaattg aaaagaggga
    11341 gcgatttcca aactcacaag tcgttctatc catatggaat agttccgggc tagaagcaac
    11401 ttcctttgaa gcaacctctg tcatctcata ggaagggatt tgaaacactt cccttagttt
    11461 tccgtctctt agctcaacca tatggtcgat ataggcttta tagtcagata aatcatggtc
    11521 gcacaaaata actgtcttcc catcaagagc caactctttt agaatctcca atatctcgat
    11581 tctgctcttg cggtcaatgg aagcgaaggg ctcatccaag agatataccc taggattcat
    11641 ggcaaagagg acagccagcg ctgctttttg cttttcccca cctgataggt gatgaatggg
    11701 acggtgtaag attgcctcgc aacgacattg ctggacaacc tctgctattt tagaatcaat
    11761 ttcctgaagg tgatagccga tattctccaa ggtgaaaatc agctcctcaa acaagttctc
    11821 catggtaaat tgatgattgg gattttgaaa gagaatgcca accttctgga cacgtgcgat
    11881 gatagaaagc tgactgacct cgctcccatc tatcaggact tgaccactat agggaggaga
    11941 actgacttgg gcaatgactt gaaaaaggct ggattttcct gaaccactgc tcccaactaa
    12001 caaggtaaag gcttgcgcat gaaaagtaaa atcaaacggc tcagggaaga ttggagactg
    12061 aatcgctcgt agttccagac ccatctatgc ttttcctcca gttgcaaact gatgatagag
    12121 tttgacaatg gcacgaacca agatggtaca gaagaaataa acagaaataa aacgtaccac
    12181 aagtaaggaa aggacaaacg gaagggaaaa ggcgtagtaa cctaacttaa tgtattcata
    12241 gacaaagcta acaagcgtaa tcccaatact attagcagtt agagagagcc aactttcata
    12301 gcgattctta gttacgataa aaccaaattc acttcccaaa ccttgaacca agccagacaa
    12361 aagagctcct agaccaaatt ggctaccata aaggacttca gcaagcgcag ctagcacttc
    12421 tccaatcgtt gcacttccga ctctcggaac aaagatggca gcaatgggcg cagccataca
    12481 ccagagaccg aagaggattt cattggcaaa ggcctgcaaa ccaagaggtg ttaagagtag
    12541 actgagaata ttatacacat atcctgaacc aacgaaaacc ccaccaaaaa agatagacaa
    12601 gaaagcaagc aagataacat cttttaactg ccattttttc aacataaaaa actccttttt
    12661 taaaagaaaa gtggggcact caagaagacc gacctaaata ctttgtatag cagattgatt
    12721 ttagaacagt acacaggaat gctaaaatat ttctagaaat taatttgaat tttctaattg
    12781 atttgttcgc atcttatttc aatctactat atcatcttca tccagtttcg taaaagaaaa
    12841 aactctaatt acagatacga attagagttc agcttacaag attagacagt tcttttcgac
    12901 atacgaaaaa aacatttcac atttcccttc gccagtctta actgtatcag gttcaatggg
    12961 tatcatctca gcctaaagca ccccaaatgc ctttattatt taattatgtg attattataa
    13021 cacacatttt atactagttc aagaaattga actggaaata cagccttgca ctcacaaaga
    13081 cagcagatct ttcttttgca aaaaacaaat gacctgtttg atgaattagc cattcaagct
    13141 gaatctagac atagcttttt aaaaaaggaa aatcctactt acttagaatc caaggataga
    13201 tatctattgt tcactcattt cccgaacagt tttttctata ttttttgcat acgatattgc
    13261 cgaaatgatt gaaacgccat ccatattggt ctttataatg tctttaatat gtttcgtctg
    13321 tatcccacca attgcaacta agggcatttg tggcaacagt tttctcatca atttaacacc
    13381 ttcataacct atagcaccac cagcatcatc ctttgactgg gtatcaaata caggcccaac
    13441 accaacataa tctacatatt caacttttga ttgttgaaat tcttcctcgt tttttataga
    13501 aagaccaatt attttatctg gcatcaattt tctaatttca tcaacaccaa tatcatcttg
    13561 acctacatgt acgccatcag cgtcaatttc cattgctaaa tctatatcgt cattaacgat
    13621 aaatggaaca ttgtattttt tacaaagttc tttaatttgg atagctagct caagtttttc
    13681 taagccttct aaagcaccct cacctttttc tcgaaattga aataaggtta taccaccttt
    13741 taaggcttcc tcaacgactg tatatagatt ttttccttgg caagtagtcg ttccacaaat
    13801 aaaatatagt tttagtaatt ctttatgaaa catcttactt cactcttttg aattccttta
    13861 catcttcatc tgtaatctcg tataaggcat ttataaattc aactttaaat gtcccaggaa
    13921 gatgtccatt tggacgtttt tctgccattt ctccagcgat attgtaaacc aacattgctg
    13981 tttctaatga tttcaattct tgaccttttt ctagtccgat aaagcttgct actacagctc
    14041 ctaataagca tcctgtccca atgactttcg gcatcatagc actaccatta tgaatcgtta
    14101 ccacttctcc attaacagca atggcatcca cttcacctgt tactactatt ggaatattga
    14161 acttctcatt tgctgctaga gcaatttcgt caatattatc tacgcccgca ctatctactc
    14221 ctttagatgc cacatctatt cctactaaag aggcaatctc gccagcattt cctctaatcg
    14281 ctgctagttt ataattgttg attagatcat ctgctacttt ttttctatat tctcctgctc
    14341 cacaggctac aggatctaaa actgctggga cattatattt ctccgcaatt ttcagagcag
    14401 cttggtataa tttccaattt tcatctgtca atgttcctat gtttattaat aaaccaccag
    14461 catactttaa caaatcctct aaatctgctg gaaactcact catggctggt gagacgctca
    14521 gtgctactaa tccatttgct gtgaaatttt ttactacatc attggtgata caaatgacca
    14581 atggtgcttt ttcttttaat aattttaaac ttgtcatatt gaaatccttc ctttacactt
    14641 tatacgatct actgatttcg atttatctct atctttcgtt aagaaatttt tttcatttac
    14701 gttgaatgat ttatactcaa tgaaaatcaa agagcaaact aggaggctaa ccgcaggttg
    14761 ctcaaaacac tgctttgagc ctgtagataa gactgacgaa gtcagctcaa aacactgttt
    14821 tgaggttgtg gatagaactg acgaagtcag taaccatacc tacggcaagg tgaaactgac
    14881 gtggtttgaa gagattttcg aagagtatta cctcatcaaa tttgtaaata tcatgagcct
    14941 tctctagaca tcgtaaccaa tatcaaaaaa agctaattct aaagcgactg cttgattcca
    15001 gcgttgctga agttctgtca aatcttctcg atttttaccg acacgattga gttcgtcaac
    15061 cagaaattga acccactctg caaagaaagg acctctgtgg agattgatcc attccgaatg
    15121 aatatagact tcaggtagag ccaaatcttt agaaccccag tctaaataga gaccttctgc
    15181 aatgaccagc ataaccaaaa gatgggcata gtctgatgaa gccactgccg aatacattag
    15241 atcctgaaag gcttttgtta cagggtgcaa agtcacttct agatagtcat tctctgctac
    15301 ttttaactct ttaaaagcct tttggaaata accatcttca tctgcttcaa gaaagcctag
    15361 ttgcttggca aaacgaagct tggattcaag tttatctgcg tgagctacgc aggcacccag
    15421 catggataag aaggcatcaa agaagtgata atcttgaatc agatagtcct ttaagacctt
    15481 attctcaatt gtccccgcaa aaagttcctt aacaaaacga tgattgattg cagcctgcca
    15541 atccttctga ctgcttttta ataattctcc aacagtcaaa cctggctgaa atgcatagtc
    15601 ttgtgtttcc atatttactt ctcctctctt tacttgttag taattaataa aacaccaaga
    15661 aatatcaagc aaaatcgtaa ttccacttga tccttttaaa gcacatcgag agcatttgca
    15721 gagagctaac taaacaagcc tatccagttt atataaacaa aaaactccaa ttacaatcaa
    15781 gaattagagt tgacttacaa gattagatcg ttcatttcgc catacgaaaa aacgtttcac
    15841 atttcccttc gccagtctta actgtatcag gttcaatggg tatcatctca gcttaaagca
    15901 ccccaaatgt ctctattatt taattactga accagtatag caaaaaatga aagccctagc
    15961 aagatatttg accgaaaaat atctttatat agtagattga aactagaata gtacacctct
    16021 acttctaaaa cattgttaga aatcgatttg actgtcctga ttgatttgtc ctattcttat
    16081 ttcattttac tatagttttc gatagcaatt tattcttcca atacacgaag aaaaacctcc
    16141 acattcagtg gaggcaatct gttttatcaa tacaatttta agtcacgagg gtcaactggg
    16201 aaggttgggt tgtatggatt gtgacggagc ttaaagtgtt tgacatcttc aatggtctga
    16261 gctccagaca attgcataac tgtcttcaat tccgcattca agtgttcaaa gacttgacgc
    16321 acaccgacac taccaccgag agccaagcca taaataacag ggcgaccaat agctaccaag
    16381 tctgctcctg aagccaaggc tttaaagacg tgttgaccac gacgaacacc agagtcaaag
    16441 acaatcggca cacgtctatc aactgcttct gccacttctt gaagcgagtc aaaggcagct
    16501 ggtccaccgt cgatttgacg accaccgtgg ttggttaccc agataccaga agctcctgca
    16561 gcaagcgaac gttcaacgtc ctcacggcat tgtggtccct tgacatacac aggaagacca
    16621 gagtattcag cgataaattc tacatcgcgt ggagacaagc gttgtttagc tgatttgtaa
    16681 acaaagtcca ttgatttacc agcaccttct ggcaggtatt cttcaacaat cggcatgcca
    16741 actgggaaga caaaaccatt acgcttatcc acttcacgat tcccccctac agtagcatct
    16801 gccgtcaaga caatcgcttt ataaccttca gccttcacac ggtccatgat gtggcggttg
    16861 ataccgtcat ccttactaaa gtaaaattga aaccaatgag gtgtcccttg aagggcttca
    16921 gaaatctctg gaaggtcaac agtagagtaa gaactggttg tataaagaga accaaactca
    16981 tgcacaccac gcgcagtcgc cacttccccc tgttcattcg ctaatttatg ggccgcaaca
    17041 ggcgccataa tgattggtga agatagtttt tcacctgcaa attcaatctc tgtacttgga
    17101 ttttcaacat cgcaaagtgt atgaggaacg atgagtttgt ggttaaaggc gcggatattc
    17161 tctcttaaag tgaaagtatc ttccgcccca ctagcgatat agccaaatgc tgctttagga
    17221 ataacttgtt gcgccattgg ctccaaatca taggtattga tgaagtctac atgaccttct
    17281 gcattgcttg ttttgtatga cataaaatgc cctccttgat taagtaagcg tttgcttttt
    17341 actatacaac tataataact cttttttcaa tcattttcaa gagttttgct taaaaaccat
    17401 cttatttttt catacaatat actagcccta ctttccttaa actctaaacc ttagtctata
    17461 ttaagtgaat cgttgagatt ttttgcttcc aggcatttga actacttttt tatttgctga
    17521 ttctatctac taatactata aaaaaacaag tgaataagac accagaacat cctctaatag
    17581 gacctatgga cttatatcag tcccatatat actgtttaag caagatacta tcctagttga
    17641 cgctaacttc ctatcccact tattaatttt ttatttatag tgaatctgaa caaatcaatt
    17701 ggggaatcca agtcaatttc tagtactttt tgaacagttt cagcgtacta tcgtaaaatg
    17761 aaataaaaca tgcacaaatt gattagggaa tttaaaccaa tttctaacaa tgtcttagaa
    17821 atcaaagtgt actatttcaa cttcaatata ctacacttca ttttctcctt aaattcagtc
    17881 tctttttgaa tcaaaaaatc ctctggtaag agccagagga taaaaattta tttcattgtt
    17941 gggaagagca atacatcacg gatagttgtt gtatcagtga ggagcatgca gagacggtcg
    18001 ataccgattc ccaaaccacc tgttggtggc ataccgtatt caagagcttc aatgtagtca
    18061 tagtcgattc ctgtcgcttc atcatcacca agttctttgg ctttagcttg ggcttcaaaa
    18121 cggctaagtt ggtcgattgg gtcgttgagc tcagtaaagg cattaccgta ctccttagtc
    18181 atgataaaga gctcgaaacg gtcagtaaag cgttggtctt caggattttt cttagcgagt
    18241 ggagatacag ctactggatg tccatagaca aaggttggtt ggattaaagt ttcttcaaca
    18301 aactcttcaa agaaggcatt gatgatgtga ccaacctcag tgtagtgttt ctcaactgga
    18361 actttcttct cagcagcgat agctttagct tcttccaaag tcatgtcttg ccagaaatcg
    18421 acaccagtaa tttctctgat agcatccacc atatgaacac gcttaaatgg ttcgttaatc
    18481 ttgatttcag taccttggta gttgactggg ccatcacctt tgactgattt agcagcatgt
    18541 tggataatgc cttccgtcaa gtccatgatg tcttggaagt ctgcataagc ttggtaaact
    18601 tcgatagaag tgaactcagg gttatgagta gcgtccattc cttcgttacg gaagatacgg
    18661 ccaatttcat agacacgttc cataccaccc acaataaggc gtttcaagtg aagctcagtc
    18721 gcgatacgaa gcaccatgtc aatgttttgg gcattgtggt gggtgataaa tggacgggca
    18781 gcagcaccac cggcttcatt atgaagaaca ggtgtttcca cttcaaggaa tcctttttgg
    18841 tcaaggtaac gacggatttc agagatgatt tttgaacgag tgacaaagcg ttcaaagctt
    18901 tcacggttag aaatcaagtc aaggtaacgt ttacggtaaa ttgtttcaac gtctgtcaaa
    18961 ccatggaatt tctcaggaag aggacgaaga gccttagaca agtgtgtgat gtgggttgcc
    19021 ttgatagaga gttctcccat atccgtgcgc atcacttcac cttcgacacc aaggaagtca
    19081 ccaagatctg cttttttgaa gatttcgtag ttttcttcac cgacagcatc cttacgaacg
    19141 tagatctgaa tctggccttc gcggtcttga aggtgggcaa aaccaacttt tcctttacca
    19201 cgtttggtta ccaagcgtcc tgcgatagta gctgtttcgt ttttatcgtg taattgttct
    19261 ttatcgaggt tggcatattt atcttttaat tcttgtgaat ttgcagtacg ttcaaaacgt
    19321 tttccgaaag gatcgattcc ttgttcgcgg agcgcagcca ttttttcacg gcgaacgatc
    19381 tgctggtcat ttagttcttc catatgttct gtagacatgg gatcctccta gttttactca
    19441 aaattgaata cgatgagtca ttttttgcga tacccccatt ttatcataaa taagcaagaa
    19501 attcacggat aatctttaaa aactaaaaag aacctgacgc taaaatcact gaaaagaagt
    19561 gaaagtatct tccgccccac tagcgatata gccaaatgct gctttagaaa taacttgttg
    19621 cgccattggc tccaaatcat aggtattgat gaaatctaca tgaccttctg catt
//
LOCUS       DAVMCG010000038        18896 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVMCG010000038 DAVMCG010000000
VERSION     DAVMCG010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18896
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.039"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            98..170
                     /locus_tag="VYP66_001601"
     tRNA            98..170
                     /locus_tag="VYP66_001601"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:131..133,aa:Thr,seq:tgt)
     gene            193..264
                     /locus_tag="VYP66_001602"
     tRNA            193..264
                     /locus_tag="VYP66_001602"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:225..227,aa:Gly,seq:gcc)
     gene            272..357
                     /locus_tag="VYP66_001603"
     tRNA            272..357
                     /locus_tag="VYP66_001603"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:306..308,aa:Leu,seq:taa)
     gene            367..440
                     /locus_tag="VYP66_001604"
     tRNA            367..440
                     /locus_tag="VYP66_001604"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:401..403,aa:Arg,seq:acg)
     gene            456..529
                     /locus_tag="VYP66_001605"
     tRNA            456..529
                     /locus_tag="VYP66_001605"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:490..492,aa:Pro,seq:tgg)
     gene            535..608
                     /locus_tag="VYP66_001606"
     tRNA            535..608
                     /locus_tag="VYP66_001606"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Met,seq:cat)
     gene            622..695
                     /locus_tag="VYP66_001607"
     tRNA            622..695
                     /locus_tag="VYP66_001607"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:656..658,aa:Ile,seq:cat)
     gene            706..795
                     /locus_tag="VYP66_001608"
     tRNA            706..795
                     /locus_tag="VYP66_001608"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:742..744,aa:Ser,seq:tga)
     gene            809..882
                     /locus_tag="VYP66_001609"
     tRNA            809..882
                     /locus_tag="VYP66_001609"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Met,seq:cat)
     gene            886..958
                     /locus_tag="VYP66_001610"
     tRNA            886..958
                     /locus_tag="VYP66_001610"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:919..921,aa:Phe,seq:gaa)
     gene            978..1048
                     /locus_tag="VYP66_001611"
     tRNA            978..1048
                     /locus_tag="VYP66_001611"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1010..1012,aa:Gly,seq:tcc)
     gene            1084..1157
                     /locus_tag="VYP66_001612"
     tRNA            1084..1157
                     /locus_tag="VYP66_001612"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1118..1120,aa:Ile,seq:gat)
     gene            1164..1251
                     /locus_tag="VYP66_001613"
     tRNA            1164..1251
                     /locus_tag="VYP66_001613"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1198..1200,aa:Ser,seq:gct)
     gene            complement(1377..2312)
                     /locus_tag="VYP66_001614"
     CDS             complement(1377..2312)
                     /locus_tag="VYP66_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1851133.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(2309..3169)
                     /locus_tag="VYP66_001615"
     CDS             complement(2309..3169)
                     /locus_tag="VYP66_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1851134.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            3277..5439
                     /locus_tag="VYP66_001616"
     CDS             3277..5439
                     /locus_tag="VYP66_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1851135.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALILCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRRHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKVTIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            5531..6790
                     /locus_tag="VYP66_001617"
     CDS             5531..6790
                     /locus_tag="VYP66_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1851136.1"
                     /translation="MEWYKKIGLLATTGLALFGLSACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLGKDIVAKGQIPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMINDLNVFFNPMKADVD"
     gene            6804..7670
                     /locus_tag="VYP66_001618"
     CDS             6804..7670
                     /locus_tag="VYP66_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1851137.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGELALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7684..8517
                     /locus_tag="VYP66_001619"
     CDS             7684..8517
                     /locus_tag="VYP66_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1851138.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHILSGMSNGAV
                     K"
     gene            8518..8598
                     /locus_tag="VYP66_001620"
                     /pseudo
     CDS             8518..8598
                     /locus_tag="VYP66_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8875..10317
                     /gene="gtfA"
                     /locus_tag="VYP66_001621"
     CDS             8875..10317
                     /gene="gtfA"
                     /locus_tag="VYP66_001621"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1851139.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            10455..11648
                     /locus_tag="VYP66_001622"
     CDS             10455..11648
                     /locus_tag="VYP66_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1851140.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            12334..14313
                     /locus_tag="VYP66_001623"
     CDS             12334..14313
                     /locus_tag="VYP66_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1851141.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            14380..15876
                     /locus_tag="VYP66_001624"
     CDS             14380..15876
                     /locus_tag="VYP66_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1851142.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15876..16802
                     /locus_tag="VYP66_001625"
     CDS             15876..16802
                     /locus_tag="VYP66_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1851143.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16811..17878
                     /locus_tag="VYP66_001626"
     CDS             16811..17878
                     /locus_tag="VYP66_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851144.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPHHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17889..18815
                     /locus_tag="VYP66_001627"
     CDS             17889..18815
                     /locus_tag="VYP66_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851145.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5461 a         3429 c         4064 g         5942 t
ORIGIN      
        1 ggtttggcgg aattggcaga cgcaccagat ttaggatctg gcgcttaacg gcgtgggggt
       61 tcaagtccct taacccgcat taagatataa caaatgagcc ggcttagctc agttggtaga
      121 gcatctgatt tgtaatcaga gggtcgcgtg ttcaagtcat gtagccggca tttttagata
      181 gaagaaaaca gtgcgaacgt agttcagtgg tagaacacca ccttgccaag gtgggggtcg
      241 cgggttcgaa tcccgtcgtt cgcttagaga ggccggggtg gcggaactgg cagacgcaca
      301 ggacttaaaa tcctgcgatt ggtaacgatc gtaccggttc gattccggtc ctcggcataa
      361 tatggagcac ccttagctca actggataga gtacctgact acgaatcagg cggttagagg
      421 ttcgactcct ctagggtgca tttttctatt taactcggga agtagctcag cttggtagag
      481 tacttggttt gggaccaagg tgtcgcaggt tcgaatcctg tcttcccgat tcatggcggt
      541 gtagctcagc tggctagagc gtccggttca tacccgggag gtcgggggtt cgatcccctt
      601 cgccgctata atgatcttgt cggaccttta gctcagctgg ttagagctct cggctcataa
      661 ccgagtggtc gtaggttcaa gtcctacaag gtccatttga atattggagg attacccaag
      721 tccggctgaa gggaacggtc ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga
      781 atcccacatc ctccttttat attattaacg cgggatggag cagctcggta gctcgtcggg
      841 ctcataaccc gaaggtcgta ggttcaaatc ctgctcccgc aataaggctc ggtagctcag
      901 ttggtagagc aatggattga agctccatgt gtcggcggtt cgattccgtc tcgcgccatt
      961 ttattgatag tatttatgcg ggtgtagttt agtggtaaaa ctacagcctt ccaagctgtt
     1021 gtcgcgagtt cgattctcgt cacccgcttt gaactttgtt caaattacca agttttttaa
     1081 cttgggcgcg tagctcaggt ggttagagcg cacgcctgat aagcgtgagg tcggtggttc
     1141 gagtccactc gtgcccatta attggagaat tactcaagag gctgaagagg acggtttgct
     1201 aaatcgttag gtcgggtaac tggcgcaagg gttcgaatcc cttattctcc gttttaatga
     1261 gagtctgtaa ctctcttttt tatttttaga gccaataaaa cttcagatcc gtaaaactta
     1321 attgaattac taatctgaag ttatttttat atcgtttata ttataattgt gttattttac
     1381 ttccaactat tgagagaaat ttcgccacta tttagccaga tttcttttcc gttatcacat
     1441 tgaactaaaa gttttccatt ttctgagatg tctttagcaa gtcccttgta gtctttttgc
     1501 tctagtgtga aagtgacttc ttttcctaga atgaatgact gttttttgta taggtataat
     1561 agctcttctg ctggtgtttc gaagaaagca cgccagattt ctatgatcaa ttcattcctt
     1621 gttataggag ctgtagcttt aaataagctg gcagcttttt cttttaattc ctgagggaag
     1681 tctttaatag tgaaattgat acctactcca ataatgatat ctgtgactaa gccagtttct
     1741 acagaggtca ttgcttcagt aaggattcct ccaattttat gattgtttag atagatatca
     1801 ttgacccatt ttatgtcgac atctattaaa gttaggttct taatggcttt gtagacagct
     1861 ccagctacaa gtagtgtgta ggatggtaat ttgtcatagg ggagatttgg tttaagatgg
     1921 agtgtcatat aaataccacc ttgtggtgag tagaaggaac gttgaaaacg gcctcggcct
     1981 gctgtttgat aggaagctag atagagggta tttgcttcat ggcctaaatc aattgcttct
     2041 tttgcatcta gttgtgttga ttttgtttcg ggtttaaagc tgactttaat tggaagattt
     2101 tcttctagaa tctctggaag aataaggtca ccattcatca gtttatatcc tctatttttg
     2161 atactatcaa tttcaatgcc ttcttgttct agtcgcttga tggctttcca aattgctgtt
     2221 cggcttaggg atagtttttc tgcgattttt tctccgctga tatagtcggt ttctttagat
     2281 aggatttggt agacagcttg gtaggatttc ataatgttgc ctttcttact agttggtatt
     2341 gagagtattc ttttcttgta tgacttggag tctgattaaa gtattgttta taagctttcg
     2401 aaaaatggag tggatctgaa aaacctaccg agtatgcaat taccttgatg gactcttggg
     2461 tattttcgag aagttgtcta gctcggtgca ttcgaacgta gagtaggtat tctttgggtg
     2521 ataaggtatt aaattctttg aatacgcttg ataagtagct tctgtgaacg gatagttctt
     2581 ttgctaaatc ttgaattgta agtgattgag gatagtggct atcaattaat cgtttgcatt
     2641 caagatagag ttggtgggtt gatgaaatat tctttttttt ctgattggga gcaatagttc
     2701 ccagatgaaa catcagttca tgaagttgtc ccatgatatg gagttgagct aattcacttg
     2761 attttgtaat ctgagcgaag cggacaatgt ctgagatgag ttttgcagta gtctgggtat
     2821 gacaagtttc agattggatg agataggatt gatcagaaat ttgggaaaga gcaaaataat
     2881 caggggcttt ccctccagtg attcctaacc agtagtaggc ccaaggttct ttactatctg
     2941 cttgataaaa ggttagttcc tctggtttta atagaaagaa atctccttct tttaaatcaa
     3001 caattttacc cttgtaatga aattttcctt gtcctttagt aatgtaatgt agaacgtatg
     3061 tatcacgaat ggctggacca aaagagtaat taggtgtgca ttcctcatat ccataaaagc
     3121 ttagggcaag gtcgattgtt ccagtctggt attctgaaaa aactaacatg tgctacctcc
     3181 tacctaacat tttaccatat tcttgagaca tttttctatt ttggaaagcg atttcaggtg
     3241 ataaaatata atcaataaag tgatgaggtg aagtaaatgg gagttaggat agagaataat
     3301 ctattttatg ttgagagtaa aaatctaagt ttgattattg aaaatcgaaa tggctactta
     3361 cttttgaaac atttaggaaa gactattaag aactataaag gttccaatag tgtttatgaa
     3421 cgagaccatg ccttttcagg aaatccaacg gctactaatc gaacctttag tttagatact
     3481 cagcgacaga tttttggaca acatggctta ggagatttta ggaaaccaac catacaggtt
     3541 cagcatagtg taactgaagt aacagacttt cgatttgtag aagcaaagat tttaaaaggt
     3601 cagaatggtc cacagggctt accttctcca catagcatgg acgatacaga gactcttgtc
     3661 ttaatgttag aagattctaa ggctcaactt agtctgactt tgtattatac tacttttaat
     3721 aatgatgcga ctattgctag ctacagtaaa ttagataata atagtaatca ggaagttgtc
     3781 atccataaag atttttcttt tatggctgat tttccagctg cagattacga aatagtaact
     3841 ctgcagggtg cttatgctcg tgaaaagact gttagacgtc aacaggtaga acaaggaatc
     3901 ttttcgatta gttcaaaccg aggtgcttct ggtcatgctc aaacaccagc tcttatacta
     3961 tgcgaacaag gagtcacaga ggatgctggg aatgtgtttg ctattcaact aatgtatagt
     4021 ggcaactttg aagcttttgt tcaaaaaaat caattgaatg aagttcgggt ggctattggc
     4081 attaatccag aaaacttttc ttggaagtta gcccctgagg aatactttga aacaccggta
     4141 gctttagtga ctcattcaga tcagggatta actggtatta gtcatgaaag tcagaatttt
     4201 gtactgaagc acattatgct aagtgaattt tctaaaaaag aacgtccaat tctaatcaat
     4261 aactgggaag ctacttactt tgactttcag agagaaaaac tgttagagtt agcagatgaa
     4321 gctaagaaag ttggcattga actttttgta ttagatgatg gttggtttgg caatcgtttt
     4381 gatgataatc gtgctttagg tgattgggtt gttaatgagg aaaaactggg tggaagtcta
     4441 gaaagtctga tttcagctat ccatgaaaga ggtttgcagt ttggactttg gttagaaccc
     4501 gaaatgattt ctgtagatag tgatttgtat cgtcgacatc ctgactgggc tattcaggtt
     4561 cctgactatg agcatactta ttctcggaat caattagtac ttaatcttgc caatcctcag
     4621 gtagtagaat acttgaaaag tgtcttagat caactcctat cttatcatga tattgattac
     4681 attaaatggg atatgaaccg caatatcact aagctaggga atggattaac ttatctagag
     4741 acacagatgc aatctcatca gtacatgctg gggctttacg aactcgtttc ttatctgaca
     4801 gagaagcaca gccatattct ctttgagtcc tgctctggtg gtggtggacg aaatgatctt
     4861 ggtatgatgc gctatttccc acaagtctgg gctagtgata atactgatgc cattgcacgt
     4921 ttaccaattc aatacggttc atcctatctc tatccaacca tttctatggg ggctcatgtg
     4981 tcagcagtac cgaatcatca gatgggacga atgacaccat tagaaacacg tggccttgta
     5041 gcaatgatgg gaaatttggg ctatgaactt gatttgacaa atttatcaga tgaagagaaa
     5101 gttacgattg ctaatcaggt gaacttgtat aaagaattac gaccagtagt tcagttagga
     5161 cagcagtata gactaattaa tcctgatact gcatccaatg aagcagctgt acaatttaat
     5221 tacggaaatc aaacgattgt aacctacgtt cgcgttttat ctgttgtaga gaccatggaa
     5281 acaactttaa aattaaaaga tttggatgaa gagggactat ataaattaca ggaaaatggc
     5341 gaagtttact caggtgcaga actaatgtat gcgggcttaa ctgttatctt atcccaagga
     5401 gattttttga gtagacagta tatttttaga aaactatgat atgtactgac cccaaaagtt
     5461 agatttattc tgtctaactt ttggggtgca gatcaataag ggtgtataaa tttataaagg
     5521 aggctttcta atggaatggt ataaaaaaat cggacttctt gcaactacag gtttagcttt
     5581 gtttgggctc agcgcttgct ccaactatgg taaatctgcg gatgacacag tgaccatcga
     5641 gtatttcaac cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc gtgattttga
     5701 gaaggaaaac cctaagatca aggtcaaagt cgtcaatgta ccaaatgctg gtgaagtatt
     5761 gaagacacgc gttctcgcag gagatgtgcc tgatgtggtc aatatttacc cacagtccat
     5821 cgaactgcaa gaatgggcaa aagcaggtgt ctttgaagat ttgagcaaca aagactacct
     5881 gaaacgcgtg aaaaatggct acgctgaaaa atatgctgta aacgaaaaag tttacaacgt
     5941 tccttttaca gctaatgctt atggaattta ctacaacaaa gataaattcg aagaactggg
     6001 cttgaaggtt cctgaaacct gggatgaatt tgaacagtta ggcaaagata tcgttgctaa
     6061 aggacaaata ccatttggaa ttgcaggtgc agatgcctgg acactcaatg gttacaatca
     6121 attagccttt gcgacagcaa caggtggagg aaaagaagca aatcaatacc ttcgttattc
     6181 tcaaccaaat gccattaaat tgtcggatcc gattatgaaa gatgacatca aggtcatgga
     6241 catccttcgc atcaatggct ctaagcaaaa gaactgggaa ggtgctggct ataccgatgt
     6301 tatcggagcc ttcgcacgtg gggatgtcct catgacacca aatgggtctt gggcgatcac
     6361 agcgattaat gaacaaaaac cgaactttaa gattgggacc ttcatgattc caggaaaaga
     6421 aaaaggacaa agcttaaccg ttggtgcggg agacttggca tggtctatct cagccaccac
     6481 caaacatcca aaagaagcca atgcctttgt ggaatatatg acccgtccag aagtcatgca
     6541 aaaatactac gatgtggacg gatctccaac agcgatcgaa ggggtcaaac aagcaggaga
     6601 agattcaccg cttgctggta tgaccgaata tgcctttacg gatcgtcact tggtctggtt
     6661 gcaacaatac tggaccagtg aagcagactt ccataccttg accatgaact atgtcttgac
     6721 cggtgataaa caaggcatga tcaatgattt gaatgtcttc tttaacccga tgaaagcgga
     6781 tgtggattag gagtagagag actatgaaaa aagtattaca aaaatattgg gcatgggctt
     6841 ttgtggtcat ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg tttcaaggag
     6901 ccttttacag ttttaccaac tggacaggat tgacttataa ctacaaattt gtcggcttaa
     6961 acaactttaa gctcctcttc atggatccaa aattcatgaa tgcgattggc tttaccgcaa
     7021 tcattacgat tgccatggtg gttggtgagc ttgcactcgg gatcttcatt gcgcgtgtct
     7081 tgaattctaa aatcaaaggc caaaccttct tccgtgcttg gttcttcttc ccagctgttt
     7141 tatctggttt gacagtggct ttgatcttca agcaagtctt caactacggt cttccagcga
     7201 ttgggaatgc ccttcatatt gaatttctcc aaaccagtct tttagggact aagtggggag
     7261 caatctttgc ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc atcatcatct
     7321 tcctagctgg tttgcaatct attccaactg agattacaga ggcagcaagg attgatggtg
     7381 cgactagcaa gcaagttttc tggaacattg aattgcctta cttgctacca agtgtctcta
     7441 tagtctttat cctagcccta aaaggtgggc tgactgcctt tgaccaagtc tttgccatga
     7501 ccggtggtgg tccaaacaat gccacaacct cacttgggct cttggtttat aactatgcct
     7561 ttaaaaacaa ccaattcggt tatgccaatg ccattgccgt aatcttgttc ttcttaattg
     7621 tagtgatttc gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa gaggagaagc
     7681 atgatgaaac aagatgaaag aaaagccctg attggcaaat acattctatt gattctagga
     7741 tcggttctga ttttagtgcc gctccttgct accctcttta gttccttcaa acccactaag
     7801 gatattgtag ataatttctt tggctttcca accaacttca catgggacaa ctttagccgt
     7861 ctcttagctg atgggattgg aggctattat tggaactctg tcgtcatcac tgtcttgtct
     7921 ttacttgcag taatgatctt tatccctatg gcagcctact ccatcgctcg caatatgagt
     7981 aaaagaaaag cctttaccat catgtatacc ctcttaatcc tcggaatctt cgtacctttc
     8041 caagtcatca tgattccgat tacggttatg atgagtaaac tcggtttggc taataccttt
     8101 ggtttgatct tgctctactt gacctatgcg attccacaga ccctctttct ctatgttggc
     8161 tatatcaaaa tctcgattcc agaaagtctg gatgaagcag cagagatcga tggggctaat
     8221 caatttacaa cctatttccg catcatcttc ccaatgatga aaccgatgca tgcgacaacc
     8281 atgatcatca atgccctttg gttctggaat gacttcatgt tgccactcct tgtcttgaac
     8341 cgggattcca aaatgtggac tctgcctttg ttccaataca actacgcagg ccaatatttc
     8401 aacgactacg gaccaagctt tgcctcttac gtggtcggca ttatcagtat caccattgtc
     8461 tatctcttct tccaacgcca tatcctttca ggaatgagca acggggcagt gaagtaatac
     8521 tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gttgctcaaa acactgtttt
     8581 gaggttgtgg atgaaactga cgaagtcagt aaccatacct acggtaaggc aacgctgacg
     8641 tggtttgaag agattttcga atagtataag aagagctcat ggaatctata gtctttgaca
     8701 cagaggaaga gttcagcttg ttgataattc tatgtagaaa acaagaaagt agtactttgt
     8761 ttatcacagt ctatattagt acgagtttga tgataaatag agatttaaaa tgaattttat
     8821 ttatgaagcc agatcatatg agacttggct tcaattagaa aaaggagagt aatgatgcca
     8881 attcaaaata aaaccatgtt gattacctat tctgatagcc ttggaaataa tcttaaagac
     8941 ttatatgata atttggaaga gcattttgga gatgctattg gaggagttca ccttttacca
     9001 tttttcccat caacaggtga tcgtggattt gcgccagttg actacgacga agtggactca
     9061 gcttttggtg attgggagga tgttaagcgt ttaggtgaga gatattatct tatgtttgat
     9121 tttatgatta atcatatttc tcgtcaatcc aagtattata aggactatca agaaaaacat
     9181 gaagccagtg aatttaaaga tctcttttta aactgggata agttttggcc agaaaaccgt
     9241 ccgacacagt ctgatgtaga tttaatttac aagcgtaagg atcgtgcacc aaagcaagag
     9301 attgtgtttg aagatggttc agtggaacat ttgtggaata cctttggtga ggagcagatt
     9361 gatcttgatg tgaccaaaga agtaactatg gaatttatcc gtaagaccat tcagcacttg
     9421 gcaagtaatg ggtgtgattt gattcgtcta gatgcctttg cttatgcagt gaagaaattg
     9481 gatactaatg atttctttgt ggaaccagat atttgggatt tattggacaa agttcgagat
     9541 atcgctgctg agtatgggac agagctttta cctgagattc atgaacacta ttcgattcag
     9601 tttaaaatag cagaccatga ttactatgtt tatgattttg ctcttccaat ggtgacactt
     9661 tatactcttt acagttccag aacagagcgt ttggctaagt ggttaaagat gagcccgatg
     9721 aagcaattta cgacgctaga tacccatgat gggattggag tagtagatgt caaggatatc
     9781 ctgaccgatg aggagattga ctatgcttca aatgaacttt ataaggttgg agccaatgtc
     9841 aaacgtaagt actctagtgc cgagtataac aacttagata tctaccaaat caattcaacc
     9901 tactattcag cgcttggaga tgatgatgtc aagtattttc tcgctcgtct aattcaagct
     9961 tttgccccag gtattcctca ggtttactat gtgggtctat tagcaggcaa gaatgacttg
    10021 aaattattag aagaaactaa agaaggtcga aatattaatc gtcattacta tagcaacgag
    10081 gaaatagcaa aagaagtgca acgacctgtt gtgaaggccc ttctcaatct attttctttc
    10141 cgtaaccgtt cagaagcctt tgatctagaa gggactactg agatagagac accaacagct
    10201 cacagcattg taatcaaacg tcaaaataaa gataagtccg taacagcagt agcagaaatt
    10261 gatttgcaaa atcagactta tcgggtaatt gagaatggag ttgaagtaac attttgaagc
    10321 cttgatatgg tggataaaat agggttttta ttttggaaaa cgtttccttt gttttcaaat
    10381 tgctaaaaaa gtggtacaat ataggatagc ttactattat ctgaatcagc tgatttggag
    10441 agaaaggatt cattttgaaa tcaataggct ttattgaaaa gctgaagggg ttgtctagta
    10501 aagagctgat tttattggga attatcctga gtatcttttt acccttttat ctttttgtag
    10561 ttgtactctg tttatatatt atcagtttga tttttacagg agacatgaaa agtattcttc
    10621 agaaaatggg ggagcatccg atgctgcttc tttttcttag ctatagtact gttatatcca
    10681 ttcttgcaca aaattggatg ggtcttgtgg cttcagtagg aatgtttcta tttactattt
    10741 tctttttgca ctatcagtcg attttatccc ataaattctt tcgattgatt ttgcagttcg
    10801 tcttgtttgg tagtgtcttg tcagctgctt ttgccagttt agaacatttc caaattgtga
    10861 agaaatttaa ctatgctttt ctttcaccca atatgcaggt gtggcatcag aaccgggcag
    10921 aagtgacctt ctttaatcct aattattatg gaattatttg ttgtttctgt attatgattg
    10981 ctttctatct gtttacaacg accaagttga attggttgaa agtattctgt gtgattgcag
    11041 gctttgttaa tctctttggt ttgaacttta ctcaaaatcg aactgccttt cctgctatta
    11101 tcgctggagc aattatctat ctctttacga ctattaaaaa ctggaaggcc ttttggctta
    11161 gtattggggt cttcgcgatt ggtttgagtt tcctcttttc tagtgatttg ggagttcgaa
    11221 tgggtacttt agactcttct atggaagaac gcatttctat ctgggatgct gggatggcct
    11281 tgtttaagca aaatcctttt tggggtgaag ggccattgac ctatatgcac tcttatcctc
    11341 ggatacatgc tccttatcat gaacatgccc acagtcttta tattgatacg attctgagtt
    11401 acggaattgt gggtaccatt ttattagttt tgtcttctgt tgctcctgtt cgcttgatga
    11461 tggatatgag tcaggagtcg gggaaacgtc cgattatcgg cctttatcta tctttcctta
    11521 cagtggttgc tgtgcacgga atttttgact tggctctctt ctggattcag tcaggcttta
    11581 ttttcttgct agttatgtgc agtattccat tggagcatcg aatgttggta tcggacatga
    11641 cggattaagt tttataagtt tgaaatcttc taccttgggt aggagatttt tttatacgat
    11701 gggcatgtcg tgcatctgag gtgtaagtcc tctgtaggga tccactaccg gtgaatacaa
    11761 tagcgctccc caagcctgac tatcgtgagg tagcggatta aaatggtctg gggatagatc
    11821 gttttaagtc tgacgcagga aataagaatt gtcagagaaa gcaatagtga aatcgtaggc
    11881 tatgaataga aacgtgatag cgaggagcat atagtggaca aggtagcgag aaattttaaa
    11941 gtataaaaga tagtcttaat ctatatgtgt aaatcacgaa agtaattgaa ttcggaataa
    12001 ggttggtgtg aaaagacata gtaaactgaa tcttgaatac tagaatgata cttctacaat
    12061 attgttataa tttaatttga attccaaaat cacattgttc cgtccgtatt tcattttact
    12121 gtatgtcttc ctaagctcca aaatttctgt gtcaaatttc ctattttcac tgtagtcttt
    12181 gacacttcga acgacaattt gaatcatata ttcaaaaaaa atgaaaaatt tgtgccaaca
    12241 agcctaaata ttctgaaaat ttgtttgatt tttaatggat aatgtgatat aatggttgtc
    12301 aatctataat tcacataaac agaggagtag aaaatgaaaa aaaatcgtgt atttgctaca
    12361 gcaggtcttg ttttattagc agcaggtgta cttgcagcat gcagttcttc aaaatcatct
    12421 gattcatcag cccctaaagc ttatggctat gtttatacag cagacccaga aaccttggac
    12481 tacctgattt caagtaaaaa tagtacaaca gtagtgactt caaatgggat tgatggttta
    12541 ttcactaacg ataattacgg taatcttgct cctgcagttg cagaggattg ggaagtctct
    12601 aaggatggtt tgacctacac ttataagatt cgtaaagggg ttaaatggtt tacctctgat
    12661 ggagaagaat atgcagaggt gacggctaaa gatttcgtga acggtttaaa acacgcagca
    12721 gataaaaaat cagaagctat gtatttagct gaaaattcgg ttaaaggctt ggcagattat
    12781 ctatcaggaa cttcaacaga tttttcaaca gttggtgtca aggcggttga tgattatacg
    12841 ttacaataca ctttgaacca gcctgaaccg ttctggaact ctaagttgac ctattctatt
    12901 ttctggcctc tgaatgaaga attcgaaaca tcaaaaggaa gcgattttgc taaaccaaca
    12961 gatccgacat ccttgcttta taatggtcca ttcttgttga aagggttgac tgcaaaatct
    13021 tctgtagagt ttgtaaaaaa tgagcaatat tgggataaag aaaatgtcca cctagatact
    13081 atcaatctag cttactatga tggatcagat caggagtcgc tagagcgtaa cttcactagt
    13141 ggagcttata gttatgcccg tctttaccct accagctcca actattctaa ggttgcagaa
    13201 gaatacaagg acaatatcta ttacacacaa tcaggctctg ggattgctgg tctgggtgtg
    13261 aatattgatc gccaaagtta caactatact tctaaaacta cagattcaga gaaagtagct
    13321 actaagaagg cattgcttaa caaagatttc cgtcaagcct tgaattttgc tcttgatcgc
    13381 tcagcttact cagctcaaat caatggtaaa gatggagcag ctttagcagt tcgtaattta
    13441 tttgtaaaac cagactttgt ttcagctggt gagaagacct ttggtgattt agtcgctgct
    13501 caacttcctg cttatggtga tgagtggaaa ggtgtgaatt tagctgatgg gcaggatggt
    13561 ttattcaatg ctgacaaggc caaggcagag tttgcgaaag ctaagaaagc tttagaagca
    13621 gacggcgttc agtttcctat tcatctggac gttccagtag accaagcatc aaaaaactat
    13681 atatctcgta ttcagtcctt taaacaatct gtagaaacag ttcttggtgt tgaaaatgtc
    13741 gttgttgata ttcaacaaat gacaagtgat gaattcctta atattactta ctatgctgcc
    13801 aatgcttcat ctgaggattg ggatgtatca ggaggagttt catgggggcc agactatcaa
    13861 gacccatcta cttacctgga tattttaaaa acaactagca gtgaaactac aaaaacatat
    13921 ttaggatttg ataatccaaa tagcccttca gtagttcaag ttggtttgaa agaatacgat
    13981 aaattagttg atgaagctgc caaagagaca agcgacttga atgtccgtta tgaaaaatat
    14041 gcagcggctc aagcatggtt gacagatagt tcactcttta ttcctgctat ggcttcttct
    14101 ggtgcagcac cagtgctttc acgaattgtt ccatttactg gagcttctgc gcaaacaggc
    14161 tctaaggggt cagatgttta cttcaaatat ttgaaattac aagataaagt ggtgactaag
    14221 gaagagtatg aaaaagctcg tgaaaaatgg ttgaaagaaa aagctgaatc aaatgagaaa
    14281 gctcaaaaag aattggcaag tcatgtgaag taaataattt ctaatagaac tttctctcca
    14341 tgaggagaag gttcttttgg gatttttaaa ggaaataata tgaaaaaata tatttttatg
    14401 cgtgttttgc ggtcattggt ttcgattttc ttagtaacga ctttgaccta cacgattatc
    14461 tataccttgg ttcctcgaaa attgattttc aagcaggatc ctaactataa taaaattgcg
    14521 acaacggctg ataaacgtga taactatgaa aatactgtgt ttgagcgtat gggctacatt
    14581 gagtattacg atactaaaga gttgcaagaa aaggcaagta gcatggattc ttctgtaaca
    14641 gtagaagcaa atgcgaccaa taaagctatt tatgaaaagt acatcaatca attaggtcat
    14701 ggttggactt tgggagaatt tactgaaagt ggtcaattct atgctactcg tgaaattcca
    14761 atttttgaac gtgtttttca cttctatgct aatttgattg acattgacca tacaaataaa
    14821 atccaagacc ctgaaaatcc agacttgaaa cgctaccttc gttttgaaaa tgatccagct
    14881 atcggatggt cattggtcgg ttcaggaact aaacataaat atctcttgta ctttaacagt
    14941 cagttcccat ttgttcatca aaactttgtg aacttgaatt taggtgactc ttacccaacc
    15001 tatgctaata caccagttct tcaggttatt actcaaggtc aaggacaaac caaaactgcc
    15061 caagttcagt tcccaacagg taagaaaacg tcttctgtaa atatttactc aagaacctac
    15121 aagtcaccta gtcaggctga ctctcgtgaa gtagctagct atgggaaaga tgatccttat
    15181 acagcgactg aaagtaatta ccaatatcca tctatgattg tcagctctgc tattactggt
    15241 ttgattggtt tggttcttgc ctatgctctt gccgtgccac ttggttcagc catggctcgt
    15301 ttcaagaaca cttggattga tagcctctca acagggactt tgaccttctt gcttgctctt
    15361 ccaacgattg ccttggttta catcgttcga ttgattggat catctattgc ccttccagat
    15421 tcattcccta tcttgggagc tggagattgg cgttcttacg ttttaccagc agtcatcctt
    15481 ggtttgttgg gtgctcctgt tacagccatt tggattcgtc gttacatgat tgacttgcaa
    15541 tctcaagact ttgttcgttt cgctcgtgca aaaggtttgt ctgaaaaaga aatttcaaac
    15601 aaacacatct ttaaaaatgc catggttccg ctggtttcag gaattcctgg tgccattatt
    15661 ggggttatcg gtggtgcaac ccttactgaa acagtcttcg ccttcccagg tatgggtaaa
    15721 atgttgattg actctgtaaa agcatctaat aactctatgg tcgttggtct tgtcttcatc
    15781 tttacatgta tttctatctt ctcacgtctt ttgggagata tttggatgac tattattgac
    15841 ccacgtatta aattgactga gaaaggaggc aaataatgtc tacaatcgat aaagaaaaat
    15901 ttcagtttgt aaaacgtgac gattttgcct ctgaaactat tgatgcgcca gcatattctt
    15961 actggaaatc agtgtttaaa caatttatga agaaaaaatc aactgtagtc atgttgggaa
    16021 tcttggtagc catcattttg ataagtttca tctacccaat gttttctaag tttgatttca
    16081 atgatgtcag caaggtaaac gactttagtg ttcgttatat caagccaaat gcggagcatt
    16141 ggttcggtac tgacagtaac ggtaaatcgc tctttgacgg tgtctggttc ggagctcgta
    16201 actccatcct catttctgtg attgcgacag tgattaactt ggttatcggt gtttttgtcg
    16261 gtggtatttg gggtatttca aaatcagttg accgtgtcat gatggaagtt tacaacgtca
    16321 tctcaaacat cccacctctt ttgattgtta ttgtcttgac ttactcaatc ggagctggat
    16381 tctggaatct gatttttgcc atgagcgtaa caacatggat tggtattgcc ttcatgatcc
    16441 gtgtgcaaat cttgcgctat cgtgacttgg aatacaactt ggcgtcacgt actttgggaa
    16501 caccaacctt gaagattgtt gccaaaaata tcatgcctca attggtatct gttattgtga
    16561 caaccatgac tcaaatgctt ccaagcttta tctcatacga agccttcttg tctttcttcg
    16621 gtcttggatt accgattaca gtgccaagtt tgggtcgttt gatttcggat tattcacaaa
    16681 acgtaacaac caatgcttac ttgttctgga ttccattgac aacccttgtc ttggtatcct
    16741 tgtccctttt cgtagttggt caaaacttag cggatgctag tgatccacgt acacatagat
    16801 aggagtagaa atgacaaaag aaaaaaatgt aattttgact gctcgcgata ttgtcgtgga
    16861 atttgacgtt cgtgacaaag tattgacagc cattcgcggc gtttcccttg aactagttga
    16921 aggagaagta ttagccttgg taggtgagtc aggatcaggt aaatctgttt tgacaaagac
    16981 cttcacaggt atgctcgaag aaaatggtcg tattgcccaa ggtagtattg actaccgtgg
    17041 tcaggacttg acagctttat cttctcacaa ggagtgggaa caaattcgtg gtgctaagat
    17101 tgcgactatc ttccaggacc caatgactag tttggacccc attaaaacaa ttggtagtca
    17161 gattacagaa gttattgtaa aacaccaagg aaaaacagct aaagaagcga aagaattggc
    17221 cattgactac atgaataagg ttggcattcc agacgcagat agacgtttta atgaataccc
    17281 attccaatat tctggaggaa tgcgtcaacg tatcgttatt gcgattgccc ttgcctgccg
    17341 acctgatgtc ttgatctgtg atgagccaac aactgccttg gatgtaacta ttcaagctca
    17401 gattattgat ttgctaaaat ctttacaaaa cgagtatcat ttcacaacaa tctttattac
    17461 ccacgacctt ggtgtggtgg caagtattgc ggataaggta gcggttatgt atgcaggaga
    17521 aatcgttgag tatggaacgg ttgaggaagt cttctatgac cctcaccatc catatacatg
    17581 gagtctcttg tctagcttgc ctcagcttgc tgatgataaa ggggatcttt actcaatccc
    17641 aggaacacct ccgtcacttt atactgacct gaaaggggat gcttttgcct tgcgttctga
    17701 ctacgcaatg cagattgact tcgaacaaaa agctcctcaa ttctcagtat cagagacaca
    17761 ttgggctaaa acttggcttc ttcatgagga tgctccaaaa gtagaaaaac cagctgtgat
    17821 tgcaaatctc catgataaga tccgtgaaaa aatgggattt gcccatctgg ctgactagga
    17881 ggaaggaaat gtctgaaaaa ttagtagaaa tcaaagattt agaaatttcc ttcggtgaag
    17941 gaagtaagaa gtttgtcgcg gttaaaaatg ctaacttctt tatcaacaag ggagaaactt
    18001 tctcgcttgt aggtgagtcc ggtagtggga aaacaactat tggtcgtgct atcatcggtc
    18061 taaatgatac aagtaatgga gatatcattt ttgatggtca aaagattaat ggtaagaaat
    18121 cgcgtgaaca agctgcggaa ttgattcgtc gaatccagat gattttccaa gaccctgccg
    18181 caagtttgaa tgaacgtgcg actgttgatt atattatttc tgaaggtctt tacaatcacc
    18241 gtttatttaa ggatgaagaa gaacgtaaag agaaagttca aaatattatc cgtgaagtag
    18301 gtcttcttgc tgagcacttg actcgttacc ctcatgaatt ctcaggcggt caacgtcaac
    18361 gtatcggtat tgcccgtgcc ttggtcatgc aaccagactt tgttattgca gatgagccaa
    18421 tttcagcctt ggacgtttct gtacgtgccc aagtcttgaa cttgctcaaa aaattccaaa
    18481 aagagctcgg cctgacctat ctcttcatcg cccatgactt gtcggttgtt cgctttattt
    18541 cagatcgtat cgcagttatt tacaagggtg ttattgtaga ggttgcagaa acagaagaat
    18601 tgtttaacaa tccaattcac ccatatactc aagccttgct ttcagcggta ccaatcccag
    18661 atccaatctt ggaacgtaag aaggtcttga aggtttacga cccaagtcaa cacgactatg
    18721 agactgataa gccgtctatg gtagaaatcc gtccaggtca ctatgtttgg gcgaaccaaa
    18781 ccgaattggc acgttatcaa aaaggactaa actagtaatg gttttataat ttccatgtca
    18841 atttttatgg aaattaggct ctttgtcaac tgtagtgggt tgaagtcagc taagct
//
LOCUS       DAVMCG010000039        18806 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVMCG010000039 DAVMCG010000000
VERSION     DAVMCG010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.040"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(293..1099)
                     /gene="yidA"
                     /locus_tag="VYP66_001628"
     CDS             complement(293..1099)
                     /gene="yidA"
                     /locus_tag="VYP66_001628"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1851146.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(1112..2416)
                     /locus_tag="VYP66_001629"
     CDS             complement(1112..2416)
                     /locus_tag="VYP66_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1851147.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2488..2865
                     /locus_tag="VYP66_001630"
     CDS             2488..2865
                     /locus_tag="VYP66_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1851148.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTNRYQVDGQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            2956..3288
                     /locus_tag="VYP66_001631"
     CDS             2956..3288
                     /locus_tag="VYP66_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1851149.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            3300..4871
                     /gene="ffh"
                     /locus_tag="VYP66_001632"
     CDS             3300..4871
                     /gene="ffh"
                     /locus_tag="VYP66_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1851150.1"
                     /translation="MAFESLTERLQNVFKSLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(5066..6349)
                     /locus_tag="VYP66_001633"
     CDS             complement(5066..6349)
                     /locus_tag="VYP66_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1851151.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6603..7316)
                     /gene="rsmG"
                     /locus_tag="VYP66_001634"
     CDS             complement(6603..7316)
                     /gene="rsmG"
                     /locus_tag="VYP66_001634"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1851152.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7410..7970
                     /locus_tag="VYP66_001635"
     CDS             7410..7970
                     /locus_tag="VYP66_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1851153.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7972..8871
                     /gene="htpX"
                     /locus_tag="VYP66_001636"
     CDS             7972..8871
                     /gene="htpX"
                     /locus_tag="VYP66_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1851154.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKHM"
     gene            complement(9020..10579)
                     /locus_tag="VYP66_001637"
     CDS             complement(9020..10579)
                     /locus_tag="VYP66_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1851155.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQSVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLQRLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10818..11134)
                     /locus_tag="VYP66_001638"
                     /pseudo
     CDS             complement(10818..11134)
                     /locus_tag="VYP66_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
     gene            11304..11846
                     /locus_tag="VYP66_001639"
     CDS             11304..11846
                     /locus_tag="VYP66_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1851156.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11846..12475
                     /gene="nth"
                     /locus_tag="VYP66_001640"
     CDS             11846..12475
                     /gene="nth"
                     /locus_tag="VYP66_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1851157.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12686..13207
                     /gene="pyrR"
                     /locus_tag="VYP66_001641"
     CDS             12686..13207
                     /gene="pyrR"
                     /locus_tag="VYP66_001641"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1851158.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13226..14149
                     /locus_tag="VYP66_001642"
     CDS             13226..14149
                     /locus_tag="VYP66_001642"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1851159.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14199..15278
                     /gene="carA"
                     /locus_tag="VYP66_001643"
     CDS             14199..15278
                     /gene="carA"
                     /locus_tag="VYP66_001643"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1851160.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15591..18767
                     /gene="carB"
                     /locus_tag="VYP66_001644"
     CDS             15591..18767
                     /gene="carB"
                     /locus_tag="VYP66_001644"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1851161.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         5470 a         3617 c         4222 g         5497 t
ORIGIN      
        1 tatttttagt gaagtatcct aatttgtata attgattgtg tgtagattca gggtcaattt
       61 gaagagagta tttaaaatat cttgggaaat tataatttct ccctgttttt tgagtccaat
      121 ctatgagtat gagttgccca ggagtaaggc cacattctaa atcgtttagg taaaaattgt
      181 tacaatcaga atttgtgtct ctattatgat tattttgttt taaattaaat agtttgctaa
      241 aaaaattcat tggattttat tgctaatcaa ttcttattga aaaatgatac ttttacagta
      301 cccatgttcg gatggcgtgg gcaacgccgg attcgtcatt tgttttagtg atgtatttgg
      361 cgattttttt gatttctgga tttccatttt ccatgacaac ggggtttcca acgacttcca
      421 gcatggcacg gtcattttct tcgtcaccga ttgccatggt ttcatctttg gtcaatccga
      481 gtttttcagc caagtgagta atagctgaac ccttgtctac attcttttta aggagttcga
      541 ggtagaaagg agcagatttg ttgatagagt agtgctcgta aaattcggct ggtatttttt
      601 caatcgcagc atcgagaatt tctggttcat cgatgaacat acacttgaca atttccttgc
      661 cagccatttc ttcaggggta cggtagaaga taggcatgct gacgagggtt gattcgtgta
      721 cagtgtattt tccgatattg cgatttgcag tatagatacc gtccttggta atggcatgca
      781 tgtggacacc gagcttgcga ctgaggaatt ccatatccag ataatcctca taggtcaagg
      841 attcgctgat aatctcatgg ccagtagcag tttcttggac aagggcacca ttgaaggtca
      901 ccacatagtc accttggtct ctcaactgca agtcgtccag aagtttggca acacctgcga
      961 tggggcggcc agttgcaatc acgactttga caccagcttc tttggcatct tggatggcag
     1021 aaaagacttc aggagtgatt tccttttggc tgttgactag ggttccgtca atatcgacgg
     1081 cgattagttt aatactcata aatttcctct tttagttttt atttggggta aaatgatcgt
     1141 tctcaatcaa gtgtaaaaat tgctgggtga tgcttgcgaa gatgctgttt tggtctaaca
     1201 tttctttcgg gaaataaaag cgattatctc cgtggcgact tccagcaagg gattggacga
     1261 taggggacag gctagagagt tctgccagtt ctccattttt ttgtaaaatc tcaatctgtg
     1321 tccttggatt ttcagattcg ggacggtaaa tatcataagg gaggtcaaag ttcttatgaa
     1381 tggcagtata gtagtcggga tcaaagccga tgtcctcaac caattttctc atgctagcga
     1441 gttggtcttg gtcttcttgt gaaaaggtaa tggatttaaa gaccttgcgg ttgacaaagc
     1501 gatgcgataa atctgcaaga atcttgtcag gactggtcat ccaaagctgg aagtaggtat
     1561 tcatcacgcc atcatccaga gccagatagt cagtcaaggt cacatttttt tcgaagaaag
     1621 gcaggaggtg tggagaagtt cgggcaaaga aatccttgtc ctcaggatag agttccttgg
     1681 cgcgtttgag aagattctgt aggagaactt ccatggcgcg tgttgcgggg tggaaataaa
     1741 cctgcatgta catctggtag cgactgagga cgtagtcttc gatggcgtgc atgccattgc
     1801 gctgaaaggc gataccattt tcgataggac gaatgactcg gaggattcga gtcaggtcaa
     1861 attccccata ggatgctcct gtaaaatagg agtcgcgcaa gagatagtcc atgcgatctg
     1921 cgtcaatctg actagaaatg agctgcacga cctgcttatt aggataggta tggtcaatga
     1981 cactggccac cttttctggg aaatcaggtg ccacttgtag caggacttgg tgaatctctg
     2041 tctcaggatt ttgaataatc tcctgagtaa tggcttcatg gtctgtatca aagagatttt
     2101 caaaagtatg ggagtaggca ccatgcccaa ggtcgtgtag gagagcagca gtcatggtca
     2161 agagagactc ggcaggattc cattcctcag gatatttttc ttcgaaaatc tctgtgatgc
     2221 gtcgtgcaat ttcatagact cctagacagt gagagaagcg actgtgttct ccaccgtgga
     2281 aggtataact ggaagttccc agttgtttga tccggcgcaa acgctgaaat tcttttgtat
     2341 taatcaagtc atagatgatt tgattattga catggatgta gttgtgaaca gggtcacgga
     2401 atactttttc gttcatatga ccattatagc aaaatcctgc tctttttggt aaaatagtag
     2461 gacaagagac aagaaagagg gcctgatgtg aagattcgga tgcgaaatac aattcagttt
     2521 gatgagcagt tggaagtaat tgaccagctt tatgatgtgg aagtgcatga aaaaggagat
     2581 tatagctacc tgcttttcta taatgaggaa aaggaaaaag tagtgattaa atttcatggt
     2641 caagaacttg tgatgagtcg attttccaat cccaagacca ttatgcgctt tctaaaggat
     2701 agtgatagtt tagcctatat tcccacacct atgggtatgc aggagtttat tatccaaacg
     2761 aatcgttatc aagtggatgg gcaaaagatt gaactagatt atcaactaca aaatcaagag
     2821 ggacatccct ttgccagcta tcaattggaa attacttggg gctaggctta tgtctttttc
     2881 aaatttagct atctatcttc ttggatcggc ttcctagtgt ggtagattag gctaattttt
     2941 ggtataataa aagttatgga aatcgaaaaa accaatcgta tgaatgcgct ctttgaattt
     3001 tatgcggcgc ttttgacaga taagcaaatg aattatatcg agctctacta cgctgatgat
     3061 tacagccttg ctgaaattgc cgaggagttc ggtgtcagtc gtcaggctgt ctatgacaat
     3121 atcaagcgaa cagaaaagat tctggaagat tatgagatga aattgcacat gtactcggac
     3181 tatattgtcc gcagtcagat ttttgatcag attttggagc gctatcccaa ggataacttt
     3241 ctgcaggagc agatagaaat tttaacaagc attgataata gagaataaga ggaagaaaaa
     3301 tggcatttga aagtttaaca gaacgtttgc agaacgtctt taaaagtcta cgtaaaaaag
     3361 gaaaaatctc tgaatctgat gtccaagagg caaccaaaga aattcgcttg gccttgctcg
     3421 aggccgacgt tgccttgcct gttgtaaagg actttatcaa gaaagttcgt gagcgtgcag
     3481 tcgggcatga ggtcattgat acacttaatc ctgcgcaaca gattattaaa atcgttgatg
     3541 aggaactgac agctgtttta ggttctgata cggcagaaat tatcaagtca cctaagattc
     3601 ctacaatcat catgatggtt ggtttgcagg gagctggtaa aacaactttt gcaggtaagc
     3661 tggctaacaa actcaagaag gaagaaaatg cccgtccttt gatgattgcg gcggatattt
     3721 accgtcctgc tgccattgat cagctgaaga cactgggaca acagattgat gtgccggttt
     3781 tcgctcttgg gacagaggtt ccagctgttg agattgtacg tcaaggtttg gagcaagctc
     3841 aaactaatca taacgactat gtcttgattg atactgcggg tcgtttgcag attgatgagc
     3901 tcctcatgaa tgagcttcgt gatgtgaaag cattggctca accaaatgaa atcttgcttg
     3961 tcgttgatgc tatgattggt caggaagcag ccaatgttgc gcgtgagttt aatgctcagt
     4021 tggaagtgac tggggtcatc cttaccaaga ttgatggcga tactcgtggt ggtgctgctc
     4081 tgtctgttcg tcacattact ggaaaaccaa tcaagttcac tggtacaggt gaaaagatta
     4141 cggacattga aaccttccac ccagaccgca tgtctagccg tatccttggc atgggggata
     4201 tgctcacttt gattgagaaa gcttctcagg aatacgatga acaaaaagcc cttgaaatgg
     4261 ctgagaagat gcgcgaaaac acctttgatt ttaatgattt catcgatcaa ttagatcagg
     4321 tgcaaaatat ggggccgatg gaagacttgc tcaagatgat tccaggtatg gccaacaatc
     4381 cagcacttca aaacatgaag gtggatgaac gccagattgc tcgtaaacgt gcgattgtgt
     4441 cttcgatgac acctgaagaa cgtgaaaatc cagatttgtt aaatccaagc cgtcgccgtc
     4501 gtattgctgc tggttctgga aatacattcg tcgaagtcaa taaattcatc aaggacttta
     4561 accaggctaa acagctcatg cagggtgtta tgtctgggga tatgaataaa atgatgaagc
     4621 aaatggggat taatccaaat aaccttccta aaaatatgcc aaatatggga ggaatggata
     4681 tgtctgccct tgaaggaatg atgggacaag gcggtatgcc tgacttatca gctctcggag
     4741 gagcaggaat gccagatatg agccagatgt ttggtggcgg tttgaaaggt aaaattggtg
     4801 aatttgccat gaaacagtcc atgaaacgta tggctaacaa aatgaagaaa gcgaagaaga
     4861 aacgcaagta agacaagaga ttgatgcaaa tctcatttga tgagaaaata aagtaaaaat
     4921 ttctatgata aaacgtacag tatcaaggtt ttagaatatc tgatattata cgttttttga
     4981 ttttaataat tttgttaaga cacttttatt atagtatacg aaaaatccac tcagctgtct
     5041 gagtggatta ggtgtattta gactcttagt ctttattttc gtatggcaag atcaagttca
     5101 agatgattcc tgtcatggct gaaagggcag tacctgaaag tgtaactgga ccaagtttaa
     5161 ggatagctcc tccaagtcca agaaccaaca tagcacttgc gatgatgagg tttcgcattt
     5221 gagcgaaatc aacacgttct ttaatcaaga ctttcaaacc attgctggcg ataaccccat
     5281 agagaaggat tgacatacca ccaagtacag cgtttggaat agttgaaatc aaggcagtga
     5341 atttaccaag gaagctgagg gcaatcgcga tgaaggcagc gttacggata actgagacag
     5401 aagcgatacg agtcataccg ataacccctg tattttctcc gtaagttgta ttggctggtc
     5461 caccaaggaa ggcagaaaca gaagttgcga taccgtcacc aataagagta cggtgaagac
     5521 ctggttcttt taagaattga cggccacaga tttgacccaa aacagtatgg tctccgatat
     5581 gttcagaaat tgttacgata gcgattggca agatagcgat ggcttctgga ccaaagtaaa
     5641 gattgtactc tttaaaggca ccacctgtgc taaatggcaa gtagaaacca ggaatttcaa
     5701 accagttagc ttctaggaca ggcgtaaagt caaccaaacc aagagttagc gcgaagaggt
     5761 aaccaccgat aatggcaaag aggaatggaa tgattcgtag gaagcctttt ccttttgtat
     5821 tgataaaggc agcaattagg aaagtaacaa cggctaccag agcatttttc caatttccgt
     5881 ctgctacaag acctgcattg gtaacagctg aacctgcaag tccaagaccg ataacgatga
     5941 tcataggacc gataatgatt ggtggcaaga gtttatcaat ccattttgtt cctacaaatc
     6001 ggatgctggt agcaacaagg acatagacca aaccagtcaa gataacccct gtttgagcag
     6061 cagatacatc cccccccatt tctttcatag ccagtgacat agctgtgata aaggcgaatg
     6121 aagaacctag ataaactgga actttaaaac cagtagcaat catgtagatg agtgttccaa
     6181 cacctgaagc aaaaagggca acagatacag gcattcccaa aatcaatggt accaagatgg
     6241 tcgcaccaaa catggcgaaa acgtgttgga aactaaggag aattcctttt ccagccgaag
     6301 gacgttggtc aacgtctagt aacaaatcaa cagttgattc ttgtttcata taaacctcac
     6361 ttttgggcat caaaaaagag cccattattt tacagcaata ggccctcaga gtaagacttc
     6421 tttaaaattt agattttaaa gagttttaaa tatttctgcg tcttcgtcac ctcacgggat
     6481 gacattaaaa acctttgctt aggatagtat agcagaaaaa aatgattttg taaatcattt
     6541 tttcccgagc ctagaaataa aagagcgagg ctgattttgt aaacatttgt ttactaaaaa
     6601 atttaaagtg ggcgtttatt tggcatacca gccttacgtg gatatttatt tggtgtttct
     6661 tttttctttt ctaccactgt gatatagcgc ggatctctat tcggtagggc gtagctgaga
     6721 ttgtcttcga ccttactaaa aaggagattg agggcattct tagcttctaa taattcctca
     6781 ggcgcattgc tagccttgag tgctaatagt ttgccaccaa ccttaaggta gggaatagtc
     6841 aattcagata ggacctgcat acgggcaacc gcacgagctg ttacaaaatc atattgagca
     6901 cggaagttct tgtcttgggc aaaatcttcg gcacgtccgt ggtagaaatg aactccgttc
     6961 aaatccagtt cttgagccaa gagttgtagg aagttgatgc gcttattgag tgaatcaata
     7021 atggtcacat ctaactccgg atagagaatt ttcattggta gactaggaaa tcctgcccca
     7081 gccccgatat caagaagttt gatagtttca ttgggaatca aaccttgaag aatgggtgca
     7141 atcgaatcgt aaaaatgttt gagataaact tcttccttgt ccgtaatcgc cgtcaaatta
     7201 atcttctcat tccactcgac caagagctca aaataacgtt caaattgttc tttttgctgg
     7261 tccgaaagtg gaagattctg ctcggcaagc aagttgtaaa atgtttttgg tttcatagtt
     7321 atttccttct ttagtatcat cttattttac cacaatcata gaaaatttga tatactggta
     7381 ctaatctaaa agcagaaagg acttatatta tgacttggat tattcttgga gttttagctc
     7441 ttgttgttat ttttgtgatt gttagctata acggtttggt taaaaatcgt atgcaaacca
     7501 aggaggcttg gagtcagatt gatgttcagt tgaaacgtcg aaatgacctc ttgccaaact
     7561 tgattgagac tgtaaaaggt tatgccaaat atgaaggttc tacccttgaa aaggtggcag
     7621 aactacgtaa ccaagtggcg gcagcgactt caccagcaga agctatgaaa gccagtgatg
     7681 ccctcactcg tcaggtttca ggtatttttg cagttgcaga aagctatcca gatttgaaag
     7741 ctagtgctaa ctttgttaaa ttgcaagagg agttgacaaa cacagaaaat aaaatttctt
     7801 actctcgtca actctataac agtgttgtca gcaactacaa tgtaaaatta gaaactttcc
     7861 cgagcaatat tatcgctgga atgtttggat ttaaagcggc agatttcctt caaacacctg
     7921 aagaggaaaa gtcggttcct aaagttgatt ttagcggttt aggtgactaa gatgttgttt
     7981 gatcaaattg caagcaataa acgaaaaacc tggattttgt tgctggtatt tttcctactc
     8041 ttagctcttg ttggttatgc ggttggttat ctctttataa gatctggact tggtggtttg
     8101 gttatcgcac tgattatcgg ctttatctac gctttgtcta tgatttttca atcgacagag
     8161 attgtcatgt ccatgaatgg agcgcgtgag gtggatgagc aaacggcacc agacctctac
     8221 catgtagtgg aagatatggc tctggtcgct cagattccta tgccccgtgt tttcatcatt
     8281 gatgatccag ccttaaatgc ctttgcgaca ggttctaatc ctcaaaatgc ggctgttgct
     8341 gcgacttcag gtctactagc tatcatgaat cgtgaagaac tagaagctgt tatgggacat
     8401 gaagtcagtc atattcgtaa ttatgatatc cgtatttcga ctattgcagt tgcccttgct
     8461 agtgctatca ccatgctttc tagtatggca ggtcgtatga tgtggtgggg tggagcaggt
     8521 cgcagacgaa gtgatgatga ccgagatgga aatggtcttg aaatcattat gctagtggtt
     8581 tccctactag ctattgtact ggcacctctc gctgcaacct tggttcagct cgctatttct
     8641 cgtcagaggg aatttctggc agatgcatct agtgtcgagc tgactcgcaa tccccaggga
     8701 atgattaatg ccctagataa gttggacaat agcaaaccta tgagtcgcca cgtcgatgat
     8761 gctagcagtg ccctttatat caatgatccc aagaaaggtg gggggttcca aaaactcttt
     8821 tatacccacc cacctatctc agaacggatt gaacgtttaa aacatatgta aaatgaaggc
     8881 tggaaaaaag tctttaaaat ctgaaaaacg cataatatca ggtgtgaaaa cttgatatta
     8941 tgcgttttac tatgggaaga tttacttctt tttctcctaa aattgtgttt ttgccccacc
     9001 tatctgctat gttgcaaatt tataaatctt ctaaattaac tagcttcaaa ccgtgttctg
     9061 tcatgcgata gatgatcgag cagacttctt ttaagaaacg acggtcatgc gaaacagtga
     9121 tgagaccgcc aggataagtg gcaaagagtt ttctgatttg gggttgagaa gtgggagaaa
     9181 agtttcgtgt gggttcatcc agcaggagaa agtttggttt gcgcaggact aaatccaaaa
     9241 gcaggagttt tccctgttgt ccgccagata aggagcgaat ttgatgctgc atttctggat
     9301 aactgaaatt gagactagct aggtgagatt ggattttctg tagttcctct ttttccccag
     9361 ttttactgag ataggctatt ggggataaat ccaattgcag ttttttgtgg taatcttgtg
     9421 gcataaaacc aagtgaaatc tctcttttat cattcagaag tctctgtaac ttggctaaca
     9481 gagttgattt cccaacacca tttggcccga taataccgat tttttcttgg ccacggacag
     9541 ttagttgtag tttttgaacc aaaactcggt cgtcaatgga caaattttct ttttccagtt
     9601 ggactaagac tttagaagct ggtaatggtt ggatgtctga aaagaaaagt tggatttgtt
     9661 cctcttcaag tggcttttga gtcatggact gagctgcctt ttcgtagcgt ttttcttgtg
     9721 agaggacagt tttcatcttt ttagccaata ggcgaccggc agtactatct ttggtagctc
     9781 gaagcgcagt ttctacactt tgcttgactc tccgatgttt ttccatggtt ttatcgtagg
     9841 ctctttggtt gttagcagct tgctgacttt gtttggcaaa attagccttt ctctgctcac
     9901 tatagctatc atagtctaaa tgctctacta gcgtttccgc ttctttacgg tgtttgacca
     9961 gtcgcaagtg aacaatagtg tctgccgttt cagaaagaaa gtcttcatca tgggaaatga
    10021 aaataacggt ttgcctggtc ttttgaatct ggccttttag ccaatcaact gtctcaaggt
    10081 ctaggtcatt tgaaggttca tctaaaaata gaatctcaaa gggtttggct aactcatgga
    10141 taagctgaat tttcaaagct tcgccccctg atagattgcc aatcttttgg tcacttgcga
    10201 aacgattgct atcaaaatgc aattcctccg ccaaacgata gaggatactg tagtctaaat
    10261 caatagaatc taaaaagaag tagtcgtgta aagttttctt tttcagctcc tcgggaagtt
    10321 tttgaggaat gtaggccagt gactgatagt cagattggat gtttcccttg atagtgaaat
    10381 cagacaaagc ttcccccatt aaaattttaa gtaaggttga tttgccattt ccttcttcac
    10441 caataatagc aaccttttcc ccgtcttgga tggtcatgct taggtcagat acaagatctc
    10501 gtaaatcttt gttttgtgtg atggttagat gattgatttt tatcatatga tttccctttc
    10561 tagaatgttc atagtgcata acaaaaagct ctactttacc tagtagagcc caaagtctat
    10621 gtcaaaaaaa ctctattaac atgccagaaa aagagcataa aagagcacac aaaaagagac
    10681 aaaaacaaga tctactaaat aaaggttctt tatttgatag acttagttgt tcatgtctcc
    10741 cttacctccg agtattagta tctttatatt atacctttaa ggaaattttg tcaacagaaa
    10801 actggaaatt ctatgctcta aaatccaaaa acaggtccat agagacttag tacgtgtttg
    10861 acatgctcgt aatggaattt atcatagttt cgccaagcag tgcgtgcttg atcgtttagt
    10921 tttaggctac ccagtccaat cagaagactg gtgggttggt aaaatttctc aagatcaatt
    10981 aagatactgt tgttcaactt ttccgttttt tgagctcttg catagtagtg tttagcagct
    11041 cttgtagtcg aatatcatct gccgtaccct gtttacagtt ttggtagctt ttatttaact
    11101 tggataggag ttgaatgagt ttcttgtctt ccatgtgagc atcctccttg atctgatgta
    11161 ctctttccct atagtatagc actaaaaaac aaaactgtca tagtaaatat gttaaaattt
    11221 tgaattttaa ttacaaagtt tggtgtgctg atttgtagcc ttttcatggt ataatcaaga
    11281 gagtaaatct ttatggagga agtatgaaat taaatattca agaaattcgt aagcagtctg
    11341 aaggtttgaa ctttgaacaa acgttagatt tagttgatga cctgcgtgca cgtaatcaag
    11401 aaattttaga tgtaaaagat atccttgcag ttgggaaagt acaatatgaa gaccgtatgt
    11461 atttcttaga ttatcaacta tcttatacca ttgttcttgc ttcgagtcgc agtatggagc
    11521 cagttgagtt agttgaatct tatccagtca cggaagtttt catggaaggc gcaactaacc
    11581 atctaaatca agaaatttta gatgatgact tggtcttgcc catcgaaaat gaggcgcttg
    11641 accttgctga gagtgtatca gacaatatct tgctaaacat tcctatcaag gtcttgacgg
    11701 ctgaagaaga agctggtcaa ggatttgtct caggaaatga ctggcaaatc atgacagagg
    11761 aagaatacca agctcaacaa gcagtaaaga aagaagaaaa cagtcctttt gctggcttac
    11821 aaggactatt tgacggagat gaataatggt cttgtcaaaa aaacgagcac gaaaggtgct
    11881 agaagaaatc attgccctct tcccagatgc caagcctagt cttgatttta ccaatcattt
    11941 tgaactcctg gttgcggtca tgttatcagc ccagacgaca gatgcagcgg taaataaggc
    12001 cacaccaggt ctctttgttg cctttccaac accccaagct atgtctgtag cgacagagag
    12061 tgagattgct tcacatattt ctcgcttggg attgtatcgg aataaagcta aattccttaa
    12121 aaaatgtgcc caacagttac tagacgattt tgatggtcaa gtccctcaga cacgtgaaga
    12181 attggagagt ttggcaggtg ttggtcgcaa gacagccaat gttgtcatga gtgtaggatt
    12241 tgggattcca gcctttgcag tggatactca tgtggagcgt atttgcaaac accacgatat
    12301 tgtcaaaaaa tcagcgacgc cacttgaggt ggaaaagcgg gtcatggata tcttgccgcc
    12361 tgagcagtgg ttagctgccc atcaggccat gatttatttt ggaagagcca tttgccatcc
    12421 aaaaaatcca gagtgtgacc agtacccaca attatatgat tttagcaatt tgtaagatgc
    12481 tacattgaaa ctttttgctt gattttaagc atgctttgtg ctatagtaaa tgataactaa
    12541 atattccttt aaacctgtcc cgtgaggcag gcaaggagcg cgataaagta gaagggtgaa
    12601 gtctatactg tgtgcagtag ggctcgcttg gctataaatt tcaagtctcc ttgtttaagg
    12661 agacttttct ttttggaggt ttgtcatgaa aacaaaagaa gttgtagacg aattgaccgt
    12721 caaacgagcg attacgcgta ttacttatga gattatcgaa cgcaacaaag atttgaataa
    12781 gatcgtcttg gctggtatta aaactcgtgg tgtctttatt gcccaccgaa tccaagaacg
    12841 tttgaagcag ttagaaaatc tttcagttcc tgttgtggaa ttggatacta aacctttccg
    12901 tgatgatgtt aaaagtggag aagatacttc tttggtttct gtcgatgtga cagaccgcga
    12961 agttatcttg gtggatgatg tgctctatac aggtcgtacc atccgtgctg ctattgataa
    13021 tattgtcggt catggtcgtc ctgcgcgtgt gagtttagca gttctagtcg atcgtggaca
    13081 tagagaattg ccaatccgtc cagattacgt tggaaaaaat atcccaacca gtcgttctga
    13141 agaaatcatc gtagagatga cagaacttga tgaccaagac agagttctga ttactgaaga
    13201 agcttagaaa gttaaaggag tagccatgtc agaaaatcaa caagcattga accatgtggt
    13261 gtccatggaa gacctcactg tcgatcaagt aatgaaattg atcaagcgag gaattgagtt
    13321 taaaaatgga gcccagcttc cctatgaaga ccatccgatt gtttccaatc tcttctttga
    13381 ggattctaca cggacacata agtcctttga agtcgcagag attaaacttg gattggaacg
    13441 acttgacttt gatgtgaaga ctagttcggt taataagggt gagacacttt atgacaccat
    13501 tttgactctg tctgctttag gagtggatgt ctgtgtgatt cgccatccag aggtcgacta
    13561 ctatagagaa ttgattgcta gtccaacgat tacgacttcc atcatcaatg gtggagatgg
    13621 ttcgggccaa caccctagcc agagcttgct tgatttgatg accatttatg aggaatttgg
    13681 ccactttgag ggtcttaaag ttgctattgc aggtgacttg gaccactcac gcgttgccaa
    13741 atccaatatg cagattttga aacgcttggg atctgaactc tttttcgctg gacctgagga
    13801 atggagaagt caagagtttg cagactatgg acagtttgta accattgatg aaatcattga
    13861 tcaggttgat gtcatgatgt ttctccgtgt gcaacacgaa cgccatgata gtggagctgt
    13921 attttcaaaa gaagactacc atgcccaaca tggcttgact caagaacgtt acgatcgttt
    13981 gaaagaaaca gcaatcctca tgcacccagc tccaatcaat cgtgatgtag aaatagcaga
    14041 ccacttggtt gaagcaccaa aatcacggat tgtccaacaa atgaccaatg gtgtctttgt
    14101 tcgaatggca atcttagaat ccgtactagc gagtagaaac gccaactaaa acacaagacg
    14161 ttaaaagacg ccagtgagcg tccacgagag gtgaaaatat gacaaaaaga attctagtat
    14221 tagaagatgg cacagttttt gaaggcaagg ccttcggagc agatattgat gtaacaggcg
    14281 aaatcgtctt taatacaggg atgaccggct accaagaatc cattacagac cagtcttata
    14341 atggacaaat cttgaccttt acttatcctt tggtaggaaa ttatggtatt aatcgtgatg
    14401 attatgaatc cattattcca acttgtaagg gagtcgttgt ttttgaagaa gcgcgtagag
    14461 ctagcaactg gcgcaaccaa atgaccttgg atgaattttt gaaagccaag aaaattccag
    14521 ggatttcagg aattgatacg cgtgctctta ccaagattat ccgtaagcat ggtactatgc
    14581 gtgcaacctt gacccatgtt ggggacagta tggaccatgt gacggaccag ctccaagcaa
    14641 cagttttacc gacagacaat atcaaacagg tttctactaa aacgtcttat ccagctccag
    14701 gagttggttt gagcgtggtg ctagtggact ttggtctcaa gcactcaatc ctacgtgaac
    14761 tttctaaacg caactgtaac gtgacagttg ttccttattc gacaacggct gaagaaattc
    14821 tccatctcaa tcctgacgga gttatgttgt caaatggtcc aggtaaccca gaagacgttc
    14881 cacaagcact cgacatgatt cgcggtgtac aaggaaaaat tccaatcttt ggtatttgta
    14941 tgggacacca actctttgca atggcaaacg gggctaagac ctataagatg aagtttggcc
    15001 accgtggatt caaccatgcg gtacgtgaaa tcgcaacagg acgagtagac ttcaccagcc
    15061 agaaccatgg ttatgcagtc agccgcgagg atttgccaga gcacttgatt attacccacg
    15121 aagaaatcaa tgacaagtca gtggaaggtg tgcgccacag ataccaacct gctttctctg
    15181 ttcaatacca cccagatgca gctcctgggc cacacgacgc tagctaccta tttgacgagt
    15241 ttatcgagat gatggaagtt tttaaacaat caaactaaga acgagtaaaa gctcgtcgga
    15301 gaatttatgt aactgaacac ggacggaaag ctcagaatgt agagaaacca acttggattg
    15361 tcaatccttc cttgatttcc taaaattcaa tcgctttcta ttcgtccttt gtatcttatt
    15421 taatgtcgcc ctgagaggcg acgaatagaa aggagaaggg tgctccgtat ttgctgaact
    15481 gaatacgggc tacggacggt gctaaaaaga tagttattcc tagaactgac agttcttcgt
    15541 cataactcct attttagctt tgtccgcttg acacccttaa tatcttatat atgcctaaac
    15601 gtactgatat tcaaaaaatt atggtgattg gttctggtcc gattattatt ggtcaggctg
    15661 ctgagtttga ctacgctggg actcaggctt gcttgtcgtt gaaagaggaa ggttatgagg
    15721 ttgttttggt taactcaaat cctgcaacca tcatgacgga caaggaaatt gctgacaagg
    15781 tttacattga accgattaca cttgagtttg tgacacgtat tcttcgtaag gaaggtccag
    15841 atgccttgct accaacactc ggtggtcaga caggtctcaa catggccatg gaattatcta
    15901 aaaatggtat cctagacgag cttggcgttg aacttctggg taccaaatta tctgccattg
    15961 accaagcgga ggaccgtgac ctctttaaac aattgatgga agagcttgaa caacccattc
    16021 cagaatctga aattgttaac acagtagaag aagcagttgc ctttgcagcg acaattggct
    16081 acccagtcat cgttcgtcca gcctttaccc ttggtggtac tggtggtggt atgtgtgcca
    16141 acgagaaaga attgcgtgaa atcactgaaa atggtttgaa attgtcacct gttacccaat
    16201 gtttgattga gcgttcgatt gccggtttca aggaaattga atacgaagtg atgcgtgact
    16261 cagctgacaa tgccttggtt gtttgtaaca tggaaaactt tgacccagtt gggattcaca
    16321 caggggattc cattgtattt gcccctgcgc aaaccatgtc agactatgaa aaccaaatgc
    16381 ttcgtgatgc gagcttgagc attattcgtg ccctcaagat tgaaggtgga tgtaatgttc
    16441 agctagctct tgatcctaac agcttcaagt attatgttat cgaagtaaac cctcgtgtat
    16501 cacgttcgtc agcccttgct tctaaagcga caggatatcc gattgctaag ttggctgcca
    16561 agattgcagt aggtttgacc ttggatgagg ttataaaccc agttacaggt tcaacctatg
    16621 ccatgtttga accagccctt gactacgtag ttgctaagat tccacgtttc ccatttgaca
    16681 agtttgaaaa gggtgaacgc cgtctcggta cacaaatgaa ggcgactgga gaagtcatgg
    16741 caatcggtcg taacatcgag gaatctcttc tcaaggcctg ccgctccctt gaaattgggg
    16801 tgcaccacaa tgaaatacct gaacttgcag cagtttctga tgatgccttg attgaaaagg
    16861 ttgtcaaagc ccaagatgac cgtctcttct acgtatcaga agccattcgt cgtggctaca
    16921 cacctgaaga aattgcagag cttacaaaaa ttgatatctt ctatcttgat aaactcttgc
    16981 atatctttga aattgagcaa gaattgggtg ctcatccaca agatttagaa gttttgaaaa
    17041 cagccaaact taatggtttt tcagaccgta agattgctga actctgggga acgactgatg
    17101 ataaagttcg ccaacttcgc ttggaaaaca agattgttcc agtttataag atggtagaca
    17161 cttgtgcggc agagttcgac tccgaaacgc catatttcta ttcaacctat ggttgggaaa
    17221 atgaatctat cagatctgat aaagaatctg tacttgtcct aggttcaggt ccaatccgta
    17281 tcggtcaagg ggttgagttt gactacgcaa ccgttcactc tgttaaggct atccaggcag
    17341 ctggttatga agctatcatc atgaactcaa acccagagac cgtttcaaca gacttctctg
    17401 tatcagataa gctttacttt gagccattga cattcgaaga tgttatgaac gtcattgact
    17461 tggaacaacc aaagggagtt atcgttcagt tcggtggtca aacagccatc aaccttgcgg
    17521 agccattggc aaaagcaggt gtgaccatcc ttggtacaca ggttgctgac ctagatcgtg
    17581 ccgaagaccg tgacctcttc gagcaagctc tcaaagaatt ggatattcca cagccaccag
    17641 gacaaacggc taccaatgaa gaagaagcag ctcttgcagc tcgtaagatt ggcttcccag
    17701 ttcttgtccg cccatcttat gtacttggtg gacgtgccat ggaaatcgtt gaaaacgaag
    17761 aagaccttcg ttcttacatg cgaactgctg ttaaggctag tccagaccac ccagttcttg
    17821 tcgactctta tatcgttggg caagagtgcg aagttgatgc catttcagat ggtaaaaatg
    17881 tactcattcc tggtatcatg gagcatatcg aacgtgctgg tgtccactca ggtgactcaa
    17941 tggctgttta cccaccacaa accttgtcgc aaaaggttca ggagaccatc gcagactaca
    18001 ccaaacgctt agcaatcggt cttcactgcc ttggaatgat gaacatccag tttgttatca
    18061 aggatgaaaa agtctacgtt attgaggtca atccacgtgc cagccgtact gttccattcc
    18121 tatctaaggt aaccaatatt cctatggctc aagtagcgac caaactcatt cttggtcaaa
    18181 gtttatcaga acttggctac caaaatggac tttaccctga aagcacccgt gttcatatca
    18241 aggcacctgt cttctccttt accaaactag ctaaggtaga cagcttgctc ggtcctgaaa
    18301 tgaagtcaac aggtgaagtt atgggttctg atgctacttt ggaaaaagct ctctataaag
    18361 cctttgaagc ttcttatcta cacttgccaa cttttggtaa tgtcgtcttt accatcgctg
    18421 atgatgccaa agaagaagcc ttgaacttgg ctcgtcgttt ccaaaacatt ggttatggaa
    18481 tccttgcgac agaagggaca gcagccttct ttgctagtca tggcttgcaa gcccaacctg
    18541 ttggtaagat tggtgatgac gataaggata tcccaagttt tgtacgcaaa ggaagaattc
    18601 aagctatcat taacacagta ggaacaaaac gaactgctga cgaagatggt gagcaaattc
    18661 gtcgttcagc cattgaacac ggggtgcccc tcttcacagc gctagataca gctaatgcca
    18721 tgcttaaggt acttgaaagt cgtagctttg ttacagaagc gatttaaata gaaaaaataa
    18781 gatatagcag cctgaattta gaacag
//
LOCUS       DAVMCG010000040        18437 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVMCG010000040 DAVMCG010000000
VERSION     DAVMCG010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.041"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..800)
                     /gene="lytB"
                     /locus_tag="VYP66_001645"
     CDS             complement(<1..800)
                     /gene="lytB"
                     /locus_tag="VYP66_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1851162.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGK"
     gene            complement(842..1780)
                     /locus_tag="VYP66_001646"
     CDS             complement(842..1780)
                     /locus_tag="VYP66_001646"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1851163.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEYAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1791..2591)
                     /locus_tag="VYP66_001647"
     CDS             complement(1791..2591)
                     /locus_tag="VYP66_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1851164.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2841..3221)
                     /locus_tag="VYP66_001648"
     CDS             complement(2841..3221)
                     /locus_tag="VYP66_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1851165.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3279..3638)
                     /gene="rplT"
                     /locus_tag="VYP66_001649"
     CDS             complement(3279..3638)
                     /gene="rplT"
                     /locus_tag="VYP66_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1851166.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3690..3890)
                     /gene="rpmI"
                     /locus_tag="VYP66_001650"
     CDS             complement(3690..3890)
                     /gene="rpmI"
                     /locus_tag="VYP66_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1851167.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3923..4453)
                     /gene="infC"
                     /locus_tag="VYP66_001651"
     CDS             complement(3923..4453)
                     /gene="infC"
                     /locus_tag="VYP66_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1851168.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4469..4600)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4760..5941)
                     /locus_tag="VYP66_001652"
     CDS             complement(4760..5941)
                     /locus_tag="VYP66_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851169.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYFNSQTANSVS
                     LERELETRLVDRERVINEYEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKDYEFVSNDPTASSELKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEAIIPTLFVIGIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYSIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     gene            complement(5945..6532)
                     /locus_tag="VYP66_001653"
     CDS             complement(5945..6532)
                     /locus_tag="VYP66_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851170.1"
                     /translation="MLQLTHVTLKTRQVILQDADFTFKKGRFYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            complement(6931..9171)
                     /locus_tag="VYP66_001654"
     CDS             complement(6931..9171)
                     /locus_tag="VYP66_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1851171.1"
                     /translation="MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCL
                     FFQFPWKSAGKVLVICGVFGFWFLFQNWQQSQASQNLADSVERVRILPDTVKVNGDSL
                     SFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLPLVYDLRKNIKGLTVLSLLITGLFFLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            complement(9155..9805)
                     /locus_tag="VYP66_001655"
     CDS             complement(9155..9805)
                     /locus_tag="VYP66_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEV1851172.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSIDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9873..10442)
                     /locus_tag="VYP66_001656"
     CDS             complement(9873..10442)
                     /locus_tag="VYP66_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851173.1"
                     /translation="MESIFVKLAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10619..11044
                     /locus_tag="VYP66_001657"
     CDS             10619..11044
                     /locus_tag="VYP66_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEV1851174.1"
                     /translation="MLIGIPKEIKNNENCVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            11045..11458
                     /locus_tag="VYP66_001658"
     CDS             11045..11458
                     /locus_tag="VYP66_001658"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEV1851175.1"
                     /translation="MGAHFLTKQAGGSGVLLGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLMSNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            11404..11730
                     /locus_tag="VYP66_001659"
     CDS             11404..11730
                     /locus_tag="VYP66_001659"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851176.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(12097..12357)
                     /locus_tag="VYP66_001660"
                     /pseudo
     CDS             complement(12097..12357)
                     /locus_tag="VYP66_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12360..12860)
                     /locus_tag="VYP66_001661"
     CDS             complement(12360..12860)
                     /locus_tag="VYP66_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851177.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            12896..13075
                     /locus_tag="VYP66_001662"
     CDS             12896..13075
                     /locus_tag="VYP66_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851178.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLRPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(13053..14021)
                     /locus_tag="VYP66_001663"
     CDS             complement(13053..14021)
                     /locus_tag="VYP66_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1851179.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14107..14322)
                     /locus_tag="VYP66_001664"
     CDS             complement(14107..14322)
                     /locus_tag="VYP66_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1851180.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14331..15185)
                     /gene="cvfB"
                     /locus_tag="VYP66_001665"
     CDS             complement(14331..15185)
                     /gene="cvfB"
                     /locus_tag="VYP66_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1851181.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15245..15802)
                     /gene="frr"
                     /locus_tag="VYP66_001666"
     CDS             complement(15245..15802)
                     /gene="frr"
                     /locus_tag="VYP66_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1851182.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15811..16548)
                     /locus_tag="VYP66_001667"
     CDS             complement(15811..16548)
                     /locus_tag="VYP66_001667"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1851183.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16632..17966)
                     /gene="trmFO"
                     /locus_tag="VYP66_001668"
     CDS             complement(16632..17966)
                     /gene="trmFO"
                     /locus_tag="VYP66_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1851184.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(18211..18405)
                     /locus_tag="VYP66_001669"
     CDS             complement(18211..18405)
                     /locus_tag="VYP66_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1851185.1"
                     /translation="MEAEAIRRNCERGAIFSGKIKYHEDSQFKGDHYVECYAVLDNTV
                     IARDRITVPIDPLCGKDFIE"
BASE COUNT         5312 a         4174 c         3408 g         5543 t
ORIGIN      
        1 attttcccat caaatttgag ataaaaccaa gattccttat cccaaatcca ttcattggct
       61 gccatgtagc caccggattt tagataataa tagtgaccat tctcgaaaat ccattcttta
      121 tcagcatagt ttccattttc tttgatgtaa aaccaagatt ggtattgttt gtcaaaaagc
      181 caaccttgct gtactttggc accactagca ttcacataag cttgattaat ccactgactt
      241 gtcagtagat aaccaccgga tttgaaataa tagtccttcc ctttaatttg gagccattct
      301 ttctctgcgt gctgtccatc tgctttgata taaaaccaag catcgtattg agaatcatag
      361 acccagtctt ctattacttt ggcacctgtt gcaccaacat aggaagttcc tacccaagca
      421 tttcttttca tctttccatc ttggtcaaga taataaaagg ctcccttgtc ttctacccat
      481 tctgatttgg ccatatagcc accagatttg aggtaaaaat agtcgtcacc ttgctttagc
      541 cattcatttt cagcatagtt agcatctgct tttatataga accaagattg ataatgagta
      601 tcaaaaaccc actcatttgc tgcttgactg ccatcttctt tcagatactg ttttccttgc
      661 caagtaccat cactagccat tgcaccctct ggactagcta agaaaaatag cagagctaaa
      721 aaaataaatc ttactttctt cattaacctt cttcctctgt tcttatttat tttattgtac
      781 caaaattctc ctaaattcat attacaaact aataaaaaat caagaacaga ttgattgcag
      841 tttacctcag agactctttt acttcctgac ggagttcttc cagactgcta ataccgtatt
      901 tatccatgac ttttggtaaa ttttcgatga tgtcagggca ggcataagga ttggtaaagt
      961 tagctgttcc aactccgata gcagatgccc cagccagata catttctagg gcagcttcag
     1021 ccgaatccac tccccccatt ccaatgatag gcaggtctgt tgtttgggct acttggcgga
     1081 tgagtttgag ggctactgga aagactgctg gacctgacat tccacctgtt ccattggcca
     1141 agattggttt tctggttttg aggtcaaagc gcattccaac cagagtattg atcatggtca
     1201 agccacttgc tcccgcatat tctgcagctt ttgcgacagt aacgatatcg gtcacactcg
     1261 gggttaattt gacataaact ggcacttctg aggcttccac agctgctttc accacatcat
     1321 aagccaaatc tggatcttga ccaatcaaaa gtccatgatt acagtggtca acattgggac
     1381 aagaaatatt gagctcgata gcttttacat tagttgcctt ggaaatccca tgagaaacag
     1441 ctgcatactc ttgttttgaa aaaccagcta cattggcaat aataggaaga tttggatatt
     1501 ctctttccag ccaaggtagc ttttcagcca aaacaacctc taaaccagga ttttgcaagc
     1561 caattgcatt gagcatacca gcaggcgtct ctgccactct tggagttgga ttcccaaaac
     1621 gtggttcaag ggttgtcgcc ttgatcataa tagaacctaa aaggtctaaa tcatagtact
     1681 tggcatactc ttgtccaaag ccaaaacagc ctgatgctgg aataatcgga tttttcaaat
     1741 ccaaaccagg tagagacact tgtaatcgat ttgtagtcat aattttctcc ttataataca
     1801 actgttcctg tgcggaaaac aggaccatct tcacagacgc gttggctgac cgtctcgctt
     1861 tctggtactt ttagaacaca ggcatagcaa gctcccatcc cacaagccat acgagattcc
     1921 agagataaat aggctcttgg gtgatcatca aaggtttgat tgatatactt catcattcct
     1981 ggagccccac acgagtaaac agcatcaaac tgactatcta aatcattgat aacaacggaa
     2041 acatttccct tgatgccata agaaccatca tctgtcgtta caaagacctg accatactga
     2101 gccaattccg ttttcaaaat aacagcatcc ttattagcaa aaccgaggac tgtcactact
     2161 ttcactccac gttcatgcaa ttccttggcc acctcaagca agggtggaac accaatccca
     2221 ccaccaacaa ggagaacctg attctgctca tcaaggtcag acaagtcaaa accatttccc
     2281 tgaggcccca tcacatcaag agtgtctccc tgacttaagg ttgaaaaaat tgcagtccca
     2341 gctccctcaa tccgataaat gaggtgacac tgcttgtttg ccttgtcaat agacgaaatt
     2401 gaaataggac gacgtaagag atgggcatcg tctggtacac gcagatgaag aaattggcct
     2461 gctcgcatgg cttcaaccat ttctccttct aggactaatt caaagattgc tggcgcgatt
     2521 tcctcttgtg caaccacctt catggtttcc aaccgaatga cacccaaacg cttcttacat
     2581 gtgagattca taacttttcc tccttaaatt ttaaggggac cagataaaga aaagaccttg
     2641 ctagtgcaag gcctcagtta aaatcgtaca acacaagaga gcacactcaa aaggtctcct
     2701 ctagaaaatt gcactattct tttatctgac accttgtgag tctctctgga ctccccttaa
     2761 aggttgaatt tttattagta tactctttca gctaaaaaaa gtcaagtaga aaacgaatat
     2821 tctacttaac ttgcacgaaa ttatttttca cgaatgactt cgaccttata tccatcaggg
     2881 tctttaacaa agtaatagtt tggtgtagtt cctggtagac catttggctc agtcacttca
     2941 tagccttttg cactgtgttc ttgatgaagt gcctcaagat caggtgtact gagggcgata
     3001 tgggcaaacc catcaccaac cacatacgga ccgtgatcgt agttataagt caactccaac
     3061 tcataatcat caccctcaag acctagatag acaatcgtga aggcatggtc tggaaaatct
     3121 ctgcgacgca attctttaaa accaaaagca tcttgataaa atgcgattga tttttcaaga
     3181 ttttctactc gtaagcaagt gtgtagcatt tttgaagcca tatctttctc ctttattttt
     3241 aaaaagactg gacaatcctg ttccagtctc atcagttgtt atttaccaag ttttgcttta
     3301 gctgcatctg caagagctgt gaaagctact gcatcgttaa cagccaagtc agcaagcatt
     3361 ttacggttaa cttcgatctc agccaatttc aaaccatgca tcaattgtga gtatgaaagt
     3421 ccgttcatac gagctgccgc attgatacga gtgatccaca atttgcggaa gtcacgtttt
     3481 ttctgacgac ggtcacggta tgcatagtag taagagttca ttacttgttc ttttgcagta
     3541 cggaacaaga tgtgtttagc tccatagtaa ccttttgcta atttaagaat acgtttacga
     3601 cgtttgcgtg atacaacgcc acctttaaca cgtgccatgt tttatttcct ccaaatattt
     3661 cctagaattg tttacttaca gtcaagctat tatttcaagc gagtaagcat tgctttgata
     3721 cgtttgtaat ctcctgaatg caccatagat gctttacgaa gatgacgacg ttgtttctta
     3781 gtttttccgt ggaaacggtg agaagtgtaa gcacggaaac gtttaagtcc accagaacct
     3841 gtacgtttga aacgtttagc tgatgcgcgg tgtgtttttt gttttggcat gattttttct
     3901 cctttattta actttctgac aattattttt tgtcagtcgc tggcgccaat tgcatgaaca
     3961 tttgacgtcc atccatttta gcacgttgtt cgatgatggc aatatcttga gttgcttcag
     4021 caaactcggc taaaactttt gcaccaatct ctttatgggt aatcatacga cccttaaagc
     4081 gaatagatac cttaacttta tttccttttt caaggaactt acgtgcatta cgaagttttg
     4141 tatcaaagtc acccttgtca attgttggac ttagacgaac ttctttcaca gtaacaacgc
     4201 tttgtttttt acgttgttct ttttgcttct tctggtactc aaatttgaac ttaccgtagt
     4261 ccataatttt tgcaacaggc ggtttggctt ggggttgaat caatactagg tcaacattag
     4321 cgttatcagc caaagcttgc gcttcactga gtggcttgat gcctagctgt tctccctcaa
     4381 gaccaatcaa gcgaacttca cgtacacgaa tctcatcatt gatgaataag tcttgctttg
     4441 ctatggtttt cacctctttt gttttattag agaaaaacaa tagcggactc gtaaatatac
     4501 aagcccgcac gttatgatag cgtttcttcg aaacttttca tccgtagggc caggcaactt
     4561 aatgtcacaa ggcgagaagc tctcacttct gcttttctca acttttatat gataccaagt
     4621 tttctagctc ttgtcaagat aaaaagttat tttttgaaaa gtttgtgttt gtattttggt
     4681 ttggttttcg aatcaaaaag agagaaccaa gttgattctc tccctatgtt agtttttctt
     4741 tagcttccct ataggaaaac taaactttaa aaacttcctt tttacgtgaa cttccccagc
     4801 tttcgataaa tagaatcccc actaacaaaa ggataatcag gcaaggaagt aagaccatcc
     4861 ccatgctcca atttagatcg acattatcaa tctgcttaga taatcttcca gataaaatct
     4921 ccactgaacg caagtaagta aagggaatca gatgtgcaat cctttgaaga ggctgaattg
     4981 tttggatgcc aaacaataag ccaacaatcc caatgagtga aagaaagagg acaggcattt
     5041 tttgcttgaa aaaataagca atcaagtaca caacttccac aatgacgata aaggctaaga
     5101 aagctaagag taagccagga aataatacat cttgtatttt cccaatagtt acttcttgat
     5161 tcactaagct ataaattgag tagggataat ctaactgtcc aaaaccactt atcagacttc
     5221 ccactagaaa agaaaagcca cagattccga taaacagcac agttacatat cccactccaa
     5281 ctccaagaga ggatattgca aatgtcactt ttgaaacagg atataagtga gctgtgtcca
     5341 gatgattttg atatctttct gcaaatagtt gtgttagcat aaaaataata ccaatcacaa
     5401 ataaggttgg gatgatagcc tctaaaatcc agacaatctg atcaatcccg tgggtcggaa
     5461 actccaaagt atgtgctttt atgttcaagg gatacagggc ttgataaatc ttccgttcgc
     5521 ggtcaacccc catttttaat tcagagctag cagtcgggtc atttgataca aattcataat
     5581 ctttctcttc atcttgccac tgcagatagt aggcctcttt ccagcgccct tcttttagta
     5641 aagttagaat ttctgtcttt cgcgtcaaaa gatttttttg cacgtctaaa ttatttttag
     5701 caaactggta ttcctccgag ctggtatcag acatttggga gagtttctct tcatattcat
     5761 tgatgactct ctcacggtct acaagacgag tttccaactc tctctccaag ctgactgagt
     5821 ttgcagtctg actattaaaa taaaaagtaa caccgagtac agatacaaat aaagctaaga
     5881 taatccagtt taagcggctt ttgaaaactt ttttcaataa aaatagacta acatctttca
     5941 taaactaaac ctcttctatc tgcccctgat gaatggttac tactctatcg cagatatcaa
     6001 ccaactcttc cttatagtgg gaacttaaaa gaaccagctg ttcttgtcta tcgatttgtg
     6061 ctaacctatc aaaaaacttc tgtcgataat actcatctaa gccatttgta atctcatcca
     6121 tgagccagca tttggcctga ctgagaaaat acatagcaat caccaagcgt tgcttcatgc
     6181 ctaaggaata cttgcggatg ggaagactga tatagtcagc catttcccag taggcgattt
     6241 catctctcaa gtttaggtct gacttccaga tgtttttgat aagacgaagg tagtccatcc
     6301 cacttaagtt tccatccagc cattcaatac tctcataata aaataaagaa ggaggagctg
     6361 cgatatttcc actacttatg ggaattaaat tgctaatggc acggaacagg gtcgtctttc
     6421 cagagccatt gatagcaaga agaccataaa acctaccctt tttaaaggtg aaatccgcat
     6481 cttgcaagat gacttgtcgc gtttttaagg tcacatgagt aagctgcaac atatctagcc
     6541 ctcctttttc tcactcttta agaattaata gcctccgctg taatagttta tgatctcata
     6601 acgaccgtag ttccagccag aaccaactgg atactcagaa tagctgtaat aacgagacca
     6661 tgacggaacg ttagtatgtc tatatccatg gaaattcata ctagacttat agaagatatt
     6721 ccaatcatac cgatactttt aagaacactc ttagcagata cactggactg aagaagacca
     6781 atagattata aactaactaa taaaataact tttgctgatt tttaatgatt ttatatcctc
     6841 aatattgaat acgttttcat tataccattt ttatcattat tatgcaacaa atttttagtt
     6901 tatttcacta atctacaaca tttatccttc ctatcgaaca ctttcgattt tccaactatc
     6961 caacccctta aaacgtatag ctccttgctg gtcagttcga taaactttgc tattgatacc
     7021 ttccagtcgt gtcaatgttt cctgatgggg gagtttcatt cgattgctct ttccaactga
     7081 gataagagta agctctggtt tgagtttttc tagaaaggct ggacttgatg attttttatt
     7141 gccatgttgg ctagctttca aaacatttac tttcaagtct ggatagtgct tcagcaagtc
     7201 cttctctcct ttctcctcca aatttcccgt gaagagaaat tgcttatcca agaatttccc
     7261 atacagaact agggtatcat cgtgtcctcc atctcccatt ttccttggag atagaacttc
     7321 taactgactt ccaaaaatgg gcaagttctc ccctactatc atactacgca cctttgtttg
     7381 agtcgcctgt agttctgcca caaattcctt ctgtttcaga ctgtcttttg atactagaat
     7441 ctcccctaca tggaaagcct tggtcatctc tgacaaatct ccaacatgct ccttgtccgt
     7501 gttagtcaaa attagctggt caatcttagc tactccccga cttttgagat agggaatcaa
     7561 ggttcgctgg gcattgctgg tcgtcatctt ttcttgccat tttttgattt tcttataaga
     7621 ttctgcctta ccacctacat ctatgagaat ggttttccca gttacatccc gtaggaaaat
     7681 actttctcct tgccccacat ccagcatggt gatttcattt tccagtggat gcttggtaag
     7741 gaaaaagaga cctgtaatca ataaactcaa tactgttaat cctttaatgt ttttcctcaa
     7801 atcatagacc aaaggcaaag aaattaacaa taggattaaa agccattcat tgggttgtcc
     7861 aaagactaga ggcctacttg ccacctgtga gaccaagcga ataatgccct ccaaccattc
     7921 aaagataaag ttcagctgaa tgactggata gagaaaggaa aggacaaata agatagacaa
     7981 gagcggtaag aaggtcaagt caaatagaaa ggaaaagaca aaggtcaaaa ggatagacca
     8041 aggttgaaat tccgcaaaat agaaggatag aatgggcaat atgcccaagg agatgactag
     8101 actttcacta gcaacagcct tgagcccctc cccttctttg ctggtcatgg tcaggataaa
     8161 agcataagcg caggacaaga ctcctcctgc tgtcaagaaa aagtttggca tgacaataaa
     8221 gaggagaaac actgtcaagg caaaattatc caagccctta accccatgtt gagccagtag
     8281 cttttgcaag agactgcgaa taaccgatgc tgaaaatcca gttagtcccg catagataag
     8341 ggaaaaggga taagtcagcc atttcaactt ttcttgggtc aagcccaatc gcaagagaag
     8401 tttcttaaat ccattcatga aaaaacctac ctgcatgcca gatagggcaa agaggtggat
     8461 aattcctaga ctggaataaa gctcattcat ctcctcaaag tcggtgtcca gatgtcccag
     8521 caagagtcct gtcatgtaat tgcgcatagg gtctggaaag tgcgtcttaa tccaaaccac
     8581 agcctttcga cgtaaactgg acaagttttc tcctatatcc caactgccaa tcttttgaag
     8641 tgactggatt gttttgatat tgagagtctg gtaaattccc tgagtcttca gataggcttg
     8701 gtaattaaag ccaccaaaat ttctctgccc ttctggctcc gaaagcttcc cttctagtcc
     8761 tatctcatgc aggtcggtta aagcttgaaa ggcttctttc tcctcctcgg actggagttt
     8821 ataatagact tgaaaaatgc gtccatcagc cttgccgcga aaggacagac tatcaccatt
     8881 gaccttaaca gtgtcaggca gaatccgtac cctttcaaca gaatccgcca gattttgact
     8941 cgcttggctc tgttgccaat tttgaaacag aaaccagaag ccaaagactc cacaaatcac
     9001 taaaactttg cctgctgatt tccatggaaa ttggaaaaag agacagacta gcagaaaaac
     9061 aaagcccaac aaagcaagat aggatgctga gaaaatagcg taataaaacc aaagtaacaa
     9121 aaaactcagg taaattaggg gaatggggat gttcttaatc cactgtaaca tagtctttta
     9181 gcttttctat ggtcttagca ccaatgccag agaccttctt gagttcatca atcgacttga
     9241 atttcccatt tgcctcacga tggtctataa tgtcctgagc tcgttttcct cccagtccct
     9301 taacctgttt aagctcttcc agactggcct tgttgagatt gaccttcttt tccttgcttg
     9361 ttgaagaagc tgtccccgaa ccagtctgtt gactaactgc ttcttctccc ttagtaggaa
     9421 cgtaaaccag agcctcatca ctaactttct gagctagatt gagcgacttg ctgtctgctt
     9481 gctctgtcaa gccaccagcc ttctgaacag catcattgac tcgactacct acaggcaagt
     9541 cataaatccc tggcgatttg acagcacctt tgacatctac tgtgattaga tcttgttcaa
     9601 ggggttcttc cttctcttcc ttgttcactt ccttttcgga taccaaatcc ttggaaacag
     9661 ctgcaacttc agcctgcaaa ttcgtttcct ttacaggtgt ttgtggagct ggctttagca
     9721 ggaaaaatcc gcctacaagc aagcccagac cagtacagat gacgatgatt ttatactctt
     9781 tgattttctc gataattgct tccatatttt ctcctctctt agattattcg taagaggaag
     9841 aaaaaacagt cgaaaaattt cttttcaact gcttatttat ttgcaaaata gtcttccttg
     9901 gtcaagacat aatgaactct tgtcacgatt cggccttttt catgctggtc catacaagca
     9961 tatggttctg catgggaaaa acgcatgcct gatttctcca tgacctttcc tgacgcagga
    10021 ttgtccttat cgtgaagggc agtcaactta ttcatcccta tcttctcaaa agctagctca
    10081 atcacagcac gattggcttc tgtcgttaat ccttgattcc aatacttttt attgataatg
    10141 tagccaatag ctgccttctt aagaacagaa tcaatcttgt gcaagtcaat ggttccaata
    10201 aactgaccat tgctttttag ttctattccc caacgtccca agggattagc caaatagaac
    10261 tgagcaatgt tattcttggt ttcttccaag ctttgattgg ttggaaaagt gtaacgtgta
    10321 ttacccttgt ccgaggcata gtcaaacatt gcttccgcat catccaaagt tacaggtcta
    10381 agcaataaac gctccgtttc tatagacgga tactgggcaa gttttacaaa aattgattcc
    10441 atacttttcc aaccaatcaa agcttgattt tcactagtct agcataaaaa atttggatga
    10501 caagtttttc ttgatttttg aagcggtttc atatacaatg aaaccgtcac atttttgatt
    10561 tatgaactgg aatgtgacaa ccaaaacaag accgtcaatt gaaaggtagg ttatctcaat
    10621 gttaatcgga atcccaaaag aaattaaaaa taacgaaaac tgtgtcgccc tcacacctgc
    10681 aggtgttcat agcttagtta gtcgtggtca tcgtgtcctt atcgaaacaa atgctggtct
    10741 cggttctggc tttactgatg ctgactatca aaagcaagga gctgagattg tcgctactgc
    10801 tggtgaagct tgggcagcag agttggttgt gaaagtaaaa gaacctttaa gttctgaata
    10861 cggttacttg cgcgacgatc ttcttctctt cacctacttg cacatggccg ctgctccaga
    10921 attagcagat gctatgttag cagcaaaaac aacaggaatt gcctatgaaa ctgttcgtga
    10981 caatcaagga caactaccgc tcctcgttcc tatgagtgag gttgcaggtc gtatggctgt
    11041 ttaaatcgga gctcacttcc ttactaagca agctggtggc tctggtgttc tacttggtgg
    11101 tgtaccaggt gttccaaaag gaaaagtaac tatcatcggt ggtggtgtcg tcggtacaca
    11161 tgctgcccgc atcgcccttg gtcttggtgc tcaagtgact attttagata ttagtgccaa
    11221 gcgtctctca gttctagaag aagtctttgg aagtcaaatt caaactctta tgtctaattc
    11281 attcaacatt gaagcaagtg tgagagatgc tgatgtggtg attggagcca ttctcatccc
    11341 tggtgcaaaa gcaccggaat tggtgacaga tgagatggtc aaacaaatgc gtccaggctc
    11401 tgtatcgttg acgttgctgt tgaccaaggt ggcgttatcg aaacagctga ccgtgtgaca
    11461 acgcacgatg aacccgtcta tgaaaaacac ggtgttctcc actatgccgt tgccaatatc
    11521 cctggtgcgg ttgcccgcac ttcaaccatc gccctaacca atgtcactct tccttatatc
    11581 gaagctttgg ctggcaaagg attcgcacaa gcaatctctg aagatgaagg cttgcgtcaa
    11641 ggtgtgacca cttatcaagg ttacttgact agcctaccag ttgctcaagg acttaatcgt
    11701 gactacactg atatcaatga tttagtataa attttgaaaa gaaaagggtg acttcgcaag
    11761 tcctacccac tgtgctttgt gtcatcagct attacatcgt tggtttattg tactgtatac
    11821 tttgcaactg gagactttcg ttccagactc aattgtgcat aagaaactct aaattgaata
    11881 aagtcaacag agtttcgccc aaccacttcg tcttgtaatg acaattatat aaaccaaagg
    11941 aagctgagct ctttagtccc agcttctttt tatatataaa attttacccg tgcaaagaca
    12001 gggccttagc agacttcttt tttacttcgt tcacccttgc tttttctttt taggtttggg
    12061 cgttggcagt tggttataca tagctaaaat caggtcttat agaaacatct tattatcaag
    12121 ttcttccact caaatcattt ctttggcacc tttgtatgga aactcaaaag aagattggtc
    12181 aatcttatct aagactgctt gcacgggttt aactaaaaag cgatcatcat aaatgccgcc
    12241 aataatcttg ccgcggaagt aaagaatata ctcccccatc atggaacggt aagtcacatc
    12301 atctaatcct gataattgtt ccaaaacaaa ttccaaatag ttcttacttg atgccatttc
    12361 taatcttcta ggctctgttc agcgataaca accgtataga gttcttgctt aacctcgcat
    12421 ccaattgatt taaaaccctg cttttcccaa aaatgctgag attgcggatt tcccttaaca
    12481 taagccaaac gtgcctttcg aaagttctta gcaaaataag ctagtgcttc tgtcacaata
    12541 tgactaccaa tccctttcct ctgataggct tgatcaacca taaacaaacc aataaaaaca
    12601 gtctcctcat caggataggc atagacaaaa tccataacag ccacaaggtc agatccattc
    12661 caaaatccaa caaaaaactt atcagcctta gctttacctt caggtagaca aagcatgtcc
    12721 tcttttacag ttgcaaaatt tggctctggt ggacaatgct gaaaatacag aggattactt
    12781 tcatataaag ataaaatact tggaatatcc ttttcagtta gtatcctaca actgtaatac
    12841 ttagatagtt ggtcaatcat cttttcaaat tcctactttc ttgtgccctg tgattatgac
    12901 acaggaagat gcactgatcg tcatcagcca cataaaagtt ctttccatcg tgcctaatcg
    12961 ttgtctcaga cctttggata aaacctttag cctatacaac tggattttcc tctctcaaaa
    13021 gtatattctt ttgcaggcga acttcctcaa aatcagtcgt gtgcaacttc agtagaatat
    13081 tcataggctc ggataatctg agcgacaact ggatggcgaa ccacatcctt ggctgaaaaa
    13141 tgaacaaagt caatctgatg gatgttcttg agtttctctt gagcatcaat caaaccggac
    13201 ttgacattac gtggcaggtc aatctgactg atatctccat tgacaatcat cttagaatga
    13261 aagcctaaac gcgtcaagaa catcttcatc tgcatgatgg tcgtgttttg cgcctcatcg
    13321 agaatgacaa aggcatcatc caaggtccgg ccacgcatat aggcaagggg cgcaatttcg
    13381 ataatttcac gctccatgag acgagtcgtt tggtctttcc caagaatttg atacaaggca
    13441 tcgtaaacag gacgaaggta aggatccacc ttctccttaa gatcacccgg aagaaatcca
    13501 agactctctc ccgcttccac cgctggacga gttaggataa ttcgcttgac ttgcccacgt
    13561 ttaagggcag tcactgccaa ggtcactgca aggaaggtct tccctgtacc tgctggccca
    13621 attccaaagg tcacatcatg ctgtttgaca ctgtccacat aaagcttttg ccctagggtt
    13681 ttgacacgga taggtttccc agtattatct ttgataattt cttcttcgta aagggcgaca
    13741 aacttgtcaa tttcatcatt tttgaccatg ctaatcgcag tgactacatc tggcgtacca
    13801 acggtcatcc cacgatttac caagaccatc aaagcctgaa taacttgacg ggcttcctca
    13861 caggcagact cttctcccaa aacctggaca atctccgtac gagcatgaat cacaacatca
    13921 agctcttctt ccatcaaacg aagatggcgt tcattggaac caaaaagatg aaacaggtca
    13981 tctggatgac tcagttgaat gtctattgaa tgttccttca aataaagaac ctctctaatc
    14041 cttttatttc tttttattat agcagaggga tggagaaatt actagcccaa acccaatgaa
    14101 taaatgctag tgttctagat attcctgcca aatgctgtca aaatctccta ggttaaaaga
    14161 gaaactggca tgctcctcca aaaagcgact gacctcatca aaatcatctg tatgttttgg
    14221 aaaagctgcc tcttcaaaag cgaggtctgc caaaattgct ttgggactgt tacttttagg
    14281 attgcgctcg gtcatgagcc aagtgtaaaa tgattttctc ataagcctcc ctaaatcaac
    14341 tctgtcccaa actggtcctg cttgatttta ccagccttca taagaccacc taaagctttc
    14401 ttgaactgac ctttagaaat gccaaaggtt gccttgatgt cgtctggaga tgacttatca
    14461 tttaaggtca tgaaaccgcc attactttcc aaataagtca aaatcatctg agcatcgttt
    14521 tccaacattt caaaggagcg tggtttgagg gagaggttca gagtgcggtc cacttcacgg
    14581 aaaccaataa cgcgcgcatc taatacttgc cccaaacgtg gctctgcgta acgctcgcta
    14641 ggatgaataa aaccaagcat attattttct ggtaggtaaa caaaagttcc tgacagcttg
    14701 agacggtaaa caatggctgg ccagttttgg ttctgcatgt tgttgtaggc aggacgagca
    14761 agacgttgga agtcttcttg ataagccaag aggccccaga tacggtcttt cttatccact
    14821 tcaagacgga tgtagagttg gtcgcccttc ttaggccaga gttccttgag ctcagggaga
    14881 atatcgagtg acacaacgat ttccttgtca ggaaggcctg tatccacaaa gacacccaaa
    14941 tccttacgaa cctctgtgac acgtccccaa ccaaattggt cctgagtggc agtcacttct
    15001 aaggttgtca ggcggagttt ttgcttcata tccgtgtatg caaaaccttt gaccgtatcc
    15061 cctactgtat gttgaccttc ttccttagca agagcatagg tttgaccatc cttttgcaca
    15121 aagtaaaaac ggtcattttc atcgatgatc agtccaacga taaaacttgc aagatttgta
    15181 ttcatatttc cttctttcga ataaaactca gccagcaatg ccaactgagt ttttctgttt
    15241 atttttagac ttccaaaagt tctttctctt tgttagcagt catgtcgtcg atgtgtttaa
    15301 cagcatcgtc tgttactttt tgaatatctt tttcaagagt cttcaattcg tcttcagtga
    15361 tttcttttgc tttttcttgt ttcttagctt cgtccatagc atcgcgacgg atattgcgga
    15421 cagccacttt agcattttcg ccgaccttct tcacttcttt agcaaggtca cgacgagttt
    15481 cttctgtaag agctgggata accaagcgaa tcacagaacc gtcattagcc ggtgtgatac
    15541 caagatcaga agcgttcaag gcacgttcga tgtctttcaa tgaagacttg tcaaatggtg
    15601 ttaccaacaa aacacgcgct tctggaatcg taattgaagc gatttggtta agaggagttt
    15661 cgactccata gtattctaca tgtacacggt caagcaagct tgcattggca cgaccagcac
    15721 ggataccacc aaattcacga gcaagtgatt ggtgagattg ggtcattctc tctttagctt
    15781 tttcaataat tacgttagcc atattctttc ttattccttt tcttcgatat tatttgaaac
    15841 tgttgttccg atattttcac caaatacgac acgtttgatg ttgcctgatt ggttcatgtt
    15901 gaagacaacc aagtcaatgt cgttgtccat tgagagggtt gaggctgttg agtccatgat
    15961 acgaagacct ttgttgataa catcacggtg ggtcaattct tcaaacttaa cggctgtctt
    16021 gtccttctta ggatcggcat tgtacacacc atcgacgcca tttttagcca tgaggatggc
    16081 atctgcttcg atttcagctg cacgaagggc cgctgttgta tctgtcgaga agtatggtga
    16141 accaattcca gcaccaaaga taacgatacg gcctttttca aggtgacgaa gggcacgtcc
    16201 acggacataa ggctctgcca cttgttgcat agcaatagct gtttgtacac gcgtatcaac
    16261 cccaacttgt tgcaatgaat ctgccatcac aagagcattc ataacagtcc caagcattcc
    16321 agtgtaatct gcctgaacac ggtccatacc tgcttctgct gcaggttctc cacgccagag
    16381 atttcctcca ccgataacaa gggcaatttc gatacctaag ctatgaactt cttgaatctc
    16441 ttttgcgatt gtttgaactg tttggatatc aatccctacg ccacgttcac cggcaagggc
    16501 ttcacctgat aacttgatta aaatacgttt atacttggga ttcgccattt tcactctcct
    16561 tctttcatcc tacctatttt atcacaattt ctaagatttt tatagtatca tgaacaattc
    16621 tttcaaaaaa attagacagt caaaaattcc tctaagtcgg caagggcacg ctctgcaatt
    16681 ttttcataac gagccttctt atcacggata cgctcgcctt ccaactcctt gatgatccca
    16741 aaattgacat tcattggttg gaaatgtttg ctgtcggcat gggtaatgta atgagctaag
    16801 cttccaatcg ctgtcgtctc ggggaaaata acctcgcttt cttccttgaa gagacgagct
    16861 gcgttaattc ccgcaactaa gcccgaagcc gccgactcaa catagccttc cacccccgtc
    16921 atctgaccag caaagaagag atttggttgt ttcttggaac ggtaagtctg ctcaagaaga
    16981 tttggtgaat ccatgtaaga attgcgatgc atgacaccat aacggacaaa ctccgcattt
    17041 tcaagacccg gaatcatttg gaagacacgc ttttgttctc cccatttgag gtgggtctgg
    17101 aaaccaacaa tattgtatag gctaccagct gcattatcct gacgaagttg cacaaccgca
    17161 taaggtgttt taaattctcc atcacgaggt cctgtgtagt cgtccggata ctcaagaccg
    17221 actggcttca tagggccata aagcatagtt ttaatgccac gtttggccat aacttcgatt
    17281 ggcatacatc cttcaaagta cttttctttt tcaaaagaat tgagcggtgc ttcttccgca
    17341 ttgaccaagg cttcatggaa atccataaac tcttgcttgg tcattggagc attgagatag
    17401 gctgcttctc ccttatcata acgagatttg agatagacct tactcatatc gatagtgttg
    17461 acatcgataa taggcgctgc tgcatcgtag aaatagaagc catcgccatt attaagggca
    17521 tgaatctttt cagccagggc atcgctagtc aagggaccag tcgccacaac tgtaataaca
    17581 tctgttggca attctgtaat ttcatcacgc accacttcaa tcaaggggtg gttgaccact
    17641 ttttcggtca ccatttgaga gaaaccatca cgatccaccg caagggctcc accggcagga
    17701 acacgtgtag cctcagcaga ttccaagata acagaaccca agcgacgcat ttcttccttg
    17761 agaagaccaa ctgcatttgt caaagcatcc ccacgcaaag aattggaaca aaccaactca
    17821 gcaaaattgt ctgttttatg ctggggtgta gacttgacac cacgcatttc atatagttta
    17881 actggaatac cacgctctgc gatttggtaa gctgcttcag aacctgccaa accagcaccg
    17941 ataacattga tataagattg agacacgaca ctaatacctc tttgggagtg tgaagttaag
    18001 attcacattg aaaaagccaa tcagacttac aagctttcga gtttcttggc tcaggctgaa
    18061 aaagtccaca ggactttttc actcccacaa atctttctat tttttcttct actagtataa
    18121 caaaaaaagg gaagaaggca aacttccctg tttagtcatt ttcttgatgt aaagagatag
    18181 tgagtattcc agttaagaat caattatatg ctactctata aaatcttttc cacataacgg
    18241 atcgataggg actgttattc tatctcttgc tataaccgta ttatctaaaa cagcataaca
    18301 ttcaacatag tgatctcctt taaactgtga atcttcgtga tattttattt tacctgaaaa
    18361 aatagcacca cgctcacaat ttcttctaat agcctcagct tcaatatttc ttactttcca
    18421 atagacttcc tgcgaaa
//
LOCUS       DAVMCG010000041        18254 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVMCG010000041 DAVMCG010000000
VERSION     DAVMCG010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.042"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            359..1405
                     /gene="pheS"
                     /locus_tag="VYP66_001670"
     CDS             359..1405
                     /gene="pheS"
                     /locus_tag="VYP66_001670"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1851186.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1405..1914
                     /locus_tag="VYP66_001671"
     CDS             1405..1914
                     /locus_tag="VYP66_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851187.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETLAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1991..4396
                     /locus_tag="VYP66_001672"
     CDS             1991..4396
                     /locus_tag="VYP66_001672"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1851188.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQDTEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPLVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4464..5465)
                     /locus_tag="VYP66_001673"
     CDS             complement(4464..5465)
                     /locus_tag="VYP66_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1851189.1"
                     /translation="MIKTFLSALSVILFSIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5621..6068
                     /locus_tag="VYP66_001674"
                     /pseudo
     CDS             5621..6068
                     /locus_tag="VYP66_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6194..6451
                     /locus_tag="VYP66_001675"
     CDS             6194..6451
                     /locus_tag="VYP66_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1851190.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVRLEQ"
     gene            6721..8970
                     /gene="metE"
                     /locus_tag="VYP66_001676"
     CDS             6721..8970
                     /gene="metE"
                     /locus_tag="VYP66_001676"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1851191.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLDTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9034..9900
                     /gene="metF"
                     /locus_tag="VYP66_001677"
     CDS             9034..9900
                     /gene="metF"
                     /locus_tag="VYP66_001677"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1851192.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10585..12798
                     /gene="pnp"
                     /locus_tag="VYP66_001678"
     CDS             10585..12798
                     /gene="pnp"
                     /locus_tag="VYP66_001678"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1851193.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12814..13431
                     /gene="cysE"
                     /locus_tag="VYP66_001679"
     CDS             12814..13431
                     /gene="cysE"
                     /locus_tag="VYP66_001679"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1851194.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13443..14327
                     /locus_tag="VYP66_001680"
     CDS             13443..14327
                     /locus_tag="VYP66_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851195.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14409..15752
                     /locus_tag="VYP66_001681"
     CDS             14409..15752
                     /locus_tag="VYP66_001681"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1851196.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETVRKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            15745..16131
                     /locus_tag="VYP66_001682"
     CDS             15745..16131
                     /locus_tag="VYP66_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1851197.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16135..17019
                     /locus_tag="VYP66_001683"
     CDS             16135..17019
                     /locus_tag="VYP66_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1851198.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17261..17860
                     /locus_tag="VYP66_001684"
     CDS             17261..17860
                     /locus_tag="VYP66_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851199.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYTTIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYAPLNDVTKYAR"
     gene            18003..18173
                     /locus_tag="VYP66_001685"
                     /pseudo
     CDS             18003..18173
                     /locus_tag="VYP66_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5504 a         3523 c         4140 g         5087 t
ORIGIN      
        1 taattttact ttcccaatcg atttgttttc atcttatttc aatccgctat aaagttagat
       61 aagaataagc taacaagcag aagtaagata ggtcttgcaa gaatggtaaa aatctgataa
      121 actaagtagt aattgaatag gaatctgaaa gactagtagc ccaagggaag tatatcaggg
      181 aggagagccg tgactgcaag ctctctatat gaaagctggg tgaattcact tgcgcatgga
      241 tttagaaatg aaggtctgac ttgtcagatg aaaacggatg gtaccgcgtg tcaacgctcc
      301 gagtggagtt tttggcatgt ggttttcttt ttatctacga gagactgatg gaggaaatat
      361 gtcaactatt gaagaacaat taaaagcgct tcgcgaagaa acgctggcta gcttgaagca
      421 gattactgct ggaaatgaaa aagagatgca agatttgcgt gtctctgtcc ttggtaaaaa
      481 gggttcgctc actgaaatcc tcaaagggat gaaagatgtt tctgctgaga tgcgtccaat
      541 catcgggaaa cacgtcaatg aagctcgtga tgtcttgact gctgcttttg aagaaacagc
      601 taagctcttg gaagaaaaga aagtcgcggc tcaactggct agcgagagta tcgatgtgac
      661 gcttccaggt cgtccagttg cgactggtca ccgtcacgtt ttgacacaaa ccagtgaaga
      721 aatcgaagat atcttcatcg gtatgggtta tcaagtcgtg gatggttttg aagtggagca
      781 agactactat aactttgaac gtatgaacct tccaaaagac cacccagctc gtgatatgca
      841 ggatactttc tatatcactg aagaaatctt gctccgtacc cacacgtctc cagttcaggc
      901 gcgtgctatg gatgcccatg atttttctaa aggtcctttg aagatgatct cgccagggcg
      961 tgtcttccgt cgcgatacgg acgatgcgac ccacagtcac caattccacc aaatcgaagg
     1021 cttggtagtt gggaaaaata tctctatggc tgatcttcaa ggaacgcttc agttgattgt
     1081 ccaaaaaatg tttggtgaag agcgtcaaat tcgtttgcgt ccatcttact tcccattcac
     1141 agagccatct gttgaggtgg atgtttcttg cttcaagtgt ggtggagaag gctgtaatgt
     1201 atgtaagaaa acaggttgga tcgaaattat gggggccggt atggttcacc cacgtgtcct
     1261 tgaaatgagt ggtatcgatg cgactgtata ctctggcttt gcctttggtc ttggacaaga
     1321 gcgtgtagct atgctccgtt atggaatcaa cgatatccgt ggattctacc aaggagatgt
     1381 ccgcttctca gaacagttta aataatgatt agaaaagtag aaatggcaga tgttgaggtg
     1441 ttggctaaaa ttgccaaaca agcctttcgt gaaacccttg cgtatgataa tacggaagag
     1501 cagttacagg aatactttga agaggcttat agtctgaaaa ctttgtcaac tgagttggga
     1561 aatcctgact ctgaaaccta tttcattatg catgaggagg agatagctgg ttttctcaaa
     1621 gtcaactggg gaagtgctca aactgagaga gaattagagg acgcttttga aattcaacgc
     1681 ctctatgtgc tacaaaaatt ccaaggattt ggactaggta agcaactgtt tgaattcgca
     1741 cttgaacttg ctacaaaaaa tagtttttct tgggcttggc taggtgtttg ggagcataat
     1801 acaaaagctc aagcctttta taaccgatat ggttttgaaa aatttagcca acatcatttt
     1861 atggttggtc aaaaagtaga tacggattgg ttactgagaa agaaattaag gtaagaagag
     1921 aattcttcta ttgaaatgat aggaaaggaa aagaaccagt gtggcaatgg tcattctgga
     1981 gaactaaatt atgcttgtat cttataaatg gttaaaagaa ttggtggaca ttgatgtgcc
     2041 atcacaagag ttggctgaaa aaatgtcaac tacagggatc gaggtagagg gtgtcgaatc
     2101 accagctgct ggtctctcaa aaattgtcgt cggtgaggtc ttgtcttgcg aagatgtgcc
     2161 agagactcac ctccatgttt gtcagattaa cgttggcgaa gaagaagagc gtcagatcgt
     2221 ttgtggtgcc ccaaatgtgc gtgctgggat caaggtcatg gtggctcttc caggagctcg
     2281 tatcgctgat aactacaaaa tcaaaaaagg aaaaatccgt ggtttggagt cacttggaat
     2341 gatctgttca cttggtgaat tgggaatttc tgactcagtt gtgcctaagg aattcgcaga
     2401 tggcatccaa atcttgcctg aagatgccgt gccaggtgag gaagtctttt cttacctaga
     2461 cttggatgat gaaatcatcg aactttccat cacaccaaac cgtgcagatg ccctttctat
     2521 gtgtggagtg gctcacgaag tggcagccat ctatgacaag gcagtcaact ttaaaaaatt
     2581 tactctaaca gaaactaatg aagctgcggc agatgccctt tctgtcagca ttgagacaga
     2641 caaggcgcct tactatgcag ctcgtatctt ggacaatgtg actatcgcac caagtccaca
     2701 atggttgcaa aaccttctca tgaacgaagg catccgtccc atcaataacg ttgtagacgt
     2761 gacaaactac atcctgctct actttggtca acctatgcat gcttttgact tggacacatt
     2821 tgaagggact gacatccgtg ttcgtgaagc gcgtgatggt gaaaaattag tgaccctgga
     2881 cggtgaagag cgagacttgg ctgagacaga cctcgtgatt acagttgctg acaaaccagt
     2941 agcccttgcc ggtgttatgg gtggtcagga tacagaaatt tctgaaaaat ctagtcgtgt
     3001 tatccttgaa gctgctgttt ttaatggcaa atctatccgt aagacaagtg gtcgcctgaa
     3061 ccttcgttct gagtcatctt ctcgctttga aaaaggaatt aatgtggcaa cagttaatga
     3121 agcccttgat gcggcagcta gcatgattgc agagcttgca ggcgcgacgg tgcgtaaggg
     3181 tatcgtttca gcgggtgagc ttgatacctc tgatgtggaa gtttcttcaa cccttgctga
     3241 tgttaatcgt gtcctcggaa ctgagctgtc ttatgctgat gtagaagacg tcttccgtcg
     3301 tcttggcttt ggtctttctg gaaatgcaga cagctttaca gtcagcgtac cacgtcgtcg
     3361 ttgggatatc acaatcgaag ctgatctctt tgaagaaatc gctcgtatct atggatatga
     3421 ccgcttgcca accagccttc caaaagacga tggtacagct ggtgaattga ctgtgacaca
     3481 aaaactccgc cgtcaagttc gtaccattgc tgaaggagca ggtttgacag aaatcatcac
     3541 ctatgctctg acaactcctg aaaaagcagt tgagttcaca gctcaaccaa gtaaccttac
     3601 tgaactcatg tggccaatga ctgtggatcg ttcagtcctc cgtcaaaata tgatttcagg
     3661 gatccttgat accgttgcct acaacgtggc tcgtaagaac aaaaacttgg ccctttacga
     3721 gattggaaaa gtatttgaac aaacaggtaa tccaaaagaa gaacttccaa atgagatcaa
     3781 cagctttgcc tttgccttga caggcttggt tgctgaaaaa gatttccaaa cagcagcagt
     3841 tccagttgat ttcttctatg ctaaaggaat cctagaagcg ctctttactc gcttgggact
     3901 agaagtgacc tatacagcaa cagctgagat tgccagcctt cacccaggac gtacagcagt
     3961 catttcactc ggtgaccaag ttcttggttt tcttggccaa gtgcatccag tcactgctaa
     4021 ggcctacgat attccagaaa cgtatgtggc tgagcttaac ctttcagcta tcgaagctgc
     4081 gcttcagcca gcgactccac ttgtagaaat caccaaattc ccggcagtca gccgtgacgt
     4141 tgcccttctc ctcaaggcag aagtgactca tcaagaagtt gtagatgcta tccaagctgc
     4201 cggcgtgaaa cgtttgacag atatcaaact ctttgacgtc ttctcaggtg aaaaactggg
     4261 acttggtatg aagtcaatgg cttatagctt gaccttccaa aatccagaag acagcttaac
     4321 ggacgaagaa gtcgcacgct acatggaaaa aatccaagcg tctctcgaag aaaaagtcaa
     4381 tgcagaagtg cgttaaacga tagtaggata caaattcccc ctctagttta tgaacactag
     4441 aggggtgatt ttatataaaa taattaaaat gtgatttctg taaaaataca tctatgatca
     4501 gagttttgaa aacttacaat gtctaaatct ttaacatagt agtggttttt aggcaataaa
     4561 atatgatcta ttgttgcatt aaaaagtttt ggactttggc tattccaagt tcctctttca
     4621 aaaggtggaa gtgcattcaa tgcgtcccta tgagagctta tttttgcaag tgctccatga
     4681 cgcatagttg cattaaaatc acctgcaata atagcctttg gatattttga agccaattga
     4741 ttatgaatga tgtttaagtc ttgcttccag atttccatta aacctggcag aggaggagca
     4801 gtatgcaagg caatgatatc tggtatattt tgttttctcg aatgtaatac aattgtcccg
     4861 aaccgtgttg tatgaaaagt tttagcttct gtatagaaac cataactttt cttgacaatc
     4921 acagtcacag gagctattcc actattggta ggtggagaag tgaaaatatc atagttggcc
     4981 atagaaagtc caacttgatg aaacaatagt ttgattctct ggttttcttg ctcacctctg
     5041 atattggtag ctagttcagg gaatatagcc atatcggcat caaaatggct aaaaattcgc
     5101 tcaatatgtt gtgcttctat ttgattagcg acgttccaag ttactaattt taaggtttta
     5161 gtcttatttg atgcagaaga aagggtttta tctgttccga ataatagtaa tatgagcgat
     5221 agtaagagca aaatgccaga gtaaaaccgt atttgtttat ttttcttgta aaaagatagg
     5281 gaaaaaaata cgaaacttaa aatagaagcc atagttgcag tagctaaggg gaaggcataa
     5341 atctgtgcca agataggtct ggtagatagc caaatattaa gattagaaga tgggaaaaaa
     5401 gaataagtta tgatagggat agaaaagaga atgaccgaaa gggcagagag aaatgtttta
     5461 atcattgtgt gagtacctca atttgcaatg gttgctcgga gctaatgtga ctttgtgact
     5521 ttacttgatt gatattcttt ttcttgtctt ccttatagat taagtacaac ccaagtaaaa
     5581 aaagtccaat ttaagattga aatgattaaa aggcacagag atgcaagaca attatactac
     5641 aaaaggtaaa catttgacaa tcgatagccg tcgcttaatc gaaagatgga aaaaagaagg
     5701 aaaatcaaat agagaagttg cctctctact tggaaaagct cctcaaacta tccacactga
     5761 aatcaagcgt gggacagtcc gaaaatgtct tggaaaaggg cgcttcaaag aggtttattc
     5821 tgccgactac gctcaacagt cttatgaaaa caatcgcaag cgctcggtca agaaatcaag
     5881 cttgaccaag gaactaaagg aaaagattct ccactataca taaccaaaaa ttttcgcctg
     5941 aaatgatggt gatggctaaa ggggttaacg tgggaatttc aaccatttac tattggattc
     6001 atcgtggaaa attggggtta agcaagcagg atctgcttta tcctagaaaa ggaaaatcgc
     6061 ttaagaaata ggctagcacc aactttaaac ccgctggtca atctatcgaa tcataattcg
     6121 ctcatttttt taaaaataca tagacgtaaa agaaagaggg ttaagtgatg aagaatagtg
     6181 ctattgggag taattggaag gatgtccatc tgagctcttt agcaaggagg aaatccttga
     6241 aagtgatatg cgagtggcta tcatgagcga gttgattgag gctaggtatg aacaaggaat
     6301 cagtcagaaa aagctggaag aagtcagtgg aataagccag cctgtcatag ctaggatgga
     6361 gacaggaaag actagtcctc agttggatac agtcttaaaa gtcctagcca gtttaggaaa
     6421 gacactagca gtcgtccgac ttgaacagtg aaaaagttga ctagaatcag ttatagtctt
     6481 ttctaataac aagccatagt cacttataag aattactaat aacgcgtttg aaccgtctaa
     6541 ctgaaataaa gctataaaac aagctataca aaggatttga gacgtttgct tcaagtcttt
     6601 ttcttttgtc cgaaacagat atatagtttc aaactatatc aaaccctaat tttttacaat
     6661 tatacagacg ctttcttttc tgttaagata gtttcaacaa caaattttgg aggacacatc
     6721 atgtcaacta caatcatcgg tttccctcgt ttgggcgaat tccgtgaatt aaaatttaca
     6781 actgaaaaat actttagaaa agaaatctca gaagaagaac ttttagcagc agcaaaagac
     6841 ttgcgtgcta aacactggaa cattgtcaaa gaaaaaggca tcactgaaat tccatcaaat
     6901 gacttttctc actatgataa cttcctagat gcggctttcc ttttcaacgt ggtgcctgca
     6961 tccgttcaaa acttggactt gtctgacctt gagcgctact tcgctttggg acgtggttac
     7021 cagggagaaa aaggggacgt tcgcgccctt ccaatgaaga aatggttcaa cactaactac
     7081 cactacatcg ttcctaaatt tgaaaaagac actcaagtaa aattggctgg tcacaagatt
     7141 ttcgatgagt tccaagaagc aaaagaactt ggattggaca ctcgtcctgt tcttgtaggt
     7201 ccattcactt tccttcaatt gtcagacttt gaagaaggcg tgaaagcaga cgacttcgta
     7261 gatagctttg tggctgctta ccaagaagtt tttgctaaat tggctgacct tggtgcgact
     7321 cgcatccaat tggatgaagc ggctcttgta aaagacttga cagctgaaga aaaagctctc
     7381 ttcttgaacc tttacaacaa actcttggct gacaaaaaag gtcttgaagt cttgtttcaa
     7441 acttatttcg gtgatgttcg tgacgtatac gctgaccttg taaacttgcc agtagatgct
     7501 atcggtcttg actttgttga aggtaagaaa actcttgaac tcgttaaagg tggcttccca
     7561 gctgacaaga ctctctatgc aggtattgtc aatggtaaaa acatctggcg caacaactac
     7621 gaaaagagct tggctgttct tgagcaaatc ccagctgaaa acatcgtttt gacaagctct
     7681 tgctcacttc ttcatgtgcc atttacaact gctaatgaag aatttgaacc agcactcttg
     7741 aaccactttg cctttgcagt tgaaaaattg gatgaaatcc gtgacttgga tgctatccgc
     7801 aatggtcaag gttcagaagc tcttgcagcc aacaaagaac tctttgcgac tgagcgtgtt
     7861 ggtgaaaatg ctgaacttcg tgcgcgtatc gctggcttga cagacgcaga ctacactcgt
     7921 ttgccagcct ttgcagaacg tgaagctatc caagaagaag ctttcaaact tccagctctt
     7981 ccaacaacaa cgattggttc attccctcaa acaaaagaag ttcgtgccaa acgtttggct
     8041 taccgtaaag gtgaattgtc tcaaaaagag tacgacgctt tccttgctga aacgattgac
     8101 gaatggatca agtggcaaga agatattgac tttgatgtcc ttgttcacgg tgaatttgag
     8161 cgtaatgaca tggttgagta cttcggtcaa aacttgtcag gatacctctt ctctaaaaat
     8221 ggatgggtac aatcatacgg tatgcgtggg gtaaaaccac caatcatctg gggtgatgtc
     8281 actcgtctta accctatcac tgttaaatgg tctagctatg cacaaagtcg tacaaacaaa
     8341 cctgttaaag gtatgttgac tggacctgtt accatcctta actggtcatt cccacgtgaa
     8401 gacatctcta tcaaggattc aactctccaa atcgcccttg ctatcaagga tgaagtactt
     8461 gaccttgaag ctgctggtgt gaaaatcatc caaatcgacg aggctgctct tcgtgaaaaa
     8521 ttgccactcc gccgtagcga ctggtacgaa gactaccttg actgggctat tcctgccttc
     8581 cgcttggtac actcaacagt agcgccagac acacaaatcc acactcacat gtgttactca
     8641 gaatttacag atatcatccc agctatcgat aacatggatg cagacgttat ttcctttgaa
     8701 gctagccgtt caaaccttga aatcttggac gaactcaaag cgaaaaactt ccaaacagaa
     8761 gtgggacctg gggtttacga tatccactca cctcgtgtac caaatgaagg cgaaatcgac
     8821 aacacaatcg aagccatcct tgctaaagtg ccaagcaaga aagtttggat caaccctgac
     8881 tgtggtttga aaacacgtgg tatcccagaa acaaaagaaa gcttgatccg ccttgttgaa
     8941 gcagctaaag ctgcgcgtga gaaattgtaa gattggattt ctctccatac agtggttgtt
     9001 caaaaagaaa tcaactagaa aaggttatta catatgtcac gccaaacacc gtcactctca
     9061 tttgaagtgt tccctccaaa cccagccgtg ggtaatggta acattatttc agccttgcag
     9121 gatatgcagg agttggctcc ccattttatc agtgtaactg ccagcaataa taaatttaat
     9181 atcaaggaaa cgacggttcg tttggctgac tttatccaaa atgatttggc gattccgacc
     9241 attgcccact tgccagctat ttatctaact aaggacaagg ttgctgaaac tattgctgac
     9301 ttggacaaag ttggggtgca gaaaatcttg gctcttcgtg gggatattat tccagacgtg
     9361 gaaccacaaa aggatttccg ctatgcaacc gacttgattg agtttatcaa ggaacaaacc
     9421 cctcactttg atattattgg agcttgctat ccagaagggc atccagattc gccaaatcag
     9481 atttcagata ttcaaaatct taagaagaaa gtggatgcag gctgttcgag cctcgtaact
     9541 cagctcttct ttgacaatga gcgcttctat gattttcagg acaagtgcat cttggctggg
     9601 attgatgttc ccattcatgc aggaattatg ccaattctga atcgaaatca ggctctccga
     9661 ctcttgaaga cttgtgagaa tatccatctt ccacgcaaat ttaaagccat cttagacaag
     9721 tatgagcatg accctgagtc gctcagagca gcaggacttg cctatgcagt ggaccaaatc
     9781 gtggacttgg taactcagga tgttgccggt gtgcatctct atacgatgaa taatgctgat
     9841 acagcaaaat acatccatca agcaacccat gccttgttta atcaccagtc tctaggataa
     9901 taaaagcaaa ccattcttct caggtgaggg gaatggttcc tttttaatgg taaagacctc
     9961 actttttaag aaaaatatga taaaataaat tctgtacgta cttgatacaa agatgaaggt
    10021 attaaataat acaatgcatt taaactgtaa gatttaacga cacgagtgag tcaaatcgat
    10081 gttatttgac gagagagtta gtaaagcatt tagctaatcg cccgatagcg attagcgtga
    10141 aagctttaga tactttagta ttaaaccttt ctaatgatgt atcttgaaaa ctgaacttgc
    10201 ctacaactct gtggaaaaag ataaatctcc ctaggagcag tcgctccgtc gttcgatttc
    10261 ctattttcct ttgagttgct tgacggcttg gtatcttgat gacttgaatt ttggtctcat
    10321 ttcttaggaa aaaagataag cttcctagca ctcgtcgagt gcgacgtcac cttcctattt
    10381 ttctacagaa atgttcggca agccgaaccg tccaaaatat cttgtgtaat tgaacacggc
    10441 cgaaaagctg tgtaaaaaag ataaactgtc ttgtcttcat cgaagacttc gtcagtttcc
    10501 tatttttact ttgcttttga cgtccttggt atcttgatct ttgtaggcaa ggcgtataat
    10561 ttcatcaatc caaaggggat taaaatggca aaacaagtgt ttcaaacgac ttttgcgggt
    10621 cgtgagttaa ttgtagaaac tggtcaggtt gctaagcaag caaatggctc tgttgtcgta
    10681 cgttacggtg agtcaactgt cttgactgct gccgttatgt ctaagaaaat ggcaactggg
    10741 gatttcttcc cactccaagt caactacgaa gaaaaaatgt atgcggctgg gaagtttcct
    10801 ggtggcttta tgaaacgtga aggacgtcct tcaacagatg cgaccttgac agcgcgtttg
    10861 attgaccgtc cgattcgtcc tatgtttgcg gaaggtttcc gtaatgaagt ccaagtcatc
    10921 aatacagtgc tttcttatga tgaaaatgca tctgcaccaa tggctgctat gtttggttca
    10981 tctttggcac tgtctatttc agatattcca tttgacggac caattgctgg ggtacaagtg
    11041 ggatatgtag atggccaaat catcatcaac ccaagtcaag aacaagcaga gcaatctctt
    11101 cttgaattga cagtagctgg aaccaagcac gctatcaaca tggtagagtc tggtgccaaa
    11161 gaattgtcag aagaaatcat gttggaagcg cttcttaaag ggcacgaagc tgtcaaagaa
    11221 ttgattgcct tccaagaaga aatcgttgct gctgtcggta aagaaaaagc agaagtggaa
    11281 ttgcttcacg tggatgctga attgcaagct gaaatcattg cagcctacaa cagtgacctc
    11341 caaaaggcag ttcaagtaga agagaaattg gcccgtgaag ctgcaactca agcagtgaaa
    11401 gaccaagtga ctgccgttta cgaagaaaaa tatgcgaacc acgaagaatt tgaccgtatt
    11461 atgcgtgatg tggctgaaat cttggaacaa atggaacacg cagaagtgcg acgtttaatt
    11521 acagaagaca aggtgcgtcc tgatggtcgt aaggtcgatg aaatccgtcc tttggatgcg
    11581 gttgttgact tccttcctcg tgtacatggt tcaggtctct ttactcgtgg gcaaactcaa
    11641 gctctttcag tcttgacctt ggctccgatg ggagaaactc aaatcattga tggtttggat
    11701 ccagagtaca agaaacgctt tatgcaccac tataacttcc ctcaatattc tgtaggggaa
    11761 acaggtcgtt acggtgcgcc aggtcgtcgt gaaatcggtc acggtgctct tggtgagcgt
    11821 gctcttgctc aagtcttgcc aagcttggaa gaattcccat acgctatccg tctagtagca
    11881 gaagttttgg aatcaaacgg ttcttcatct caagcttcta tctgtgcggg aactcttgcc
    11941 cttatggctg gtggtgtgcc aatcaaggcg ccagtagctg gtattgctat gggacttatc
    12001 tcagatggaa ataactacac agtattgaca gatatccaag gtttggaaga tcactttgga
    12061 gatatggact tcaaggttgc aggtactcgt gatgggatta cagcccttca aatggatatc
    12121 aagattcaag ggattactgc agaaatcttg acggaggctc ttgctcaagc caagaaagcg
    12181 cgttttgaaa tccttgatgt cattgaagca accattccag aagttcgtcc agaattggct
    12241 ccaactgctc cgaaaattga tacgatcaag attgatgtgg acaagattaa gattgtcatc
    12301 ggtaagggtg gagaaaccat cgacaagatt atcgctgaaa caggtgttaa gattgatata
    12361 gacgaagaag gaaatgtgtc tatctactct agtgaccaag atgctattaa ccgtgccaaa
    12421 gaaattattg ctggtttggt tcgtgaagcc aaagtggatg aagtttaccg tgctaaagtc
    12481 gttcgtatcg agaaatttgg tgcctttgtt aacctctttg ataagacaga tgcccttgtt
    12541 catatctctg agatggcttg gactcgtacc aatcgtgtag aggatttggt agaaatcggg
    12601 gatgaagttg atgttaaggt tatcaagatt gatgaaaaag gccgtatcga tgcctctatg
    12661 aaggctcttc tacctcgtcc gccaaaacct gagcatgatg aaaaaggtga aaagtctgag
    12721 cgccctcacc gcccacgtca tcacaaggat cacaaaccta agaaagaatt tacagaaaca
    12781 ccaaaagatt cagagtaaga aaaggagaaa tgtatggggt ggtggcgcga aaccattgat
    12841 atcgtaaaag aaaatgatcc agcggcccgc accactttgg aggttttgct gacttatcca
    12901 ggtgtcaagg ccttggcggc ccaccgtctc tcgcattttc tctggaagca cggcttcaaa
    12961 ctcttagctc gtatgtacag tcagttttgg cgcttttgga ctcagattga gattcatcca
    13021 ggagcccaga ttgattcagg tgtctttatt gaccatggtt ctggtctggt gattggagag
    13081 acagcgattg ttgaaaaagg cgttcttctc tatcacggag tgactcttgg gggaacaggg
    13141 aaagactgtg gcaaacgcca tccgactgta cgaaagggag ccctcatatc agcccatgcc
    13201 caagttatcg gacctgtgga aattggtgaa aatgccaagg tcggtgctgc agcagttgtc
    13261 gtagcagatg tacctagtga tgtgacggtt gtcggtattc cggccaagat tgtccgtctt
    13321 catggtaaga aagatgagcc tgtcattcac gaagtcgaag aaaaacgaga gtattatgtc
    13381 aataaactcg agcaggctaa agatgccagt cacagatcgt ctggtttgta gaggatacct
    13441 atatgattca agtaagaaac aagttaagcc aagaggagct atctgaggcg aaaaaagtaa
    13501 ttaactgttg ccaaaactat gacggtacct atcgcgatcc ctatctctct aacatgctta
    13561 attttgaccc aaacatgccc gcctttttcc tttattatga aaaaggcgaa cttgttggtt
    13621 tattaactgt ctatgcagat gaccaagatg tagaagtgac gatactggtt catccaggtc
    13681 atcgccgtca ggggattgcg cgtgcattgt ttactagttt tgagagagaa acagcttctt
    13741 tccccattcg atcagtcact tttcagacag aacgtatttt tttagagaat catcctgact
    13801 ttgccagtaa ctggggacta atcgaggatg aagagacaga aacttggtta ggtaaggata
    13861 gaagacctta tccgttagca aatgtttccc atcttgaagt tttgttagca gatagttcgt
    13921 atcaggatca aattagtcaa ttaaaatttc aggcattttc agaggaacat gaatcgagag
    13981 aagttgtgga tagatatgtc gctgaagctc tgaaggatcc agaaagtcgc ttatatattt
    14041 tgttaaaaga cggtcaggtt attgggactt gcacggttga tttatcgagc gatacgaatt
    14101 acttctacgg tttagcaata tcagaacctg aacgtggaaa aggctatgga agctacttag
    14161 caaaatccct tgtcaaccaa ctaattgagc aaaatgataa ggaatttcag attgcagtgg
    14221 aagatagcaa tgtaggtgcc aaacgtttgt atgaaaaaat tggctttgtc aaacagactc
    14281 aggtggttta tctgaatgag aaaggagcaa gggattccga agtgtagaga tattcggact
    14341 gaaatttact tgaactttta gtgatgaaac taattgttct tggatttcag ctttcctgat
    14401 tatgatttat gattaaaatc tatgacacca tgtctcgtga tttgcgagaa tttgtcccga
    14461 ttgaggacgg caagatcaag atgtatgttt gtgggccaac ggtgtacaac tatatccacg
    14521 tgggaaacgc ccgttcgacg gtagcttttg atacgattcg tcgctatttt gagtaccgtg
    14581 ggtataaggt tgcctatatt tccaatttta cagatgtgga tgataagatt atcaaccgtg
    14641 ccagggaaga aggtatcacg cctcaggagg ttgcggataa gtacatcgct gcctttcgtg
    14701 aggatgtgac ggccttaggc gtgaaacctg cgactcgcca tccgcgtgta gtggagttta
    14761 tggcagacat catccgtttt gtggaagact tgatcgagaa aggctttgcc tatgagagtc
    14821 aaggggatgt ctatttccgt gtagaaaaat cccacaacta tgccaaattg gctaataaaa
    14881 ccttggaaga tttggatcta ggtgcttcag gtcgtaccga tgaagaaacg gttcgtaagg
    14941 aaaatcctgt agattttgct ctatggaaat cttccaaacc aggtgagatt tcttgggata
    15001 gtccttgggg acctggacgt ccgggttggc acattgagtg ttcagtcatg tcgacagaga
    15061 ttttaggtga taccattgat atccacggtg gtggagctga cctagaattt ccgcaccaca
    15121 ccaatgaaat tgcccaatct gaagctaaaa caggcaaggc ttttgctaac tactggatgc
    15181 acaatggctt tgtcaatatc gacaatgtca aaatgtctaa gtccttgggt aacttcatta
    15241 cggtacacga tgcccttaaa actcttgatg ggcaagtact tcgtttcttc tttgcgaccc
    15301 agcactaccg taagcctatc aacttcacgg aaaaggcagt tcgcgatgcc gagaccaatc
    15361 tcaagtatct gaagaatact tacgaacaac catttacagg aaacgtggat gcccaagagt
    15421 tacaaaactt taaagataag tttgtagcag ctatggatga agattttaat gctgccaacg
    15481 gtatcacagt tgtctttgaa atgaccaaat ggatcaactc agggaactat gatgcaagtg
    15541 tcaagcaagc tcttgcagat atgttagaaa tttttggaat tgtctttgtt gaggaagttt
    15601 tggatgcaga gattgaagac ttgattcaaa aacgccaaga ggcgcgtgcc aatcgagact
    15661 ttgagacagc agaccaaatc cgtgaccaac tggctgctca aggcattaaa ctattggata
    15721 caaaagatgg agtgaggtgg acacgtgatt gatgtcaatc tcattaacgg gattgcgcta
    15781 gcctttgagg gagatgcggt gtattctatg tatattcgcc gccacctcat cctcaaaggt
    15841 atgaccaaac ccaataaact ccatcaagaa gcaaccaagt atgtgtcagc caaggctcag
    15901 gctcgcctga ttgctctcat gttggaggag caggtcctaa cggaaaaaga agaagaaatc
    15961 tacaaacgtg gccgcaatac caatagccac acaaaggcta aaaatgcaga tgtcgtgact
    16021 tatcgtatgt ccacgggatt tgaagcggtt atgggctatc tccatatgac tgagaatctg
    16081 gaacgtcttg agagtttggt ttcatggtgc atccaaaaag tggagggcta gaacatgagg
    16141 gaaaaagaac tacaagactg gtttcctgag gctcggattt cagaccaacc agtagagaaa
    16201 gagggctatc tcacgctccc tttagcttct cagcagtgga ttttgctgga ggaagctggg
    16261 ctcagcgagc gtgaaaagca gttggttgcc cttttgaccc agcaggagca ggctcgttcg
    16321 ctaaaccctt ggtattccta tctggttgaa ggcaagggac aggcaccgca agtttttaaa
    16381 aagattcagt tggtttattg ccatctttct tattttcagc aggaaaatct gacttcttgg
    16441 ctagatatga tgcggactct ttttccgaat tgtcagacag tgctacaggt cggagctcag
    16501 gattatgttt tcgtgcttca acaagacaaa tacacttctg taagagatat tttaagtgat
    16561 acgattgaag cggttgagta tgattttgga cttcgtcttt ctatcatgtt gggtcaggtt
    16621 tggtctcaga caggacatca agccctatca gacttaatca aagctgagcg ggatttgttc
    16681 aagacatggt ggcgtcaggg tcaccaaggt gttcatactt tttctcagct ctatctttgg
    16741 agtatgggag aaagactcgt ggacttgaag ccaattaaag aatgtctaca ccagatgatt
    16801 ttggatcaag atcagattca ggaaatcatt ctctctcttt gggaaaatag tgctgttctc
    16861 actaaaacag cccagcaact ctatctgcac cgcaattctc tccaatacaa gattgataaa
    16921 tgggaagagt tgacagggct tcagttgaaa gagttgaccg acctgacctt gtgttatcaa
    16981 ttgattttag gttctttgtc aactatagtt ggtttgtaaa gaagttaata tttggagaag
    17041 aggattgcca tcttctccat ttttatgtgc agagttatag tggcttgatg ctgggaaagt
    17101 acactgtgac tgataatact caatgaaaat caaagtacaa actaggaagc tagccgcagg
    17161 ctgtacttga gtacgtcaag gtgaagctga cgtggtttga agagattttc gaagagtata
    17221 aaacattcct agaagttgct ttgatttccc taatctattt atgcaaattt tatgttattt
    17281 tactataaca gttgttgcta agccaaataa tagtggggaa gttcatttag acgtaagcat
    17341 tgaagataat cagggaggta gtgggcataa tttcagttct gtttcaagta gctcacaaac
    17401 agctaaatat gaagaaactg gttataataa caattcatca ttatatacaa cgattgataa
    17461 aacgtctgat gcaacagctc ttttgaaatt aaagttgaat aatgttgata atcaacctgc
    17521 tactgaagtt cctagttcag gaattactgt aaaattaaat gctaaagata atgctggaaa
    17581 ctggacaagt gcttcgaata aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac
    17641 atatccagac aaaatcttag tgaaaaatcc tgataatata aaagatacag aaaaaaatgc
    17701 cattattgaa aaattgaaag aggcaaataa aaatcatcca gcaggagctc caacctttgc
    17761 taaaggtgaa ggagagcatg caaatgatat tgtagcaact tattcagatg gtacaactta
    17821 ttatgcaccg ttaaatgatg tgacaaaata tgcgaggtag tggctgtacc actcacttat
    17881 tcacctcccc gtgatttgta gtagtgatag gctttctcac tattattata aaacaaaata
    17941 aagatcacaa cactttttca ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta
    18001 taaatatgaa aagtatagtc actagcatag atgagcgctt gcgtactcgc ctacgagtga
    18061 ttatctggaa gcaatggaag aagaaatcga gacgattatg gggattgctt aagttagggg
    18121 ttcctaaatg gatagcagat aaggtatctg gctggggcga ccactatcaa ttatattaaa
    18181 atgaaataag aataggacga atcgatcagg gaagtcaaat cgatttctaa caatatttta
    18241 gaagtagagg tata
//
LOCUS       DAVMCG010000042        16176 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVMCG010000042 DAVMCG010000000
VERSION     DAVMCG010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.043"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            18..1324
                     /locus_tag="VYP66_001686"
                     /pseudo
     CDS             18..1324
                     /locus_tag="VYP66_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1423..3045)
                     /gene="groL"
                     /locus_tag="VYP66_001687"
     CDS             complement(1423..3045)
                     /gene="groL"
                     /locus_tag="VYP66_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1851200.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3061..3345)
                     /gene="groES"
                     /locus_tag="VYP66_001688"
     CDS             complement(3061..3345)
                     /gene="groES"
                     /locus_tag="VYP66_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1851201.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVVTGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(3501..3896)
                     /locus_tag="VYP66_001689"
     CDS             complement(3501..3896)
                     /locus_tag="VYP66_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1851202.1"
                     /translation="MYNKVILIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(3974..4735)
                     /locus_tag="VYP66_001690"
     CDS             complement(3974..4735)
                     /locus_tag="VYP66_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEV1851203.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKA
                     EFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK"
     gene            complement(4777..5403)
                     /locus_tag="VYP66_001691"
     CDS             complement(4777..5403)
                     /locus_tag="VYP66_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1851204.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(5419..5736)
                     /locus_tag="VYP66_001692"
     CDS             complement(5419..5736)
                     /locus_tag="VYP66_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1851205.1"
                     /translation="MIQPASLEELASLVEKAGKKVFIFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(5733..6032)
                     /locus_tag="VYP66_001693"
     CDS             complement(5733..6032)
                     /locus_tag="VYP66_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1851206.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(6369..6560)
                     /locus_tag="VYP66_001694"
     CDS             complement(6369..6560)
                     /locus_tag="VYP66_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEV1851207.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(6721..7395)
                     /locus_tag="VYP66_001695"
     CDS             complement(6721..7395)
                     /locus_tag="VYP66_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851208.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYVK"
     gene            complement(7401..7847)
                     /locus_tag="VYP66_001696"
     CDS             complement(7401..7847)
                     /locus_tag="VYP66_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1851209.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(7961..8464)
                     /locus_tag="VYP66_001697"
     CDS             complement(7961..8464)
                     /locus_tag="VYP66_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1851210.1"
                     /translation="MKNYQEWYRNISSRLTSCPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(8461..8823)
                     /locus_tag="VYP66_001698"
     CDS             complement(8461..8823)
                     /locus_tag="VYP66_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1851211.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(8889..9884)
                     /locus_tag="VYP66_001699"
     CDS             complement(8889..9884)
                     /locus_tag="VYP66_001699"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1851212.1"
                     /translation="MDKPMLVFKRFGHQIYLMVQKEAKRCGIEFMGGPQGQVEFKDET
                     FRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYDVSAGEILVDGVN
                     VQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHIDGVDTKAMTRSE
                     VHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHHFIMTLPDGYDII
                     LDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQKAMDRLMEGRTS
                     FVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNSQFTEDEAEE"
     gene            complement(10008..10724)
                     /locus_tag="VYP66_001700"
     CDS             complement(10008..10724)
                     /locus_tag="VYP66_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1851213.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11605..13020)
                     /gene="ply"
                     /locus_tag="VYP66_001701"
     CDS             complement(11605..13020)
                     /gene="ply"
                     /locus_tag="VYP66_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1851214.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13031..13363)
                     /locus_tag="VYP66_001702"
     CDS             complement(13031..13363)
                     /locus_tag="VYP66_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851215.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13434..14042)
                     /locus_tag="VYP66_001703"
     CDS             complement(13434..14042)
                     /locus_tag="VYP66_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851216.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14055..14513)
                     /locus_tag="VYP66_001704"
     CDS             complement(14055..14513)
                     /locus_tag="VYP66_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1851217.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14638..15037
                     /locus_tag="VYP66_001705"
                     /pseudo
     CDS             14638..15037
                     /locus_tag="VYP66_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15802..16062)
                     /locus_tag="VYP66_001706"
     CDS             complement(15802..16062)
                     /locus_tag="VYP66_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851218.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
BASE COUNT         4777 a         3642 c         2902 g         4855 t
ORIGIN      
        1 tcattagaaa gattcatatg gaacaattac attttatcac aaaactgctc gatattaaag
       61 accctaatat ccagatttta gacatcatca ataaggatac acacaaggaa atcatcgcca
      121 aactggacta cgacgcccca tcttgccctg agtgcggaaa ccaattgaag aaatatgact
      181 ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg tatgccttct agaattctcc
      241 ttagaaagcg tcgtttcaag tgctatcact gttcaaaaat gatggttgct gagactcccc
      301 tggtaaagaa aaatcaccaa atccctcgta tcatcaacca aaagattgct caaaagttaa
      361 ttgaaaaaat ttctatgact gatattgccc atcagctggc catttcaact tcaactgtca
      421 ttcgcaagct caatgacttt cactttgagc atgatttttc tcggcttcca aagattatgt
      481 cttgggatga gtatgccttc actaagggaa agatgagttt cattgcgcaa gattttgata
      541 atcttaatat tatcactgtt cttgaaggca gaacacaagc tgtcatccga aatcactttc
      601 ttcgctacga tagagccgtt cgttgtcaag tgaaaatcat tacgatggat atgtttagtc
      661 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      721 ctcccagact gtttcactcc cgaatgctaa aatcgtgttg gatcgctttc acattgtaca
      781 acatcttagc cgtgctatga gtcgtgtgcg tgttcaaatt atgaaccaat tggatcgaaa
      841 atcccatgaa tacaaggcta tcaagcgcta ctggaagctc atacaacagg atagccgtaa
      901 actgagtgat aagcgatttt atcgtcctac ttttcgtatg catttaacca ataaagagat
      961 tttagacaag cttttgagct attcacaaga cttgaaacat cactatcagc tctatcaact
     1021 cttgctgttt cactttcaga ataaggaacc ggagaaattt ttcggactta ttgaggacaa
     1081 tcttaagcaa gttcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
     1141 aaagattatc aacgcccttc aactacacta ttctaacgcc aaaccggaag cgaccaataa
     1201 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
     1261 acggattttt atcgctttga acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc
     1321 ttagctgact tcaacccact acagttgaca aagagcctat aaaaagaagg gttagtcatt
     1381 ccctcctttt gtgtttttta taagttgttt tctatagaaa gcttacatca tcccgcccat
     1441 catgcttgga tccattgctg gagctggggc tactggttct ggtttattgg ctacgactgc
     1501 ttctgttgtc aaaatcaagc tggctacaga tgctgcattt tgtagggctg aacgactcac
     1561 tttaactgga tcaatgatac cttgatcaat catgttaacc cactcgccag ttgctgcgtt
     1621 aaatcctata ccaagctcag catttttcaa acgatcgata acgatagatc cttcaaatcc
     1681 tgcattgtga gcaatttgac gaacgggttc ttccaaagca cggagaacaa tattacgtcc
     1741 tgttgcttca tctcctgtca attccaaggt agcaacagct ggaatcacat tggcaagagc
     1801 tgttccacca cctgcaacaa taccttcttc aacagctgca cgagtagcgt tgagggcatc
     1861 ttcaatgcgg agtttcattt ctttcaactc agtttcagtt gcggctccaa ccttaataac
     1921 cgctacacca cctgacaatt tggccaagcg ttcttgcaat ttttcacggt caaattcaga
     1981 agttgtagtt tcgatttgag acttgataac cgcaacacgg tgagaaatcg cttcaggatt
     2041 tcctgcacct tctacaataa ccgtgctatc tttgtccacg gtcactctcg ctgcttgacc
     2101 aagagcttca attgtcgcat ctttcaactc aagaccaagg tcttctgtga taactgttcc
     2161 gcctgttaag atggcgatat cttcaagcat ggctttgcga cggtcaccaa aaccaggtgc
     2221 cttgactgct actacgttga aggttccacg aatcttgttc aaaacaagag ttggaagagc
     2281 ctcgccatcc acatcatccg caataatcaa gagtggacga ttgctttgga gaatgctttc
     2341 caaaagtggc aagatttctt ggatattgga aattttcttg tctgtaatca aaatgtacgg
     2401 attttcaagg tcagccacca ttttttcgct atctgtcacc atgtactgtg aaaggtaacc
     2461 acggtcaaac tgcattcctt ctacgacttc aagctctgtt tccataccac gtgactcttc
     2521 gatggtgatg acaccgtctt tgccaacttt ttccattgct tcagagatgt actcaccaac
     2581 tttttcagaa cgagaagata cggctgcaac ttgagcgata gcttctttat tggcaacagg
     2641 gatggcgttg tttttcaaag cttcaactgc tgcggcaact gctgtttcaa tcccacgacg
     2701 aataccgatt ggatttgcac ctgctgtgac gtttttgatt ccttcacgga cgatagcttg
     2761 ggtcaagact gttgcagtcg tagttccgtc acctgcgata tcattggttt tagaagctac
     2821 ttctgatact aacttagcac ccatattttc aaaatggtct tccaattcga tttctttggc
     2881 aatggtcaca ccgtcattgg taatcaaggg tgaaccgaat gacttttcaa gaacgacatt
     2941 gcgacctttt ggtcccaagg ttactttaac agtgtctgca aggatatcga caccacgaac
     3001 catggctgaa cgggcatctg atgaaaattt aatttctttt gacatactta ctttctcctt
     3061 ctattcctca atgattgcca aaatgttagc ttcgcctacg atgatgtact tttcatcgcc
     3121 atctttgaca tcaagacctg cgtgggcttc aactaagaca cgatctccag ttttaacact
     3181 tggagcaacc aagtcaccgt tcaaggtacg aacaccttgt ccagtaacca caacttgagc
     3241 tgttttggtt ttttcttggg ctgagcctgc aaggacaaag cctccaacag tttgttcttt
     3301 ttcttctatt tttaagacca cacggtcccc taatggtttc aacatctgat ttcctccata
     3361 atgagataga tattattagc actctttgaa cttgagtgct aattcatagt tctattgtat
     3421 cacttggtca gaaataatca agaaaaaagt ctgactttct caagataaaa agcctgagac
     3481 caactcagac tttttaattc ttaaaatggc aattcttcct cttccaagac caaatctgcc
     3541 aaatcttggc ctgcattatt ttcacgcata gcacgttggg cacgactttc caagagttgg
     3601 aatcctgtga caagtacttc ggtcacgtag ttcatttggc catttttctc aaagcgacgg
     3661 gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg ttgcgtagct tgccaaagtt
     3721 tctgctagtc tgccccatag gaccatattg acaaaatcag cttcacgttc accgttttgg
     3781 tctttgtaac gacggttcac agcgatagtt gctcgcgcta ccgacttgtc attgttggtt
     3841 ttgtgcaatt ctggtgtaga cgttaaacgt ccaatcaaga taactttatt atacatattt
     3901 tcttcctcct acttatctat tcgtaggaaa tcaaaaaaag ttacagaaat ttgtaacttt
     3961 tcgagaaaat tttttatttt ttatgaacca tgaaacctgt cgcctgttga ttggccataa
     4021 tggtcatatc tgtaatctga acacgacgag gttgactagt cacatagact actgtatctg
     4081 caatatcctg agcttgcaaa gcttctattc cttggtaaac ggacgcagct cgttctttat
     4141 caccatgaaa acgcactgta gaaaaatctg tttcgacaat tccaggctga atggtcgtca
     4201 ccttgatatc cgttgcgatg gtatcaattc gcagtccatc tgaaaaggtc ttaactgccg
     4261 ccttggtggc tgagtaaaca gctgcaccag cataggcata aattcctgcg gttgacccca
     4321 tattgataat atgaccttga ttggctttta ccattgctgg caagaaacag cgagtgactg
     4381 ccatcaaacc tttgacattg gtatccaaca tggtcagcat atccaactct tcatagtctt
     4441 gatagggagc taagccaaga gccagtcctg cgttattgac caggatgtca atctgaccta
     4501 tcgtttctaa aatatcagag cagacagtct ttaccattgt catatccgtg acatctagga
     4561 gaaaagtcca aactgtttga tttggaaaag tttctgcaaa ctccgcctta agagcttcta
     4621 gtctgtctat ccgtcgtcct gttagaacga catcctcacc ctgctccaga taagcacgcg
     4681 caatcgcttc accgattcct gatgtcgctc ctgtaatcac aacatttttt gccatcttat
     4741 ttccttctag ctggtctatc agatattaac aacttcttag gcagtccagt gtttcgctgg
     4801 gtcgaacggt gttccgacaa cttggtcttc tgataattca agcaccccac gtttttgtgg
     4861 agcatttggc agatgcaatt cacgaggact gcacatcata ccaaaactct tttcaccacg
     4921 aagttcacct gggaaaatga gattcccttt tggcatcata gctccaggaa gcgcgacaat
     4981 ggttttcaac cccacacgcg cattgggagc tcctgcaacg atttgtacag tcttatcact
     5041 tgcgactgca acttggcaga tgttgaggtg gtcactatct ggatgggcta ccatctcaac
     5101 aatttcacct acaacaaact taggttcctt atcattaaca atttcttctg taaaaccttc
     5161 cgcctgcaac tcttggttca aacgagcgac ttgctcatct gtcaaaaaga cttgaccgcg
     5221 ctctgcaatt tcaaataaac ttgaaacttc gaaaatattc caagccactg tttccccatt
     5281 atctttgaga aaaacacggg ctaccttgcc tttgcgctcc acatccagtt tggcatctcc
     5341 gctatttttc acgatgacca taaggacatc accgacatgt tctttattat atgtaaaaat
     5401 cattgtttcc tttttctcct atttcagtcc tgctaaaaag tcattgattt gttgcttgct
     5461 tttacggtcg cgattgacaa aacgaccgat ttccttgtcc ttttctagaa caacaaggct
     5521 aggaattccg taaacatccc agagtttggc caaatccata tactgatctc ggtccattcg
     5581 aataaaggtg aactctggat tggtctcctc aatctctggt aaggcaggat aaatataacg
     5641 acaatcgcca caccagtctg ccacaaaaat gaagaccttc ttgcccgctt tttccactaa
     5701 agatgctaat tcttctaaac ttgctggctg tatcataaga cttcctcctc atagactagg
     5761 tcttcatttt catagacaaa ggtataatga cggccatcct caaaaatgac gccaccaacc
     5821 aagctctcca gactgctttc gtaaacttga acataaaggg tcgcaatttc ccccatgtcg
     5881 gaaaaatggt ctcgcacaat ctctgtcaac tcttcctgag tcttcatgag cttacggtca
     5941 tctgcaactt ttttcgtagc aagagcaagg cttccgatac ctagcagagc caagcctgcc
     6001 atccacattt ttttagcttt cataccattc attttaacac aaaaaaggct tcaggacaaa
     6061 tgaggaagca gcagaaaagc aagtaaaaag cctcttcctt taaggaaaag gacttcttat
     6121 actcaatgaa aatcaaagac caaactagga agctagccgc aggctgctca aagcactgct
     6181 ttgaggttgt agatagaact gacgaagtca gctcaaaaca ctgttttgag gttgtggatg
     6241 aagctgacgt ggtttgaaga gattttcaaa gagtattatt cttattgcca ggcacctaag
     6301 ttgccaacgt agtaactatc aggtgtgtag gtattgcgaa gcatcttacc tgatgaagcc
     6361 agataatact acttgccatt gtctttgacc caatcattcg caatcatgga accagaagaa
     6421 cttacataat accattctcc cttgtcataa acccaagtac tgactttcat ggttcctgag
     6481 caattaaagg caaaaaaact gtccaatatc attcgttttt taaaagcatt tgacactaca
     6541 tcatctacgc tgtagtacat agatacatca aacgtaaaag ccaaaatatc gaaaaatata
     6601 caacttttaa aggcagcatt tcatttttta aagtctaaca accatagaac tgaaatcaga
     6661 gcaaggcatc aatttcctac tcttagtacg tctattttga tggttgaagt gaagattttt
     6721 ttatttaacg tagacaattt ccaacttccc aaaagccaca tctccacgga taatcaaggt
     6781 tttgctggtt ggggctacag gagcgtcagc cttagctgca ccaaaggagg tttctacttt
     6841 caaatctaca cgccagtgtt gtggaacata gacggttgca ttcccgaagg ccacttcaat
     6901 atttaaagtt gcaaaatcac ctagcatctc tgcattatca tagtagattt tagcatcccc
     6961 aaaagcgact tccacttggt catctacgag atcttgatct tgcttataga aggtcccgct
     7021 accaaaagcg acttccttat ccgtgacgac tgtttttttc ccattgtacc accatttttt
     7081 ttcattccag aacttacttg aatgcgtcag ataaccaaca ccaagtacca ccaagatgct
     7141 agcccaaata agagaatgat tggtaactgg taacaagtca taagcgtaat ttgcaatgat
     7201 gagcgccagt aaacctgtaa aaactgccga agtgagatga cgtctaagga tggactcaat
     7261 ggacttataa gcaaaaaaaa caatacctag taaaggccat attttaccat ccaaagaagg
     7321 aattccaaaa ttcccttgca gcaagatcca agctgctaaa accaataaaa caataccaaa
     7381 tgctttcttt ttcatgtttt ttacctcatg tttcttagat tttcttttag gagggattgg
     7441 taatgccgtg agacatgaac ctccttgtgc gtctgataaa aggaaatggt gcccgttcct
     7501 gaaaaggact tgtccactga gtaaatctga cggatgtttg cgatcgttga cttggaaact
     7561 cgattaaaat agcgaggcaa gatagactcc aactcataga gcttgaggcg aacctcataa
     7621 gcttccttct ggttatgagc gtagatcttg ctcccttctg tttcaaagaa gagaatttct
     7681 gacaggtcta gataatattc acctgtcccc ttgtaaaaag tcaacctcgg agcctttgac
     7741 tcttgcaaga ggcgttgcaa gtctgcaatt tcatctgtca aagtgggggt cttgatgaca
     7801 atttcagtct cctctaaatt gccgtcaatc tcaattcgta acttcatcac atctcctttc
     7861 tgactctact atatcaaagc taagttagga atacaagggc aaaaaagcaa gtggtcaatt
     7921 tgaagcagta agtggttgta ggactagctt aacttacatg tcagaatagg aagaaaagga
     7981 atccccacac caaaccacaa gcatagccaa ccaagacatc cttgggataa tgaacacccc
     8041 ctaaaaccct caccaacccc agcaaagctg aaaagatcaa gcatactaag ccaataggta
     8101 gactagcatg cagacaggcc atggagatga tagttgccga aaagacatgg cgactgggca
     8161 tcgaccgtcc cgaactatcc ttatcaagaa ggggacagat atcccaagtt tcataaggtc
     8221 tcgggtgatt gattttctta cgaaacaggg acaaggccac aaaacctgat gcaggaataa
     8281 gcacataaac cccaacttgc tgaccaagtc ctagttgcag gtaagtggtg actagcaaga
     8341 tcagatagac caggggcatg gcgactgtca tcaaacgatt gaaactgcgt aataggaata
     8401 aaagaattgg acaactagtt agtctggagc tgatatttcg ataccattct tgataatttt
     8461 tcatttatgc ttctcatact tttctagaac ttgttgagat gttttcccct tggcaagcca
     8521 atccactagc ttgtccaagc gacgtatttc ctgcatcaga ggatcatcaa tttcctcaat
     8581 acggacaccg caaatcttcc ctgtaattgc aattcgttca gggacataat atggtgcttg
     8641 tctaaaaaaa tctccgtaag taacatccct atccagacaa gcaagaacat cactcacttc
     8701 ataccctgtc aaccaactgg tcacttggtg aactgactct gcctttccac cctttcgctc
     8761 aacttttgca atcaaggcta agtagacagc agcaaatttc atattgtata atttctgact
     8821 catacttctc tctttctatg tgtactagta taaataagaa aaagaaggcc gtcaagcctt
     8881 cttttgattt attcttctgc ttcatcttct gtaaattgac tattgtacaa gtcagcgtag
     8941 aagccacctt gcgccatcag ttcctcatag ttgccttgct cgatgatatt tccatctttc
     9001 atgaccaaga tcaagtctgc atttcggatg gttgacaagc ggtgggcaat gacaaaggat
     9061 gtgcgtcctt ccatcaaacg gtccatggct ttttggatca attcctctgt ccgtgtgtca
     9121 acagaagaag tcgcctcatc caaaatcaaa agcggtgcat ccttaagaag ggcacgagca
     9181 atagtcaata gttgtttttg tcctacagac aaggtcacgg tgtcatccaa gatgatatca
     9241 tagccatctg gcaaggtcat aataaagtgg tgaattccca cagccttact agcttccatc
     9301 attcgttcat cactaatccc tatttgatta tagatgagat tgtctcgaat agttccttca
     9361 aagagccagg tatcctgcaa gaccattgaa aaggcatcat gcacttctga acgcgtcata
     9421 gccttggtat ccacaccatc aatatgaata cttcccttat caatctcata gaatttcatc
     9481 aaaagattga caatggttgt cttaccagtc ccagtcggcc caacaatggc aaccttttga
     9541 ccagcatgag ctgtcgcaga gaagtcatag tcttgaacat tgacaccgtc caccagaatt
     9601 tctcctgctg acacgtcgta gaaacgtgga atcagattga ccagagttga tttaccagaa
     9661 cctgttgacc caataaaggc cactgtttga ccagtttctg ctttaaagct aacatgttca
     9721 ataactgcct ccgaatttgc cgcatagcgg aaggtctcat ccttaaactc gacctgacct
     9781 tgcggcccac ccataaattc aatgccgcaa cgtttggctt ccttttgcac catcaggtaa
     9841 atttgatgac caaaacgctt aaagactaac atcggtttat ccataatctc ccccttctaa
     9901 ataaaaatag ttctctggag aataattaaa tttctatgag aactattttc ttgattaaaa
     9961 aaatcccaag tgattttctc acttaggatc atgttctata ggttaaatta aaacccatct
    10021 acgttcgtat aaatcttttg gacgtcttcg tcgtcttcaa gaacgctgta aagtttttca
    10081 aaggtttcaa ggtcttcgcc tgacaattcc acttctgact gaggaatcat ttccaattca
    10141 gtcacttgga attcttcaat accagactca cggagagcaa cgatagcctt gtgaaggtca
    10201 gttggcgctg tgtaaactgt gattgtacct tcttgtgctt ctacgtcatc cacatccaca
    10261 tccgcttcga gcaattgctc aaagactgcg tccgcatctt cacctccaaa tacaataaca
    10321 cctttgttgt caaaaaggta agaaacagaa cctgaagcgc ccatgtttcc gccgttttta
    10381 ccaaaggctg cacggacatt ggctgctgta cggttaacgt tagaagtcaa agtatccaca
    10441 attagcatag agccatttgg cccaaaacct tcgtaacgtc cttctgtaaa ggtttcgtct
    10501 gtgtttcctt tggctttatc aatcgcttta tcgataatgt gttttggcac ttgggcttgt
    10561 ttagcacggt cgataacgaa tttcaaagct gagtttgatt ctggatctgg atcacctttt
    10621 ttagctgcta catagatttc tacaccaaat tttgcatata ctttagagtt agctccatct
    10681 ttagccgttt tcttggctac gatattggcc catttacgtc ccattaggaa tctccttttt
    10741 tcacatttta atctttctta ttataacaca agtttttttg attttcacta gaggaaatgg
    10801 attttattag caaatcaagc taggatagca ctttacctgc taagatggtc ttgcctttct
    10861 atctttatca acaggcactc atccacattc aaaaaacaaa ctagaccatt atctgcaaat
    10921 agaaagtttc agccaagttt gacaaagtca gctcaaatta ctgtttgaag tttgtagata
    10981 taagcgacaa aaacaatcat actgcacctt ttgttgacag tctactccag acatatcata
    11041 gttcaagtaa atactttgaa attcaacagt tcttataggc gctattgtat tctaagaaat
    11101 caatagaaga gtttctaagc aaacctctaa tactcaataa aaatcaaaga gcaaactaga
    11161 aagctagcct caggttgctc aaaacactgt tttgaggttg cggatggggc tgacatggtt
    11221 tgaagagatt ttcgaagagt ataatttacg tgttcccaag atggagaagt tagactagta
    11281 cactggcact tctaaaacat tgctagcaat tgatttgttc atatttaatt tcattttttc
    11341 cataaatggg tattagatat aaacagcaaa atatttccga tacgtgtcgt tcttgaattt
    11401 ccaatcatct aaaacaagta aaggataatc aatcccctgt atatcaagga attggctacc
    11461 ctttttactt ttttacacat tctgtttgat agattcattt taacatcacg agcatactcc
    11521 aatggaaatc gctaggcaag agataaactt tcagatatcc gcagagagat catcgcctct
    11581 ttttgtcgca agcattctcc tctcctagtc attttctacc ttatcttcta cctgaggata
    11641 gagagttgtt ccccaaatag aaatcgtccg cttacgcact agtggcaaat cggttttttc
    11701 ataaaccgta cgccaccatt cccaggcaag cccggtacac tctctaattt tgacagagag
    11761 attacgaaca ttccctttta aaggaatact agtggtaaag tgagccgtta aatcctgccc
    11821 atttctgtcc caagccttag gagtcaagac ttccttacct tgatgatcat aggataattc
    11881 attccaagta atataatatt gggcaacata ggcaccacta tgatccagca gtaaatctcc
    11941 gtttctgtaa gctgtaacct tagtctcaac atagtctgta ctattttgaa aggtcgcaac
    12001 tacattgtca cgtaaaaaag aagttgtata ggaaatcggc aagcctggat gatctgctgt
    12061 aaagcgactg ccttcttgaa tcaagtcctc taccatatcc accttgcctg ttacaactcg
    12121 ggcacccgaa cttgggtcgc cccctaaaat aaccgccttc acttctgtat tgtccaaaat
    12181 ctgcttccac tctgtctgag gagctacctt gactcctttt atcaaagctt caaaagcagc
    12241 ctctacttca tcactcttac tcgtggtttc caacttgaga tagacttggc gcccataagc
    12301 aacactcgaa atatagacca aaggacgctc tgcagaaatt cctctctgtt ttaaatcctc
    12361 taccgttaca gtatcttgaa acacatctcc tggattttta acagcgtcta cgctgactgt
    12421 ataataaatc tgcttaaaat taacaatctg aatctgcttt tcgcctgaat ggacagagtt
    12481 aaaatcaata tcaagagaat tccctgtctt ttcaaagtca gaaccaaact tgaccttgag
    12541 ttgttccatg ctgtgagccg tgattttttc atactgcatt ctagctggga cattattgac
    12601 ctgaccataa tcttgatgcc acttagccaa caaatcgttt accgctccgc gaacacttga
    12661 attgctgggg tcttccactt ggagaaagct atcgctactt gccaaaccag gcaaatcaat
    12721 actataagtc atcggagcac gatcgaccgc aagaagagtg ggattattct ctaacaaggt
    12781 ctcatccact acgagaagtg ctccaggata gaggcgactg tcgttggtag ctgttacaga
    12841 aatatcactt gtatttgtcg acaagctccg cttctttctt tcgataacaa caaactcatc
    12901 gggtagctga ttaccctctt tgatgaaacg attttcaata ctttctccct gatgggtcaa
    12961 gagtttcttt ttatcgtaat tcatagctag tataaagtca tttactgctt tatttgccat
    13021 cttctacctc ctaataagtt cctggattga gttgcataaa ctcagacttg ttcagcgaaa
    13081 tcagccgtgg ttggactaag taatccaaaa tttcctcgta caattcttct gagacattgc
    13141 gtcgccgtct ggctaaataa gaagtcggaa tgaccgtatt atccaacata aataccttat
    13201 ctaagtcaat caaggttggt cttgtaaaag gattacgagc tagatccggc tcttctatca
    13261 taaagttctt gaccaaacgt ctggtcaaga gagctggttt gaaggtctga tttttaacca
    13321 actctttgtt tttagtcatg ctgttgtcaa tacagatata catatgattc ttcacagcca
    13381 aatcgctact aatagtcgga aaaggcaaat aaagagctac aacatctcct ctcttaatca
    13441 agcaagagca cccccttttc tcctaatgta acatagacag gattgaccaa gtcttctgat
    13501 tgactcagaa tttccaaagt ttgagtttgg cgcgctgtca atttagtagc atcttgtctc
    13561 ttcaatacaa aatgcttgtc gccaataacc ttgacaatat aatccttctc caaagctgac
    13621 tggtaaatcc acatcagatg ttgtctgtcc tgagaactca agagagaagg attttcaagc
    13681 ctcccgatag tctgataaaa atcaaaaaca ggagctaact cctgccaatc tgattggcta
    13741 gttgtcaagg ctagaaaaag ggctttgcga gctgatactt cttggttagc cttgagagtt
    13801 actttcccct ccaagttttt tagaaatcgg gaaactccag aaagcaaatt tttctctaac
    13861 tgcgagaaat aaaaaccttt cgttcccaga cataagtctt tcatgtcgct ttctctagca
    13921 aataagagct caaacatttg atagtaaaag aaaaatatct ggcactgggt cgcgctcatc
    13981 ttttccttat cggcttcttt ttttaaccag agcaagggcg acaggtagct ggattgagac
    14041 atttcctcta cctcctactc ttttttaact ggagcatctg cactagctgc cacttctttt
    14101 gactggatac tttcccactg gttaatctcc tctgagataa gaccttcgca tgtcttgaca
    14161 aatagggcaa aagccttggt ctttcctgca tatttctccg tttggcattg atagaggaat
    14221 ttttctttct ccaggagttg cgcagttttt tggtaagaaa tccaattttc ctttgcatta
    14281 tacaaattga taatcccctc acacagcaag ccgagactgg ataaggcaac cgaaatcaaa
    14341 cggtagcgat cacctggcat aggaatagca caaaagacag ctatgaggaa acctgccacg
    14401 atttctgtta tttttaatac cttatagcgt ctacgatgtt gaacgctttt ctttaaaaaa
    14461 tgagctatct gtacgtctaa tcgctctgtc aggtacattt cttctggcgt catattcgta
    14521 actcctttca tttactttga taatcatagt ataacatatt tgaatatcaa agtatagtaa
    14581 aaactggact ataacttatt agactccctg cgaaacaaaa tatggtatag tagttctatg
    14641 aatgatgaag caagtaaaca attaactgat acacgattta agcgtcttgt tggtgttcag
    14701 cgtaccactt ttgaagagat gttagctgta ttaaaaacag cttatcaaaa aagtcggaca
    14761 agctggtaaa atcttggctg acagtaatta tcaagggctc atgaagatat atcctcaagc
    14821 acaaactcca cgtaaatcca gcaaactcaa gccactaaca gttgaagata aagtctataa
    14881 ccatgcgcta tctaaggaga gaagcaaggt tgagaacatc tttgccaaag taaaaacgtt
    14941 taaaatgttt tcaacaacct gtcgaaatca tcgtaaacgc ttcggattac gaatgaattt
    15001 gagtgctggt attatcaatc atgaactagg attctagttt tgcaggaagt ctattatata
    15061 tatgcacaga catatgaaat ctttttgata cagccttctt tttacataga gagacagcag
    15121 ttatgatata tttatccatt cacaacatct tctgtaccaa tactacaata attggtacat
    15181 tttgattaca caatcgtttc aaaaaatatg atggaagact gagtatttta tagtaatttc
    15241 cttcctatca actagatcaa ccagttgagt gttgaatatt gaaacaccct agcctcagca
    15301 aaggactatg atcagcattt cctagccaat aggacgctcc aaatcaccta ttctaagtcc
    15361 atcactagct tggtcagtaa gatacagact gcaaggcaag actgacgtgg ttgatgagat
    15421 tttggaagag tattacaatc atagattcac cagtagactt gaccgcagat ttaactatag
    15481 tagattgaaa ctagaatagt acacttctgc ttctaaaaca ttgttagaaa tcgatttgac
    15541 tgtcctgatc aatttgtcct gttctcgttt cattttacta tattaaaaaa ccacctgaaa
    15601 caaatcaagt gactagagga taaaaacaaa gactgggcaa aaagttttga aaagcaaaaa
    15661 acgcataata tcaggtcttg aaaaaccttg atactatacg tttgattgtg ggaagattga
    15721 cttcattttc tcctgaaatt gaagtttttt ctagtttcca ggtatagacg aattcaatat
    15781 agccatctcg ctacaattat tttaaccatc gaaaaaattt ttcagaattt caaaaatttc
    15841 attttgatct aatgaaatgt catcattttg aagaatagtt gacttcacaa gctctaattc
    15901 tatcacaaag cggtgcatgt ctgcttttac cgcactactt gatgttatag ccgataactt
    15961 ttcatctcct agcaaggaag ctgtcaaacg ggtaatgtca ttcaaatgct ttttaatgga
    16021 cttacttaaa ccttgagcac ctgtagcaga gcgttccctc atatccagcc aagctttagc
    16081 cttaaaaata attaatactc aatgaaaatc aaagagcaaa ctaggaagct agctgcaggc
    16141 tgctcaaaac actgttttga ggttgtagat ggaagc
//
LOCUS       DAVMCG010000043        15284 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVMCG010000043 DAVMCG010000000
VERSION     DAVMCG010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.044"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            162..461
                     /locus_tag="VYP66_001707"
     CDS             162..461
                     /locus_tag="VYP66_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1851219.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSFIVSRWNGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            532..2553
                     /locus_tag="VYP66_001708"
     CDS             532..2553
                     /locus_tag="VYP66_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1851220.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTSEVFEQELENFANSEQSLIARRIVEPSKDGTTHFIYATYGQGTLPKEFQEASQ
                     ENRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDIENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKVGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2555..3196
                     /locus_tag="VYP66_001709"
     CDS             2555..3196
                     /locus_tag="VYP66_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851221.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSIFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3300..4652
                     /locus_tag="VYP66_001710"
     CDS             3300..4652
                     /locus_tag="VYP66_001710"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1851222.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALVKGIPVLTE
                     VELAYLISEALIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGAFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLASKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4654..5712
                     /locus_tag="VYP66_001711"
     CDS             4654..5712
                     /locus_tag="VYP66_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1851223.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQTHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5722..6942
                     /gene="divIB"
                     /locus_tag="VYP66_001712"
     CDS             5722..6942
                     /gene="divIB"
                     /locus_tag="VYP66_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1851224.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVTSSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLFVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            7175..7876
                     /gene="pyrF"
                     /locus_tag="VYP66_001713"
     CDS             7175..7876
                     /gene="pyrF"
                     /locus_tag="VYP66_001713"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1851225.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QLIKQATNPDFICLTPGIRPQGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            7910..8542
                     /locus_tag="VYP66_001714"
     CDS             7910..8542
                     /locus_tag="VYP66_001714"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1851226.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            9221..9985
                     /locus_tag="VYP66_001715"
     CDS             9221..9985
                     /locus_tag="VYP66_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851227.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9985..10737
                     /locus_tag="VYP66_001716"
     CDS             9985..10737
                     /locus_tag="VYP66_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851228.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10747..11445
                     /locus_tag="VYP66_001717"
     CDS             10747..11445
                     /locus_tag="VYP66_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851229.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLANWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11442..12089
                     /locus_tag="VYP66_001718"
     CDS             11442..12089
                     /locus_tag="VYP66_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851230.1"
                     /translation="MNEIITLKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12169..13034)
                     /locus_tag="VYP66_001719"
                     /pseudo
     CDS             complement(12169..13034)
                     /locus_tag="VYP66_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(13046..13808)
                     /locus_tag="VYP66_001720"
                     /pseudo
     CDS             complement(13046..13808)
                     /locus_tag="VYP66_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(13809..14096)
                     /locus_tag="VYP66_001721"
     CDS             complement(13809..14096)
                     /locus_tag="VYP66_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1851231.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            complement(14106..14486)
                     /locus_tag="VYP66_001722"
     CDS             complement(14106..14486)
                     /locus_tag="VYP66_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1851232.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(14446..15126)
                     /locus_tag="VYP66_001723"
     CDS             complement(14446..15126)
                     /locus_tag="VYP66_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1851233.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATTYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVELPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFG
                     NPSTLSRK"
BASE COUNT         4614 a         2647 c         3302 g         4721 t
ORIGIN      
        1 taatatagta aaacatctaa aaaattcgat tttttccttg acaacaaata ataaaaatgt
       61 tattcttatc acataagaaa gcggtttcaa taaaagagag aggaggattt attttgttgc
      121 attgttgctc agggtgtgct ttttttgaaa gaaaaaataa aatgaaaacg aaaaaacata
      181 gattacttgc tctagctctt atttcaagtt ttacattatt gggagctgca tcagctgctg
      241 tacaatatcc agatggagga gtatggacat atggagaagg ttcaggaggt ggttgggctt
      301 tttcaaatta ctatcatggt aaaaaatatc attattcatt catcgtgagc agatggaatg
      361 gtcattctga taaaggagaa gctcctgctg gaaaaacctc ctatgcatgg atttggacta
      421 aatggggaga acaagtagca ttttactgtg attatgacta atcgttcatt gatttaaatc
      481 gttccccttg taagaaatta cagggggaat tttgtttaca aggagtctac tatgaagaaa
      541 ctattcatat tattatcaac tttttttctc agcttcttcc ttgcttggat tattgtctta
      601 cgtgcgccac aatatttata tgcaagctat gattccgttt ctttacttcg tgtcaaaaaa
      661 gatactcagg aaccgacgag tgaggtattt gaacaggaat tggagaattt tgcaaactca
      721 gaacagagtt taatagctag aagaattgta gagccgagta aggatgggac gactcacttt
      781 atttatgcaa cttatggtca gggaacttta ccaaaagaat tccaagaagc tagccaagaa
      841 aatcgtgaac gtagtgatcc gctaaatagt tatctccttt tgtcaggctc cttgacgaaa
      901 gaaaagcttg ccgataaatt aggagatttg ggttataaag caagtgctga ccgaaagata
      961 ccgccctatt ttcttgcttt tcgaatatta ctaaatcccc ttattttaat tagtttagca
     1021 atatttggct tatctttctt tgctttagtg attatcactc ggattaagga aatgagagca
     1081 gcaggtataa aactcttttc tggtcagact ctcttatcca tcatggggca ttctttatct
     1141 actgatatca aatggctcct tctatcagcc ctcctttcct tcctaggtgg gggagtcgtt
     1201 ctttttagtc aaggtttgtt ttatcctatc ttgttagcca cctatggttt tgggattagt
     1261 ttctatctgt tgtttttatt ggcgatttca attttactaa tgctccttta tctaatgagt
     1321 ttgaattaca aagcattagt tcccgttatt aaggggagat taccccttaa acgcctgatg
     1381 attttaaccc tattgtgtca gttggttgct gtctttacag taggatacgc tgttaagaca
     1441 ggtttgacgt cttaccaacg attgaaagaa cttgaaattt caaaacaagc atggcaggat
     1501 agagcagact attatcaaat ttcttttggc ttaggtgata gaggaaaaga tatagaaaat
     1561 cagagcaagt ggtatgcctt tgccaaggaa gcaatcgaag aagaacaagc tctttatgta
     1621 aaggataatc tgctccattt tgccaatcca caaggaaaaa atgaacaggg agagacactg
     1681 gatacctata gtccagatgc taatacgctc tatgttagtc ctagttattt ggacaaggaa
     1741 aaggtcgtgg tagatgctga gaccaaacag aagttagccc atctccaaaa aggtgagttt
     1801 atcctcttgc tcccagaaca tttgcgctct cgagaagcag aacttaagaa agtttttgaa
     1861 gaaagattga gttattatgg aaaatctggt gaggaggcaa gtgctccttt ggattatgag
     1921 atgaaagcgc acgttagtta tctttcaatg ggagaaaagc ggtttgttta taataacggt
     1981 gagaatcccg tatccactca gtatttgact gatccgattt tagtggtatt cacgccgact
     2041 tctacaggtg atagttttat atccttatct agttggtcta tcaatgctgg aaaacaactc
     2101 tttatcaaag gatatgagag tgggctagaa ctcttgaaga aagttggaat ttatgagcaa
     2161 gtatcctatc ttaaagaagg aagaagtgtt tatctaactc gttataatga agttcaaact
     2221 gaaacagcaa ctttaatctt aggagctatt gtggggatag ctagttcctt attactattt
     2281 tattctgtca atcttctata tttcgagcaa ttccgccgag atatcttgat taaacgaatt
     2341 tcaggtttac gattttttga aacacatgct cagtatatgg ttagtcaatt tgccagtttt
     2401 gtatttggtg ctagtctctt tattttaagc agtcgagact tggtgattgg cttgctcact
     2461 ttattagtct ttctagctag tgcagttctg acgctttacc gtcaagcgca gaaagaatct
     2521 cgtgtttcta tgacaattat gaaaggaaaa taggatgatt gaactaaaga atatatctaa
     2581 aaaatttgga agccgtcagc tattttcaga tacaaatctt cattttgaag gtgggaaaat
     2641 ttatgcctta atcggtacaa gtggctgtgg taagacaaca ctcttgaata tgattggacg
     2701 attagagcca tatgacaaag ggcaaatcat ctatgatggc acttctctta aggacatcaa
     2761 gccttctatt ttctttagag attacttggg atacttattt caagattttg gcttaattga
     2821 aagccaaacc gtcaaagaga atctcaatct gggtttagtt ggtaaaaagt tgaaggaaaa
     2881 agagaaaatc tctttgatga aacaagctct aaaccgtgta aacctctctt atttggattt
     2941 gaagcaacct atatttgagt tatcaggagg agaagcacaa cgtgttgcat tagcgaagat
     3001 aattttaaag gatccacctt tgatcctcgc agatgaacca accgcttcct tagaccccaa
     3061 aaactctgag gaattacttt ccatcctaga atctttaaaa aatccgaatc ggaccattat
     3121 tattgcgacc cacaatcctc tgatttggga gcaagtggat caggtcattc gagttaccga
     3181 tttatcacat agatgatatg gtaagattca gttagaagaa agagtcacaa acacactttg
     3241 tggctttttt atttccataa aaatggtaaa atagtaggag tagaaatgga gttcgagaca
     3301 tgaaagtaat agatcaattt aaaaataaga aagttcttgt tttaggtttg gccaagtctg
     3361 gtgaatctgc agctcgtttg ttggataagc taggcgccat agtgacagta aatgacggga
     3421 aaccattcga ggacaatcca gctgcgcaaa gtttgctgga agaagggatc aaggtcatta
     3481 caggtggcca tcctttggaa ctcttggatg aagagttcgc cctcatggta aaaaatccag
     3541 gtatccccta cagcaatccc atgattgaaa aggctttggt caagggaatt ccagtcttga
     3601 ctgaggtgga attggcttat ttgatttcag aagcactgat tattggtatc acaggatcga
     3661 acggtaagac aaccacaacg actatgattg gggaagtttt gactgctgct gggcaacatg
     3721 gtcttttatc agggaatatc ggctatcctg ccagtcaggt tgctcaaata gcatcagata
     3781 aggacacgct tgttatggaa ctttcttctt tccaactcat gggtgttcaa gaattccatc
     3841 cagagattgc ggttattacc aacctcatgc caactcatat cgactaccat ggggcatttt
     3901 cggaatatgt agcagccaag tggaatatcc agaacaagat gacagcagct gatttccttg
     3961 tcttgaactt taatcaagac ttggcaaaag acttggcttc caagacagaa gccactgttg
     4021 taccattttc aacacttgaa aaggttgatg gagcttatct ggaagatggt caactctact
     4081 tccgtggtga agtagtcatg gcagcgaatg aaatcggtgt tccaggtagc cacaatgtgg
     4141 aaaatgccct tgcgactatt gctgtagcca agcttcgtgg tgtggacaat caaaccatca
     4201 aggaaactct ttcagccttc ggtggtgtca aacaccgtct ccagtttgtg gatgacatca
     4261 agggtgttaa attctataac gacagtaaat caactaatat cttggctact caaaaagcct
     4321 tgtcaggatt tgacaacagc aaggtcgtct tgattgcagg tggtttggac cgtggcaatg
     4381 agtttgacga attggtgcca gacattactg gactcaagaa gatggtcatc ctgggtcaat
     4441 ctgcagaacg tgtcaaacgg gcagcagaca aggctggtgt cgcttatgtg gaggcgacag
     4501 atattgcaga tgcgacccgc aaggcctatg agcttgcgac tcaaggagat gtggttcttc
     4561 ttagtcctgc aaatgccagc tgggatatgt atgctaactt tgaagtacgt ggcgacctct
     4621 ttatcgacac agtagcggag ttaaaagaat aatatgaaaa aaattgtctt tacaggtggg
     4681 gggacggttg gacacgttac cctcaatctt ttgttaatgc ccaagttcat cgaagatggt
     4741 tgggaagtcc actatatcgg ggacaagcgt ggtatcgaac accaagaaat ccttaagtca
     4801 ggtttggatg tcaccttcca ttctattgcg actggaaaat tgcgtcgcta tttctcttgg
     4861 caaaatatgc tggacgtctt caaagttggc tggggaatcg tccaatcgct ctttatcatg
     4921 ttgcgacttc gtccacagac ccttttttca aaggggggct ttgtctcagt accgcctgtt
     4981 atcgcagcgc gtgtgtcagg agtgcctgtc tttattcacg aatctgacct gtctatgggc
     5041 ttggccaata aaatcgccta taaatttgcg actaagatgt attcaacctt tgagcaagct
     5101 tcgagtttgt ctaaggttga gcatgtggga gcagtgacca aggtttcaga tcaaaaaaat
     5161 ccagaaccag atgaattggt ggatattcaa acccacttta atcataaatt gccgactgta
     5221 ttgtttgttg gcggttctgc aggtgctcgt gtctttaacc aattggtgac agaccataag
     5281 aaagaactaa cagagcgcta caatattatc aatctaactg gagattctag cctgaatgag
     5341 ttgagccaaa atctttttcg tgttgactat gtgaccgatc tctatcaacc cttgatggaa
     5401 ttggctgata ttgttgtgac acgaggtggt gccaatacga tttttgagct cttggcgata
     5461 gcaaaattgc atgtcattgt gccgcttggt cgtgaagcta gtcgtggtga ccagattgaa
     5521 aatgcagctt actttgtaaa aaaaggctat gcagaagacc ttcaagaaag cgatttgacc
     5581 ttggatagtt tggaagagaa gctttctcac ttactaagtc acaaggaaga ttaccaagct
     5641 aagatgaaag cttctaagga attgaaatct ctagcagatt tttatcaatt gttgaaaaaa
     5701 gatttatcat aaggaaagta aatgtcaaaa gataagaaaa atgaggacaa agaaatcctc
     5761 gaagaattga aagagttatc agaatggcag aaacgaaacc aagaatatct aaaaaagaag
     5821 gctgaagaag aggcggctct agctgaggag aaggaaaagg aaagacaagc tcgaatggga
     5881 gaagaatctg agaagtcaga ggataaacag gaccaggaga gtgaaacaga ccaggaagat
     5941 tcagaatcag ctaaggaaga gtctgaagaa aaagtaacat cctcagaggc tgacaaagag
     6001 aaagaagaga aagaagaacc agagtctaaa gagaaggagg aacaggataa aaagctttct
     6061 aaaaaggcta caaaggaaaa accagccaaa gcaaagattc ctggtatcca tatcttgcga
     6121 gccttcacga ttttatttcc aagtctgctt ttattgtttg tctctgccta cttgctcagt
     6181 ccttatgcga ccatgaaaga tattcgtgtt gagggaacgg tgcaaactac agctgatgat
     6241 attcgacagg cttcaggcat tcaggattcg gattatacga ttaaccttct gctagacaag
     6301 gcaaaatatg aaaagcagat taagtctaac tattgggttg aatcagctca acttgtctat
     6361 caatttccaa ctaagttcac tattaaggtc aaggaatatg atattgtggc ctactatatt
     6421 tctggtgaaa atcattatcc tattctttcc agtggtcagc ttgagactag ttctgtgagt
     6481 ctgaacagtt taccagaaac ttatttatca gttctcttta atgatagtga acaaatcaag
     6541 gtttttgtct cagaacttgc tcaaattagc ccagaactca aggcggctat ccaaaaggtg
     6601 gaattagccc caagcaaggt gacatccgat ttaattcgat tgaccatgaa tgattcggac
     6661 gaagtcttgg ttcctctatc tgaaatgagt aagaaactgc catattacag taagattaag
     6721 cctcaattgt cagaaccgag tgtggtcgac atggaagctg gaatctacag ctacactgtg
     6781 gcggataaat taattatgga ggctgaggaa aaagccaaac aagaggccaa ggaagctgag
     6841 aaaaaacagg aagaagaaca gaaacgttta gaagaagaac agaaaaaaca agaggaagag
     6901 agcaatcgaa accaaacgac ccagcgctca tcgcgtcgct aggtttacct tttctcttat
     6961 agttctttag tgactaagtt tttacttgac aagtgctagt agaaataata gaatagtaaa
     7021 aaacctttaa agcagtccag agaggcagct aaggttagac ggtgaaaggg tggagactac
     7081 ccatttttcg tggaaccttg ctgttggcag gttccttttt tcgtggcttc tgttggccag
     7141 actctctcac tagtaaaggt aaaaggagaa acctatgcga gaacatcgtc caatcattgc
     7201 tcttgatttt cctagttttg aggcggtcaa ggaattttta gctcttttcc cagcagaaga
     7261 aagcctttat ctcaaggtag ggatggagct ttattacgca gcggggcctg agattgtgtc
     7321 ctacttaaaa ggtttgggtc atagtgtctt tttggatctc aaacttcatg acattcctaa
     7381 tacagtcaag tcagccatga aggtcttgtc tcagcttggt gtcgatatga ccaatgttca
     7441 tgcggctggt ggtgtagaga tgatgaaggc tgcgcgtgaa ggtcttggaa gtcaagcaaa
     7501 attgatcgct gtaacgcagc tgacatcaac atcagaagcc cagatgcagg agtttcaaaa
     7561 tatccaaaca agcctacaag agtctgtgat ccactatgcc aagaagacag ctgaagcagg
     7621 cttggatggt gtcgtttgct cggcacagga agttcaactt atcaagcagg ccaccaatcc
     7681 agattttatc tgtctgacac cagggattcg cccacaggga gctgctgttg gagaccaaaa
     7741 acgcgtcatg acgccagcag atgcttatca aattggtagt gactatatcg tagtgggacg
     7801 tcccattacc caagctgagg atcctgttgc agcttatcat gccatcaagg atgaatggac
     7861 acaggactgg aattaaagaa ctagattaga aaaataaaag gagaatacca tgacacttgc
     7921 taaagatatc gctagccacc tcttgaaaat ccaagccgtt tacctcaaac cagaggaacc
     7981 cttcacttgg gcgtctggta tcaagtcacc gatttacact gataatcgtg tgacactagc
     8041 ctatccagaa actcgtaccc taattgaaaa tggttttgtg gaagctatca aagaagcctt
     8101 tcctgaagta gaagtgattg caggaactgc aacagcaggg attccacacg gagccattat
     8161 tgctgataag atggacttgc cttttgccta catccgtagc aaaccaaaag accacggagc
     8221 tggtaatcaa atcgaaggtc gcgtagctca aggtcaaaaa atggtagtgg ttgaagacct
     8281 tatttcaacg ggtggttcag ttcttgaagc tgtagcagca gccaagcgag aaggagcaga
     8341 tgtacttgga gttgtagcga ttttcagcta ccaattgcca aaagcagata agaactttgc
     8401 agatgctggt gttaaacttg tgacgctttc aaactatagc gagcttatcc atctagccca
     8461 agaagaaggt tacatcacgc cagagggcct tgatcttcta aaacgcttta aagaagacca
     8521 agaaaattgg caagaaggtt aggtcagtaa gataaagaga gacgaggcta ccgagtctct
     8581 tttaccattt tatttaaaat atgataatat tttaaataaa ataattgaca acgctttctt
     8641 ttattgatat aatgaaaatg taatatgtat caaattgatc aatcaactat cttgtttatc
     8701 acttcttaag aggacgatgt catgaaaaga agaaaaatat attccttttt tgcgtagtta
     8761 caattgcatc tagtttgttt ctccctacag ttttagctag acagattgga aattatgatt
     8821 taacgttgcc gcgttggggt tcggatacaa ctagtgagct tgagaaagaa aacgcctctg
     8881 ctggaattaa taatagtgac agcactggtg gcggtaaaag gttaaatacc tctattcgta
     8941 gcgcctatag tgggtcagat attaccccgg tatattcatt ggggtctggc tctaggattg
     9001 tcatgtacta taatggaggt ggtgacaatt atattggttc tggtactaga ttagctatgg
     9061 cgccacaatt tggaaatcat gtaagaattc atacttcagg ttcttggagt ccagattctt
     9121 attaacttac ttgtcagagt aagccttaaa gatggttgat tgtgggtgta gcatgaaaaa
     9181 agaatgctac accctatttt tattataagg aggagtaagg atggaatttt tcatttgtaa
     9241 tcttgtacga gtcgttcaat cacctcggtt ttatatgtct ttatttttga cccttctttg
     9301 catgagttta ggaaatttcc ttgctttcaa tggtatttat aaaattgaag gtttatcgat
     9361 tttttttgcc gcttcttcta ttcgaggatt ttcaccgatt agcctagtag ctgcacttat
     9421 ctgtacactg ccctattcta gtcagataat agaggatgct gagagtcatt ttctaacagc
     9481 acaattgtgc cgaatttcta aaaagaggta tctagctatt gtaggtagta ctgcaattat
     9541 ttcttctttt ctagtctttt ttctccccta tttattatta ttaggaatta atcttttagt
     9601 gactccttat caggaaattt atattggaga ttatagtggt gccttaaaag aattatttga
     9661 ttctaatcag tttctctata gtcttgtgac gactctctgg tatggagttt ggggcgctgt
     9721 gttctctatt tttggactag ctagtgcttt gctagtgaag aaaaaattag gagctatttt
     9781 catcccagtt gcctatatga tggttggtgg tattttatgg gctattttag ggctatctta
     9841 cttagaacct gtgacaacgc tagctttggg atatcagaaa gatatcagtc tttccttagt
     9901 tagtgggcat cttgctttta ttttatttgt tagttgtttg gttgtttatg gtacattttt
     9961 tctacattca gaggactatg tataatgaaa caatttgttc aattttataa aaaagatttc
    10021 ttagcagtat tggtttattt tatattactg ctatcctgtg ttttatctag tacagtatat
    10081 ttattgcgct gtcgccaata ttcaatccat ccaaatgtat tagaatggat tttagtttta
    10141 cttcaagata tgacgactgg agtatattgc tttccgttca catatatatt gttctttttt
    10201 tatttgatga ataactattt taataggttg gagtgtcgca ttcgtctgaa atcaattaag
    10261 cactttacca gttttagttt caaattagca gctcttagta cggggatttg gacggcgact
    10321 ttatttttat tgatttttct aattgcattt agtaatggtt ttagcttctc tttggagata
    10381 aaggaggttg attttttaag agaattttat ggtataagta ttgcaaacaa tgctagtttc
    10441 tttataggat tttttttctc ttatatagca tactatttct ttttatcctt acttactatt
    10501 agcagttttt cttggtttaa aaaatcaaac atgagcttag tatttctgtt tactttttta
    10561 tttgtagaat ccttattctg gatttatcag ttgaacaatg ggataattgg attattgcca
    10621 atttttcagt atatggtaaa ttccaatccg tatgcattga tttattggct tacattacta
    10681 tctatcataa ttccattgac tgtattttct gttcatagaa actggaggag agtgtaaaag
    10741 ttggaaatgg gaaagttaag tagtcacatg tggaggttga atcagataat ctataccaag
    10801 tacttttggg gttatgttct tttttggata ttgatttgtt taggattatg gtattggtta
    10861 gaaggaaatg atagacttgt tatagaaatt ttaaaagggc ctaatctgag tcaaaactct
    10921 tttttagtct tatctatatg gttgcttcat tggtttatta ttcatacatt ttttctagca
    10981 gttgtatatc gtagaagagc atccgatttc tttatggaag tgattcgatt ttcttctatt
    11041 aagctctgga ttaggtatca gatttggacc tgttttcttt atggactcat tttaatcatg
    11101 gtaaaagttc tagtgattca atttatgtta cagttagcaa actgggatat aggagttttg
    11161 tttatagttg attctttgaa tgcttgtgtg ctatccttgc tttgctttat gttatacgca
    11221 ctaggagcga atgtacaaat gaactttgct tgcgttagtt tctttttact catgattgtg
    11281 tttggtggtc tatttgtagg aaatcgaact aattatctat tttatatttt gaatcgaggg
    11341 aatggagata taggacgaga tttatttctt cagttgctat ttttagtctt tctttttaaa
    11401 agcattttct atttcactcg tcaaaagagg aggtttatag aatgaatgaa ataattacat
    11461 taaaaaatat tgagttgaaa ttaaaaaaaa catgtgtttt tcaaaacctt aattttagtt
    11521 gtaaacaggg ggaaattata ggaattactg gtgcgaatgg ctcaggtaaa agtgtattgt
    11581 ttaaattaat agctggttta tatagtccgt cttatggaga agtgttaatc aatggggaaa
    11641 atattgttcc tgagagaaaa attccagcta atttgggagc tttgattgaa gaacctggtt
    11701 ttataaatta ttatagtggc tttaagaatt tacaatattt ggcaagcata cgaggagtag
    11761 ttggtaatca ggaaatcaat gatacactga aaatagttgg tctatatgag caaaaagacc
    11821 agaaagttaa aacttattcg ctaggtatga ggaaaaagct agggattgct caagcaatta
    11881 tggagaatcc ctctattctt ttactagatg aacctatgaa tgccttggat aaatcaagtg
    11941 tagaaaatat gagaacattg tttagaaagc tctctagtga aaaagggaca acaattttga
    12001 ttgctagtca tagtgaagag gatattcgta tcttatgtga taaagtatat gcaatagaag
    12061 ataaagtatg tacactgtgt tcagattgaa catcttagat agactcagga tgttataggt
    12121 aaaatcttaa aaagggattg gagcttaaaa tccagtccct tttaagagtt aatggccacc
    12181 ttcaacaacc aggtcatctg ctttagcagc gtcaccgtag gttgggtgaa gtgttttttc
    12241 ataggccttg tggaagaagt tttccttgcc taatttttca atatctttat tgatgaagtc
    12301 tagcaattct tggttgcctt tttgaactgc tgccgcaatg gtatcgggat caccgaggga
    12361 agtaattcct acttcaaatc ctttattttc aagtgcccaa gctagaactt ccgtattgtc
    12421 agttgaaaag gcatctccac gtccgtcaag aagagcttgg taagagtcac tgtattggtc
    12481 gtatttttgg agtttgattt ctggatgatt cttttcaaaa taagtctcag cagtcgttcc
    12541 ttttgtgaca attaaggttt taccttcaag ttgtttgacg tctgtaatga gaccagtctt
    12601 aggtgatacg acacccagag aaactttcat atatggaagg gcaaaatcaa cttgtttctt
    12661 acgttcgtca gttactgtaa agttagcaag agtaatatct accttgtttg aaatcaagta
    12721 ttccgcacgg ttggcagcat cgactgaaat gtatttaacc ttgacaccaa ggtcttgagc
    12781 tagttggttc cctagttcaa tatcgtagcg tagccttggt aagaaccatc attgtcaacg
    12841 tagccaaacg gttttttatc tccaaacacg gcgattcgca gttcaccgct ttttttgatt
    12901 tcatcgatag tgcgagcttt ggcagttgtt tttccagagg atgaaccagc gtttccacct
    12961 gagctacaag cagtgataaa gataagggca aaggcaagtg ctaaaacagt taagagtggt
    13021 ttgaatagtt tcataagaat ctcctttata gatatgagcc gaattggcta aagtcaaaga
    13081 cgtttaaaaa ttcctgggct cgtttggttt gcggattggt aaagaaggct tgagctgttc
    13141 cttcttcagc gattttccct tggtcgagga agataatccg gtcagtaatg gcttgggcaa
    13201 actgcatttc gtgggttact aaaatcatgg tacggccttc ttgggccaaa tcattgataa
    13261 gttccagcac ctcacgcacc atttctggat ccagcgaagc agtcacctcg tcaaaaagga
    13321 tgatttctgg atgcattagg agggcacggg caattgcaac acgttgcttc tgtccaccag
    13381 ataattgacg ggcaaagcaa agctatgttg tttatccagc aaatcgacac gatctagtaa
    13441 ttgcaaagct tcttccgtta cttctttctt gtcccttcct tgagttttga tagggcctag
    13501 gatgaggttt tgtaagacat ccagatgggg aaagagttca taactttgaa agaccatgcc
    13561 aatcttttgg cgaactaggt gaaaatcttt tttattttca acgatagact gaccatccag
    13621 aaaaatatct ccaccttgaa tactttctaa gccgttgagg caacgaagga gggtactttt
    13681 cccacaacca gatggcccca ggatgacaac aacttccctt ttttgatttc tagagaaagt
    13741 ccttggagga tgggattgtc tccgaaggat ttttttagtt ccttgatttc taagatagtt
    13801 tcagacattt agtttctcca atgtttttct aagtgagtgg atagtttgga aatagggtag
    13861 caaactgcga aatataagac tagaatggtt ccataaatcc aaaatgaagc agttgggatg
    13921 gtcaggcgat tgctatcgat gatttgttgt ccaactttgg tcacttccac aaccccaatc
    13981 aaaacaacta atgaagtggt tttaatcatc cgagtgacaa gattgatagc ctgcggtagc
    14041 agtcttctta agacttgtgg gatgatgatg tggtagtaaa gttgaacatt agtcaagtcg
    14101 agtgcctatc cactttcaaa ctgatgttta gggagagaag tgatagctcc acgtaccaag
    14161 tctcccattt cagctgttcc ccagagggta aaaatgataa tagctgaagt ctcacctgag
    14221 atattgatat taaagtttcg agccaagcca aagtaaacga tgaagagtag caccagctgg
    14281 ggcatgatac ggataaattc cagatacaat cgtgttaaaa atcgtatgat tctagaatgg
    14341 gaggtcatga tgattcccat gactgttccg aacatcatgg ataagaggac agacaggatg
    14401 gatatcccaa tcgtaacgcc caacccctgt aagattctca ggagattatt tccttgaaag
    14461 agtacttgga ttcccgaatc ctgcatggcg ggtcctcctt tctatccagc taaagaccag
    14521 tgagatgggt agcagcatga tcagataagc aactaccaac atagctagcg caatgtctgt
    14581 ctcatagtag agaccaatca aatccttggc gacgtacatg aggtcggcca aagccactgc
    14641 tgagaaaaca gaggtttcct tgataaggaa aatgacattg gcactaaagg aggggagttc
    14701 caccgctgtt gcttgcggaa gaaccacata gcgaaagacc tgtagaggtg tcagaccaat
    14761 agcgaggcca atctcctgct gggtttgact gatggcttcc agcccacttc ggaaagattc
    14821 tgccatatag gagcctccta aaaagacaag cccaagcgtt gcacagactt ctgaagatag
    14881 gacaatcccg attcggggaa gaccgaagta gagaaagaag agttgaatca aaaggggcgt
    14941 attacgtgac aattcaatgt aggttgtcgc tacttgcgcc aaaacaggga ttcgataatg
    15001 tcggatgata ctaacgatta aaccgagcag aaaggatccc aaaattcccc aaactgcaat
    15061 atgcaaggtc agaaagaatg ccttttgata tagtggtaga tattgttcaa caatggacca
    15121 atccaaaaat agaacctccc atctagaaat aatacagtta ttgtagcact taaaatcttc
    15181 tttggataat atctattttt tattgccgtt ataaggattt tttaccatag acataaaatt
    15241 tctgaaattt ccaaacaaaa tatttgaaaa gttttgaaaa aaga
//
LOCUS       DAVMCG010000044        14066 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVMCG010000044 DAVMCG010000000
VERSION     DAVMCG010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14066
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.045"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(15..1219)
                     /locus_tag="VYP66_001724"
                     /pseudo
     CDS             complement(15..1219)
                     /locus_tag="VYP66_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            1462..1731
                     /locus_tag="VYP66_001725"
                     /pseudo
     CDS             1462..1731
                     /locus_tag="VYP66_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            1862..2213
                     /locus_tag="VYP66_001726"
                     /pseudo
     CDS             1862..2213
                     /locus_tag="VYP66_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2489..3795
                     /locus_tag="VYP66_001727"
                     /pseudo
     CDS             2489..3795
                     /locus_tag="VYP66_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(3835..4845)
                     /gene="tsaD"
                     /locus_tag="VYP66_001728"
     CDS             complement(3835..4845)
                     /gene="tsaD"
                     /locus_tag="VYP66_001728"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1851234.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(4835..5272)
                     /gene="rimI"
                     /locus_tag="VYP66_001729"
     CDS             complement(4835..5272)
                     /gene="rimI"
                     /locus_tag="VYP66_001729"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1851235.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(5269..5952)
                     /gene="tsaB"
                     /locus_tag="VYP66_001730"
     CDS             complement(5269..5952)
                     /gene="tsaB"
                     /locus_tag="VYP66_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1851236.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            6130..6315
                     /gene="cibA"
                     /locus_tag="VYP66_001731"
     CDS             6130..6315
                     /gene="cibA"
                     /locus_tag="VYP66_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1851237.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLDPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            6318..6470
                     /gene="cibB"
                     /locus_tag="VYP66_001732"
     CDS             6318..6470
                     /gene="cibB"
                     /locus_tag="VYP66_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1851238.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            7288..7521
                     /locus_tag="VYP66_001733"
     CDS             7288..7521
                     /locus_tag="VYP66_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1851239.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            7523..9202
                     /locus_tag="VYP66_001734"
     CDS             7523..9202
                     /locus_tag="VYP66_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1851240.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGKEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(9397..11310)
                     /gene="mnmG"
                     /locus_tag="VYP66_001735"
     CDS             complement(9397..11310)
                     /gene="mnmG"
                     /locus_tag="VYP66_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1851241.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMINEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENTEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEELDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(11320..11775)
                     /locus_tag="VYP66_001736"
     CDS             complement(11320..11775)
                     /locus_tag="VYP66_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1851242.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(11916..13037)
                     /gene="mnmA"
                     /locus_tag="VYP66_001737"
     CDS             complement(11916..13037)
                     /gene="mnmA"
                     /locus_tag="VYP66_001737"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1851243.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(13438..>14066)
                     /gene="cbpA"
                     /locus_tag="VYP66_001738"
     CDS             complement(13438..>14066)
                     /gene="cbpA"
                     /locus_tag="VYP66_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HEV1851244.1"
                     /translation="YFYNTDGSMATGWLQNNGSWYYLNANGSMVTGWLQNNGSWYYLN
                     ANGSMATGWLQNNGSWYYLNANGAMATGWLQNNDSWYYLNASGAMATGWAKVNGSWYY
                     LNANGAMATGWLQYNGSWYYLNANGAMATGWVKVNGSWYYLNANGSMATGWVKDGDTW
                     YYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
BASE COUNT         4054 a         3247 c         2674 g         4091 t
ORIGIN      
        1 cttgatctat attcctatcc atgactactc ttctctaata attcatcata tactctcatg
       61 gtttctacaa acattttttg cacagaaaaa tgttttctta tttttgattt actattctca
      121 cctatatatt tcaaatactc agaatcattg agtaaaaaat tagcacaagc acacactccc
      181 tcaacatctt ccttctcaaa taaaaatcca tcaaccctat gttcaataat ttcacttaac
      241 ccgccaacat tactagctaa aaccggagtt ccttgtgaca ttgactctaa aacacacata
      301 ggtattcctt ctgtatcaga aggaatatac aataaatccg atatttggta aactatagta
      361 ctggatagat ttcaccaagt aacctgaaat tatctctaca tttcaaatag caaatttttt
      421 ctttcaaagc agcccacata ctaccatttc cagccataat aaaaatcaca tcttctctga
      481 ctaaaaataa tttttctgca aattcaagga atctatccgg ccttttttct ggatccaacc
      541 ttccaacata acaaatgatt tttttgttat ttggaataca aaattctttt ttaaagtctt
      601 gaacacctac tacatctaaa tcgctatttg atacattaat tccgttattt attgcaacta
      661 tcttcttatt ttttattata ctctccaatc tttttttcat agtttcagat acacaaataa
      721 aagcatctcc catagaatat gtccaaaaat caaaataagt caagaatttc ttttttaagt
      781 tatattcaac ccatccatgg catgttatca ctgtcttaac ctttccaaat ccattcttgt
      841 caagtttttt taacatatat aaaaaataat tagttgagta gccatgacag tgtataagtt
      901 ggatttttaa taattttaaa atatttttaa cgtgtaaggc agtttcaaaa ttatttgaac
      961 attgagtaca atcaacatag gcaatatcta aatttttata atcatcaata acctttgaat
     1021 ctctagatac gattatcaaa ataggatata gagacatcct tctgatctgc tttttacaaa
     1081 gtccaattat atgcggatct atacctccac aatgtccatt attataccta actataatat
     1141 gagccgaaaa cactatatcc ttaatgtctc catatccatc agggatatta atatttattt
     1201 ttccacaact atattgcatt gtaaccatct ccttaaacga cgcattatga tatttgatag
     1261 agaaattttt atgaataact caataatttt atagtaaatc atgcttatat ctcaaagata
     1321 cctattttct cttgtctcga ccttctccaa agaattgcta taatactatt acaaatacat
     1381 ctgcactaca cttcaaattt tagcactgta taaaaacgtt tcaacacact aactttaaga
     1441 aaacttccac tattaattga aaaagttgat agagataaat taaagatcta tattgaaact
     1501 catcccgatg cttatttgac tgaaatagct gctgaattca actgtcctcc aacaactatt
     1561 cattacgctc taaaggctat gggatatagt ctaaaaaaga gccgtaccta ctgcgaacaa
     1621 gacccagaaa aagtaaatcg gttccttaaa gaattgaatc acttaagcta cctgactcct
     1681 atttatattt atgagacagg ggttgagacc tatttttatc tcgaatatga ttgatccttg
     1741 agcaggcagt tagtctctct ggaagaagat ataattattt gaattaagat cgagacaacg
     1801 cacaccagag attgcgatac tgttatagaa gtactaatac ccttttttgt ttcaatatac
     1861 tatggctccg atgacctata aagatacgat gacgagtgac tttttcgaag cttgcttcca
     1921 aaaattctta ctacctactt tagatacacc atcccttatc attatggacc atgcaaggtt
     1981 tcacagaatg aacatgtgta aggagcaggg catagactgt taccacttcc tacctattca
     2041 cccgagtata atcccattga gaaaatatgg gcttacatca aaaacatctc agaataatat
     2101 tgtcaaatta cgatgctttt cttgaggcac ttttgtccta ttcttgtttc agccgactat
     2161 actccgttat tgggcagcta cggaacagtc gatgggacga tggggggaca taaaaaaatc
     2221 ctccagtttt gttttttata acagtatact ggagaattga caatctcggt agatacctcg
     2281 ttatagcgcg gttacttatt aggcagttac aaaacaactg tgaacagaaa acattccaga
     2341 gtcagacaag actttggaat gctttggctc tataatttct gtagtgggta atcccacccc
     2401 aggaattata gggtcgtttc ttgtagaaaa aaagccccat atgacctata atgaaaagcg
     2461 tctaaccaac tcattagaaa gggttcatat ggaacaactt aagaatacca cagatttgct
     2521 cggattggaa gacaaaaata tcaaaatctt gtctgttctg aaataccaaa cccatctagt
     2581 cgttcaggca aagttggatt cccccgctcc tccttgtcct cattgtcaag ggaagatgat
     2641 caaatacgac ttccagaaag cctctaaaat tccgcttctc gactgtcagg gtttacccac
     2701 ggtactgcat ctcaaaaagc gccgctttca gtgcaagaat tgccttaagg tggtcgtttc
     2761 tcaaacatcc attgtcaaga aaaattgcca gatttccaac atggtgagac aaaaaatcgc
     2821 tcagctcctc cttgaaaagc agtctatgac tgagattgcc cacagattgg cggtctcaac
     2881 ttccaccgtc atccgaaaac tgagggaatt taagtttgaa accgattgga ccaagttgcc
     2941 aaaagttatg agttgggatg agtatagctt caaaaagagc aaaatgagct tcattgccca
     3001 agattttgag tccaaatcca tcctcgcaat tttagacggg cgaactcatg cggtgattcg
     3061 aaaccatttc caacgctatc agagagaggt tcgggagctg gtcgaggtca tcaccatgga
     3121 catgtacagc ccttattatc ggctcgctaa gcaactcttt ccaaaggcga agattgttct
     3181 tgaccgcttc cacattgtcc aacatctgag ccgagctatg aaccgagtac gaatccaaat
     3241 catgaaccaa tttgaccgaa aatccttgga gtatcgggcg ctcaagcgct tttggaaccc
     3301 tcgctttttc gtttctaggc tcgggctaaa tcagtccact ggactgattt actacaccag
     3361 tatagcttca agctctgtca gaaacgattc tatcagccca cgtttcgaat gcacttaacc
     3421 catcgggaag tacgagataa gctgctttct tactctgagg gattacaggt tcactacgaa
     3481 ctctatcaac tcctgctctt tcattttcaa gagaagaatg ccgaccattt ctttggattg
     3541 attgagcaag aactgccaac ggttcatccg ctttttcaaa cggtcttttg gactttttta
     3601 agggatagag ataagattat caacgcactt aagctgcctt attccaacgc taaacttgaa
     3661 gcgaccaata atttgattaa gattatcaag cgcaaagcct ttggtttccg gaactttaac
     3721 aattttaaaa aacggatttt gatgactttg aacatcaaaa aagagagtac gaatttcgta
     3781 ctctccagat tgtagctttt cgcctaccca ctacacttga caaagagcca ctctttattc
     3841 catggtatca aaggcaagac ttggtttggc attgaggtcc cagcctgcga agttttcttt
     3901 gttccactcg ctgacgctgg cataggcaat catacctgca ttgtctccgc agagtcgcag
     3961 aggggggatg ataaccttga catctgtgat ttcggctgct aggcgttctc tgagaccttt
     4021 attggctgcc acaccacctg ccacaaccag ggttttaaca ggatatttct ccaaagcctt
     4081 cttggttttt gccatgagaa tgtccataac tgctgcttgg aaggaagcac acaaatcttc
     4141 tgtagacagg ctttctccct tttgctcggc attgtgataa agattgataa aggcagattt
     4201 caaacctgag aaggagaact ccagattatc ttccttaatc atggcacggg ggaaatcata
     4261 aatatcctgc ccctgatgag ccagctcgtc aatctcacga cctgcaggat aggtcaagcc
     4321 catgacacgg ccgaccttat cataagcctc accaaccgca tcatcacggg tttccccaac
     4381 aatcttataa tctcctgcct ccgaaacata aaccaactct gtgtgtccgc cgctgaccaa
     4441 gagggctagc aagggaaact ccaaaggctc cacactctga gctgccatga ggtgcccagc
     4501 catgtgatta acaggaatca gtggaagtcc gtgagcccaa gcaaaggcct tggcagctga
     4561 caaaccaact agcaaggctc cgaccaagcc tggtccgtag gtaaccgcaa cagctgtcac
     4621 gtcctcttcg gtaatccctg cttctgccaa tgcctcctcg atacaggctg taatgacctc
     4681 gacatggtga cgactggcta cttcgggcac tacgccacca aaacgtttgt gactctcaat
     4741 ttgactagca atgacattgg acaagagctc atcgtcgttt ttcaagacgg cgacactggt
     4801 ctcatcacag gatgtctcaa atgctaaaat atatctatcc ttcatctatt tctctcttca
     4861 tgataatggc gtcctcgact gggtcatggt agtaggcctt tcgctcagcg atgaccgcca
     4921 ttttttcttt cttgtaaaat gcttgcgctc gttgatttga ctttctgact tcgaggaaaa
     4981 tctccttatc tgtcggcaat tgagcaaaca aggctgacgc aattccctga ccctgatagg
     5041 ctcctttgac agcgatttgc aggacttctg cttcaaaaag attctcctgc acagctagaa
     5101 atccaatcac ttctgcccca tcataagcca atgcatacca agtctggtct tgggacagat
     5161 ctgcttggat ttgctccaga gtccaaggac tgactaggta aacagctgcc ataacagcgt
     5221 agatggcttg agctaggtca ggctgttgtt gaattcgctt gatttctatc ataggcgttt
     5281 aatgtaggac tcaccagact cggtatggtt cttgagccag ttttcctctg cctcaacacg
     5341 tttgaggtaa tttggcacaa aatcatgcaa ggagtctgct tccttgtccc aggccaaaag
     5401 agctagatta gctgcattgg gcaatgtttc tttgtaatca gtccttggca agtgtttttg
     5461 aatctgctca acaaaggggc caacttctcc gacaaaggtt acctgactag cgcccttgat
     5521 tagctcaatg actcgctcaa aaggcagatg tgcttctgcc atgacaggtt tggcattttc
     5581 ataaaatcct gcataaacat tattgcgacg cgcatccatc aaggggacaa acaaaccttc
     5641 ttgttggtag ggcaccagag ccaagagact cgacatacca accaactcga tattcagagt
     5701 ataagccaga gttttggcag tggctaccgc gattcgcaag cctgtgtagc tacctggccc
     5761 ttccgccacc acgattcggt ccaaatcctt gggcgtccag tccaaactct ccatcaaaaa
     5821 atcaatggct ggcatgaggg taatactgtg atttttcttg atattaatcg tcgtctcagc
     5881 aagaacctgc ttgtcctcta aaatagccag agaaagagcc ttgctggacg tatcaaaagc
     5941 taatactttc ataacacatt cctatctttt tgtctgctta ctattatact acaaaagctg
     6001 gcacatggga attttctttg cccccagaca agagtgccct cacttaacta aaaataatta
     6061 aaaaaaatgc tcacttttcc ttttcttttc cgaatataaa agtgaacaag aaaaaaggag
     6121 gaaagttcaa tgacaaattt tgacattctt gacaatcaat ttttatcctt atctgaaaat
     6181 gaattatcag atattgatgg cggtctcgat cccttggtta tctttggagt agcagtatct
     6241 tggaaggcta ttgcaggtgg aacagcactt ataggttctg gtttggcagc tggttatttt
     6301 ttaggaggag attaactatg atgaaagatt tgaacaacta tcgtgaaatt tctaataagg
     6361 aattgcaaga aatcaagggt ggctttggtg taggtgttgg tatcgcttta tttatggcag
     6421 gttataccat tggaaaagac cttcgtaaaa agtttggtaa gtcatgctag ataagaaaca
     6481 catttttaga aggataaatt ttattgtctt catctcttac agtttgctca gcattctcaa
     6541 tgatttgaac attactacta tccctttacc attcgattta tctgtttgta ttgttttatt
     6601 tttatgcttc aactctattt ttgagcagaa caatgactcc cataaaaata ataagctttg
     6661 aaaattccat tgtcatgtca tgttagaaaa atgcaaagac cacctcatct tgatagatgg
     6721 ggtggaattt tcgtgtcgta aatctactat ctctacatcc ccaaacaaaa aaccccagca
     6781 taagcagggc atctaagcat ttaatccaaa gtaaaataca aaccaaacga cataggtcac
     6841 gaggaggaga aaaagcgagt agagagtcac aaaggtaatt ttccacaaga acttggtttg
     6901 tcatcgttcc agtttggcaa atagaagatt tcctccataa acgcaagcaa caaaaacgat
     6961 aaaagctaac aaacgaactc cgatagcaaa agcaaataag ttatacatag ggcaacctcc
     7021 ttgacttaaa atctatatgg aattatgaca agcaataaat ttcacttccg ttatcaacat
     7081 aatatatttt ccttgttttt gcaaacgctt acaaaagaaa tcgtccccta actttctcgt
     7141 ttccgtcttt tactaatttt tcattttgtg gtataattga aataattgta acgaatcaag
     7201 gtcaatctag acacaaaatg gaatgaaatc aagcaaatat ctgctaaaag tttggaataa
     7261 gctgacctgt aaatagaaag gaactatatg atttacaaag ttttttatca agaaacaaaa
     7321 gaacgtagcc cacgccgtga aacaacacgc gcgctttacc tagacatcga tgccagctca
     7381 gaacttgagg gccgtatcac tgctcgccaa cttgtcgaag aaaatcgccc agagtacaat
     7441 atcgaatata tcgaactctt gtctgacaaa ttgctcgatt acgaaaaaga aactggcgcc
     7501 ttcgaaatta cggagttcta atatggccta cactcttaaa cctgaagaag tcggcgtttt
     7561 tgccatcggt ggtctaggag aaatcgggaa aaacacttac ggaattgaat accaagacga
     7621 gattatcatc gtcgatgctg ggattaaatt cccagaagat gacttgcttg gtatcgacta
     7681 tgtcattcct gactactctt acatcgtaga caatatcgac cgcgtcaagg ctgttttaat
     7741 cacacacgga cacgaggacc acattggtgg gattccgttc ctactcaagc aagcaaatgt
     7801 ccctatttat gctggaccgc ttgccttggc tttgatccgt gggaaactcg aagaacacgg
     7861 cctcttgcgc aacgccaaac tttacgaaat caaccacaac accgagttga cctttaaaaa
     7921 tctcaaggca actttcttta gaacgactca ctctattcca gagcctttgg ggattgtcat
     7981 tcatactcct caagggaaaa tcgtctgtac gggtgacttt aagttcgact ttactccagt
     8041 tggagaacct gcggacttgc atcgtatggc tgcgcttggt aaagaaggcg tgctctgtct
     8101 cctgtctgac tcgacaaatg cggaagtacc aacctttacc aactctgaaa aagtcgttgg
     8161 tcagtccatt atgaagatta tccaaggtat tgaaggacgt atcatctttg catcctttgc
     8221 ctcaaatatc ttccgtctcc agcaggcaac agaagctgct gttaagactg gacgcaagat
     8281 tgcggtcttt ggtcgttcta tggaaaaggc cattgtcaac ggaatcgatc ttggctacat
     8341 caaagctcct aagggaacct ttatcgagcc aaatgaaatc aaagattatc ctgcaggaga
     8401 agttcttatc ctctgtacag gtagtcaggg tgagcctatg gcagccctct ctcgtatcgc
     8461 caacggaacc caccgtcaag tacaattaca accaggtgat accgttatct tctcttctag
     8521 tcccatccct ggaaacacta ctagcgtcaa caagctgatt aacatcattt ctgaagctgg
     8581 tgtcgaagtt atccacggta aagtgaacaa tatccataca tctggacacg gtggccagca
     8641 agagcaaaaa ctcatgctct gcttgattaa gccaaaatac ttcatgcctg tccacggtga
     8701 ataccgcatg caaaaagtcc acgctggact agcagtggat actggtgttg agaaggacaa
     8761 tatctttatc atgagcaatg gcgatgtgct tgcccttact gctgactcag ctcgtatcgc
     8821 aggtcatttc aacgcccaag atatctatgt cgatggaaat cgtatcggtg aaattggcgc
     8881 agctgtcctc aaagatcgtc gcgatctatc tgaagacggt gtcgttctgg cagtcgcaac
     8941 tgttgacttc aaatcgcaga tgattctatc tggtccagac atcctcagcc gaggctttgt
     9001 ctacatgaga gagtctggcg acttgattcg ccaaagccag cgtatcctct tcaatgccat
     9061 tcgtatcgca ctgaaaaata aggatgctag cgtgcaatct gtcaatggtg ccattgtcaa
     9121 cgctattcgc cccttcctct atgaaaatac cgaacgtgaa ccgatcatca tcccgatgat
     9181 cctcacacca gatgaagaat aaagcaagaa aacagccccg tcctcggagc tgtttttctc
     9241 tatgctttct tttgagatta aaactcaatg aaaatcagac cagaaggcta ggaaaatgca
     9301 taacttgagt tagctcccat agttcgggga actatgggag attggagatg aatcaaagcc
     9361 aagctttgaa ctcattcgta agaagcctac gacatatcat tttgattttt gaagagtttt
     9421 agaaatacta cgatttttac cttccagata caccatcaaa atagaaatat ctgctgggtt
     9481 tactcccgaa atacggctgg cttggccgat ggtttctgga ttgatgagtt tgaacttctg
     9541 acgggcttcg gttgcgatag aatcaatgtc atcccagtcg atattggctg gaatacgttt
     9601 ttcttccatg cgcttcatct tagcaacctg atccatggct tttgagatgt aaccttcgta
     9661 cttgatttct gtttcaatca attcgataat cttgtcatct aattcctctg cagctggtcc
     9721 gatgaaggcc accacatctt ggtaagaaac ttctggacgg cgaaggaatt ccttggctgt
     9781 caccgcatct gtcaacggct tgaagcccat ttcctcaacc ttagcattgg tttccttgac
     9841 tggcttgagt ttgatactgt ctaggcgctt catctcatta tcaaattgat ttttcttgat
     9901 ttcaaaacga gcccagcgtt catcgtccac aaggccaatc tcgcgtccca tctcagtcaa
     9961 gcgcatatca gcattgtcat ggcgaagaat gagacgatat tcagcacgac tggtcaagag
    10021 acggtaaggt tcaatggttc ccttggtcac caagtcgtcg atcatcaccc cgatataacc
    10081 gtcacttcgt tttagaatca attcaggctt gccttggatt ttcaaagccg cattgatacc
    10141 cgcgataatc ccttggccag cagcttcttc ataacctgat gttccatttg tctgaccagc
    10201 agtgaagaga cctgagattt tcttggtttc caaagtcgca cgcaactgat gaggcaagac
    10261 catgtcgtac tcaatggcat aacctgttcg catcatctct gtattttcca aacctttaat
    10321 ggaatgaacc aagtcacgct ggacatcctc aggtagactg gttgagaggc cttgcacata
    10381 gacttcctct gtattacgtc cttctggctc aaggaagagt tggtggcgtt ccttgtccgc
    10441 aaagcgcaca atcttgtctt caatcgacgg acagtaacga ggccccactc ccttgaccac
    10501 acctgtaaac ataggcgcac ggtggaggtt gttttggata atctcatgac tggtaccatt
    10561 ggtgtaggtc aaccagcatg gcacttggtc cttgacataa tcctcatcac gtgaagtgta
    10621 tgagaagtga ttaggcgctt catctcctgg ttggatttct gtcacatcgt aattgataga
    10681 agaagccttg acacgtggag gggttcctgt cttgaaacga ccgatttcga ggcccagttc
    10741 cttgagattg tcagctaggt taatagaagc caagctgtgg ttaggacctg atgagtactt
    10801 gaggtctccg atgataattt ccccacggag agcagtccct gtcgtcacaa taacagcctt
    10861 agcagcatat tcttgatggg tggctgtacg cacaccgaca accttgccat cttccaccaa
    10921 aatctcatta atcatggttt gacgaagggt cagattttct tgattttcaa ctgtcttgcg
    10981 catctcctta gagtaaagtt ccttgtcagc ctgcgcacga agagcacgga cagctggccc
    11041 cttccctgtg ttgagcatct tcatctggat gtaagtcttg tcaatggtct tggccatctc
    11101 gccaccgagg gcatcgactt cacgtacgac aatcccctta gcagaaccac cgatagaggg
    11161 attacaaggc atgaaagcca gcatttcaat gttaatagtc gcaagcagga ccttacagcc
    11221 catacggcta gcagctaagg aagcctcaac cccagcgtgt cccgcaccaa ttacaataat
    11281 atcgtattct tcagtaaaat gataagtcat gtttctctcc tattcttcaa gatgaatgtg
    11341 tcttagttgg ccttcccaat ctggtagggc cgtttttaaa aaggctggaa ctagctggat
    11401 atcctcaagc ttatccaagt caatccactc acagggctgc cttttctcat cttcctgcat
    11461 ggtcaacggg gcatcttcaa gcaaatccac cagataatga aactcgatat tgtgatagga
    11521 aacgccgtct tgttcaaaac gattttcaac cacaaaagct agctgcccag cttgagcttt
    11581 gacacccagt tcttccttca cttcacggac taccgcgtct tccgtgcttt cattgacttg
    11641 aatcgcacct ccaatagtgt aatacttgcc cttgtctttg gtaactagaa gcttgtgatt
    11701 ttggacaatc aaggctgtag cccgaacacc aaaaaccgta ttgtctactt ttgtccgaaa
    11761 gtcttgttga gtcattcttg tcctttccct taaacgacac aaaaacagtc aaaactacaa
    11821 agaagtgcag gacaaaaaag cctgcaacat ccatgagctt tgaccatcat ttctattgct
    11881 gttattattg tagcaaattg agaaaatttg tcaatctaaa tgtactgaca aacttgtcca
    11941 tcgcggtaag cattgtcaat caaaccgcca cctagacact cttcgccatc gtaaaagaca
    12001 actgcctgtc ctggtgtaat cgcgcgttgt ggttctgcaa agataacttc tgccttgtct
    12061 cctttgacat ggacggtcac cttagagtca ggctgacggt aacggaattt agccgtacat
    12121 tctagcgtaa actcttctgg catttcacga gtaaagtgga cttgactggc ttctaggcta
    12181 gttgacatga gcgagtcatg gtagaatcct tgtcctacat agagaatatt cttgcttaga
    12241 tcttttccga caacgaacca aggggcattg tcaccaccgt gttgcccacc gataccgagt
    12301 ccgccacgct gaccgattgt atagtacata agacctgcat gctcgcccat atcgcgacca
    12361 tccacagtca tcatacgacc aggctgagct ggcaggtagt tgctgagaaa gtttttaaag
    12421 ttcttttctc cgataaagca aatccctgtc gagtctttct tcttagcagt cgaaagacct
    12481 gcttcttctg ctagttttcg aacttcaggc ttttccaaat gtcctagtgg gaacatcgtt
    12541 ttttgaagtt gttcttgcga aagttggctg aggaaatagg tctgatcctt gccattgtcc
    12601 acgccacgaa gcatgtgaac ggtaccatcc tcatcacgca ccactcgagc ataatgccca
    12661 gtcgctacat agtctgcccc caaggtcata gcatagtcca aaaaggcctt gaacttgatt
    12721 tccttgttgc acataacgtc cggatttggc gtgcgtcccg cacggtattc cgctaggaaa
    12781 tactcaaaaa cgcggtccca gtactctttt tcaaaattga cagagtagta gggaatgcca
    12841 atctggtctg ccaccgcaac cacatccttg taatcttcgg tcgccgtaca gacgccgttt
    12901 tcatctgtgt catcccagtt cttcatgaag ataccgatca catcgtagcc ctgctccttg
    12961 agcaaaagag ccgtcaccga cgaatcaaca ccaccactca tccccacgac aacacgtgtt
    13021 ttagagttat cactcatggt aagtctccca tctattcgtt tattcacgat tgaaggtcgt
    13081 gtgtgcttca cgattgaagg tcgcttgagc agtattcatt ataacacgct tggttagaga
    13141 agacaaggaa gagcttaaaa attgtttttt aaaacttata gtcaatatac agatcatgtg
    13201 aatgacgtga gtataccttc ttcttatctt cattcaaata actataataa ataaaacaac
    13261 ccattttctc taatctattt ttcaagttag agaaaaggag tcgttttttt aatgacattt
    13321 cctgaaatca taagataggt acctaaagaa tacgaacata aatttattca atcgaacctt
    13381 atctttgttt caaaattaaa atgtcaaatg ttcttaacat gatttaattt aatcggctta
    13441 aacccattca ccattggcat tgactttata gccatctaca gttgtgttga ctgcaagggc
    13501 acctaaacca ttgacatagt accatttatc tgatactttg aaccattggc ttgctttcat
    13561 agcacctgat gcttcaagat agtaccaggt atctccatct tttacccaac ctgttgccat
    13621 tgaaccgtta gcgttgaggt agtaccatga accgttgact ttaacccaac ctgttgccat
    13681 agcaccgtta gcgttgaggt agtaccatga accgttgtat tggagccaac ctgtagccat
    13741 agcaccatta gcgttgaggt agtaccatga accgttgact ttagcccaac ctgttgccat
    13801 agcgccgcta gcgtttaggt aataccatga atcgttgttt tggagccatc ctgtcgccat
    13861 agcaccatta gcgttgaggt aataccatga accgttgttt tggagccatc ctgtcgccat
    13921 tgaaccatta gcgttgaggt agtaccatga accattgttt tggagccatc ctgtcaccat
    13981 tgaaccatta gcgttgaggt agtaccatga accattgttt tggagccatc ctgttgccat
    14041 tgaaccatcc gtattgtaga agtacc
//
LOCUS       DAVMCG010000045        13389 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVMCG010000045 DAVMCG010000000
VERSION     DAVMCG010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.046"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            101..1279
                     /locus_tag="VYP66_001739"
     CDS             101..1279
                     /locus_tag="VYP66_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1851245.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1507..1953)
                     /locus_tag="VYP66_001740"
     CDS             complement(1507..1953)
                     /locus_tag="VYP66_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851246.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDNISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            2023..2682
                     /locus_tag="VYP66_001741"
     CDS             2023..2682
                     /locus_tag="VYP66_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1851247.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(2734..3885)
                     /locus_tag="VYP66_001742"
     CDS             complement(2734..3885)
                     /locus_tag="VYP66_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1851248.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3900..4631)
                     /locus_tag="VYP66_001743"
     CDS             complement(3900..4631)
                     /locus_tag="VYP66_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851249.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            4860..4961
                     /locus_tag="VYP66_001744"
                     /pseudo
     CDS             4860..4961
                     /locus_tag="VYP66_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(4933..5709)
                     /locus_tag="VYP66_001745"
     CDS             complement(4933..5709)
                     /locus_tag="VYP66_001745"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1851250.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIKTEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDITLIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(5702..6925)
                     /gene="trpB"
                     /locus_tag="VYP66_001746"
     CDS             complement(5702..6925)
                     /gene="trpB"
                     /locus_tag="VYP66_001746"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1851251.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(6903..7502)
                     /locus_tag="VYP66_001747"
     CDS             complement(6903..7502)
                     /locus_tag="VYP66_001747"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1851252.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKDGISGTK"
     gene            complement(7489..8256)
                     /gene="trpC"
                     /locus_tag="VYP66_001748"
     CDS             complement(7489..8256)
                     /gene="trpC"
                     /locus_tag="VYP66_001748"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1851253.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(8253..9257)
                     /gene="trpD"
                     /locus_tag="VYP66_001749"
     CDS             complement(8253..9257)
                     /gene="trpD"
                     /locus_tag="VYP66_001749"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1851254.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNLGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLEMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9268..9834)
                     /locus_tag="VYP66_001750"
     CDS             complement(9268..9834)
                     /locus_tag="VYP66_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1851255.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(9831..11192)
                     /gene="trpE"
                     /locus_tag="VYP66_001751"
     CDS             complement(9831..11192)
                     /gene="trpE"
                     /locus_tag="VYP66_001751"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1851256.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKIILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDAFYSERSQEALEKSLNQV
                     LEELRIPVPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSDYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKTLATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMKVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(11327..11482)
                     /locus_tag="VYP66_001752"
     CDS             complement(11327..11482)
                     /locus_tag="VYP66_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851257.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            complement(11694..11771)
                     /locus_tag="VYP66_001753"
                     /pseudo
     CDS             complement(11694..11771)
                     /locus_tag="VYP66_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12376..13377)
                     /locus_tag="VYP66_001754"
     CDS             complement(12376..13377)
                     /locus_tag="VYP66_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1851258.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         3871 a         3005 c         2300 g         4213 t
ORIGIN      
        1 ccagtaagta atgaaaagct taaaaagatt aacatctaca tttatccata gcaaaaaatc
       61 ataggatttt aagaatctga caactaggaa gaaaactaat atgaccttat ctaagaaaca
      121 attacaacta agagctaaaa tactggaaac agtttacaca ttaggtccca tttcacgaat
      181 tgaaatcgct actaaaacag gaataacacc tgcaacaact agcagtatca caaatgatct
      241 gattaaagaa aatattctct tagaacttgg tgaagacgaa cacgatacaa gcgtagggag
      301 aaaaaaaatc ctgctagaca ttcaagctaa acgattttac tacattggtt gtgaactatc
      361 tgaaaaacat ttcacttttg ctttaggaga taatctagga aatatcttaa aggaagagaa
      421 agaaattgtt actaaacagt taatccaaga aaagggaaat caactcatta accagacact
      481 aaagcaattc ttaaataact gctctgatta tgaaatagaa gcaattggaa tcgcgctacc
      541 tggtcgctat ttagatgatt ataaaataac aacaaacaat cctttatggc aacatatcga
      601 cttagaaatg attcaatccc actttgataa gcctttgttt ttctctaaca atgttaactg
      661 tatggctata ggtaaacgcc tatttagtcg ccaacagaat gaccctaatt ttgcttattt
      721 tcattttgct agaggtatgc actgttctta tatctacgac ggaaacattt atggaaaagg
      781 aaatctaatg attggagaaa tagggcatac agttgtttca tctgagggag aagaatgtag
      841 ctgcgggcgc aagggatgct tacaaacttt tgctggagaa tcttggttaa tcaaaaaatc
      901 aaaaattcta tatcatcaat ctccctattc tctacttcct agtttagtca aaaatgccga
      961 tgatattgat atccaagtta ttttaaccgc ttatcaatta ggtgacactg gaataatcac
     1021 acttatccat caagccttac tctatcttag tcaaaccatt ttaaatatca gtatgatgat
     1081 tgactctcaa aaaatctacc tacatagtcc tttactaaca aatcaacaca tcatccaaaa
     1141 actatatagt gaaatgaact acaaacccaa actgctctat aatcgcctac ctgaagtcat
     1201 tattgaacct tacaatgatt ttacagccgc acactcagct attgcacttt gtttgtatca
     1261 tacaattcta cattcttaat tttctattac atttaataaa taggctaaaa agagggagta
     1321 tatcataaaa agcgaataaa cctgttttct gaaaatcaga attctgtttt gttcgctttc
     1381 tttatatttg gaattatact cctatctccc atttttcata atgtatagta aaatgaaata
     1441 ataacaggac gaatcgatcg ggacagtcaa atcgatttct aacaatgttt tagaagtaga
     1501 ggtgtactat tctagtttca atccactata ttttcgtaca ggtgcttcaa ccatttgaac
     1561 gatttcaaat ccttcttttt ggtaaagatt ctgagctctt tgatttgcct cgaagacatt
     1621 tagagaaata ttatctatat cttcattttc aaaggccaaa ctaacaaatt tccttaaagc
     1681 ctggctacct aagccttgcc cctgtttctg ggggttgata aaaaatctcc cgatatgaag
     1741 attgctgtct tctagcctga ttttctggat aaggcccaca aactcttgtt catcaaagat
     1801 tgaaaatact tcttccaagg cttgaagggt cagtagaaaa ggaatccttg gtcccatcca
     1861 ttgttcttga aaggatttgc ctagggagtt ggaccattgg catacaaatt gagcgttttc
     1921 tatactcacc ttttcttcaa aacgaattgt catcttttcc tcaccatctt atctatgttt
     1981 ctccattata ctatttctcc cattttttac gaatagataa gtatgattga tttttatttt
     2041 tttctcgtcg ggagcattct cgcttccttt cttggtttgg tcattgaccg ttttccagag
     2101 caatccatta tcagttcagc cagtcactgc gattcctgtc agactcgctt gcgtccctta
     2161 gatttgattc cgattctctc acaggtcttc aatcgctttc gctgtcgcta ctgcaaagtt
     2221 cgctatcctg tctggtatgc cctctttgaa ctaggcttag gactcctctt tctgctttac
     2281 tcttgggaat tgctttcctt ggggcaagtc gtcctaatca ccgctggttt gaccttgggt
     2341 atatacgact ttcaccatca ggaatatccc ttactggtct ggatgacttt ccacctaatc
     2401 ctaatagctt cctctggctg gaatctggtc atggtctcct tcctcatact tggaattttg
     2461 gctcatttta ttgatatccg catgggtgca ggggatttcc tctttttagc ttcttgtgct
     2521 ctcgtcttta gcgtaacgga gttactgatc ttgattcagt tcgcttctgc gacgggtatc
     2581 ctggcctttc tcctgcaaaa gaaaaaggaa agacttcctt tcgtgccttt cctcttactt
     2641 gctacttgtt tgattatttt tggtaagcta ctacttgttt gataaattcc aatttctgcc
     2701 atatgtactc catgaaatta tttcacagtt aaattataaa ttatttcttt tgtacaaagg
     2761 gatgatgtta tcaaatcgat ctgttcttct atcttcttga tactgatcaa aaaatttcat
     2821 ttcgactgaa aatatttcgc ttataaactg taaacgaata ctttgtttag acattatagt
     2881 cgctagactg actagatgat tactcaaaac gacgtccaga atactcttta ctttgcttgg
     2941 ttttttaaca aaaatttgat catccaaagg ttcaatcatt ttgtaacctt tttgcgcaat
     3001 ttgacgataa aagtaagaat gttgctttgg agtcaataat cctaacttaa aagctcgata
     3061 ctctaaagcc tgtatcgaaa cattcaaatc cgacttcaat aaaatataac tatcaggatt
     3121 gctgacacgc ttgccaaccc tctcttcaaa tttgactaaa aactcttctt ttggcaataa
     3181 aaaacatgat gcaaaataat ttgcttcttg ctccaaacga tcgccatctt cattcatatc
     3241 tttatattta tgtaaaagaa tatgtcctag ctcatgagct aaatcaaaat ttcgacgtac
     3301 agatgattta ttcgttccca acacaatata aggtcttccc aattttgacc atgcgctata
     3361 agcatcagct tggccattaa ttaatcgttc cacgatatag atgcctgaac gttctaattt
     3421 ataaagcaaa tcatgattat cttttgaaat acctaatttt tccctggcat aaagagccaa
     3481 ttcctcaatg gattctccct tatgataaga ttcactcact acattactta ggtcatgaat
     3541 tgtaatatta ggtataatta caaaactttc aaaataatca atcaaactat ctaccttatg
     3601 taaatacata gtttgaatat ctattgtttt ccgggttgct aggtctgcat ttctaaaggc
     3661 aattacagaa gaatcaaatc gaatgctctc ttcttcctgt tcaaaataag ttaaatcaac
     3721 atgaaattgg ttggccaaat gcattttggt tgataattta ggtttcgttt cgttggactc
     3781 aaactgccaa atggcttgtt ccgttaaatt aattctctga gctaattctg ctctacttaa
     3841 accatttaac agccgtaatt ctttcaatac ccgaccatta aacatttaca tactccttac
     3901 tacttttgac cttcttgttt ttctattctt ggaataattt caaaatcttc tgtttccgat
     3961 aattctgaaa aattaggaat atcttgatat ttagcttctt cgaaatggta cgaacttgat
     4021 tgaatatact cagacaaatc ttgaatcaag tgtaactgac cagttcgtgc atcaggcata
     4081 acaacatcta cagatataat attgttttct gagtccgcct cataagttaa aatcataaat
     4141 ttttcgatat tcgaattttt agtagcttgt tcaatttctt gaatcatttc atcagaaact
     4201 aactccatct gaattggaaa ggaatgacta tcttcatcat ttttgtagga agaatgttga
     4261 ttaagataaa gtgtattcat ctgagcatat tcaaataagt agccactctt atttttttgt
     4321 accaaaggaa attggttcgt aagtcgcttc ttacccttta taattaacaa tactttccca
     4381 tatttttctg tgtttgtttc aaattctaaa tatccccaag tctgtcctgc taattgtaat
     4441 ttatactcaa acaaatctgc tgatgcaaat gcagtatcaa tatgattagg tcgcgtccat
     4501 gcataaccat tcgacactat cattgtctct cttttttcta gacgttcatc tacataatct
     4561 ttttgccctt tcatcaaagt atctacaatt ttttgtgcct caagcgaatc aaagagatcc
     4621 tgattcaaca taattcttcc tcctccaaat actttttaat gaattatatc attttcttaa
     4681 agaaattact acaataatta gctttttctt aaagttctgt gtcagagtaa tttagaaaat
     4741 tatatcttct atagtaaaat caattaaaaa ctgaacaaat ttattgggaa attcaaatca
     4801 ctttctaaaa atattttagg aaccgtagtg taatattcca gattcaattt actataaaac
     4861 tagcctttct cctgcaaaag aaaaaggaaa gacttccttt cgttcctttc ctcttacttg
     4921 ctacttgttt gattattttt ggtaagctac tgcttgtttg ataaagtcct gaatcggctc
     4981 tccttggtgg agagctttta ctattttcga accgacgata acaccatctg acaccgcatt
     5041 gaagcgttcc agatcggctt gactagatac accaaaacct gtcaagactg ggatgtcggc
     5101 cacttgatga agttgcgcca agtgcttgtc caaatctgca cggtaattgc ctgatttccc
     5161 tgtcactcca ttgatggcaa cggcatagac gaatccctcc gccccttcaa tcaactcttt
     5221 ctggcgctca attcctgtgg tcaagcttac taaaggaatc aaggtgatat ctgtatctgc
     5281 caaaaatggt tctacaaagt tggcatgttc atgaggcaag tctgggataa tcaagccctt
     5341 cacagctgta tcagccagat ctttgacaaa gttctccaca ccgtactgaa agagggggtt
     5401 gaagtaggtc atgatgacca gtggaatctc tgttttaatg gttttcaagg tttcaactaa
     5461 agcctgggta gaggtcccgt gggctaaact gcgcaagcca gcttcttcga taacaggtcc
     5521 atctgcaaca gggtctgaaa agggaatacc cacttcaatt gcagagacac ccaaatcttc
     5581 taaaaagtgg attgtttctc ctagtccatc caaacctttc tcgtggtctc cagccatgat
     5641 atagggaaca aaaattcctt ttccagctgc ttttatagca tttaattttt ctgttagtgt
     5701 cttaggcatg agcttctccc ttctttgctg catctgcttc caagcggtct ttgacttgaa
     5761 ccacatcctt gtccccacga cctgataggc atacaatcat agacttttct ggtccaagtt
     5821 ctttggccaa tttcaccgca aaagcgatag catggctaga ttccaaggct gggataatcc
     5881 cttccacacg agacaagagt tgaaatcctt ccaaagcttc ttcgtctgtc acagggacat
     5941 agctggcacg tttgatatcg tggtagtgag aatgctctgg accgatacca ggatagtcca
     6001 aacctgctga gatagagaag gcttcaagaa tttgaccatg ggcatcttgg agcacatcca
     6061 tgagagaacc gtgaagaaca cccggacgac ccttggtcaa ggtagcagcg tggtgctctg
     6121 tatccacacc aagcccagcc gcttcagctc catacatggc tactgactca tcttctacaa
     6181 agggatggaa gagcccaata gcattagatc caccaccaac acaggctact agggcatctg
     6241 gcagatctcg acctgtcaag tcacggtact gttgtttagc ctctcgaccg atgacacttt
     6301 ggaagtcacg aacgatttct ggaaatggat gaggccccaa ggcagaacca aggatatagt
     6361 gggtatcgtc gatattagcc acccatgaac gaagggctgc attgaccgca tccttgagca
     6421 cgcgcgaacc atctgtcacg gcctcgacct tagctcccaa aagctccata cggaagacat
     6481 tgagggcttg gcgtttgaca tcttcctcac ccatgtagat ggtacattcc atgttaaaga
     6541 gggccgcagc agttgcagtt gccacaccgt gctgaccagc acccgtttct gcgataattt
     6601 tctttttacc catgcgtttg gcaagccaaa cttgtcctaa ggcattgtta atcttgtggg
     6661 ctcctgtatg gttaaggtct tcccgtttga gataaatctt ggctccgccg atatgctggg
     6721 tcaaattttt tgcgtagtaa aggggagttt cacgtcccac atactggcgc aaaagttggt
     6781 ttaattcctc ttggaaactt gggtctgcct gactttcacg gtaggccttc tccaactcca
     6841 aaactgctgt catcaatgtt tctgggacaa aacgtccgcc gaattttccg taaaatccat
     6901 ctttatttgg ttcctgatat gccatccttt accctctcta taaatcttct aatcttttca
     6961 tgatcttttt gtccatctgt ctccactcca ctcgatacat ctactgcata gggagtaaaa
     7021 tgttgaattg cttttactac attatcttca ttaaggccac ctgcgataaa gaagggctgt
     7081 gctagtccag tcgtatccag ttgaccccaa tcaaaggact ggccacttcc tgccacaggg
     7141 gcatcaaaga gtagataatc tgcctgagaa ttggggacat gcccatttcc atctacctgc
     7201 acagcctgaa tactggcaca aggcaaattc tcaaataaat catctgccac ctgaccgtga
     7261 acttgaacca agtccaagcc aactttgtca atcgcttcca gcagttctac ccgacttggt
     7321 gaaacaaata ctccaacctt tttcacatct gcaggaataa gctttgccaa ctcagctgcc
     7381 tcttctaaag tcacctgtct tttactaggt gcaaagacaa aaccgatata gtcggctcct
     7441 gctgaaacgg ctgtttccac cgcttctttg gtcgatagtc cacaaatttt aacctttgtc
     7501 aatctgcaac tccttgattc tctgggccac attttctgcc tgcataagag ctgtccctac
     7561 caaaattccg ttaaagtatg gggctagtcg ttccgcatcc tgccctgtga aaatggcaga
     7621 ttcagaaatg taatagcgac cttcctcaaa gtaaggggct aaatctacac tggtctgcaa
     7681 gtcgacctca aaggtagtca agttgcggtt gttgaccccg ataatctcag caccaagtct
     7741 gtgggctacc tctagttcag ctagattgtg agtctccact aagacttcca gaccaagctc
     7801 tgtcgcgtag tcatacagtt ccttgaggcg ttcttcggac aaggctgcca caataagcaa
     7861 gataactgtc gcacctgcat tgcgagcgcg gatgatttgc ttttcatcta tgataaagtc
     7921 tttgttgagc gtcggaatct ctacctgact ggaaatttcc cgtagataat ccaaatgccc
     7981 tttaaagaaa acctcatctg tcaacaccga aatcatcact gctccgtttt cttcataagt
     8041 ctgggcctgt tgcacaatat ccacatcgag attgatatct cccaaactag ggctagcttt
     8101 cttgacctca gcgattacct gcaagcggtc ctgatgattc ttcaaaaatt ctgccaagcg
     8161 ataggtctgg cgcagaggct ggatttgctc cagcttcatc tgctccacct cacgcgcctt
     8221 ctgctctaag attcgtgcta aaaattcctg actcattttt ggtactcctg taacagtctg
     8281 agtttttcaa gggccttgcc tctagcaatc acttgacggg ccaaggcaac tccttccttg
     8341 atgctatcaa tcttaccatt agcatagaaa ccaagaccag cattcaagac tgtcgtttcc
     8401 aagaatggac ttgcttcgtt tttcagaacg ctaagcaaaa tttctgcatt ttcctgagca
     8461 ttcccaccac gaatatcttc catagcatag ccttccattt ccaaatcctc tggagtaaag
     8521 cttgacaagc tgatttcgcc attttcaaga agtgcaatct tggttgttcc gttcaagcca
     8581 gcttcatcca acccttctgg tccagcaacc acgatggcac gtttgcgacc cagatttttc
     8641 aaaacctgag ctgtactttc taggagttct ggacgactaa ttccaagaag ctgtgtttct
     8701 aaagccattg gatgaatcag tggaccagtc aagttcataa tcgttggaat tcccaattcc
     8761 aaacgagctg gcatgatgta tttcatagct gggtgcatat ttttagcgaa gagaaagacg
     8821 attccagttt tatcaaagac cttacctagt tcagctggtt tgagatcaag attgattccc
     8881 aaggcttcga ggacatctgc ggaaccagat ttagaagaaa tcgagcggtt accatgcttg
     8941 gccatgtgaa taccgccacc agccaagaca aaggctgcag ttgtggaaat attaaaactg
     9001 aaagacttgt ccccacctgt accacagtta tccatggcat catgaatctc agttggaata
     9061 tgctgggcat gtcctctcat gacttgggca atggctgtgc gttcttcagg tgtttccccc
     9121 ttcatcttaa gagctaagag gagagaagca atctgcgctt cagttacacg cccagttacg
     9181 atacgctcaa tgacatccgt catttccaca cctgataaat tttcaaattt tgctagtttt
     9241 tcaataatct ctttcatcct agtttcctca ctttacaacc tcctcgataa aattccgaat
     9301 agaagacaag ccgtctggcg ttccaatgct ctctggatgg tactggaagc cataaatcgg
     9361 taggttttta tgttgaatcc ccatgatggc ttggtcatca gtcgaacgag ctgtcacttc
     9421 aaagtcttct ggcatttcct caatcaaaat actgtgataa cgcatgaccg cacggccatc
     9481 ctcaatacct tgatacaaaa cagatggcgc ttcaaagttg atattgctct gtttcccatg
     9541 catgactttt ggagccaaac ctagcttacc accaaagact tctgcaatgg cttggtggcc
     9601 caaacaaatc cctagaatcg gcttcttgcc tgcaaaatca cgaatcatgt cttccatctt
     9661 tccagcatca actggccaac caggaccagg agaaaagacc agaccatctg ctttttcagc
     9721 ttcttcatac agcttggaat catcatttct caaaacctga acttctgcaa aattcccaat
     9781 gtattgggcc aagttatagg taaaagaatc atagttgtca atcaataaaa tcatggtctt
     9841 agttctccaa ttctagtcat agattttgct ttgttaatgg tttcttggta ttcgttttgg
     9901 gcgatagagt cgtagacaat ccctgcccca gcctgcacat aggctctttg atttttgaga
     9961 atcatggttc ggatggcaat ggccaaatcc atatcacccg tcgcagacaa gtagccgatt
    10021 gctcctgcat atacgccccg tttttccgtt tccagttcat agatgcgtct catcgctcga
    10081 atttttggtg ctccagaaac ggttccagca ggaagcgttg ctttcaaggc atccatagca
    10141 gtgagttctg caagcaaacg ccccttgacc acactggtca aatgcatgac gtagcggaag
    10201 agctccacct tcatatactt agtaacttgg acactggccg tttcagagat gcggccaata
    10261 tcgttacgcc ccaagtctac caacattcga tgttctgctg tttccttctc atcagagagg
    10321 aggtcagtcg ccaaggtctt gtcttcttca tccgtagccc ctcttggtcg cgtccctgca
    10381 atcggattgg ttgtcacgat gccatttttg acagaaacca aactttctgg actagctccg
    10441 atgatttgat aatccccaaa atcatagaaa taaaggtaat cagaaggatt agtcacgcgg
    10501 agatttctgt agaagtcaaa tggatttcca gtaacttctg ctgagaaacg ctggctgagt
    10561 acacattgga acatatctcc gttacgaatc aagtcacgag ctgtttctac cattccctca
    10621 aacttatgtg gagcgatatg cggtttgaag tctaacggag atagatccaa gtcttcaaat
    10681 tcatttggaa caggaatgcg taattcctca agcacttggt tcaaggattt ttccaaggcc
    10741 tcttgactgc gctcactata aaatgcatcc tctatgacat gtatcttctc cttcttgtgg
    10801 tcaaagacta tatagctctc atagacaaag aaatgcatgt ctggcgtccc aattgtatcc
    10861 tcagggattt gaccaatttc ttcataaagc gaaatcatat cgtaacccac aaaaccaatg
    10921 gctccaccac caaaaggtag ctctgaatgg tgctgactct tatgaatcac ttcataaagg
    10981 aaatccaagg gatcccgatc aatcacttga ccattttgat aaagaactcc attttcaaac
    11041 ttaatctcaa aaacaggatt ataggctagg atagaaaaac gagctgtttc cttgtctctc
    11101 ggaatactct ctaagataat cttgtgttgc ccctttaagc gcatataagc caagattggt
    11161 gataagacat ctccatgaat gattcgttcc attgtaattt ccctttcagt tctaattcta
    11221 gttcgtagcg actgtatgaa aaatccccac gcaaaataac ttgcgtgagg acgaaattcg
    11281 cggtgccacc tcaattatag gatttctcct atctctcatt cctgtctcag atatctcctg
    11341 taacaggctg tgcgataaag ggcactccct tgagaatgat gttttcttct ctcgtttcag
    11401 atgaacccaa ctttacagct ttctctgctt gtttccagca accacaagct ctctgtgaga
    11461 gaaagaactg taatttttcc atctattatt ttttagcttc taggtagtct gcaatcgcag
    11521 ctaggtcctt gcctccacga ccagagacat tgatgaagag atgttcatct cggtacacct
    11581 ttatactctt cgaaaatctc ttcaaaccgc gtcaacgtcg cctttccgta ggtatggtta
    11641 ctgacttcgt cagttctatc tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtt
    11701 ctatccacaa cctcaaaaca gtgttttgag cagcctgcgg ctagtttcct agtttgctct
    11761 ttgattttca ttgagtatta ctagcttttt tcgtattagt ccagcctttt tgtttgcttt
    11821 tagtagtagg caaggagctg tagatagaac tcaagttcat caaagcgact taaggcccta
    11881 ataaaagata aaccaaacga cggatagaaa aaagcccaca cacagaatat acttccgtgt
    11941 gagggcgttg gtaacgcggt gccacctcaa ttataaaggg actatccctt tacatctctg
    12001 ccttgtttaa caacaagctg cactgtaagg tgtgcgcacc gaattttcat tgtttcaaat
    12061 tcattttcaa aatcagccca ctttcactac ttccaaccac ctattcacaa tcaccacagg
    12121 ctccctgaag atcaaaaata gttacttttc tgatttgttg aacttatttt aatactttgt
    12181 tttttctttg tcaagacttt tttacgattt ttttgatatc attcgaatgt gaccatatct
    12241 tccttagatc gaacatgaac atgtcccact tgttagaaat tggatccaac tcaatagaaa
    12301 ctgaatggag gctaaacaga acttatttta gaacactcca tcttttccac taggattttc
    12361 aagaattaaa caatactaga aactctgtct cctaacaaat ttaggagaaa cttcaacaga
    12421 tgtgacactt tcccctttaa taattgctaa aacaccttct atcatttctt tagccaattt
    12481 aacataattg ggagcaattg tagacaaagc tggagtataa tactgagaaa taggaatatt
    12541 atcaaatcca ataatagaaa tatcatctgg aataagaatt cctttctcat agcacgcacg
    12601 aatcaagccc tgaacctttt catctcctga aacaaaaata atgtccggat aattttgggt
    12661 agtcaagtgc tgcattgcat aagaataaac tgaatcaatt gtagataagc cataaatgac
    12721 ttttaaatcc ataaagtaat ttttatcatt cagaaaagaa cgcacacctc tttcacgatc
    12781 cttattaaca tgagattctc ctcccataag caaccacata tttttaaatt tttcttcagt
    12841 tacagctttc atcatatcat aagtagcttg aaaattatta ttagatacat agactactcc
    12901 agacgtttga gattcaccga aaacaagaaa aggcatatgg ttcttcttta aatactgaat
    12961 tctgatatca tctacacttt cataaaaaac aataacacca tctactaggc tacctgtgct
    13021 tgatataatt gaattactaa ttgtatcctc ctctccaaag tactcaacta tagcattaac
    13081 accaaattct ttacacgtcc gtaacacttt atctaacagc gtatgaaacc aaattaaagg
    13141 aaaagagtcg atttttttta cagaaatcaa tatatttata gcttcttttt tagttaaatt
    13201 ttttgcatac gcatttggaa tatacgacaa ttcctctata actttttgaa tcgcttgata
    13261 agtttcttct ttaacattta ctccaccatt aataactcgt gaaactgttt ttggagaaaa
    13321 acctgataaa cgtgcaatat cataaatagt tacctttttc ccatttatat ttttcatttc
    13381 agtcctcta
//
LOCUS       DAVMCG010000046        13279 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVMCG010000046 DAVMCG010000000
VERSION     DAVMCG010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13279
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.047"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            103..5673
                     /gene="zmpC"
                     /locus_tag="VYP66_001755"
     CDS             103..5673
                     /gene="zmpC"
                     /locus_tag="VYP66_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease ZmpC"
                     /protein_id="HEV1851259.1"
                     /translation="MSRKSIGEKRHSFSMRKLSVGLVSVTVSSFFLMSQGIQSVSADN
                     MESPIHYKYMTEGKLTDEEKSLLVEALPQLAEESDDTYYLVYRSQQFLPNTGFNPTVG
                     TFLFTAGLSLLVLLVSKRENGKKRLVHFLLLTSMGVQLLPASAFGLTSQILSAYNSQL
                     SIGVGEHLPEPLKIEGYQYIGYIKTKKQDNTELSRTVDGKYSAQRDSQPNSTKTSDVV
                     HSADLEWNQGQGKVSLQGEASGDDGLSEKSSIAADNLSSNDSFASQVEQNPDHKGESV
                     VRPTVPEQGNPVSATTVQSAEEEVLATTNDRPEYKLPLETKGTQEPGHEGEAAVREDL
                     PVYTKPLETKGTQGPGHEGEAAVREEEPAYTEPLATKGTQEPGHEGKATVREETLEYT
                     EPVATKGTQEPEHEGEAAVEEELPALEVTTRNRTEIQNIPYTTEEIQDPTLLKNRRKI
                     ERQGQAGTRTIQYEDYIVNGNVVETKEVSRTEVAPVNEVVKVGTLVKVKPTVEITNLT
                     KVENKKSITVSYNLIDTTSAYVSAKTQVFHGDKLVKEVDIENPAKEQVISGLDYYTPY
                     TVKTHLTYNLGENNEENTETSTQDFQLEYKKIEIKDIDSVELYGKENDRYRRYLSLSE
                     APTDTAKYFVKVKSDRFKEMYLPVKSITENTDGTYKVTVAVDQLVEEGTDGYKDDYTF
                     TVAKSKAEQPGVYTSFKQLVTAMQSNLSGVYTLASDMTADEVSLGDKQTSYLTGAFTG
                     SLIGSDGTKSYAIYDLKKPLFDTLNGATVRDLDIKTVSADSKENVAALAKAANSANIN
                     NVAVEGKISGAKSVAGLVASATNTVIENSSFTGKLIANHQDSNKNDTGGIVGNITGNS
                     SRVNKVRVDALISTNARNNNQTAGGIVGRLENGALISNSVATGEIRNGQGYSRVGGIV
                     GSTWQNGRVNNVVSNVDVGDGYVITGDQYAAADVKNASTSVDNRKADRFATKLSKDQI
                     DAKVADYGITVTLDDTGQDLKRNLREVDYTRLNKAEAERKVAYSNIEKLMPFYNKDLV
                     VHYGNKVATTDKLYTTELLDVVPMKDDEVVTDINNKKNSINKVMLHFKDNTVEYLDVT
                     FKENFINSQVIEYNVTGKEYIFTPEAFVSDYTAITNNVLSDLQNVTLNSEATKKVLGA
                     ANDAALDNLYLDRQFEEVKANIAEHLRKVLAMDKSINTTGDGVVEYVSEKIKNNKEAF
                     MLGLTYMNRWYDINYGKMNTKDLSTYKFDFNGNNETSTLDTIVALGNSGLDNLRASNT
                     VGLYANKLASVKGEDSVFDFVEAYRKLFLPNKTNNEWFKENTKAYIVEMKSDIAEVRE
                     KQESPTADRKYSLGVYDRISAPSWGHKSMLLPLLTLPEESVYISSNMSTLAFGSYERY
                     RDSVDGVILSGDALRTYVRNRVDIAAKRHRDHYDIWYNLLDSASKEKLFRSVIVYDGF
                     NVKDETGRTYWARLTDKNIGSIKEFFGPVGKWYEYNSSAGAYANGSLTHFVLDRLLDA
                     YGTSVYTHEMVHNSDSAIYFEGNGRREGLGAELYALGLLQSVDSVNSHILALNTLYKA
                     EKDDLNRLHTYNPVERFDSDEALQSYMHGSYDVMYTLDAMEAKAILAQNNDVKKKWFR
                     KIENYYVRDTRHNKDTHAGNKVRPLTDEEVANLTSLNSLIDNDIINRRSYDDNREYKR
                     NGYYTISMFSPVYAALSNSKGAPGDIMFRKIAYELLAEKGYHKGFLPYVSNQYGAEAF
                     ASGSKTFSSWHGRDVALVTDDLVFKKVFNGEYSSWADFKKAMFKQRIDKQDNLKPITI
                     QYELGNPNSTKEVTITTAAQMQQLINEAAAKDITNIDRATSHTPASWVHLLKQKIYNA
                     YLRTTDDFRNSIYK"
     gene            6029..6883
                     /locus_tag="VYP66_001756"
     CDS             6029..6883
                     /locus_tag="VYP66_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1851260.1"
                     /translation="MTYEYQSHIYLAEAVLNVKDLVSQTVFYQQIIGLEILSQTDTEV
                     VLGLGGKALVHLIQAQEGGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEALYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEVLAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSRQFYQTVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLDPRKQVLPGLAYYVIEVAHKEELLTIAQRAQEVDAPIKWMTSIQLEITDSDGI
                     VTRIRLAR"
     gene            6989..7546
                     /locus_tag="VYP66_001757"
     CDS             6989..7546
                     /locus_tag="VYP66_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HEV1851261.1"
                     /translation="MTSEYQKMIAGEFYRPSDPELRALAQASRQKQAAFNKEENPLKG
                     AEIIKTWFASTGKNLYINTRLMVDYGVNIHLGENFYSNWNLTMLDICPIRIGDNAMIG
                     PNCQFLTPLHPLDPQERNSGIEYGKPITIGDNFWTGGGVIVLPGVTLGNNVVAGAGAV
                     ITKSFGDNVVLAGNPARVIKEIPVK"
     gene            7763..8557
                     /locus_tag="VYP66_001758"
     CDS             7763..8557
                     /locus_tag="VYP66_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1851262.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHTFSCTGKGFVLS"
     gene            complement(8766..9008)
                     /locus_tag="VYP66_001759"
     CDS             complement(8766..9008)
                     /locus_tag="VYP66_001759"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851263.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSSKHCFEVADRTDEVSNIYTAR"
     gene            9226..10605
                     /locus_tag="VYP66_001760"
     CDS             9226..10605
                     /locus_tag="VYP66_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1851264.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            10619..11284
                     /locus_tag="VYP66_001761"
     CDS             10619..11284
                     /locus_tag="VYP66_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1851265.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            11594..11767
                     /locus_tag="VYP66_001762"
     CDS             11594..11767
                     /locus_tag="VYP66_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1851266.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGWDQVGNFSKGQYIMMHS
                     LIYRTDLLRASQF"
     gene            11834..12244
                     /locus_tag="VYP66_001763"
     CDS             11834..12244
                     /locus_tag="VYP66_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1851267.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEQLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            12360..>13279
                     /gene="pavB"
                     /locus_tag="VYP66_001764"
     CDS             12360..>13279
                     /gene="pavB"
                     /locus_tag="VYP66_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1851268.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADG
                     LNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     SPSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVK"
BASE COUNT         4256 a         2315 c         2940 g         3768 t
ORIGIN      
        1 gaaaagtact cagaaaattc catactatat tatttttatg tttatacttt tatgctataa
       61 aatatagatt gatataaaga atatagaaaa agcgaggtta atatgagccg aaaaagcatt
      121 ggtgagaaac gccatagttt ctcgatgaga aagttgtcag tgggattggt atcagttact
      181 gtatctagtt tctttttgat gagtcaaggg attcaatcgg tatcggccga taatatggaa
      241 agtccaattc attataagta tatgacagag ggtaaattga cagacgagga aaaatccttg
      301 ctggtagagg cccttccaca actggctgaa gaatcagatg atacttatta cttggtttat
      361 agatctcaac agtttttacc gaatacaggt tttaacccaa ctgttggtac tttccttttt
      421 actgcaggat tgagcttgtt agttttattg gtttctaaaa gggaaaatgg aaagaaacga
      481 cttgttcatt ttctgctgtt gactagcatg ggagttcaat tgttgccggc cagtgctttt
      541 gggttgacca gccagatttt atctgcctat aatagtcagc tttctatcgg agtcggggaa
      601 catttaccag agcctctgaa aatcgaaggt tatcaatata ttggttatat caaaactaag
      661 aaacaggata atacagagct ttcaaggaca gttgatggga aatactctgc tcaaagagat
      721 agtcaaccaa actctacaaa aacatcagat gtagttcatt cagctgattt agaatggaac
      781 caaggacagg ggaaggttag tttacaaggt gaagcatcag gggatgatgg actttcagaa
      841 aaatcttcta tagcagcaga caatctatct tctaatgatt cattcgcaag tcaagttgag
      901 cagaatccgg atcacaaagg agaatctgta gttcgaccaa cagtgccaga acaaggaaat
      961 cctgtgtctg ctacaacggt gcagagtgcg gaagaggaag tattggcgac gacaaatgat
     1021 cgaccagagt ataaacttcc attggaaacc aaaggcacgc aagaacccgg tcatgagggt
     1081 gaagccgcag tccgtgaaga cttaccagtc tacactaagc cactagaaac caaaggtaca
     1141 caaggacccg gacatgaagg tgaagctgca gttcgcgagg aagaaccagc ttacacagaa
     1201 ccgttagcaa cgaaaggcac gcaagagcca ggtcatgagg gcaaagctac agtccgcgaa
     1261 gagactctag agtacacgga accggtagcg acaaaaggca cacaagaacc cgaacatgag
     1321 ggcgaagcgg cagtagaaga agaacttccg gctttagagg tcactacacg aaatagaacg
     1381 gaaatccaga atattcctta tacaacagaa gaaattcagg atccaacact tctgaaaaat
     1441 cgtcgtaaga ttgaacgaca agggcaagca gggacacgta caattcaata tgaagactac
     1501 atcgtaaatg gtaatgtcgt agaaactaaa gaagtgtcac gaactgaagt agctccggtc
     1561 aacgaagtcg ttaaagtagg aacacttgtg aaagttaaac ctacagtaga aattacaaac
     1621 ttaacaaaag ttgagaacaa aaaatctata actgtaagtt ataacttaat agacactacc
     1681 tcagcatatg tttctgcaaa aacgcaagtt ttccatggag acaagctagt taaagaggtg
     1741 gatatagaaa atcctgccaa agagcaagta atatcaggtt tagattacta cacaccgtat
     1801 acagttaaaa cacacctaac ttataatttg ggtgaaaata atgaggaaaa tactgaaaca
     1861 tcaactcaag atttccaatt agagtataag aaaatagaga ttaaagatat tgattcagta
     1921 gaattatacg gtaaagaaaa tgatcgttat cgtagatatt taagtctaag tgaagcgccg
     1981 actgatacgg ctaaatactt tgtaaaagtg aaatcagatc gcttcaaaga aatgtaccta
     2041 cctgtaaaat ctattacaga aaatacggat ggaacgtata aagtgacggt agccgttgat
     2101 caacttgtcg aagaaggtac agacggttac aaagatgatt acacatttac tgtagctaaa
     2161 tctaaagcag agcaaccagg agtttacaca tcctttaaac agctggtaac agccatgcaa
     2221 agcaatctgt ctggtgtcta tacattggct tcagatatga ccgcagatga ggtgagctta
     2281 ggcgataagc agacaagtta tctcacaggt gcatttacag ggagcttgat cggttctgat
     2341 ggaacaaaat cgtatgccat ttatgatttg aaaaaaccat tatttgatac attaaatggt
     2401 gctacagtta gagatttgga tattaaaact gtttctgctg atagtaaaga aaatgtcgca
     2461 gcgctggcga aggcagcgaa tagcgcgaat attaataatg ttgcagtaga aggaaaaatc
     2521 tcaggtgcga aatctgttgc gggattagta gcgagcgcaa caaatacagt gatagaaaac
     2581 agctcgttta cagggaaact tatcgcaaat caccaggaca gtaataaaaa tgatactgga
     2641 ggaatagtag gtaatataac aggaaatagt tcgagagtta ataaagttag ggtagatgcc
     2701 ttaatctcta ctaatgcacg caataataac caaacagctg gagggatagt aggtagatta
     2761 gaaaatggtg cattgatatc taattcggtt gctactggag aaatacgaaa tggtcaagga
     2821 tattctagag tcggaggaat agtaggatct acgtggcaaa acggtcgagt aaataatgtt
     2881 gtgagtaacg tagatgttgg agatggttat gttatcaccg gtgatcaata cgcagcagca
     2941 gatgtgaaaa atgcaagtac atcagttgat aatagaaaag cagacagatt cgctacaaaa
     3001 ttatcaaaag accaaataga cgcgaaagtt gctgattatg gaatcacagt aactcttgat
     3061 gatactgggc aagatttaaa acgtaatcta agagaagttg attatacaag actaaataaa
     3121 gcagaagctg aaagaaaagt agcttatagc aacatagaaa aactgatgcc attctacaat
     3181 aaagacctag tagttcacta tggtaacaaa gtagcgacaa cagataaact ttacactaca
     3241 gaattgttag atgttgtgcc gatgaaagat gatgaagtag taacggatat taataataag
     3301 aaaaattcaa taaataaagt tatgttacat ttcaaagata atacagtaga atacctagat
     3361 gtaacattca aagaaaactt cataaacagt caagtaatcg aatacaatgt tacaggaaaa
     3421 gaatatatat tcacaccaga agcatttgtt tcagactata cagcgataac gaataatgta
     3481 ctaagcgact tgcaaaatgt aacacttaac tcagaagcta ctaaaaaagt actaggagca
     3541 gcgaatgatg cagccttaga taacctatac ttagatagac aatttgaaga agttaaagct
     3601 aatatagcag aacacctaag aaaagtatta gcgatggata aatcaatcaa tactacagga
     3661 gacggtgtag ttgaatacgt aagtgagaaa atcaaaaata acaaagaagc atttatgcta
     3721 ggtcttactt atatgaaccg ttggtacgat attaattatg gtaaaatgaa tacaaaagat
     3781 ttatctacgt acaagtttga ctttaacgga aataatgaga cttcaacgtt ggatactatt
     3841 gtcgcattag gaaatagtgg actagataac ctgagagctt caaatactgt aggtttatat
     3901 gcgaataaac ttgcatcggt aaaaggagaa gattcagtct ttgacttcgt agaagcgtat
     3961 agaaaactgt tcttaccaaa caaaacaaat aacgagtggt ttaaagaaaa tacaaaggca
     4021 tatatagtcg aaatgaagtc tgatattgca gaagtacgag aaaaacaaga atcaccaaca
     4081 gccgatagaa aatattcatt aggagtttac gatagaatat cagcaccaag ttgggggcat
     4141 aagagtatgt tattaccact actaacttta cctgaagaat ctgtgtatat ttcatcgaat
     4201 atgtctacac ttgcattcgg ttcgtatgaa agatatcgtg atagtgtgga tggagttatt
     4261 ctttcaggag atgctttacg aacttatgta agaaatagag ttgatatagc agcgaaaagg
     4321 catagagacc attatgatat ttggtacaat cttcttgaca gtgcttcaaa agaaaaactt
     4381 ttccgttctg tgatagttta tgatggattc aatgtaaaag atgagacagg aagaacttat
     4441 tgggcaaggt taacggataa aaacatcggc tctattaaag aattcttcgg acctgttggg
     4501 aaatggtatg agtataatag tagtgcagga gcgtatgcga atggaagttt aacgcacttt
     4561 gtgttagata gattattaga tgcttatgga acgtcggttt atactcatga aatggttcat
     4621 aattctgatt ctgcaatcta ctttgaagga aatggtagac gtgaaggatt gggagcggag
     4681 ttatacgcac ttggtttact gcaatctgta gatagtgtaa attctcatat tttagcttta
     4741 aatacgttat ataaagcaga aaaagatgat ttgaatagat tgcatacata taatccggtg
     4801 gaacgtttcg attcggatga ggcgcttcaa agttatatgc atggatcata tgatgtaatg
     4861 tatacacttg atgcgatgga agcaaaagcg atattagctc aaaataatga tgttaagaaa
     4921 aaatggttta gaaaaataga aaattattac gttcgtgata ctagacataa taaagataca
     4981 catgcaggaa ataaagtccg tccattaaca gatgaagaag tagctaactt aacatcgtta
     5041 aactcattaa tcgacaacga catcataaat agacgtagct atgatgataa tagagaatat
     5101 aaacgaaatg gctactatac tataagtatg ttctctcctg tatacgcagc gctaagcaat
     5161 tcgaaaggtg ctcctggaga tattatgttt agaaaaatag cttatgaatt acttgcggaa
     5221 aaaggttatc acaaaggatt cctaccttat gtttctaatc agtacggagc agaagcattt
     5281 gccagcggaa gcaaaacatt ctcatcatgg catggaagag atgttgcttt agtgacagat
     5341 gatttagtat ttaagaaagt attcaatggt gagtactcat catgggctga tttcaaaaaa
     5401 gcaatgttta aacaacgtat agataaacaa gataatctga aaccaataac aattcaatac
     5461 gaattaggta atcctaatag tacaaaagaa gtaactataa caacggctgc acaaatgcaa
     5521 caattaatta atgaagcggc tgcgaaagat attactaata tagatcgtgc aacgagtcat
     5581 accccagcaa gttgggtgca tttattaaaa caaaaaatct ataatgcata tcttcgcact
     5641 acagatgact ttagaaattc tatatataaa taagattgta gagtttcatt gttgagtagt
     5701 gtttcttgta aggatgagga gtcagatgac aaatcgactc ctttttctta tggatcgatg
     5761 tagagatttg attgaatgca gattgcagga atcatcttca actcatcaac gaccaatggt
     5821 gacaaggtgg atttcaatcc cacagaaaat gttgatttga gaaataactt tgctagtcta
     5881 gtaaaataaa tacaaaacaa tcctagaaga ttttttctgg gattgttttt tgctgagtgg
     5941 gatgcttcaa gttgtctggc ttgactttct tgagggaagt tatataatag ttgtaataat
     6001 taaagttaca ataaaagagg aaatatttat gacatatgaa taccagagcc acatttattt
     6061 agcagaggca gttttaaatg tgaaggattt ggtcagtcaa acagtttttt atcagcagat
     6121 tattggttta gaaatcctat ctcaaacgga tacagaggtc gttctgggac ttggaggaaa
     6181 agccttggta cacttgattc aagcacaaga gggtggagaa gtaagggaac attatggtct
     6241 ttaccatctg gctattcttt tgccgacacg aaaggctttg gcggatgtct tgaagcacct
     6301 gacggattta cagattcctc ttgttggcgg tgcagatcac ggttacagtg aggcccttta
     6361 cttagaggac ttggagggaa atggcattga actctatcga gataagccag tttccacatg
     6421 ggatattcga gaagatggac gtattatcgg ggtgactgaa gtccttgcgg ctcaggatat
     6481 ctatgagttg ggggaaagag tagagccttt tatcctagca gagggtacga gaatggggca
     6541 tattcatctt tctgtcaagg atagtcgaaa gtccagacag ttttatcaaa cggtgttagg
     6601 gctcgaggat aaattcagtg tgcctagtgc tagttggatc gcagctgggg actaccatca
     6661 tcatttagca gtcaacgaat ggggaggaaa aggtctggat ccgcgtaaac aagtcctacc
     6721 aggtttagcc tactatgtca tcgaagtcgc acataaagaa gaactgttaa cgattgccca
     6781 acgagcacaa gaagttgacg caccaatcaa atggatgaca tcgatccaat tggaaatcac
     6841 agactcagat ggcatcgtga cccgtattcg tttagctaga tagatggtat gtgatgaagg
     6901 tagagcatca attgtagaaa gtgctcctta ttctagtcag atacgtggaa aatttgatat
     6961 gatagtaggg aataaggaga agaataatat gactagcgaa taccagaaaa tgatagcagg
     7021 agagttttac cgtccatcag acccagaact gagagcctta gctcaggctt ctcgccaaaa
     7081 acaggccgcc tttaacaagg aagagaaccc cttgaaggga gccgaaatca tcaagacttg
     7141 gtttgcctca accgggaaaa atctttacat caacactcgc ttgatggtgg actacggtgt
     7201 caacatccat ctaggggaaa atttttattc taattggaac ttgaccatgc tggatatctg
     7261 tcccattcgt atcggggaca atgctatgat tggtcctaat tgtcagtttt tgacacccct
     7321 ccatccacta gatccacagg aacgcaattc aggtatcgag tacggaaagc ctatcacaat
     7381 cggagataat ttctggactg gtggtggcgt cattgtcctt cctggagtga cactgggaaa
     7441 taatgtcgtt gcaggagcag gggcagtaat taccaaatct tttggcgaca acgttgtcct
     7501 agctggcaat cctgcgcgcg tgattaagga aatacctgtt aaatagaagt aaaaaggaac
     7561 agctggggtt gtttcttttt tgtaggtttc atcatttttt acccagttca catttaccta
     7621 ctctatctct tagcaagtct gtttcattaa gcaagttcaa agcatctcgt aagtgggatg
     7681 tttttctcct cagttcatca gcttcctcct tgacactcgg tcagattttg atacaatagt
     7741 acaaaattag aggaggcagg ctatgattca gaaacatgcg attcctattt tagagtttga
     7801 tgacaatcct caggcggtta tcatgcccaa tcacgagggg ctggacttgc agttgccaaa
     7861 gaagtgtgtt tatgcatttt taggtgagga gattgaccgc tatgcgaggg aagtaggggc
     7921 gaactgtgtt ggcgaatttg tttctgccac caagacctat ccagtttatg tcgtgaacta
     7981 caaggacgag gagatttgtc tggttcaggc tcctgtcggt tcagctccag cagcccagtt
     8041 tatggattgg ttgattggct atggtgtgga gcagattatc tctactggga cctgtggtgt
     8101 cctagctgat atagaggaaa atgcctttct agtccctgtt cgcgctctgc gagatgaagg
     8161 agccagttac cactatgtgg caccttctcg ttatatggaa atgcagccag aggctattgc
     8221 tgccattgag cgagttttgg atgatagagg gattccttat gaagaagtca tgacctggtc
     8281 cacagatggt ttttaccgag aaacggctga aaaggtggct tatcgtaagg aagaaggctg
     8341 tgctgttgtg gagatggagt gttctgctct tgcggcagta gctcaattgc gtggagttct
     8401 ctggggtgaa ttgttgttca cagcagattc tctagcggac ttggaccagt acgacagtcg
     8461 tgactggggc tcggaagctt ttaataaggc actagaactg agtttagcaa gtgttcacac
     8521 ctttagttgt actggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa
     8581 aaatatgttt aaacgaggtc accttcctct tgtcctaggc atgttgaggt tgggaaaaat
     8641 ctttaaaatc agaaaaacgt atcatatcag gtgatgaaaa ttttgatact atgcgtttta
     8701 tgttggtaag atttagagtg agatgaaatg atactcttcg aaaatctctt caaaccaggt
     8761 cagcttcacc ttgccgtata gatgttactg acttcgtcag ttctatctgc aacctcaaaa
     8821 cagtgttttg agctgacttc gtcagttcta tctgcaacct caaaacagtg ttttgagctg
     8881 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agctgacttc gtcagttcta
     8941 tccacaacct caaaacagtg ttttgagcaa cctgtgacta gctttctaag cgatgccttg
     9001 gttctcattg cctataatca aaaagagaaa ttttctcctg aaaagcatat agagtagctg
     9061 gcgttaaaag ctcctgtctt gcttttttga cctatagtca catctatcaa gtattgttct
     9121 tgcctaagct atcaataaaa aggtggcatt ttttaggctt ggtgttagta gattttgcct
     9181 tatcctatct aagtcatttc gaacttttta tggtacaatg gaaacatgtt attcaaatta
     9241 tctaaggaaa aaatagagct aggcttatct cgtttatcgc cagcccgtcg tatttttttg
     9301 agttttgcct tggtcatttt actaggctct cttcttttga gcttgccctt tgtccaagtt
     9361 gaaagctcac gagcgactta ttttgatcat cttttcactg ctgtctctgc agtctgtgtg
     9421 acaggtctct caacccttcc agtagctcac acctataata tctggggcca aataatctgt
     9481 ttgctcttga ttcagatcgg tggtctaggg ctcatgacct ttattggggt tttctatatc
     9541 cagagcaagc aaaagcttag tcttcgtagc cgtgcaacta ttcaggatag ttttagttat
     9601 ggagaaactc gatctttgag aaagtttgtc tattctattt ttctcacgac ctttttggtt
     9661 gagagcttgg gagctatttt gcttagtttt cgccttattc ctcaacttgg ctggggacgt
     9721 ggtcttttta gttccatttt tctagcgatc tcagccttct gtaatgccgg ttttgataat
     9781 ttagggagca ccagtttatt tgcttttcag accgatttac tggtcaatct ggtgattgca
     9841 ggcttgatta ttacaggcgg ccttggtttt atggtctggt ttgatttggc tggtcatgta
     9901 ggaagaaaga aaaaaggacg tctgcacttt catacgaagc ttgtactatt attgactata
     9961 ggtttgttgt tatttggaac agcaactact ctctttcttg agtggaacaa tgctggaacg
    10021 attggcaatc tccctgttgc cgataaggtt ttagttagct tttttcaaac agtgacgatg
    10081 cgaacagctg gcttttctac gatagattat actcaggctc atcctgtgac tcttttgatt
    10141 tatatcttac agatgtttct aggtggggca cctggaggaa cagctggggg actcaagatt
    10201 acgacatttt ttgtcctctt ggtctttgca cgaagtgagc ttctaggctt gcctcatgcc
    10261 aatgttgcga gacgaacgat cgcgccgcga acggttcaaa aatcctttag tgtctttatt
    10321 atctttttga tgagcttctt gataggattg attctgctag ggataacagc caaaggcaat
    10381 cctcccttta tccacctcgt atttgaaacc atttcagctc ttagtacagt tggtgtaacg
    10441 gcaaatctga ctcctgacct tgggaaattg gctctcagtg ttatcatgcc acttatgttt
    10501 atgggacgaa ttggtccctt gaccttgttt gttagcttgg cagattacca tccagaaaag
    10561 aaagatatga ttcactatat gaaagcagat attagtattg gttaagaaag gaaagagcat
    10621 gtcagatcgt acgattggaa ttttgggctt gggaattttt gggagcagtg tcctagctgc
    10681 cctagccaag caggatatga atattatcgc tattgatgac cacgcagagc gcatcaatca
    10741 gtttgagcca gttttggcgc gtggagtgat tggtgacatc acagatgaag aattattgag
    10801 atcagcaggg attgatacct gcgataccgt tgtagtcgcg acaggtgaaa atctggagtc
    10861 gagtgtgctt gcggttatgc actgtaagag tttgggggta ccgactgtta ttgctaaggt
    10921 caaaagtcag accgctaaga aagtgctaga aaagattgga gctgactcgg ttatctcgcc
    10981 agagtatgaa atggggcagt ctctagcaca gaccattctt ttccataata gtgttgatgt
    11041 ctttcagttg gataaaaatg tgtctatcgt ggagatgaaa attcctcagt cttgggcagg
    11101 tcaaagtctg agtaaattag acctccgtgg caaatacaat ctgaatattt tgggtttccg
    11161 agagcaggaa aattccccat tggatgttga atttggacca gatgacctct tgaaagcaga
    11221 tacctatatt ttggcagtca tcaacaacca gtatttggat accctagtag cattgaattc
    11281 gtaaagaggg atgacccctc ttttttgatg cctaagatgg caaatagaga cagaagcccc
    11341 ttgtcttcta gtaaaagttc ttcaaaggct ggactttatg gtaaaataga aagaagtgac
    11401 aagagagagt aatactcaat gaaaatcaaa gatcaaacta ggaaactagc tacgggctgc
    11461 tcaaaacact gttttgaggt tgcagataga actgacgaag tcagtaacat ctatacggca
    11521 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taagaaaaaa tcagtcccct
    11581 aaaggagtag attatgaagt tattgtctat cgcaatttct agctataatg cagcagccta
    11641 tcttcattac tgtgtggagt cgctagtgat tggctgggac caggtcggaa atttctccaa
    11701 aggccagtat atcatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca
    11761 gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca
    11821 gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga
    11881 ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa
    11941 tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa tgcgagaata
    12001 tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca accgatctgg
    12061 aacagcggag caactggcaa aaaaacgcca attgtggacc tatattcagc agaaaaatcc
    12121 agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt
    12181 gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa
    12241 ttaatataag tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt
    12301 ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta
    12361 tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg
    12421 ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac
    12481 gtgccgatgg gctcaatcca accccaggtc aagtcttacc tgaagagaca tcgggaacga
    12541 aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg
    12601 gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg
    12661 aaacaagccc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caaaaaaatc
    12721 cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat gggacacaag
    12781 caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag
    12841 acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt cctttcactg
    12901 ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc
    12961 tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg
    13021 ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg
    13081 gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc
    13141 aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta
    13201 atctagttgc tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaactg
    13261 tcgaaaaagc tgttaaaga
//
LOCUS       DAVMCG010000047        12280 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVMCG010000047 DAVMCG010000000
VERSION     DAVMCG010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.048"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            40..849
                     /locus_tag="VYP66_001765"
     CDS             40..849
                     /locus_tag="VYP66_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1851269.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            854..1555
                     /locus_tag="VYP66_001766"
     CDS             854..1555
                     /locus_tag="VYP66_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1851270.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1580..2497
                     /locus_tag="VYP66_001767"
     CDS             1580..2497
                     /locus_tag="VYP66_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV1851271.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2525..4066
                     /locus_tag="VYP66_001768"
     CDS             2525..4066
                     /locus_tag="VYP66_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV1851272.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4085..4543
                     /locus_tag="VYP66_001769"
     CDS             4085..4543
                     /locus_tag="VYP66_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1851273.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4545..6767
                     /locus_tag="VYP66_001770"
     CDS             4545..6767
                     /locus_tag="VYP66_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1851274.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6807..7916
                     /locus_tag="VYP66_001771"
     CDS             6807..7916
                     /locus_tag="VYP66_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1851275.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8073..8963
                     /locus_tag="VYP66_001772"
     CDS             8073..8963
                     /locus_tag="VYP66_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1851276.1"
                     /translation="MKIIGIDIGGTTIKADLYDDFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYVLNYSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTSEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            8988..9311
                     /locus_tag="VYP66_001773"
     CDS             8988..9311
                     /locus_tag="VYP66_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851277.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9301..11292
                     /locus_tag="VYP66_001774"
     CDS             9301..11292
                     /locus_tag="VYP66_001774"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV1851278.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11308..11784
                     /locus_tag="VYP66_001775"
     CDS             11308..11784
                     /locus_tag="VYP66_001775"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV1851279.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11818..>12280
                     /locus_tag="VYP66_001776"
     CDS             11818..>12280
                     /locus_tag="VYP66_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851280.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISN"
BASE COUNT         4164 a         1772 c         2431 g         3913 t
ORIGIN      
        1 ataaagaatg taaacgttta cttcaactaa ggagctcata tgttactgca aaaagaacta
       61 attccaatga tagaagctaa cttaccaaat atggcatatg ctgaaaaaga cattgctaaa
      121 ttcttcttaa aacagcaacc tctgaatgat tattcatcta aagcattgtg cgaatacctt
      181 aatgtatcca aagcaacatt gactcgattt gcgaaaaaat gtggttttaa aggttttaga
      241 caattcattt tcaaatacca agagatgatt catgagaaag aaaagttggc attatataca
      301 gaggcaacag aaaaagtttt atccgactat gaggaaatgt tgagaaaaac ttacacggtt
      361 cttgatgaag ttcaacttga gcgtattgct gagatgatag aaactgctga gcgtgtatat
      421 ctctacggta aaggaagttc tgttcttgct ttacaagaaa tgaagatgag atttatgcgt
      481 ctcggagtga ttggtgaagt attatcagac gaggatatga ttttgtggag tagcttacta
      541 cttaatgaaa attgccttgt cattggagca tccatttcag gtcaaactga tattgtacta
      601 gaaggtctac aaaaagctgc agataaaggc gctaaaacag ttttaatgac tacaagaaaa
      661 tttgacgaag aagattgttt ctttgatgaa ctattgttat tagcttcgac cgatcatctc
      721 tcgtatggca atcgcatatc acctcagttt ccaatacttt taattacaga ctgcttattc
      781 tctaattatc tggaaagtcc agagagacaa tattattaca atcaaactat tatccataag
      841 gaggaataat aaaatgagcc aaatttggac taaagaaaaa tttataagcc aagttcaagg
      901 tggagtcatt gtttcttgtc aagctttacc tggtgaagcc ctttataatg aagaatttag
      961 cttgatgcct tttatggcta aagcagcttt agaggcagga gcagtgggca ttcgcgcaaa
     1021 ttctgtgcgt gatattaaag caattcagaa agtagtagat ttaccaataa ttggaattat
     1081 caaaagggat tatccacctc aagaaccata tattactgct acgatgaaag aagtagatga
     1141 acttgtagaa tgcggaacaa cagtcattgc atttgatgca actttaagac caagatatga
     1201 tggcttagtt gtcagtgaat ttatcaaaaa aataaaagaa aaatatccga atcaattgct
     1261 gatggcggat gtaagtaatt tagatgaagg tctctatgca tttaaatcag gcgttgattt
     1321 tgttggtaca acattatcag gttacacaag tacaagtgta caatcagatg agcctgattt
     1381 tgaactaatg aaaaaattgg ctgattttaa tattccggta attgccgaag gaaaaattca
     1441 ttatccagaa caattaaaaa aagcttatag tttaggtgtt accagtgtag tcattggtgg
     1501 agcgattaca cgtccaaaag aaattgctca gcgatttatt aatgtcatca aataaaaaac
     1561 aatataaagg agaaatctga tgaaagattt aactaaatac aaaggcgtta tccctgcatt
     1621 ttatgcttgc tatgatgaaa atggtgaaat tagccaagat cgtgtaaaat ctctggtaca
     1681 atatttcatt gacaaaggtg taaaaggtat ctatgtaaat ggttcttcag gtgaatgtat
     1741 ttaccaaagt gtagaagatc gtaaacaaat tattgaagct gttatggaag ttgctaaagg
     1801 taaattaaca gttatcaacc atattgcatg taataacacg aaagatagta tcgaattggc
     1861 aaaacattca gaaagtgttg gagtcgatgc tattgcagct atcccaccta tttatttcaa
     1921 attgccagag tattcaatcg cagcatattg gaatgcaatg agtgaagctg cgtcaaatac
     1981 agattttatt atctataata ttccacaatt ggcaggggtt gcgttgactg gtagtttgta
     2041 tgcaacaatg cgtcaaaatc ctcgtgtgat tggagttaaa aattcttcta tgcctgtaca
     2101 agatattcaa atgtttgtag ctgcaggtgg agaagattac attgtattca atggtccaga
     2161 tgaacaatat cttggtggtc gcttgatggg agcagaagct ggtattggtg gtacttatgg
     2221 cgttatgcca gatttgttct tgaaattgga aagtttgatt caagaacgag atttagatac
     2281 agctaaaaaa cttcaatatg ctatcaatga agttatctat aagatgatat caggtaaggc
     2341 aaatatgtat gctgtagcaa aagaagtttt gcgtctaaat gaaaaacttg atttaggttc
     2401 tgttcgtcaa cctttagaag cattggcaga aggtgacttg gaagttgcaa aacaagcagc
     2461 agaacttatt caacaagcac gaaaagaatt tttataataa ataaaatcaa tatggagata
     2521 tgttatgggc acaacaggat ttacaataat tgacttaatt atcttgattg tttatttact
     2581 tgcggtgttg gttgcaggta tctatttctc taaaaaagag atgaaaggaa aagagttctt
     2641 taaaggagat ggttcggttc cttggtatgt tacttcggta tccatttttg ccacaatgct
     2701 cagtccgatt tccttcttgg gactcgctgg tagctcttat gcaggtagct ggattttatg
     2761 gtttgctcaa ttagggatgg tagtagctat tccactgaca attcgtttta tcttacctat
     2821 ctttgcacgg atagacatcg atacggcata tgattacttg gataaacgtt ttaattctaa
     2881 agcacttcgt attatttcag cactcttgtt tattatttat caattgggac gtatgtctat
     2941 cattatgtac ctcccatcag ctggtttatc agtattgaca ggaattgaca tcaatatttt
     3001 gattattttg atgggtgtag ttgcaattgt ttattcttat actggtggtc taaaatccgt
     3061 attatggaca gactttattc aaggtgtgat tctgattagt ggtgtcgttt tagctttatt
     3121 tgtactgatt gctaatatta aaggtggctt tggtgcagta gcagaaacat tagcaaacgg
     3181 gaaattcctt gctgcaaatg aaaaactttt cgatcctaac ttgctttcaa actccatctt
     3241 tttaattgtg atgggttcag gctttacaat cttgtcttcc tatgcttcat ctcaagattt
     3301 ggttcaacgt tttactacaa cacaaaatat taagaaactt aataagatgt tgttcacaaa
     3361 cggtgttttg tcacttgcaa ctgcaacagt cttttacttg attggtacag gcttgtacgt
     3421 attctatcaa gtacaaaatg cagatagtgc agctagcaat atccctcaag accaaatctt
     3481 tatgtacttt attgcatacc agttaccagt aggtatcaca ggtttgatct tggcagcgat
     3541 ttatgcagca tctcaatcaa ctatttcaac aggtttgaac tctgttgcaa cttcatggac
     3601 attggatatt caagatgtca tttctaaaaa tatgtcagac aatcgtcgta cgaaaattgc
     3661 acaattcgta tctctagcag taggtttatt ctcaattggt gtttccattg tcatggctca
     3721 ctcagatatt aaatctgcat acgaatggtt caatagtttc atgggacttg tacttggtct
     3781 acttggtggt gtatttattc ttggatttgt ttctaaaaaa gcaaataaac aaggtgctta
     3841 tgcagcgctg attgtatcaa ccatcgtcat ggtatttatt aaatacttcc ttcctccaac
     3901 agctgttagc tactgggcat attcattgat ttcaatctct gtatcagtag tttcaggtta
     3961 tattgtatct gttcttactg gaaataaagt atctgcacct aaatatacaa cgattcatga
     4021 tattacagaa attaaagcgg attcaagttg ggaagttcgt cactaataga aaagagaaaa
     4081 taatatgatt atttctgaac aatctgattt taaacgatat gcttctgtca ataaatattt
     4141 ttcaaaagtc tgtgattttt tagaaaatac aaatttgaca gatttagttg atggaaaaat
     4201 tgatattgac ggggaaaatg tttttgcaaa ttgtatgact tatctagctg atggagttcc
     4261 aggagatatt tttgaaactc ataagaaata tttagatatt catattgttg ttgaaaatac
     4321 tgaaaaaatg gcagtaactt ccccagttcg tgcccagtca cgtgtacctt ttagcgaaga
     4381 gaaggatatt gctttttacg atagcaaaga ctatcaaatt gttgaattgc ttccagggaa
     4441 tatgttggtg acttttgaag aagatcttca ccaaccaaag attcattgca atgatgaaac
     4501 tgttaaaaaa cttgttatca aagttttaaa cgaggaaaaa taaaatgaaa aaaaatatta
     4561 aacaatatgt aaccttaggt actgtagtgg tattatcagc atttgttgct aactcagttg
     4621 cagctcagga gactgaaact tctgaagtat caacaccaaa gttggtgcaa cctgttgcac
     4681 caacgactcc gatttcggaa gtacaaccta catcggataa ctcttcggaa gttactgtac
     4741 aacctcgaac agttgaaact actgttaagg atccatcttc tacagcggaa gaaactcctg
     4801 tcttagaaaa aaataatgtt actttaacag ggggcggaga aaatgttact aaagagttaa
     4861 aggataaatt tactagcggt gactttactg tagtgattaa gtacaatcag tcaagtgaga
     4921 aaggcttaca agctctgttt ggaatatcta attccaaacc cggtcaacaa aatagttatg
     4981 tagatgtgtt ccttagagac aatggtgagt tggggatgga agcgcgtgat acttcttcca
     5041 ataaaaataa cctagtatcc agacctgctt cagtttgggg taagtacaaa caagaggctg
     5101 tgactaacac tgttgcagta gtagcagatt cagtcaaaaa aacatattct ttatacgcaa
     5161 atggtacaaa agtagtagaa aagaaagtgg ataatttcct aaacatcaag gatattaaag
     5221 gtattgatta ctatatgctt gggggagtga aacgtgcagg aaaaacggcg tttggtttta
     5281 acggaacact agaaaatatc aaattcttta atagtgcatt ggatgaagaa actgttaaaa
     5341 agatgacaac aaacgctgtt actggacatt taatttatac ggctaatgat acaacaggtt
     5401 ctaactattt ccgtattcca gttctgtata cttttagcaa tggtcgggta ttttcaagca
     5461 ttgacgctcg ttacggtgga actcatgatt tcttgaataa aattaatatt gctacaagtt
     5521 atagtgatga taatggtaag acatggacta aaccaaaatt aacattggca ttcgatgatt
     5581 ttgcgccagt accattagaa tggcctcgtg aagttggtgg acgtgactta caaatcagcg
     5641 gtggtgcaac ctatattgac tctgttattg ttgaaaaaaa gaacaaacaa gtactcatgt
     5701 ttgctgatgt gatgcctgct ggagtaagtt ttagagaagc aactagaaaa gattcaggtt
     5761 ataaacaaat tgatggtaat tattacctta aattaaggaa acaaggtgat actgattaca
     5821 attatactat tcgtgagaat ggtactgtat acgacgatcg taccaacaga ccaactgaat
     5881 tttcagtaga taaaaatttc ggtattaaac aaaatggtaa ttatttgacg gtagagcaat
     5941 attcggtttc atttgaaaat aataaaaaga ctgaatatcg taatgggact aaagtccata
     6001 tgaatatctt ctacaaagat gcattgttta aagtagtgcc aacgaactat attgcatata
     6061 tttctagcaa tgatcatggc gaatcttggt ctgcaccaac tttattacct cctataatgg
     6121 gacttaatcg gaatgcgcca tatttaggtc ctggacgtgg aatcattgaa agctcaactg
     6181 gacgtattct tattccgtct tacactggta aagagtctgc gttcatttat agtgacgata
     6241 atggagcatc ttggaaagtt aaagtagtgc cacttccttc tagttggtca gcagaagcac
     6301 aatttgtaga attgagtcca ggagtaattc aagcatatat gcgtacaaat aatggtaaaa
     6361 ttgcatattt aacaagtaaa gacgcaggta ctacttggag tgcaccggaa tatttgaaat
     6421 ttgtttcaaa tccaagttat ggaacacaat tatcaatcat caattatagc caattgattg
     6481 atggtaaaaa ggctgtcatt ttaagtactc caaactccac aaatggtcgt aaacacggac
     6541 aaatttggat tggtctaatt aatgatgata atacaattga ttggcgttat catcacgacg
     6601 ttgattatag taactatgga tactcatatt caacattgac agagttacca aatcatgaaa
     6661 ttggattgat gtttgaaaaa tttgattcat ggtctcgtaa tgaacttcat atgaaaaatg
     6721 ttgtaccata tataacattt aagattgaag atctgaaaaa gaattaaagc tgaaatttga
     6781 aaatatataa aaagaggata aaaattatgg taaattacgg tattgttgga gctggatatt
     6841 ttggagctga tttagctcgc tcaatgaaca aaattgaaga tgcaaaagtg gttgcggtat
     6901 ttgacccaaa tcatggagaa gaagttgctc aagagttggg atcagatgtt tgtgcaagtt
     6961 tagatgaact tgtagcacgt gaagatattg attgtgtgat cgtagcttca cctagctacc
     7021 ttcaccgtga accagttgtg aaagctgctc aacatggcaa acacgtattt tgtgaaaagc
     7081 caattgcatt gtcttatgaa gattgtaaag ccatggttga cgcatgtaaa gaaaataatg
     7141 tcatctttat ggctggtcac atcatgaact tctttaacgg tgtacaccat gctaaagaat
     7201 tgattactca aggtaaaatc ggtaaagttc tttattgcca tgccgctcgt acaggttggg
     7261 aagaacaaca accaactgta tcatggaaga aacttcgttc tcaatctgga ggacatttgt
     7321 accaccatat tcatgaatta gattgcattc agttcatcat gggaggactt cctgaaaaag
     7381 cgacaatggt aggaggcaat gtatatcata aaggtgaaaa ctttggtgat gaagatgata
     7441 tgctcattgt aaacctagaa tactctgatg atcgttatgc tgttttggaa tatggtaatg
     7501 ctttccgttg gggtgaacac tacgtcttga ttcaaggaac tgaaggagct atcaaacttg
     7561 acttgttcaa tactggaggt actcttcgtg ttaaaggtga aggagaatca cacttcttag
     7621 tacatgaaac tcaagaggaa gatgatgacc gtacagctat ctataccggt cgtggtatgg
     7681 atggagcaat tgcgtacggt aaaccaggag tacgttgccc attatggtta caaacatgta
     7741 ttgataaaga aatggaatat ctacatgaca tcattaaagg tggagaaatt acagaagaat
     7801 atgaaaaact tctcaatggt gtagctgctt tagaatcaat cgctaccgct gatgcatgta
     7861 ctttatcagt taaagaagat cgaaaagtaa gtctttcaga aatcacaaat gcttaactat
     7921 tgtaaaacag aatagtaaat tcttgtcatt atataatttc taaagttctg tgatacaact
     7981 cattgaataa agaaatagag atgggactgg gataatgccc agtcccattt tttatcaaaa
     8041 agtaatgaga tcaaaaatgt gggagtgatg aaatgaagat tatagggatc gatattggcg
     8101 gaacaacaat taaggcagat ttatacgatg attttggaac gagtttaaat cagttcaaag
     8161 agatagaaac aattattgac tatgatttgg gaacgaacca gatattaaat caggtctgtg
     8221 atttaattgg tgagtatgtt ttaaattatt caattgatgg tgttgggatt tccactgctg
     8281 gagttgttaa tgctaataca ggagaaatca tctatgcagg ctatacaata ccagggtata
     8341 tcggagtaaa ctttacttcc gaaatagaaa aacgttttgg gttgtctact tttgttgaaa
     8401 atgatgttaa ttgtgctgca ttaggtgaat tgtggaaggg acaagccaaa gataagaaaa
     8461 atgtagtaat ggttactatt ggaacaggta taggaggcag tattattgtc aacggacaaa
     8521 ttgttaacgg atttaactat actgctggtg aagtaggtta tattcctgta ggtaattcgg
     8581 attggcaaag taaagcctca acaaccgcat tgattcattt atatcaaaaa aagagcttga
     8641 aaactaatca aactggacgt actttcttca ctgatttaag atctggagat aaagttgctg
     8701 aagaaacttt tgaaattttt gtagaaaatc taacaaaagg tttattaacg atttcttatc
     8761 tacttaatcc agaaattctc atattaggag gtgggattct ggatagtaag gatattttgt
     8821 tacctgaaat tcaaagttct ttagctaaaa atgcaatgga taataggttt ttacctaaaa
     8881 atcttgtggc agctacatta ggaaatgaag ctggtcgtat aggagctgta aaaaatttct
     8941 tagatagaat ttctaataaa tagtatgtaa gataaggagg tgtcacaatg actaactctg
     9001 tattttcgac aatgcaagat attgagaatg ttgcaaccga tattataaaa tcatatgata
     9061 atgagattta tacttataaa gctgtttccc aagaagaatt ggaaaaacta gaaaaaagtt
     9121 atgatgaaaa aagtcacgaa gaattagttt caatagaaag caatttagaa atgaaacaac
     9181 agaaccttat tgatgaggtt aataaaacaa tcaaggaaaa tgatgcaaat attcagtata
     9241 tttcatcaag taggagagga gaatttgtag aaaaaattat tggtagggtg gtagaaaaat
     9301 atggccatta gtcagatgaa aagaatctct ctactatttt ctaaaagtag tcttgatgat
     9361 gttttaaaaa ctattcaaga actagagtca gtgcagttcc gtgatttaaa ggttcaggat
     9421 aactggtcag aagctctaga aaaagatgaa gttgtatttc caactattca aatttttcat
     9481 acttctaatt ccaatcatgg ggttattgag ggaaatgatg ccttgactta tttgatgaat
     9541 caacaacaac atttagaagc aactgtagag aaattacaag aatacctacc gaaagaaaac
     9601 acgtttaaat tattgcagca acctccgata actacctctt atgaagaatt agagaaattt
     9661 ggtaaagcta atgttgctga gggtgttctt aaaaaagtga atcatcaaat taacagagtt
     9721 catgaattag aaagacacat tcaaagtaat aatgaggaaa tagagcgatt aataaagtgg
     9781 gaaaaattag aaattgttcc tgcgaattta gaacaatttt ctttctgtaa aggaaaagtc
     9841 ggaacaattc caaggactga agataatcgc ttatacaata gtcttttaga aaacaatatt
     9901 gaagttcaag aaatattttc taatgataga gagtacggtg ttgttgtttt ctatcagtct
     9961 agttactcta tagattttga tgaatactta tttgaaccat ttgattattc tagaaaggaa
    10021 ttaccgaagc agcgagtagt agatttagat caagaaaaca tgcagttaat aactgaaaaa
    10081 gagaatatta tcgcatcgtt gcaagattca aagaaatatt tgatagattt acaatggcaa
    10141 atagactata ttttatctat ctatgctcgt caaatctcta agaataactt tttgtgcact
    10201 ccgcatctag ttgcattaga aggatggata gaagaaactc gtattttata ttttataaaa
    10261 gttatggatg agcattttgg acattctatt tatatttatg aatcggaaac attgacggat
    10321 aatcaagatg aaatacctat caaattaacg aatcattctt taattgaacc atttgaatta
    10381 ttgacagaaa tgtatgctct gcccaaatat tatgagaaag atcctacacc tgtattagca
    10441 ccattttact ttacattttt tggaatgatg gttgctgatt taggctatgg tttactattg
    10501 tttttaggaa caatgttagc attaaaaatt tttcatctac cttcagcaac taagagattt
    10561 ttaaaattct ttaatatatt aggggtagcc gttgcaattt ggggtggaat ctatggctca
    10621 ttttttggat atgagttgcc atttcatctg atatctacaa cctctgatgt catgactata
    10681 ttagtagtgt cagttgtgtt tgggtttatt acagtatttg caggtttgtt agcttcagga
    10741 ctacaaaaag taagaatgaa gaaatatgca gaagcatata attcaggatt tgcgtggtgt
    10801 gttattctgc ttggcttgtt atttattgct gttggaatgt tgatgcctga tatgagaccg
    10861 ttatttgtat tagggaaatg ggtatctatt tttaatgctg tggggatttt gattgtttct
    10921 attattcaaa ccaaaagctt gtcaggtatt ggagcaggat tgtttaatct atataacatt
    10981 tcatcttata taggtgattt agttagtttc actcgattga tggcattagg attatctgga
    11041 gcaagtatag catcagcttt caatttaatt gttggtttgt ttccgggaat attggctaaa
    11101 ctgacaattg gattagtatt attcattctt ttacatgcga tcaatatttt tctatcgtta
    11161 ctatcaggat atgttcatgg agcacgtctg atatttgttg aattttttgg taagttttat
    11221 gagggtggag gaaaaccatt tcaacctttg aaggcttctg agaaatatat taaggttatt
    11281 acaaagaatt aatggaggat atatataatg gaacatttag caacttattt ttcaacctat
    11341 ggaggagctt tcttcgctgc attgggaatt gtattggcgg ttggattaag cggtatgggg
    11401 tctgcttatg gagttggtaa ggctgggcaa tctgccgcag ctttactgaa agaacagcct
    11461 gaaaagtttg cctcagcttt gatattgcaa ctattgcccg gaacacaagg attatatggt
    11521 tttgttattg gaattttgat ttggttgcaa ttaactccag aacttccttt ggaaaaaggc
    11581 gttgcttatt tctttgtagc tcttccaatt gctattgtag gatacttttc agctaagcat
    11641 caaggaaatg tagcagtagc gggaatgcaa atcttggcta aaagaccaaa agaattcatg
    11701 aagggagcaa ttttagctgc catggtagaa acctatgcaa ttcttgcttt tgtcgtatca
    11761 ttcattttga cccttcgtgt ataagaaata aatttgcaat tcaaaggagg tgtctaaatg
    11821 agcaatttag aaaacttacg agagtctgtt attgaacaag ctcatgaaaa agggcgtatg
    11881 aaattattgg attccaaaaa gaagattgat gatgaatttg aaatgcaaaa gtcgctcatt
    11941 ataaagaaaa aagaagctga acatgaacga aagttaaaag aattgcaaca gaaatatcaa
    12001 ataatttttc aacaattaaa aaataaggaa cgccaatcaa cgttagtatc aaaacagaaa
    12061 atattaaaag aactttttca atctgcttta ctagaaatgg aatcttggag tgcagataaa
    12121 gaaatggagt tcatctatcg aattctggaa cgatattcac aacaagaggt catagtaacc
    12181 tttggggaac ggactttagc taaattcaat ttggaacaat tagagaaatt gaaattctct
    12241 tttccaaatt atttatttag tgaacaacct atctcaaatg
//
LOCUS       DAVMCG010000048        12228 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVMCG010000048 DAVMCG010000000
VERSION     DAVMCG010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12228
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.049"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(51..1253)
                     /gene="rpsA"
                     /locus_tag="VYP66_001777"
     CDS             complement(51..1253)
                     /gene="rpsA"
                     /locus_tag="VYP66_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1851281.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(1415..1486)
                     /locus_tag="VYP66_001778"
     tRNA            complement(1415..1486)
                     /locus_tag="VYP66_001778"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1452..1454),aa:Gln,seq:ttg)
     gene            complement(1496..1576)
                     /locus_tag="VYP66_001779"
     tRNA            complement(1496..1576)
                     /locus_tag="VYP66_001779"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1540..1542),aa:Tyr,seq:gta)
     gene            complement(1626..1856)
                     /locus_tag="VYP66_001780"
     CDS             complement(1626..1856)
                     /locus_tag="VYP66_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1851282.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEIFIENYNLAK"
     gene            complement(2024..2668)
                     /gene="pcp"
                     /locus_tag="VYP66_001781"
     CDS             complement(2024..2668)
                     /gene="pcp"
                     /locus_tag="VYP66_001781"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1851283.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(2683..3606)
                     /locus_tag="VYP66_001782"
     CDS             complement(2683..3606)
                     /locus_tag="VYP66_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1851284.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(3603..4292)
                     /locus_tag="VYP66_001783"
     CDS             complement(3603..4292)
                     /locus_tag="VYP66_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1851285.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(4357..5061)
                     /locus_tag="VYP66_001784"
     CDS             complement(4357..5061)
                     /locus_tag="VYP66_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1851286.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(5117..6139)
                     /locus_tag="VYP66_001785"
     CDS             complement(5117..6139)
                     /locus_tag="VYP66_001785"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1851287.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(6271..8742)
                     /gene="parC"
                     /locus_tag="VYP66_001786"
     CDS             complement(6271..8742)
                     /gene="parC"
                     /locus_tag="VYP66_001786"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1851288.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(9162..11105)
                     /gene="parE"
                     /locus_tag="VYP66_001787"
     CDS             complement(9162..11105)
                     /gene="parE"
                     /locus_tag="VYP66_001787"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1851289.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            11241..11882
                     /gene="plsY"
                     /locus_tag="VYP66_001788"
     CDS             11241..11882
                     /gene="plsY"
                     /locus_tag="VYP66_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1851290.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(11925..>12228)
                     /locus_tag="VYP66_001789"
     CDS             complement(11925..>12228)
                     /locus_tag="VYP66_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1851291.1"
                     /translation="TILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSPDNGMMESF
                     FGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         3515 a         2770 c         2159 g         3784 t
ORIGIN      
        1 gaaaaatccc ttgtttagta aacaaaggat tttgtgaatt ttcaatttga ttaaagttcg
       61 atatcaccaa acaaatcagc cattgaaaat cctgtttgtg tttctggaag ttcgaaatca
      121 cgcttttctt gacgtcttgg acgacgtgga cgagcagcac gtttttcttc tttttgtcct
      181 tcttcttggg ctggacgttc ttcaagagct ttaatagaaa gtgacacgcg ttctgcatct
      241 gcgttaactt caagaacttt aacttgaact tcttgaccaa ctttaagagc ttcttttgga
      301 ttttcaatcc gtttgtgtga aatttgtgat acgtgaacaa gtccatcgat acctggcaat
      361 acttcaacaa atgcaccgaa gtcagtcaaa cgtttaactg ttccttctac tacatcacct
      421 ttagccaatt tttgctcaac gccatcccat ggtcctggta ctgttgcttt aagtgaaagt
      481 gatacacgtc cttcttcttc gttaagatca aggattttca cttcaatttc ttcaccaaca
      541 gttacaactg attttggtga tacgttacgt tcatgtgaca attcagtcaa gtgaaccaat
      601 ccgtcaacac caccaaggtc gatgaaagcg ccgaagcttg tgatacgagc aactttacca
      661 gttacaacat caccaacagc caatttaccg aatacttcag cgcgagctgc tgcagtagct
      721 gcttcaacaa cttcacgacg tgaaaggatg aagcggtttt ctttagcgtt aacttctttg
      781 attttagtat caaattcttg acctacaaaa cgctcagcgt tacgtacgaa acgagtatcc
      841 aacattgaag ctgggataaa tccacgaaca ccttcaaatt ctactgaaag tccaccttta
      901 acggcacgcg ttcctttaac agtaacaact tcttcttcgc gaccaacaag tttgtcccat
      961 gctttgcgag cttcaaggcg ttttttagat acaaggtatg taactgtatc agtatcttta
     1021 ccaactactt gacgaagtac aagaacatcc aatacttctc ctactttaac aaagtcattg
     1081 atatctgcat cacgatcgtt tgtcaattcg cgaagagtca agacaccttc aacaccagtt
     1141 ccagagattg caacgttagc ttgagtcgca tcaactgtca atacttcagc actaacaaca
     1201 tcaccagtct caacttgact aacgctattt agcaaatctt caaattcgtt catctaaaaa
     1261 atcctccaac aatcaagttt ttcttaaact tgacatactt ataatttttt tcctaagcac
     1321 ccgcaaggac atgttcatat cattcacgtc tttcaattat aaaaataaaa taccctaaga
     1381 tattttgctt tctatcttga ttattaccta agaactgggg tagctggatt cgaaccaacg
     1441 catgagggag tcaaagtccc ttgccttacc gcttggctat accccattaa tgaaatggag
     1501 agagagggat tcgaaccccc gaacccgaag gagcggattt acagtccgcc gcgtttagcc
     1561 tcttcgctat ctctcctaca atcaacatgg actattatat catgaaaatt tcaaaaaaac
     1621 aagacttatt ttgctaaatt ataattttca ataaaaattt ccacagcttt ttccaatttt
     1681 ttataaaaac tatcgacatt cccattcttt ataatggcaa attgtccgtc taattcggca
     1741 atttctccga taactttttt accgatagtc aatgtataac cttcaaaact gtctttacca
     1801 acattaactt tggcatccgc tacttgaatt tcgatttttt tatctttctt gctcatttca
     1861 tacctctctt cactttttct attttacaag aaaatcctaa aactagcaag aaaaaactct
     1921 atatcaggct tctctgatat agagttttat gtaaacaacc tcaattgatt tagcatagtt
     1981 aatagttagt aaacaagcat aattgactat cctttttagg ttatcagtga gtctcaccgc
     2041 ctactaactg caaatcctta tctttgtagt ctacaatagc ttcaatagct acctctatgc
     2101 ctcttacaat atcacataga ctcattcctg cagtattcgg cttatttact acttgttcca
     2161 tcatatatgg aatatgcatg aaacctgctc tcatattagg gaatttttta tccactaaat
     2221 aaagagcttg gtacatcaaa tgattgcaaa caaaggttcc tgcactattg gatacaactg
     2281 ccggaagtcc ctgttttttg atagcttgta ccatcgcttt gataggtaaa ctactaaaat
     2341 aggccgatgc tccatcaata cgaatcggtg tatcaattgg ttgattgcct tcgttatcag
     2401 gtatgcgagc atcatcttga ttaatagcca ctcgttcagg tgttaagccg gtcctgccgc
     2461 ctgcttgtcc aatacaaagt acagcatctg gttgatatcg taatatttct gcctctaaaa
     2521 cttctgacga cttataaaaa accgttggaa tttctaccca gcgaacttca gccccattaa
     2581 tctcagatgg taataatttt acagcctcca aagctggatt aatcttttca cctccaaaag
     2641 gattaaaacc tgtaaccaat attttcattt tattttcctt tactaaaatg cgagaaagta
     2701 cattaagaat atgtgaataa caatcattac tagagcaaca cctgcttgag cctttataac
     2761 gccattctga tctttcatat ccatcaatgc tgctggtaga gcgttaaaat tagcagccat
     2821 tggggtcaat aaggtcccac aataacctgc tgtcatggca agagcaccag ccacaattgg
     2881 attagctccc agagcaaata caaagggaac tccaacacct gctgtaataa cggtgaatgc
     2941 tgcaaaagca tttcccataa tcattgtgaa tagaaccatt ccaagaacat aagccaaaac
     3001 tcctataaag cgactatctg aaggaacaat accgctaatc agatgagaga taacatcacc
     3061 aacacctgct acagtaaaaa tagcccccaa agcccctaat aattgaggaa caatcccact
     3121 tgttgaaact tgctgagtca ttcgattatt ttctgataac agactcttag ggtgactatt
     3181 ggtaatcaca agaacagaaa ttgtagcaaa caaggcggca aggctaatcg aaatcttgct
     3241 aaattctgga atcatttgcg ctaagaccaa cgcaagtatt gccatcagca taactggaat
     3301 aaaaatttta tttttcaacc tgttagattc aatattggct ttcatttcat ctaaggatgg
     3361 caaggttccg atacggactt gcttaaacaa tgttaacagc gataatagga ttacaataat
     3421 accaatactc atatttggca tataggaacc acctataaac gtaatagaca atagagtcca
     3481 aaatgcagat gtcccaagtc gaactgggtt tgttttatct ttataactac aataggctgt
     3541 atggagaaat tgacaaccaa tcacaatata ggtcaactct aatagttgct ttgccaactc
     3601 tgtcattttt gttctcctcc cctagtcttt tttgatatca attttttatc aaataaataa
     3661 ttgtaaatcc ccactacaat aagtgttata acagcaacaa taatagatgt agaagcaatc
     3721 cctgcataat tgctttcata gcctaactga tctaatgttc cccctatcaa gaggactccc
     3781 ccagcaccta caaacgtatt ttgagcaaag aaatttccaa aattttcatt cgcagccgca
     3841 cgcgctttta ttgtctcatc ttcaacctct gttaactttc tacctaattg agactctgca
     3901 gctgcttctc ccataggttg aaccaaaggt ctgacaaact gagggtgtcc tcctagacga
     3961 attgaaaaga aaccagctaa ctctcgaata aagaaataaa ctgtatagaa gtttccaact
     4021 gtcagacctt taatctttcg aatcaaatcg attgatcgtt gcttgagtcc aaaggtttct
     4081 gacagcccca caagaggcaa ggtaaccata aaaatcgtga gcactcgctg attgctaaat
     4141 tcttttccca aaatctccaa aaattcaacg agagaaacac ctgaaactaa agctgtaacc
     4201 aaaccagcta agactactgt tgcaattgta tcaaatttta aaataaaacc cacaacaatg
     4261 attgctattc ctattaatct aatccactcc atatcaaact cctttatatt caaaatgaca
     4321 gtattttaaa aattttatca agatcaatac cattccttat ttaatgtatt tttctagttc
     4381 tttttggtat ttgctattgg attccaattt ttctttttgc cattttttaa aaacctcgtt
     4441 atattctttt gttgtaacaa tatctttttg caatttcatt cctttaaaga tatatggttc
     4501 ccccttaata ccaacttgtg agtatggttt tgagaatggt actacgttac ttacaactgg
     4561 agaaccacca gatgaagctg ttggcatcaa taatgaacta tctgtcgacc aagcttgagc
     4621 tttggcatat ttttcatatc tcttctctag gtcagtggtc tcagaaacag catcttctaa
     4681 caatttctta tatttatcca aaccaggttt agctacaaca tccttatctt ttcctttcgt
     4741 aatgccaagg tgtttcatgg cagaaccaga ttttggatcc ataatattca agtaagacgc
     4801 tggatcttga tagcttggag cccatcctgt actattcaaa tcatagtctt tttgagaagg
     4861 agcaacattg ccgtatttat cattttccat caaaccatca ataacatttc caataacgtc
     4921 tgtcgtcgat gttcgagtcg ctatactgta gcccaatgat gctggatcta ctgcatagac
     4981 ataagaaaat gttgtcggtg catctgcttc tttatcagtt tttccacaag ccactaaaat
     5041 agctgacgtg ctcaggacca ctcctgctgt taagagccgc tttttctatt tcataaaaaa
     5101 tctcctttgg tttattttaa tctactttta caatccaacc ttctggcgct tcaatatcgc
     5161 caaactgaat acccgtcaat tcattatata atttacgcgt cacaggacct acttctgttt
     5221 cactatagaa tacatggaaa tcatcaccat gttgaatacc tccaattgga gaaataaccg
     5281 ctgctgtacc acaggcacct gcctctacaa aacggtcaag attatcaatt ggaacatcac
     5341 cctcaatagg agttaatccc aagcgatgtt ctgccaaata aagcaaggaa tacttggtaa
     5401 tagatggcaa gatagatgga ctcaatggtg ttacaaattc attatcagct gtaattccaa
     5461 agaagttagc tgatccgact tcttcaatct ttgtatgagt tgatgggtcc agatagataa
     5521 catctgagaa atgacgtgac ttggccattt ttcctggtaa gagacttgca gcatagtttc
     5581 caccaacctt agccgcacct gtaccatttg gtgctgcacg gtcgtactca tcctgaatca
     5641 agaagttggt tgggaccaaa ccacctttaa agtaatttcc aactggcata gcaaagatgg
     5701 tgaaaatgta ttcttctgcc ggttttaccc cgataatatc tccgacacca atcaaaagag
     5761 ggcgaagata taaggttcca cctattccgt atggtggtac gtattcttca ttcgcacgga
     5821 caactgcttt acaagcttct acaaacatgt ctgtcggaac ttgtggcatc aagagacggt
     5881 cacatgtacg ttgcaggcgt ttagcatttt catcaggacg gaacagttga acactgccat
     5941 ccttagtacg ataagctttc aaaccttcaa atgcttgttg tccatagtga agacttggag
     6001 aagactctga aatatgcaaa gttgcatcct ctgtaagctc tccttgatcc cattgtccat
     6061 ttttgaaatg agcaagatag cgataaggta atttcatata ggaaaaaccg aggttttccc
     6121 aatcaatcgt tactgtcata ttccactcct tattctaaaa acctatttct tatattctac
     6181 actatttttc taaaatagca agtatatttt gtaattttca gaaaatttct ccaataaaaa
     6241 ccagctctta gaactgattc ttcatttcac ttatttatct tcagtaacta cttcctgaag
     6301 ataagcgtca aaaacttctt catctgaaat cgtgtcagaa atgaagcttc cattgctagt
     6361 gcgttctgac aagttcaagt cttgcaatcg gctttcatag attgttcctt tattggattg
     6421 gacaagcaga gtttggtcgt tcacatccac ttccgtactg aagaaatcgc caacaaatcc
     6481 ttgctctgca actgctcctg ccaagaagac acgatgcggt ttgtttttca actcacgcaa
     6541 gacttgtaat cctcgtttgg cacggctggt tgctagaatt tcctcaatgg aaacacgttt
     6601 caagcttcca cgctgggtca agaggtagaa ggacgaagta ttacagataa agccagattg
     6661 gaggacatca tcttctttca aattcatagc cttgacacct gctgccttag caccgacaac
     6721 cggaacctct tcgatattga aacgcagggc ataaccattt tgactaacca agacaacatc
     6781 atctagttta atcggagcca ctgctacaat ctgatctgta tcgtctttga gcttagcata
     6841 cttgacagac ttagatctat aggtccgcca tggagtgaat tcttttcgct ctacccgttt
     6901 gatttgacca aggcgagtcg ctgcaaagta ggttgtcgca tcgtcaaact gatccagtac
     6961 ttccacataa aggattgctt cattcgtttc aaagtttgtg atggtttggc tcagatgctc
     7021 tccgatgtcc ttccaacgaa tatctgccaa ctcatggatt ggtctgtaga tgacatttcc
     7081 aagacttgtg aacatcaaga ggtgctgggt tgtcttggca gattgaacaa aaatcaaacg
     7141 gtcatcatca cgcttgccaa tttcttccaa ggtggaagcc gcaaaggaac gtggactggt
     7201 acgcttgatg taacctgcct tggtcacgct gacgtaggta tcttcctcag cgataagact
     7261 agctgtatca atctcaattg ctttcgcagt gtcttctaaa gaactcaaac gaggagttgc
     7321 aaatttcttc ttgacctcac gaagttcttt cttcatgaga ttgtacatag tcctttcatc
     7381 accgataata gccaccagca tagcaatctt ctcacgaagc tctgcttctt cttcctgcaa
     7441 gacaaccaca tcggtattgg tcaaacggta cagttgcaaa gttacgatag cctcagcctg
     7501 ttcttccgta aaatcatagc taactttgag gttttccttg gcgtccgcct tattctcaga
     7561 agcacggata agagcaatga cttcatccaa aatcgaaatc acacgaatca aaccttcgac
     7621 gatatggaga cgtttctcag ccttttcttt gtcaaagcgt gaacgcgcca aaatcacttc
     7681 tcgacggtga gcgatgtagc tagacaggat tggaacaatc ccaacctgac gaggtgtgaa
     7741 attgtcaatc gccaccatat taaagttgta gttgatttgt aggtcggtgt acttaaataa
     7801 gtagttgaga acaagctcag tattagcgtc tttcttaagt tcgatagcga tacgaagacc
     7861 atcacggtca gactcatcac gaacctcagc aatcccagct accttgttat taacacgaac
     7921 atcatcgatt ttcttgacta gattggcctt attgatttca taaggaatct cagtaataac
     7981 gatttgttcc ttaccacctt ttagcttttc aatttcagtc ttggaacgaa caaccacgcg
     8041 ccctttccca gtctcataag ctttcttgat ttcatcacga ccctgaataa tagcccctgt
     8101 agggaagtct ggtccaggca agaattccat gagtttatca atctttgcag ttgggtggtc
     8161 aatcatgtaa actgcagcat ctatgacctc agctaaatta tggggaggaa tgtctgtggc
     8221 ataaccagcc gaaatcccag tcgaaccatt gaccaagagg tttggaaagg ctgctggcaa
     8281 gaccgttggt tctttctccg tatcgtcaaa gttccatgca aaaggaactg tctttttctc
     8341 gatatcctga agaaggtagc ctgcaatttc agacaaacgt gcctcagtat aacgcatagc
     8401 cgcaggagga tctccgtcca tagaaccgtt attaccgtgc atttcaacta gaatctcacg
     8461 atttttccag ttctgtgaca tacgaaccat ggcgtcatag atagaagaat ccccgtgtgg
     8521 gtggaaattc cccatgatgt tcccgactga cttggccgac ttacggtagc tcttgtcaaa
     8581 agtattgcta tccttattca tagaataaag aatacggcgc tgaaccggct tcaacccatc
     8641 acgaatatct ggcaaagccc ggtcttgaat aatgtacttg gagtagcgac caaagcgctc
     8701 tcccatgatg tcctccaggg acatgttttg aatgttagac ataagataca aagcccataa
     8761 aataccaagt gaaaatagaa aattcttgaa gtaagcaaac tcacaagaga atttatcttt
     8821 ttcacacagt atctagggcg tgttcaactc ctttcaaaga atgtagagta ggtttttatg
     8881 cagtaaaaga tattttacgg gaattcgtcc cgtgttcagt tacgataagt aaccaaacta
     8941 tcctgtttgt atttttcaat atgaaaatat ggttttccaa aattagtctt agtttgtgtc
     9001 ttagccgctc ccttaaacgc ctctttgaga taagcactca tagcagattc ttcattaata
     9061 atcctgcaat tttttcaaac caagattttc aaactgcttt ttcacatagt cattcacatc
     9121 cgactctaat ttccagttta ctaacatatt attttctttc attaaaacac tgtcgcttct
     9181 tctagcgtaa acttgacatt atcttcaatc catttacggc gtggttctac cttatctccc
     9241 atgagaacat tgacgcggcg ttcggcgcgc gctaaatctt caattgtgac acggatgagg
     9301 gtacgtgttt ctgggttcat ggttgtttcc cagagctggt ccgcattcat ctcaccaagt
     9361 cctttgtatc gttggagggt agcgccttta ccgaactgtt tacggagttc ttctagttct
     9421 ccgtccgtcc aagcgtaggc cacttcttct ttcttgcctt tacctttgga catcttgtaa
     9481 agaggtggga gggcaatata gacatgacct gcctcgacta gcggacgcat gtaacggtag
     9541 aaaaatgtca agagcaaggt ctggatatgg gcaccgtcgg tatccgcatc ggtcatgata
     9601 atgatcttat catagttggc atcttcaata gagaagtctg ctccaacacc cgcaccaatg
     9661 gtataaatca tggtattgat ctcttcattt ttgaggatat ccgccatctt ggccttggct
     9721 gtattgacaa ccttaccacg aagaggtaga atagcctgga acttgcggtc acgaccttgt
     9781 ttggcagaac caccggcaga gtccccctca actagataga gttcattctt agcaggattc
     9841 ttagattggg ctggggtcaa tttcccagac aacaagccct tatctttctt gtttttcttc
     9901 ccatttcggc tctcatcacg cgccttacgt gctgcttcac gagcatcacg ggccttgata
     9961 gccttgcgga tgaggttaga agctaattcc ccattttcca taaggaaaaa ggtcaactta
    10021 tcagccacta ttccatccac aactgggcga gctagggggc ttcctagttt atccttggtc
    10081 tgtccttcaa actgcaagtg ttcttcagga actaagatag aaagaacggc cgctagtccc
    10141 tcacgatagt ctgaaccttc aaggttttta tctttttcct tgagaagacc tgttttacgt
    10201 gcatagtcat tcatgacctt ggtaatggca gacttgagtc ctgtctcgtg cgttccaccg
    10261 tccttggtgc gaacgttatt gacaaaggat agaatgttat ctgagaatcc gtcattgtac
    10321 tggagggcta cttccacttg aaaaccattg tcttcccctt caaagtaaag aactggcgtc
    10381 aagatttcct tatcttcgtt gagataagaa acaaaatctt gtactccatt ctcatagtgg
    10441 aactcaatcg cttcatctgt tcgcttgtcc gttaaagaca aggtcacatt tttcaagaga
    10501 aaggctgatt cattaaggcg ctctgaaatg gtattgtact tgaaatctgt cgtagaaaag
    10561 atagtcgcgt caggcataaa agtaactttg gtgcctgttt tagacttggg tgctgtaccg
    10621 attttcttca aagtcgtgac aggttttcca ccattttcaa aacgttgctt gtaaactgcg
    10681 ccatcacggg taatttcaac ttctaaccag ctagaaaggg cgttaacaac ggaagaaccc
    10741 actccgtgaa gtccacctga tgtcttatag ccaccttgac cgaatttccc tccggcatga
    10801 agaatggtaa agataacctc aacagttgga attcccatag cgtgcatacc tgtcggcatc
    10861 ccacgtccat ggtcttgaac cgttagacta ccgtctttat tgatagttac atcaatacga
    10921 tcaccaaacc cagacaaggc ttcatcgact gcattatcaa cgatttccca aactaggtga
    10981 tgaagaccag cgccatcggt cgatccaata tacatccctg gacgttttcg gaccgcatcc
    11041 aacccttcta gcacctgaat agcatcatca ttataattgt taatattgat ttcctttttt
    11101 gacacaagga acctcctatt cgttcatctt tactattcta caggttttcc aaggattttg
    11161 caaaattttt ctttctccga tgtgacaatt tcagcagaga ttctctgctt ttctttccca
    11221 attcatgata taataggagt atgattacaa tagttttatt aatcctagcc tatctgctgg
    11281 gttcgattcc atctggtctc tggattggac aagtattctt tcaaatcaat ctacgcgagc
    11341 atggttctgg taacactgga acgaccaaca ccttccgcat tttaggtaag aaagctggta
    11401 tggcaacctt tgtgattgac tttttcaaag gaaccctagc aacgctgctt ccgattattt
    11461 ttcatctaca aggcgtttct cctctcatct ttggactttt ggctgttatc ggccatacct
    11521 tccctatatt tgcaggattt aaaggtggta aggctgtcgc aaccagtgct ggagtgattt
    11581 tcggatttgc gcctatcttc tgtctctacc ttgcgattat cttctttgga gctctctatc
    11641 ttggcagtat gatttcactg tctagtgtca cagcatcgat cgcggctgtt atcggggttc
    11701 tgctctttcc actttttggt tttatcctga gtaactatga ctctctcttc atcgctatta
    11761 tcttagcact tgctagtttg attatcattc gtcataagga caatatagct cgtatcaaaa
    11821 ataaaactga aaatttggtc ccttggggat tgaacctaac ccatcaagat cctaaaaaat
    11881 aaaacgccag ttctgtactg accccaaaaa gttagacaat taatttatcc gaaggattta
    11941 gttctgtatt gcacagggct aagtcctttt agttttacct taattcgttt attgttgtag
    12001 taatcaatat agtctacaat ggcttgttcc aattgcttaa gcgactgaaa cgacttctca
    12061 taaccgtaaa acatttccga tttcagaatc ccaaagaagg actccatcat accattgtct
    12121 gggctgttac ccttacgtga catggatgct tgaattccct taccctcaag aaactgatga
    12181 taagaatcgt gttgatattg ccagccttgg tcactatgga gaatcgta
//
LOCUS       DAVMCG010000049        11814 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVMCG010000049 DAVMCG010000000
VERSION     DAVMCG010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.050"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            116..769
                     /locus_tag="VYP66_001790"
     CDS             116..769
                     /locus_tag="VYP66_001790"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1851292.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            779..1243
                     /locus_tag="VYP66_001791"
     CDS             779..1243
                     /locus_tag="VYP66_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1851293.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPELDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1256..2524
                     /locus_tag="VYP66_001792"
     CDS             1256..2524
                     /locus_tag="VYP66_001792"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1851294.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2538..2798
                     /locus_tag="VYP66_001793"
     CDS             2538..2798
                     /locus_tag="VYP66_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851295.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2809..4170
                     /gene="pdrM"
                     /locus_tag="VYP66_001794"
     CDS             2809..4170
                     /gene="pdrM"
                     /locus_tag="VYP66_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1851296.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4324..5292
                     /locus_tag="VYP66_001795"
     CDS             4324..5292
                     /locus_tag="VYP66_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1851297.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5308..6300
                     /locus_tag="VYP66_001796"
     CDS             5308..6300
                     /locus_tag="VYP66_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1851298.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6518..7561
                     /locus_tag="VYP66_001797"
     CDS             6518..7561
                     /locus_tag="VYP66_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1851299.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     RVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGIQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7625..9310
                     /gene="lpdA"
                     /locus_tag="VYP66_001798"
     CDS             7625..9310
                     /gene="lpdA"
                     /locus_tag="VYP66_001798"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1851300.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9374..10363
                     /locus_tag="VYP66_001799"
     CDS             9374..10363
                     /locus_tag="VYP66_001799"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1851301.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VYP66_001800"
     CDS             complement(10430..11500)
                     /gene="xerS"
                     /locus_tag="VYP66_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1851302.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3515 a         2209 c         2650 g         3440 t
ORIGIN      
        1 tcacgtattc aaatcgtata tagtcgattt attaaatctt tagataaact gtaaaaagtg
       61 gtttccatag ccactttttg ctataataga ggcagtaaaa atgaaggagt cggctatgga
      121 acactcgtct tggcatgctt tgattaaggc gcaattacct gagggttatt tcgggaaaat
      181 caatcagttt atggagcagg tctattctca ggggattatt tatccaccca aggaaaaggt
      241 ttttcaggct ctcttgacaa cactgcttga agaagttaag gtggtaattc tagggcaaga
      301 cccctatcac ggaccaggtc aagcgcaggg cttgagtttt tccgtacctg actctatccc
      361 agctccacca tccttgcaaa atatcttgaa agaattgtca gatgatatcg gagttaagaa
      421 atctcatgat ttgacagctt gggctgagca aggagtcttg cttcttaatg cttgtttgac
      481 tgttcctgct ggacaggcca atggtcatgc tggtcaaatc tgggagcctt ttactgatgc
      541 tgtgattcag gtggtcaatc atctagatag accagtcgtt tttgtactct ggggagctta
      601 tgcacgtaag aagaaggcct tagttaccaa tcctcatcac ttgattattg aatcagccca
      661 tccaagtcct ttgtcggttt atagaggatt ttggggttcc aagccttttt ccaaggccaa
      721 tacattctta aaagagacag gacaagagcc aatcgattgg cttagataag gagaaaatat
      781 gcctcagtta gcgacgattt gttacattga taatgggaaa gaactgctca tgctccatcg
      841 taataagaaa cccaatgatg tccatgaagg gaaatggatt ggtgtgggtg gtaagctaga
      901 gagaggagag acgccccagg aatgcgcggt acgtgaaatc cttgaagaaa cagggctcaa
      961 agccaagcca gttctaaaag gtgtcatcac ttttcctgaa tttacaccag aattagactg
     1021 gtacacctat gtttttaagg tgacggagtt tgagggcgac ttgattgact gcaatgaggg
     1081 gatgctagaa tgggttccct atgatgaggt tttgagcaag ccgacttggg aaggtgacca
     1141 cacctttgtt gagtggcttt tagaggataa acccttcttt tcagccaagt ttgtttatga
     1201 tggggataaa ttgttggata cccaagttga tttctatgaa taaaggagaa agcagatgct
     1261 actaatcaaa aatggtcgtg taatggatcc caagtctggt ttggatcaag tttgtgatgt
     1321 cttagttcaa gatgggaaaa ttatcaaaat tgcgcctgag atcacggaag aaggagcaga
     1381 aacgattgat gctactggtc atgtggttgc tcctggtttg gtcgatattc atgtgcattt
     1441 ccgtgaacct ggtcaaacac ataaagaaga cattcatact ggtgccctag cagccgctgc
     1501 aggtggtttt actactgtcg tcatgatggc taataccagt ccaaccattt cagacgtgga
     1561 gactttgcaa gcagttctcc agtcagctgc caaagagaag attaatgtca agacagttgc
     1621 gaccattact aaaaacttta atggtaaaaa cttgactgac tttaaggcac ttttagaagc
     1681 tggtgcggtt ggtttctctg atgacggtat tccgcttgag agcagtaaga ttgtcaagga
     1741 agccatggag gaagccaaaa aactcaatac ctttatcagc cttcatgagg aagatccagg
     1801 tttgaacggt gttcttggct ttaatgaaaa tattgctaga gaacatttcc atatctgtgg
     1861 tgctactggg gtggctgagt acgctatgat ggcgcgtgat gtcatgattg cctatgcaac
     1921 taaagcccat gttcacatcc agcatttgtc taaggaagaa agtgttaaag tagtggagtt
     1981 tgctcagggg ttaggtgcag aagtcacagc agaagtagca ccacagcatt tctctaagac
     2041 agaagcactt cttttaacac aaggtagcaa tgctaagatg aatccaccgc ttcgtttgga
     2101 atcagaccgt cgtgccgtta tcgaaggtct caaatcaggt gtcatcacag ttattgcgac
     2161 tgaccacgcg cctcatcatg tagatgaaaa aaatgttgaa gatattacca aagtgccatc
     2221 tggtatgact ggcttagaaa catccctgtc tctcggcttg acctatttgg tagaagctgg
     2281 tgagttgagc ttgatggaat tacttgaaaa aatgacatac aacccagcca agctttacaa
     2341 ctttaaagca ggttacttgg ctgagaatgg tccagcagat atcactattt ttgatgccaa
     2401 ggctgaccgc cttgtggact cccattttgc ttccaaagca gctaattcac cattcatcgg
     2461 tgaaacctta aaagggcagg ttaaatatac catctgtaag ggacaaatcg tctatcaagc
     2521 ttgataggag ttagaatatg aattattttc gaaaacgtag ggagagacaa gcgaaatcta
     2581 atagtggaat ttactgtccc gcagctaatc gttccaaaat tcaatatgaa actaaagaaa
     2641 aagctgacca tgcggttcaa tatgataacg gaggtttagt tagaagctat tattgtcgta
     2701 catgtgcgtg ttggcatact acttcaaaat ctaataaacc tccgctaagt ttgaaaaact
     2761 atggtctgaa actctttggt ttagataaat cagaatagaa agagaagtat gtataagaca
     2821 aagtgtttac gagagaagtt agtattattt ttaaaaattt tcttcccaat cctgatctac
     2881 caatttgcca attattctgc ctcttttgtt gatactgcaa tgacaggtca atacaacact
     2941 atggacttgg ctggtgtatc tatggcaacc agtatctgga atcctttctt tacatttcta
     3001 acagggattg tgtcagcctt ggtgcctatc attggtcacc atcttggtcg aggcaaaaag
     3061 gaagaagttg cgtctgattt ttaccaattt atttatttgg ccttgggcct atctgtggtc
     3121 ttgctgggga tggtactttt cttggcacca acaatcttga atcatattgg gttagaagca
     3181 gcagtagcgg cagtagcggt tcgctatctt tggtttttat ctatcgggat tatccccttg
     3241 ttgctcttta gcgtcattcg ttccttgctg gattcgctgg gcttgaccaa actgtcaatg
     3301 tacctcatgc ttttgttact ccctctcaat agcggattta actatctctt gatttacggt
     3361 gcctttggtg ttccagaact gggaggggct ggtgctggtt taggaacatc cttggcctac
     3421 tgggtcttgc ttgggatttc tgttctggtt ttatttaaac aggagaagct caaagcctta
     3481 caccttgaga aacgaattcc acttaatatg gataacatta aggaaggagt tcgtttaggt
     3541 ctgcctattg ggggaactgt cttcgcggaa gtggctatct tttcagtggt tggcttgatt
     3601 atggctaagt tttcgtcctt gattatagct agtcaccagt cagctatgaa cttttcaagt
     3661 cttatgtacg cctttcctat gagtatctca tcggctatgg ctattgtcgt ttcctatgaa
     3721 gtgggagcca agcgatttga tgatgcgaaa acctatattg gtctaggaag atggactgct
     3781 ctcatttttg cggccttcac cctaaccttc ctttacattt ttaggggaaa tgtggccagt
     3841 ctttatggta acgacccaaa atttatcgat ttgacagcgc gttttttaac ttatagtctt
     3901 ttcttccagt tagcagatac ctttgcggca ccgcttcagg gaattttgcg ggggtataag
     3961 gatacagtta ttccttttta ccttggtttg cttggttatt ggggcgtagc aatccctgtg
     4021 gctacgctat ttgattccct aacagatttt ggagcttatt cttactggat cggcttgatt
     4081 attagtttga ttgtgagtgg ggcgctctac cgttggcgtt taactgtgat tatgaagaga
     4141 tttgaatctt tagcaaaatc caaacgctaa aaagtttgtg aaaaaatatc cttgacaaga
     4201 aaatcccttg ttttcacggg gttttctttt ttattttgtg aaatttcttt tagaaaaact
     4261 ttgacagtat ttgccaaaaa cggtaaaata gtaaggtaag aagaaagtta gaaaggcaag
     4321 aagatgtcaa ctttagataa aaatcttttg ctagaaatgt tccgtaagat ggaagaaatc
     4381 cgtcgcatgg acttaaaaat tgcacaatta gtaaagaaag ggaaagtgcc aggaatgacg
     4441 cacttttctg ttggtgaaga ggcagctaac gtgggggcta tgttagctct caatccagat
     4501 gatctgatta cctcaaacca ccgtggacac gggcaagcta ttgctaaagg gattgacctc
     4561 aacggaatga tggctgaaat ccttggtaaa tacactggaa cctgtaaagg gaaaggtgga
     4621 tctatgcata tcgctgacct tgatgctggg aaccttggtg ccaatggtat cgtaggtggt
     4681 ggtatgggga tcgctgtcgg tgcagccctc agtcagcaaa tgcaaaatac cggtaaaatc
     4741 gttgtttgct tctttggaga tggtgcgacc aatgaaggtg ttttccacga agcagtgaac
     4801 atggcttcta tctggaacct gccagtcatt ttctattgca ttaacaacgg ttacggtatc
     4861 tctgcggata tcaagaaaat gaccaatata gaacatatcc atcaacgtag cgccgcttat
     4921 ggaattcctg gaatgttcat cgaagacggt aacaatgtca tcgatgtcta tgaaggattt
     4981 cagaaagctg tagaccatgt tcgcagtggc aatggtccag tcttgattga aagtgtaact
     5041 tatcgctggc tcggtcactc atcatctgac cctggtaaat atcgtacgcg tgaagaagtg
     5101 gaattgtgga aacaaaaaga tccaatcgaa aacctccgca attaccttat tgaaaataac
     5161 attgcaagtg ccgaagaatt ggaagaaatc caagcgcaag taaaggaagc agtagaagct
     5221 tctgttaaat ttgcagagga aagcccattc ccaccgcttg aatcagcctt tgaagatatt
     5281 tacgcagact aaggagaaag agataaaatg gaaacaaaaa caatgtcctt ccgtgacacc
     5341 attatccttg ctatgtctga ggaaatgcgt cgcgatgaaa atgtgttctt gatgggagaa
     5401 gacgtcggtg tcttcggagg agacttcggt acttctgttg gaatgcttga agaatttggt
     5461 ccagaacgcg tccgtgactg tccgatttct gaagctgcca tctctggagc agcagcagga
     5521 gcagccatga caggacttcg tccaatcgtc gatatgacct tcatggactt ctctgttatt
     5581 gccatggaca atatcgtcaa ccaagctgct aaaacacgtt acatgtttgg tggtaaaggt
     5641 caggttccaa tgactgttcg ttgtgcagct ggtaacggag ttggctctgc cgcccagcac
     5701 tcacaatctc tagagtcttg gtttactcac attccaggac ttaaggttgt ggcacctgga
     5761 acacctgcgg acatgaaagg cctgcttaag tcttctatcc gtgataaaaa cccagttatt
     5821 atacttgagt acaagtcaga atttaaccaa aaaggggaag tgccagttga tccagactac
     5881 acaattccac ttggggttgg tgaaatcaaa cgccaaggaa cggatgtaac agttgttact
     5941 tatggaaaaa tgcttcgccg tgtggttcaa gctgctgaag aattagcaga agaaggaatt
     6001 tcagttgaaa ttgttgaccc acgtaccctt gttccgcttg ataaggatat catcataaac
     6061 tcagtgaaga agactggtaa ggttgttctg gtcaacgatg cccacaaaac aagtggctat
     6121 atcggtgaaa tttcagctat tatttcagaa tcagaagcat ttgactatct agatgcacca
     6181 atccgccgtt gtgcaggaga agatgtgccg atgccttatg cacaaaacct agaaaatgca
     6241 atgattccaa cagttgaaag tatcaaagat gcaatccgaa aaacttataa caaagaatag
     6301 agttacataa gataagttat gtaaataaaa taaagctgac gagaaacttt gtatctttta
     6361 ggtgcagagc tcttcgtcat taatatctta gattagagca cgggctaaaa gctcggaaaa
     6421 aagataaatc tccttggctt catcgaagcc atcgtcgatt tcctattttt cagtcgcttt
     6481 tgacgccctt tgtatcataa atagaattgg agaggtcatg gctgatgaca agctaagagc
     6541 gactcctgca gctagaaagt tagcggatga tttagggata aacctctacg acgtttctgg
     6601 ctcaggtgca aacggtcgtg tccacaaaga agacgtggaa acttataaag acacaaacgt
     6661 ggttcgcatt tcgccacttg caaaacgaat tgccctcgaa cataacattg cttggcagga
     6721 aatccaagga accggtcatc gtggtaaaat catgaagaag gatgttttgg ccctgcttcc
     6781 tgaaaatatc gaaaacgata gcatcaaatc tcctgctcag attgaaaaag tggaagaagt
     6841 tcctgataac gtaacaccat atggtgaaat cgagcgtatt ccaatgacac caatgcgtaa
     6901 ggttattgcc caacgcatgg ttgaatctta cttgactgcg ccaaccttca ccctcaacta
     6961 tgaagttgat atgactgaaa tgttggctct tcgtaagagg gttcttgagc caatcatgga
     7021 agcaactggg aagaagacta ctgtaacaga ccttctttca cttgcagttg ttaagactct
     7081 tatgaaacat ccatacatca acgcttcatt gacagaagat ggcaagacta ttatcactca
     7141 caactatgtc aatcttgcta tggcagttgg gatggataat ggattgatga cacctgttgt
     7201 ttacaatgct gagaagatga gtctttcaga actggttgta gcctttaagg atgttattgg
     7261 ccgtaccttg gatggtaaat tggctccaag tgagttacaa aattcaacat tcacaatcag
     7321 taatttggga atgtttggta ttcagtcctt tggtccgatt attaaccaac ccaactcagc
     7381 tatccttggt gtcagttcga caatcgagaa gccagttgtc gtcaatggtg aaattgtgat
     7441 tcgcccaatc atgagtttag gattaaccat tgaccaccgt gtcgtagatg gtatggctgg
     7501 tgctaagttt atgaaggact tgaaagagtt gattgaaacc ccaatctcaa tgttgattta
     7561 agagcaagag tattcatttt taagatatag ataaaggaag gaagacatgg ccttagaaat
     7621 aattatgcca aaagccggcg tggatatgac agaaggacaa atcgtccaat ggaataaaaa
     7681 agtcggagaa tttgtaaaag aaggagaaat ccttttggaa atcatgactg ataaagtcag
     7741 catggaattg gaagccgaag aagatgggta cttgattgcc attctcaaag gagatggtga
     7801 aactgtccct gtaacggaag ttatcggtta ccttggtgaa gaaagggaaa acatcccaac
     7861 agctggagca gcatcgccag aagctagccc tgtacctgta gcaagtacct caaacgatga
     7921 tggtaagagc gatgatgctt ttgatatcgt tgtgattggt ggaggtcctg ctggttatgt
     7981 tgcagccatt aaagctgccc aactcggcgg taaggttgcc cttgttgaga aatctgaact
     8041 tggtggaacc tgcttaaacc gtggatgtat tccaaccaag acctaccttc ataacgctga
     8101 aattattgaa aatatcggtc atgctgcaaa tcgtggtatc gtgattgaaa atcctaactt
     8161 cactgttgat atggaaaaac ttttagaaac taaatctaaa gttgttaata ctcttgttgg
     8221 tggtgttgca ggacttcttc gtagctacgg agttactgtt cataaaggaa ttggtacaat
     8281 cactaaagac aagaacgtct tggtaaatgg ctctgaattg cttgaaacca agaaaatcat
     8341 tcttgctggt ggttcaaaag tcagcaagat caatgtccct ggtatggaat ctccacttgt
     8401 catgactagt gatgacattc ttgaaatgaa cgaagtgcca gaaagccttg ttatcatcgg
     8461 tggtggagtt gtcggtatcg aactcggtca ggccttcatg acatttggtt caaaagtgac
     8521 tgttatcgaa atgatggacc gtatagttcc agctatggat gcggaagttt ctaagaacct
     8581 tcgcttgatc cttgagcgta aaggaatgac catcttgact ggtactaaac tgcaagaaat
     8641 cattgaggaa aatggtcaac ttcgtatcaa ggttgaagga aaagacgata tcatcgcaag
     8701 caaagctctt ctttcaattg gtcgtatgcc agaccttgaa ggtattggag aggttgagtt
     8761 tgaattggat cgtggttgta tcaaggtcaa tgaatacatg gaaacttcag ttccaggcat
     8821 ttatgcacca ggtgacatca acggtactaa gatgttggct cacgcagctt tccgcatggg
     8881 tgaagtttcc gctgaaaatg cccttaaagg aaatcatgca gttgccaaat tgaatttgac
     8941 tcctgcagcc atctacactc tccctgaagt agcagcagta ggtttgacag aagaacaagc
     9001 ccgtgagaaa tacgatgttg ccatcggtaa gtttaacttt gctgctaacg gtcgtgctat
     9061 tgcatctgac gcagctcaag gtttcgtaaa agttatcgct gataagaaat acggagaaat
     9121 ccttggtgta cacattattg gtcctgcagc cgcagaatta ataaacgaag catcaagcat
     9181 catcgaaatg gaaatcactg ttgaggaaat gctgaagacc atccacgggc acccaactta
     9241 ctctgaagtg atgtacgaag cgtttgcaga tgttctagga atggccatcc attcacctaa
     9301 gaaaaaataa aacgaagata gattagactg gaaggttatt tccagtctct atcatataaa
     9361 gtaaagggat atcatgaaat acattatcaa tcattcaaat gacactgctt ttaatattgc
     9421 cttggaagaa tacgccttta aacacctttt ggatgaggat caaatcttcc tactttggat
     9481 taacaagcca tctatcattg ttggtcgtca ccagaacact atcgaagaaa tcaaccgtga
     9541 ttatgttcgc gaaaatggta ttgaggtagt tcgccgtatt agtggtggtg gagctgttta
     9601 ccacgattta aataacctca actacacgat catctccaaa gaagatgaaa ataaggcatt
     9661 tgacttcaag agcttctcaa ctccggttat caataccctg gctcaacttg gggttaaagc
     9721 tgagttcaca ggtcgtaatg accttgagat tgatggtaag aagttctgtg gcaatgccca
     9781 agcctatatc aacggccgta tcatgcacca cggttgcttg ctctttgacg ttgatttgtc
     9841 agtcctcgca aatgccctta aggtttcaaa agataaattt gaatcaaaag gtgtgaaatc
     9901 cgtccgtgcc cgtgtaacca atattatcaa tgaattacca aaaaaaatca cagtcgaaaa
     9961 attccgtgat ttactcctgg aatacatgaa aaaagagtac ccagagatga ctgaatacgt
    10021 cttttcagaa gaagaattgg ccgaaatcaa tcacatcaag gatactaagt ttggaacttg
    10081 ggactggaac tatggtaaat cacctgaatt taacgtccgt cgtggaacca aattcactag
    10141 tggtaaggtt gaagtctttg ctaacgttac tgaatcaaaa atccaagaca tcaagattta
    10201 tggtgacttc tttggtattg aagacgttgc tgcagtagaa gatgtccttc gtggggtgaa
    10261 atacgaacgc gaagatgttc ttaaggcgct aaaaaccatt gatatcacac gctacttcgc
    10321 tggtattagc cgtgaagaaa tcgctgaagc ggtagttgga taaatcaaaa aaagaagttg
    10381 gccaacttct ttttttgata tttatttaca taatttaaaa tacgtaaaat cataaactat
    10441 ctagagcatt cttttgttca tcattaacaa tatgggtata gaggtcagtg acttgtgtgc
    10501 tggcatgtcc tagttggtga ctgactaaaa cttgtgattt agtcgcatca tagagcctag
    10561 ttgctagcgt atggcgcagt ttatggggtg ttacacgcac tttaaaatcc tctgagtatt
    10621 tagcaaccat tttctcaacg ctagaagcat cgatacgatt aggaacacct ctgtagagag
    10681 ttaaaaaaag ggctgtatct gttttttccg ttttatagcg ttgattccga atggccagat
    10741 aattctctaa ataaggttta gcaaaagcag cgacattgac tgagtcacgt ttgccacctt
    10801 ttcgagtaac atcaataacc atcattttta gattgagatc tcttagatct agattaacag
    10861 cttcagataa gcgaacacca gatgccaaga gaagggcaat aatggctaaa tctcgttctt
    10921 tatttttgtt gaatgatgag agagctcgat ttgaaagctg ttgtgggtgc tcttgatcga
    10981 tataagttag aaaaccttct gtttcatcac ctagaaagag tttttgcttg atattttcag
    11041 ctctggcagc aagggtttct ttctttttct tggttgaaac ttttttcatt acattacgat
    11101 agaaataagg ttccccctga tcgttttcaa cctcctcggt tagatacttg taaagactag
    11161 aaagtgctga taaggttcga ttgatagttg tctgtgaaac accttgtttt gttgtattag
    11221 cattcagcaa gggacgttca cgtagataaa ggataaagga ttccatgtct ttcttagaca
    11281 tattttccaa aactgataaa ggaatatcgg atattttatc agcgtttgaa ataccagact
    11341 ccaaaaccca gctgaaaaat cggtcatatt ccttaaggta ttcgtacagg gttgtaaaac
    11401 tgtagggcac agccagctta gattggtagt attccagaac ataccagggc atgagttgtt
    11461 ttagtttgtc gattcgttcc agtaaaatct cacgtttcat gtattttctc cataagtaag
    11521 tatactagta gtatagcata gacttgtata tttttcaaga aaattatagt ttttctgaaa
    11581 gatgttatag gagtttttca aagtgataaa aagacttaga cctacaaaca aaacagaata
    11641 aggaaaataa taaaaatctc acccactaaa cttctgttaa tactacataa ctgaagagct
    11701 atataaggag ctatgagata caaaacacat tgtataatag attgaaacta gaatagtaca
    11761 tctgaacttc taaaacattg ctagaaattg atttgattgt cctgattgtt ttat
//
LOCUS       DAVMCG010000050        11737 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVMCG010000050 DAVMCG010000000
VERSION     DAVMCG010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.051"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..338
                     /locus_tag="VYP66_001801"
     CDS             <1..338
                     /locus_tag="VYP66_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nickase"
                     /protein_id="HEV1851303.1"
                     /translation="SGKLKKLLSDKEKLSPKKWNEEKILLMSNLEEINKEKDKIKDEY
                     QEINHIKYSVDFVNKELGIDLSIEIDKLIKQGEKPSVIAQIKKFQDQVNKDNEYREMM
                     KNKKMDQER"
     gene            412..585
                     /locus_tag="VYP66_001802"
     CDS             412..585
                     /locus_tag="VYP66_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851304.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            771..1298
                     /locus_tag="VYP66_001803"
     CDS             771..1298
                     /locus_tag="VYP66_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEV1851305.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            1425..2153
                     /locus_tag="VYP66_001804"
     CDS             1425..2153
                     /locus_tag="VYP66_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1851306.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRIKRLRRISGGDTYTIIYLKLLLL
                     SLKDEGKLYYDGVESDFIKELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTE
                     IPNLIGSETAWAEKKRRYRQNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKS
                     TPIFYGEFKNVRLSKEEYKNLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWY
                     EEDKDKLRQKGLNKKMNYDVGESL"
     gene            2837..2998
                     /locus_tag="VYP66_001805"
     CDS             2837..2998
                     /locus_tag="VYP66_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851307.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            3090..4769
                     /locus_tag="VYP66_001806"
     CDS             3090..4769
                     /locus_tag="VYP66_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1851308.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSRIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            5037..5603
                     /locus_tag="VYP66_001807"
     CDS             5037..5603
                     /locus_tag="VYP66_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851309.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            5924..6112
                     /locus_tag="VYP66_001808"
     CDS             5924..6112
                     /locus_tag="VYP66_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1851310.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            6174..6932
                     /locus_tag="VYP66_001809"
     CDS             6174..6932
                     /locus_tag="VYP66_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1851311.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            6990..7844
                     /locus_tag="VYP66_001810"
     CDS             6990..7844
                     /locus_tag="VYP66_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1851312.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            7956..8840
                     /locus_tag="VYP66_001811"
     CDS             7956..8840
                     /locus_tag="VYP66_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1851313.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            9003..10130
                     /locus_tag="VYP66_001812"
     CDS             9003..10130
                     /locus_tag="VYP66_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEV1851314.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLFEIIKNIKNLVINLN"
     gene            10079..11415
                     /locus_tag="VYP66_001813"
                     /pseudo
     CDS             10079..11415
                     /locus_tag="VYP66_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(11456..>11737)
                     /locus_tag="VYP66_001814"
     CDS             complement(11456..>11737)
                     /locus_tag="VYP66_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV1851315.1"
                     /translation="TQLAINCFILSIDKEEFSNCSYLINEIKGLLENELNFYEQTVFL
                     YATGYYEFKRQLSSGIETMKQAIQVLDILGEDKLKLHYTSHFDKLVNNK"
BASE COUNT         4539 a         1602 c         2304 g         3292 t
ORIGIN      
        1 taagtgggaa attaaaaaaa ctcctatcag ataaggaaaa actaagtcct aaaaagtgga
       61 atgaagaaaa aattctttta atgtcaaatc ttgaagaaat aaataaagaa aaagacaaga
      121 taaaagatga ataccaggaa attaatcata taaaatattc agtagatttt gtaaacaaag
      181 aacttggtat agatttatcc atagaaatag ataagctaat aaaacaggga gaaaaaccaa
      241 gtgtaatagc acagattaaa aagttccaag accaagtcaa taaagataat gaatacagag
      301 aaatgatgaa aaacaagaaa atggatcaag aaagataaga cctggtaaaa atatcttatc
      361 caagctataa tatgaccaaa caactaaagt cagatctagg aggtaataga gatgaataaa
      421 aggcaagagc taatagatga actcataaaa gcaaatgaag atggaacata caaaacctat
      481 aaaagcacag aagaaataaa agcaatgaac aatgaagaaa tacagattat atattctaac
      541 atgaaaaact atctatcaga caaaagaaca cacataaact attaaaggtg gaaaggtagt
      601 gtaagctatt tttaaaagta taaaaggtac aaagacctaa gaaatatata aaaacatcaa
      661 aataaagtat tccaccacca agaacaataa aataaaaaca agcaaaggga agtatagaaa
      721 aattaaaacc tatacttccc ttttttaatt caaacaaagg agagaaaagc atgataaacg
      781 aagaaataag caaggaagca ggtcaagcag cacaaaccat aatatcatac acaataaagg
      841 caacaaaaga atcaatcaat ttagaaaaag aaataagaaa aaagatgaat gaaactttag
      901 aaaaagcaaa tggaaactta aaaagtctta tgggcgatga aatgaaaata aaagacctct
      961 acaagaaagg acaactagaa aatataagca tagatcaaat cgacctcaaa gacttaaaaa
     1021 aagaactaaa caaacttgga gtaagtttct cagtaatgaa aaacaaagaa agcaaaaact
     1081 atgaaatatt cttccaagcc aaagacataa aagtaatgga atatgccttt aagcaagtca
     1141 tagccaagga aaataaaaaa gaaaaagaaa gtatcctaaa acaaataaag aaatacaaag
     1201 acctatccaa aaacaaagat aagacaaaag aaaaaggaaa aaggaaagta aaagaaaaag
     1261 taaaaccaaa caaaaaagat atgaccagag aaatctaaag ggagtaacga aaagttacac
     1321 ccttaaataa ccataataac aagacttccg aaaaacagaa gtccagaatt ccgaaaatcg
     1381 gaaatcaaga atttcgatta tcgaaaatca agaaaggagc agatatggca acaaacaaaa
     1441 gatactattg gataaaatta aaagaagaat ttttcacaga caaaaggata aaaaggttaa
     1501 ggagaatatc tggaggagat acctatacga taatctacct aaaacttcta ctactaagcc
     1561 taaaagatga gggcaaactc tattatgacg gagtagaaag tgattttata aaagagttag
     1621 cactaaccat agatgaaaca gacgatgatg taatggtaac agtaaattat ttaatcaatc
     1681 aaggcttatt agaagttgta acagaaaatg atgaatacta cctaactgaa ataccaaact
     1741 taatcggatc agaaacagcc tgggcagaga aaaaaagaag atacagacaa aataaacaga
     1801 ggacattgtc cttaatgagt ccaacccatg tccgacaaga gatagagata gagaaagata
     1861 tagagataga taaagagaga gagggagaga tagataaaaa gtccaccccc attttttatg
     1921 gagaattcaa aaatgtaagg ttaagcaaag aagaatataa aaatctaaaa gaaaaattaa
     1981 actcacacac agatataatg ataaataaac tatccagata catggaaagc agtggtaaga
     2041 cctatcaaaa ccactatgtg acaatcttaa aatggtatga agaagataaa gacaaactaa
     2101 gacagaaagg tttaaataaa aaaatgaatt atgatgtagg agaatcttta tagataaaaa
     2161 gaggtggaaa ggcactatta aagactttaa gtttaaaaag gtatcaaagt atgccagaga
     2221 taaaaaaata taaatatgac actttaaagg cgattagaaa attaaagaaa tgctagaaga
     2281 cttttagatg acagttacca agagggtcta attttcactg ctacttatgc agtaggaatt
     2341 ggaccttttt atataagcaa attctatttc aaaattggtt accaagaaag acttcttttc
     2401 actgttaagt ataagagggt aatttataga attttgttac atcaagataa atattttctg
     2461 atggtcaaat tttaaaaaga ttaataactc tcgataaatt ttgaacctta acaattgaat
     2521 agaccaagac aagacgttaa ttatttttgg agcgtaataa cctatccgtc aagatctttc
     2581 ggctgaataa ttcggcaaaa aaagttctgc taagcaaaaa gaaagtgagc gataagtaag
     2641 agtttgaata tagggaggga taccctatcc gctatgaaga aaatgaggat aatgatactt
     2701 ctaaggttga agcaggctca tccggaatag aggcggaggt gagattccta tgttgctaat
     2761 ccaaagcact tgtcaatgtc aaaaaactta attaaacaaa taattattag atataaaact
     2821 ttagaggagg tatatattgg acaatgactg gaatggattg gctgatttaa tagcaaatct
     2881 gattgcaaaa tatgctggtg ctttagattt agataatcta cccgatccaa cgccagcaaa
     2941 aaatcaagag atgaaaaata gttttgacat ggcaaaaaca caaattgaga cggactaata
     3001 aaagtgttat aatatacttg aaatgatagt ccaaacttaa attaaaaaaa ttatatatga
     3061 tatagaaaaa ttatattgag gttaatacta tgtcaaaaga aaaaataaaa gtatacctct
     3121 atacacgagt atctacgtca atacagatag aggggtattc gttagaggca caaaaatcac
     3181 gaatgaaagc ttttgctatt tacaatgatt atgaaattgt tggagaatat gaagatgccg
     3241 ggaagtctgg caagtctatt gaaggtagaa tacagttcaa tcgaatgatg gaagatataa
     3301 aatctggaaa agatggagta tcttttgttc ttgtgtttaa gttatcaaga tttgcaagaa
     3361 atgccgctga tgttctttct acacttcaga taatgcagga ttatggagtt aatcttatct
     3421 gcgttgaaga tggcattgat tcatctaaag atgctgggaa actaatgatt tctgttttat
     3481 cagctgtggc tgaaatagaa agagaaaaca tccgtattca aacaatggaa ggtcgcattc
     3541 aaaaagcaag ggaaggaaaa tggaatggtg gctttgctcc gtatggatat aaacttgaag
     3601 acggcaagct gtttataaat gaggaagagg cagttgcaat aagaacgatt ttcgaccagt
     3661 atgtaaatac tacgatagga gccaatggga tatctaaata cttagagaat catggaatta
     3721 gaaaaatccc aagacagaat ggtaagaatc ctttgtttga tgcaggtctt ataagaaaga
     3781 tattaaagaa tcctgtatat aatgggaaaa tagcatttgg aagaagaact ttagaaaaag
     3841 ttcatggtac aagaaatgaa tataagcagg ttgaacaaga tgaatatcta atatctgaag
     3901 ggatacatga agctatagtt tccgatgaag tttggcaagc tgctcaggtt aagctaaaat
     3961 ctcaagcaaa gaaatatgag catgtgaata aaggaaaaga tacacgcaca cacttgcttt
     4021 ctagaattgt aaaatgcccg atatgtggag tgggaatgtt tgggaacaag tgtatcaaga
     4081 aaaagaaaga tggcacaaag tataaagatt tttattacta tggttataaa cataggcaga
     4141 tgataagagg tcataagtgt acattcagta agcaaattag agaagaattg ttagatgatg
     4201 ctgttgcaga ggtgattgtc aagatagtaa gtaatccgaa atttgcttct atgatgcaag
     4261 aaaaaatcaa catgaaggtg gatacctctg aaatagaaaa agaaatagat aattaccaaa
     4321 aggaattgag aaagagtcat tctacaaagt ttaagctaat tgaggaaata gataatttag
     4381 atgttgaaga taagcattat aagagaagga aacaggattt agatgataga ctatatcgta
     4441 tgtatgacaa aatagatgaa ttagaatcat cactaattga tgcgaaagca aagaaacaga
     4501 ctattgaagc tgaaaagctt acaggagata acatatataa ggttctgatc tattttgata
     4561 agctctataa agtcatgaat gatgtagagc gtaggcagtt aatttcagct ttgatttctg
     4621 aaattcaagt ttatgaagaa aaacaatcta acggacaatg gctaaaatcc attactttta
     4681 agctaccaat tatagaagaa aatctcaaca taggtttgga taatgatgaa caagttgaat
     4741 gtgtaagttt attagagaaa cgtagttaat cctcaaaagg ttccccaaac cttttgagtc
     4801 ccactgacgc atcacgctga ggcggtatca ctgcttgtac gagttgaagc atcagcgaag
     4861 taaaagtaga tgttcagcca atgcgacgag gtgagaccga aggtcgataa ggtgtgttct
     4921 gggtatagga ctcgtaaagt aagtaggaaa tatgatgaga tgatacagag agcctgaatt
     4981 ggtcaggtga cgtgcttatt tacattagcc tgataatgaa aatggagaga ttatcgatgg
     5041 ttatattgga attgtaccaa aatgattatt ctaaagattt agtagcattt gattccatag
     5101 aagatgggaa agcctttgta gctcaaatcc cgggatacac tctggaaaca gaagatggtt
     5161 ttgaagtgga gtattttaat cctaaaaaca taccggatta tatggaaatt atttttaacg
     5221 gaaatattgt tcctttatct aaatttatgt tcgatcctga ggaaaatgta aacattattt
     5281 ggaaagagat ttcaaattta tccctcaaaa atgatagagt gatcgaagga tattcaaaaa
     5341 ttgatgcata tgtcgttaac aaccatgaag ttaaagccta tgtcgaaaca agagaaacga
     5401 actatcgtaa agcaaaagac ttcttagaaa gccgcggata tgaaatcgac agaagctttt
     5461 tcggaagtga agacggtgaa gcgattcttt acagaaaaaa agggatcgaa gtttggcatt
     5521 tcttgtgtca cttagaccca atgtttgtag agattgaaga tgtagaagga tatgttaaag
     5581 aagaagttgg agagattcaa tagtcaacca aagttccttg tgagtatata cctttgctag
     5641 taaaagagtc aaaacgttat aacgaagggg ggaagaaaac ccttgagtgt aagtcttttt
     5701 cttgtttaga gggaaagtat tagagtagcc gctcataatt tatactagat ttgataactg
     5761 atttgagaca gattttattt ctataaatat tgtgaaaatt ttttaatacc aaagatttaa
     5821 agttactgtg ttaaaaatcc tctccacttt taaactaatg tattataaaa gccagttgac
     5881 acaagtgtta cacctatgat agaattaact tgaggtgatg aaaatggcaa ccgataaaaa
     5941 tagaataatg attagcttgg atgataaaaa tctagagaaa cttgaaaatt tagtagaaga
     6001 tgctagagat agaaggggaa tgcgactaac aaagtcccag gttattgaat tactcctaaa
     6061 taccgttgat tatttcgatg atattatggg ggctatttac tcaaaaaaat aagagcaaaa
     6121 ttgctattat tttttacaaa ttggtgtaac actagtgata taggagtgat gaaatggttg
     6181 tttatattag acaaagtaaa ttaccaagtg aggtttcaat taataaatac aatgctcaag
     6241 taggtgccta cttacaagga gaagaagtta ttttatatca atctttttct gaaataaaag
     6301 agttaacaag tgaagatata gttgtagatt atataatgga gactagagca ttactaaaaa
     6361 tgatgggctt aaacgttccg gttcatgact atcctattga gcttaaagag ttttatggtc
     6421 gaaagattta tgctggtatt ttaggagaga ttgtgaatat acctgataat tggggaaaat
     6481 ttattaagcc taaagctggt tcaaaagtct ttactggaag agttgttaat ggaacccatg
     6541 atttaatagg tattggtcta cctttcgact atcctatatg gattagtgag gttgtagaat
     6601 tcatagctga atggcgttgt tttgtgttag atggtcgcgt attagatgtt cgaccctata
     6661 caggtgatta tcatgcacaa tttgatgcaa gtgtaattga tgaagcgata tcatgttgga
     6721 aagatgcgcc aatagcttat ggactagata tcggtgttac tcgcgatggc agaacacttg
     6781 ttgttgaagt aaatgatggt tatgcattgg gaaattatgg cctatctcct ttaaaatcaa
     6841 tcaattttca tagagctagg tggaaagaaa tggtaaaacc ctattttgaa aaaaatgaaa
     6901 tttttaaaat ccaacaggat gttattttct aaaataaata tggtagataa ccaatataaa
     6961 aagcatcaaa atgaacaagg aggaatctga tgcttggagc aattattgga gatattgtcg
     7021 gttctgttta cgaatggaac aatatcaaaa caaaggactt tcctttattt cggaaggact
     7081 gcttttttac agatgacacg gttatgacct gtgctgttgc agaagcaatt atgaatggtg
     7141 gacaaaaaga cgacttcatt gacgcgatga agaaatatgg cagaatgtat ccgaatgctg
     7201 attacggtgc tcggtttaat gcatggctaa acagcgataa ccgtgagcct tataatagct
     7261 ttgggaatgg atcagctatg cgtatttctc catgtgcttg gatcatggac tgtggttttt
     7321 atgcgaaaac tggtatatgg ccatcatcta gaggacttac gagtctttct gcagaggtaa
     7381 ctcataatca tccagaaggt gtcaaaggcg ctatggctac agctgatgct atctttctat
     7441 gtcgttttta ctttggtggt tattgtagag agtacgagca atcaattaac gacaatccta
     7501 cagagtgtaa aagacgaatt aaggattata tagaaaaaga atacgattac aatctatctc
     7561 aaactttaga tgaaatccgt cctaactatc gttttaacga aacatgtcag gaaactgtcc
     7621 ctcaagccat tatcgccttt cttgaaagta gagacttcga agatgcgata agaaatgcca
     7681 tctcacttgg tggcgacagt gatactctcg cagcaatcac ttgtagcata gcagaggcag
     7741 cttacggtat tcctgattgg atcaaggata aggcctattc ttacttggat gaacccttaa
     7801 aggatgtagt taggcgatgg gaaaatagaa taaaagcgta ttaatctcca gtacgtcaga
     7861 tttctctttt ctgtattttc attgtataat aggattacat ttacttgcat acgacgaaat
     7921 gtaaacattt ctgtttaaaa ttaaggataa aatcaatgaa aaaagcaatg gtaattatca
     7981 accctacttc tggtggcgag aaggctttgg attacaaaga aaagctggag aataaagcaa
     8041 aagaatactt tgaatatgtt gaaaccaaaa ttaccgaaaa agcgctggat gcaacacatt
     8101 ttgctgaaga agcttctcgt gagcagtatg atgcagtggt tgtgtttggt ggagatggaa
     8161 ctgtcaatga agtcatttca ggtattgatg agagagacta cattcctaag ttagggatta
     8221 tcccaggcgg tacgggtaac ctcattacaa aacttttgga aatcaatcaa gacatcgatg
     8281 gcgcaattga cgaactggat tttgatttaa ccaataagat tgatatcggt aaagcaaatg
     8341 acaactattt tggttatatc tttagtatcg gttctctgcc tgaggcgatt cacaatgttg
     8401 aaatagagga caaaacaaaa ttcggtattt taacctatgc tgtaaatacc atgaagtctg
     8461 tcatgacaga tcaggtcttt aacattaagg ttgagacaga aaatggaaat tatgttggtg
     8521 aagctagcca tgttttggtc cttttgacaa attacttcgc tgataagaaa atctttgaag
     8581 aaaacaagga cggctatgcc aacattttga ttctgaaaga tgcctctata ttctccaaat
     8641 tatccgtcat tcctgattta ttaaaagggg atgttgtcgc aaatgataat atcgagtata
     8701 tcaaagcgcg taatattaaa atctcttcag atagtgaatt ggagtcagat gttgacggag
     8761 ataaatcaga taacctacct gtagaaatca aagtcctagc tcagcgagta gaagtatttt
     8821 caaaaccgaa agaggattag tatatagaga aagccttttt taaggctttt tgtatacttt
     8881 aaaagatagt tcctttaaca acggacattc cttgcaaata gtttacaaaa atagtatact
     8941 ggatttattg agtttgaaaa cgtttgcgta aaatttgaat gaatacttta ggagacaaat
     9001 tgatggaatt gagtgctatt taccataggc ctgagtcgga gtatgcctat ctttataagg
     9061 ataagaaact ccatattcga attcgaacta agaaagggga cattgaaagc atcaacttgc
     9121 actatgggga cccttttatc tttatggagg agttttatca ggatacaaaa gaaatggtca
     9181 agataacttc tggtacctta tttgaccatt ggcaggttga agtgtcagtt gactttgcac
     9241 gtatccagta tctctttgag ctcagagata cagaaggtca aaatattttg tatggcgata
     9301 aagggtgtgt ggaaaattct ctagaaaatc ttcatgcaat tgggaatgga tttaagttgc
     9361 cttatcttca tgagattgat gcctgcaagg ttcctgactg ggtttcaaat acggtatggt
     9421 atcagatatt tcctgaaaga tttgccaatg gcaatgctct attaaaccca gaagggactt
     9481 tagactggga ttcatctgtc acacctaaga gcgatgattt ctttggtggt gatttacagg
     9541 ggattattga tcatatggat tacttgcaag acttgggtat tactggacta tatctttgtc
     9601 ccatctttga atctacaagc aatcacaagt acaatacgac agattacttt gaaattgacc
     9661 gtcattttgg agacaaggag acctttcggg aactggtgga tcaagcgcat catcgtggca
     9721 tgaaagtcat gctggatgcg gtatttaatc atattggttc gcaatctctt caatggaaaa
     9781 atgtcgtcaa aaatggtgaa cagtctgctt ataaggattg gttccatatt caacaattcc
     9841 cagtgacaac tgaaaagcta gttaataaga gagacttacc ctatcatgtt tttggtttcg
     9901 aggactatat gcctaagcta aatacagcca atccagaggt caagaattat cttttaaagg
     9961 ttgcgactta ttggattgaa gagtttaata tcgatgcttg gcgtttggat gtggctaatg
    10021 agattgacca tcagttctgg aaggattttc gtaaggcagt tttagctaaa aatcctgatc
    10081 ttttcgagat tataaaaaat ataaagaatc tagtcataaa tttgaattga aacaacgtct
    10141 ttattttttg cttcagcaat ctaaatcgtt tgatgatttt ttagagaaag caaagcagtt
    10201 gcatgttcag attgatttta gtcaaaagca tagccgtttt ttgatgacag atagaacgat
    10261 gataaaacca attcgagggc gccaactcag caaacgagat ctatatgatg aagaattttt
    10321 tagaacgcat tttgctaagc aagagattga aagtcgttta gaatttttgt taaaccgtgt
    10381 caattcttta gaagatttaa taacaaaagc aaaagaattg aatctaacca ttgacttaaa
    10441 acaaaaaatg taacttttat cctggaagaa aataatcaaa agataagttt gggtcatcaa
    10501 aaaataagtg ataagaaatt atatgatgtc aaattttttc aagattattt taaaaataag
    10561 gaagtcgttg cttcagaagg attagagaat ttacaggaac agtaccatgc tttccaagaa
    10621 gaacgagata aggataaagt atccactgaa gagattgaga aagcctttaa gacatttaag
    10681 gaaaaatgag ataccgttcg tgaatttgaa gtggaacttg cagagaacca aatagagaag
    10741 ctagttgata agggcgtcta tatcaaggtg tctttcggtg tcaaacagag cggtcttatt
    10801 ttcattccca actatcaatt ggatattatg gaagaagaaa atcataaaaa atataaagtc
    10861 tacattcgag aaacgtcttc ttactttgtc tataataaag aaaacatgga taataattgt
    10921 ttcatcaagg gtaggacctt aatcagacaa ttgagcaacg atagccaaaa actcccctat
    10981 agacgaccaa ctttaaaaag tcttcaagag aagatttctg aaattaatct tatgattgaa
    11041 ctatctaaca cgaacaaaca ataccaagaa atcaaagatg agcatgtatt agaaattgca
    11101 gagattgata tgaagctaga agaaacccaa gaaaaaatcg ccaccttaaa caagatggcg
    11161 gaagtcctta tcaatttgaa gagtgaagat catgagacta gaaaattagc taagtatgat
    11221 tttgaccaaa tgaacatgac ggaatcaata atgttagatc gactcaatac agatatttta
    11281 aaattacaac aggaacttgg taatgaaatt aataaatatg aggagatagc tagaagattg
    11341 gatttgtttg tgaaaattat taataccaat aaatttacag ttctaaaatt tcacgagaat
    11401 gccttactag aataatatta tttacgacta attagttaaa agatagagaa tcatttcatt
    11461 tattgtttac aagtttatca aaatggctag tatagtgtaa ttttaacttg tcttctccta
    11521 aaatatcgag aacttgtata gcttgtttca ttgtttcaat accactactt aattgacgtt
    11581 taaattcata gtaaccggtt gcatagagaa aaactgtctg ttcataaaag tttaattcat
    11641 tctctaacaa tccctttatc tcattaatta aataagagca attagaaaat tcttctttat
    11701 ctatgctgag aatgaaacaa tttatagcta gctgagt
//
LOCUS       DAVMCG010000051        11496 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVMCG010000051 DAVMCG010000000
VERSION     DAVMCG010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.052"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(166..1797)
                     /locus_tag="VYP66_001815"
     CDS             complement(166..1797)
                     /locus_tag="VYP66_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1851316.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGFGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2090..7030
                     /locus_tag="VYP66_001816"
     CDS             2090..7030
                     /locus_tag="VYP66_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1851317.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANPELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETAEAASAAKPEEK
                     ASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFALSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEP
                     KKDYLVGDNLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEAQELLAAKPNHPSGS
                     ALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKSAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7120..8316
                     /locus_tag="VYP66_001817"
     CDS             7120..8316
                     /locus_tag="VYP66_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1851318.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8452..8979
                     /locus_tag="VYP66_001818"
     CDS             8452..8979
                     /locus_tag="VYP66_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1851319.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDKSVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9056..9412
                     /gene="glnR"
                     /locus_tag="VYP66_001819"
     CDS             9056..9412
                     /gene="glnR"
                     /locus_tag="VYP66_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1851320.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9449..10795
                     /gene="glnA"
                     /locus_tag="VYP66_001820"
     CDS             9449..10795
                     /gene="glnA"
                     /locus_tag="VYP66_001820"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1851321.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10891..11010)
                     /locus_tag="VYP66_001821"
     CDS             complement(10891..11010)
                     /locus_tag="VYP66_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1851322.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3676 a         2118 c         2488 g         3214 t
ORIGIN      
        1 caggacagtc aaatcgattt ctaacaatgt tttagaaata gaggtgtact attctagttt
       61 caatatacta tatatctgca gaatactctt tcagtttcat tcagcctagt cttgcttagg
      121 aaaaagtaaa aagccatcca attatgatgg atagcttctt ggttcttaga tttgttctgc
      181 aaaaaccttt tcagcaaggt tcatagcgtg gtctgataca cgagtgtagt gtgagatgat
      241 gtcgataaag ttgaccccag cttgtgttga acattcgcct ttgttgaggc gtttgatgtg
      301 ggtttttctg agaacacgtt ctatcttatt gattgcttca tgacgttcta caagactgcg
      361 tgctttttca atatcattgt tttccacact atccagagca tctttgataa agtcactagt
      421 ttggcggtaa acttcctcta attctttcaa ggcggcatca gaaaattcaa catttttccg
      481 ttgaagatag tcagtcagat tgagtagagc ctccgtgtgg tctccaatcc gttccaaatc
      541 acgggaggaa tcaaggatat tggtaagcac ttcactttct ttttggctga gagcttcgct
      601 tgaaagggca atgagataac gtgttaattg ctcatcgatg gtgttaattg cttcttcggt
      661 tttatgccct ttttcagcaa ctttttcatc caaatcaatg atgtacttat aggaaaggtc
      721 aaaggcttta gcagcgtagt ttcctaagtg caagagctct ttcttagcat ttcctagagc
      781 gatagatggg gcctgtttga tgaaatgttc atcaagatat aagggttcgt atttgacaac
      841 ctcgtcctct ccaggaataa tcttggttac aaagtaagcc agagctccga taaatggaaa
      901 ttggacaatg gtgttggtaa tattaaaggt tccgtgagca aaggcgatgg tcatttccgg
      961 tgctagattt agcgtagctt caaaccaatg aatcaggaca gtaaaaggaa ctagaaaaat
     1021 aacgcagacg actgttccga taacgttgaa ggcaacatga gctcctgcta cccgtttagc
     1081 tgcaatatta gcccctaaag aggcaatgat ggctgtaatg gttgtcccga tattgtcacc
     1141 aaatagaact ggcaaagctc cctgtaggtc aattagattg ccggcgtaga ggttttgtaa
     1201 aatcccaatg gtagccgaag aagcttgaat tagcaaggtc aagccggtac cgacaaagac
     1261 acccaaaaca ggattcttac ttagctcaat catatagtcc ttaaagacct gtaaatcctt
     1321 gagtggagcc attgcgccgc tcatgagatt gagggcaaaa aagataccac cgaaaccaaa
     1381 gaggatgcgt ccgatattat tgactgtccg attttttgta aaaaagagac agacggcacc
     1441 gataaagagc ataggtaggg catagttacc taatttaaaa ccgatgagaa aggatgtgac
     1501 agttgtccca atattagcac ccatgacaat cccgatagcc tgacgtaagg ttaagagacc
     1561 ggcactgacc aggccgactg tgataactgt tacaccagaa ctagactgaa ttagagcagt
     1621 catcccaata ccaaccagaa ctccaaagaa aggattacta gtatatttgt caatgtaaaa
     1681 acgaaggcga tctccagcag cttgttgcaa accgtctccc atggtcttga tgctatataa
     1741 gaatagcccc agaccaccta aaaagtgaaa taaaatttcc tgccaattaa tggacatttc
     1801 tttttcctcc gaaaaataat cgcggaatat ctcctattct attttaaagg ataaaagtaa
     1861 atctaacaag tgttaatgtc aagtttgtaa aagaaaatta taattgataa gtgtattatt
     1921 tttaagagtt tttaacctta ttttagattt gtgcaaacag ttattgtttt ttgtctaaaa
     1981 atgttttagg ataaaaatgt gattatcatg gttctagagt ttgataaaaa actacagaat
     2041 ataaagcgct ttcttgaaaa caacaaaatc aatcttttag gaggagaaaa tgaagaatcc
     2101 attttttgaa agacgttgtc gttacagtat tcgtaagtta tcagtaggag cctgctcgct
     2161 gatgattggt gctgttttat ttgctggtcc agccttggct gaagaaactg cagttcctga
     2221 aaatagcgga gctaatccag agcttgtttc aggagagagt gagcattcga ccaatgaagc
     2281 tgataagcag aatgaagggg aacatgctag agaaaacaag ctagaaaagg cagaaggagt
     2341 agcgatagca tctgaaactg cagaagcagc tagcgcagct aaaccagagg aaaaagcaag
     2401 tgaggtggtt gcagaaacac catctgcaga agcaaaacct aagtctgaca aggaaacaga
     2461 agcaaagccc gaagcaacta accaagggga tgagtctaaa ccagcagcag aagctaataa
     2521 gactgaaaaa gaagtccagc cagatgtccc taaaaataca gaaaaaacat taaaaccaaa
     2581 ggaaatcaaa tttaattctt gggaagaatt gttaaaatgg gaaccaggtg ctcgtgaaga
     2641 tgatgctatt aaccgcggat ctgttgtcct cgcttcacgt cggacaggtc atttagtcaa
     2701 tgaaaaagct agcaaggaag caaaagttca agccttatca aacaccaatt ctaaagcaaa
     2761 agaccatgct tctgttggtg gagaagagtt caaggcctat gcttttgact attggcaata
     2821 tctagattca atggtcttct gggaaggtct cgtaccaact cctgacgtta ttgatgcagg
     2881 tcaccgtaac ggggttcctg tatacggtac actcttcttc aactggtcta atagtattgc
     2941 agatcaagaa agatttgctg aagctttgaa gcaagacgca gatggtagct tcccaattgc
     3001 ccgtaaattg gtagacatgg ccaagtatta tggctatgat ggctatttca tcaaccaaga
     3061 aacaactgga gatttggtta aacctcttgg agaaaagatg cgccagttta tgctctatag
     3121 caaggaatat gctgctaagg taaaccatcc aatcaagtat tcttggtacg atgccatgac
     3181 ctataactat ggacgttatc atcaagatgg tttgggagaa tacaactacc aattcatgca
     3241 accagaagga gataaggttc cggcagataa cttctttgct aactttaact gggataaggc
     3301 taaaaatgat tacactattg caactgccaa ctggattggt cgtaatcctt atgatgtatt
     3361 tgcaggtttg gaattgcaac agggtggttc ctacaagaca aaggttaagt ggaatgacat
     3421 tttagacgaa aatgggaaat tgcgcctttc tcttggttta tttgccccag ataccattac
     3481 aagtttagga aaaactggtg aagattatca taaaaatgaa gatatcttct ttacaggtta
     3541 tcaaggagac cctactggcc aaaaaccagg tgacaaagat tggtatggta ttgctaacct
     3601 agttgcggac cgtacgccag cggtaggtaa tacttttact acttctttta atacaggtca
     3661 tggtaaaaaa tggttcgtag atggtaaggt ttctaaggat tctgagtgga attatcgttc
     3721 agtatcaggt gttcttccaa catggcgctg gtggcagact tcaacagggg aaaaacttcg
     3781 tgcagaatat gattttacag atgcctataa tggcggaaat tcccttaaat tctctggtga
     3841 tgtagccggt aagacagatc aggatgtgag actttattct actaagttag aagtaactga
     3901 gaagaccaaa cttcgtgttg cccacaaggg aggaaaaggt tctaaagttt atatggcatt
     3961 ctctacaact ccagactaca aattcgatga tgcagatgca tggaaagagc taaccctttc
     4021 tgacaactgg acaaatgaag aatttgctct cagctcacta gcaggtaaaa ccatctatgc
     4081 agtcaaacta ttttttgagc atgaaggtgc tgtaaaagat tatcagttca acctcggaca
     4141 attaactatc tcggacaatc accaagagcc acaatcgccg acaagctttt ctgtagtgaa
     4201 acaatctctt aaaaatgccc aagaagcgga agcagttgtg caatttaaag gcaacaagga
     4261 tgcagatttc tatgaagttt atgaaaaaga tggagacagc tggaaattac taactggctc
     4321 atcttctaca actatttatc taccaaaagt tagccgctca gcaagtgctc agggtacaac
     4381 tcaagaactg aaggttgtag cagtcggtaa aaatggagtt cgttcagaag ctgcaaccac
     4441 aacctttgat tggggtatga ctgtaaaaga taccagccta ccaaaaccac tagctgaaaa
     4501 tatcgttcca ggtgcaacag ttattgatag tactttccct aagactgaag gtggagaagg
     4561 tattgaaggt atgttgaacg gtaccattac tagcttgtca gataaatggt cttcagctca
     4621 gttgagtggt agtgtggata ttcgtttgac caagccacgt actgttgtta gatgggtcat
     4681 ggatcatgca ggagctggtg gtgagtctgt taacgatggc ttgatgaaca ctaaagactt
     4741 tgacctttat tataaagatg cagatggtga gtggaagcta gctaaggaag tccgtggtaa
     4801 caaagcacac gtgacagata tcactcttga taaaccaatc actgctcaag actggcgctt
     4861 gaatgttgtc acttctgaca atggaactcc atggaaggct attcgtatct ataactggaa
     4921 aatgtatgaa aagcttgata ctgagagtgt caatattccg atggccaagg ctgcagcccg
     4981 ttctctaggc aataacaagg tacaagttgg ctttgcagat gtaccggctg gagcaactat
     5041 taccgtttat gataatccaa attctcaaac tccgctcgca accttgaaga gcgaagttgg
     5101 aggagaccta gcaagtgcac cattggattt gacaaatcaa tctggtcttc tttattatcg
     5161 tacccagttg ccaggcaagg aaattagtaa tgtcctagca gtttccgttc caaaagatga
     5221 cagaagaatc aagtcagtca gcctagaaac aggacctaag aaaacaagct acgccgaagg
     5281 ggaggatttg gaccttagag gtggtgttct tcgagttcag tatgaaggag gaactgagga
     5341 cgaactcatt cgcctaactc acgcaggtgt atcagtatca ggttttgata cgcatcataa
     5401 gggagaacag aatcttactc tccaatattt gggacaacca gtaaatgcta atttgtcagt
     5461 gactgtcact ggccaagatg aagcaagtcc gaaaactatt ttgggaattg aagtaagtca
     5521 ggaaccgaaa aaagattacc tagttggtga taacttagac ttgtctgaag gacgctttgc
     5581 agtggcttat agcaatgaca ccatggaaga acattccttt actgatgagg gagttgaaat
     5641 ttctggttac gatgctcaaa agactggtcg tcaaaccttg acgcttcgtt accaaggtca
     5701 tgaagtcaac tttgatgttt tggtatctcc aaaagcagca ttgaacgatg agtacctcaa
     5761 acaaaaatta gcagaagttg aagctgctaa gaacaaggtg gtctataact ttgcttcacc
     5821 agaagtaaaa gaagccttct tgaaagcaat tgaagcggcc gaacaagtgt tgaaagacca
     5881 tgaaactagc acccaagatc aagtcaatga ccgacttaat aaattgacag aagctcataa
     5941 agctctgaat ggtcaagaga aatttacgga agaaaagaca gagcttgatc gcttaacagg
     6001 tgaggctcaa gaactcttgg ctgccaaacc aaaccatcct tcaggttctg ccctagctcc
     6061 gcttcttgag aaaaacaagg ccttggttga aaaagtagat ttgagtccag aagagcttgc
     6121 aacagcgaaa cagagtctaa aagatctggt tgctttattg aaagaagaca agtcagcagt
     6181 cttttctgat agtaaaacag gtgttgaagt acacttctca aataaagaga agactgtcat
     6241 caagggtttg aaagtagagc gtgttcaagc aagtgctgaa gagaagaaat actttgctgg
     6301 agaagatgct catgtctttg aaatagaagg tttggatgaa aaaggtcaag atgttgatct
     6361 ctcttatgct tctattgtga aaatcccaat tgaaaaagat aagaaagtta agaaagtatt
     6421 tttcttacct gaaggcaaag aggcagtaga attggctttt gaacaaacgg atagtcatgt
     6481 tatctttaca gcacctcact ttactcatta tgcctttgtt tatgaatctg ctgaaaaacc
     6541 acaacctgct aaaccagcac cacaaaacaa agtccttcca aaacctactt atcaaccggc
     6601 ttctgatcaa caaaaggctc ctaaattgga agttcaagag gaaaaggttg cctttcatcg
     6661 tcaagagcat gaaaatgctg agatgctagt tggggaacaa cgagtcatta tacagggacg
     6721 agatggactg ttaagacatg tctttgaagt tgatgaaaac ggtcagcgtc gtcttcgttc
     6781 aacagaagtc atccaagaag cgattccaga aattgttgaa attggaacaa aagtaaaaac
     6841 agtaccagca gtagtagcta cacaggaaaa accagctcaa aatacagcag ttaaatcaga
     6901 agaagcaagc aaacaattgc caaatacagg aacagctgat gctaatgaag ccctaatagc
     6961 aggcttagcc agcctcggtc ttgctagttt agccttgacc ttgagacgga aaagagaaga
     7021 taaagattaa atatcgaaaa atcttgtgaa atctttcctt atatttccaa agtgtgatat
     7081 aatagtttcg aataaaataa ataaaggagt ttttgtaaca tggcaaaact tactgttaaa
     7141 gacgttgact tgaaaggtaa aaaagtcctc gttcgtgttg acttcaacgt accattgaaa
     7201 gatggcgtaa tcactaacga taaccgtatc acagcagctc ttccaactat taagtacatc
     7261 atcgaacaag gtggacgtgc aattcttttc tctcaccttg gacgtgtgaa agaagaagct
     7321 gataaagctg gtaaatcact tgctcctgta gcagcagact tggcagcaaa acttggtcaa
     7381 gatgttgttt tcccaggtgt cactcgtggt gctgaattgg aagcggcaat caacgctctt
     7441 gaagatggac aagttctctt ggttgaaaac actcgttacg aagatgttga cggcaagaaa
     7501 gaatctaaaa acgatcctga acttggtaaa tactgggcat cacttggaga tggtatcttc
     7561 gtaaacgatg cattcggtac agctcaccgt gcacacgcat ctaacgttgg tatctcagca
     7621 aacgttgaaa aagcagttgc tggtttcctt cttgaaaacg aaattgccta catccaagaa
     7681 gcagttgaaa ctccagaacg tccattcgtg gctatccttg gtggttcaaa agtttcagac
     7741 aagatcggtg ttatcgaaaa cttgcttgaa aaagctgata aagtccttat cggtggtggg
     7801 atgacttaca cattctacaa agcacaaggt atcgaaatcg gtaactcact tgtagaagaa
     7861 gacaaattgg atgttgcgaa agctcttctt gaaaaagcaa atggtaaatt gatcttgcca
     7921 gttgactcaa aagaagctaa cgcatttgct ggttacactg aagtgcgtga cactgaaggt
     7981 gaagcagttt ctgaaggctt ccttggtctt gacatcggtc caaaatctat cgccaaattt
     8041 gacgaagctt tgactggtgc caaaacagtt gtatggaacg gacctatggg tgtatttgaa
     8101 aacccagatt tccaagctgg tacaatcggt gtgatggacg ctatcgtgaa acaaccagga
     8161 gttaaatcaa tcatcggtgg tggtgactca gctgccgcag cgattaacct tggccgtgca
     8221 gacaagttct catggattag tacgggtggt ggagcatcaa tggaacttct tgaaggtaag
     8281 gttcttccag gacttgcagc cttgacagaa aaataagatt ttataaacaa atcaaagaag
     8341 agagggatga aagttcctct tttcttttgc ttaaaataaa aacgcttcct ctcaactatt
     8401 actcataaaa atcaccgatt tatgataaaa tggaaataga aagttgagat tatgagttat
     8461 tttaaaaaat ataaattcga taaatcccag ttcaaacttg gtatgcgaac ctttaaaaca
     8521 ggtattgctg tttttctagt tctcttgatt tttggctttt ttggctggaa aggtcttcaa
     8581 attggtgctt tgacagccgt ttttagcctg agggagagtt ttgataagag tgttcatttt
     8641 gggacttcgc gtattctagg aaatagtatc ggtggactct atgccttggt cttcttctta
     8701 ttaaatacct ttttccacga agccttttgg gtgaccttgg tagttgttcc aatctgcacc
     8761 atgttaacca ttatgacaaa tgtagccatg aataacaaag caggggttat tggtggtgta
     8821 gcagctatgt taatcattac cctatcaatt ccaagtggtg agacaatttc gtacgtgttt
     8881 gtgcgtgtat cagaaacgtt tatgggagtt tttgtcgcaa ttattgtaaa ttacgatatt
     8941 gatcgtattc gtctcttttt agagaaaaaa gaaaaataat gttacatttt ataacattat
     9001 caattgacgt ttgtcttttt ttagactata atagacagaa agaaggaaat tgtaaatgaa
     9061 ggaaaaagaa tttcgccgaa atatggctgt ttttcctatc ggcagtgtta tgaagttgac
     9121 cgatttatcg gcgcgtcaga ttcgttatta tgaagatcaa gagttgatca agcccgatcg
     9181 aaacgaagga aatcgtcgca tgtattcctt gaatgacatg gatcgtctgc ttgaaatcaa
     9241 agattatatc tctgaaggtt ataatatcgc tgccattaag aaaaaatatg ctgaacgtga
     9301 agcgaaatcc aagaaagcgg ttagtcagac tgaagtacgt cgtgcacttc acaatgaact
     9361 cctccaacag gggcgttttg cttcagtaca gtcacctttt ggtcgcggtt aggcaaccgc
     9421 aagtagtcat agattaagga gaaaacttat gccaatcaca gctgcagata ttcgtcgtga
     9481 agtcaaggaa aaaaatgtta cctttattcg tcttatgttc tcagatattt tgggaaccat
     9541 gaaaaacgtc gaaattcctg ctacagatga acagttagat aaggtcttat cgaacaaggt
     9601 tatgtttgat ggatcttcta ttgaaggttt tgtacgtatc aatgagtcgg atatgtactt
     9661 gtacccggac ttggatacat ggacagtctt cccttgggga gatgaaaatg gaagtgttgc
     9721 aggtctgatc tgtgatgtct atacaacaga aggtgaacca tttgcgggtg accctcgtgg
     9781 taatttgaaa cgagctcttc gtcacatgga agaagttgga ttcaaatcct tcaaccttgg
     9841 tccagagcca gaattcttcc tatttaagtt ggatgaaaat ggggacccaa cacttgaagt
     9901 gaatgacaag ggtggctact ttgatttggc acctactgac cttgcggaca acacacgtcg
     9961 tgagattgtg aatgtcttga ccaaaatggg atttgaagta gaagcgagtc accacgaggt
    10021 tgcggttgga cagcatgaga ttgactttaa gtacgatgaa gttctccgtg cttgtgataa
    10081 gattcaaatc tttaaacttg ttgttaaaac cattgctcgc aaacacggac tttacgcaac
    10141 atttatggcg aagccaaaat ttggtattgc tggctcaggt atgcactgta atatgtcctt
    10201 gtttgatgca gaaggaaata acgccttctt tgatccaaat gatccaaaag gaatgcagtt
    10261 gtcagaaaca gcttaccatt tcctaggcgg tttgatcaag catgcttaca actatactgc
    10321 catcatgaac ccaacagtta actcatacaa acgtttggtt ccaggttatg aagcgcctgt
    10381 ttacattgct tgggctggtc gtaaccgttc gccacttgtg cgcgtacctg cttcacgtgg
    10441 tatgggaact cgtcttgagt tgcgttcagt ggatccaatg gcgaaccctt acgttgctat
    10501 ggctgttctt ttggaagttg gtttgtatgg tattgaaaat aaaatcgaag caccagctcc
    10561 tatcgaagaa aatatctaca tcatgacagc agaagagcgc aaggaagctg gtattacaga
    10621 ccttccatca actcttcaca acgctttgaa agctttgaca gaagatgaag tggttaaagc
    10681 tgctctcgga gatcacatct acactagctt ccttgaagcc aaacgaatcg aatgggcaag
    10741 ttatgcaacc ttcgtttcac aatgggaaat tgataattat ttagaccttt actaatacta
    10801 atatagaaga aagattgcct gtgggtaaac agtcacacag cagtctaagc catcaaatac
    10861 ctataaccct taaaatagcg atttcggtcg ctatttattt ttcgaaaaat cctcttgact
    10921 cttttgcgaa ttagatttat catcagacgt gtagaagaaa atcaaggagt cactatggaa
    10981 aaattcaatt tcaaaaacaa tatcgggcaa gaaaacaagt tacttcaaat cgaaatctac
    11041 aagtttacta acttttacaa gcttcaaaat tacacatctg taaatatttt ttcgaaagat
    11101 atatttgaag ccatagtaaa ttgagactag aatagtacac tacatctgct aaaaatttct
    11161 agaaactaat ttaactttcc taatcgattt gtttacatct tatttcaatc tactatatta
    11221 tctcaataaa tgatgatggc gactgttttg tttgtgcttg tcgatttttg aatccctgat
    11281 cgagcggaag aatatttctg ccgaggttgc caaggggaaa atactgaaga tattgaattt
    11341 tatgataaac aattacaggc agaaaaggtg gaggttttga atattcgatt ggaagtaaaa
    11401 aattgaatta tctacaatct catcaacaat aaacctattt caaccccatt atctataggc
    11461 gtatttttac gcctttttat atacttgaag cacata
//
LOCUS       DAVMCG010000052        11097 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVMCG010000052 DAVMCG010000000
VERSION     DAVMCG010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11097
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.053"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            19..380
                     /locus_tag="VYP66_001822"
                     /pseudo
     CDS             19..380
                     /locus_tag="VYP66_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            915..1607
                     /locus_tag="VYP66_001823"
     CDS             915..1607
                     /locus_tag="VYP66_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1851323.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1660..4071
                     /locus_tag="VYP66_001824"
     CDS             1660..4071
                     /locus_tag="VYP66_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1851324.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGRI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDEKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQVAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4321..5022
                     /locus_tag="VYP66_001825"
     CDS             4321..5022
                     /locus_tag="VYP66_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851325.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPAQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5024..7732
                     /locus_tag="VYP66_001826"
     CDS             5024..7732
                     /locus_tag="VYP66_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1851326.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMETTANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKAL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVATVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7828..8319)
                     /gene="tpx"
                     /locus_tag="VYP66_001827"
     CDS             complement(7828..8319)
                     /gene="tpx"
                     /locus_tag="VYP66_001827"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1851327.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8442..9371)
                     /gene="psaA"
                     /locus_tag="VYP66_001828"
     CDS             complement(8442..9371)
                     /gene="psaA"
                     /locus_tag="VYP66_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1851328.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9403..10251)
                     /locus_tag="VYP66_001829"
     CDS             complement(9403..10251)
                     /locus_tag="VYP66_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1851329.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10248..10970)
                     /locus_tag="VYP66_001830"
     CDS             complement(10248..10970)
                     /locus_tag="VYP66_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1851330.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3251 a         2066 c         2531 g         3249 t
ORIGIN      
        1 ttaaaaagac ttgctttaat tagtggtatc gtcggtcttg tgggaggaat tttacttctt
       61 attggtcctt ttgtcttgtt gggaatagcg gtaaacacag ctgctacaac tcttaatgga
      121 ggagctactg caggggcttt ttcaggtgta gccttactct tgaatgcctt gaagattgca
      181 aatcttgttc ttggtatcat tgctattgtt tactataaag gagataagcg tgtaggtgca
      241 gctccgtctg tactaatgat tgtttctggt ggagttagtc tcattctatt ccgttcttag
      301 gatgggttgg ggggattttt gctattatcg gaggatctct attcctttca acattgaaga
      361 aattcaaatc agaagaataa aaggtatttt agcatgaaaa gaacaaaaaa gtttatcggt
      421 ataggagtag ctctattatc tctttctctt ctagttgcat gtggaacata aagttcaaag
      481 aatacttcaa caagtaatga tgagaagaca gtagcaacat ccaatagttc aaaagaaaca
      541 atcactttcg atacaccggt tgtaacagac gatgcgattg aatcaatacg cacttatgca
      601 gattatatag atctttataa aaatattttt gatgattatt ttactaaagc tgaggaaggt
      661 ttcaaaggca tagctatgga aaataatgac tcgtttacta aactaaaaga gtcaactcaa
      721 aaattattcg atgcgcagaa aaaaaggtta aataatgaag atagaataga aacaaccaaa
      781 aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct ttttggtttt gactagcttt
      841 tttgtgaaaa attgtgtaaa atagaataga taaacgaggg gaaacctcgg aaaatttaaa
      901 ggagaatcca tctaatggta aaattggttt ttgctcgcca cggtgagtct gaatggaaca
      961 aagctaacct tttcactggt tgggctgatg ttgatttgtc tgaaaaaggt acacaacaag
     1021 cgattgacgc tggtaaattg atcaaagaag ctggtatcga atttgaccaa gcttacactt
     1081 cagtattgaa acgtgctatc aaaacaacta acttggctct tgaagcttct gaccaattat
     1141 gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt ttgactggta
     1201 aaaacaaagc tgaagctgct gaacaatttg gtgatgagca agttcacatc tggcgtcgtt
     1261 catacgatgt attgcctcca aatatggacc gtgatgatga gcactcagct cacacagacc
     1321 gtcgttatgc ttcacttgac gactcagtaa tcccagatgc tgaaaacttg aaagtgactt
     1381 tggaacgtgc tcttccattc tgggaagata aaatcgctcc agctcttaaa gatggtaaaa
     1441 acgtattcgt aggagctcac ggtaactcaa tccgtgccct tgtaaaacac atcaaaggtt
     1501 tgtcagatga tgagatcatg gacgtggaaa tccctaactt cccaccattg gtattcgaat
     1561 tcgacgaaaa attgaacgtt gtttctgaat actaccttgg aaaataaaaa attgtaagcc
     1621 taggattgat ttctaggctt tttatgttag tatggaagta tgataaggaa taaaaaacaa
     1681 gattatgtac tggcctacaa acaaccagct tcaaccactt acatgggttg ggaagaagaa
     1741 gctttaccga taggtaatgg ttctttagga gcaaaagtat ttggccgtat aggggctgaa
     1801 cggattcaat ttaatgaaaa aagtctctgg tctggaggtc cacttcctga tagttcagat
     1861 tatcagggtg gaaatcttca ggatcagtat gtttttttag ctgagattcg gcaggctttg
     1921 gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat tgggccaaaa
     1981 acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt cagccagcaa
     2041 ggtacgactt tgtctcaggt gacggactat cagagacagc tgaatattag taaggcactt
     2101 gtgacgactt cttatgtcta taagggaacg cgatttgaac gtgaagcttt tgcgagtttt
     2161 ccagatgatc tcttggttca gcgttttact aaggaagggg cggaaactct agattttact
     2221 atagaactat ccttgacctg tgatttggct tctgatgaaa agtatgagca ggaaaaatct
     2281 gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa gggaagagtt
     2341 aaggataatg atctgcggtt tgctagttat ctagcttggg aaacggatgg agatattaga
     2401 gtttggtcag atagggttca gatatcagga gccagttatg ccaatctctt cttggccgct
     2461 aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga tttagagcaa
     2521 caggtgatag acttggtgga cacagctaaa gaaaagggct atacccaatt gaaatcaagg
     2581 catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga agctgatgtt
     2641 gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg gcaggctttg
     2701 gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag agactgccca
     2761 gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc tccttggaat
     2821 tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta tgttaccaat
     2881 ctcctagagg cggtctttcc ggtcatcaac tatgtagatg atttgcgtgt ctatggtcgt
     2941 ctagcggctg taaagtatgc aggaatcgtc tctcagaaag gtgaggaaaa tggttggttg
     3001 gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta ctattggggt
     3061 tggtcaccag ctgccaatgc gtggatgatg caaaccgttt atgaagccta ttcattttat
     3121 agggaccaag actatctcag ggagaaaatt tatcccatgt tgagggaaac ggttcgtttt
     3181 tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtgtcttc tccgtcttat
     3241 tctccagaac atgggccgat ttcgattggc aatacctatg accaatctct gatttggcag
     3301 ttatttcatg attttattca ggttgctcag gaattgggac tggatgagga cttgttgact
     3361 gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc tggtcgaatc
     3421 agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga ggcccagcat
     3481 cggcacgctt cccatctagt gggactctat cctggcaatc tctttagcta caagggacaa
     3541 gagtatattg aagcggcacg tgctagcctc aatgatcgtg gagatggcgg cacaggctgg
     3601 tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggcaatcg agcccataaa
     3661 ttattggcag agcagttaaa aacatccacc ttgccaaatc tttggtgtag ccatcctcct
     3721 tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt actccagtct
     3781 catgcagctt atctggtacc tctagctgcc ctacctgatg cttggtcaac aggttctgtt
     3841 tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga taaaaaactc
     3901 ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta tccagatatt
     3961 gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat ggggaaagat
     4021 tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta agaagatgtt
     4081 ataaggcagt aatttgaaac ttccttttaa taaggattta agaatatagg cagtttccaa
     4141 ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa tcaaagagca
     4201 caaactagga agctagccgc aggttgctca aaacagtgtt ttgaggttgt agatggaagc
     4261 tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag ggtgggtctg
     4321 atggcttata ttgagatgaa acactgttac aagcgttatc aggttgggga cacggagatt
     4381 gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat tatccttggt
     4441 gcttcaggtg caggcaagtc aacagttctt aaccttcttg ggggaatgga taccaatgat
     4501 gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca ccagcgcacc
     4561 aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt ttctaatctg
     4621 acagctaagg aaaatgtgga actggcttct gaaattgtga cagatgcctt gaatcctgct
     4681 caggttttga cagatgtagg tctggctcat cgtctcaata actttccagc ccagctttct
     4741 ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc taaaattctt
     4801 ctttgtgatg aaccgactgg agccttggat tatcagacgg gcaagcaggt tttgaaaatt
     4861 ctccaagata tgtctcgtca aaagggagcg acggtgatca tcgtgactca taatggagct
     4921 ttggcgccca ttgctgatcg cgtgattcat atgcacgatg ccagtgtcaa ggatgtggtg
     4981 ctcaaccagc atcctcagga tattgacagt ttggagtact agcatgatca agcgaaaaac
     5041 ttattggaag gacttaattc agtccttcac aggctccaag gggcgttttt tatccatctt
     5101 gatcctgatg atgttgggat ctctagcctt agtaggcctc aaagtaacca gtcccaacat
     5161 ggagacgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg cagtcatgtc
     5221 taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg gcgcagaggt
     5281 cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca ttcggctgta
     5341 ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc ctcagtcaga
     5401 caaggaaatc gctttggcca ctcatttgca aggccaatac agcgtgggac aggagattag
     5461 ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata ccattactgg
     5521 ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag gaagtggaag
     5581 tgggactctg acagcctatg gggtgatttt acctagtcaa tttgatcaga aagtctacaa
     5641 tatagctcgt ttgaaatatc aagatttagc aggtttaaat gccttttcat cagcttatga
     5701 agaaaaatcc aagcaacatc aggaagagct tgaacaaatt ttatcagata atggcaaggt
     5761 acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc aagagaccct
     5821 tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg ctcaagctcg
     5881 tatacaggct caagaaagtc aactagcctt gtttcctcaa gttcagagag agcaggctag
     5941 tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaggccaaac taaagcaagc
     6001 tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa catcagcaag tcttggacga
     6061 tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg gtcagggcta
     6121 tcttatgtat agcaatgctt catccagtat tcgagcagtg ggcaatatct ttcctgtggt
     6181 actttatgcc gtagcagcca tggtgacctt tacgaccatg actcgctttg tagacgaaga
     6241 gcgaactcat gcagggattt ttaaggcctt gggttatcgt agtaaggata ttatcgccaa
     6301 gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta gtatacttgg
     6361 tcattatttg ctagccaatg taatttcaag tgtcattaca aaaggcatgg tggtgggaga
     6421 aactcagatt cagttctatt ggacctatag cttactagct cttgtcttga gcttgttggc
     6481 gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgacgaag cagcccagct
     6541 tctacttcct aaacctcctg tcaaaggagc taaaatctta ttggagcgta tcggttttat
     6601 ctggcgtcgt ctcagtttta ctcataaggt aacagctcgc aacatctttc gttataagca
     6661 gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct ttgcaggttt
     6721 gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa tccaacagta
     6781 tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag agctagcaga
     6841 agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaag cgctagacaa
     6901 ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt atgatgatag agaaggaaga
     6961 tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa aagatggcat
     7021 cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga ctttagaaat
     7081 tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc actttattta
     7141 tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca acacttatct
     7201 ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct tgcttatgaa
     7261 tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc attcgactct tcgactctat
     7321 cgctagctca ctcaatcaga ccatgaccat cttggtcatc gtatcggttc tattagctat
     7381 tgtcatcctt tacaatctga ccaatatcaa cgtagctgag agaatccgtg aactctccac
     7441 tatcaaggtt ctcggttttc ataataatga agtcaccctc tacatttacc gtgagacgat
     7501 tgtgctgtcc cttgtgggaa tcgtacttgg tctggtagct ggtttctatt tacaccaatt
     7561 tttgattcaa atgatttcgc ctgcgactat tctcttttat ccgcaggtag gctgggaagt
     7621 ctatgtaatc ccagtggcaa cagtaagcat cattttgacc ttgcttggtt tcttcgtcaa
     7681 ttattatctg agaaaggttg atatgttaga agccctgaaa tctgtagagt aaggtagtta
     7741 tttttagctg attgaacttc tatttactaa tattcaaaaa tcctccgttt caaagagcag
     7801 ggagctcttt gtgacagagg attttttcta tagggcttta gcagctgcaa ttgcggcttc
     7861 gaagtttggc tcagaattga tattatccac gtattcaacg tagcgaatcg tattgtcagt
     7921 atcgaggaca aagactgcgc gtgctaatag gtgccattcg ttgatcaaga gggcataatc
     7981 gcgcccgaaa gaatggtcaa agtagtctga aagcataatg gcattgtcaa ggccttcagc
     8041 accgcaccaa cgtttttgag caaaaggtag gtccattgaa acagtcaata cgaccgtgtt
     8101 gtccagtcca gccaattctt cattaaaacg acgtgtttga gttgagcaga tacctgtatc
     8161 gatagaagga acgacactca agactttttt cttgccatca aaatcagcca gagatttttt
     8221 agaaagatct gttgtagtaa gagaaaaatc aagcgccttg tcgccgactt gtagttgttt
     8281 acctgtaaag ctcacaggat ttccgagaaa agttaccata ggatactcca atcttttttc
     8341 ttccattgta tctaaaacag tcagaatttt ccaatgattt gaccggaaat gtgtgcatag
     8401 aaaaaacgcc agctcacatg agaatgacgt ttttcagagg cttattttgc caatccttca
     8461 gcaatcttgt caaggttgta tttcatcatg ctgtagtagc tgtcgccttc tttaccttgt
     8521 tctgcgatag agtcagtaaa gatttgtgcg tagattggga tgtttgtgtc ttgagaaaca
     8581 gttttcattg gacggtcatc cacacttgat tctacaaaga gtgatggaac ttttgtttgg
     8641 cgaagttttt caaccaaggt cttgatttgt tcaggagttc cttcttcttc agtattgatt
     8701 tcccagatgt aggcacttgg gacaccatag gctttagaga agtatttgaa tgctccttcg
     8761 ctggttacaa tgagtttctt ttcagcaggg atcttattaa atttatcctt actttcttta
     8821 tcaagtttgt ctaacttatc agtatattct ttgagatttt tttcatagaa ttctttattg
     8881 ttagggtctt tggcgctcaa ttgtttggcg atatttttag caaaaataat accgttttca
     8941 aggttaagcc aagcgtgtgg gtcttctttt cctttttcat tttgaccttc aaggtagata
     9001 acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt cagttttctt ggcattttct
     9061 accaattttg taaaccaagc attgccacct gtttcaaggt tgataccgtt atagaaaatc
     9121 aaatcagcct cagaagtttt cttaacgtct tcaggaagtg gttcgtattc gtgtgggtct
     9181 tgcccaatcg gaacgatact atgaaggtca attttgtcac cagcaatatt tttagtaata
     9241 tcagcgatga ttgagtttgt agcaacaact tttagttttt gaccagaagt tgtatctttt
     9301 tttccgctag cacatgctac aagaatgatt gcagaaagaa agagaacgag taatgtacct
     9361 aattttttca ttagatcctc caatttatta gggctttgcc ccttatttta acaaatgttt
     9421 atttttcagt ttcaaatatc gttgtttggg agcgataaag aagctaatga gaaagaaact
     9481 agcagctgta agcacgatac tagaacctgc cgcaacatta aaactatagc caataaagag
     9541 tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg aaaatcatac ttttcagact
     9601 attagcatac agataagcag ttgcagctgg ggtaatcagc atggctacaa tcaggatagt
     9661 tccgacactt tgcatggctg tcacagacac gagagtcagg agtaccatga gaaggtagtg
     9721 atagaaattg acaggcattc ccatggcttt agccaagagt tcatcaaagg aagttatcaa
     9781 gagttgcttg aagaaaatcc agattaacaa gaggatggct gcccccacac ccatagtaat
     9841 aaacatatcc gtatcttgga cggccaggat attaccaaaa aggatatgga aaaggtcagt
     9901 tgaactttta gcgacaccaa tcaagatgat accgagggct aagaaagaag aaaaggtaat
     9961 gccgatggcg gtatcgcttt tgataatcga gtttcctttg atgtaggtaa tgatgatggc
    10021 agctagcaat ccaaagacaa tggctccgat aaagaagtca aggcccaaga tgaaggagag
    10081 ggctacacct ggtaagacag catgtgaaat ggcatctccc atgagtgaca tcccgcgtag
    10141 aataatgaaa catcccacag ctccagctac aatcccgacg acaatagctg ttatcaaggc
    10201 attttgtagg aaatggaatt tttgcaatcc atcgataaat tctgcaatca taggtcacct
    10261 ccattgaaaa agagttgatt accgtaagct tcttttagat tggtttcggt aaaagtttct
    10321 tttgttggac caaaggcaat cacttctcga ttgacaagta agacttgatc gaagtagtgg
    10381 ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct tcccagcttt tttcaaatct
    10441 ctcagcgtat tcatgatgat ttcctcactg acagagtcaa tcccagcaaa gggttcatcc
    10501 aagaggatat agtcggcttc ctgcaccaaa catctggcaa tcaagacccg ctggaattga
    10561 cctccagaca gttgactaat ttgacgttca gcgtagtcag ctaggccgac gatttcaagg
    10621 gcctcttgca ctttcttcca atgtttagcc tttaaacttc gaaagagagg aatagaggga
    10681 aatagtccta acgagacgca ttccttgacc ttgatgggaa agttgtagtc gatattgatt
    10741 ttttgttcga cataggcaat tcggtgtaag gattttttaa cttccttgtc atcgagaaat
    10801 gcctgacctt gatgtgggat aattcccaac atacctttta atagtgttga tttcccagcg
    10861 ccgtttggac caatgatgcc ggtaattgtt ggtccatgga gcactagtga aatatcctta
    10921 agtgccaacg tttctttgta ggagacactg aggttttcga tacgtatcat aaacttgtat
    10981 tcctcctgtc tcttaatata cattaaaaaa aaaattaagt caagttaatt tttgaaaaaa
    11041 ttaaaataat aactgaaaaa tagattctaa agataacttt caggataaat ttctaaa
//
LOCUS       DAVMCG010000053        10875 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVMCG010000053 DAVMCG010000000
VERSION     DAVMCG010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.054"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            117..281
                     /locus_tag="VYP66_001831"
     CDS             117..281
                     /locus_tag="VYP66_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1851331.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            365..931
                     /gene="amaP"
                     /locus_tag="VYP66_001832"
     CDS             365..931
                     /gene="amaP"
                     /locus_tag="VYP66_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1851332.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            943..1113
                     /locus_tag="VYP66_001833"
     CDS             943..1113
                     /locus_tag="VYP66_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1851333.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1152..1760
                     /locus_tag="VYP66_001834"
     CDS             1152..1760
                     /locus_tag="VYP66_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1851334.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1791..1994
                     /locus_tag="VYP66_001835"
     CDS             1791..1994
                     /locus_tag="VYP66_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1851335.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2104..2376)
                     /locus_tag="VYP66_001836"
                     /pseudo
     CDS             complement(2104..2376)
                     /locus_tag="VYP66_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2580..2867
                     /locus_tag="VYP66_001837"
     CDS             2580..2867
                     /locus_tag="VYP66_001837"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1851336.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3145..3915)
                     /locus_tag="VYP66_001838"
     CDS             complement(3145..3915)
                     /locus_tag="VYP66_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1851337.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTTKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3930..4778)
                     /locus_tag="VYP66_001839"
     CDS             complement(3930..4778)
                     /locus_tag="VYP66_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEV1851338.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4775..6250)
                     /locus_tag="VYP66_001840"
     CDS             complement(4775..6250)
                     /locus_tag="VYP66_001840"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1851339.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHTLGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6574..7929)
                     /locus_tag="VYP66_001841"
     CDS             complement(6574..7929)
                     /locus_tag="VYP66_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1851340.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNYLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7939..8256)
                     /locus_tag="VYP66_001842"
     CDS             complement(7939..8256)
                     /locus_tag="VYP66_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1851341.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8273..8590)
                     /locus_tag="VYP66_001843"
     CDS             complement(8273..8590)
                     /locus_tag="VYP66_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1851342.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8605..9501)
                     /locus_tag="VYP66_001844"
     CDS             complement(8605..9501)
                     /locus_tag="VYP66_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1851343.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9504..10766)
                     /locus_tag="VYP66_001845"
     CDS             complement(9504..10766)
                     /locus_tag="VYP66_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1851344.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         3739 a         2187 c         1678 g         3271 t
ORIGIN      
        1 aagaatttga ttttttgata ttaaaataaa aaaggagggt aggcagtgtt gtgatcaatt
       61 attgctggag gtcttattgg tctcttggca ggtaaaatca ctaaaaaagt agttctatgg
      121 gaatcatcgc aaatgtattc gctggtttag tcggggcata tgcaggacaa tctcttttag
      181 gtagttgggg tccatcaatc gctggaatgg ctttgctccc atctattgta ggtgcagcga
      241 ttgtgattac tgtagtgtca ttctttacag gtagaaagta aacttttcgc cagtaaagtt
      301 agcaaactat ttttaaatca atgacgggaa aaatagttta aatgttaaat cgaaaggatt
      361 gtatatgtca aaagcaaaga aaatatgttt cattattttc tgtattttaa tcttgacaat
      421 tttccttcct gttttgatag attatcatca agttagtgat ctaggtattc atctacttag
      481 ctggagacag aactccgtag ttgaattcta tcttgctaga tatgtctttt gggggacagt
      541 ggttctatca actttagttt tattatccat tttagttgtg atgttttatc ctaaacgtta
      601 cttggaaatc caacttgaaa ctaaaaacga tacattaaaa ttaaagaatt cggcaatcga
      661 aggttttgtt agaagtttgg tgagtgatca tagattgatc aagaacccaa ctgttcatgt
      721 aaatttacga aaaaataaat gtttcgttca tgtagaaggt aaaattcttc cttcagacaa
      781 catcgctgac agatgccaaa taattcaaaa tgaaataact aatggattga agcagttttt
      841 tggtattgag cgtcaagtaa aacttgaagt tgcagtaaaa aattaccaac caaaacctca
      901 aaacaaaaag actgttagtc gtgtgaagta aggaagtaaa aaatggaatg gcttaaacaa
      961 tatcgatatc caattatcgc tggtctcata ggcgtatttc tggcttgttt gattgtctcc
     1021 tttggcttct tcaaaacaat atttgtattg attttaggag cactgggagt tgcagctgga
     1081 ttatatatcg aaaaaaacta tatagataaa taaaaaaata aaaattacta atttaattaa
     1141 aggagtttca tatgtcaaac gaaaaaaaca caaatactaa cgtagaaaag aaagatgcta
     1201 ctgttgtagc tcacgaaatc aaaggggaac ttacttacga agataaagtt atccaaaaaa
     1261 tcattggtct ttcactagaa aacgtttcag gtcttttggg aatcgatggt ggtttcttct
     1321 caaatcttaa agaaaaaatc gttaacagcg atgacgtaac aagtggtgtt aacgtagaag
     1381 ttggtaaaac acaagttgca gttgacttaa acgttattgt tgagtaccaa aaaaatgttc
     1441 cagctttata ttcagaaatc agagaaatcg tatcttcaga agttgctaaa atgactgact
     1501 tggaaattgt tgaaatcaac gtaaacgttg tcgacatcaa aactaaagaa cagcatgaag
     1561 cagactcagt aagccttcaa gatcgcgtat ctgacgttgc tgaatcaaca ggagaattca
     1621 cttcagaaca attcgaaaaa gctaaatctg gtcttggatc tggtttctca actgttcaag
     1681 aaaaagttag cgaaggtgta gaagctgtta aaggggcagc aaatggtgta gtatctcacg
     1741 aaaacactcg tgtaaactaa gataaaataa atataacagg agaaattatc atgtcagtag
     1801 aagaaaaatt aaatcaagct aaaggttcta ttaaagaagg tgttggaaaa gccatcggtg
     1861 atgaaaaaat ggaaaaagaa ggagcggctg aaaaagttgt ttctaaagtt aaagaagttg
     1921 ccgaagacgc taaagacgct gtagaaggtg ctgtagaagg tgttaaaaac atgttgagtg
     1981 gcgacgataa ataaggttaa aagttacttt atctttttgg taacattagt caaaagagtc
     2041 tgagtcgaga tgattctcag aaaacaaaaa gctagagatt cccaattgcg gaactctagc
     2101 tttttaattt tgcctctttc tcttattata tttcagcagg ttgttggcca tgagtatgaa
     2161 tcccatgtca attctcactt gacgcttacc tctcagatga catctcttat aacccaaaca
     2221 aacctttatc tgcccaaaga cagatttcat atcaatctta cgtttagcga aaatttgtct
     2281 acccttggaa gataaaagtg cctgatattc tttagttttt aaacactggt aacgttcatt
     2341 catatacagt ctcttttgag gggctgattc aggttcataa tcgcagtcaa cattgatttc
     2401 aaggctgttt gctttctatc tccccttttt catgatatat tttcgtacag gtgcttcaat
     2461 agtttctata gtaaaatgaa ccaaaaatag tacacgttgc ggtataatgt tcttatggca
     2521 tattcattag attttcgtaa aaagttctct cctatttgtg agcgaacagg tatagtcaat
     2581 tgattgtcag tttgaagacc aagagtcgta aggcaaagga tatggcagaa tccatccaag
     2641 ggtggctggc acaatttcta gtgaacctct ttaaatctat tacgtttgac tgtggaaaag
     2701 agttttcaaa atggaaagat atttccaatc atcacgatag tgagagcttt tttgcgaatc
     2761 taggatgtcc aagacagcgg tgtctcaacg aacattcaaa tagactttta aggtgtcatg
     2821 acttgccaaa gcagacagat ttcaacgaag tcagtcaaga attttaggct gggtaaaaac
     2881 tcaatttcag gagaaaatga aataaatatt cccacaataa aatgcatagt atcaaagttt
     2941 ttccaacacc tgatattatg cattttttaa ttttaaagac tttttcccag cctcaagaaa
     3001 tcacatccca cctaaatcct ttggatacca aatacctcat caggtatttt ctgagttggt
     3061 aagactgtct agcttaattt gacaaatgga gggcgttaaa tccagttttt acaggaagtc
     3121 tatttaaata ttttcacact gaccttacaa aatatgaaat aaattatata aagtcattcc
     3181 catgacaaag aataacatcc ctttaaaaca gtatcttacc caattttcag gtaagacttt
     3241 tgatacaacc gtccccaata cccctccgca tatagaagca agaaaaataa ctggaacagg
     3301 tgctaaatga tactgattta aacctgtaac cacaacaatt gtagccaaat gagacaactg
     3361 ggaaaagaaa ataattgcaa gagaatacat cgttgcttct tttatcgaaa tagaaaaaaa
     3421 caccatcaat aaagatacat tgagcggacc accaccaatc cctaaaaaac tagaaatcaa
     3481 gcccaataga agaccacaaa tcatatagaa tcctatctta tcaaattgat aagttttttt
     3541 aaaatctgtt aaaacaaatg atacaagtag catcacaaat agtaaaatca tttgaacaat
     3601 ggatactagc cgtactgata attgagataa caaaacttga aaaataagat gacctagaaa
     3661 ccctcctaaa acagaagaaa aggataccgt aaaaatcaat ctccatttta tctctttact
     3721 ttgtgaaaat cttttggttg ttgaaataat cgccattata aaaacagaga aactagaata
     3781 aaaagcaata tcactgaccg aatggtatcc aaaactatcc ataagtggct taattataat
     3841 tccaccaccc atgcctgata tagaacccaa tccactagct attataatga ttagaaaata
     3901 aataatctca accacttttt aagtccatcc tattctttca aacatctaaa acctagatgg
     3961 ctactagtgg aagtagaaat acatccattt ctagcagcta ctcggtatcg attacaataa
     4021 gaacaatgac ataaaaagga acctcctctg atagcatact cctcatcttg tatcccatat
     4081 tttggtaact catagtcatc ttcattaaaa ctagctaata aggtatatct cggattgcga
     4141 caccattccc aaacattccc aatcatttga tatagaccaa aatcattagg taaaaattca
     4201 tagacaggag ccgttcctat aaatccatct aaggcagtat tttcataagg aaatcttcct
     4261 tgccaagtat tggcatgata atatccacct tctaaaagag tatctcccca aggatattca
     4321 gattgtcttc ctcctctagc agcatattcc cactgtgctt cagtcggtaa agacattccg
     4381 ctccaattac agaaagccaa tgcatcttct aaagcaacat gaactactgg atggtcttct
     4441 aaacccacta gattactgtt ctcaccgtag ggatgtttcc agcaagcgtt cgaaacttgt
     4501 aaccaccacg gagccccagc aggatgagga tatccctccc tttctgcctc cggaacgaac
     4561 aatataaaaa caaaagacca ctcttgtcgc tcagctagtg ttttatagcc tgtttctttc
     4621 acaaattgag caaattcttg attcgtaact ggagtatccg caatggaaaa atcctttaca
     4681 ctaacagcga cttgaggacc ttcaaaatca tctaaaaagc cctcttcaga atttgttccc
     4741 atcataaatg tcccaccctt gatttttttc attttcatga ttgactatcc cccgttttcg
     4801 ttagagttgg cgttatttta gaaagttcaa caggaactaa ctcttcatcc acaacaaaac
     4861 cttcttctct atatctaaga aagtctacta attttttctt catctgacga acaataggtt
     4921 gatatttttc acttggatac aaatcattca tttcatgcgg atcttttttc atatcaaata
     4981 actgataatg atttaaaaca ggaaaccaga taaatttcca ctggtctgtc aaaatatatt
     5041 gactagaatc ttttcctaaa gtatgttcac catgaaattc tgttcgccac ccctcgtact
     5101 gtccaaataa taaattctta acactccgtc catctagttc atctgtagta gttcctcctg
     5161 ccaaatccac gagtgaagga aaaatatctt gaattttcac taattgcttg attgttcccc
     5221 tattaccagc tatcaatcca gccggatcgt aaataaacga aggaatgtgg atacttccct
     5281 gataaggata tccctttcta aacagataat gttcaccaag ctgatctcca tgatccgaaa
     5341 caaaccagat aatcgtatct ttatcatgac gaaattcttt tagggcagtc aaaaagcgac
     5401 taatttgatg gtctatatga gtaatcaatc caaaataagc agcaaccatt cttctttgat
     5461 catcttcctt taatttccct cttaaagcat aaatagacgg aatttgcttt tctaatactt
     5521 cccaattccc gatatgcaaa tcgagaaatt gaggcaagcg ttccatatac atatcaaaat
     5581 agtattttgg gggatttaat ggagcatgtg gtttttcaaa agacattttg agaaaaaaag
     5641 gaaccgttgg atctcttctt tgtaaaaatg aaatggactc actcacaacc cagtttgttg
     5701 gatgtaactt ctcatcttta tcccaaggtc tagcttccca agaattacaa tccattccgt
     5761 catcaatcaa atcaacatca taaccaactt taccctttaa aaaggctaga tagtcactag
     5821 cataatcaaa ttgacttcca taagccttat catactttct atcaacatgt agatacccat
     5881 cgtgaagtaa gacatgatca aacccaagtc tctgtctgga aggaaaaaca tgcatcttac
     5941 caatacactc tgtttgataa cccatatctt taaagacttt tggaagagta ttagtaaaat
     6001 tccaaggcac ctcatcttga taaccaactc gtccactttt atcttggtct aagccagtca
     6061 ataaagctgc cctagcagga acgcaagaag gaactggaga ataggcattt tcaaaattat
     6121 aacctacact agccatcata tctaatgttg gagtgctaac tagcttatcc ttactattca
     6181 aggataaggc gtctgctctc atttgatcta caacaatcaa aataatattt ggctgttttg
     6241 tctgaaccat aaaatctcct ttctaatatg gcaaaagagg cacaagaaga tatctacctt
     6301 tactgcaccc ctttctatat caatctctct atataaaaca ataacattct tgttatgttt
     6361 tatagaaaaa tgaactaaaa tatgactaaa tcgattagga aattcaaatc attttctagt
     6421 actattttag aagttacagt gtactattcc aacttcaata aactataaac ctttgtctaa
     6481 taacaatttt agtggagata agaaatccta cacctaactc aatcttacac gtaatctatt
     6541 tctattttat cacaaaaaac gcaagtaaga ccattaactc aattcagttt tatctgccat
     6601 tttcacaaat gggaaataag tcaagacact aataatcaaa caaacaactg ataagatgat
     6661 ggcacgccaa tcaaatgctg tagagaagaa accatataaa attggaggca ttacccaagt
     6721 aacattttgt gtaacaggtg aaacaagacc ccagcttgtt gcccagtaag ctaccgttgc
     6781 catgaaaacc gggctaagta caaatggtat aaatagcaaa ggattcaaga caactggtaa
     6841 accataattt accggctcac caatattaaa cagaactggt gctagaccaa gtttagcaac
     6901 ttttcgataa tgactgtttc ttgaaaaaat taaaatagca agtaccaatc ctaatcctcc
     6961 aaaccagaca aacgccccaa aagacccact tgtccatata taaggaatcg gttcaccttt
     7021 ttggaaagca tccagattcg ctaacatagc aactccaaac agcccttcca tgatgggagc
     7081 caatacattt cctccatgga gaccaaaaaa ccagaataac ttatttaaaa agatcatcag
     7141 aataactgca aagaaacttt gagacaaacc tagtaatggc gtttgtaaca ccttgtaaac
     7201 ccaatcaatc aataagtaat tgctaagtaa atggaaaaca taagtcaaga tggctactat
     7261 atacatcgcc ataaatcctg gaatgataga agtgaacggc ttagcaatcg cagggggaac
     7321 tgaatctggt aacttgatta cccagttctt tttcattact ttacagaaaa taatagaggc
     7381 taaaaatcca atcatcatgg ctgtaaagta gcctctggca ttaatatggt ttcctggaat
     7441 cacattccca atagttacca tcagattttt accatcaaat gctagattat caattccttg
     7501 taagatttga tctaatttca catctcctac atttgccaaa gggaaactct ttgtaactgt
     7561 acttccaatc gaaatgacaa acgaagcaag cgataccaaa ccagcagaaa ctgtatcaac
     7621 cttataaatc ttagcgatat tcactcccaa gcaatagatg aacaataagg aaacaattgg
     7681 tatacttccc ttgaatacca aattattgat gtcaacaagc cactgaaagg ttttcgtaat
     7741 actttctagg tgaaattgtt gtggtaaatc cactagaaaa gcatttaata acaaagcaat
     7801 ggaacctgtc ataataacag gcatagtccc cacaaatgaa tcacgtaaag caactaaaaa
     7861 cttctgattc ccaactttca ttgcaattgg agaaagtttt tcttgcattt tatccaacat
     7921 tgtattcata gcaaattcct aatttttttc aaatcgttcg tatacttcta ccacttcttt
     7981 cgccaagtca acaaaggtca gactcgtcat taaatgatct tgcgcgtgta ccatcaagag
     8041 gctaattgat gtttcttccc cctgtgcctc tcttgtcaac atttctgttt gagccttatg
     8101 cgcctgtaat aaggcagcat tcgcatcagc taatcttcga ttggctttag agaaatcccc
     8161 tttttttgct gcctgaatag cctccatagc attacttttg gcttccccac catacataat
     8221 tagccccatt acagattcta aattactttc atccataaca ttctcctcaa tcttagtcta
     8281 ataaactttc agctaaatct aagactttag aaccattcat cattccataa tctgtcatcg
     8341 gaataaccgc cacaggaatc tgtctatctt ttagtttttc ttgaaagtcc cctagtaaat
     8401 agcgaacttg aggacctaaa agcaacacat ttacttcttt tgttgctaca atttcttctg
     8461 cttcaggagc tggaactgca aaaatttctg catccaaccc cttatcttct gctgcctttt
     8521 gcatctttgt cactagcaga cttgtactca tacctgctgc acatgctaac ataattgtta
     8581 ctttagccat agcttactcc tttatcacct atttactgac ctagccaagc gagatactgt
     8641 atgtctcact cctctaattg ccttgctcaa tgcataaata ttatcgactg ttgccagtcc
     8701 cccatatcct gcgtcaccta tatgttgaat atcaactcca caaattttat ttctaagtgc
     8761 aatttcctta atagtatctg tatcagatgt ttcttggcta gtaccaatag cactcaatac
     8821 aagaccaccc ttactatgaa cgagatcaac gacttcacgc aactcttggt catgaaaggc
     8881 tggaacggtt ccaactgctg gaacaagtat cacatccgca cctgcttcca acaattgctc
     8941 tgcgacagaa agctctgcca caggctcatt cactcctgcc ccgtgcatct tacctgcaat
     9001 aatcaaacca gaaaagtttt ccttagcagt ttgaacagcc ttaatgattt ctcgattgct
     9061 aactcctgtt ccaggatttc cagtcaaaca gacaaagtca aaacctaact cctctattcg
     9121 cttcaatgtt tcaacactag caacacgacc tgcaacaatt tcctgtgttt cctctagcat
     9181 ctttgcagat gggtcaatcg gttccaaatt tacaccaatt gggcaagcaa cgagctggtg
     9241 taagcgatga ataacatcat cacctgaact atccaaagca taaattttag gctcaaaaac
     9301 atcaacacaa ttcaataaaa tcatatcagc tccaaaagct ctagcaattt cagaattagt
     9361 tatatcccca acaaatgtct cacgagtgac tacattttca gatagaacaa ctctaccttc
     9421 acttgctaaa atactttgtt ttaattcttc agcattcatc tgtaatatct cagatggatt
     9481 tgcactaatt aaacgtttca ttctcaatcc tccaataact taaaccgttt ttcaatagct
     9541 attacaaatg gtaaataaag taagacatcc aaaacaatca atacaatttg taataatgaa
     9601 ccagaaatac ttcctgtagc aagtaaacca cttataacag gtggcatagt ccaacctgga
     9661 tctgtataag ttagcggaac caagcctgat gccattgctc cccacgctac tagtaagtta
     9721 aacattggag ctaagataaa tggaactagt aacaaaatgt tcaaaacaat aggaacacca
     9781 aacattgctg gttcatttat attaaataat ccaggtataa cagttatagg tgccaaagtt
     9841 tttagttgtt tactagcttt cttcttatgt gctaaatatc ctaacgcaag aactaaacct
     9901 atggttgcac caccgccacc tatgaataca aaattatcca taaatacgct agtaaaaata
     9961 tttggaagag tttctccagt ttgataagct actttatttg catctagatt agctaaccat
    10021 aacggtttca taactgcatt aacaacattt cctccgtgta atcctacaaa ccaaaaacta
    10081 ctattaagga aaattaagat aagaagacca ataacattat ttcctaaaag tccaagtgga
    10141 cctcccaaag ctacttgagc aatttcatga agattaggta aacttaattt atctaaagtt
    10201 gcataaacaa tcaaccaacc aacaatagtc actgcaccag gaataatggc actaaagctt
    10261 ttagatactg ctggtggaac accatccggc atttttatct gtatattatg atttataaac
    10321 cattggtaga tatagccatt aatcaatcct aaaatcatag caacaaataa accttttgat
    10381 gccatgaaag cggtaggcat tcctgctcca gcctctcctc taatgaaagg cgtaactgta
    10441 ataaaagatg ataatgacac aataccagca ggaataccat caactttgta ttgtctagcc
    10501 ataaagtaag cgataccaaa actagctaca agaccaagta atccaaaact actatcaaca
    10561 cccttccata aatagtcagc aacaccaata tcacccagat atttttccca tcctggaata
    10621 ggaaaacttg caataaccat tagtaatgaa cctatcaaca ataaaggtat agttagagta
    10681 ataccgtctc gaatagaaac caacgcttta ttattaccca atctagccgc tactggaagt
    10741 aacttttctt gtaataattt ttccataacc ttttcctctt aaatatattt tattatcaaa
    10801 agttatcaat tatctttatt ttttgacgtc aagttgttat ttgattatct tttgttattt
    10861 atattttaca actat
//
LOCUS       DAVMCG010000054        10806 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVMCG010000054 DAVMCG010000000
VERSION     DAVMCG010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.055"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..737
                     /locus_tag="VYP66_001846"
                     /pseudo
     CDS             1..737
                     /locus_tag="VYP66_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            637..1083
                     /locus_tag="VYP66_001847"
     CDS             637..1083
                     /locus_tag="VYP66_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1851345.1"
                     /translation="MRKHGLISKSTSKRYYQVAIPFTRLFCPALVSIDYINCLSETTD
                     KNWHKSDRIFVTNIGKPVHSSILSKSLQRANERLKKPIPKHLPPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTQVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1221..2525)
                     /gene="eno"
                     /locus_tag="VYP66_001848"
     CDS             complement(1221..2525)
                     /gene="eno"
                     /locus_tag="VYP66_001848"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1851346.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2689..3135
                     /locus_tag="VYP66_001849"
     CDS             2689..3135
                     /locus_tag="VYP66_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1851347.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(3132..4247)
                     /locus_tag="VYP66_001850"
     CDS             complement(3132..4247)
                     /locus_tag="VYP66_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1851348.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4256..4585)
                     /locus_tag="VYP66_001851"
     CDS             complement(4256..4585)
                     /locus_tag="VYP66_001851"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEV1851349.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(4530..4901)
                     /locus_tag="VYP66_001852"
     CDS             complement(4530..4901)
                     /locus_tag="VYP66_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEV1851350.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4960..6393)
                     /gene="glgA"
                     /locus_tag="VYP66_001853"
     CDS             complement(4960..6393)
                     /gene="glgA"
                     /locus_tag="VYP66_001853"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1851351.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6390..7529)
                     /gene="glgD"
                     /locus_tag="VYP66_001854"
     CDS             complement(6390..7529)
                     /gene="glgD"
                     /locus_tag="VYP66_001854"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1851352.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAEMFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GKGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7519..8661)
                     /locus_tag="VYP66_001855"
     CDS             complement(7519..8661)
                     /locus_tag="VYP66_001855"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1851353.1"
                     /translation="MKNKMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGAVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8651..10579)
                     /gene="glgB"
                     /locus_tag="VYP66_001856"
     CDS             complement(8651..10579)
                     /gene="glgB"
                     /locus_tag="VYP66_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1851354.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFVERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3311 a         2364 c         1916 g         3215 t
ORIGIN      
        1 ctggttaaag ctaaaagaga aaacaggaga gctaaaccac caagtaaaag gaacaaaatc
       61 aagaaaagtt gatagagata gacttaaaaa ctatcttact gacaatcccg acgcttattt
      121 gactgaaata gcttctgaat ttggctgtca tccaactacc atccactatg cgctcaaagc
      181 tatgggctac actcgaaaaa aagaaccaca cctactatga acaagagcca gaaaaagtag
      241 ccttatttct taagaatttt aatagtttaa agcacctagc acctgtttag attgatgaaa
      301 caggattcga tacttatttt tatcgagaat atggtcgctc attaaaaggt cagttaataa
      361 gaggtaaagt atctggaaga agatatcaga ggatttcttt ggttgcaggt ctaacaaatg
      421 gtgagttaat cgttccaatg acttacgaag agacgatgac gagcgacttt tttgaagctt
      481 ggtttcagaa gtttctctta ccaacattaa ccacaccatc ggttattatt atggataatg
      541 caagattcca tagaatgggt aagttagaac ttttatgcga ggagtttggt cataaacttt
      601 tacctcttcc tccctactcg cctgagtaca atcctattga gaaaacatgg gctcatatca
      661 aaaagcacct caaaaaggta ttaccaagtt gcaatacctt ttacgaggct cttttgtcct
      721 gctcttgttt caattgacta tataaattgt ctaagcgaaa caaccgataa gaattggcac
      781 aaaagcgacc gtatttttgt taccaatata ggaaaaccag ttcatagttc tatcttgagc
      841 aagtctctcc agcgagcaaa cgaacgcctt aaaaaaccaa ttcccaaaca tctgccccct
      901 cacatcttca gacacaccac tattagcatc ttatcagaaa ataaaattcc tttaaaaaca
      961 atcacggaca gggttggtca ttccgactct gaagtcacta cttccatcta cacccaggtc
     1021 acaaagaata tgaaagatga agcaatcaat gtactggata aagttatgaa aaagattttt
     1081 taaaaagttt tgtccctttt ttgtcctcta aatacaaaaa tagcccttcg gataaaatcc
     1141 gaggggctag aaacgttgtt aaatcaacgg ccgaactttt gaatttcatg gttcgggata
     1201 aaatagttca ctgaactatt ttatttttta aggttgtaga atgatttcaa tccacgatat
     1261 tcagctactt caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg
     1321 tctgtacgtg aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca
     1381 gcgattgttg aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct
     1441 tctttagcca tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg
     1501 ataaggattg agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt
     1561 acgaagaagt catcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc
     1621 caaccatccc agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta
     1681 accaattctt caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct
     1741 tcaaatttag tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag
     1801 tcaaatccga taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg
     1861 atagtttcaa caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct
     1921 acggcagttt ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca
     1981 ccgtaacgaa gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg
     2041 aaagcgattg gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga
     2101 agaactttag tgttgaatcc accaagatag ctgtaaagtg ggatttcaag gtagtcagca
     2161 gcagcacgag ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg
     2221 ttaggagtac cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg
     2281 tagccaatga tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca
     2341 agaccaccgt aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta
     2401 gaagctcctg atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact
     2461 tcaagtgttg ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt
     2521 gacatttttt actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc
     2581 ctcctttttc aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat
     2641 cgctttcttt tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta
     2701 tcaaaacaat tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga
     2761 cgctatcttg gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat
     2821 agccctcagt tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag
     2881 ccactatttg tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa
     2941 gaagcaaaag aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct
     3001 tttggcctgg ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt
     3061 gcttttccaa aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag
     3121 aaatggttta gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc
     3181 tccagataga gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata
     3241 gaaaagacag cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg
     3301 caaatagcaa taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc
     3361 ccagcaaagc tttgactgtc aagtcttcct tctccaacaa caaccaagtc agcatctgaa
     3421 actttcttat caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc
     3481 tgagcaaagg cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct
     3541 aatgttgcag gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac
     3601 atagtcggat gtagaccttt ttgattgcca aaagtgtaag tcgcaccttg ataaccacat
     3661 aagggactca cgacatctgc taaaatatga atttgaacac cttcaggaat tttatagcga
     3721 ttttctgttg aaacagaagc taagtttaat aaggattgac cggaagcagg caagacattt
     3781 ccatccctat cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta
     3841 ctggccgtgc caccaacacc gatataaata tctttaatcc ctttagaaat gagatggaga
     3901 atcaactctc caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt
     3961 tttccaagac caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag
     4021 cgcatggctt ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca
     4081 agagaatgtc ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga
     4141 cattctacat ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga
     4201 gctgtcaagc tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt
     4261 ctaaacagtc aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta
     4321 tttctttttt gagcacttct ttggcacaaa aggcgattcc taactccgcc gacttcaaca
     4381 ttaatagatt attgacccca tcaccgattg ccaccgttct ttctttagaa agttttagtt
     4441 tctttctcca tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta
     4501 attttcctgt taaaagacct tctttgactt caagctggtt ggcagtgaaa taggcaatac
     4561 caagggattt tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact
     4621 aggatgccat tcttttggag aatagagatg aactctggga catttagcga tagatgaatt
     4681 gagttgaaga cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt
     4741 cttaaactgc tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt
     4801 tccgcctcat gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt
     4861 ccatctacat ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca
     4921 gcctaaaaat cgtatgaagt catcatacga ttttatctat taattaacta aactatggta
     4981 caagtcaagg tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt
     5041 ttgtaggttt ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt
     5101 ccaatttaac caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat
     5161 tggattgaaa gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt
     5221 tccataacgc atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag
     5281 gaagaggtca caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt
     5341 tgatagcttg tctgggtaaa tctgagcaaa ccatgagaaa gctccttcaa aggctggatc
     5401 gccagttccc aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac
     5461 caccacatca aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc
     5521 tgctctaaca ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga
     5581 caaatcttcc tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc
     5641 agcatcaatc ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc
     5701 caaattacat ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga
     5761 aacacggttc gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag
     5821 ggtgccatca gcgtaacgtt caaggccaac tccaaacaaa tcacccaaca ttccttctga
     5881 aaattgtcct tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc
     5941 ttgaatccaa cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg
     6001 aacatggaga agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg
     6061 gaaaaaggca aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata
     6121 atattgattg tcaataaagt agaaggttac accatttaat actgttttct taattccaca
     6181 atactgtctg cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc
     6241 aaatttagcc tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt
     6301 taccagtgat tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaagg
     6361 tgcaccctct gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca
     6421 cctttcttaa ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact
     6481 tcaacccctt tgtccaagat agcatattcg acctgagccc cttttccaat aacaacacga
     6541 gggaagagca ggctatcttt aaccaagcta tccttatgga catgaatatt acgtgataga
     6601 acagaattag ctacttgacc ttcaataata ctaccagagg caaactgaga agtgcttacc
     6661 ttagatgtat tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg
     6721 tttggtgaga aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa
     6781 taagatttaa cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc
     6841 tcttttacag ccaaatcccg taaaacatag cgcaatttct ttggatgttc ttttttagct
     6901 tcttcttcca agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata
     6961 ttgaacattt cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt
     7021 tcatctacat ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa
     7081 actacagtga taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg
     7141 ttaataagaa catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa
     7201 gtaagaagct gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa
     7261 attcctagat agtaatgact aagaagggtt gataagcccc actcgcgtcc tgaacgaata
     7321 tggtcaaata ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct
     7381 gcattagcaa ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa
     7441 cttgctactg gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct
     7501 aaaatggcag aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc
     7561 tacaacttgt acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc
     7621 accaataatg gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac
     7681 tgaatcaagg acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt
     7741 aacagctcca tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc
     7801 cccgaggaag tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg
     7861 actatccaag gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat
     7921 agtaccaaca tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc
     7981 aaggtaattt ggaatgacat ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc
     8041 agcgactaac atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt
     8101 tgtagattta ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt
     8161 gttcatgata ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa
     8221 gctggcatta ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg
     8281 gtccccagac aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg
     8341 gtaaatagcg tgactagttc cctcaaacca acgatttcct tcacttgcag aataaggttg
     8401 aagaatagag acgcctgaat taataccgtc tagtccccag cttgaaccat tcccaatatg
     8461 gttgttgaga gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt
     8521 ggcacagttt gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg
     8581 ttttgcgatg ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa
     8641 agctaacatt ttatttttca ttttctactc ctttttggtt tttatttgtg acggttttag
     8701 tagatttcaa gcgacgtttg attttccata cacttgctcc catagccggt agagtaaagg
     8761 ttaaggtctg ctcataatct ttccataggc cttcttgcgt ttgaacagtt tgattatgtt
     8821 ctttccaaac gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg
     8881 caacgggtag tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga
     8941 ctaacatttc tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat
     9001 ccgcatcaat gatttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat
     9061 ctttgtaaaa ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt
     9121 ctaggttaga ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc
     9181 tacccatgaa gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca
     9241 agcctgcgaa ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat
     9301 gaaccacttc atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc
     9361 tgaaagtcac caggttaaag tcatatttac gataaatcgg atcttcttcg tagaaacgga
     9421 ggatatcatt catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt
     9481 tcattcccgt aatcttggtc gcagacgaac tttcttctgc aatcatcatc acatctggat
     9541 attctaactt aataacttca ttcaagcgtt gaagaaaata ataaccttca tagttaagat
     9601 ttccgccatc tttattaggt gtccatggag cattatcata gtccaaatag agcatgttgc
     9661 taacagcatc cacacgaata ccatccaaat gatagacatc aatccaatgc ttaatgcaag
     9721 aaattaagaa ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat
     9781 ggttatgagc cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta
     9841 aggcatcatc gttgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat
     9901 gggtatgaca ctcctcgaca aaatcttgaa actcctctgg tctgccataa gcatgctcta
     9961 aagcgaagta acccataagc tgataccccc aactcaagcc caaaggatgg gacatcaagg
    10021 gcataaactc aatatgagta tagttcattt caacgagata aggaatgagt tcatccttga
    10081 gctgggcaaa actataagga ctgccatcag gatttctctt ccaagagcca gcatgaacct
    10141 cgtaaatatt gacaggacgt tcaacaaagc cccaacgttt tcttcgtgcc agccaaagtc
    10201 catccctcca tttcttatca ggaagctctg ttacgattgc ccctgttcct ggacgagcct
    10261 catacctgac agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat
    10321 gatatttgta aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaagt
    10381 catttcttac cattggaatc tgattttcaa tccagttggt aaaatcacca accaagtgaa
    10441 cagcctgagc attaggtgcc caaacacgga aggtatagcc atgctctcca tttagttctt
    10501 ccctatgtgc tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta
    10561 atgcttctct attatccata tactcccctt ctcctgtaag cgttttctat gtttttatta
    10621 tactaccttt ttagagaaga ttcaagtaaa ttactatact tctttaatta ttttgaaaat
    10681 ctacaacaag ttcacttact cgttcaattg taaatcaata ttttttcaaa aaattgcgaa
    10741 aacgcctttc tttttctact atagtgaaat gaaataaaac atgcgcaaat cgatcaggac
    10801 agtcaa
//
LOCUS       DAVMCG010000055        10761 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVMCG010000055 DAVMCG010000000
VERSION     DAVMCG010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.056"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..185
                     /locus_tag="VYP66_001857"
     CDS             <1..185
                     /locus_tag="VYP66_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1851355.1"
                     /translation="EYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFATSSSG
                     VTLITGKNGTGKSTLL"
     gene            complement(551..1861)
                     /locus_tag="VYP66_001858"
     CDS             complement(551..1861)
                     /locus_tag="VYP66_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1851356.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            2098..2970
                     /locus_tag="VYP66_001859"
     CDS             2098..2970
                     /locus_tag="VYP66_001859"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1851357.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            3101..3930
                     /locus_tag="VYP66_001860"
                     /pseudo
     CDS             3101..3930
                     /locus_tag="VYP66_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3991..4953
                     /locus_tag="VYP66_001861"
     CDS             3991..4953
                     /locus_tag="VYP66_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1851358.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            5130..6137
                     /gene="gap"
                     /locus_tag="VYP66_001862"
     CDS             5130..6137
                     /gene="gap"
                     /locus_tag="VYP66_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1851359.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHNVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(6205..7041)
                     /locus_tag="VYP66_001863"
     CDS             complement(6205..7041)
                     /locus_tag="VYP66_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1851360.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            7167..9362
                     /locus_tag="VYP66_001864"
     CDS             7167..9362
                     /locus_tag="VYP66_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1851361.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTSGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            9415..9567
                     /gene="rpmG"
                     /locus_tag="VYP66_001865"
     CDS             9415..9567
                     /gene="rpmG"
                     /locus_tag="VYP66_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1851362.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            9577..9753
                     /gene="secE"
                     /locus_tag="VYP66_001866"
     CDS             9577..9753
                     /gene="secE"
                     /locus_tag="VYP66_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1851363.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            9808..10344
                     /gene="nusG"
                     /locus_tag="VYP66_001867"
     CDS             9808..10344
                     /gene="nusG"
                     /locus_tag="VYP66_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1851364.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            10466..>10761
                     /locus_tag="VYP66_001868"
     CDS             10466..>10761
                     /locus_tag="VYP66_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1851365.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEG"
BASE COUNT         3382 a         1832 c         2353 g         3194 t
ORIGIN      
        1 aagagtatga aaacagaact gtttcttttg ctattagttc aaaaggagaa aaaatgaaag
       61 tagaaaatat ttcgtatagg gtggatcatc gtatattgtt tgataatatt tcttttgcta
      121 cttcgagttc aggcgtgaca ttaattactg gtaaaaatgg tacaggaaag tcaactttac
      181 tatagtagat tgaaactaga atagtacaca tctacttcta aaatattgtt agaaatcgat
      241 ttgactatcc tgatctattt gtcctgttct tatttcattt cactatatct caaattgagt
      301 atgacgaagt gcgctcccat gtcctgggaa cgcactttct tcatattttt catattcttg
      361 aatccatcga taaagactat tgggatgaat ttttaaagtt gaactaatca tttttacagg
      421 atgagattta cagcagagag tttgaaggct ttatcaaagg tttttcttgg cataatgact
      481 tttcctcgtt tccacttaat tttgtgtcta ctttattata ccaagtccac ccttaagtta
      541 gataataaat ctaacttaag gaagctagaa ggatgagaat ccaggtggtc aagagtccca
      601 aacttaagct gatggggaca cccagaataa tttgcttttt gaaggcaagg ccacgttcct
      661 ctatattggg aagtgagagt tgaatgagag aaccagctga tgaaaagggt gagatattag
      721 tagatagagc gccaataacg gtggctgttg tgagtaagtg aatatcaatc tgaggatttt
      781 gagcactgat gatagcaatg atgggaaaga gggctggagc tacaacggat agggtggaac
      841 taaagagtga catcactccg gctatcacac aaaagaacag aggtaaccag aaatgaggaa
      901 tggttgttgt catgaggtgc cctatcagtg tgactaaacc tgacttgacc gctagagaca
      961 ttagtaagct catgccgcag agcatgataa ttgtagccca gggaacctta gctaaaatgg
     1021 cttcttgctt ccctaatttg agccttaagg cgaggcagac catgagtatt gagacaaagc
     1081 caatatcaaa tgttttttga taagtagcta tccaggcgat gtttgggaaa atgagatgca
     1141 acaagggaaa aagccaaacc aaaaccatgc tgctgatcat gagcaaggtg gtttgtcttt
     1201 gaaccttgct gaggagtggt ggttggtcaa tagtcaagga tgagtttgtt cttcccttac
     1261 tatagtgact gtaacaggat aataaaagca agacgatgag tgggtagata atgctgacga
     1321 taaagatatg attgccaagt gaaaaagctt gctcttccca tcccatttgc ttaaacaggc
     1381 cttgaaagac aatgcctgag ctactggtta tcaaattagc ccctcctgaa gctccccaat
     1441 tgacggcttg agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta
     1501 gaggacagca aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg
     1561 ccatcaggta taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt
     1621 gttgagccaa aacatcaaga gtaccgttag ttgttgcaac gttataaaag agagagacgc
     1681 taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag aagttctttg gggcttaatc
     1741 ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt
     1801 tggtgcggta accaattcca atggctagag caatggcgct aatcattatt aaatgaatca
     1861 ttgaattgtc ctttcagtta gaatatggaa atagattggc aattttggcg ctcaaaagac
     1921 cacctgtttc ctattggtac ttgactatta tacacaaaaa aaatacaatt gtcttgacaa
     1981 ttgtattgac acttgttaga attaaaaatg aggtattcag gcttgtgatt tcctatggaa
     2041 gttaatagta attgcctcta gtgcttacaa gtgatattaa aaatagagga cttagtgatg
     2101 tcaatcattt caactgattt aacccctttt caaatagatg atacattgaa agcagccttg
     2161 cgagaagatg ttcattccga agattacagt accaatgcca tttttgatca tcatggccaa
     2221 gccaaggtgt cgctttttgc caaggaagct ggtgttttag cgggactaac cgtttttcaa
     2281 agggttttta ccctatttga tgccgaggtg accttccaga atcctcatca atttaaggat
     2341 ggggatcgtt tgactagtgg cgatttggtt ttagaaatca taggctcggt gagaagtctc
     2401 ttaacatgtg aacgcgttgc cttgaatttt ttacaacatt tatcagggat tgcttcgatg
     2461 acagctgctt atgtagaagc cttaggcgat gattgcatta aggtatttga tactcgaaaa
     2521 actactccta atttacgtct ttttgagaaa tatgccgtga gagttggcgg tggctataat
     2581 catcgcttta atttatcaga tgctatcatg ctaaaagaca atcacattgc ggcagtaggt
     2641 agtgttcaaa aggcaattgc tcaagcgcgt gcctatgccc cttttgtgaa aatggtcgag
     2701 gtggaagtgg aaagccttgc tgctgccgaa gaagctgcgg cggcgggtgc tgatattatc
     2761 atgttggata atatgtcatt ggaacagatt gaacaggcta ttaccctaat tgcaggacgt
     2821 tctcggattg aatgttctgg aaatattgat atgaccacta ttagccgttt tcgtggttta
     2881 gcgattgatt acgtctccag tggtagttta acccatagtg ctaagagtct tgatttttcc
     2941 atgaaggggt taacctacct tgatgtctaa gttgtaaaat aaactaactt tttaaaggat
     3001 gtttttcctc tagaacgagt tttatgtcag atagtttaaa cgcctcttca aatatagtaa
     3061 aatgaaccaa aaatagtaca caatgtggta taatcttttt atggcatatt caatagattt
     3121 tcgtaaaaaa gttctctctt attgtgagca aacaggtagt gtaacagaag cataacacgt
     3181 tttccaaatc tcacgtaata ccatttatgg ctggttaaag ctaaaagaga aaacaggaga
     3241 gctaaaccac caagtaaaag gaacaaaacc aagaaaagtt gatagagata gacttaaaaa
     3301 ctatcttact gacaatccag atgcttattt gattgaaata gcttctgaat ttggctgtca
     3361 tccaactacc atccactatg cgctcaaagc tatgggctac actcgaaaaa aaagaaccac
     3421 acctactatg aacaagagcc agaaaaagta gccttatttc ttaagaattt taatagttta
     3481 aagcacctag cacctgttta gattgatgaa acaggattcg atacttattt ttatcgagaa
     3541 tatggtcgct ctttaaaagg tcagttaaga agaagatatt agaggatttc tttggttgca
     3601 ggtctaacca atggtgagtt aatcgctcca atgacttacg aagagacgat gacgagcgac
     3661 ttttttgaag cttggtttca gaagtttttc ttaccaacat taaacacacc atcggttatt
     3721 attatggata atgtaagatt ccatagaatg gggaagctag aacttttatg cgaagagttt
     3781 gggcataaac ttttacctct tcctccctac tcgcctgagt acaatcctat tgagaaaaca
     3841 tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac cttttacgag
     3901 gctcttttgt cttgttcttg tttcaattga ctatatatca cggatacagt tgggaaagaa
     3961 gctattaatt atttggagag tccttttggg atgaacatgt caaatattac tatagatggg
     4021 caagaaatgg atctgagtca aacgatgcct tcttatgctc aagtagtgag tctttatgat
     4081 gatacaagta tctctgttag taataatgag acggacaaag tgttggctgg atccctctat
     4141 actgatacaa atgaacaggg attaacgatt ccaagcagtt tactaaaaaa ttggaatgaa
     4201 cagacaggaa aaaatttgac agctaatgat cttattggca aatcagtctc agccagcatt
     4261 gtagaaagtg ctgccgaaac tagtaagatt gctcaatttc aaacgaagat tgtacgtgta
     4321 atcaatgatg aagatgacat ggaggacagc aacagtttca tgctgtctca tcaaatggaa
     4381 acgattttga aagaggctgg atttacgaaa gctgtatctt attttatctt ggaactcaaa
     4441 gatccatcac agacaaaagt agtaacagaa gaattacaga aaaataagaa gtatactgtg
     4501 ctttctcaac agagagttct tgatattgtg attaccttta ttcgtgttat tcagggatta
     4561 ttgattgtgc tttcatcaca agctattgtg gtagcagcgg ttatgattgg tatcattatt
     4621 tacatcaata tcatgcaacg ttccaaggaa ataggtgtca tgaaagcagt tggttatcag
     4681 aatcgtgatg tcaaaggaat ttttatttac gaggctatct ggattgtagg catcgccttg
     4741 ctgctggcat ttttggttgc acaaggggtg ggaagtttgg cgaatgcgat tgtaagtcac
     4801 ttttacccat ccatcactaa ggtttttgaa ttaaatcttt tatctgtttt aggaactcta
     4861 gttttcgctc tattacttgg ttatgtctca gcctacttcc cggcgcgtaa gattagtaaa
     4921 atggatcctg tagaatcgtt acgctatgaa tagtaaggga ttccttgatt tacagtctta
     4981 aaaagaaact aacatagaaa aacaatggcc atacttgcaa ttcaactcaa atagttgtat
     5041 aataggtttg ttgaaaggtg atttgtagtg attcaagtta ctcttttcac aataaaaatt
     5101 tcatgatttt cataaggagg aaatcactaa tggtagttaa agttggtatt aacggtttcg
     5161 gacgtatcgg tcgtcttgct ttccgtcgta tccaaaacgt agaaggtgtt gaagttacac
     5221 gcatcaacga ccttacagat ccagttatgc ttgcacactt gttgaaatac gacacaactc
     5281 aaggtcgttt cgacggtact gttgaagtta aagaaggtgg atttgaagtt aacggtaaat
     5341 tcatcaaagt ttctgctgaa cgtgatccag aacaaatcga ctgggctact gacggtgtag
     5401 aaatcgttct tgaagctact ggtttctttg ctaagaaaga agcagctgaa aaacacctta
     5461 aaggtggagc taaaaaagtt gttatcactg ctcctggtgg aaacgacgtt aaaacagttg
     5521 tattcaacac taaccacaac gttcttgacg gtactgaaac agttatctca ggtgcttcat
     5581 gtactacaaa ctgcttggct ccaatggcta aagctcttca agacaacttt ggtgttgttg
     5641 aaggattgat gactactatc cacgcttaca ctggtgacca aatgatcctt gacggaccac
     5701 accgtggtgg tgaccttcgc cgtgctcgcg ctggtgctgc aaacatcgtt cctaactcaa
     5761 ctggtgctgc aaaagctatc ggtcttgtaa ttccagaatt gaatggtaaa cttgacggat
     5821 ctgcacaacg cgttccaact ccaactggat cagttactga attggtagca gttcttgaaa
     5881 agaacgttac tgttgatgaa gtgaacgcag ctatgaaagc agcttcaaac gaatcatacg
     5941 gttacacaga agatccaatc gtatcttcag atatcgtagg tatgtcttac ggttcattgt
     6001 ttgacgcaac tcaaactaaa gttcttgacg ttgacggtaa acaattggtt aaagttgtat
     6061 catggtacga caacgaaatg tcatacactg cacaacttgt tcgtactctt gaatacttcg
     6121 caaaaattgc taaataattc ttgagttgat agaaagcaag gctttgtggt cttgcttttt
     6181 tatatggaaa aatggatgac acgatcatcc attctttttt aattcttttt caaatgtatt
     6241 tgaaagggta gtgaaagtta gcttctctaa agtaagtggg tgggtaaagg aaagtcggaa
     6301 ggcatgaagc ataagccggc ttgtctttga tttactatta tagagagggt ctcccaggat
     6361 aggaagatta tgatgcgaaa ggtgcacacg aatctgatgg gttcgccctg tctttagctt
     6421 gcaatgagcc aaggaagtct tgtttgagaa ttgctttaat ctgcttacat gcgtttcagc
     6481 atattgccca ttttttgcat caactattct ttttctacga tcatggcgat cacgtccaat
     6541 tttgtctctg aaaacaagtt cttttctgtt gatatttcca tcaactagag cccaatattc
     6601 tctagaaatc tcttttttct ccaataagcg attgagaatg ggcaggataa aaggattttt
     6661 ggcaaagaga actaagccac tggtttccat gtccagacga tgaacgacat agcaggtttg
     6721 gccaacatag gtactgacat ggttaagaag ggcaatttcg tttggttgat taccatgcgt
     6781 tttcatcccc tctggtttgt ttacaataat caagtgttga tcttgataaa cttcctgcac
     6841 taagtctggg ttgccccaag ggatcgtctt ttggggataa tcttcctcgt caaaagtcaa
     6901 ctggcaaaca tctccaggat ttacgatttc gttccagtgg acttcttctt gatttatcaa
     6961 aatatgtttc ttgattctca aaaaatgacg gatttttcta gggatgagga gttgttcctc
     7021 aagtaattgc tttaccgtca tttgaggtag agaggcgggt aatgtaaatg tgaattgcat
     7081 acagatattg taacaaaaaa agccctattt ggataggaaa tagctaaatt cttgtcttcc
     7141 tatgatgaag atgataaaat aaacgcatga aattagataa attatttgag aaatttcttt
     7201 ctctttttaa aaaagaaaca agtgaactag aggactctga ttctactatc ttacgtcgct
     7261 ctcgtagtga tcgaaaaaaa ttagcccaag taggtccgat tcgaaaattc tggcgtcgtt
     7321 atcatctaac aaagattatc cttatactag gtttgagtgc aggcttgcta gttggaatct
     7381 atttgtttgc tgtagccaag tcgaccaatg tcaatgattt gcaaaatgcc ttgaaaactc
     7441 ggactcttat ttttgaccgt gaagaaaaag aggctggtgc cttgtctggt caaaagggaa
     7501 cctatgttga gctgactgac atcagtaaaa acttgcagaa tgctgttatt gcgacagaag
     7561 accgttcttt ctataaaaat gacgggatta actatggccg tttcttcttg gctattgtca
     7621 ctgctggacg ttcaggtggt ggctctacca ttacccaaca gctggctaaa aacgcctatt
     7681 tatcgcagga tcaaactgtt gagagaaaag cgaaagaatt tttccttgcc ttagaattaa
     7741 gcaaaaaata tagtaaggag caaattctaa ccatgtacct taacaacgct tattttggaa
     7801 atggtgtgtg gggtgtagaa gatgcgagta agaaatactt tggagtttct gcatcagaag
     7861 tgagtctgga tcaagctgcg actctggcag ggatgctcaa ggggccggaa ctgtataatc
     7921 ccttgaattc tgtagaagat tctactaatc ggcgcgatac tgtcttgcag aatatggttg
     7981 cagcaggata tattgataaa aaccaagaaa ccgaagctgc tgaagttgat atgacttcgc
     8041 aattgcacga taagtatgaa ggaaaaatct cagattaccg ttacccctct tattttgatg
     8101 cggtggttaa tgaagctgtt tccaagtata atctaacaga ggaagagatt gtcaataatg
     8161 gctaccgcat ttacacagag ctggaccaaa actaccaagc aaatatgcag attgtttatg
     8221 aaaacacatc gctatttccg agggcagagg atggaacgtt tgctcaatca ggaagtgtag
     8281 ctctcgaacc gaaaacaggg ggagttcgtg gagttgtcgg tcaagttgct gacaatgata
     8341 aaactggatt ccggaatttc aactatgcaa cccaatcaaa gcgtagtcct ggttctacaa
     8401 ttaagccttt agttgtttat acaccagcag ttgaagcagg ctgggctttg aataagcagt
     8461 tggataacca taccatgcag tatgatagct ataaggttga taactatgca gggatcaaaa
     8521 caagtcgaga agttcctatg tatcaagcct tggcagaatc gcttaatcta cctgctgttg
     8581 ccactgttaa tgatttgggt gttgacaagg cttttgaggc aggcgaaaaa ttcggactca
     8641 acatggaaaa ggtcgaccgt gttcttggtg tcgccttggg aagcggtgtt gaaaccaacc
     8701 ctcttcaaat ggctcaagca tatgctgcct ttgcaaatga aggtttaatg cctgaagctc
     8761 attttattag tagaattgaa aatgctagtg gacaagttat tgcgagtcat aaaaattcac
     8821 aaaaacgggt gattgataag tctgtagctg acaagatgac cagtatgatg ttggggactt
     8881 tcaccaacgg taccggtatt agttcatcgc ctgcagacta tattatggca gggaaaactg
     8941 gaacaactga agcagttttt aatccggagt acacaagtga ccagtgggta attggttata
     9001 ctccggatgt agtgattagc cactggcttg gctttccgac cactgatgaa aaccactatc
     9061 tagctggctc tacttcaaac ggtgcagctc atgtctttag aaacattgcc aataccattt
     9121 taccttatac gtcaggaagt acctttacgg ttgaaaatgc ttataagcaa aatggaattg
     9181 caccagccaa tacaaaaaga caagtacaaa ccaatgataa tagccagaca gatgataatt
     9241 tgtctgatat tcgagggcgt gcgcaaagtc tagtagatga ggctagccgg gctatctcag
     9301 atgcgaagat taaggaaaag gctcaaacaa tatgggattc gatagtcaat ctatttcgct
     9361 aagatgcttg tcaaagccta gctttcttgt tataatggat aagatggagg cgttatggca
     9421 ctaaaaaaag caagcctagc ttgtgcggtt tgtggttcga gaaactattc aatcaagatc
     9481 agcggaaacc ccaagcctac acgactagaa gtaaataaat tttgtaagca ttgtggcaag
     9541 tacactacac atagagaaac gagataggag agagcgatgc gttttattgg agatattttt
     9601 agacttctta aagacacaac gtggccaact cgcaaggaaa gctggagaga ttttcgttct
     9661 atcatggaat acacagcttt ctttgtagta attatttaca tttttgacca gttgattgtt
     9721 tcaggtttga ttcgatttat taacattttt tagaagatta gtggagttaa ttacactaga
     9781 aatcttctat ttatgaaagg aaatatcatg gatagttttg ataaaggatg gtttgtttta
     9841 caaacttatt ctggttatga aaataaggtg aaagaaaatc tattacaacg tgcacaaacc
     9901 tacaatatgt tggataatat tctacgcgtt gaaattccaa cacaaacagt gcaagttgaa
     9961 aaaaatggaa agagaaaaga agtagaagaa aatcgctttc caggttatgt tcttgtagaa
    10021 atggtcatga cagatgaagc ttggtttgtt gttcgaaaca caccaaatgt tacaggattt
    10081 gtcggatcac acgggaacag atcaaaacca actccattat tggaacaaga aattcgtgac
    10141 attttggtat ctatgggaca aactgttcaa gaatttgatt tcgatgttga gattggtcaa
    10201 actgtacgta ttattgatgg tgcttttgca gactacactg gtaagattac agaaattgat
    10261 aataacaaag tgaaaatgat tatctctatg tttggtaatg acacagttgc agaagtaaac
    10321 ctaaaccaaa tcgcagaatt ataaccctga gagaggctgg agcctctctt ttttgtgcag
    10381 tttaggagct aaagggaaca gaatggagaa aatggaacaa atgtgttttc taatctgtta
    10441 gactgtatct agaaagggga aaattatgat taaagaattg tatgaagaag tccaagggac
    10501 tgtgtataag tgtagaaatg aatattacct tcatttatgg gaattgtcgg attgggacca
    10561 agaaggcatg ctctgcttac atgaattgat tagtagagaa gaaggactgg tagacgatat
    10621 tccacgttta aggaaatatt tcaaaaccaa gtttcgaaat cgaattttag actatatccg
    10681 taagcaggaa agtcagaagc gtagatacga taaagaaccc tatgaagaag tgggtgagat
    10741 cagtcatcgt ataagtgagg g
//
LOCUS       DAVMCG010000056        10655 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVMCG010000056 DAVMCG010000000
VERSION     DAVMCG010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.057"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(31..1455)
                     /locus_tag="VYP66_001869"
     CDS             complement(31..1455)
                     /locus_tag="VYP66_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1851366.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2000..4279)
                     /gene="pulA"
                     /locus_tag="VYP66_001870"
     CDS             complement(2000..4279)
                     /gene="pulA"
                     /locus_tag="VYP66_001870"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1851367.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4391..6349)
                     /gene="ligA"
                     /locus_tag="VYP66_001871"
     CDS             complement(4391..6349)
                     /gene="ligA"
                     /locus_tag="VYP66_001871"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1851368.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6442..7620)
                     /locus_tag="VYP66_001872"
     CDS             complement(6442..7620)
                     /locus_tag="VYP66_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1851369.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7700..8563)
                     /locus_tag="VYP66_001873"
     CDS             complement(7700..8563)
                     /locus_tag="VYP66_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1851370.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8566..10467)
                     /locus_tag="VYP66_001874"
     CDS             complement(8566..10467)
                     /locus_tag="VYP66_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1851371.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSHRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3190 a         2350 c         1913 g         3202 t
ORIGIN      
        1 accaggaaaa caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac
       61 atttgtcatc gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac
      121 accaaggaat gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc
      181 tacttcaagt ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga
      241 ttgaaggccg aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg
      301 aatgattggt aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac
      361 ttggtcaaaa agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg
      421 agcctctttt tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc
      481 aataacaggt gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc
      541 ttcctgaagc aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat
      601 ggccgtgcaa cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg
      661 ttccaaatct gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat
      721 aggacgcata ccagctaaac gaccaatacg ttctccaata ggggttgaac ctgtaaagtt
      781 gatgaagttg acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt
      841 aatggtgttg aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag
      901 tccagaaatg gaaccttgtg ttggtggctt aaacatgacc acattccctg caatcaaggc
      961 aggtgcaatt ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac
     1021 gataccaact ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc
     1081 accaccttcc attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa
     1141 gtctgctgta cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc
     1201 aaggatagta ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata
     1261 agccgcacgt tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg
     1321 catagcctca tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt
     1381 gattggtgaa taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt
     1441 ctgatatctt gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt
     1501 tcagaaaatc acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt
     1561 caaagtatac tcaataaaaa taaaaaaaat ccactacatc aaggcgagac taatgtggtt
     1621 tgaagaaatt ttcgaagagc gtgaatgagt atcatctata gtaaaataaa aaaactgaac
     1681 aatttggttg gggacagtca aaccaatttc tcacaatgtt ttagaaacaa gggtgtgcta
     1741 ttccaatttc aggctactat aactgtcata gattgctgaa acaaagtcta ggtaaaagtc
     1801 ttcataataa aaagaccccc tatcaagtgt tcaaaaactt tgataggagg tcttgttttg
     1861 tgaaaatatt tatcaaattt tctatacaag tgagctgtta gccaggttct ttctattctt
     1921 tcaatttcaa tgaatggatt ttttaccaat actcataact gggaatttgt ctgtgtaaaa
     1981 atagcgagat agatggtatt tataaaacac tcaagacagc tagactaata tcatttaaaa
     2041 cattatcttc ttttgagcga ctgttggtta ccaacatagc taaatttcct gcattttcaa
     2101 attgataggg ttctgattta gcattcacaa ctaccaagag gtgttctttg ccgtgaactt
     2161 catagataag gcagccgcta tgttcaatcg cagaatgcac aaagacatga tggtaaattt
     2221 catcatagct agagtaagaa aaggcaccag tttttgtctt caatcggatg acttgacgga
     2281 taaactcaat actgtcttga cgctcattaa tcaagttcca gttcacttgg ttcacactgt
     2341 caggagcatt atagctattc atcgcacgct ctctatcatc atgggtcaac tcaccatttt
     2401 caccagtcgc aaccagtttg gtacgaccaa attcttgacc gatttccata aaggccatcc
     2461 cctgcatgag cagattcatg gctgtggcag tttcgacctt gcgcatgatt tgctctgaac
     2521 tttggtctgg atgaagggtt gccaataaat cgtgaagatt gtaattgtca tgggcttcta
     2581 catagttaag cacctgattt ggatgtgtat aggttcctaa ttcacgactt cctaggattg
     2641 ctttagctag aattggctct gtcgcagcac cactgacaaa acctgacttg atagcaccat
     2701 aaacttctcc ccctttgaca gcatcgcgct gattgtcatt aaagaaacca atatttggca
     2761 tctggtaggc attgtccttc ttggccttat cataaggggt aagacctgtt cccatatccc
     2821 atccttctcc atagaggata atgttggagt cgatttcatc caagctttga cgaatcatct
     2881 gcatggtctt gacatcatga atccccatca agtcaaaacg gaagccgtca atattatatt
     2941 cctgcaccca gtatagaaga gaatcaatca tatacttgcg aaacatttcg tgttcactgg
     3001 ctgtttcatt tccaacaccc gttccattct ggaaggtacc atctggattc atacgataat
     3061 agtaatcagg gactgttgtt tggaatggtg catcaacaac tgagaaggta tggttataga
     3121 ctacatccat aatgactcca atacccgcat cgtgataagc ttgaaccatc accttcaaat
     3181 cacgaatgac ctgagctgga tcatctggat tagttgaaaa actagtttct ggcgcgttat
     3241 agttttgtgg atcataaccc cagttgtagg ttacatttcc atcctcatcg tattctttat
     3301 gacggtctgc aattggttgc aattgaacat aattgtagcc cagcttcttg atgtaatcaa
     3361 aagcagttga ctggccgtat tggttaactg ttccagcctg agcagcaccc aagaaagttc
     3421 ctcgaagatg ttcatctaca cccgatgtag gtgatttagt caaatcacga atgtgcattt
     3481 cacagataac tgccttacat ggattttcca agcgccaagt agcctccgaa ccgtgcttaa
     3541 cctcgaagtt ttcaacttgc ttttctacat ggctcagaat agctgaacgt ttgccatcag
     3601 ggctggtcgc gattgtataa ggatcacgtg tcagtgtttg gtgatgaggg aattggactt
     3661 gatactgata agtcttacct accaaatctt cttcaacatc caaactccag acaccgattg
     3721 tattgtcctt atgattataa gagtagctat tgcctctttt catctcaaaa gtcttccaaa
     3781 cgggtgcatc attagcagct gattcataaa cgacaacttg cacttctgtc gctgtaggtg
     3841 accagaggga aaaatgagcc tgattgtcct ctacacggca acccaattct ccttggtaac
     3901 cccaatgatg atcaaaacta gcactgttaa tggccttatc aaaggcaaaa ggattttgat
     3961 ttttatagaa aggactggca atagcaggat tttcagagta ataaatccta tcatcgcctt
     4021 ccaaaatcca gacctctgtc aataggggat agtgattaaa acggatagaa tattctttac
     4081 tagtttgacc tgtatgaacc acaaaattca agctttctat aacatgtgaa cttgggtgtt
     4141 caaagctaaa taaagctcca aaataatctt ctttgtaggt tagcaaatca attcgttgat
     4201 cctgactttt tacaaaggag caagtgtcat attctccatt cttacgatgg taatgaatgc
     4261 gcatagggta gttatacatt ttttattttt cctttttact ttgtttctat ttcactaata
     4321 aatttttgtc aatctcgtct caattaacag acatagtcat attctctaaa ctctgttttt
     4381 aaacgatcca ttacaaactt tctagccatg cctcatctct gacctggata ccaagttctt
     4441 gtgctttttg cagtttactt ccagcgtctg cacctaccac gacgaggtcg gtctttttag
     4501 aaacactacc tgtcactttg gcacccagac tttcgagttt acttttagct tctgagcgct
     4561 tgagtcgttc caattttcct gtcaatacca cggtcaaacc tgacaaggcc gcatccgcta
     4621 ctaccgtctg tcctttatag tccagattga ccccagtttc tttcaattct ctgagcagaa
     4681 tttcagagcc ttctgtcgca aaataagtct gaagactttt ggcaatcacg ccacctagac
     4741 tttcaatact agccacttcc tctgaatctg cctgatacag attttcaatt gaatggaaat
     4801 attgaagtaa aagctgacta gccttgcttc cgacatgacg aattcccaaa ccaaataaga
     4861 gcttctcggc agaattttcc tttgatgctt ggatagcctg atacagttta gcagcggact
     4921 tttccttaac cccctctaaa aggaggaaat cctcttcttg caaacgataa atatccgcca
     4981 catccttgac taaattagca gcaaaaagct tctcaacaat agatggacca aggcctgtaa
     5041 tattcatagc atcacgagaa gcaaagtgaa tcaagccttc catgatttga gcagggcaac
     5101 gcggattgat acaacgtagg gccacttcat cttcaaagtg caacaagtca gagttacaac
     5161 ttggacagtt tgtagggata tctagttttt cttcagaaac ccgtttggac tctaccacac
     5221 gtaaaacggc agggatgatg tcaccagcct tatatacaat gaccgtatcg tcttttcgga
     5281 tatctttttc agcaatataa tctacattgt gcagggtcgc acggctaaca gtcgtaccgg
     5341 caagttgtac tggtgttaga ttagcagttg gagttacaac accggtacgg ccaactgtcc
     5401 agtcaactga taagagttga gcttcttttt cttcagcagg gaacttgtag gctactgccc
     5461 actttggagc cttaacggta aaaccaagtt cttcttgact tgctaggtcg ttgaccttga
     5521 ttaccactcc atcaatatcg taaggcagat tttcccgttc ctgtcctact tcttggataa
     5581 aattccagat ttcatctatg ttttcagcca agattcgctt aggattgacc acaaaaccta
     5641 gttgttctag gtacttcaaa cccttttctt ggctatcacg agttgaaggg ctggcttctt
     5701 gatagagaaa cgttgcaaga ttacgcttgg caactactgc tgtatccaac tgacgcagag
     5761 ttcctgctgc cgcattacga ggattagcaa attcaggctc tccattttct tggcgcactt
     5821 ggttaacttg gtcaaaggaa gcgcgtggca tgtaacattc cccacgaact gtgatatcta
     5881 gttcttctgg caaagtcaaa gggatgtcct taacacgctt gaggttttct gtgatatttt
     5941 caccaattga accatctcca cgtgttaccc cagcaaccaa aatccccttt tcataagtca
     6001 gcgagataga taagccatcg attttcagct cacaaatata ggtcggatga gccacttcct
     6061 tacgaacacg cgcatcaaaa gcatctagct cctcacgtga aaaagcatcc tgcaaactat
     6121 aaagaggata ctgatgactg tatttttcaa aaccatctaa aaccttgcca ccaacacgat
     6181 gagtcggact gtctgctagc acttgctctg gataagcagt ttctaactcg accaactcac
     6241 ggtaaaggcg gtcatactca ctgtctgaaa ccgagggatt atcgctggta tagtactcag
     6301 tcgcatagcg attgagcaaa gcgactaact cattcattct tttattcata agaccatttt
     6361 accataaaac aaaccctcct cacaaacgag aaggacggaa aaaacactta gtttgaaatt
     6421 atttttgaaa ctcaagcaac cttatatcaa tttttcaaaa tgagttcgaa cataaataaa
     6481 cgatatacaa gacaagatga taacaccact tccaattatc aggaaagaag agagatgtac
     6541 acttggcaag actgtcataa atccttttgc aataggcata aatagaatag ctaaggtaaa
     6601 aattgtactc agtactctcc caagaaattc gctctcaacc ttggtttgta cttgagtaaa
     6661 aaagtgaata ttaaaaatcg tcataaacaa ttcacaaact aaatttccag aaaaggaaag
     6721 aaaagttgga agtggtaatc ccatcataaa aactccgaca cctgtcaaag ccagtaaaat
     6781 caaaagatta taaatattag ctttaatttt actagctaga agagccccaa tgatggaacc
     6841 aatagccccc atagttaaaa tacttgcata ggctccttct gacccgtaaa gctgattcga
     6901 aaagggaagt agaaattcaa aagctgcaaa aaagaaatta acgctggaag ctaccagcaa
     6961 aaggaagaaa atttcttgct gatgccagat atagtgtaac ccatccttga tatctacaaa
     7021 aatatctctc ccagtaaaag cctttttctc ttgaactttt gcttcctctt ttggaaggaa
     7081 agccactaga acaaaagcaa tgaaaaaagt cagcgagtct agcagtagcg tcatatggag
     7141 acttgcaaac tgtaaaacaa ggaaggaaag aacaggagag ctaacaccta caacctgcaa
     7201 aaccagctct aagcgagaat tatagatcac aatctcatct ttctccacca cttcagttat
     7261 gatagcttta ttggctgtgc gagaaaaggc aaaagcaata gcctgcacaa tgttagcaac
     7321 aatcaaagcg ccaatcatcc agctatcatt ccttatgaaa gaaatagcca gacaaagaat
     7381 cccacaaaca agatctgccg tcattaaaat cttacgacga gaaaaacggt ctgaaataac
     7441 tccgccaaag ggattgacga gaatagatgt gacgagctca gaaatctgat acattcctaa
     7501 aactgtctgt cctatagtcc ccatagaagc caaccagaca ctatttccat aatcatagag
     7561 catatttccc attttattga tagccccacg gctaatcaac tgcactgcat agcgattcat
     7621 attaaagctc ctctcaaatt ttgaaactat tgtatcaaaa ccgaaaggag ctttttattt
     7681 tttcccttat ttgggaaaat taacttttga caaatttttc gtagtgttcc tgataatagg
     7741 ctacttgctc tggaagacct aacacatcaa aaatatgtat ggcctcttgc atctgcttac
     7801 agccttcttt acactgtcct ttttgatata aggcaaaacc ttttaaataa tggaaaacat
     7861 tacgctcata aagcttaata cctttgtcaa taatcttctc tgtataagcc tcaaaatagt
     7921 tggcattata aaaagaagaa tgctctaaac aatgctggta acaattgagg gccaaaatca
     7981 aaactaatct cttatggcga ctaatctctt ggtaaaattc ctccctctcc ataacttctc
     8041 taccaatccg agtgacatag tctacatcgt agaaactata gaggttaccg aaaagaatca
     8101 actcatacat ggtccattct tctgttttga agagataatc tgctacctta tccaaatcat
     8161 cctgcttcat atcataactc gcatctcttt gacaaatcag accttgtagc aaaatccagt
     8221 tcagctcaaa ataaagggga gtcgtcgaac tcttagactt ttcaagttgt tctctttgaa
     8281 gcttttgaaa acctgcaata tcgtttgaat agtaaagtgg gataatctgt gccatcatag
     8341 acacatgttc atgattgtga aaattccttg ccttatccat gaaattttcg attgttacat
     8401 gaatgttatc caaaatctca aagaaacggg agactgccag gtcagactcc ccaagctcaa
     8461 agcgagataa ctgagaggta gagcaggatt cgcctgctgc ttcctttaaa gaataatttc
     8521 cacttgttcg aaattcacga aatacttttc caagatgttc catctttaca cctgatctga
     8581 taattcttcc cactcaagca tagcttcttc ctgacgatgg ctgattttgt ccagctcagc
     8641 ctgtaattcc atgagtttgt cggcatcgtt tgtttccaac atttgttcag aaatggcttg
     8701 gctttgactt tctagctctt caatttcagc ttctagactt tcgatttgtc gcatgagttt
     8761 gcgaacttct ttttgacttt ctttctgggc ctgatagtca ttgactggac ttgcttcctt
     8821 tgcttgattg ctagttgaag cttcctcagt ctgactcatt tctgctgttg ctttcttctc
     8881 aacatagtag tcgtaatctc caaggtagag agttgaacca ttctcagaca attccaaaac
     8941 atgagttgcc acacgattga taaagtaacg atcatgactg acaaaaagca aggtaccatc
     9001 aaagtcaatc aaagcatttt ccaacacttc cttgctatca atatccaagt ggttggtcgg
     9061 ctcgtcaagg atcaggaagt tgttgttttc catagacaat ttagctaaaa gcaaacgagc
     9121 tttttcgcca ccagatagca tgccgactga ttttttaaca tcatctcctg agaaaaggaa
     9181 ggctccaaga cggttgcgga tttcaacttc tggtgtcagt ttgaaatcat tccagagttc
     9241 atccagcacc gtattacttg gtgtcagctt gctttgggtt tggtcatagt aaccaacctc
     9301 aacattagcg ccaaagcgct tttcaccttt gataaaagga atctggtcca caatagactt
     9361 gataaaggtt gacttgccga taccatttgg accaacgata gcgacagcat tcatcttacg
     9421 aagatctagg ttgataggtt gtgacaagac ttccccgtca taaccaatag cagtattttc
     9481 aacagtcaaa acaacattgc ccgacgtttt ttcagactgg aaggtcatgt tggctgcttt
     9541 cttgccagct tcaggcttgt ccaaacgctc cattttttct agttgtttac ggtgagattg
     9601 agcacgttta gtcgttgaag cacgaactag attgcgattg acaaagtctt ccagagcagc
     9661 gatttccttc tgttgctttt catagttttt tgcctcagta actagctttt gctccttcaa
     9721 ttcgacaaaa cgagagtaat tccccacata gcgatccaag gaatgcttgg tcaaatctag
     9781 cgtaattgtc gcaaccttgt ccaagaaata acggtcgtgg ctgacgataa tgagggcacc
     9841 gctatagttt accaagtaat tctctagcca ggcgatggtt tcaatatcca agtggttagt
     9901 tggctcgtcc aagaccaaga gattgggctt ttcaaggagc attttggcaa gtgccaaacg
     9961 agtattttga ccaccagaaa gctcagcaat tttcatctgc cacatagact cgtcaaactt
    10021 gaatccattc aaaatcgctc gaatatcagc ttcataggta aagccacctg cttggcgaaa
    10081 attctcagat aagcggtcat aatctgacat cagtttatcc aaatcctcac cagacttttc
    10141 acccatctcc agctccatct gacgcagttg tctctccgtc cgacgcaaat tattaaagac
    10201 atgaagcatt tcatcgtaga tggtattttc agactcaaaa cggctatctt gggctaggta
    10261 agacagagaa atatcttttt tcttattgat ttctccgcta gttggctcct cttctccaac
    10321 taaaatcttc aaaagagtag acttacctgc accatttttc ccaacaaggg caatccgatc
    10381 tcgttcatca acctgcaggt tgatattatc gaaaagaacc tctcctgcaa aagaacgttc
    10441 aattttatta gcttgtaaaa taatcataag agtagtatag catgtttccc taaggcattc
    10501 aagataatcg taagtctttt agtacaactt ttataacata aaataaacta aattatgtat
    10561 attttatatt agattcttca ctatcttgtt ggattttcta accagctaat cttgtttcaa
    10621 atagttatcg cacaagccta ttatttaatt ctttt
//
LOCUS       DAVMCG010000057        10430 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVMCG010000057 DAVMCG010000000
VERSION     DAVMCG010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10430
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.058"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            29..5266
                     /locus_tag="VYP66_001875"
     CDS             29..5266
                     /locus_tag="VYP66_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1851372.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSIFLGSFLFALSVVGVSTYHYLDYS
                     TLTQTERDQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTVLGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDR
                     TVSSVSPASTVSPVEQPKVVTDKGEPEVQPALPEAVVTEKGEPEVQPALPEAVVTEKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDNSVKQVSEDGERQIVT
                     SYEELHGKKISESVETVTILKEMKPEIIVKGTKEKTAPVLTLTKVTEDAMNRSANLNY
                     ELDNKDNAEISSIVAEIKDGDTVVKRVDLSKEKLTDAVQNLDWFKDYKIATTMIYDRG
                     QGSETSKLDERPLRLELKKVEIKNIASTNLVKVNDDGTETPSDFMNEKPSEEDVKKMY
                     LKITSRDNKVTRLTVDSIEEVTEEGQKLYKITAEAQDLIQHTDPTKVRNKYVYYIEKP
                     HPKEDNVYYNFKDLVDAMNTDKNGTFKLGADLNATGVPTPKKWYVDGDFRGTLKSVEG
                     KHYTIHNTERPLFQNIIGGTVTKVNLGNVNINMPWADRIAPIADTIKGGAKIEDVKVT
                     GNVLGRNWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVERAYV
                     DANLIGKKAKAAGIAYWTQNSGDNHKVGVEGAVKKGIVKGTIQVESPVEVGGAVGRLS
                     HHGYIGEVVSMMKVKKGEIFYGSSDMNDDPYWVANNVRGNYVVNGVSEGTISYARAKE
                     HHRIKPISQSEADTKIMMLGITAQDFAINEPVVNRLNRLTRKEDEYKSTQDYKVDRDL
                     AYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMV
                     HYADGTKEEMDVTKNADSKVKQVREYTIAGQNVVYTPNMVEKDRNQLIQDIKDKLASV
                     QLISPGVRALMDARKKPEENTDERKNGYIKDLYLEESFAETKANLDKLVKSLVENADH
                     QLNSDETAMKALVKKVDENKAKIMMALTYLNRYYDIKYGDMTIKNLMMFKPDFYGKSV
                     DLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFTNDTDLNDW
                     FIHAAKNVYVSEPQTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAHMFLISTYN
                     TMAYSSFEKYGKYTEEARNEFKKEIDKVAHAQQTYLDFWSRLALPSVRDQLLKSENRV
                     PTPVWDNQNYSGIKGINRMGYDEKKVPIAPIRELYGPTWKFHNTNWNMGAMASIFPNP
                     NNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAYAQGMLQTP
                     SSIGHQGEYGALGLNMAYHRENDGDQWYNYDPDKLQTREDIDRYMKNYNEALMMLDHV
                     EADAVLPQLNGDNSKWFKKIDREMRRNLGDGLNNLVAPHQWDNVRDLNQEESSKKLSS
                     INDLIDNNFMTKHGNPGNGRYRPEDFRPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKH
                     NAFRMWGYYGYDKGFTSYVSSKYQGEADKQNQGRLGDDFIIKKVSNNQFSNLEDWKKY
                     WYHDVKSRAEKGFTEITIDGQTIHNYNELKDLFDKAVTEDLKKAGNYSNTENLKSKVF
                     KALLKNTDGFFNPLFKKDI"
     gene            5434..6780
                     /locus_tag="VYP66_001876"
     CDS             5434..6780
                     /locus_tag="VYP66_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1851373.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSCLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKMDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
     gene            7195..8046
                     /gene="ylqF"
                     /locus_tag="VYP66_001877"
     CDS             7195..8046
                     /gene="ylqF"
                     /locus_tag="VYP66_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1851374.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            8033..8812
                     /locus_tag="VYP66_001878"
     CDS             8033..8812
                     /locus_tag="VYP66_001878"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1851375.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            8828..10378
                     /locus_tag="VYP66_001879"
     CDS             8828..10378
                     /locus_tag="VYP66_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1851376.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLRLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
BASE COUNT         3401 a         1869 c         2155 g         3005 t
ORIGIN      
        1 aataaaaagt gaatgtggag gattagaatt gtcattatta aaaaaagata aattttccat
       61 taggaaaata aagggtattg ttggttcgat attcttgggg agttttttat ttgcactgtc
      121 agttgttggt gtatcgactt atcattactt agattatagt actttgacac aaactgaacg
      181 tgatcaactc aaacaaggta gacctgatga atcaaaagag tcatatgctt tggtttatga
      241 aaaagacgca ttaccaaaca caggaagttc tcaatctatt atgactgtat tgggtttgtt
      301 agctatcggg agtcttattg tgattatcac aaaagataaa aagaggaaaa aaatagctac
      361 atttttgatt gtaggggcga caggtttagt tacactatca actgcttcag cacttaattt
      421 gaatgctaac atccatgagt ctggacgtga tggtgtgttg caaatttctg gttacagata
      481 tgttggttac ttggagcttg atgatagaac tgtttcgtcg gtttctccag catcaactgt
      541 ttctccagtt gagcaaccca aagttgtgac cgacaaaggc gaaccagaag ttcagccagc
      601 gttaccagaa gcagttgtaa ctgaaaaagg ggaaccagaa gtacaaccag ccttacccga
      661 agcagttgta actgaaaaag gggaaccaga agttcatgag aagcctgact atacgcaacc
      721 aataggtgca aaccttgttg agcctgaagt tcatgagaaa ctagcataca ctgaacctgt
      781 aggtacaaca ggagtagatg aaaatggaaa cttgattgag ccacctgtta acgatattcc
      841 agagtatact gaaccaatat ctacagtttc agaagttgca tcagaaagag aagagttgcc
      901 ttctttacat accgatattc gtacagagac tattcctaaa accactatag aagaatctga
      961 tcctagcaaa tttataggcg ataattctgt taaacaagtt agtgaggatg gcgaacgtca
     1021 aattgttact agctatgaag agttacatgg caaaaaaatc agcgagtcag ttgaaacagt
     1081 aacaattttg aaagaaatga agcctgaaat tattgtaaaa ggtacaaaag aaaaaacggc
     1141 tcctgtttta accttgacca aagtaacaga agatgctatg aatcgttctg ccaacttaaa
     1201 ttatgagctt gataataaag ataatgctga aatatcaagt attgtagctg aaattaaaga
     1261 tggtgataca gtagttaaaa gggttgattt atctaaagaa aaattaactg acgctgtaca
     1321 aaatttggat tggtttaaag attataagat tgcaacaaca atgatttatg atcgtggtca
     1381 aggttctgaa acgtctaaac tggatgaaag acctctgcgt ttggagttga aaaaggtcga
     1441 aattaaaaat atcgcatcta ctaatttagt gaaggtaaat gatgatggta ctgaaacacc
     1501 tagtgatttt atgaatgaaa aaccttcaga agaagatgtt aaaaaaatgt acttaaaaat
     1561 cactagtcgc gataataagg taactcgttt aactgtagac tctattgaag aagtgactga
     1621 agaaggtcaa aaactttaca aaataactgc tgaagcacaa gatttgattc aacacacaga
     1681 cccaacgaag gttcgtaata agtatgttta ttatatagaa aaaccccatc ctaaagaaga
     1741 taatgtctac tataacttta aagatttagt agatgctatg aatactgata aaaatggtac
     1801 atttaaactt ggtgcagatt tgaatgccac tggtgttcca acacctaaga aatggtatgt
     1861 tgacggcgac tttagaggta cattgaagag tgtagagggg aaacattata ctatccacaa
     1921 cacggagcgt ccgttattcc agaatattat tggtggtaca gtaaccaaag taaatctggg
     1981 aaatgtaaat atcaatatgc catgggcaga ccgcatcgca ccgattgctg acactattaa
     2041 aggtggcgct aaaattgaag atgtcaaagt gactggtaac gtattaggta gaaactgggt
     2101 atctggattt attgataaga ttgacaacca aggtacactc agaaatgtag cctttatcgg
     2161 aaatgtgaca tctgtaggtg atggtggtca attcttgacc ggtatcgttg gtgagaactg
     2221 gaaaggacta gtcgaacgtg cgtatgttga cgcaaatctt attggcaaga aagccaaggc
     2281 tgctggtatt gcttattgga cacaaaacag tggtgacaat cataaagttg gtgtcgaagg
     2341 tgcagtcaag aaaggaattg tgaagggtac cattcaggta gaaagtcctg ttgaagtcgg
     2401 cggtgctgtt ggacgtttga gtcatcatgg ttatatcggg gaagtcgtat ctatgatgaa
     2461 agttaagaag ggtgaaattt tttatggttc tagtgatatg aatgatgacc catattgggt
     2521 ggcgaataat gtacgaggaa attatgtcgt taatggtgtg agtgaaggta cgatatctta
     2581 tgctcgtgct aaagaacacc atcgtatcaa accaatttca cagtcagaag cagatactaa
     2641 aattatgatg ttaggtatta cagcacaaga ttttgctatc aacgaacctg tggtcaatcg
     2701 cttaaaccgt ttaaccagaa aagaagatga atataagtca acccaagact ataaagtaga
     2761 tcgagatctg gcttatcgta atattgagaa acttcaacca ttttataaca aagaatggat
     2821 tgtcaaccaa ggtaacaaac ttgcagaaga ttcaaactta gctaagaaag aagtcctttc
     2881 tgttacgggt atgaaggatg gacagtttgt aactgactta tcagatattg ataagattat
     2941 ggttcactat gctgatggta ctaaagaaga aatggacgtc actaagaatg ctgattctaa
     3001 agtgaaacaa gttcgtgaat ataccatcgc tggacaaaac gttgtttata caccaaatat
     3061 ggttgagaaa gaccgtaacc aattgattca agatatcaaa gataagttgg cgtcagttca
     3121 attgatttct cctggagtac gtgctttgat ggatgcacgt aagaaaccag aagaaaatac
     3181 tgatgaacgt aagaatggtt atattaaaga cctttactta gaagaaagct ttgctgaaac
     3241 gaaagctaat cttgataaat tggttaaatc cttagttgaa aatgcagatc atcaattaaa
     3301 tagtgacgaa acggctatga aagcacttgt taagaaggtg gatgaaaata aagctaaaat
     3361 catgatggct ctgacttatc tcaatcgtta ctatgatatc aagtatgggg atatgactat
     3421 caagaacttg atgatgttta aacctgattt ctatggtaaa tcagttgacc ttcttgattt
     3481 cttgattcga attggatcaa gtgagagaaa tatcaaaggt gacagaactt tggatgctta
     3541 tcgtgatatg attggtggaa ctattggtaa gtctgaatta catggattct tagattacaa
     3601 tatgcgtctc ttcactaacg atactgattt aaatgattgg ttcatccatg cagctaagaa
     3661 tgtatatgta tcagaacctc aaacaacgaa cccagatttt gttaataaac gacatcgtgc
     3721 atttgatggt ttgaacaacg gtgttcataa tcgtatgatt ctacctctat taactcttaa
     3781 gaatgcacat atgttcttga tttcaactta caatacaatg gcttatagtt cttttgagaa
     3841 atatggtaag tatacagaag aagctagaaa tgaattcaaa aaagaaattg ataaggttgc
     3901 acatgctcaa caaacatact tagacttctg gtcacgttta gcattgccaa gcgtacgtga
     3961 ccaattactc aagagtgaga atagggtacc aactcctgtg tgggataacc aaaactatag
     4021 tggtattaaa ggaataaacc gtatgggtta tgatgagaag aaagtaccaa ttgcgccaat
     4081 tcgtgagtta tatggtccaa cttggaaatt ccataatacc aactggaata tgggagctat
     4141 ggcatctatt ttcccaaatc ctaataacaa tgaccaagtt tatttcatgg gaacaaatat
     4201 gattagtccg tttggtattt cagcctttac tcatgaaact acacacgtta atgatagaat
     4261 gctttacttc ggtggtcata gacaccgtca aggtacagac gtcgaagcct atgctcaagg
     4321 tatgctacaa actccgtcaa gtattggtca ccaaggtgaa tatggtgctt tgggtttgaa
     4381 catggcttat catcgtgaaa atgatggtga ccaatggtat aactatgacc ctgataagct
     4441 tcaaactcgt gaagatatcg atcgatatat gaaaaactat aatgaagcac tgatgatgct
     4501 agatcatgta gaagcagacg ccgtacttcc acaattgaat ggtgataata gcaagtggtt
     4561 caagaaaatt gatagagaaa tgcgcagaaa tcttggggat ggtttgaata acttagtagc
     4621 accgcaccaa tgggacaacg ttcgtgactt aaatcaagaa gagagttcta agaaattatc
     4681 aagtattaac gatttgattg ataataattt catgaccaaa cacggaaatc caggtaacgg
     4741 acgttataga ccagaggatt ttagaccaaa ctcagcttac gtaaatgtca atatgatggc
     4801 aggaatttac ggtgggaata cgagtcaagg tgctcctggt tcattatcgt tcaaacataa
     4861 tgccttccgt atgtggggtt attatggata tgacaaaggt ttcactagtt atgtatctag
     4921 caaatatcaa ggtgaagctg ataaacaaaa ccagggtaga ttaggtgatg atttcattat
     4981 caaaaaagtt tcaaacaacc aattctcaaa tcttgaagat tggaagaaat attggtatca
     5041 tgatgtgaaa tccagagctg aaaaaggatt cacagagatt acaattgatg gacaaaccat
     5101 tcacaactat aatgaactga aagacttatt cgacaaagct gtcacagaag acctcaagaa
     5161 agctggaaac tactcaaata ctgagaattt gaaatccaaa gtcttcaaag ctcttcttaa
     5221 aaacacagac ggtttcttta atccattgtt caaaaaagac atttaaaccc caattattca
     5281 ccccaaatct aaaaaccatc cagaatcctt gccttagctt agatcctgga tggtttcttt
     5341 ttcacccaat gggtgttttt tactagacaa aaaagagttt cccctttatg gtataagtgt
     5401 agaaaaaaaa acacaaaaag aaaggaaact cacatgaaca gtttaccaaa tcatcacttc
     5461 caaaacaagt ctttttacca actatctttc gatggaggtc atttaaccca gtatggtggt
     5521 cttatctttt ttcaggaact tttttcccag ttgaaactaa aagagcggat ttctaagtat
     5581 ttagtaacga atgaccaacg ccgctactgt cgttattcgg attcagatat ccttgtccag
     5641 ttcctctttc aactgttaac aggctatgga acggactatg cttgtaaaga attgtcagct
     5701 gatgcctact ttccaaaatt gttggaagga gggcagcttg cttcacagcc aaccttatcc
     5761 cgttttcttt ccagaactga cgaggaaaca gtccatagtt tgcgatgcct caaccttgaa
     5821 ttggtcgaat tctttttaca gtttcaccag ctaaaccaac tcattgtaga tatcgattct
     5881 acccatttca caacttatgg caagcaagaa ggtgttgctt ataacgccca ctatcgtgct
     5941 catggctatc atcctcttta cgctttcgag gggaagacag gttattgttt caatgcccag
     6001 cttcgtcctg gtaatcgtta ttgttctgaa gaggcagaca gctttatcac acctgtttta
     6061 gaacggttta atcaacttct ctttcgaatg gatagtggct ttgcgacccc aaaattatac
     6121 gatttaattg aaaaaacagg gcaatactac ctcataaaac tcaagaaaaa tactgttctg
     6181 agctgtcttg gagacctttc cctcccttgc ccacaggatg aggacttaac catcttgccc
     6241 cactccgcct actcagaaac tctctatcaa gcaggatctt ggtcgcacaa gcgtcgtgtc
     6301 tgccagttct ctgaacgaaa agaaggaaac ttgttctacg atgttatttc tctcgttaca
     6361 aatatgacga gtggaacaag ccaagaccag tttcagcttt atcgtggacg tggtcaagcc
     6421 gagaatttca tcaaggagat gaaggaggga ttttttggcg ataaaatgga tagttcaacc
     6481 ttaatcaaaa acgaagttcg tatgatgatg agctgtatcg cctacaatct ctatcttttt
     6541 ctcaaacatc tagctggagg tgacttccaa actttaacaa tcaaacgctt ccgccatctt
     6601 tttcttcacg tggtaggaaa atgtgttcga acaggacgca agcagctcct caaattgtct
     6661 agtctctatg cctattccga attgttttca gcactttatt ctaggattag aaaagtcaac
     6721 ctgaatcttc ctgttcctta tgaaccacct agaagaaaag cgtcgttaat gatgcattaa
     6781 agaacagtcg agatgaaaaa atcgtgtgac gtaccaaggg aggagtctgc ccttttgagg
     6841 aaatctagcg aggaaaaacg atactggaac agcagaaagt aaaactgacc tcatgaggac
     6901 atgaggtcag gggttttgta agttacatct agttgagaga ggtatgaatg atttgggtta
     6961 aatgtttaaa acataaagag gacagttttt tgctccctct gaaaagtcat catttgatgg
     7021 cttttttcta tatagggtaa aaggctatca tcggacaaaa taaagaaggc atgatataat
     7081 ataaagtaga tttttatgtc ataaaacaag aactgtttgg acatcattca tttttagatt
     7141 gagatctctt agttctagat taacagcttc agagctacga aaggaaaaaa ctcaatggct
     7201 actattcaat ggtttcctgg tcacatgtct aaagctcgtc gacaggtgca ggagaattta
     7261 aaatttgttg attttgtgac gattttagta gatgcacgct tgcctctatc tagtcaaaat
     7321 cctatgttga ccaagattgt tggtgataaa ccaaaactct tgattttaaa caaggccgac
     7381 ttggctgatc cagcaatgac caaggaatgg cgtcagtatt ttgaatcaca aggaatccag
     7441 acgctagcta tcaactccaa agagcaagtg actgtaaaag ttgtaacaga tgcggccaag
     7501 aagctcatgg ctgataagat tgctcgccag aaagaacgtg ggattcagat tgaaaccttg
     7561 cgtaccatga ttatcgggat tccaaacgct ggtaaatcaa ctctgatgaa ccgtttggct
     7621 ggtaaaaaga ttgctgttgt tggaaacaag ccaggggtca caaaaggtca acaatggctt
     7681 aaaaccaata aagacctgga aatcttggat acaccgggga ttctctggcc taagtttgag
     7741 gatgaaactg ttgcacttaa gttggcattg actggagcta tcaaagacca gttgcttcct
     7801 atggatgagg ttaccatttt tggtatcaat tatttcaaag aacattatcc agaaaagctg
     7861 gctgaacgct tcaaacaaat gaaaattgaa gaagaaccgt ctgtgattat tatggatatg
     7921 acccgcgccc tcggtttccg tgatgactat gaccgttttt acagtctctt cgtgaaggaa
     7981 gtccgtgatg gcaaactcgg taactatacc ttagatacat tggaagacct cgatggcaac
     8041 gattaaagaa atcaaagaac tccttgtgac agtcaaggag ttagaaagcc ctattttttt
     8101 agagcttgaa aaggataatc gctcaggagt tcaaaaggaa atcagcaagc gtaaaagagc
     8161 catccaagct gaattagatg aaaatttgcg cttggaatcc atgctttctt atgaaaaaga
     8221 actttataag caaggattga ccttaattgc aggtattgat gaggttggtc gtggtcctct
     8281 tgctggtcct gtagtcgctg cggccgttat tttacctaaa aattgtaaga ttaaaggtct
     8341 caacgacagc aagaaaattc ctaaaaagaa acatctggag attttccaag ccgttcaaga
     8401 ccaagccttg tcgattggaa ttggtatcat agataatcag gtcatcgacc aagtcaacat
     8461 ctatgaagca accaaactag ccatgcaaga agcaatctcc cagctcagcc ctcaaccaga
     8521 gcaccttttg attgatgcca tgaaactgga cttgcccatt tcacaaacct ccattatcaa
     8581 aggagatgcc aactccctct ctatcgcagc agcatctata gtagccaagg taacacgtga
     8641 tgaattgatg aaagaatacg atcagcagtt ccctggctat gatttcgcta ctaatgcagg
     8701 atatggcaca gctaaacatc tggaaggcct cacaaaacta ggagttaccc caattcaccg
     8761 aaccagcttt gaacccgtta aatcactggt tttaggtaaa aaagaaagtt aattgaaagg
     8821 aaataccatg gaggaacagt cggaaatagt ccgttctaag aaagaattcg cctttgcatc
     8881 cagcactata ctatcccaag ttggtcgagg aatcattgtc ggcctcatcg ttggaattat
     8941 cgtcggatcc tttcgtttct taattgaaaa gggcttccac atgatacaag gagtttatca
     9001 agatcaaggg tacttagtgc gcaatctttt tgtactggtt ttgttttata tactcatctg
     9061 ttggctcagt gccaaactaa cacggtcaga aaaagatatt aaaggctcag gaattcctca
     9121 agtcgaagcc gaactgaaag gcctcatgtc cctcaactgg tggggcattc tttggaaaaa
     9181 atatgtgcta ggtattctcg ctattgccag tggactcatg ctgggtcgag agggacccag
     9241 tattcaactt ggagcagttg gtggtaaagg aattgccaag tggctcaaat ccagtccagt
     9301 agaggaacgt tccttgattg ccagtggagc tgcagcaggt ttagccgcag cctttaatgc
     9361 tcctattgca gcacttctct ttgttgtaga agaagtctat caccattttt cgcgcttttt
     9421 ctgggtctca actctagcag ccagcatcgt agcaaacttt gtgtctctac tcatgttcgg
     9481 tttgacacca gtattggata tgccagataa cattcctccc atgaccctag atcagtattg
     9541 gatatatctc gtcatgggaa ttttccttgg attttcaggc tttctctatg agaaagctgt
     9601 attaaacgtt ggaagagttt atgacttgat tggtcaaaaa atccatttgg atagagctta
     9661 ttatcccatc ttggctttta tccttatcat accagtcgga atcttcttac ctcaaatcat
     9721 tggtggcgga aatcagcttg tcctttcttt aactgaacaa aattttagtt tccaagtttt
     9781 attagcttac tttttgatcc gctttatttg gagtatgatt agctatggaa gtggactgcc
     9841 aggaggaatt ttcctcccca ttttagctct tggttctttg cttggtgcct taattggtgt
     9901 tatctgtgtc aatcttagac ttgtcagtca agagcaattc cctatatttg tcattctagg
     9961 aatgagtggc tattttggag ccatatcaaa agctccctta accgctatga tcctcgtaac
    10021 tgagatggta ggagatattc gcaacctcat gccacttggt cttgtcactc ttgtttctta
    10081 tattatcatg gatttgctca aaggtacgcc agtctatgaa gccatgctgg aaaaaatgct
    10141 tccagaagaa gtatctagcg aaggagaagt tacacttatc gaaataccag tttctgataa
    10201 aattgctggg aaacaagttc atgaactcaa cttaccacac aacgtcctca tcacaactca
    10261 agtccataat ggcaagagcc aaacagttaa cggctcaacc agaatgtatc tgggtgatat
    10321 gattcacctg gttattccaa aaagtgaaat tggaaaagtc aaagatttgt tgttgtagta
    10381 caatcattta cataatttat attatgtaaa tgattggctt gatttattta
//
LOCUS       DAVMCG010000058        10226 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVMCG010000058 DAVMCG010000000
VERSION     DAVMCG010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10226
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.059"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            89..1264
                     /gene="mutY"
                     /locus_tag="VYP66_001880"
     CDS             89..1264
                     /gene="mutY"
                     /locus_tag="VYP66_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1851377.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATASEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYVQANLDSSQD"
     gene            1319..2023
                     /locus_tag="VYP66_001881"
     CDS             1319..2023
                     /locus_tag="VYP66_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1851378.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2016..3365
                     /gene="vicK"
                     /locus_tag="VYP66_001882"
     CDS             2016..3365
                     /gene="vicK"
                     /locus_tag="VYP66_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1851379.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRIRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3367..4176
                     /locus_tag="VYP66_001883"
     CDS             3367..4176
                     /locus_tag="VYP66_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1851380.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4267..4509
                     /locus_tag="VYP66_001884"
     CDS             4267..4509
                     /locus_tag="VYP66_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1851381.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4511..4765
                     /locus_tag="VYP66_001885"
     CDS             4511..4765
                     /locus_tag="VYP66_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1851382.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4812..5585
                     /locus_tag="VYP66_001886"
     CDS             4812..5585
                     /locus_tag="VYP66_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV1851383.1"
                     /translation="MKKKWFFVDYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5833..6819)
                     /locus_tag="VYP66_001887"
     CDS             complement(5833..6819)
                     /locus_tag="VYP66_001887"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1851384.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7013..9481
                     /gene="gyrA"
                     /locus_tag="VYP66_001888"
     CDS             7013..9481
                     /gene="gyrA"
                     /locus_tag="VYP66_001888"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1851385.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLTEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9481..10224
                     /gene="srtA"
                     /locus_tag="VYP66_001889"
     CDS             9481..10224
                     /gene="srtA"
                     /locus_tag="VYP66_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1851386.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         3167 a         1730 c         2284 g         3045 t
ORIGIN      
        1 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
       61 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
      121 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
      181 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
      241 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat tcctggactg
      301 gtttccaact gtcgaaagtc tggcaactgc gtctgaggag agtttactga aagcttggga
      361 gggcttgggc tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
      421 tgactttggt ggccaatttc caaataccta tgaaggaatt tccagcttga aagggattgg
      481 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
      541 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
      601 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccgg atcgtccggg
      661 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
      721 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
      781 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
      841 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
      901 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
      961 ctttcatcag gttgcggaag aaagtgtgaa ctttggtccc agtccagaag agagtttcca
     1021 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
     1081 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
     1141 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
     1201 caaaccccaa caaaaaatct ggcaggctta tgtacaagcc aacttagaca gtagccaaga
     1261 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
     1321 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
     1381 gaccaaggaa ggttacgaag ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
     1441 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
     1501 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
     1561 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
     1621 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
     1681 tatgccagta gatgggcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
     1741 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
     1801 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
     1861 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
     1921 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
     1981 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
     2041 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
     2101 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
     2161 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
     2221 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
     2281 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
     2341 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
     2401 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
     2461 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
     2521 atggcgaata tttgaacctt cgaattcgct ttgccttgat acgtcgagag tctggcttta
     2581 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgcgaac
     2641 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
     2701 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
     2761 aggtttctct tgatgaaacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
     2821 cacgtattga taatgctacc agtcatctag atgtggaact gattaacttc actgctttta
     2881 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggaa aaaaaatatg
     2941 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
     3001 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
     3061 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
     3121 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
     3181 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
     3241 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
     3301 ttgtgcttcc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
     3361 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
     3421 tctttttatc tggaaacctc aaaaaagaag cttttagtgg atgcaggctt gtctggcaag
     3481 aaaattacca gtctgctagc tgaaattaac cgcaagccag aagacctgga tgccatcttg
     3541 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
     3601 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
     3661 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ttttggagat
     3721 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
     3781 atgaaggatg acaagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
     3841 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagaaatt
     3901 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
     3961 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
     4021 atttaccttg ggcatttatc taaggaaaat aatatcaagg aactggctca tatgaccatg
     4081 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
     4141 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
     4201 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
     4261 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
     4321 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
     4381 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
     4441 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
     4501 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
     4561 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
     4621 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
     4681 taattatcga gttattgtac aaattgtaga tgatgaatta gtcgttgcta ctctagaagt
     4741 tggtcatcgg agagatattt attaaattaa agctgagtaa taacagtata gaaagtaagg
     4801 agagtaaaaa tttgaagaaa aaatggtttt ttgtagatta ttatgataca acaattattt
     4861 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
     4921 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
     4981 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
     5041 tattggctat tctcccttta aatgctattt ttacagtgtt tcgattaggg cgtatctttc
     5101 gtttagctaa actaacaaaa ttactgaaac tgactcgttt acttagaata attggactta
     5161 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
     5221 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     5281 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggatatgggg
     5341 atattgttcc tgcttccatt tttgggaaat ggctagcagt tttactgatg cttgtcggta
     5401 ttggaacaat agggatgtta acaagtgctt tgacgaactt ttttgtaaag gataatccag
     5461 atgaacagat aaaacttgat aaactccaag atgaattatc tagtcagaga atattactag
     5521 agaaacaatc taaaaagata gaagaactac ataaaatgat acaagatttg attgaaaaaa
     5581 cataataaaa ataaagatga gacaaagttt gagctgagga gaaatcaagt aagttttgac
     5641 acaatagaac gcatattatc aggtataaaa acttgatact atgcgtttta tagagaaata
     5701 aaataaaatc tgaacaaatc aattaggaat ttaaagcatt ttataacaac gttttagagt
     5761 aacggggtac tatttcatat aatacaggaa aaaacaactc cctgatgatt caaggagttg
     5821 tctatagtta aattagtttt tagaagcttc ttggaattct ggatttttcc atgcttcgtc
     5881 aataatagct tgcaattctt tagcagatgc ttgcattttt tgagtttctg catcgttcaa
     5941 tggaatgttt actggacgaa cgataccatg tgcaccaaca acagctggtt gaccgataaa
     6001 gacattctca actccgtatt gaccttcttg gaatactgaa agtggaagta ctgcgttttc
     6061 atcgtcaagg attgctttag tgatacgagc aagggctact gcgataccgt agtatgttgc
     6121 accttttttg ttgatgattg tgtaggctgc atcacgaaca ccttcgaaca attcaatcaa
     6181 ttcagcttct tgaacatttt gagtatcttt aaggaattct tcaaggttta caccagcgat
     6241 gttagcgtgc gaccaaacag cgaactcaga gtcaccgtgt tcacccatga tgtaggcgtg
     6301 aactgaacga gcatctacgt ccaatttttc agcaagtgct tgacggaaac gagctgagtc
     6361 aagtgaagta cctgaaccga taacgcgttc tttagggaaa ccagagaatt tccaagttga
     6421 gtaagtcaaa acgtcaactg ggttagcagc aacaaggaag atacctttga aacctgattc
     6481 aacaacttga gttacgattg atttgttgat agcaaggttt ttacctacaa ggtcaagacg
     6541 agtttcacct ggtttttgag gtgcacctgc agtgatcaca acaaggtcag cgtctgcaca
     6601 gtcagagtat tgagctgcat agattttttt aggtgaagtg aaggcaaggg cgtgactaag
     6661 gtcaagcgca tcaccaacag ctttttcatg caattgtgga atttcgataa ttccaagctc
     6721 ttgtgcaatt ccttggttaa caagtgcaaa agcgtaagat gaacctacag caccatcacc
     6781 gacaaggata acttttttgt gttgtttagt tgaagtcatt gttttaaaca tctccttaat
     6841 tttattaggg gattttccct agacaacttc attctatcac ttttaaaaaa ctttgtcacg
     6901 aatatgcctt atagttctcg atgtaaacgt tttagtggtt tagaggctga aatagatggg
     6961 aatttatggt ataatgttgt tacttactaa ttgtgaaatg aggcatttat taatgcagga
     7021 taaaaattta gtgaatgtca atctgacaaa ggagatgaag gcaagtttta tcgactacgc
     7081 catgagtgtt atcgtagcgc gagctcttcc tgatgttcga gatggcttaa aacctgttca
     7141 ccgtcgcatt ctctacggaa tgaatgaatt gggtgtgacc ccagacaaac cccataaaaa
     7201 atctgctcgt attacagggg atgtcatggg taaatatcac ccacacgggg attcctctat
     7261 ttatgaagcc atggtccgta tggctcaatg gtggagctac cgttacatgc ttgtagatgg
     7321 tcatgggaat tttggttcca tggatggaga tagtgctgcc gctcaacgtt ataccgaggc
     7381 acgtatgagc aagattgctc tggaaatgct tcgtgatatc aacaaaaata cagttgattt
     7441 cgttgataac tatgatgcca atgaacggga acccttggtc ttgccagcgc gttttccaaa
     7501 ccttttggtt aatggagcaa ctggtatcgc ggttgggatg gcaaccaata ttccacctca
     7561 taatctgggt gaaaccattg atgcagtgaa gttggtcatg gataatcctg aagtgactac
     7621 caaggacttg atggaagtct tgcctggacc agattttcca actggtgctc ttgtcatggg
     7681 gaaatcaggt atccataagg cttatgaaac aggtaaaggt tcgattgtcc tacgttctcg
     7741 tacagagatt gaaacgacta agactggtcg tgagcgtatc gttgtaacag aatttcctta
     7801 catggtcaat aaaaccaagg tgcatgagca tattgttcgc ttggttcagg aaaaacgcat
     7861 tgagggtatc acagcagtac gtgatgagtc aaaccgtgaa ggtgttcgat ttgttattga
     7921 agtcaagcgc gacgcctcag ccaatgttat tctcaataac ctcttcaaaa tgacccaaat
     7981 gcaaaccaat tttggtttca atatgctcgc tatccaaaat ggtataccga aaattttgtc
     8041 tcttcgtcag attttggatg cttatatcga gcaccaaaaa gaagtggttg ttcgtcgtac
     8101 acgttttgat aaggaaaaag cggaagcgcg cgctcatatc ttagaaggtc tcttgattgc
     8161 gctagaccat atcgacgaag tgattcgtat catccgtgct agtgaaacgg atgcggaagc
     8221 tcaagctgag ttgatgagca agtttaagct ttctgaacgt caaagtcaag ctatccttga
     8281 tatgcgtctt cgtcgtttga caggtttgga acgcgataag attcaatctg agtatgatga
     8341 cctcttggct ctgattgcgg atttagcaga tattcttgct aagcctgaac gtgtttctca
     8401 aattatcaaa gacgaattgg atgaagttaa acgtaaattt tctgataaac gccgtacaga
     8461 gttgatggtt ggacagatct tgagtctcga ggatgaggac ttgattgaag aatcggatgt
     8521 cttgattacc ctttctaaca gaggctacat taagcgtttg gatcaggacg agttcactgc
     8581 tcaaaaacgt gggggtcgtg gtgtccaagg aacgggagtg aaagatgatg actttgttcg
     8641 tgagttagtg tcaactagca cccatgatca tctgctcttc ttcacaaaca agggacgtgt
     8701 ctatcgtctt aaaggttatg aaattcctga gtatggtcgg actgccaaag ggctaccagt
     8761 agtcaatctc ttgaaattgg atgaagatga aagtattcag acggttatca atgttgagtc
     8821 tgatcgcagt gatgatgctt atctcttctt tacaacccgt cacggtattg tgaagagaac
     8881 tagtgttaag gagtttgcca atattcgtca aaatggtctc aaagcgctga atttaaagga
     8941 tgaagatgag ttaatcaatg tcttgttgac agaaggagat atggatatta tcattggtac
     9001 caagtttggt tatgcagttc gctttaatca atcagccgtt cgtggtatga gccgtatcgc
     9061 cactggtgtg aaaggtgtta accttcgtga aggagacaca gttgttggtg ccagcttgat
     9121 tactgatcaa gatgaggttc ttattatcac agaaaaagga tatggtaagc gtacagtcgc
     9181 tactgaatac ccaacaaaag gtcgtggtgg taagggaatg cagacagcta aaattaccga
     9241 aaaaaatggc ttgctggccg gtcttatgac tgttcaaggt gatgaggatt tgatgattat
     9301 cactgataca ggtgtcatga ttcgaaccaa tcttgccaat atttcacaaa caggacgtgc
     9361 aactatggga gttaaagtaa tgcgcctgga tcaagatgct cagatagtga ctttcacaac
     9421 ggttgcggtg gcagaaaaag aagaagttgg gacagaaaac gaaacagaag gtgaagcata
     9481 atgtctcaaa aaaataataa aaagaaaaac aagcgaaaaa atctgctgac aaatatccta
     9541 gcaggatttc tgatattact gtcactggct ttgattttta atactcaaat tcgaaatatt
     9601 ttcatagtct ggaataccaa taagtatcaa gttagccagg tatcaaaaga aaaattagaa
     9661 gaaaatcagg atacagaagg caattttgac tttgattctg tcaaagctat ctcttcggaa
     9721 gctgttctaa cttctcaatg ggatgctcaa aaattaccag ttattggggg aattgcaatt
     9781 cctgaattgg aaatgaattt gccgattttt aaaggacttg ataatgttaa tctcttctac
     9841 ggagctggta caatgaaacg cgagcaagta atgggagaag gaaattatag tctagctagt
     9901 caccatatct ttggtgttga taatgctaat aaaatgttat tttctccttt agataatgct
     9961 aaaaatggca tgaagattta tctaaccgat aaaaataaag tttatactta tgaaatacgt
    10021 gaagtcaaac gtgtgacacc ggatcgtgtt gatgaagttg atgatagaga tggggtcaat
    10081 gaaatcacat tagtaacctg tgaagacctt gctgctacag aacgtattat tgtcaaaggt
    10141 gatttgaaag aaacaaaaga ttattcacaa acatctgatg aaatcctaac agctttcaat
    10201 caaccatata aacaatttta ttaata
//
LOCUS       DAVMCG010000059         9625 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVMCG010000059 DAVMCG010000000
VERSION     DAVMCG010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9625
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.060"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VYP66_001890"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VYP66_001890"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1851387.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VYP66_001891"
     CDS             1085..2809
                     /locus_tag="VYP66_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851388.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            2811..4562
                     /locus_tag="VYP66_001892"
     CDS             2811..4562
                     /locus_tag="VYP66_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851389.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            4954..6213
                     /locus_tag="VYP66_001893"
     CDS             4954..6213
                     /locus_tag="VYP66_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1851390.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6289..6424
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6463..6963
                     /locus_tag="VYP66_001894"
     CDS             6463..6963
                     /locus_tag="VYP66_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1851391.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            7039..7407
                     /gene="rplL"
                     /locus_tag="VYP66_001895"
     CDS             7039..7407
                     /gene="rplL"
                     /locus_tag="VYP66_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1851392.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7608..7781
                     /locus_tag="VYP66_001896"
     CDS             7608..7781
                     /locus_tag="VYP66_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851393.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            7778..8026
                     /locus_tag="VYP66_001897"
                     /pseudo
     CDS             7778..8026
                     /locus_tag="VYP66_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            8016..8363
                     /locus_tag="VYP66_001898"
                     /pseudo
     CDS             8016..8363
                     /locus_tag="VYP66_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8356..8736
                     /locus_tag="VYP66_001899"
     CDS             8356..8736
                     /locus_tag="VYP66_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1851394.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIGLPFVVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            8749..8982
                     /locus_tag="VYP66_001900"
     CDS             8749..8982
                     /locus_tag="VYP66_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1851395.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQILDLDYEDLFRR"
     gene            8985..9572
                     /locus_tag="VYP66_001901"
     CDS             8985..9572
                     /locus_tag="VYP66_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1851396.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQVLYGASLFS
                     FLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLCFSLIHAQGSTNQTNLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT         2854 a         1821 c         2063 g         2887 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gcccaaggac agcagagacc gtctgacaac ttctagtttg gtcactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcttg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tttctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttctggt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tgctcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgttg atcaattccc tcaaccagtc
     1981 ctatatctca gtcaagcgaa tcgaggaagt ctttgttgag gctccagagg atatccattc
     2041 agagttagaa caaaagcaag ctaccagaga taaggtttta caagtccaag aattgacctt
     2101 tacctatcct gatgcggccc agccttctct gagatacatt tcctttgata tgactcaagg
     2161 acaaattcta ggtatcatcg ggggaactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taaaggaacc attcgttcca acttgactct aggtttcaat caagaagtat ctgaccagga
     2401 actctggcag gccttggaga ttgcgcaagc taaggatttt gtcagtgaaa aggaaggact
     2461 cttggatgct ctagttgagg caggggggcg aaatttctca ggtggacaaa aacaaagatt
     2521 gtctatcgcc cgagcagtct tgcgccaagc tccgtttctc atcctagatg atgcaacctc
     2581 ggcactggat accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 cacgagctta attttgatct ctcaacgaac ctcaacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 ccaagtctat tgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag ccgtagattt agcaagccat cctttcctcc
     2881 ttttcctagc ctttctagga actattgctc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgggagcga atcatccata
     3121 agctccatcg tttaccgatt gcctttgtag ataggcaagg tagtggagag atggttagtc
     3181 gtgtaaccac ggacatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggtcagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agaaatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagtcag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcagcctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggagtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga cgaccagtga ccaagttaag ggagctattt
     3841 cctttaaaca tgtctctttt ggctaccatc ctgaaaaaat tttgattaag gacttgtcta
     3901 tcgatattcc agctggtagt aaggtagcca tcgttggtcc gacaggtgct ggaaaatcaa
     3961 ctcttatcaa tctccttatg cgtttttatc ccattagctc gggagatatc ttgctggatg
     4021 ggcaatccat ttatgattat acacgagtat cattgagaca gcagtttggt atggtgcttc
     4081 aagaaacctg gctcacacaa gggaccattc atgataatat tgcctttggc aatcctgaag
     4141 ccagtcgaga gcaagtaatt gctgctgcca aagcagctaa tgcagacttt ttcatccaac
     4201 agttgccaca gggatacgat accaagttgg aaaatgctgg agaatctctc tctgtcggcc
     4261 aagctcagct cttgaccata gcccgagtct ttctggctat tccaaagatt cttatcttag
     4321 acgaggcaac ttcttccatt gatacacgga cagaagtgct ggtacaggat gcctttgcaa
     4381 aactcatgaa gggccgcaca agcttcatca ttgctcaccg tttgtcaacc attcaggatg
     4441 cggatttaat tcttgtctta gtagatggtg atattgttga atatggtaac catcaagaac
     4501 tcatggatag aaagggtaag tattaccaaa tgcaaaaagc tgcggctttt agttctgaat
     4561 aagccattct cttttgaaag tttatggacg aaaaaagttg ccttcgagtg acttttttgt
     4621 tacaatagct agaaaaattg ttcactgtaa tactcaatga aaatcaaaga gcaaactagg
     4681 aagctagccg taggttgctc aaagcacagc tttgaggttg tagataagac tgacgaagtc
     4741 agttcaaaac actgttttga ggttgcagat agaactgacg aagtcagctc aaaacactgt
     4801 tttgaggttg cagatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat
     4861 agaactgacg aagtcagtaa ccacacctac ggcaaagtga atctgaagtg gtttgaagag
     4921 agtacaactt gtcttttaga aaaggagcct ataatgaaag tctttcagca tgtaaatatc
     4981 gtgacttgtg atcaagattt ccatgtttat cttgatggaa tcttagcagt caaggattct
     5041 caaatcgtct atgtcggtca agataagcca gcgtttttag agcaagctga gcagattata
     5101 gactatcagg gagcttggat tatgcctggt ttggtcaatt gtcacaccca ttctgcaatg
     5161 acaggtctga gagggatccg agatgacagc aatctccatg aatggctcaa tgactatatt
     5221 tggccagcag aatctgagtt tactcccgac atgactacca atgcggtcaa agaagccctg
     5281 acagagatgc tccagtcagg aacaacaacc tttaacgata tgtataatcc caatggtgtg
     5341 gatatccagc aaatttatca ggtggtgaaa acttccaaga tgcgttgtta tttttctccg
     5401 actctctttt cttcagagac agaaacaact gctgagacta taagtagaac tcgatccatc
     5461 atagacgaaa tcttaaaata taaaaatcca aatttcaagg ttatggtagc acctcattct
     5521 ccgtatagct gcagtagaga cttgctggaa gcgagtttgg aaatggcaaa agagctaaat
     5581 attccgctcc atgtccatgt ggcggagacc aaggaggagt caggaattat cctcaaacga
     5641 tacggcaaac gcccccttgc ttttcttgaa gaactgggtt atttagatca tccgtccgta
     5701 tttgctcacg gggtcgaatt aaacgagaga gaaattgaac gcttggcatc ttctcaagtg
     5761 gctatcgccc acaatcctat cagtaacctc aaactggcat caggaattgc tccaattatc
     5821 cagctccaaa aagcgggagt agcagtcgga attgcgactg actcggttgc ttccaataac
     5881 aatctagata tgtttgagga aggaaggact gcagctcttc ttcagaagat gaaaagtggg
     5941 gatgccagcc agtttccaat cgaaacagct ctcaaggtac tgacaatcga aggggctaag
     6001 gtccttggaa tggaaaatca gataggaagt ctggaagtcg gcaagcaagc agattttctg
     6061 gtcattcaac cacaagggaa aattcatctc caacctcagg aaaatatgct gtctcacctg
     6121 gtttatgcag ttaaatctag tgatgtagat gatgtttata tcgccggaga acaggttgtt
     6181 aagcaaggtc aagtcctgac agtagaactt taaaagaaaa attacgaaaa attttaaaaa
     6241 aagtttgcaa aaatcttgca ttcttttttt gactatgcta tacttatata cggtttaaaa
     6301 aaactgccta agacagtagg ggagctcgac tcataaatat cctaccgagg acaaaacgta
     6361 tcatgtaaaa agaagcgtat tgtactttcg tgtctaggtt tgggcgcgtt tttctttttg
     6421 aaaaattccc caagcaaaat aattacggag gtgaacacac taatgagtga agcaattatt
     6481 gctaaaaaag cggaactagt tgacgtagta gctgaaaaaa tgaaagctgc tgcatctatc
     6541 gtcgttgtag acgctcgtgg tttgacagtt gagcaagata cagttcttcg tcgtgagctt
     6601 cgtggaagcg aagttgagta taaagttatt aaaaactcaa tcttgcgtcg tgcagctgaa
     6661 aaagctggtc ttgaagatct tgcatctgta tttgttggac catctgcagt agcattttct
     6721 aatgaagatg ttatcgcacc agcgaaaatc ttgaacgact tttctaaaaa cgctgaagca
     6781 cttgaaatta aaggtggtgc aatcgaaggc gctgtcgcat ctaaagaaga gattcttgca
     6841 cttgcaactc ttccaaaccg cgaaggactt ctttctatgc tcctttctgt acttcaagcg
     6901 ccagtgcgca acgttgctct tgcagtcaaa gcggttgcag aaagcaaaga agacgcggct
     6961 taatcttaag ctacacagcg tagcctagct acgaaaaaaa ctattataaa atttaaaact
     7021 tatttggagg aaataacaat ggcattgaac attgaaaaca ttattgctga aattaaagaa
     7081 gcttcaatcc ttgaattgaa cgaccttgta aaagctatcg aagaagaatt tggtgtaact
     7141 gcagctgctc ctgtagctgt tgctgcagct gatgctgctg atgctggtgc tgctaaagat
     7201 tcattcgacg ttgaattgac atctgcaggc gacaaaaaag ttggcgttat caaagttgta
     7261 cgtgaaatca ctggtcttgg tcttaaagaa gctaaagaac ttgttgacgg tgcaccagca
     7321 cttgttaaag aaggcgttgc aactgcagaa gctgaagaaa tcaaagctaa attggaagaa
     7381 gctggagctt cagttactct taaataagag gcatatacca attagaattc ggaatactat
     7441 agtatcagcc ttttagaatc gtgaacacat tttagaaact gataaattaa tttagtttcc
     7501 taccaaaaac cctaccaaaa attctttggc agggtttttc tttttaataa aattattttg
     7561 gagaacagtt gaatattgtt ctcctttttt tattttcagg agggaaaatg acaaaagaat
     7621 tacaatcatc acgctatatt gtcatttcat ttttagtacg tgaaatggga attgatattg
     7681 ttgaagccat ctctcttatg gctgaattag aaaaaagtgg cttggttcga ttggaatcaa
     7741 gtggagattt aatactcaaa gaacttggag gagcgctatg aaacgaatta ccgcaaatca
     7801 ataccaaact tcagaacggt attacaaatt acctaaaatt ctttttgagg atgagaaata
     7861 tatggatatg aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt
     7921 gtctttgagc aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc
     7981 aaatttgatg gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag
     8041 taacattttt agatgattac cataaaaaac acaactaccc actattttac gagccctatt
     8101 ttcaaaacgt tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg
     8161 tagatgatca tcaaaatctt gtttttgttt tatatggaca aggctatcga gccgagggaa
     8221 aagagggaat acttacaacc caagtaactg taaaagctta tgatgaagac aagcaaccga
     8281 ttaacttcgc aaatttatta gattccttaa tcgtctcaga gtatcaaatg gaaccgaatc
     8341 tttgggaggt ctcccatgat tgatctctat ctaagtaaaa atagccaaag aaatcaactt
     8401 cttttagact tcttccaaaa ctatggcatc gaggtatctt gtcattcagt ttctgaaatg
     8461 acaaaggata aattaattga gatgatgagc tattcttcag attgttttga gtttttatct
     8521 cccaatttat tacgatttaa gaaccgtgac aatctaagat taacggattt cgttgagata
     8581 attttaaaaa atcctgaact aaccatcgga cttccttttg tggtttcaaa taagcgggtt
     8641 tatccaagtc tgaatttgga agaggctaga gctctattgc caagagatac gaaacaattg
     8701 atttacatgg cacaaacaca ttatttatct aactaaagga gaagtaatat ggctgaacga
     8761 ttttgggaga acttgtccat tattttggct gaaagaaata tcagctggat tgagttaacc
     8821 agaaaaatgt ttgcgggaga gtttcactat ccaagtgaat tgaatcgttt atatcaaaag
     8881 attcgccact acaagatgga acaacgaatg cctcaaagtc catgggtaga aaggattgtg
     8941 cagatattag atttagatta tgaagattta tttcggaggt aactatgaaa agaataattc
     9001 cagtttatat attccaacaa gtaaatgtcc tattggtatc tctatactta ttgaaatttc
     9061 tttgtatcgg tgagttaact atactacagg ttctctatgg tgcgtctctt ttttcttttt
     9121 tatggatgta tggtcaacga aaacaagtgg tcaaggtcaa tatgaaaact aggatgaaat
     9181 gccttggtat tggactagct agtctactga ttataagtct atgttttagc ctgattcatg
     9241 ctcaaggaag cacgaatcaa acaaatttaa ttggccttca acatcaagtt ccttggtttt
     9301 catttttatt gttcttaatc aatgcgagta tggttgaaga atttctgtat cgtgaaattt
     9361 tatggaactt ggttagaaaa ttagatattc gagttgcttt gacaagtgtt ttatttgcct
     9421 tagtacatca tccaggaacc attctagctt ggtgtctgta cgtttcactt ggaatgtttt
     9481 taggtatggt gcgctataaa tctgacttat ggggaagtat ggggttacat ttggtgtgga
     9541 actttttagt ttatagtttg ctgctttttt aaaataggtg acctgattta tctcataaat
     9601 ctgtagtttt tatgggattc tcttt
//
LOCUS       DAVMCG010000060         9451 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVMCG010000060 DAVMCG010000000
VERSION     DAVMCG010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.061"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            129..1622
                     /locus_tag="VYP66_001902"
     CDS             129..1622
                     /locus_tag="VYP66_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1851397.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2528
                     /locus_tag="VYP66_001903"
     CDS             1635..2528
                     /locus_tag="VYP66_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1851398.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNELVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNHNLLVR"
     gene            2602..5952
                     /locus_tag="VYP66_001904"
     CDS             2602..5952
                     /locus_tag="VYP66_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1851399.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYCATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIEQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISDQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            6223..6468
                     /locus_tag="VYP66_001905"
     CDS             6223..6468
                     /locus_tag="VYP66_001905"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851400.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     SKHGFEVVDETDEVSNHTYGKATLTRIEEIFEEYKSS"
     gene            complement(6562..7032)
                     /locus_tag="VYP66_001906"
     CDS             complement(6562..7032)
                     /locus_tag="VYP66_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1851401.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(7049..9322)
                     /locus_tag="VYP66_001907"
     CDS             complement(7049..9322)
                     /locus_tag="VYP66_001907"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1851402.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         3028 a         1524 c         1992 g         2907 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcca
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt
     1681 acgcttttaa atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc
     1741 gagatgtaga aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc
     1801 ttattaaaaa tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg
     1861 agggggattt agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg
     1921 tagatgaagg ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga
     1981 ccccttttgt tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat
     2041 tgcctaataa actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt
     2101 atgattttcg taaaattcaa tcagaaaaat ttaacgagct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     2221 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     2281 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     2341 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     2401 caacaagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     2461 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcac aatttgcttg
     2521 tgagatagct ataaaagtgt ggagaaatag cttgaaattt agtataatat agctaaacta
     2581 tttgtttaaa gtgagaaaaa aatgggaaat tttagctttc ttttaaaaaa tgacgaatat
     2641 gaatcttttt caaaaccttg cattgaagct gaaaatatga ttgctacatc aactgtggct
     2701 actgccttta tggcgcgtcg tgctttggag caggctgtcc attggatata tagtcacgat
     2761 tcatatttag aagctcccta ttgtgctact ctatcttctt tagtatggga tgatgatttt
     2821 agggatatcg tagattctga actccacaag cagatagttc tgttgattcg gtggggaaac
     2881 catgctgctc atggtggtga aattaaggaa cgagaagcga ttttagcttt acatcatttg
     2941 tatcagtttg ttaattttat cgattattgt tacagcaatg aatttgtgga gcgttatttt
     3001 gatgagaagt gtttaccact ttcagcaaac atcaaatacc gagaaactcc acaatctatg
     3061 ataaagttac aagacagttt accagaactg cctgattttc atgaacagat ggctgctcag
     3121 tccgtagaag ttcaagagac ttatactgaa aaacgtgaga ctgcagcgca acggcaagat
     3181 gtgcctttcc atattgaaca attatctgag gcagagacaa gaaagctctt tattgatatc
     3241 gatctccgtt tagcaggatg gatatttgaa gaaaactgtc gtgttgagat agccgttgat
     3301 ggtctcaagc acggttcagg aattggttac tgtgactatg tactttatgg taaaaatggg
     3361 aaaattttag cgattgtgga ggctaaaaaa gcctctgtca atccagaagt aggggaagta
     3421 caggtcaaag aatatgctga agctttggag aaacatatcg gctatcagcc aatttgcttt
     3481 attacaaatg ggttgaagca ctatatactt gatggtccga accgccgcca gattgcaggc
     3541 ttttactctc aagaagaatt gcaattagtg atggatagac gtcatcttca aaaaccgctt
     3601 gaggatattt ctagtaaaat tagggacgat atttccgggc gtcactacca aaaacatgcc
     3661 attgcaagcg tttgtgaagc tttctctaat catcgtagac aggcactttt ggttatggca
     3721 actggggcgg ggaaaactcg tacagcagtt tctctagttg atatcttatc acgtcataac
     3781 tgggtaaaaa acgttctctt cttagccgat agaacttcct tggttaagca agcctatgat
     3841 tcgtttagaa aattactccc agatctttcc gtttgtaact tcttagaaga taaagaagga
     3901 gctcaatcaa gtcgtatggt cttttcaact tatccgacca tgattggagc gattagtgat
     3961 caagaagaag taaatcaacg cccttttact gttgggcatt ttgaccttat cataattgac
     4021 gaatctcacc gttctattta tcagaaatac aagtccattt ttgattattt tgatgcaagg
     4081 attgtaggct taacagctac tccgcgtcaa gatttagata aaaacaccta tggattcttt
     4141 aatttggaga atggggttcc aacatatgca tatgatttgg aagaggctgt taaagacgga
     4201 tatttagtag cctatcattc tatcgaaacc aaactgaaac tacctacgga tggtctacat
     4261 tatgatgatt tgtccgaaga agaaaaggaa cattttgata gcaaatttga agacgatagc
     4321 tgtgaaaaag atattgatgg gagtgtgttt aattccttta ttttcaataa aagtacagta
     4381 gaaattgttt taaatgaact catgacaaga ggaattcaga cagcctcggg tgatgaaatt
     4441 ggtaaaacta ttatttttgc taaaaatcat gaccatgcgg aatatatcag aggtattttt
     4501 aacaaccgct atcctgaaaa agggagcgac tatgctcagg tgattgatta tagtattaag
     4561 cattatcaga ccttgattga tgattttaaa attaaggaga agtatcctca aattgcgatt
     4621 tctgtcgata tgttagatac aggtattgat gtaccagagg ttgttaattt agtcttcttc
     4681 aagaaagtac gctctaaaac taagttttgg cagatgattg gtcgaggaac ccgtctatgt
     4741 aaagatttat ttggacctga gcaggataag gaaaacttct tggtatttga ttatggggac
     4801 aattttgatt attttcgtgc agatccaaga gatggagagg gtcgtcacat tgtttcgttg
     4861 actcagcgtt tatttaatat caaagtggac ttgattcgag aacttcaggg acttcaatac
     4921 caagaagatc agtttgcgag agcataccgt cagcagcttg tctcggaact tcaaggtcgt
     4981 atagagagct taaatgagtt ggacttcagg gttcgtatgg ttttagatac agtttatagc
     5041 tataggaaat tggaaagttg gcagaatcta actgctgtta caagtgaaac cattcaaaaa
     5101 aatctctctc cgcttttatt tgatgaagat aaagaagatg agatggccag gagatttgat
     5161 ttgtggttgc ttcatattca gttggggcaa ctgacagcta aatcttccac tgttcatatt
     5221 tcccaagtga tgaagacggc tagagctctt tctgctattg gcaatatccc gcaggttttt
     5281 gagcaggctg aaattatcag gaaagtacag gagcctgaat tttggaaaga agttaacttg
     5341 tctgatttgg aaaaaattcg tcttgctatt cgagatttat tacagttttt ggataaaaca
     5401 gaccgtaaac cctactatgt taactttgaa gatcgtatac tctccactgt tcacgagacc
     5461 acagcatttt tgcaggtcaa cgatcttcgg tcttacaatg aaaaagttga gcattatttg
     5521 aaaactcatc tggatgagga gtccatttct aagctatacc ataataaaaa gttgacatct
     5581 gatgatatgc ttgcacttga aaaattgctc tgggaaaaat taggtagtaa agcagactac
     5641 caaagtcatt atgaaaataa ggcaattccg agattggttc gtgagattat tggcttagat
     5701 agagagtctg ccaatcgtat tttttctaaa tttttgtcgg atgagaatct taatgccagg
     5761 cagatttcat ttgtaaaatt gattgtagac tacattgtag aaaatggttt tttagagacg
     5821 aaagtgttaa cgcaagagcc gtttaaatct tatggttctg ttcaactact cttccaacac
     5881 caactaccag tacttcgtaa tattgttcaa atcattgaac ttatcaataa tcgagctgga
     5941 gaagcggctt aaattctaaa gtgattgcca tgctgagact catttaaaat taaaaagagt
     6001 agaaatttat gctatatatg agaagtttta ttaggaagaa tgtcatcgtt ttcctataat
     6061 acagtatcag ttgttaagtg gttgataaat ttcaaagtag atacttgtac cacgatgttt
     6121 gttgatcgag ttattaacaa aagagctact ttgattttaa agaaatagaa aacaaaaagc
     6181 tgagcaagaa ttcaattgca ggagaaaatg aaataatact caatgaaaat caaagagcaa
     6241 actaggaaac tagctgcagg ctgctcaaaa cactgttttg aggttgtaga taagactgac
     6301 gaagtcagct caaaacatgg ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa
     6361 catggttttg aggttgtaga tgaaactgac gaagtcagta accataccta cggcaaggcg
     6421 acgttgacgc ggattgaaga gattttcgaa gagtataaat cttcctagga tagagcaaaa
     6481 cgcatagtat caagggtttt ctgatgttaa agactttcta ccaggttttt taaaagcata
     6541 attgttagtt gtagtcattt attattcttc aaagaaaaat ggtggggcga attttttcag
     6601 ttcttcaaag cacttttgag cagtatctgc atcttcacag atgataagac agacatcatt
     6661 accacaaagg gtagcgatag cgtcagggaa gctcaaagta tcaatgatag aaccaaagga
     6721 ttgagccagt ccaggaaggg tttttagtag gacttggtgt tgaactgggc gcatccagac
     6781 aagggcgtct tccatgtaga gttcgagacg tttttcccat tttgagatgg aaccattgtt
     6841 aagaacataa taagcgctat cttcttcgcg gacttttgat aggttcatat ttttgatgtc
     6901 gcgtgagagg gttgcctggg ttacttgaat gtcgttctca gcaagaaggg cttgcaactc
     6961 agcctgtgta tgaatcttgt tttttgtgat aagagcgcgt ataagttggt ggcggtgttc
     7021 tgatttattc ataataatgt aactcctttt agcaaggtaa ggtaagcatg gactgagcga
     7081 ggtcgacagt caagtggtag tctgtattgt cacggatggt gatttcaaag tcagtagtat
     7141 agaggactaa acggagagtg tctccttctt ttagcttgta aatagttggc tgcagttcaa
     7201 attgaacgtc catccattca tctgcagtaa tatcctctac taacagtaaa tcatttctat
     7261 tttgtaaatt aaggtaacct tttgtcacga ctcgttgtgc ctctggtcta aatggcaatt
     7321 cacagagatt ttccaacatg tgatagcgac cgttatcaat ggttctagca cttaaaatag
     7381 ctggataagg ttgtaggtat ttcttttgcc caaattctag cagttgggca gataagagcc
     7441 ccttgtttgt actggatttg atacgaagat tgagctgagc gcgaccgttt aggtggagat
     7501 ctttagtcac aggaaggtta atagtaatct gattggcttt cccttgatag agctctgtat
     7561 tgaaggtttg gtatgtctta ccatagcgct caaaatcctt atctgggtac tggttttgaa
     7621 tagcttgctc ttcttgacca agtgagaagg tttcacagtt ttcttgccca ccgaagttat
     7681 caagtgataa ccaagtctgt ggagctgtat tgtcctgcca gataacagta ggaagttgaa
     7741 agtctgtttc ctgtcctagt aatttcttgg tcaataaggc atttatggac tcacggaagt
     7801 caattgattg ccaattgttc atgtaaacat gagcaccatt atggaaaaag agatgcttgt
     7861 gtatatgagt aggaagagca tggaacatct ggtaaacatg aagtggtttg acattccaat
     7921 cctgagaacc atgagtaaag acaacctctg cctttacttt atgggcattg agcagataat
     7981 tgcggtcatg ccaaaactga ttgtagtccc cagtttttcg gtctagctga gctttcactt
     8041 tttctaagtc agcttggtga gcttcattgc cacggatata gtcgccagct aagagattac
     8101 gagaataggt taactcagca agggagtcaa agtcctcacc tggataacca cctgggctag
     8161 tcaccagacc gttttcacgg tagtagttgt accatgatga aattcctgcc tcggcaatga
     8221 taacttctaa accatcgact cctgtagtcg caagaccatt ggacatggta cctagatagg
     8281 aaagtcctgt tgtagcaact tttccgtttg accaatcagc cttgacttga cgctggcgcg
     8341 tgtgatcagt aaaggcacgg caacggccgt taagccaatc gatgacattt ttataagcct
     8401 cgatttgctg gtagtctcca ttagtcatga aacctgtcga gtctttggta ccaacacctg
     8461 agacatagag attggcaaag cctctcggaa ggaagtagtc gtttagtgta tagctagagt
     8521 tgatgtgagt tagcttttcc tcagcctctg ctataagctc agctttacct tggggttgga
     8581 cgagatttag ttgaggtttc tctagctcaa tcttgtgagg aagcttaacc tcaagctcgc
     8641 cctccatctt gtagagagcc ttgtcactag ccttgtcatt ggttccctga tgataagggc
     8701 tggctgtcat gatggcaggg atttttccat caaaacgagg gcgaataatg ctaaccttta
     8761 ctaggtctga tagccctttt tggtcagtat cgacacgaga ctcaacgtaa acgacttcac
     8821 gaatgacatc ctggttagaa aaagtagcca aactcttgcc gttaaagtag tggtagtcat
     8881 tatcctccgg aataagacca tcactaacaa gttggtcgat aagagtattt ccttttttgg
     8941 tgcgagtatt gagtaactga tagagatttt caatcaagtc accatatata atgggaaatc
     9001 cagtttcttt acgaaaaacg tcactatctt cgaagtcaac caaataagaa aagcctaaaa
     9061 gttgaaaagc aacagtataa aaaatatctg ctgtcagttc atcttctgat tgaaaaaatg
     9121 tcagcaggtc tgttttttta tcagctgcta ggatagaaag tgggtagttg gtgtcttgat
     9181 aagtgaaaaa gaaacgacgt aaaaaggttt caagtgagtc tttgtgattg gctgtatttt
     9241 gtaaatcaaa gccacatttt tttagttcag ataagacatt ttcttttgga aaattgatat
     9301 aactatattg attaaaacgc atagaacctc catatagaat gacagttaag gttattatat
     9361 caaaaaaaaa gcagaaaggg aattgttaac ttcaaaagga aataatccaa taaaaatgaa
     9421 taaagtacta aattcaatat agagaacaga g
//
LOCUS       DAVMCG010000061         8874 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVMCG010000061 DAVMCG010000000
VERSION     DAVMCG010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.062"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            129..284
                     /locus_tag="VYP66_001908"
                     /pseudo
     CDS             129..284
                     /locus_tag="VYP66_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            484..3759
                     /gene="rexB"
                     /locus_tag="VYP66_001909"
     CDS             484..3759
                     /gene="rexB"
                     /locus_tag="VYP66_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1851403.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3756..7406
                     /gene="addA"
                     /locus_tag="VYP66_001910"
     CDS             3756..7406
                     /gene="addA"
                     /locus_tag="VYP66_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1851404.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVECILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7576..8754
                     /locus_tag="VYP66_001911"
     CDS             7576..8754
                     /locus_tag="VYP66_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851405.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLMFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KNQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLGRLVI
                     "
BASE COUNT         2757 a         1844 c         1882 g         2391 t
ORIGIN      
        1 actatattag attgaaataa gatacgaaca gcttgattag ggaaatcaaa ttaatttcta
       61 gaaatatttt agcatccacg atgtactatt atagtttcaa tttactatag ttcaatcatt
      121 ctatcaagaa tattgaatat ataaaggcac gtaatattaa aacttcttct gatatcgaat
      181 tagagtccga tgttgatggc gataaatcag acaatctacc cgtcgacatt aagatactgg
      241 gacaacacat tgaagtgtat tccgtaccta agaaacaatc ataaaactca aagtcttgtt
      301 accgaggctt ttttattatg tgattttcag tagccagact tattctatct aatacaagta
      361 aagctaagta tttaagattt agcagatgat gaagaaaaga aaggatggcc taaatatttt
      421 aacagattta cgaggctaat catggtataa tatagggtga tgaaaaattc caacgaggct
      481 gagatgaaat tactttatac tgatattcga acttctttga cagaaattct aacaagagag
      541 gcagaagagc tagttgcagc tggcaagcgg gtcttctaca ttgcccccaa ctctctttct
      601 tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc aggcttcttt ttctattacc
      661 gtcacgcgct ttgctcaaat ggctcgttat ctggtcctga atgatttacc agttaaaact
      721 actcttgatg atatcggtct tgggttggcc ttttacaaat gccttgccga actcgatccc
      781 aaggacttgc gtgtttatgg cgctattaag caggatcctc aattgatcca gcagttaatt
      841 gagctttacc atgagatgac caaatctcag atgagttttt tggacttgga gaatttaaca
      901 gatgaggata agaggacgga tttactcttg atttttgaga aagtaacagc ctatcttaat
      961 caaggtcagt tagcccaggg aagtcagttg tcccatttga ttgaggctat tgagaatgac
     1021 aaggtaagta gtgattttaa tcaaatcacc ttggtcattg acggctttac tcgtttttct
     1081 gctgaggaag agcgggttgt ggacttactt cacggcaaag gtgttgagat tgttatcggg
     1141 gcttatgcta gtaagaaagc ctataccagt ccttttagcg agggcaatct ctaccaagcc
     1201 agcgtaaaat ttctccatca tctggcttct aaataccaaa cgcctgctca ggactgttct
     1261 caaactcatg agaagatgga tagttttgac aaggcctctc gtttgttgga gtcttcttat
     1321 gacttttcag aactcgcttt ggatgtcgat gagaaagacc gtgaaaattt acaaatctgg
     1381 tcttgtttga cgcaaaagga ggagttggag ctagtagccc gtagcattcg tcagaaatta
     1441 catgagaact cagacctgag ctacaagcat tttcgtattc tcttggggga tgtagcttct
     1501 taccagttat ctctcaaaac catttttgac cagtatcaga ttccttttta tcttggtaga
     1561 agcgaagcca tggctcatca tcccttgact cagtttgtcg agtctatttt agctttaaaa
     1621 cgttaccgtt ttcgtcagga ggatttgatt aatcttctta gaactgattt gtatactgac
     1681 ctcagtcagt ctgatattga tgcttttgag caatatatcc gctatcttgg tatcaatggc
     1741 ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg gaaaatttaa tcttgagcgt
     1801 ttgaatgtcc tccgcctgag aattttagca cctcttgaaa ccctctttgc cagccgaaaa
     1861 caaaaggctg aaaacctcct acaaaaatgg agtgtctttc taaaagaagg agctgtgacc
     1921 aagcagttac aagatttgac aaccactttg gaagctgtag aacaggaaag acaagccgaa
     1981 gtttggaagg ctttctgcca tgttttagaa caatttgcga ctgtttttgc tggttcacag
     2041 gttagtctgg aagacttcct agccttgctc cattctggaa tgagtttgtc ccaataccgt
     2101 accattccag caacagtgga cactgttctg gtgcagagtt acgatttgat tgcaccattg
     2161 actgctgact ttgtctatgc tattggacta actcaggaca atttaccaaa aatttctcaa
     2221 aacaccagtc ttctgacaga tgaagaaagg caaaatctaa accaagcgac cgaagaaggc
     2281 gttcaattac tgattgccag cagtgaaaat ctcaagaaaa atcgctacac tatgctttcc
     2341 ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc caagcctttt taacgaaagt
     2401 gaaagtaagg aatctgccta tcttcaagag ttgatccatt ttggatttag gcggagagag
     2461 aagaggatga atcacaaagg actgtctaag gaggatatgg ggtcctatca cagtcttttg
     2521 tctagtctgg ttgcctatca ccagcagggt gagatgagcg atactgagca agatttgact
     2581 tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag atctgcaagg tctggaaaat
     2641 ccagctatcc caaccagtcc aagcagcaag accttagcca aggacacctt gcaagctctc
     2701 tatcctgcca aacaggagtt ttacctgtct acgtcgggtt tgacagagtt ttatcgcaat
     2761 gaatacagtt atttcctacg ctacgtttta ggcttgcagg aggaattacg tttgcgtcct
     2821 gatgcccgta gtcacgggaa tttcttgcat cgtatctttg aacgcgcctt acagttgcct
     2881 aatgaagatt cctttgacca acgtctagaa caagctattc aagaaaccag tcaagaacgc
     2941 gaatttgaag ctatttatca agaaagtttg gaagcccagt ttaccaagga agttttgctt
     3001 gatgttgcac ggacgactgg acatattctc cgacacaatc cagccatcga aaccatcaaa
     3061 gaagaagcaa attttggtgg aaaagaccaa gcctttattc aattagacaa tggacgcagt
     3121 gtctttgtac gaggcaaggt ggaccggatt gaccgtttga aagctaatgg agcgatagga
     3181 gtagtagact acaaatccag tctgactcag ttccagtttc ctcatttctt taatgggctc
     3241 aattctcagt taccaaccta tcttgctgcc ctaaaaagag aaggggagca gaactttttc
     3301 ggcgccatgt acttggaaat ggctgaacct gtccaatctc tgatggcggt aaaaagtctg
     3361 gcaggagcag tggtagaagc cagcaaatct atgaaatacc aagggctctt cttggaaaaa
     3421 gaaagcagtt atttaggcga attttataac aaaaacaagg ctaatcaact gacagatgag
     3481 gaatttcagc tcctactgga ctacaatgcc tatctttaca agaaagctgc tgagaagatt
     3541 ttagcaggcc ggttcgccat caatccttat actgaaaatg gcagaagcat tgccccatac
     3601 gtccagcaac atcaggctat tacaggcttt gaagccaatt accatctggg ccaagcccgt
     3661 ttcctagaaa agttggacct agctgatggc aagcgtctgg tcggagaaaa actcaagcaa
     3721 gcttggtttg aaaaaataag agaggagtta aatcgatgaa gcttattccc tttttaagtg
     3781 aggaggagat tcaaaaactg caagaagcag aagcaaattc gagcaaggaa cagaagaaaa
     3841 ctgccgaaca aatcgaagct atctacactt ctggtcagaa tatcctggtc tcagcatcgg
     3901 ctggttctgg aaagaccttt gtcatggtag agtgcattct ggaccaattg gcgcgtggtg
     3961 tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa ggctgcaact gaacttaaag
     4021 aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac agatgatgtc gatctcaaac
     4081 aacacttggg tcgccagttg gcagacctac ccaacgctgc catcggaacc atggactctt
     4141 tcacacaaaa attccttggc aaacatggtt atctgcttga tattgcacct aatttccgta
     4201 ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga agtctttcat gaggtctttg
     4261 aagcgcatta ccaaggtaaa cagaaagaga gctttagtca tttgctgaaa aactttgctg
     4321 ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta taaaatctat gacttcctcc
     4381 aatccaccag taatcctcaa aagtggctga gtgaatcttt cctcaaaggc tttgagaaag
     4441 ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat caaacaagcc ctctgggatt
     4501 tggaaagctt tttccgttac catctggata acgatgccaa ggagtttgca aaggctgcct
     4561 atttagaaaa tgttcagtta attctggatg aaattggctc cctaaatcag gagttcgata
     4621 gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat ctctaaggag aaaaacggtc
     4681 gagctctgac taatgccagc cgtaaggctg atttgaagcc cctggctgat gcctacaacg
     4741 aagagagaaa gacccagttt actaaactag gacaattatc agaccagata gcgattctcg
     4801 actatcaaga acgttatcat ggagacactt ggaaactagc taaaaccttc caatctttca
     4861 tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca ggaaaatgcc tttgaattcg
     4921 ctgatatcag ccattacacc attgagattt tagaaaattt cccacaagtt cgtgagtctt
     4981 atcaggagcg cttccatgaa gtcatggtcg atgagtatca ggatatcaac catattcaag
     5041 aacggatgct ggaattgttg tctaatggcc acaatcgctt tatggtggga gatatcaagc
     5101 aatccatcta tcgtttccgt caggcagacc cgcagatttt caatgagaaa ttccaacgct
     5161 atgcgcaaaa tcctcaagaa ggcaagctca ttctcctcaa ggaaaatttc cgtagtagtt
     5221 cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct catggaccaa gaggtcggcg
     5281 aaatcaacta tgataacatg caccagcttg tttttgccaa taccaaactg actcccaatc
     5341 cagacaacaa ggccgaattt ctcctctacg acaaggacga tacaggtgag gaagaagaga
     5401 gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt tatcaaggag atccttaaac
     5461 ttcatcagga aaaaggtgtt gcctttaagg aaattgccct tctgacctct agtcgtaatc
     5521 gtaatgacca aattctactt gccctgtctg agtacgggat tcctgtcaaa actgacggag
     5581 agcaaaacaa ttatctccaa tccctagaag tgcaagtcat gctagacacc cttcgtgtca
     5641 ttcacaatcc cctgcaagac tacgccttgg ttgcccttat gaagtctcca atgtttggtt
     5701 ttgatgagga tgagctagca cgtttgtccc ttcagaaagc agaggataaa gcccacgaaa
     5761 atctctatga gaaactagtc aatgcacaaa aaaaggcaag tagtcaaaaa ggcttgattc
     5821 acacagctct agctgaaaaa ctaaagcaat tcatggatat cctagcttct tggcgcttgt
     5881 atgccaaacc ccactctctc tatgacttga tttggaagat ttacaacgac cgtttttatt
     5941 atgactatgt tggggctttg ccgaatggtc ctgctaggca ggccaatctc tatgccctag
     6001 cactgcgtgc tgatcaattt gaaaagagca atttcaaagg tttgtcgcgt tttattcgta
     6061 tgattgacca agtcttagaa gcccagcacg atttggcaag cgtggccgtc gcaccgccaa
     6121 aagatgcagt agagctcatg accatccaca agagtaaagg gctggagttt ccttacgtct
     6181 ttatcctcaa tatggatcaa gatttcaaca aacaagactc tatgtcagaa gtcattctca
     6241 gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat ggagacaggg gcagtagaag
     6301 accactatcc taaaaccatc aaactctcca ttcctagtct gacctatagg cagaacgaag
     6361 aggaattaca gctagcaagc tattctgagc agatgcgttt gctgtatgtt gctatgacgc
     6421 gggctgagaa aaagctctat cttgtcggca agggttctcg tgaaaagctg gaatccaagg
     6481 aatacccagc agccaaaaat gggaaactaa atagcaatac tagactgcaa gcacggaatt
     6541 tccaagattg gctttgggct atcagtaaag tgtttactaa ggacaagctc aactttagtt
     6601 atcgttttat tggcgaagat cagttgacca gagaagctat cggagagttg gaaaccaaga
     6661 gtcctctcca agatagctcc caagcagaca atcgtcagtc agataccatc aaagaagctc
     6721 tggaaatgct gaaggaggtg gaagtttata atactcttca ccgcgcagct attgaacttc
     6781 ctagtgttca aaccccaagt caaatcaaga aattctacga accagttatg gatatggaag
     6841 gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa aatcagcttc gatttgccag
     6901 atttttcaac caaagaaaag gtaactggag ctgagattgg tagtgctact cacgaactca
     6961 tgcagagaat tgacctcagc cagcaactaa cccttgctag cctaacagaa acactcaaac
     7021 aagttcaaac tagccaagct gtcagagaca agatcaatct tgataaaatt cttgctttct
     7081 ttgacacagc actcggtcag gaaatttttg ctaataccga ccatctctat cgcgagcaac
     7141 ctttctccat gctcaaacga gaccaaaaga gtcaggaaga ctttgttgtc cgtggtatcc
     7201 ttgatggcta tctgctttac gaaaacaaaa ttgttttgtt cgactacaag acagaccgct
     7261 atgatgaacc aagtcaactc gtagaccgct atcgtggtca gttagctcta tacgaagagg
     7321 ctttatcacg agcctattcg attgaaaata ttgaaaaata cttgatttta ctcggtaaag
     7381 acgaggttca agttgtaaaa gtataactta tactcttcga aaatctcttc aaaccacgtc
     7441 agcttcgcct tgctgtatat atggttactg acttcgtcag ttctatccac aacctcaaaa
     7501 cagtgttttg agctgactgc ggctagcttt ctagtttgct ctttgatttt tattgagtat
     7561 tagaaaggag acctcatgac acttccagtt agaaaatccc tgcacgatgc agttttacag
     7621 gcttcgaaag cggatacttg ggaacaagct accaaggaat ggaatgaagt ttccttgatg
     7681 tttaacggta tcggccgtag caattgtgtc tgtggaaatg ccatcaaata cgcttatgaa
     7741 ctctttaacg gtgtcacagg ccaacgcctc tttccaattg gtagcgactg tgttcgtcat
     7801 tttcatcgat tgtcccttga ccagcaattg gaagaggaag aaaaactgct cagaaaggtt
     7861 gaaaatctaa ccagaaaagc tcagaaaaag gaaaaaatca aggtcaataa aagtgacttt
     7921 gacgagcgac ttctaaaatg gctctgggaa aaaggtgttt tcaaacccaa tcgtggcaat
     7981 caatttgcgc ctgagagaga ctaccagctt ttcctagaag tctttcaggg aggaagttgg
     8041 accaaggcgg aaccaaagaa aaaggctcgg atggaagaag tccttgaaaa gtgtatcaaa
     8101 ccatttttac ttgggaaatc ggatgaccaa ctctaccttg tcaagctagg caaggagaaa
     8161 attgactacg aacaagaact ccgtatccag gcagagaaag aacgcaagaa gagggataaa
     8221 atcgccaagc aatatgcaga taatctggtt ctagccatgg gacccgcaga gcgtgcttat
     8281 caagattact ttggctttac agagaccctg actcaagaag aacgcaagtg ggaaaaaatt
     8341 ctttttggta aaaatagagc agaacgggct atcaaggcca aacaatacca aaaagagctg
     8401 gaaaaaaacc aacgaattgc cagtcaggat ccaattgaaa gaaaacagaa gcagacttgg
     8461 ctcctcaatt cctattttcg agagcttcct gaagaaaaag ctcgattttc taggctctta
     8521 ttagaatatc gaaaaagtgg tgaagtaccc ttttcaactg aatacctgtc agatcatctc
     8581 atcgactttt tctataaaat gaaagccttt gaatttgaaa tcgcaccaga acaagtccga
     8641 gattttctaa aaaaaagcct gcaggaagac catcgctcat cagcacaagg aagctggata
     8701 gaaggaattc tcctcaactg cctcaaacca tttttaggac gattagtgat atgagtaaca
     8761 cctaccgtgt aaatttcatg gtaggtgtta ttgtacccca aaataatata aaacaaagta
     8821 tgaaagcgca tctcaatttt aagacttttt tgtaaattaa gagtataatt aagg
//
LOCUS       DAVMCG010000062         8450 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVMCG010000062 DAVMCG010000000
VERSION     DAVMCG010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8450
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.063"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..347
                     /locus_tag="VYP66_001912"
     CDS             <1..347
                     /locus_tag="VYP66_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEV1851406.1"
                     /translation="KNLQILQNNEILKKIISEIKILHEVIGLHMNRAISCYREEQSGC
                     LDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNISEVISALDIIHHLDKIAHTTQAIY
                     KWIMYRKYGNIN"
     gene            360..1835
                     /gene="galT"
                     /locus_tag="VYP66_001913"
     CDS             360..1835
                     /gene="galT"
                     /locus_tag="VYP66_001913"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1851407.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1848..2858
                     /gene="galE"
                     /locus_tag="VYP66_001914"
     CDS             1848..2858
                     /gene="galE"
                     /locus_tag="VYP66_001914"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1851408.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNTFE
                     SVNKIPIPYKIVPRRSGDVATCYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            3038..3697
                     /locus_tag="VYP66_001915"
     CDS             3038..3697
                     /locus_tag="VYP66_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1851409.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3722..4789
                     /locus_tag="VYP66_001916"
     CDS             3722..4789
                     /locus_tag="VYP66_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1851410.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDAKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4893..5903
                     /locus_tag="VYP66_001917"
     CDS             4893..5903
                     /locus_tag="VYP66_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851411.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDEIVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5915..7606
                     /locus_tag="VYP66_001918"
     CDS             5915..7606
                     /locus_tag="VYP66_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1851412.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7609..8319
                     /locus_tag="VYP66_001919"
     CDS             7609..8319
                     /locus_tag="VYP66_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1851413.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2878 a         1159 c         1659 g         2754 t
ORIGIN      
        1 taaaaaatct acagattctt caaaataatg aaattttgaa gaaaattatt tcagaaataa
       61 aaatacttca tgaagttatc ggactgcata tgaatagggc tatatcttgt tatagagagg
      121 aacaatctgg atgtttagat atggttgtta tacaaaaaca gaatgagata gaagagctta
      181 gtataaatat ggaaaagaaa ataatgaatt acatatttga agatgatggg aacatttctg
      241 aagtaattag tgctttagat attattcatc accttgataa aattgctcat actacgcaag
      301 caatttataa atggataatg tatagaaaat atgggaacat aaattagaaa gaaaaatata
      361 tgaaaacaat tattgataat tttgttgata gagtaattga atacggaatg tataatgaaa
      421 ttgacaaaat atatgtgaaa aatagagtac tagcgttaat aggtgaggag ggaattgatc
      481 gcatttccga tgaaaatgac ctgaaacaaa taaaagatta cttagtggaa atcgccttaa
      541 aaaacggtaa aattaaagat ttaatcgagg aaaaggaatg tttaggagca gagttaatga
      601 atttcatagt tcctttacct agtcgattaa atgatatttt ttggagttca tatgatatat
      661 ctcctcaaga agcagttgaa gagttttata agttaagtaa agatagtgat tatattaaaa
      721 cttctgctat tgctaagaat attgagtttc gagcatcaac taaatacgga gagctagaga
      781 ttacgataaa tttgtcaaaa cccgaaaaag atccaaaaac aattgctgct gaaaaattag
      841 taaaagcaac taattatccc aaatgtttac tatgtatgga aaatgaagga tatcaggggc
      901 gaataaatta tccagcacgt tcgaatcata gaattattcg gttgaaactt ggtgacgaag
      961 tatggggatt ccagtattct ccctactcat actttaatga gcatgcgata tttttgaata
     1021 gtcaacatgt accaatggct attacctcta aaacatttga acaattattg gagattgttg
     1081 atattttgcc aggatatttt gctggttcaa attctgatct tcctatctca ggaggctcca
     1141 ttcttagtca taaccactac cagggaggga aacatatttt cccaatggaa aaagcaaaat
     1201 ttgagagtga attttgtttt aaagactttg aggatgttaa tgctggtatt gtaaaatggc
     1261 caatgtcagt aattaggtta caaagtgaaa ataaaaatcg cttgttagat ttagctacta
     1321 aaattctaaa taagtggaga gaatattcag atttagaagt agacatcatt gctatgactg
     1381 aagatgtccc acaccatacg gtgactccta ttgctcgtaa agtggacggg agatacgaat
     1441 tagatattgt tctaagagat aatcatacta ctgaacaata cccagatggt gttttccatc
     1501 ctcatcaaga tgtacaacat attaaaaagg aaaatatcgg gttaatcgaa gtgatgggac
     1561 ttgcgatatt accacctcgt ttgaaaccag agttagaaga agttggaaaa tatcttttag
     1621 gagaggataa tgcaattgcg gattatcatt tagaatgggc cgaccaattg aaagaaaaat
     1681 atcctcgcat taataaagaa gaggttaata gcgtagttca acacgaagca ggacaagtgt
     1741 ttgcgagagt tctggaagat gcaggagttt ataagaatac accgtctggg catgaagcgt
     1801 ttatgagatt tgttaagtcg gttggaatta attaggagga aacccagatg gcaatattgg
     1861 taacaggcgg agctggttat attggtagcc ataccgtagt agaattacta aatttaggaa
     1921 aggaagttat cattgtcgac aacctttcga actctagcaa attggtgcta gaccgtattg
     1981 aagcaattac aggaatacgt cccgtgtttt acgaattaga tgtttgtgat aaacaagcat
     2041 tgagaaaggt atttgaacaa gaatcgattg atgctgcaat tcattttgca ggttataaag
     2101 ctgtcggaga atccgtgcaa aagcctgtga tgtactacaa aaataatatt atgagtacat
     2161 tggcacttgt tgaagtgatg tcagaattta atgttaaaaa gattgtcttt tcttcaagtg
     2221 cgactgtata tggaattaac aatcagtcac ctctaattga gacgatgcaa acaagtgcga
     2281 caaatcctta tgggtatacg aaagtgatgc ttgagcaaat tttaaaagat gttcatgtgg
     2341 cagattcaga atggagtatt gcgttgcttc gttatttcaa tccaattggt gctcatgagt
     2401 ctggtttgat tggggaagat ccctcaggaa ttcctaacaa cttgatgcct tatattgcac
     2461 aagtagcggt aggtaagcta tcagagctaa gtgtgttcgg aaatgattat gatacgcttg
     2521 atggtactgg tgtgcgtgat tatatccatg tagtagattt agcaatagga catataaaag
     2581 ctttagaaaa agtatctgaa aaaacagatg tttatatcta taacctaggc tcgggagaag
     2641 gcactagtgt attacaactt gtaaatacat ttgaaagtgt taataagatc cctattcctt
     2701 ataaaatagt tccaagacgt tcaggagacg ttgcaacttg ttatgcaaat gcagacaaag
     2761 catataagga attaaattgg aggacaacaa aatcgattga agacatgtgt agagatacat
     2821 ggaattggca atcaaaaaat cccaatggct ataattgatg atactgtcta tatgagtgct
     2881 gtattttgaa aaaattactt aaccttttaa tgaaatgcat atttaatgaa agataaattt
     2941 aaaaaaatgt ttgcaagtgc ttgacaaagg aaacggtttc attgtataat gtaaacatga
     3001 tgacaccgat gtcaaatata aaaaagaagg tctttatatg aaaaacttaa caaaaattaa
     3061 gttcaaagag aatggggaat ttaatcattt ccctgggaat acagttgtag caaatcttta
     3121 tactaaacaa gatttgatgg aagttgttga tattattcaa tcacgttata gagaattacc
     3181 atttatcgat aagtttactt taactccaag gaattctatt cacatgactg taattgaatt
     3241 gttgtgccat gaaaatcgtg aaacggagtt ttggagcagt aatcttcctc tagatacacc
     3301 tttacaggaa atacatgatt actttgctaa acaacttgaa atttttccat tgttggatga
     3361 agaaattcat atgcgtataa ctgaaatggg aaaacaaaac atactagttg aacctgcaga
     3421 tgaagcttct gcaaagagat tagaagaaat tcgtacttat gtctcagaaa aagcaggtgt
     3481 ttgtttccct aatcatgata gatatcaatt ccatatttca attgggtatc ttcggattcc
     3541 tctaaccgaa gaggaggaag aagagtttac taaagtcaga gcagaattaa ctgaaatttt
     3601 attagagaag attccaacta ttactgtaaa ccgtattgac tatactgtat ttgaagatat
     3661 gagacaattt gttccatatc acgaaaaatt taaataaaat aataaaaaag gagaacttat
     3721 catgaaaaaa atgaaagttt ggtctactgt acttgcaacg ggagttgctc ttactacact
     3781 tgctgcttgc tctggaggtt caaattctac gactgcttct tcatctgaag aaaaagctga
     3841 taaaagtcaa gaattagtta tctattcgaa ctcagtctca aatggtcgtg gtgattggtt
     3901 aactgctaaa gcaaaagaag ctggttttaa tataaaaatg gttgatatcg ctggcgctca
     3961 attagcagac cgtgttattg ctgagaagaa taatgcagtt gcagatatgg tatttggaat
     4021 tggtgctgtt gactcaaata aaattagaga tcaaaaatta ctagtacagt acaagcctaa
     4081 atggttagat aaaattgatc aatctttatc agataaagat aattattata atcctgtgat
     4141 tgttcaacca ttagttttaa ttggggcgcc tgatgcaaaa gaaatgccta aagattggac
     4201 tgaattaggt agtaagtata aaggtaaata ttcaatttat ggtcttcaag gtggtacagg
     4261 acgggcaatt ctagcaagta tcttagttcg ttaccttgat gaaaaaggag atttaggcgt
     4321 atcagaaaaa ggatgggaag ttgcaaaaga atactttgca aatgcctata ctcttcaaaa
     4381 aggtgaaagc tcagttgtta aagcgttaga taaagaaagc ccaattcaat acggtatgat
     4441 ctggggttct ggagcgttaa ttggacaaaa agaacaaaat gttgaattca aagttatgac
     4501 tcctgagatt ggtgtaccat ttgtaactga acaaactatg gttttaagca ctagtaaaaa
     4561 acaagcgtta gctaaagaat ttattgattg gtttggtcaa tcagaaattc aagtagaata
     4621 tagtaaaaaa tttggatcta ttcctgcaaa taaagatgcc ctaaaagagt tacctgaaga
     4681 tacgaaaaaa tttgttgatc aagtgaaacc acaaaatatt gactgggaag ctgttggaaa
     4741 gcatttggat gaatgggtag aaaaagctga attagaatac gtaaaataag aaataagagt
     4801 tattttttat gtccaagtct ctctattatt tctaaattta aggaagaaat aaagagaggc
     4861 ttttggtttt agtaatagag ggagttagtg agatgattaa atttgataat attcaaatta
     4921 aatatggtga ttttgttgca attgataatc tgaatttaga tatacatgaa ggggaattct
     4981 ttacatttct tgggccttca ggatgtggta aatcaactac tttgagagca ttggtaggtt
     5041 ttttagatcc atcatcagga agtattgaag ttaatggaac agatgtcact catttggaac
     5101 ctgaaaagcg tggaattggt attgtatttc aatcttatgc gctatttcca actatgactg
     5161 tttttgataa tattgcattt ggtttaaaag ttaagaaggt agctccagat gttattaaag
     5221 ctaaagtatc agcagtggca gcaaaaatta agatctctga tcaacagtta cagcgtaatg
     5281 tatcagaatt atctgggggt caacaacaaa gggtagcatt ggctcgtgct ctggttcttg
     5341 aacctaaaat tctttgtcta gatgaaccat tgtcaaacct tgacgcaaaa ttacgtgtag
     5401 atttgagaaa agagttgaaa agacttcaaa aagagttagg tattactact ttatatgtta
     5461 ctcatgatca agaggaagcc ttgactttat ctgatagaat tgcagtcttt aacaatggat
     5521 acatcgaaca ggtcggtaca ccagtagaga tttatcataa ttctcaaact gaatttgtat
     5581 gtgattttat tggagatatt aatgttttga ccgatgaaat agtccacgaa gtattattga
     5641 aaaatacaag cgttttctta gaggataaaa aaggatacat tcgattagag aaagttcgat
     5701 tcaatcgtga aactgaacaa gattttattc taaaagggac aattattgat gttgagtttt
     5761 ctggagttac aattcactat acaataaaag tttctgaaag tcagattctt aatgtaacaa
     5821 gtattgatag tcaggctgct attagatctg tcggagaaag tgtggaatta tttatcacac
     5881 catcagacgt tctgcaattt taaggaggtg cagtatgcgt cataaattaa atttaaaaga
     5941 ttggcttatt cgtttagggt taatctggtt cttagtaaca tttattattt atccaaactt
     6001 tgatctagta gtgaatgtat ttgtaaaagg aggagaattt tcccttgatg ctgtacatcg
     6061 tgttctaaaa tctcagaggg cacttcagag tattatgaac agttttaagt tagcattttc
     6121 actcattatt acagttaatg tcgtaggtat tctttgtgtt ctatttacag agtactttga
     6181 tattaaaggt gctaaaattt taaaattagg ttatatgacc tctttaattt atggaggagt
     6241 ggttttagcg actggatata aatttgtcta tggtccttat ggattgatta caaaattttt
     6301 acaaaatgtt atcccttctt tagactctaa ctggtttatt gggtatggtg cagtcttatt
     6361 cattatgaca ttttcaggaa ctgctaatca tacattgttt ttaacaaata caattcgaag
     6421 cgttgactat cacactattg aggctgctcg aaatatggga gcaaaaccat ttactgtttt
     6481 ccgaaaagta gtgttaccaa ccttaattcc aactctattt gcacttacta ttatggtttt
     6541 tcttagtggt ttatctgcag tagcagcacc catgattgtt ggtggtaaag aatttcaaac
     6601 tataaatcca atgattatta catttgcagg gatggggaat tctcgtgatt tagctgccct
     6661 acttgcaatt attttaggta ttgcaactac aattttgctt actatcatga ataagataga
     6721 aaaaggtgga aattatattt ctatctctaa gactaaagcg cctcttaaaa aacaaaaaat
     6781 tgcgtctaag ccttggaata tcattgctca cattgtagca tatggattgt tcacagtttt
     6841 catgcttcca ctaattttta tagtattata ctcatttaca gatccagttg caattcaaac
     6901 aggtaactta acattatcaa actttacttt agaaaattat cgcttattct ttagtaatag
     6961 tgcggcattc tctccattct tggtcagctt tatttattct attattgctg cgacaacagc
     7021 aacaattctc gcagttgtat ttgctcgtgt tgtcagaaaa cataaatctc gttttgattt
     7081 cttatttgaa tatggtgctc tacttccttg gttactacca agtacacttt tagcagtaag
     7141 tttattattt acttttaatc agccacaatt tcttgtcttg aatcagattt tggtaggtag
     7201 tttggtaatt ctacttattg catatatagt tgtaaaaatc ccattttctt atagaatggt
     7261 acgtgctatt ttatttagtg ttgatgatga gatggaagat gcagcaagaa gtatgggtgc
     7321 ttcacctttt tatactatga tgaaggttat cattccattt attttaccgg ttgttctctc
     7381 tgttattgct ttaaacttta actctttatt aactgacttc gacttatctg tattccttta
     7441 ccatccccta gctcaaccat taggtattac gattcgatct gcaggtgatg aaacagcaac
     7501 atctaatgca caagctctgg tatttgttta tacaattgtt ctgatgatta tttctggaac
     7561 ggtattatac ttcacacaaa gaccggggcg taaagtaagg aaataatcat gacagccact
     7621 agtcttgggt tatcaaatat tgaaatagtt gtcaggattg ttttatcagt agtcattggt
     7681 agtataattg gtttagagag agggagcaaa tcccagcctg caggcatccg aacttatagt
     7741 attgtttgtc tagctgcatg tttgattatg atgacgaatg aatacgtatc ttataaattt
     7801 gggacaggag atcctacacg attaggagct caagttatat caggtgtggg ttttctaggc
     7861 gctggaacga ttcttattac agataaaaag aaaattacag gtctgacaac tgcagcaggc
     7921 atttgggctt cggcaggaat tggattagct attggagtag gtttttatga gggagctctt
     7981 ttagtagcca tttctgtttg gggtgtgata tccatgttcc aaccactaaa aaaatatctg
     8041 caaaatcgtt ctaaaatgat tgaattgtat atagtggtta aatctacaga agcctataat
     8101 cgtgtattgg tttattgtgc agaaaatggt atcagaatga ccgattcaag aacagcgttt
     8161 ggagatgtta attctgacag aattgaatac tttgatgttc cggacaaaaa aatagcgtca
     8221 tttattactc tggaattatc aggtagattt gaacatcttc gactgatgga agaaattgct
     8281 aatattgtag gtgttattta tgtcgaagaa attagctgaa atttagtaaa caaagggaca
     8341 gatgtttttg tccttttgct ttttagatgt tttaatcatc taatttttga gtagattttt
     8401 gctcagaggt ttttatgaaa gattataaaa tcaattttga tttaggtaaa
//
LOCUS       DAVMCG010000063         8387 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVMCG010000063 DAVMCG010000000
VERSION     DAVMCG010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.064"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            429..611
                     /locus_tag="VYP66_001920"
                     /pseudo
     CDS             429..611
                     /locus_tag="VYP66_001920"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1223..1507
                     /locus_tag="VYP66_001921"
     CDS             1223..1507
                     /locus_tag="VYP66_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851414.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1500..1738
                     /locus_tag="VYP66_001922"
                     /pseudo
     CDS             1500..1738
                     /locus_tag="VYP66_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1834..2052
                     /locus_tag="VYP66_001923"
     CDS             1834..2052
                     /locus_tag="VYP66_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851415.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2420..4744)
                     /gene="pflB"
                     /locus_tag="VYP66_001924"
     CDS             complement(2420..4744)
                     /gene="pflB"
                     /locus_tag="VYP66_001924"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1851416.1"
                     /translation="MVVKTVVESQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5139..6200
                     /gene="dinB"
                     /locus_tag="VYP66_001925"
     CDS             5139..6200
                     /gene="dinB"
                     /locus_tag="VYP66_001925"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1851417.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSIAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(6347..7192)
                     /locus_tag="VYP66_001926"
     CDS             complement(6347..7192)
                     /locus_tag="VYP66_001926"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1851418.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7448..>8387
                     /locus_tag="VYP66_001927"
     CDS             7448..>8387
                     /locus_tag="VYP66_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV1851419.1"
                     /translation="MLYVGIDVAKNKHDVTALNVRGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGNRLEAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLR"
BASE COUNT         2720 a         1602 c         1567 g         2498 t
ORIGIN      
        1 ttcaagatac atactcctag aataaacttt atatgaaatt ctcatttttg tttttacaat
       61 tctccttagt taaatcttgt ttaatatatg ttttacatat agtatttagc gccacatagt
      121 actgaactct ctccaaaaac ggttattcct ctttgaatag ggcgttatca caagaaaagc
      181 atctccacgt ttcaacttca tatggctcaa aaacaatcaa ttgatgctaa aacctgtacc
      241 tagatgtttc ggttcataaa accatgaaac tgtaaaagtg gatgaaattg atagcgatag
      301 tcaaatcaag aggcatcata actctaaaaa gtcacaatat ataagttcat cctcggaaaa
      361 atatcattct aattgttgaa atgcctacat gaaaagaaac gtcaaatgct catgaaacaa
      421 cgaatacagg tatcaaaact atgacaaaac aagtccctaa atttactaaa gacactgctc
      481 aactttacac ctgtaaatgg ttgttgtata ataaagttac aaagatgtac gaccacactg
      541 ttgtaaatca tagtgttcgc gaatatatta ctgatagcat ttctacaaat acaattgaag
      601 agactggata gactttaaac gaaatatgtc agtgttttgg cattcctagc cttcatatca
      661 tttaaagaat tctatagaca aaatttttcc caatacagac actcgtaaca actgcttcat
      721 ttttctacca acatatttag gaacaggata agatagaaga agattaatcc atagctcagt
      781 tctataccaa tctaagacaa ataagctaaa aaaacgattg ataataagca aatagattcc
      841 aaattttctc tatctgctca ttttaataaa caatactagt gtaactatcc ttccagtcag
      901 aaacttgtca aatcacaccg aaaactcttc taaaatttat ctcgttaggc aatcaagcaa
      961 aaactcgacg atagtacaaa cattatcata cagaattgac tgcctaaatt atatacttta
     1021 gtaaggtttt cggataagaa aaaaggttca ttttacattt ctaaacattc ttttctaaga
     1081 tgaaaaacag aatttttcga ttgtgattta aagcaacaag aagattttca gtatcatcct
     1141 atagatacga gctaattaag aaaaactaca tttttgaata taaactacaa taatataaac
     1201 taaattttat aggaggaaga caatggattg gtacgattat atgatacagg catccaaaca
     1261 atcacaattc aacgcaagcc attggtttcg ctatttgcga aaagttattt ttgaagacta
     1321 ttcttattta acaaaccaag atgtagaaaa gttgctagac tccaaagaac taacccgttt
     1381 tcaaaaaatt agcttgaagt atgcctttca agagcatact ccaactcata aatatgtgat
     1441 ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa ttgatggaga aatacaaaca
     1501 tggataaaat gaaaccggtc ttccaagccc taaataagaa attaattcag gaaaatctga
     1561 ctttaacaat tatggttatg tcttagaata tcatggttta cgtgccacac aagatgttga
     1621 tgctttttat gaccaaaatc agaaaatcaa tgaaattatt gctcgtgtag gaaaacagtt
     1681 taatcttaac atccacgaag agttatggct caacaatcat gttgcaaagc aaatatgaac
     1741 aaacaacctc ccttaagttt atgcgaatcc ttgtactcat ttgagaatct gaccgtttta
     1801 gtagtcccta ttgagtatgt gttaggaatg aagatgatga gtatcagaga gcaggatttg
     1861 caagatattg gtgcaattat taaatacaaa aactttcatt caccattcga tacctttaaa
     1921 tatttaaaag acatgggatt tgatactatt gacctctctg ttctattaga aggttttagt
     1981 tatgcttatg gtatggattg gttagaaaaa ttttttaaag aaaatcaaga taaacttcgc
     2041 gaattttatt aacagtatca aacaagatga ttgtcaatta gccagtcgtc ttgtttttta
     2101 tgatgaaatg aaataaaatc tgaacaaatc gcttagagaa ttccagtcaa tttctagcgc
     2161 tgtttgagac gtttcagtgg actatagtaa aatgaaataa gaataggaca aatcgatcag
     2221 gacagtcaaa tcgatttcta agaatgtttt agaaataaag gtgtactatt ctagtttcaa
     2281 tctattatat ttcagattcg gtccactatt ccttcccaaa aacattgcat attgcgccga
     2341 aggaattgct cagactatcc caagcacaaa accctcagtc gtttgaccga gggttccttt
     2401 ttattattca agaacttgat tagctcaatg catccaaggc gtcatccatt gaaagaactt
     2461 cgtggaagac acgttgtgtc aattcagttt tttgttctgg agtgaggtat ttagtgttta
     2521 cacagtatcc agagatacgt acgataacgt cttcgcctga catgattttt tcgtaaacat
     2581 cgttcaagtc cataacgttc aagttaacgt gttgtccacc gttttcgaag taaccatcaa
     2641 ggattgttac caagttatca acttgttcat cacgagtctt accaagagcg cgaggtgata
     2701 cttgtgtagt caatgagata ccgtcagctg cataactaaa gtcaaggcta gaaagtgagt
     2761 tcaagttttg caaccaacca cctttagctt tgttagatgg gttagcacct ggtgagaaga
     2821 attcaagttt agacaagttc acagaaccat cttcgttgag gtatacacct ttgtgaactg
     2881 gtgagttacc agtttgttta gagtaagcaa cgttagatgt gattgtcaaa agtgatactg
     2941 tagcttctgc gtctttgtat agtttgtggc tacgtagacg agttgtgtaa gcttcgatca
     3001 accattctgc caattcgttt gaacgtgggt catcttcacc ccagcgtggg tagtcaccga
     3061 ttgtttcgta atcgtagatg tagccatctt cgtcacggat tggtttaact gtagcgtatt
     3121 tgatagctga caatgtatca acagtgttag caaatccaca aataccgaat cccatgttgg
     3181 cacgttgttt agttggcaag aaggccattt gaacagcttc gtagttgtac ctatcagtca
     3241 tgtagtggat gatgttcaag gcatctacgt aagtgtcagt caaccagtca agagattttt
     3301 caaagttcgc tttaactgat tcgaattcaa gaacttcgtc acggattggt tcgatatcaa
     3361 atactttgta gtctttgtga acatcgtcgt aaccaccatt caaaccagta agaagggctt
     3421 taagaacgtt tacacgagca ccgaagtact ggatgttgtg gcgttgttct tcattttctg
     3481 gatcaagtgg agacacacag catgagatac agctcatttc accatatccg tctttagcca
     3541 ttgttgttac accttcgtat tggatagaag agtgtttgtg gctcatgtgc atacagtagc
     3601 gacggaagtt gtatggcaat ttgtcagtcc aaagaactgt caagtttggt tctggtgagt
     3661 taccgatgtt gtcaagagtg ttcaagaaac ggtagtccat cttagtaaca cggtgacgac
     3721 cgtcgttacc cataccagcc atagaagttg tgataaaggt tgggtcacct gagtacaatt
     3781 ggtcataagc ttttgtacga gcaaatttaa ctgtacgaag tttcataacg aaatcatcaa
     3841 cgaattcttg gatttctgat tcagtaaatg taccacgagc aaggtcacgt tctgcaaaga
     3901 tgtccaatac gattggtaca cgacctagag atgtagcagc accgttaatc acacggcaga
     3961 cagccatgaa agcaatgtta acccattgga ttgcttcttt cacgttcatc gctggtttgc
     4021 gaacatcaac cccgtaaagg tcacccaggc gaacaacttg ttgcaatgct tggtattgaa
     4081 ggtttacttc ttcacgaaga cggattgttt cttcatcgat ttctttgatt gcattccagt
     4141 cgtttacttt ttcttgcatc aagtagtctg caccgtaaag agcaagacgt gcgtaaacac
     4201 cgatgatacg tccgcgtgag tatgcatctg gaagaccagt tacagtgtgt gcatgacgag
     4261 cgcgacgaat atttgaagtg taggcacgga aaataccgtc gttaactgtt gttacatatt
     4321 tagtgaagat ttcgtgaaca gctgggtctg gttcgtatcc attttctttt aaagtagttt
     4381 cagccatacg gataccacct tttggcatga agttcaattt gaagagttca tcattttgga
     4441 taccaaagat aacttcattt tctttgtcga taaatccagc agggatatca gcgatagatg
     4501 ttggacgagt gtccattggg aaacgagttt cttcgtagtg tgctttagtt tcttctacaa
     4561 ttttcttgat gtgaagtgaa cgctctgttg gtcctgcaag gaagctttcg tctccatcat
     4621 aaggtgtgta gttagcttgt acaaagcgtg atacacttgc tttttctttc caatctacgc
     4681 ctttgaagcc ttcccaagct ttgtcaaaaa tatcttgtga ttcaacaact gtcttaacaa
     4741 ccatattaat gtcctctttt ttctagtaac agtcatctgt tacattcata agacaagtat
     4801 accataaagt aaccgatttc aacaagtgca aaatccctat ttttacactt tcttttctaa
     4861 aacagtctat attttatttc aaactgtatt atatttttga aaaaaataaa gtcctttttt
     4921 ctttttttca gaaaaaaggg tataataaaa gaaaataagc agtaacactc aatggaaatc
     4981 gaaaagcaaa ctaggaagct agccgcaggc tgctcaaagc actgctttga ggttgtaaat
     5041 agaactgacg aagtcagctc aaaatactgt tttgaggttg cagatggaag ctgacgtggt
     5101 ttgaagagat ttttgaaaag tataaaaagg tgctaggcat gttgattttt cctttgttaa
     5161 atgatttgtc aagaaaaatc atccatattg acatggatgc cttttttgct gcggtggaaa
     5221 tcaaggataa tcctaaactc agaggaaaac ctgtcattat tggaagcgac cctcgacaaa
     5281 caggtgggcg gggagtcgtt tctacctgta gctatgaggc tcgagctttt ggtgtccatt
     5341 ctgccatgag ttccaaggaa gcttatgaac gttgtcccca ggccgtcttt atctcaggaa
     5401 attatgagaa atacaaagct gtgggactcc agattcgagc tatttttaag cgctatacag
     5461 atttgattga acccatgagt attgacgaag cctatttgga tgtgacagaa aataaactcg
     5521 gtatcaagtc agcggtcaaa attgctcgcc tcattcaaaa agatatctgg caagaactcc
     5581 atctaactgc ttctgccggt atttcctata acaagttctt agctaaaatg gcgagtgatt
     5641 atcaaaaacc tcatggtttg acagtgattc tacctgaaca ggctgaggat tttctcaaac
     5701 aaatggatat ttccaaattt catggagtag gaaaaaagac agtagaacgt cttcatcaaa
     5761 tgggcgtttt tactggtgct gatttacttg aagttcctga ggtgacccta atagaccgtt
     5821 ttggtagact aggctatgat ctgtatcgaa aggctcgtgg cattcacaac tctccagtca
     5881 aatccaatcg catccgtaaa tcaatcggca aggagaaaac ctacgggaag attctccgtg
     5941 ctgaggaaga tatcaaaaaa gagctgactc ttctatcaga aaaagtcgct ctcaatctac
     6001 atcaacaaga aaaagctgga aaaattgtca ttttgaaaat ccgctacgag gacttttcaa
     6061 ctcttaccaa acgaaaaagt attgctcaaa aaacacaaga tgctagtcag ataagccaaa
     6121 tagccctgca actctatgaa gaattaagtg agaaagaaag aggtgtccgc ctattgggga
     6181 ttaccatgac tggattttaa agctcaatga aaatcaaaga gcaaactagg aggctagccg
     6241 caggctgctc aaaacactgt tttgaggttg cagataaagc tgacgcggtt tgaagagatt
     6301 ttctaagagt ataaaacctt gaagagttgc cccttcaagg tttttcttat acaaataaac
     6361 ggacaaaact gtaaagtagc aaaacactac caagcacgat acggtattta ccaaaaaggg
     6421 tgaagtcgtg ttttttcaca tagctggtca agaagcgaat agccaccatg ctgaccgcaa
     6481 aagctactcc catcgcgacc aagagtaaaa acaattgccc aaagctcaag agttctccgg
     6541 ctttcacaaa tttgaaaatc tttaaggcac tagctccaaa cataacggga atcccaagat
     6601 agaaggtaaa ttctgtcaca actgaacgac tggttccatt taacaaacca ccgacaatcg
     6661 ttgcacctga acggctagtc cctggtaaaa gagcaagaac ttggaagagt ccgatataga
     6721 aagcggtcgt ataaggaagc ttgtccaact ctgttacact tggctcgata gcacgcgctt
     6781 tattgcgctt ttccaaatat atgaaggcaa ccccgtagat aatcaacatg agagcaactg
     6841 aaaccatgtt atggaagtgg gtatcaaacc aatcatcaaa tttaaagaca ccaagtaaag
     6901 gtaaagtagc aatcaagacc ttcaaccata gtctccaagt cttacgaact tcctgtttgt
     6961 ccttagtcgg tttaaaagga ttgagcttgt taaaataaat caccataact gctaaaatag
     7021 caccaagctg aatcacgaca ttaaacatgg acataaaggc ttcattttga ttttggtatt
     7081 ggataaactc ctctgctaaa atcaagtgac ctgtactgga aatcggcaac cattccgtaa
     7141 ttccttcaac aatcccgaag aagatagatt ttaaaatttc aataagatac atatatttct
     7201 ccttatatta tatttaacgc agttagctac tgccaaagcc caagtggtat acttggaata
     7261 agccactgtg gattagttca tttcctccaa tcgcttgacg atttccgaaa gggtctaaca
     7321 acagcttttt gtttcaattg gtaatgagtt tgataacgca tagacgtttt atctcgtcta
     7381 tggtaacaag gcaaaaagtt cgtggataac caagtagact tgaaatacta tatctggagg
     7441 tactcccatg ctttatgtgg gcattgatgt cgctaaaaat aaacacgatg ttacagcctt
     7501 gaatgttcga ggaaaaactg ttcttaaacc actcactttt tcaaataata aagctggttt
     7561 tgaactctta gatctgtctc ttcgacagct caaccaagac tgtctcatcg ctcttgaaaa
     7621 taccggacat tatgccttta atctactgaa cttcctgcat gaacaaggat ataaagttta
     7681 cacctacact cctttgctca tcaaggaatt tgccaaatca ttatcacttc gcaagactaa
     7741 aacgaataag aaagacgctc atggcatcgc tcttaaactt ctttctgacc ccaatcgtga
     7801 acaatttcaa cacgataatc ggcaagtaga actaaaaata ctggctagac atattcatcg
     7861 tctcaagaaa aaacagtctg attggaaagt acaatacact cgttgtcttg atatcatctt
     7921 tcctgagttg gataaaatcg ttgaaaagca ttcagaatat acctaccaac tcttgacatg
     7981 ctaccctaat cctcagaaaa ggcttgaggc aggatttgat aagctgatag aaattaagcg
     8041 attgaccgct tctaaaattc aggatatcct ctcagttgca cctcgttcta tcggaacaac
     8101 atctcctgct cgtgaattcg aaatcatcaa acattacaag aggctcattg acaaggcgga
     8161 aacatgtgtc aatgacttga tggctgagtt caactcggtc atcacgacgg tcactgggat
     8221 tgggaatcgt ttagaggcgg tcattttagc cgagattcga aatattcatg cctttgataa
     8281 tcctgctcaa ttacaagctt tcgctggact ggattcttct atttatcagt caggtcagat
     8341 tgatttagct ggaagaatga tcaaacgggg ttcccctcat ctgcggt
//
LOCUS       DAVMCG010000064         7185 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVMCG010000064 DAVMCG010000000
VERSION     DAVMCG010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.065"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(662..1654)
                     /locus_tag="VYP66_001928"
     CDS             complement(662..1654)
                     /locus_tag="VYP66_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1851420.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1814..3568
                     /locus_tag="VYP66_001929"
     CDS             1814..3568
                     /locus_tag="VYP66_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851421.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3552..5273
                     /locus_tag="VYP66_001930"
     CDS             3552..5273
                     /locus_tag="VYP66_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851422.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            5284..5868
                     /locus_tag="VYP66_001931"
     CDS             5284..5868
                     /locus_tag="VYP66_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1851423.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            5868..6563
                     /locus_tag="VYP66_001932"
     CDS             5868..6563
                     /locus_tag="VYP66_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1851424.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            6551..>7185
                     /locus_tag="VYP66_001933"
     CDS             6551..>7185
                     /locus_tag="VYP66_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851425.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKVEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFL"
BASE COUNT         2556 a          993 c         1240 g         2396 t
ORIGIN      
        1 actccaaaaa acttgatttt ggagtagtta taaaaactca ttcagataat ttattatttg
       61 attttgatac gattcctgaa aatataatag tagttgacca ttttgaactt acaatcgaaa
      121 aatggttaag taaaagtcaa cagttactat agtttgcaaa ttatttacag aaagaacaaa
      181 aaatgctctg aaacactgat ttcaaagcat tttttgttag tttaaaatta ctcccattct
      241 tcttttccaa acgtacaata tatccaaaac cattcaaaat actagattct attttttata
      301 atatcactaa atccacctaa ttataggacg ttttcagatt tttagtccca gtcccagtac
      361 cggagaaata ttgttttaat ataatatctc tttttgtctt ctaagctctt aaaagcaaaa
      421 gaacaagtaa agagtcaaga caaggataaa aagtccatat tagggcaaat aaaaagcttt
      481 aagacagatg acaaatctaa gtcaaataag aaagaccata gcaaaggtgc agagagataa
      541 atattggcgg tcttcggact gcctttattt ttttatccat ttttcaaatc aaatttattc
      601 agactatata tgcacatata cacttaaatt catataaaaa catggcttgt aaaaaattac
      661 tttaatcaca ataatcgcat ttaaaattgt gatgtttgca agctaaatta cggacttcac
      721 ttggaagttt tcccttgtat cttttataat agatagaaaa tttgctggca gatgaatatc
      781 caacagattc tgctatctct tttataggta gttcagtgtt taaaagaaga gtttcagcta
      841 cattcattct ttttctttga gtgtactctg taatgctttg acaatatttt tccttaaata
      901 aattttttaa tttagtacca ctcattttag atattttttc aagcgtgcct tgatttacat
      961 tcgttgcaaa atgatcatct aagaatcttg ctacatcttc aagtgcttta tcatcatcaa
     1021 tttcaatttt atattttttt ctatttaagt atgtgtcaat tactatactt atccattcat
     1081 ttgcctttgc tttaaagaaa aaatcagcgg caggagcgtc catcttacaa tttaatattt
     1141 ccattgccac tctttctaag gcctttgtaa gtattatttg attcggttga agcaaggttg
     1201 aataaaaaga ttctggatta atgttaatag atgctaaatg tttttctatt agctcttttt
     1261 taaaaccaat ggaaacagca agataacaac aattctcgtg taataaaaaa acaaaatcat
     1321 cttttatatt atcaaaatca aaagtacata gagagtttgc ggtaatagtt tgatacggat
     1381 taaacttttc tccgtttgca ctgacaatgt aacttgaata aattgaaaca tagtctgaca
     1441 tactataagt gctattttga actacttcct ctttgatata aaaatcatgt atatcgataa
     1501 tgaagctgcc tccttcataa aaccaatata gtccttctgc ataagttgaa ttctcttttt
     1561 tccaacaaaa tgtatgacct gcacttgaat acttctcatt gtttttacat tcatctactt
     1621 tcatataatc ttttacaaaa tcataatatg acataacaca ctatcccttt tagacaatat
     1681 tccaattagc cttattaatt caaaactatt gtattagtaa ttataacaga tgtataatag
     1741 aaaagcaatg atagatatta tcaattaagc gaatttatat ctaaaaggga tattaaagaa
     1801 aggagatatg cttatgaaga tttacaaaaa actatttgct tatgtccaag ataagaaata
     1861 tcttggggtt ttggccataa ttttttctgc tatatctgct ctacttacag tatatggata
     1921 ttatttaatc tacaaatttc tagataagtt aataattaat tcaaacttat ccggtgcaga
     1981 gagtatagca ttaaaatctg ttattacact aacaagtgga gcgatatttt attttgtctc
     2041 aggaatgttt tcacatatct tgggatttag gcttgaaaca aatttaagaa aaaggggaat
     2101 cgatggtctg gaaaaagcaa gttttaggtt ctttgactta aatccatctg gtcaaataag
     2161 aaagatcata gatgataatg cagcacaaac tcatcaggtg gtagcacaca tgattcccga
     2221 tagttctcag gcaataatca cacccgtact tgtacttgca cttggcttta tagtaagtat
     2281 aagggttggc ataattttgc ttgctcttac tataattggt ggcttaattt taggggcaat
     2341 gatgggcgag caagaattta tgaagatata ccaagaatcc ctatctaaac taagtgctga
     2401 aactgttgag tacgtgagag gaatgcaagt tgtaaaaata tttaaagcaa atgtagagtc
     2461 ttttaaaagc ttttataagg cgataaaaga ttactcaaag tatgcttatg attattccct
     2521 atcttgtaaa aggccttatg ttttgtatca atggttattt tttggactga ttgcaatttt
     2581 aattattcct atagtttatt ttatgactag cttagctagc gcaaaggtga ttttacttga
     2641 gcttatcatg attttatttt tatcaggagt tctctttgtt tcattcatga gaatgatgtg
     2701 gtactccatg tatatttctc aaggaaatta tgcagtagat actttagagg cgctttacga
     2761 agatatgcaa aaagacaaat tagtgcatgg taatgtcaat aattttaaaa actataatat
     2821 agaatttgag aatgttagct ttgcttataa tgataaagct gtcattgaaa atttatcctt
     2881 taatttagaa gaaggaaagt cctacgcact tgtcggttca tctggatcag gcaaatcaac
     2941 agtagcaaaa cttatatcag gtttttacaa tgttaataaa ggaagcataa agataggcgg
     3001 gatagcaata agtgaatatt ctgacgaagc cttaattaaa gccatttcct ttgtttttca
     3061 agattcaaaa ttattcaaga agagcattta tgataatgta gctttagcta ataaagatgc
     3121 gacgaaagat gacgttatga gagccttaaa attagcagga tgcgatttaa tattagacaa
     3181 attcccagaa agagaaaata caatcatagg ctcaaaaggt gtttatttat ccggtggaga
     3241 aaaacaaaga attgcaattg ctagagcaat tttaaaggat tccaaaatta ttattatgga
     3301 tgaagcatca gcatctattg acccagataa cgagtttgaa ttgcaaaaag cttttaaaaa
     3361 tcttatgaag gataaaacag ttatcatgat tgcacacagg ctatctacaa ttaaagacct
     3421 tgatgaaatt attgtcatgg atagtggaaa aattatagaa agagggtctg acaaagaatt
     3481 aatgtcaaaa gatacaaggt ataagagcct gcaagagatg tttaacagtg cgaatgaatg
     3541 gagggtttca aatgaaagag ttttataaaa aaagatttgc tcttacagat ggaggagcaa
     3601 gaaatttaag taaagcaaca ctggcttcat ttttcgttta ttgtataaac atgcttcctg
     3661 ccatattact tatgattttt gctcaggaag ttttggaaaa tatgggcaaa agcaatggct
     3721 tttatatagt attctcagtt ttgactttga tagcaatgta tattttgctt tctatcgaat
     3781 acgataaatt atataacaca acctatcaag aaagtgcaga tttaagaata aggacagcgg
     3841 agaatttatc aaaattacct ctatcttact tttctaaaca tgacatttcc gacatttcac
     3901 aaacaatcat ggctgatatt gaaggcatag agcatgcaat gagccactca ataccaaagg
     3961 tgggcggcat ggtactgttt ttcccattaa tatctgtaat gatgctagcg ggcaatgtca
     4021 agatgggttt agctgtaatt attccatcta ttttaagctt tatatttata cctttatcta
     4081 aaaaatatca ggttaatgga cagaatagat attatgatgt cttaagaaaa aactcagaaa
     4141 gctttcaaga aaatatcgaa atgcaaatgg agattaaagc atataattta tcgaaggata
     4201 ttaaagatga cttatataaa aaaatggaag atagtgagag agtacactta aaggcggaag
     4261 taactacaat tttaactttg tctatatctt caatatttag ctttatatct cttgctgttg
     4321 tgatatttgt cggcgtaaat ctaattatta ataaagagat aaattctctc taccttatag
     4381 gatatttact agctgctatg aagataaaag actctttaga tgcatctaaa gagggcttga
     4441 tggaaatatt ttatttatcg cccaaaatag aaagattaaa agaaattcaa aatcaagatc
     4501 tacaagaagg cgatgactat agcttaaaaa aatttgatat tgatctaaaa gatgttgagt
     4561 ttgcctacaa taaagacgca aaagttttaa atggtgtaag ttttaaagct aagcagggag
     4621 aggtcactgc tttggtaggt gcaagtggct gcggtaaaac aactatcttg aaacttatat
     4681 caagacttta tgattatgac aagggacaaa tcttaatcga tggcaaagat ataaaagaaa
     4741 tatcaacaga atctcttttt gataaggtct ctatagtttt ccaagatgtg gttctcttta
     4801 atcaaagcgt tatggaaaat attagaatcg gaaagcaaga tgcaagtgac gaagaggtta
     4861 aaagagcagc aaaacttgca aattgcacag attttataga aaaaatggat aaaggtttcg
     4921 atacagttat tggtgagaac ggagctgagc tatcaggagg agaaagacaa agattatcaa
     4981 tagccagagc cttcttaaaa gatgcgccga tattgatctt agatgagata acagcaagcc
     5041 ttgatgttaa caacgagaaa aagattcaag agtctttaaa taatttagtt aaagataaaa
     5101 ctgttgtaat catttcacat agaatgaaat ccatagaaaa tgcagacaag atagtagttc
     5161 ttcaaaacgg aagagtagaa agcgaaggta agcatgaaga gcttttacaa aaatcaaaaa
     5221 tttacaaaaa tttaatagaa aagacaaaaa tggcagaaga atttatttat taggaggact
     5281 acaatggata ataaaaaatt aaaagtaaaa gatttagtaa gcatcggtgt ttttggcgta
     5341 atttattttg ccttcatgtt tggagttggt atgatgggct tgattccaat attgttctta
     5401 atatacccga cagtattagc catagttgca ggaactgttg ttatgttatt tatggctaag
     5461 gttcaaaagc catgggcact atttatattt ggtatgatat caccacttgt gatgtttgca
     5521 gctggtcata cctacgtagt tgtggtttta tcacttatag taatgataat agcagaatta
     5581 attagaaaga ttggtaatta taattcattt aaatacaata tgctttctta tgcaatcttc
     5641 agcacatgga tatgtagctc tttaatgcaa atgcttttag caaaagaaaa atatatggag
     5701 tggtctttga tgacgatggg aaaagattat gttgatgtat tagaaaagtt aataacttat
     5761 cctcacatgg ctttagtagc cttaggtgct ttcttaggag gaattcttgg agcatatata
     5821 ggcaaggctc tattgaaaaa acactttgaa aaagcaggca ttgtataatg cctacttttt
     5881 cttcaaatgc tccctttaat cccaatccga tctctaagat attagtcgta tttatcacag
     5941 gcttaactgt tatgcatagc ataaacatcc gttttgagct ggcaattgtt tgtcttattg
     6001 gtattttgct ttatttgaat ggatacaaaa aaacactttt caaatggatt atattgtgtg
     6061 ggatacttta ctccttgcct aattttatgg tgttatctga attaaaccct atagttaaga
     6121 tgtttttgag tatacctatt gttattagaa tgtttatttt accatttatg gcagcaagct
     6181 ttatgataaa gacctcggat gtaggcgcaa taatttcatc gatggataag cttaagattt
     6241 caaagaatgt atccatacct attgcggtta tgtttagatt cttcccatct tttaaggagg
     6301 agaagaaaaa catcaaaatg gctatgagag taagagggat aaattttaaa aacccagtca
     6361 aatatcttga atatgtttct gtgccactac tcattatatc atctaatata tcagatgaca
     6421 ttgcaaaagc ggcagaaaca aaggcaatag aaaatccaat tgccaagacc agatacattc
     6481 gcgtaaagat acagctaatt gattttgttt atgttttagc ggttgttgga cttattgtgg
     6541 gaggcttaat atggttgaaa taaaaaattt aagtcttgat tatggtgaag agcatatatt
     6601 agatgatata tcactatcca tagccgaggg agagtgcgtg ctatttacag gaaaaagtgg
     6661 aaatggtaag tcatctttaa taaattcaat caatggacta gctgtaaggt atgataacgc
     6721 aaagacaaag gtcgaaataa ttattgatgg taagaatata aaaaatttgg aactttatca
     6781 aatctcaatg cttgtttcaa ctgtttttca aaatcctaag acatattttt ttaatgtcaa
     6841 tacgacatta gaattattat tttatttgga aaatatcggt cttgcaagag aagagatgga
     6901 caggcgtttg aaggatatgc ttgagatatt cccgataaaa aatcttttga acagaaatat
     6961 atttaatcta tccggcggtg aaaaacaaat tctttgcatt gcagcttctt atatagcagg
     7021 tacaaagatt atagttatgg atgagccttc atcgaattta gatattaaaa gcataagtgt
     7081 tttggcaaag atgctaaaga tattaaaaga gaaaggcata agcataattg ttgcagagca
     7141 tagaatttat tatttgatgg acatagttga ccgtgtattt ttaat
//
LOCUS       DAVMCG010000065         6373 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVMCG010000065 DAVMCG010000000
VERSION     DAVMCG010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6373
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.066"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            745..1107
                     /locus_tag="VYP66_001934"
     CDS             745..1107
                     /locus_tag="VYP66_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1851426.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGGVGCNWWNKRDNIAAAAVSGG
                     MSVYQTYAIKKLIANRGMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGA
                     IAYGLDIVDGKFDGYLWA"
     gene            1088..1333
                     /locus_tag="VYP66_001935"
     CDS             1088..1333
                     /locus_tag="VYP66_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851427.1"
                     /translation="MDIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSTSPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            1490..2548
                     /locus_tag="VYP66_001936"
     CDS             1490..2548
                     /locus_tag="VYP66_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851428.1"
                     /translation="MKDDQKYLLAGFYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFMFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYVKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2863..3840
                     /locus_tag="VYP66_001937"
     CDS             2863..3840
                     /locus_tag="VYP66_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851429.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            4217..4591
                     /locus_tag="VYP66_001938"
     CDS             4217..4591
                     /locus_tag="VYP66_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1851430.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAATRYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4799..5701
                     /locus_tag="VYP66_001939"
     CDS             4799..5701
                     /locus_tag="VYP66_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851431.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5757..6110
                     /locus_tag="VYP66_001940"
     CDS             5757..6110
                     /locus_tag="VYP66_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1851432.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            6107..>6373
                     /locus_tag="VYP66_001941"
     CDS             6107..>6373
                     /locus_tag="VYP66_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851433.1"
                     /translation="MSNVDKIRKIHIIVCWGYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVL"
BASE COUNT         2111 a          807 c         1131 g         2324 t
ORIGIN      
        1 tttgggagat atttttattt attttaggtg tgttgttaat tgtaatttca ttactaagtc
       61 ccccaaaaat taaattttgg aaatagagtt agtgagaagg ataggataat agtattatga
      121 tgattgtttt aatttcagtt attgttgcat tcctgtatca taaaattaca gagtatgtca
      181 acaacaggaa aattgatatt gttatttttc tatcattgct gatttctcat tttatttgga
      241 attactattt tttaccaatt gaaatattga tagcaattag ttgagcaaat ttattattaa
      301 gttttttaaa aaaattacag actaaataat attaatctgt gtaatacagt agctcggtca
      361 ttagattcta ttgaagatat aaattaaaaa cgaggttggg aaaaaactca atttgaaaat
      421 gagattgagt aaatctttct atctatataa cgtatatcat caatattttt gaacacctga
      481 taatatgcat ttttcttatt ttaaagattt tttgcctttc ttcatttctt gaatgaatcg
      541 gagagatgac tttatttagg tgtttgacat tactatagat aggatttagc agtactaata
      601 tgaactcata ttataggtgc agacttaaat tttggaagca agctaaagga tatcttatct
      661 aggtaactaa gtgctataaa caaagtcaac gatcacttgt taggaaacta tcctaactat
      721 gcttaataaa aaaggagaaa ataaatggaa ctcgtattac caaataatta tgttgttctt
      781 gagcaagaag agatgatgta tcttgatggg ggtggtgttg gttgtaactg gtggaacaaa
      841 cgtgataata ttgctgcagc tgcagtttct ggagggatgt cagtatacca gacatatgcc
      901 attaaaaagt taattgctaa tcgtggtatg atgagccgag tcgttagaag tgctataaca
      961 agatatattg gtggagttag tatggcaact attactaatg ctcttaatat tgcggctact
     1021 gttgctgaag tcttctcatt aggaggagcc attgcatatg gtttagatat cgtagacggt
     1081 aaatttgatg gatatttatg ggcgtaaaac tatagctatg aaacattttt ttgcaggaat
     1141 tggtgaaatt cattttttgt tatttttatt atatctaagc atgtctacca gtccaattat
     1201 tggactagtg attggatata ctaaaataaa tctaataaat tctattatta tagctcttgg
     1261 tatgatattg gcattaattt tggtattatc aagagtgtat agaaaatatt tttatagaga
     1321 cgatgatgac taaagttttt atcaataatt tgggctcctt gtcaactgta gtgggttgaa
     1381 taaaagctaa cgtctgggga agggtttaaa gctttgcttt atcaaatatt gacttacaga
     1441 gttgctctat tgtattgatg tattcttagt aaataatatg gtgttttgaa tgaaagatga
     1501 tcagaaatat ttattagcgg gattttattc gcttctagtt gcaatatttt attttccatt
     1561 gattgattcc aaggggattt ttgtaagtat attgatggcg gttttacttt tatatttaat
     1621 atacttcatt ggaacagtca ttcatattgt gataattaag tttataagaa aaaaatcttt
     1681 taagtatttg gttctatatc catttactta tgatgggagc tggagatttc aacctataaa
     1741 cttactctac tttccagaaa tggtgagaga tgtcattccg attaatttag ttcaagaata
     1801 ttgccaagga caaccttacg gactgttaaa aaagatgctg aaaagaattc gattgtcacg
     1861 agagatatct ttactcctgg ctaccattat cgtctatttt tttacgcata gaattctacc
     1921 tctttcagta tttacgttca tgttttctta catattgcta tttgcacaat cttatttggg
     1981 tggtaatacc gtttggattg gaaatagaag attaataata gatgatgaat ttgaaaaaat
     2041 cttgctttca aaaagttatg taaaagaaat atcatctgca cgatactcgg aatacttgac
     2101 atgtgaatac aaaaacctta caccaatcat attgttagct atttttgaaa atttgcttga
     2161 ctcctacttg cttcagaatc agagtaaggt tgacttagat attttttata aagttttacc
     2221 tttgctttat aaagaaaaat atactatggg attcaattac tttgtaagtt taaattattt
     2281 actatataag gttggatttt tgggaatcat ttacgataat gaagcattaa gagatttgtc
     2341 aaaacaatat ttaaacaaaa atatttcgga attacaagat ggttctttcg agggcggtat
     2401 acaagatgct gttgcctcta aacaaatagt agttataaat gaatttatag cttgtttaaa
     2461 ttccagatgc gtgccatccc aatatgatag atttttttat aaagatagac cttatatttt
     2521 ttccagaaag agtcctatta aggggtgaaa atttgttaca tttggattaa caagtgtcct
     2581 agggattaga aataactcta gtatagctag atatttttga gtaactagaa atatcattag
     2641 gctacccata tgattgccag aaaagatggc tgatgaatct tatttatact gttgcagtag
     2701 gcattgtcta ggataaataa gctatcttga tgggggagat tggaataatt ttagtagaaa
     2761 cattaaagga ttatggacaa gtagcgcagg attaggtgat gcaatgtgct aagttggctt
     2821 ggtgttagca gtagtattat ttaacaatgg aaagtagact aaatgaaaaa taaacgttat
     2881 ttttttgaca caattttaat aattttactg cttataagca cgatattttg tgtcagccca
     2941 gtatttataa aattggacat cttaggaact ccctctcatg ccatcttaac ctttgtattg
     3001 gcgataccgt tattctatat tttgtctcaa tgcttacata ctttgctatt actagtttcc
     3061 tcaatctttt gtaaattaag accaatttat ttttatttta tatttgtgat cattatagga
     3121 gctaggaaat actatcgaat tctctttcac caactaatgg gatttagtcc aggaatagca
     3181 gtgttttata aggagagtca aacaactaag aatctgttta aattttacta cttcttgtac
     3241 tttacaacac taatttcata ctattttttc tttacttttg tgtatgacaa accgttgctt
     3301 ttgcctctta ttccattttc tattatcata gcattagtac aaaaacttta tagaattgag
     3361 aatcaacaat tatttctgtt aaaatcaaag gtactaacaa tactggaatc taagagggat
     3421 tgtgagttta atcttcagga ttatcatgaa atttggaaat tgcaatcaaa atctgagttg
     3481 ccatgcgtgg ctttatctta tatcagtttg atcaagccat atctttcaga gagcgtgcgt
     3541 gaacaaattg atttattaga agttaagcga tttaaaaaaa taaatcatcc aatatcactt
     3601 tatggtatgt tggatgttat aaaattaaat ctatatttac ggcattataa tgaaaaaaat
     3661 aaatatgaat caatgttaaa taaaatttta gaggtaagac cagactttgt tttaatcgag
     3721 cagaatattg atgatagttt aaatagctcg caaccattat ctttatcttt agccatttca
     3781 gaaatccaac ttttgcttga agtgtatatg gggatcaaac atgtttcaat taggagataa
     3841 aaccagaata atatttgcca ttataggggc aagttgcata ttagtcagta tgtatcttat
     3901 tccacttatt aaaactgaga ataaattttg ggaaatactt ttatttatat taggtgtatt
     3961 gctaattgga attgcgttat taagtcaaaa aaaataaatt ttgaaatagt attagtgagt
     4021 tcgcaatcat ttattgctag tggtttagaa ctgttaagtt tcaaacaata attgatttta
     4081 aaccttaggt aacctataaa aacaaataag gtagagaaag gatatcttat ctaggtagct
     4141 aagtgataaa aacacagtcg tctatcactt gttaggaaac tatcctaact atgcttaata
     4201 aaaaaggaga aaataaatgg aactcgtatt accaaataat tatgttgttc ttgagcaaga
     4261 agagatgatg tatcttgatg ggggattttc tattccgaga tggcctgttg caacagccat
     4321 taatatagct tttaatggtg ttttaggtgg aggagcaatc agtctagtta gaaattatat
     4381 tcgtaattat ggtttgcggc gagttacaag cgcaattgct ggagcagcta caagatatgt
     4441 tggggtacga gttgcaaata gagtggcagg atttgcactg tctgctatta atggatttgc
     4501 agcttggatg tcaattggcg atgctattac aacaatctgg gccaataatg atgtaaatag
     4561 gagagaccca aatttaaacg ccttgtggta actagatatg ggtattaaaa tggaaaaaat
     4621 ttttgttatt attttttttg tatgtctatt tatatcatcc ataacttttt tagcctatga
     4681 ttttgttagc gaagaaataa aaaagttgat tatttggatt aatgtcgttt ttttgatttt
     4741 aatcatagca atgatgattt atccaaaatt aagaaaatga taaggacact gtaaaattat
     4801 gatacgtaaa ctaattgttt tcttactaat gctccctctt tttgtcttgt ggctagagtt
     4861 gcatgtccta gtgaataact tactattgaa tctagaatct ccccttgatt ttgtgattag
     4921 tatgagtctt gctttctgta gtttgatttt atcaaaaata gttttagaca tactatacgc
     4981 attgaaagat ttatacaaga aagaaggtct tattaagatt tttcccttta tttttataag
     5041 aaggaaaaaa gtgaatgtga gattctcgcc ctatttttca ttccatcgta aaagtttgtc
     5101 gcctgatgat ttaagatcta ggattatatg gagttttatt cttgaaattg ctattatcct
     5161 agtatttatt ttaaaaattc cttttgcaat catcatgctt actacaatat ttttctggac
     5221 tataatggat atcaatcatc tcgtttttaa taagacggaa tttcttttta atcaaaacaa
     5281 atggcaaaaa gaagattcat ttgaaagtaa tttgcataag atattgatgg acaaaataca
     5341 aaaatcagaa ttaagctatt ctgacttaat gtcccttctt ctctatgatg cgatgaacca
     5401 atccaccttt ttaacggata gtgaactttt tgaggatatt ttgaaaaaaa tcgaagattc
     5461 tcataacacc cttctgtgta caggtcttgt cgagttactg ctgtatgaga tttctattag
     5521 taacaataac aactggcaag aaaaggttga taaaattaga atacagctca tcagaataaa
     5581 tcaattagat tttttctatt atacaagttg gttaaggcaa aattttgatt tctgtatgaa
     5641 tagagagtat cataaaatga aatctcggaa attattactg agtaataaaa agatagttta
     5701 agttcgtcct atttgtaaaa caaatgaaac aatttcaact aaggaggaga aaacaaatgg
     5761 aacttgtatt accaaataat tatgttgtga ttgatgaaga agtaatgatg tatcttgatg
     5821 ggggagctta tttaagcaag cgtgcttgtc aaggaatttg cgcagcttta gctatgagtt
     5881 caggaacttt tatagcatta gctggagctg cagttttaac caaaaaacta ataaactata
     5941 ttaaggttgg aggtcttgga ggctggctta ttggtgcagc agcaggtgta ttggctacag
     6001 cagcagggaa aatagcttac tgtattggat atggtgttct taatagaggt tgtgatatta
     6061 acgggaaccc ttatccttgg gatggattca tatctgcaac agtaagatga gtaatgtaga
     6121 taagattcga aaaatacaca tcatcgtgtg ttgggggtat atatttttat cattcagggc
     6181 gattataaat gatacggagt attttttgct tattttttta gcttttatct actcaatagt
     6241 atcactacct ctatattctg tgaaaaataa aatagtatct atctgtctag ccataaattc
     6301 gattctgtta atgagttttc ccattttaat caataagttt ttcccagaaa gttttttgac
     6361 ttataccgta tta
//
LOCUS       DAVMCG010000066         6147 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVMCG010000066 DAVMCG010000000
VERSION     DAVMCG010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.067"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            170..370
                     /locus_tag="VYP66_001942"
     CDS             170..370
                     /locus_tag="VYP66_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851434.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATQAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="VYP66_001943"
     CDS             395..811
                     /locus_tag="VYP66_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851435.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="VYP66_001944"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="VYP66_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1851436.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILWDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLTLASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="VYP66_001945"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="VYP66_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1851437.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIS
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2691..4082
                     /locus_tag="VYP66_001946"
     CDS             2691..4082
                     /locus_tag="VYP66_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1851438.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKVPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4225..5142
                     /gene="adcAII"
                     /locus_tag="VYP66_001947"
     CDS             4225..5142
                     /gene="adcAII"
                     /locus_tag="VYP66_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1851439.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5150..>6147
                     /gene="phtD"
                     /locus_tag="VYP66_001948"
     CDS             5150..>6147
                     /gene="phtD"
                     /locus_tag="VYP66_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1851440.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAQAYWNGKQGSRPSSSSSYNANTAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEK"
BASE COUNT         1878 a         1119 c         1300 g         1850 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagc ctatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacgctt gaaagctttg gcaacagtat ctgatccaaa
      301 aatcgatgca acccaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagaataa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaattg atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacctaaa
      841 agacattttc gttcacaaaa gcagtgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttatgggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatgtcatg
     1321 ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggtgcttggc aaggagcgat ttatactctc
     1561 atttacactc tgggcatggc ccttcctttc ttggtcttga cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgtcat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaatttc tgttggaaaa gatgctccag actttacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa cttagctttt
     2401 agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaagt gcacgacaaa
     2521 tagccctaaa acagagtcgt cttagagtaa cttccagttt tgggagagag atggaagtta
     2581 ttttgagaag ttacggtagt cagatttttt tagaaaaaca ttttataaat attcacatat
     2641 ctcctatatt tatggtaaaa tagaattatc agtttatttt ggagtcaaag atgaatatat
     2701 ttagaacaaa gaatgttagt ttagataaaa cagagatgca taggcatttg aagttatggg
     2761 atttgatttt gctgggtatc ggagccatgg tagggacagg cgtctttaca atcacaggta
     2821 ctgcagctgc aacacttgct ggcccagccc tagtgatttc aatcgttatt tctgccttgt
     2881 gtgtgggatt atcagccctc ttttttgcag aatttgcctc gcgagtaccc gctacaggag
     2941 gtgcctatag ttacctctat gctatcttag gagaattccc tgcctggttg gctggttggt
     3001 taaccatgat ggagttcatg acagccatat caggcgtagc ttcgggttgg gcagcttatt
     3061 ttaaaggctt gctctctcaa tatgggatag cccttcctca ggctttaaat ggtaccttta
     3121 atcctcaagc agggacattt gttgatttat tgcctattct tgtcttggtc ttggtgactt
     3181 cgcttgtttt actaaatgcc aaggcagcct tacgctttaa ttcgattcta gttattttga
     3241 aattttccgc tttagctctc tttgttttag taggaatttg gaatattaag tttgataatt
     3301 ggagcaattt tgctccttac ggctttggac aaatctatgg agctagtact ggtattatgg
     3361 ctggtgcgtc cttgatgttc ttcggttttt tgggatttga atccatctct atggctgtag
     3421 atgaagtcaa gactcctcaa aaaaatattc ctagagggat tgtcttatcg ctttctatcg
     3481 taaccattct ctatgccttg gtgacccttg ttttgactgg tgtggttcac tatagtcatt
     3541 taaatgtcga tgatgccgtt gcctttgccc ttcgtagtgt tgggattagt tgggcagcca
     3601 actatgtgtc attagtggct atcttgacct tgattacagt ttgtatttcg atgacctatg
     3661 ccctatcgcg tatgatttac agtttagcac gtgacggctt agtgcctgct gcctttaagg
     3721 aactgacgaa gactagcaag gtaccaaaga atgctactat cttgacaggt ctagcttcag
     3781 cagtagcagc aggaatgttc ccactagcca gtattgcagc ctttttaaat atttgtacct
     3841 tagcctactt gatcatgctg gcttatggtc tgattcgctt acggaaagaa aaaggaatgc
     3901 ccaaagctgg ggaatttaaa acaccattgg tacctctgtt accaatttta tcgatcatca
     3961 tttgtttatc cttcatgtta cagtataata tgaatacctg gattgctttc ctagttgcgt
     4021 tgttagtagg aagtattatt tacttcactt atggctataa gcattctacc atagaagaat
     4081 aaagtgaaag tctattgagt tgttgacact cagcagattt ttatatgtga aagaaatttc
     4141 aaattttttc taaaaatatc ttgacagatt aaattttcag gagtagaata tttactagtt
     4201 aattaaatgg ttaaggagtt gttcatgaag aaacaaaatt tatttttagt cctgttaagt
     4261 gtctttcttt tgtgcttggg ggcttgtggt caaaaggaaa gtcagacagg aaaggggatg
     4321 aaaattgtga ccagttttta tcctatctac gctatggtta aggaagtatc tggtgacttg
     4381 aatgatgttc ggatgattca gtcaagtagt ggtattcact cctttgaacc ttcggcaaat
     4441 gatatcgcag ccatctatga tgcagatgtc tttgtttacc attctcatac actcgaatct
     4501 tgggcaggaa gtctggatcc aaatctaaaa aaatccaaag tgaaggtctt agaggcttct
     4561 gagggaatga ccttggaacg tgtccctgga ctagaggatg tggaagcagg ggatggagtt
     4621 gatgaaaaaa cgctctatga ccctcacaca tggctagatc ctgaaaaagc tggagaagaa
     4681 gcccaaatta tcgctgataa actttcagag gtggatagtg agcataaaga gacttatcaa
     4741 aaaaatgcgc aagcctttat caaaaaagct caggaattga ctaagaaatt ccaaccaaaa
     4801 tttgaaaaag cgactcagaa aacatttgta acacaacata cagccttttc ttatctagcg
     4861 aagagatttg ggcttaatca acttggtatt gcaggtatct ctcctgaaca agaaccaagt
     4921 ccacgacaac taacagaaat tcaggaattt gttaagacct ataaggttaa aacgattttt
     4981 acagaaagta acgcttcttc aaaagtagct gaaactcttg tcaaatcaac aggtgtgggt
     5041 cttaaaactc tgaatccttt agagtcagac ccacaaaatg acaagaccta tttagaaaat
     5101 cttgaagaaa atatgagtat tctagcagaa gaattaaagt gaggaaagaa tgaaaatcaa
     5161 taaaaaatat ctagcaggtt cagtggcagt ccttgcccta agtgtttgtt cctatgaact
     5221 tggacgttac caagctggtc aggataagaa agagtctaat cgagtttctt atatagatgg
     5281 tgatcaggct ggtcaaaagg cagaaaattt gacaccagat gaagtcagta agagagaggg
     5341 gatcaacgcc gaacaaattg ttatcaagat tacggatcaa ggttatgtga cctctcatgg
     5401 agaccattat cattactata atggcaaggt tccttatgat gccatcatca gtgaagaact
     5461 tctcatgaaa gatccgaatt atcagttgaa ggattcagac attgtcaatg aaatcaaggg
     5521 tggctatgtg attaaggtag acggaaaata ctatgtttac cttaaagatg cggcccatgc
     5581 ggacaatatt cggacaaaag aagagattaa acgtcagaag caggaacgca gtcataatca
     5641 caactcaaga gcagataatg ctgttgctgc agccagagcc caaggacgtt atacaacgga
     5701 tgatgggtat atcttcaatg catctgatat cattgaagat acgggcgatg cctatatcgt
     5761 tcctcacggc gaccattacc attacattcc taagaatgag ttatcagcta gcgagttagc
     5821 tgctgcccaa gcctattgga atgggaagca gggatctcgt ccttcttcaa gttctagtta
     5881 taatgcaaat acagctcaac caagattgtc agagaaccac aatctgactg tcactccaac
     5941 ttatcatcaa aatcaagggg aaaacatttc aagcctttta cgtgaattgt atgctaaacc
     6001 cttatcagaa cgccatgtgg aatctgatgg ccttgttttc gacccagcgc aaatcacaag
     6061 tcgaaccgcc aatggtgttg ctgtaccgca cggagaccat tatcacttta ttccttattc
     6121 acaactgtca cctttggaag aaaaatt
//
LOCUS       DAVMCG010000067         6145 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVMCG010000067 DAVMCG010000000
VERSION     DAVMCG010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6145
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.068"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            159..950
                     /locus_tag="VYP66_001949"
     CDS             159..950
                     /locus_tag="VYP66_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851441.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLANLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            966..1694
                     /locus_tag="VYP66_001950"
     CDS             966..1694
                     /locus_tag="VYP66_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1851442.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            2080..2289
                     /locus_tag="VYP66_001951"
     CDS             2080..2289
                     /locus_tag="VYP66_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1851443.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            2279..2767
                     /locus_tag="VYP66_001952"
     CDS             2279..2767
                     /locus_tag="VYP66_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851444.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            2883..4343
                     /locus_tag="VYP66_001953"
     CDS             2883..4343
                     /locus_tag="VYP66_001953"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1851445.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGAQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            4340..5164
                     /gene="nadE"
                     /locus_tag="VYP66_001954"
     CDS             4340..5164
                     /gene="nadE"
                     /locus_tag="VYP66_001954"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1851446.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            5514..6065
                     /locus_tag="VYP66_001955"
     CDS             5514..6065
                     /locus_tag="VYP66_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851447.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWA
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
BASE COUNT         1911 a         1045 c         1312 g         1877 t
ORIGIN      
        1 cattaagtta gatatatgat ataatgttgt taaaaagagg cgcaactttt taaactcaat
       61 aagaatcaaa gagcaaaccg agaatattaa tggaggaata aaaaatgtaa gttataaatg
      121 taagtaagca ttatggtcat tcaatcattc tcaaagatat aaattttgca cttaacaagg
      181 gtgaaattgt tggtctagta gggagaaacg gagttggtaa gagtacattg atgaaaattc
      241 ttgttcagaa taatcaaccg acttcaggga atattataag tagtgataat gttgggtatt
      301 taattgaaga accaaaatta tttttatcta aaacaggttt agagaattta aaatatctgg
      361 caaacttata tggtgttgac tacaatcaag aaagatttag aagtttgatc caagagttag
      421 atttgactca gtctattaat aaaaaagtaa agacctattc tttgggtaca aaacaaaaat
      481 tagctttgct tctaactctc gttacgaaac ctgatatatt gattttagat gaaccgacta
      541 atggtttaga tattgaatca tcacaaatag ttttagcggt tctaaaaaaa ttagctttaa
      601 atgaaaacgt gggaatttta atatcgagtc ataaattaga agacattgaa gaaatttgtg
      661 agagagttct tttcttggag aacgggcttt tgacatttca aaaagtagga aaagatagtc
      721 ataatttctt gtttgagata gctttttcat cagctacaga tagagacatt ttcattacca
      781 aacaagaatt tggggatatt gttcaggaag agggattgag aattactatg tctgggaata
      841 ttcaaagtag tgagcttttt aaatttttta acgaaaactc tattaaagta gttgattttg
      901 aaactaaaaa agagacgctt aaagatattt acctaaatcg ttcaaaataa aggaaggtta
      961 taatcatgaa attaaataaa ttgaattttc ttaaggaaaa tataagaaat ttatattcat
     1021 caggcgtaat atatctcggt ttgcttatct cgtttatacc gccgatattg cttacattct
     1081 ttattctaaa gactcaaggg acatcgcttg gtattaagca tatttcaaac ttttatgcta
     1141 tgctcggtat gttaatggct gttatacatg ctaatcgagt cattagtaga gatttttccc
     1201 acaatacggt aagtttgttt tataatcaac agaagaatcg gatgatttac gtcttgtcta
     1261 attttctata tgccatctca gtttccatta tttatgcttt gaatggcatt gtgttactag
     1321 tcatagtaag taaattgggt attccaggtg atttaggatt agattttata gtagctattg
     1381 tagtcaatac aattttgtta gtcctgtttt attttctatt atcttacatt ttctatttat
     1441 acaaattgaa aagtggcttg gtatttggta ttttagtagc tttactactc tttatcccta
     1501 atatattaaa tacgatgatg atgaatacta gtaatgattt gtttatcaaa gcaattgaac
     1561 ttcttccttt ttattcttta cctgtatttg tggcttcaaa tacgatgtct attagtcagt
     1621 atcttgtggt aatcactaca atcattttat tgtacttttt cactctcaag aaaagcaaga
     1681 agtattcatt ttagtttcat ttagtattat tttgcatacc taaaatacaa taaaaaaatc
     1741 agtcatcttg gtatgctcct gctttcacta ttcaacacgt ttttgactta tactaggctc
     1801 atttccaaaa gcattatata atagtgatat gaaaccaact aaactaaaca agaaatataa
     1861 gcaataaaaa ctcgtttaaa agattctact aaagctaata ctaaataaaa ataaaagagt
     1921 aaactaggaa gtttatttca aacaacctaa aatactgatt ttcggctgaa gataatactg
     1981 gagtgcaaat taatggggtt ataataaata gctgatagct tgtgttggtt ttggattttt
     2041 taagagtaga tgagtattaa aactataagg aggacgaagg tggctaaaaa tttaaaatta
     2101 aaattagctc gggtagagcg tgatttaaca caaggtcaac tggcagaggc tgtcggggtg
     2161 acacgccaga ctattggttt gatagaggcg ggaaaataca atcccagtct ctcgctctgc
     2221 cagtctattt gcagatgttt agggaaaacc ctagaccaac tattttggga ggaagaagat
     2281 gaaaaataga ttttattatt atcaattact agacgaaaga gaagaacaac tgttcaataa
     2341 agcgggatct gaaagtttct atatctgcat tgctttgtcg ctcctatctt atatcatttc
     2401 agtattagca ccaagccttt ttaattctaa tatgctgcta atcgttatca tcatagggac
     2461 attttacttt ttcaatcgcg cccgttatct gggagtgacc tactatagtc gttttcattt
     2521 tacgattttg ggttgttttt tcctaacctt ggctattacg gctcttttga tgttgcagaa
     2581 ttatcaattc aacatagaaa tttatcagca caatcctttg aattttaaat acctgtctgc
     2641 ttgggtcatt acttatgtca tttaccttcc gtgggtcttt attggcaatc ttggtcttaa
     2701 gagctatggc gaatgggctc agaaaaaatt tgaacaagat atggatgaat tggagagtgg
     2761 agaatagctt gttactcttt tctcaatcca gctaaaatgt gatataatag tactaattta
     2821 ttggaataca tgaaagttct tgaaaatttt catgtgtttc tagctaagga agtaggaaaa
     2881 gtatgtatcc agatgatagt ttgacattgc acacggactt gtaccagatc aacatgatgc
     2941 aggtttactt tgaccaaggg attcacaata agaaggcggt ctttgaggtg tatttccgcc
     3001 aacagccttt taagaacggc tatgcggttt ttgcaggttt ggaaagaatt gtgaactatc
     3061 ttgaagactt gcgtttttca gatagtgata tagcctattt ggagtcgctt ggttatcatg
     3121 gggcgttctt ggattacctt cgcaatttca agttggagtt gaccgttcgt tctgcccaag
     3181 aaggggattt ggtttttgct aatgaaccga ttgtgcaggt ggaaggacct ctagcccaat
     3241 gtcagttggt cgaaacggct cttttgaaca tcgtcaacta ccagaccttg gtggcgacga
     3301 aggcagctcg tattcgttcg gttatcgaag atgaaccctt gatggagttt gggacacgtc
     3361 gggctcaaga aatggatgcg gccatctggg gaacacgcgc agcggtgatt ggtggggcca
     3421 atggaaccag caacgtgcgt gcgggtaagc tctttgacat tcctgttttg ggaacccatg
     3481 cccatgcctt ggtacaggtt tatggcaatg actatgaagc tttcaaggct tacgctgcga
     3541 cccacaaaaa ttgtgtcttt cttgtggaca cctatgacac ccttcgcatc ggtgtaccag
     3601 ctgccattca ggtggcgcgt gagctgggtg ctcagattaa ctttatgggt gtgcggattg
     3661 actctgggga tattgcctac atttctaaga aagtccgtca gcaactggac gaggctggat
     3721 ttacagaggc taagatttat gcttctaatg atttggacga aaatactatc ctcaatctca
     3781 agatgcaaaa ggccaagatt gatgtctggg gcgtgggtac caagctgatt acagcttatg
     3841 accagccagc tcttggtgca gtttacaaga ttgttgcaat cgaagatgaa actggtcaga
     3901 tgcgcaatac gattaagctg tctaataatg ctgaaaaagt ttctacgcca ggtaagaagc
     3961 aggtgtggcg cattaccagt cgtgaaaaag gcaagtcaga aggtgactac atcacttatg
     4021 atggtgtgga tattagcgac atgacagaaa tcaagatgtt ccatccgacc tatacataca
     4081 tcaagaagac ggttcgtaat tttgatgccg ttcctctctt ggtggatatc ttcaaagaag
     4141 gaatattagt ttacaacttg cctagtttga ctgacattca ggattatgcc cgtaaggaat
     4201 ttgacaagtt gtgggatgag tataagcgtg tgctcaatcc gcagcactat ccagtggatt
     4261 tggcgcgtga cgtatggcaa gataagatgg acttgattga taagatgcgc aaggaagccc
     4321 ttggtgaagg agaagaagaa tgagtttgca agaaacgatt atccaagagc tgggtgtcaa
     4381 accagtgatt gatgcccagg aagaaatccg tcgttctatt gatttcttaa aaagatatct
     4441 gaaaaaacat cccttcctaa aaacctttgt actagggatt tctgggggac aagactcaac
     4501 cttggcagga cgtttggcgc aattagctat ggaagaactg cgagctgaaa cgggagacga
     4561 tagctacaaa tttatcgctg tccgcctgcc atacggagtg caagctgatg aagcagatgc
     4621 tcaaaaagcc ctagccttca tccagccaga tgtcagcttg gttgtgaata tcaaggaatc
     4681 agctgatgcc atgacagctg cagttgaagc gacaggtagt cctgtttcag acttcaacaa
     4741 ggggaatatc aaggcacgtt gccgtatgat tgctcagtat gcccttgctg gttcccatag
     4801 cggagcggtc attggaacag accacgccgc agaaaatatc acaggtttct ttaccaagtt
     4861 tggtgacggc ggtgcggata ttctccctct ttaccgcctc aataaacgcc aaggaaaaca
     4921 gctcttgcag aaacttggcg cagagccagc cctttatgaa aaaatcccaa cggcagacct
     4981 agaagaagat aaaccaggcc tagctgacga agtcgcactt ggagtcacct acgcagagat
     5041 tgacgactac ctagaaggca aaacaatcag cccagaagct caagcgacca ttgaaaactg
     5101 gtggcacaaa ggccaacaca aacgccactt acccatcacc gtatttgatg acttttggga
     5161 gtaaaaaggt ccgggggacc tttttagctt cttgccctga aattaaaaag caagaaaaac
     5221 ctccactgga ggttttcagc ctctcatctt gaaataagaa agtgagagaa ggtccggggg
     5281 atcttgaacc tcgagtttag aaataagaaa atgaggcaga ttcggtaact cgaagagttc
     5341 gatttcatcg tcttacccct gcaacgatga ctaggtttga aaaagcttgc tagatcgcat
     5401 ttcaaaccag gcagcgactg cgtcaagaaa ttagaagaca aactcgtttt ctagctgtta
     5461 ctgagttgag cctttttact acgagcatag aaataaggaa gtgaggtagc atcatgaaat
     5521 ctattggtac gcaaatatta cagacagaac gtttgatttt aagaagattt gtggagagtg
     5581 atgcagaagc catgtttcaa aattgggctt catccgctga gaatctgacc tatgttacct
     5641 gggctcccca tcctgatgtc gaaatcactc gaaactcgat tcgcaattgg gttgcttcct
     5701 atactaatct caactattac aaatgggcca tttgtctaaa agaaaaccca gagcaagtga
     5761 taggagatat cagcatcgtt aagatagacg aggctgattt aagctgtgaa atcggctatg
     5821 tgctaggcaa ggcttactgg ggacatggta tgatgacaga ggccttgaaa gctgtcttgg
     5881 acttttgttt tactcaagca ggttttcaaa aggtcagagc acgttatgcc agtctcaacc
     5941 cagcttcagg tcgtgtcatg gaaaaggctg gaatgtccta tctacaaacc attgttaatg
     6001 gtgtagagag aaaaggctat cttgcggatc ttatttatta tggtataagt agggaagaat
     6061 gttgaattct attttctgtt tctatcgaag tcaactattt attgtaaata taataattag
     6121 cattccaagt ttatttgcaa tttta
//
LOCUS       DAVMCG010000068         5372 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVMCG010000068 DAVMCG010000000
VERSION     DAVMCG010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.069"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            33..980
                     /locus_tag="VYP66_001956"
     CDS             33..980
                     /locus_tag="VYP66_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV1851448.1"
                     /translation="MTEEKFQKIIQSKDTETLAFILESTPYHLSIDILEDPSQTEISL
                     MTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLKSKAAIKKDFSKLLIPIGIFD
                     IESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNE
                     LDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLLSDEGSISAKEFIYIVENQEI
                     FVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRYNVEGPLVLA
                     RYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYGS"
     gene            970..1290
                     /locus_tag="VYP66_001957"
     CDS             970..1290
                     /locus_tag="VYP66_001957"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV1851449.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            1353..3128
                     /locus_tag="VYP66_001958"
     CDS             1353..3128
                     /locus_tag="VYP66_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV1851450.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            3129..4514
                     /locus_tag="VYP66_001959"
     CDS             3129..4514
                     /locus_tag="VYP66_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV1851451.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            4537..5148
                     /locus_tag="VYP66_001960"
     CDS             4537..5148
                     /locus_tag="VYP66_001960"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV1851452.1"
                     /translation="MVRLNVKPTRMELNNLKERLTTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKSFAVAKSLKNSQMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIYKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
BASE COUNT         1780 a          769 c         1102 g         1721 t
ORIGIN      
        1 atacgacgat ttcggtaaaa gaaaacgatt ttattacaga agaaaaattt caaaaaatta
       61 tacaatccaa agatacggag acattggcat ttatcttaga atcaactccc tatcatttat
      121 cgattgacat cttagaagat cctagtcaga cagagatttc gctaatgaca aaattagtca
      181 atgattatag atgggcctat gctgaaagtc cgtctgatat aattgtgact ttatttgctt
      241 tacgatatgt ttatcataat atcaaagttt tattaaaatc taaggcggca attaagaaag
      301 atttttctaa attattaatt ccaataggga tttttgatat agaaagttta aaacatttag
      361 tttcttcctt acattcagat acacttcctg attttatggt tcgtgaagta gaatcaattt
      421 ggaatgagta tgaaactttt aataatattc gtgtacttga tgtcggagct gatctagcat
      481 attttaaaca tctgaaactt ttatctaatg agttagatga ggtactgtct caggttattg
      541 tcgaaatgat tgacttttat aatattatta ctgtaaaacg tggtttatct caaaataaga
      601 gtcatgggga tattttacaa ttactttcag atgaaggaag tatttctgct aaagaattta
      661 tatacattgt agaaaatcaa gaaatatttg tgtggttcaa taaaataaat ccaagcttag
      721 attcaatctt ttcaacttat gaattgaaga tgcaggacgc aacaatttca tcttctgagt
      781 tagaattttt atgtgattta ctattgtata aaactttaga tcaaggaagg tacaatgtag
      841 aggggccgtt agttcttgct agatatttat tgggatgtga gtttgaagta aagaatctca
      901 gaatgatcat atcagctctt caaaatacaa ttccctttga atcaataaaa gaaaggatac
      961 gcccacatta tggaagctaa taagtataaa attggcataa ttggtagccg tgatattatt
     1021 ttaccattta gcatgattgg gtttgatata tttcctgcct accaagaaca agaagctata
     1081 aatacactaa gaaaattagc tcaatctgat tatggtgtca tttatatcac tgaagacatt
     1141 gcttcaatga tattagatac aattcgccat tatgattccc aagttgtgcc tgctattatt
     1201 ttattaccga ctcataaaca aggtttaaat ttaggattaa aacgtataga ggataatgta
     1261 gagaaagcag taggacacaa tattttataa taatgtacaa aattgtctgt aatattattc
     1321 tataattttt ggacttagta aggagaataa ctttgactca agggaagatt ataaaagtat
     1381 cgggacctct agttattgca tcaggtatgc aggaggctaa tattcaagat atttgccgtg
     1441 taggtaagct agggttaatc ggtgaaatta ttgaaatgag aagagatcag gcatctatcc
     1501 aagtctatga agaaacatct ggtcttggtc cgggagaacc tgttgttaca actggagaac
     1561 ctctctcggt tgaattaggg cctggattga tttctcaaat gtttgatggc atacaacgcc
     1621 cattagatcg atttaaattg gctactcata atgattttct agttcgtggg gtagaagttc
     1681 caagtttgga tagagatatt aagtggcatt ttgattccac tatatcaatt ggtcaaaaag
     1741 tgagtacggg tgatattctt ggaactgtca aggaaaccga agtagttaat cataaaatta
     1801 tggttcctta tggaatatct ggcgaagtcg tttctattgc ctctggcgat tttacaattg
     1861 atgaagttgt atatgaaata aaaaaattgg acggtagttt ctataaagga acacttatgc
     1921 aaaaatggcc tgtccgcaag gcgcgtcctg tttctaaacg tttaatccca gaagaaccat
     1981 taatcacagg tcaacgagtt attgatacat tctttccagt aaccaaaggg ggagcagcag
     2041 ctgttcctgg accgtttgga gcaggaaaga cagttgtaca acaccaagta gctaaatttg
     2101 ccaatgttga tattgttatt tatgtcggtt gtggagaacg tggaaatgaa atgacggatg
     2161 tactgaatga gtttcctgag ttgattgacc ctaataccgg acaatcaatt atgcaacgga
     2221 cagttctgat tgctaatact tcaaatatgc ctgttgctgc tcgtgaggct tcaatttata
     2281 caggaattac catggctgag tattttcgtg atatgggcta ctctgtcgcc attatggctg
     2341 attcaacttc acgttgggca gaagcgctac gtgaaatgtc aggacgtcta gaagaaatgc
     2401 ctggtgatga gggttatcct gcttatctgg gaagtcgtat cgctgaatat tatgaaagag
     2461 caggacgttc tcaggttcta gggcttccag aacgtgaagg aacgattact gctattggag
     2521 ctgtatcgcc acctggtgga gatatttcag aaccagttac tcaaaacact ttacggattg
     2581 tgaaagtttt ttgggggctt gatgctccgt tggcacagcg acgtcatttt cctgcaatta
     2641 actggcttac atcttattca ctatataaag acagtgtggg cacttatata gatggtaaag
     2701 agaagacaga ttggaatagt aaaataactc gtgcgatgaa ctacttacaa cgggaatcta
     2761 gtttagagga aattgttcgt cttgttggaa ttgattctct gtctgataat gaacgactaa
     2821 cgatggaaat tgctaaacaa attcgagaag attatttgca acagaacgct tttgattcgg
     2881 tagatacatt cacttcgttt gcaaaacaag aagcaatgct aagtaatatt ctcacttttg
     2941 ctgatcaggc aaatcatgct ttagagttgg gttcttactt tacagagatt atggaaggta
     3001 ccgtggcagt tcgagaccgt atggcgagaa gtaaatatgt ttcagaagat agattagatg
     3061 aaatcaaaat tatatcaaat gagattacac atcaaattca tttgatatta gaaacaggag
     3121 gtctataaat gagtgttata aaagaataca gaactgctag tgaagttgtt gggcctctta
     3181 tgattgttga acaagtaaat aatgtgtctt acaatgagtt agttgaaatt caacttcata
     3241 atggagaaat tcgtcgtgga caagttttag agatccacga agataaagca atggttcagc
     3301 tttttgaagg atctagtgga ataaatttag aaaagtctaa aattcgtttt gctggtcatg
     3361 cattagaatt ggctgtatct gaggatatgg ttggtcgtat ttttaatggg atgggaaaac
     3421 caattgatgg tggaccagat ttaattccag agaaatattt agatattgat ggtcaagcta
     3481 ttaatcctgt atctagagat tatccagatg aatttattca gacagggatc tcctctattg
     3541 atcatttgaa tactcttgta cgtggtcaaa aattaccagt attttcaggt tcgggcttac
     3601 ctcataatga attagctgct cagatagcaa gacaagcgac tgttttaaat tctgatgaaa
     3661 attttgcggt tgtatttgca gcaatgggta ttacttttga agaagctgag ttttttatgg
     3721 aagaactcag aaaaacagga gcgatcgatc gttcggtttt atttatgaac ttggcaaatg
     3781 atcctgcaat tgagcgtatt gcaactcccc gcattgcttt aactgcggca gagtatctag
     3841 cttttgaaaa agatatgcac gttctagtta tcatgacgga tatgactaac tattgtgaag
     3901 cgttacgtga agtctcggca gctcgccgtg aagttccagg gagacgaggc tatccgggat
     3961 atttatatac aaatttatca actctatacg aaagggctgg tcgcttagtt ggtaaaaaag
     4021 gttcggtgac acagattcct attttaacaa tgccagaaga tgacataaca catccaattc
     4081 ctgatttaac tggatacatt actgaagggc aaattatttt gtcgcatgag ttgtataatc
     4141 aaggttatcg tccaccaatc aatgttttac cttctctctc tcgattaaaa gataagggat
     4201 ctggagaagg taaaactcgt ggagatcatg ctccaactat gaatcaactg tttgcagcct
     4261 atgcccaagg gaaaaaggtt gaagagttag cagtagtatt aggagaatcg gctttatctg
     4321 atgtagataa attgtatgtg aggtttacaa agcgttttga agaagagtac ataaaccaag
     4381 gattttataa aaatcgaaat atagaagata cgttgaatct tgggtgggaa ttactatcaa
     4441 ttcttcctag aacagagtta aaacgtatca aagatgattt gcttgataaa tacttacctt
     4501 tggtagaagt ttaatccgga aatggagtga ttatctatgg tacgtttgaa tgtaaaacca
     4561 actcgtatgg aattgaataa cttaaaggaa cgtttgacaa cagctgaacg tggacataag
     4621 ttattaaagg ataaaagaga tgaattgatg aggcgattta tttctttgat tcgtgagaat
     4681 aatcaacttc ggaaagaagt ggaaagttat ctaattgata atctaaaatc ctttgcagtt
     4741 gctaaatcat taaagaattc tcaaatggtg gaggaattat tttcaattcc atcgaaagaa
     4801 attgaattat ttgttgagaa agaaaatatc atgagtgtaa cagttcctag aatgcatatg
     4861 aatattactt ctcaaaatga gaacagtgaa tacagctatt tatcttctaa tagtgaaatg
     4921 gatgatgtat ttgctacaat gaatagttta atttataaat tactaagact ggcagaagtt
     4981 gaaaaaacgt gtcagttaat ggctgatgaa atagaaaaaa cacgtagacg tgtaaatggt
     5041 ttagaatact cgattattcc aaacttgtcg gaaactattc attatataga attgaaacta
     5101 gaggaggcag aaagagccaa tttagttcgt attatgaaag tgaagtagat cctttattta
     5161 gattattaat tagatgaaca aatatcagct tggataaggc tttaagcctt tctaagcttt
     5221 ttttattgac agtatcagga tatctttttc aaaattttgg tttgttagat aatgaaaatg
     5281 tttctactaa tctagattta ggattagtaa atcgtaaatg taattatata gaaagtaagc
     5341 gcgtcataac aaggtatcta tcattcatgg ag
//
LOCUS       DAVMCG010000069         5207 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVMCG010000069 DAVMCG010000000
VERSION     DAVMCG010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.070"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            104..631
                     /locus_tag="VYP66_001961"
     CDS             104..631
                     /locus_tag="VYP66_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1851453.1"
                     /translation="MEDYCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNT
                     RKAQGRHLEQEGNIKHALIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQ
                     TLMESLSDDDYDFAFDEALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKY
                     ECYSPLNNLELDDFE"
     gene            complement(797..868)
                     /locus_tag="VYP66_001962"
     tRNA            complement(797..868)
                     /locus_tag="VYP66_001962"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(833..835),aa:Arg,seq:cct)
     gene            complement(910..1257)
                     /gene="rplS"
                     /locus_tag="VYP66_001963"
     CDS             complement(910..1257)
                     /gene="rplS"
                     /locus_tag="VYP66_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1851454.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1376..1705)
                     /gene="crcB"
                     /locus_tag="VYP66_001964"
     CDS             complement(1376..1705)
                     /gene="crcB"
                     /locus_tag="VYP66_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1851455.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1699..2073)
                     /gene="crcB"
                     /locus_tag="VYP66_001965"
     CDS             complement(1699..2073)
                     /gene="crcB"
                     /locus_tag="VYP66_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1851456.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(2070..2336)
                     /locus_tag="VYP66_001966"
     CDS             complement(2070..2336)
                     /locus_tag="VYP66_001966"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1851457.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2452..2895)
                     /locus_tag="VYP66_001967"
     CDS             complement(2452..2895)
                     /locus_tag="VYP66_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1851458.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2999..3934
                     /locus_tag="VYP66_001968"
     CDS             2999..3934
                     /locus_tag="VYP66_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1851459.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNITDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3988..4272
                     /locus_tag="VYP66_001969"
     CDS             3988..4272
                     /locus_tag="VYP66_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1851460.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4329..4547)
                     /locus_tag="VYP66_001970"
     CDS             complement(4329..4547)
                     /locus_tag="VYP66_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851461.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     IAHYGRVETAISFLPSSMEIEPTDESGT"
     gene            complement(4544..5118)
                     /locus_tag="VYP66_001971"
                     /pseudo
     CDS             complement(4544..5118)
                     /locus_tag="VYP66_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1665 a         1093 c          899 g         1550 t
ORIGIN      
        1 caatttagat attccgttcg aatttaaact aacaaaagaa gcacaaaatc ttattatcga
       61 acatagtgac tatatcaaag catactatga taaagacata actatggaag attattgtaa
      121 agaaaaaaac aatatctctt ttaaagcaac ttttggtgat ataaaatgga gtctcttaaa
      181 taaacaagct cataggaata ctgtatcagg agattttgga tgcttatcta acacacgaaa
      241 ggctcaggga agacatttgg aacaagaagg taatattaaa catgctttaa tatattacat
      301 agaatctttg ataattacta tttcaggatt agaaaacaat ttttcagcca ctgattatcc
      361 agtatattat cccgattcga tacctgacta ctcactaaaa catattcaaa cattaatgga
      421 atcattatct gatgacgatt atgattttgc ttttgatgaa gcattatttc gcttctcaat
      481 tttgaatgca aatcattttt tatctaagga agatattgac tatttaagag ttaatttacc
      541 tcgttccact gctgaagaaa taaacaatta cttaaagaaa tatgaatgtt atagtccttt
      601 aaataattta gaacttgacg attttgaata aattgactat acaaacattt atatactcga
      661 tatagtctca attttatctg atgattgccc aaatttttca ataataaaac gcataatatt
      721 atggagacaa tcccctatat tatgcgttct tttaatatca aagacttttt gacaaacttc
      781 ttcgatatct aattactgcc ccctgcagga atcgaacctg caactactcc ttaggaggga
      841 gttgttatat ccattgaact aagggagcta gataaaaact ctgctgaaaa gcagagtttt
      901 ttagtcgaat taacgacgga tttctttgat acgagctgcc ttaccttgaa gagcacgcaa
      961 gtagtacaat ttcgcacgac gtactttacc gtaacgaaca acttcgattt tttcaacacg
     1021 tggagtgtgg attgggaaga tacgctcaac acctacaccg ttagagattt tacgaactgt
     1081 gtagttttct gagattccag cacctttacg tgcgataaca acaccttcaa aaatctggat
     1141 acgttcacgg ttaccttcga caactttcgc atgtacacga acagtgtcac caggacggaa
     1201 tgatgggata tctgtacgaa gttgaccttc agtcaagctt tggattaatg gattcatttt
     1261 attctcctat ctttgtcaat cttgaggaat cttcctcagc ggataaactg tatttttgtg
     1321 cgtccattac acacaagata tagtttacca aatttctaaa aaaaagtaaa gaaatttata
     1381 gcaaaattcc taaaaaaatc gcaaccaaac cacctatgta agtcaaagtc aggtaagaat
     1441 aaaagacctt cttatcactt agcagtcttt gaagttcgtc attcaaggtc gaaaaagttg
     1501 ttaaaccgcc acaaaatcct gttgctagaa tagcatatac ttccttagac tctacatgat
     1561 tgtagaatac tccaattaaa aaacaaccta aaagattagc tatgagcgtt ccgagtggca
     1621 atttagaagc ttgattatag cgagaaaaga aataccgtac gagtgctccc aagccacagg
     1681 cgattgcaag atagacgatt accatttctt cctccccaaa tagtaagcta aaagcaggcc
     1741 tccaccgata ctcaaaagca aatacagtat caaactaaga taacgccctg tatcaagcag
     1801 cttcacagta tcaagcatta ggctggaaaa agttgttaaa cctccgcaaa aacccgtccc
     1861 cagtgctaaa atcaagccct tactagtccc cttatagacc agatagccct tgacaagata
     1921 aatcaagcag aaaattccca gatagttgac aaagagagtg ccccaaggga aatctggact
     1981 ggctggtaac caagtggaaa ctaggtagcg gacaagtccg cccaacatag cagctagaaa
     2041 aatccctagc ggataaaatt gttctttttt catttgatat tttgatcctg ataatcacgc
     2101 gaacgtttga gtatgtccga aaaagtcgcg acaatagtct cctgatagcg cttgtcctct
     2161 acacgacttc taaccttttc aaaaataact gcttctctct tagtatctaa aatcggtttc
     2221 cctgaagcct tcttataagc gacaactcct tcaactaagt gcattcgttc ttctaacagt
     2281 ttgacaattt ggtcgtcgat ttgatcgatt tcttgacgaa taatatctaa atccatacag
     2341 tctcctcctt tatttgaatt attgtatcaa aaagccatca attaggctag taaaatccca
     2401 actctcgata agaaaaatgc actgattgat tacatcagcg cacttttatg cttatcctac
     2461 tttagcagcc aattcttctg cgaattgttc caagcgttca atatcttctt cctcggcaga
     2521 aagatcaact ttaacacact ctgaaccttt ttctgctcct gttgacacaa agacacggtc
     2581 aaagtcatca acagccttac aaaattcatc gtagaaggta tctcctgagc cgaccactcc
     2641 gtagattttg ccattcaagt tgagatctgc taggtcttcg tagaagtcca tcatctcatc
     2701 tggcaattca ccatcaccat aagtataggt cgcaacgata gcgatgtctg cttccaagaa
     2761 gtctgaagcg tcaacagttg tacattcatc aacatcaaca tccaagccca agtcacgtaa
     2821 tttgtctgct acaatatctg caatttcttc ggtattaccg gtcatactgg caaatacaat
     2881 ttttgctaat gccatatcgt cctcctcaat ttatctttct ccattatatc acatcttttt
     2941 cattttaaaa ataaaaattc ttgtgctaca atgaaatgag aaagaattga ggttatttat
     3001 ggagatttgc caacaaattt tagaaaaaat taaagaatac gacaccatta tcattcatcg
     3061 tcatatgaaa ccagaccctg atgccttggg aagtcaggtg ggattgaaag ccttgctaga
     3121 acatcatttc ccagaaaaaa ccatcaaagc cgtcggtttt gatgaaccaa ctcttacttg
     3181 gatggctgag atggatcttg ttgaagatag agcctaccaa ggcgcacttg tcatcgtctg
     3241 tgatacagct aatactgctc gtatcgatga taagcgctat agtcaaggtg attttctcat
     3301 taagattgac caccatccaa atgatgatgt atacggtgac ctgtcttggg tcgatactag
     3361 ttcaagtagc gctagcgaga tgattaccct atttgcccaa acaacccaac tagccttggc
     3421 agatcgcgat gctgagttgc tctttgcagg aattgtcggt gatacaggtc gcttcctcta
     3481 cccttctacc actgcacgga ctcttcgcct ggctgcttat ttgagagaac ataactttga
     3541 ctttgcggct ctcactcgca aaatggacac tatgagctac aaaattgcta aactgcaagg
     3601 ctacatctac gaccatctgg aagtggatga aaatggtgct gctcgcgtta tcctgagtca
     3661 gaaaatcttg aaacaataca atataaccga tgctgaaact gcggccattg taggtgcacc
     3721 tggacgcatt gacagagtga gtctctgggg aatttttgtc gaacaggctg atggccacta
     3781 ccgagttcgc ttacgcagta aagtccatcc tatcaatgaa attgccaagg agcatgatgg
     3841 tggaggccac cctctagcaa gtggtgctaa ttcctatagc ctagaagaaa acgaaatcat
     3901 ctaccaaaag ttaaaaaact tgcttaaaaa ctgataaaat acttgccaaa cttttcagaa
     3961 tctgatagac tagtatagta acaatctatg gctcgcaaag agaccatggc agaaaggaaa
     4021 tattgcaaaa tgaaaaaaga tatccatcca gaatatcgcc cagttgtctt catggacaca
     4081 actactggtt accaattcct tagcggttca acaaaacgct ctaacgaaac agttgagttc
     4141 gaaggcgaaa cttacccatt gatccgtgtg gaaatttcat cagactcaca cccattctac
     4201 actggacgtc aaaagttcac tcaagcagat ggacgcgtgg atcgtttcaa caaaaaatac
     4261 ggtctcaaat aatgataaga gaacagtttt ggctgttctt ttttgtttct tgaaatcaac
     4321 tgctgttttc atgttccaga ctcatctgta ggttcgattt ccatgctact aggcaggaag
     4381 gaaatagctg tttcaacacg tccataatga gctatactat tgtcacgaac cacactttca
     4441 ttgatggtcc aagtggaatt cattttctta aaagcttctc ggactttttc caaatctttg
     4501 gaggcaatgg cctgctctaa ggtttcaaaa cgaggactta tactcatctg ctttcaaaaa
     4561 gcattctagt ccatctccga ttaccgatgg actttatcac ctccttctcc agtccttgta
     4621 tgacatcttg aagttgattc atgacatctt ccaaagttcg aaaggcttta ttcttaaatc
     4681 cacgtttacg aatctctttc cacacttgtt caatgggttc atctctggtg tgtatggagg
     4741 aataaaggta aaatcaatat tagtcggaat atttaaggta cttgatttat gccatatagc
     4801 attgtccata acgagtaaaa ggataagctt gtgaaagctc ttctaaaaag gcgttcatcc
     4861 acactccttt ttataaacct gaaataaggc atcaattgta acaaattctc ctgcctctgt
     4921 agccttcaaa tgacgggcaa gaaaggcttt ctcttcctca actgtcatat atgcatggtt
     4981 acgaccacca cgtgtttctt gaaggagaga gtcgagtccg aactcctcat atttttttac
     5041 gtttcgccaa atcgttgttt gattacagtc taaaagctct ataatctctt tataagattt
     5101 gcccatcaga cgaaatatag tagattgaaa ctagaatagt acacctctac ttctaaaaca
     5161 ttgttagaaa tcgatttgtc ctgttcttgt ttcattttac tatagaa
//
LOCUS       DAVMCG010000070         5057 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVMCG010000070 DAVMCG010000000
VERSION     DAVMCG010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.071"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(180..1595)
                     /locus_tag="VYP66_001972"
     CDS             complement(180..1595)
                     /locus_tag="VYP66_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1851462.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1608..3446)
                     /locus_tag="VYP66_001973"
     CDS             complement(1608..3446)
                     /locus_tag="VYP66_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1851463.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIVLVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     FSNLEVEVGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3464..4303)
                     /locus_tag="VYP66_001974"
     CDS             complement(3464..4303)
                     /locus_tag="VYP66_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEV1851464.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4604..4786)
                     /locus_tag="VYP66_001975"
     CDS             complement(4604..4786)
                     /locus_tag="VYP66_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1851465.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            4846..>5057
                     /locus_tag="VYP66_001976"
     CDS             4846..>5057
                     /locus_tag="VYP66_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1851466.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMIHKV"
BASE COUNT         1722 a          955 c          658 g         1722 t
ORIGIN      
        1 tatataacca atctatccta agttaactat ttataatcga ctctctgtaa caaaattaaa
       61 ttaattaatc cccctataaa ataaagaggt ttagaatttg atgtcttcca aatctcttta
      121 tttcatattt aatgagatgt tgccttaacc gtgataatat ctaatcatca ataaacaaac
      181 tatttgaata aggattctcc atttgattca atcactcctt tataccaagt aaaggacatt
      241 ttcttatatc gattgaatgt gccatttcca tcatcatttc gatcaacata aatgagaccg
      301 taccttttag aaagttgtgc agtggacata gaaacacagt caatacatcc ccaagacgta
      361 tagcccataa tttcaacacc atcctgtaga gcttcagcaa cttgcaataa atgttctttc
      421 atatactgaa ttctataatc atcttggact gttaagttat taaattcatc ttttattagt
      481 tgatctttag cacctaatcc gttttccact ataaataatg gaatttgata acggtcataa
      541 tatctattta aaattatacg tagtccaatt ggatcaattt gccatcccca ctcagaagac
      601 tctaaataag gatttactaa gccaccaata atattccctt ctcctgaatt atactgtgtt
      661 ggaagagcag attgagtcac actcatgtaa tagctaaagg ataaaaaatc tacggtataa
      721 ttttttaata actctgcatc ttcagctgca aactctatgt taatgtcatg ttccttaaaa
      781 tatctttttg cataattcgg ataataacct ctaacatgca catctgaaaa tagataattt
      841 agattctcat actcatgagt cgcccataca tcttttggat ttggagtcat tggataagct
      901 ggcatagcta ataccataca tcctacctta aactctgaat taatctcacg agcaattttt
      961 gtaaccaaac ttgaggcgac taattcatga tgtatagctt gatataattc ttgtttcgaa
     1021 agattctcct taggtatatc tattcctcca ctagtaaatg gtaattccaa aacagagttt
     1081 acttcgttaa atgtaagcca atatttaact ttatctttat acctttctaa aactgttcga
     1141 gcaaattttt cataaaaatg aatcattctc ctatcaaccc atccatgata ttttcttgct
     1201 aaatataatg gagtctcata gtgtgaaaga gttacaagtg gctctatccc gtgagcatgt
     1261 agttcatcaa acaattcatc ataatatttc aaaccagctt cgttaggttc ttcttcatct
     1321 ccttttggaa aaattctact ccatgcaata gaagtacgaa aaacattaaa gcccatttca
     1381 gaaaacaagg atatatcttc cttatattta tgataaaaat caatacctaa caattttaag
     1441 ttatcttctg taggattttc tgttgcttct cctaatccac ctttgggtaa cacatcctga
     1501 actgataagc ccttaccatc ttcattatat gctccctcta cttgattagc tgcaacagct
     1561 ccaccccaaa gaaaatcatc tggaaaaatg gtcataactt tcctccatta taatattacc
     1621 agtaattcct tagaatgctc gattgtctga ttattaggta atactaatac atctagaaaa
     1681 tcattggtat tcgttacaat tactggtgta actgtttcgt agcctttagt cttgattaaa
     1741 ttcaagtcca tttcaaaaat caactgattt ttgaaaactc tgtctccttc ttctacatga
     1801 ctaataaaac cttgaccttt tagctcaaca gtatctaatc caatatgaat tagtaactca
     1861 acaccctcat cactcttcaa tccaattgcg tgcttagtcg gaaaaatatt tgtaattttc
     1921 ccatcaaatg gtgcataaac cttaccttca cttgggataa ttgctactcc gtctccaatt
     1981 agtttatctg aaaatgtttt atcctggaca tcgcttaacg gaatgatttc tcctgatata
     2041 ggagaaaata tcattttttt atttgaaact ccaacttcaa cttctaaatt gctaaaactc
     2101 tcttcttcat cgattccaaa tatataagct aatacaaagg taataacaac cgaaatgacc
     2161 gccacaatta aagcatttac aatatttgat ggcacatcag aataaataaa ttgaggcaac
     2221 gctatcaaag atgggacagc aaatagatat gctttaacac tagtaagacc tgcaaataat
     2281 cccgctaatc caccaccaat catagctgca taaagcggtt ttttatattt taaagtcaca
     2341 ccatataatg caggttcggt aatccctgca agtaaggctg agaaacctgc tgcaaaagca
     2401 atttgttttg tattattatt tttactcttt aatgcaacag ccatcgaagc agccccttga
     2461 gctaagtttg accctaacat tgctggaaga attaatacgt ctggagtagc aatagatgcc
     2521 gccaaaaaaa taggtgcaaa agcccaatgc attccagtca taacaataaa tggcataata
     2581 gcaccaagaa tagctaatgt aagccatcca gctacaccat acatttgccc aactagattt
     2641 gataatcctt caccaacaat tactccaata ggtccgacta caactaagac aatacagctt
     2701 gatactaata atactagcgt aggttgcaaa aaactcttag taatagctgg tgttaattta
     2761 gcaattattt tttcaatata tttcatcaac caaaccataa taagaattgg aacgactgac
     2821 gaaccataac tagctggtgt cacaggtaca ccaaataaac taagaggatt ccctgattgc
     2881 accatttgaa caaaatttgg atggagaagt acacctgcta cagacatagc taatgtagat
     2941 gttactttta atttttgtga tgcagaataa gctaataaca gcggtaagaa ataatatgga
     3001 gcatccccaa aaaatgtcaa aaaagcaata gtctgagaat ctgattgcaa tataccaagc
     3061 attggtaaaa taattaccaa gactttcagc atacctcccc ctaacattgc tggaatgatt
     3121 ggagtcatgg aaccagcgat atactcaatg attctttcta aaatattccc tttgtgccct
     3181 tgaacaactg aatcggattc aaaattgcca agtttaacga attctttata ataattagct
     3241 acatcattac caagtataat ttgatattgt ccattctttt tcataatacc tattacacct
     3301 ggtatcttct tcacatcatc atcattgact aaattttcat cttttaattc taatcttaaa
     3361 cgtgttacac aatgggtaac tctattgaca tttttttcac ctccaattac atcgaggatt
     3421 ttttgtacct tatctttata actcatggta ttctcctatt ctattaatct aaattttttg
     3481 ttaagcgacg aatatgagcc atcaaataaa ctaattcact agaagtcagc aaataattgt
     3541 actcagtttg tataaacatt gccacctgtt caccacattc atattctcta ggatatttat
     3601 ttttcattaa tgctaacaag tcttcatcat catcgtcaca ataagttgta ttttcaacca
     3661 agcgatgggc aaataatttt atatgagtta tgaatctata ataatcaata gaatcttggt
     3721 taaactcagt acaatagaaa tcttgaatga ttttctcaat tcccataatt atttcagtga
     3781 ttttatacga ctcttgaaaa ttattttcta aattagcatt aacaaaatgt agcgctatga
     3841 atgcagcttc gtcaattgga agttcaatac ctaactcttt ttttattatt tgtaaagccc
     3901 ttttcccaag ttcaaattct tctttataat atttcgatat ttcccagcgt aggggattcg
     3961 aaataataac tccttcttta taacgttcta tactcgaaga aatatgatcc gttagattta
     4021 tatagataat ctcatcaaaa ttattaccta atgttatttt acctagatta attatttttt
     4081 cggtgatgta caccaactcc aaaggaacgt taataaacat ctctgtaaaa cgggtcatat
     4141 tatctctatt tttgagaaaa aaacttttct caatatcaat tggatttact ttatctccaa
     4201 tttttcttcc aaaagctatt ccccttccaa aaagaagaat atcgatatct tttttacttt
     4261 gcgcaattac ggcattgtgg tttagtattc gttttatgat cataaaattt cccttttaaa
     4321 ataaaaggaa cctacttaaa aaacatcaag aaacttcttc tgatgtgatt aaataggttc
     4381 ctgctcactt gtattagtga taacatcctt ttatttcaat ttttaatggt gacatgaagc
     4441 ttaaataatt aataactctg taaccgtttt tattttatga tatttcaatc tatttgtcaa
     4501 gtacttataa aaattttttt attttgtgtg attcgaatgt gataatggca acagtctcac
     4561 taaagaaatg aaaatcatac atagaaattt ttaaaaattt tctctatcgt aaacctgcca
     4621 ctagttcaga aactatacta gctgattcca aacgtaatat ggtcatctca tctaccttcc
     4681 ctaataatgg cattgcacca taccaaacaa tagtcttatt caccaaaaga ataggcgtta
     4741 ctatttttga ttgagtaaaa gacactttaa ttttctggct cttcaactgt gaactacacc
     4801 ccaaaagtta gacagaaaaa atctaacttt tggggtgttt ttattatgaa attaacttat
     4861 gatgataaag ttcagatcta tgaacttaga aaacaaggat atagcttaga gaagctttca
     4921 aataaatttg ggataaataa ttctaatctt agatatatga ttaaattgat tgatcgttac
     4981 ggaatagagt tcgtcaaaaa aggaaaaaat cgttactatt ctcctgattt aaaacaagaa
     5041 atgattcata aagtctg
//
LOCUS       DAVMCG010000071         4898 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVMCG010000071 DAVMCG010000000
VERSION     DAVMCG010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4898
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.072"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(212..940)
                     /locus_tag="VYP66_001977"
                     /pseudo
     CDS             complement(212..940)
                     /locus_tag="VYP66_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(1186..1497)
                     /locus_tag="VYP66_001978"
     CDS             complement(1186..1497)
                     /locus_tag="VYP66_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851467.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1512..2798)
                     /locus_tag="VYP66_001979"
     CDS             complement(1512..2798)
                     /locus_tag="VYP66_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1851468.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            3422..3604
                     /locus_tag="VYP66_001980"
     CDS             3422..3604
                     /locus_tag="VYP66_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1851469.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            3614..3976
                     /locus_tag="VYP66_001981"
     CDS             3614..3976
                     /locus_tag="VYP66_001981"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1851470.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEHLRAVTGID
                     LLSILTDIANKKTGVKSK"
     gene            3973..>4898
                     /locus_tag="VYP66_001982"
     CDS             3973..>4898
                     /locus_tag="VYP66_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1851471.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRN"
BASE COUNT         1673 a          892 c          824 g         1509 t
ORIGIN      
        1 agttttctgc ttattaattt ttttcaaaat atctaagaca tcgcttcttt gtttaatttg
       61 ataggctttg atacctaagc tccgacttta tcacttaaaa aataaaaaag acagctaatc
      121 ccttgcgcat caagggattt cgccattctt taatctcgtt taagtgttgt atatggagct
      181 ttgcataatt ttttaaaact aaacaactac attaagcacg aactgtgacg ctggttccat
      241 cttccttata aagattgata agcccctctt taagagctcg aaccatgtct ccagcttgaa
      301 caggttgtgg gactttaata gtcaatagtt ccattggatt tggagcgcgg tcgattttat
      361 tgcctttggc atcatgcaaa tcttcaatat aggtttcaaa atgacggaaa cctggaccat
      421 aaaactcaac ttggtcccct tcgttaatga catttcgttg acgaatagtt gctgtttgtg
      481 ccgcatcatc ataagaaacc acttcagcga caaacttgta ctcaggaatt ttacgacgag
      541 caccaaacaa ctgctcattt tcagatggtg taccatagta aaatcctgta gccagttcac
      601 gttgggcaac cttccacatc tcgtccacca agtcttgttt gatagcttca aacttttcag
      661 gactttcaag ataggcatcc acagccgcct tgtagcagtt ggttactgtt aatacatagt
      721 gaatagactc catacgtcct tcgattttta gactgtccac accattttca atcatatctg
      781 gaatgtggtc aatcatagac atgtcaacgg ctgacattga aaattcttct ggaatctcac
      841 cctgcaaact cttacgttct ttcccaaatg gcatatcgta aaggtcgtac ttccaacggc
      901 atgactgaga acatccacca cggttggcat cacgcatact ctagacggat tgttttgaca
      961 attctaatct tttagacttt gcataataac tgttaaacag ttgaaaatta acccagtttt
     1021 aacaagtagt caaaatacca gataaaggaa aaaagtcttt aaaatcttaa aaacgcatag
     1081 tatcaggtat tgaacaatct tgatattatg cgttttattg tgggaagatt tacttcattt
     1141 tctcttggaa ttgagttttc tcctacttca aaactagatg atttgctatt taaaatagcg
     1201 ttccttatga ttttggcaac ctggattaaa gcgagaaaaa caaaaggggc aacttaaact
     1261 ttctttatat tgcttatatg ttagtagttt tagacaaaca ccacataaaa taggcttatc
     1321 ctgtatcaaa gataagggat acggctcaaa agggtgattt tctaatgaat catgacaccg
     1381 ataacaagca taatactttt tacaatcata gcattgtaaa gcaataatat ccagcttgct
     1441 atggtaatga atgcatcttg tttgcttatc cactaagaaa ccctgtgcct ctatcatttc
     1501 cttttccttt cttaagctcg aactgtgacg ctggttccat cttccttata aaaattgatg
     1561 agtccttctt ttaatgcacg aaccatgtct cctgattgaa cgggttgtgg gactttaata
     1621 gtcaatagtt ccattggatt tggagcgcgg tcgattttat tgcctttggc atcatgcaaa
     1681 tcttcaatat aggtttcaaa atgacggaaa cctggaccat aaaactcaac ttggtcccct
     1741 tcgttaatga cgtttcgttg acgaatagtt gctgtttgta ccgcatcatc ataagaaacc
     1801 acttcagcga caaacttgta ctcaggaatt ttacggcgag caccaaacaa ctgctcattt
     1861 tcagatggta taccgtagta gaaacctgtt gccaattcac gttgggcaac cttccacatc
     1921 tcgtccacca agtcttgttt gatagcttca aacttttcag gactttcaag ataggcatcc
     1981 acagccgcct tgtagcagtt ggttactgtt gatacgtagt gaatagactt catacgtcct
     2041 tcgattttta gactgtccac accattttca atcatatctg gaatgtggtc aatcatagac
     2101 atgtcaacgg ctgacattga aaattcttct ggaatctcac cctgcaaact cttacgttct
     2161 ttcccaaatg gcatatcgta aaggtcgtat ttccaacggc atgactgaga acatccacca
     2221 cggttggcat cacgcatact catgtggttt gaaagagtac aacgtccaga gtatgaaata
     2281 cacatagctc catggacaaa ggcttcaatt tcaacatctg tacgtttgcg gatttcagct
     2341 aattcttcca ttgaaacctc acgcgctaaa acgacacgag tcaagcctag ctctttccag
     2401 aactcaaggg tttcatagtt agtggcactg gcttgggtag aaaggtggat ttcaaggcct
     2461 ggtgcttcag tagctgcaat cataatcaag gctgggtcag atacgataac tgctgcaatc
     2521 ccgatatcac gcagtttacg gaaccactca ccagcaccag cttcatttcc ttcgtgcata
     2581 accatattag ccgctacata gaccttggca ccatacttgg ccgcaaactg cacgccttct
     2641 tccatctgtt cgaaagtaaa gtttccggca cggctacgaa gaccataggc ctgaccaccg
     2701 ataaagacag catctgctcc atactgaaca gctaccttta gcttctctaa agtccctgca
     2761 ggtgataaaa cctcaggacg ttttaatgtt tttgtcataa tttctcctat ttgcaatata
     2821 aaagtttgac atttttcctt ctcattttat agtaaataaa ggataaaatc aagcctagac
     2881 ggattgtttt gacaattcta atcttttaga ctttgcataa taactgttaa acagtcgaaa
     2941 attatcccag ttttaacaag tagtcaaaaa gtctagaaaa gtaaaaacca gtatccaaag
     3001 atactgactc gtaaaaatac ataaattagt ccttagatga ctactcccac tctgttgctc
     3061 ctataatgga aaaggattga tacagtctag aatatcgctt ttttatttat tattctgata
     3121 taaaactgtt agaattgatt ttttgtttta tacccaaata tgaatagaga cgtagctaat
     3181 aagttgaata acatatttgg aaaaatgaga aatagcaata ttactagaac ttttagaaac
     3241 aatcaatatt taaaaagaaa aaagctcaaa gaatttatta aaccatgtta taatagatat
     3301 agctataatt ttatttataa caagaggata gaaatgaccg aattagaaag aaaaaatcga
     3361 aaaattagct aagaaatatt ctgataactt aaacatcaaa gttcaagaga gagttcgtga
     3421 aatggcaaat gataataaga gccattattt gatatacaga gttttaggta tttcatttga
     3481 agaaggagaa aatatcgatt tgtatcaaaa taaaggtcgt tttttataca aatatgctgg
     3541 ttcattttta gaagaagctg cagtactatc ctttaacgaa aaatttggta cagaaaatac
     3601 ttaaaaagtt aacattccta attctgaaag tacaaaacct aagacttttg aaattgattg
     3661 tttagtcgga gaaaaacacg catacgaaat aaaatggtgg gatgcaacta cagatggaga
     3721 ccatataact aaagaacaca ctagaataaa agttattcat aacaaaggat atataccaat
     3781 tcggttaatg ttctactatc caaatagaac tcaagctata aaaattcagc aaactttaga
     3841 aacattgtat aacggtattg gagggaaata ttatggagat tctgcctggg aacatttaag
     3901 agcagtgacc ggtattgatt tacttagtat tctaacagat attgcaaata aaaaaacagg
     3961 ggtaaaatca aaatgacagt attaaaagga gataacttag aaatattaaa aactattgaa
     4021 tcctcaagta ttgatttaat ctatatggac cctcctttct ttacacagaa aacccaaaaa
     4081 ttatctaata acaaaaatat tatgtattca ttcgaagata cgtggacttc gattgaggat
     4141 tacaaagaat ttttgtctgt aagattagaa gaatgcaaaa gagtgctaaa aaatagtggc
     4201 agtattttcg ttcattgtga taaaattgca aatcatcata ttagattaat tttagataat
     4261 atctttggag cagatatgtt tcaaagcgaa attatatgga actataagcg gtggtctaat
     4321 tcaaaaaagg gattattgaa caatcatcaa aacatttact tttattcaaa gtcaaaagat
     4381 tttaaattta atacaatttt tacagagtat tcttctacta caaatatcga ccaaatacta
     4441 gtggaacgaa aacgagatgg aaactctaaa actatatata aagttgataa taatggtaac
     4501 tatattctag caaaagagaa aaatggagtt cccctttcag atgtttggaa tataccattt
     4561 cttaatccaa aagctaaaga aagagtaggt tatcctacac aaaaacctat tctgttatta
     4621 gaacaaatta taaagattgc tactgataaa aatgatatag ttttagaccc gttctgtgga
     4681 agtggaacta ctttagtagc ctccaagatt ttgaatagaa attatatggg gattgattta
     4741 tctgaggaag ctatcaatat aactcagcaa cgtctggaaa atgttataaa aacaagttca
     4801 aatttattga ataaaggaat cgaagcatat agaaccaaaa ctgaggaaga ggaaaacatt
     4861 cttaaattat tacaggcaaa aattgttcaa agaaataa
//
LOCUS       DAVMCG010000072         4693 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVMCG010000072 DAVMCG010000000
VERSION     DAVMCG010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.073"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            189..938
                     /locus_tag="VYP66_001983"
     CDS             189..938
                     /locus_tag="VYP66_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1851472.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCSDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIIFWIKK"
     gene            951..2122
                     /locus_tag="VYP66_001984"
                     /pseudo
     CDS             951..2122
                     /locus_tag="VYP66_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
     gene            2517..3380
                     /locus_tag="VYP66_001985"
     CDS             2517..3380
                     /locus_tag="VYP66_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1851473.1"
                     /translation="MIERMELGEFYKELRLARKLKQSDVACEGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYVPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            3846..>4693
                     /locus_tag="VYP66_001986"
     CDS             3846..>4693
                     /locus_tag="VYP66_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEV1851474.1"
                     /translation="MDRLQTMLNKIQVDTYHKNGWLFVKYSNNKLTQGWKLHVSSQLK
                     DACNIFYIVAQELEKERCNYKVLDCLDELKKLNSPREVSPTANKFITIYPSSRKQAKR
                     IILNLKEKLEKYKAPRILSDFQCGEYSPIHYRYGAFKAIKNYNFSENKIVYMMKNSRG
                     ELVEDLRLSYPYLPEGVKDLFTDMEKNKLFKPSPEIPENHPLNHYNIECILKKSNRGN
                     VYRAIEKSSNQKVIIKHARPYVYSWNDGFSAIDELKSEAANLKVFQDKSYTTDLIEEF
                     YVNEDY"
BASE COUNT         1688 a          626 c          855 g         1524 t
ORIGIN      
        1 attgtaaatg ggctgataca aaatattgag gagaatttag aggatgatat tgaaaggata
       61 ttgaaatatt tatatatatg tttatttaac gaaatattca ttattaagaa taaggtgaat
      121 ttttttgatg atgtggaatt taatcagaca cttagtgagt ttttagataa attgtagagg
      181 gaatggttat gagtaacaat actaagtata tctttttatc tccacattta gatgacgcaa
      241 ttttttcctg tagtgattat atttcaaaat taacttcaga aggagaaatt gtacttgtta
      301 ttactatatt ttctggttac cctttgagcc aacagctaca gccctctgct aagcaatttc
      361 ataagttgtg taaccttggg aaatatccga ttgaagaaag gaagaaagaa gacaggttag
      421 cttgtgaacg tctacaatgt gattttagac acttatcgta ctatgaatgt ctctatagga
      481 aagatagaaa tggcaatttt ctataccgtc atatctatag tgaattaaaa aatgaggaca
      541 cattaaagaa tgatatcata aaagagctgt taatgcattt agacgataaa tgtgtcgtat
      601 attgtccgct ttcacttggt gaccatgttg atcatgtttt tgtgaatagt attggaaggg
      661 cgcttgaatt tatgcgttat aaagtaatat attatgagga tttcccatat gtaagtgata
      721 gtagtatggt tagttatatg ggaaaaacta aagaattaaa aatgtatcaa gaggaacttg
      781 atgaaaaaca ttatattgat agaatatcat caatattgtg ctataaatct cagattttga
      841 taatctggaa atcagttgaa aaacttttaa acaatattaa agagttgtat ttaaggaatg
      901 gggcagctta ttctattata ttttggatta agaaataagg aagtagtttt atgaatatag
      961 cagtaattgg tttggggcat gttgggctgg cctacgcgtt actatttgca tctaaatata
     1021 aagttgttgc atatgatata gattctgtaa aaataaataa tttaaaaaag ggcattcttc
     1081 catctaaaaa tgaagagctt atgaagtttt tttgcgagaa taacttaaat attacttttt
     1141 ttgatacatt ttctgaaatt aaaaataata ttgattatta tattattgcg cttccgacag
     1201 attatgatga gaaaattggt agttttaata catatgaaat cgaacaaacg gtatcgaaga
     1261 ttctgagggt aaaacctaat ggaaagatta ttttaaagtc aacagttccg atcggctttt
     1321 caaacaaatt aaaaaggctg tttgatacaa aaaatatcat ttttgtccct gaatttttga
     1381 gagaaggttg ttctatatat gataatttat atccaagtcg catagttgtt ggagatgaga
     1441 cagttgaagg aagaaaaatt gcagagttgt tcctttcgat tagtactcat agtactgcca
     1501 atattaaaaa tgttatgtta gtttctccta ctgaagcaga agcaattaag cttttttcta
     1561 acacattctt agctctccgt gttgcttttt taatgaacta gattcttttg ctgagaggag
     1621 aagtttaaat gctgaagttg taataaaagg tgtttgttta gatccaagaa ttggaaattt
     1681 ttataataat ccttcttttg gatttggagg atattgtctt cccaaagata ctaaacaatt
     1741 aaaaaaagaa tttatagaaa taaatgcccc agtgatagaa gcgattgata tttcaaacac
     1801 aaatagaaaa cagttcatag ttaaacaaat attggaacga aagccaaaga tagtaggaat
     1861 atataaattg gggatgaaat ataattcaga taattacaaa gagtcagcta ttttaagtat
     1921 aattaatgaa ctattgattg tcggtataaa aattttagta tatgaaccaa atttaaacgt
     1981 tagtatagat aacgtaattt ttgaaaagaa ttttgaacta tttacaaaac aaagtgatct
     2041 aattgttgca aatagatggg ataggggcct tgaagcttat aaagataaag tttacacaag
     2101 ggggatctgg ataagagatt aactattgat attaaaaagg caataattta taaaatttgt
     2161 acaaaaaaat gttaaatttt cacattttca tagtatactg tttaatagaa agtaggttct
     2221 ttgtaaccgc tccattataa aatcctttca ctcttccggt atactattag gaaaaacata
     2281 actggaggat attttgagct cacacctcat cgttccagtg gctgttcccc aagctcgtgt
     2341 actgcccaaa aaagttagac attctattta gaacgaggat tgagttctgt attgtacaag
     2401 gctcggtcct tttagagtca gcttaaggct ggcttttttg ccctcttaaa tatcagaata
     2461 ttttgacaaa tgattgtaaa taatgatata atatgcaaaa gctaggaggt ggtcagatga
     2521 ttgagagaat ggaattggga gaattttaca aggaattgcg cttggcgaga aaacttaagc
     2581 agtcagatgt ggcctgtgag ggtctaacag cttctcagtt gtccaagttt gaactaggac
     2641 agtctatgtt atctgcagat aagctcatat tagccatcca agggatcaat atgaattttg
     2701 atgagtttgg gcacaagctc aacaactatc aagaatctcc acatatgcga atcggtcgaa
     2761 aggttgtgga tcgctttgcc catcaggata tagctgcttt agagcagcta ttggaggaag
     2821 tcgatcaaga acagatggcg cagacctatc gtcgtttgaa tgccattgtg attaaaaatg
     2881 cactccattc cttagataaa agctacccgc taacagagga ggatagcgag tttttgacta
     2941 cctacctcta cgctattgag tcttggacct ggtttgaact ctatcttttt tgcaatacta
     3001 tgcccttctt gagcaatcaa gatctgatct ttttatcaac ctccttactc gaaaaatcca
     3061 aggaatttaa agagttagta cacaatcgat ggtatatgaa aagtggttat cttaatatca
     3121 tctcagaact tatggagcgc aagctatttt cttatgttcc aatctttgaa gctgagctgg
     3181 agcgcatgct ccgtccatac gatgtttttg aaaaagtatt gtggcagttt ttaaagaaaa
     3241 tgcagatttt tcttcaaacc aaaggaagca atcaaaaaga gattgaacac tttatccaat
     3301 ctctgcaagt attagaaaat ccacaattga cagccctttt tgaattgcgt ttgcagcaat
     3361 acaaagagct tatcgattag ttagaaatgg gaaaaagata ataatatcag caacgatcgt
     3421 caataatgtt aaaacttgtt tcttcatatt acttccctcc tcattagtaa taactttatt
     3481 ataccaggga aataatcaaa tctaccaaaa tcgcaaatct gaaatttcta taagaaaaaa
     3541 aatcaaatat gcgattttct aaaataagcc aatttccgtg ttatactgtc cttgtaaaac
     3601 atttgaagca aatcctaggt cgcagaagtg gtttacaaaa aaataatcaa aggagaaaag
     3661 aaatgcataa tctaatggaa cttgaattgt tacctgaaga gccagtaatt actgtatcac
     3721 gggaagtttg taagtggact tgctcattta ctgctcttta agaataactg gttaaaatta
     3781 aggatagttg attactaatt aactatcctt aatttcattt cagagataat gtatttatta
     3841 tatttatgga tagattacaa acaatgctga ataaaataca agttgatact taccataaaa
     3901 atggatggtt atttgtgaag tatagtaaca ataaacttac acagggatgg aaacttcatg
     3961 taagcagtca actaaaagac gcttgtaata ttttttatat tgttgcacaa gagctggaaa
     4021 aggaaagatg taactacaaa gttctagatt gtttggatga gttaaaaaaa ttaaattctc
     4081 ctagggaagt ttctcctact gcaaataagt ttatcactat atatccgtct agtaggaagc
     4141 aggccaaacg aataatatta aatctaaaag aaaagttaga aaaatataaa gctccaagga
     4201 ttttatcaga ttttcaatgt ggtgagtatt ctccaataca ttatagatat ggtgcgttta
     4261 aagcaattaa aaattacaat ttttctgaaa ataaaattgt ctacatgatg aaaaatagta
     4321 gaggagaatt agtagaagat ctgagattaa gttatccata tttgccagaa ggggttaagg
     4381 atttatttac tgatatggaa aaaaataaat tatttaaacc ctccccggaa atcccagaga
     4441 atcacccttt aaatcactat aatatcgagt gtattctaaa aaaatccaat agaggaaatg
     4501 tttacagagc tatagaaaaa agtagtaatc agaaagtgat aataaaacac gcacggccat
     4561 atgtttatag ttggaatgat ggtttctctg caattgatga attaaagagt gaagcagcaa
     4621 atttaaaagt atttcaggat aagtcctata caacagattt aattgaagag ttttatgtca
     4681 atgaagatta ctt
//
LOCUS       DAVMCG010000073         4663 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVMCG010000073 DAVMCG010000000
VERSION     DAVMCG010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.074"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..1341
                     /locus_tag="VYP66_001987"
     rRNA            <1..1341
                     /locus_tag="VYP66_001987"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1393..1465
                     /locus_tag="VYP66_001988"
     tRNA            1393..1465
                     /locus_tag="VYP66_001988"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1426..1428,aa:Ala,seq:tgc)
     gene            1590..4491
                     /locus_tag="VYP66_001989"
     rRNA            1590..4491
                     /locus_tag="VYP66_001989"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4568..>4663
                     /gene="rrf"
                     /locus_tag="VYP66_001990"
     rRNA            4568..>4663
                     /gene="rrf"
                     /locus_tag="VYP66_001990"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1294 a          962 c         1380 g         1027 t
ORIGIN      
        1 aaaaggtgca cttgcatcac taccagatgg acctgcgttg tattagctag ttggtggggt
       61 aacggctcac caaggcgacg atacatagcc gacctgagag ggtgatcggc cacactggga
      121 ctgagacacg gcccagactc ctacgggagg cagcagtagg gaatcttcgg caatggacgg
      181 aagtctgacc gagcaacgcc gcgtgagtga agaaggtttt cggatcgtaa agctctgttg
      241 taagagaaga acgagtgtga gagtggaaag ttcacactgt gacggtatct taccagaaag
      301 ggacggctaa ctacgtgcca gcagccgcgg taatacgtag gtcccgagcg ttgtccggat
      361 ttattgggcg taaagcgagc gcaggcggtt agataagtct gaagttaaag gctgtggctt
      421 aaccatagta ggctttggaa actgtttaac ttgagtgcaa gaggggagag tggaattcca
      481 tgtgtagcgg tgaaatgcgt agatatatgg aggaacaccg gtggcgaaag cggctctctg
      541 gcttgtaact gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt
      601 agtccacgct gtaaacgatg agtgctaggt gttagaccct ttccggggtt tagtgccgta
      661 gctaacgcat taagcactcc gcctggggag tacgaccgca aggttgaaac tcaaaggaat
      721 tgacgggggc ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc
      781 ttaccaggtc ttgacatccc tctgaccgct ctagagatag agttttcctt cgggacagag
      841 gtgacaggtg gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc
      901 aacgagcgca acccctattg ttagttgcca tcatttagtt gggcactcta gcgagactgc
      961 cggtaataaa ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg
     1021 gctacacacg tgctacaatg gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat
     1081 ctcttaaagc cagtctcagt tcggattgta ggctgcaact cgcctacatg aagtcggaat
     1141 cgctagtaat cgcggatcag cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg
     1201 cccgtcacac cacgagagtt tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag
     1261 ccgcctaagg tgggatagat gattggggtg aagtcgtaac aaggtagccg tatcggaagg
     1321 tgcggctgga tcacctcctt tctaaggata aggaactgcg cattggtctt gtttagtctt
     1381 gagaggtctt gtggggcctt agctcagctg ggagagcgcc tgctttgcac gcaggaggtc
     1441 agcggttcga tcccgctagg ctccattggt gagagatcac caagtaatgc acattgaaaa
     1501 ttgaatatct atatcaaata gtaacaagaa aataaaccga aaacgctgta gtattaataa
     1561 gagtttatga ctgaaaggtc agaaaataag gttaagttaa taagggcgca cggtggatgc
     1621 cttggcacta ggagccgacg aaggacgtga caaacgacga tatgccttgg gtagctgtaa
     1681 gtaagcgatg atccagggat ttccgaatgg gggaacccaa caggtaatac ctgttaccca
     1741 catctgttaa ggatgtgagg aggaagacgc agtgaactga aacatctaag tagctgcagg
     1801 aagagaaagc aaaagcgatt gccttagtag cggcgagcga aacggcagaa gggcaaaccg
     1861 aagagtttac tcttcggggt tgtaggactg caatgtggac tcaaagatta tagaagaatg
     1921 atttgggaag atcagccaaa gagagtaata gcctcgtatt taaaatagtc tttgtaccta
     1981 gcagtatcct gagtacggcg ggacacgtga aatcccgtcg gaatctggga ggaccatctc
     2041 ccaaccctaa atactcccta gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa
     2101 agcaccccgg gaggggagtg aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc
     2161 ccgttaatgg gtgagagcgt gccttttgta gaatgaaccg gcgagttacg ttatgatgcg
     2221 aggttaagtt gaagagacgg agccgtaggg aaaccgagtc tgaatagggc gccttagtat
     2281 catgacgtag acccgaaacc atgtgaccta cccatgagca ggttgaaggt gcggtaagac
     2341 gcactggagg accgaaccag ggcacgttga aaagtgcttg gatgacttgt gggtagcgga
     2401 gaaattccaa acgaacttgg agatagctgg ttctctccga aatagcttta gggctagcgt
     2461 cgacattaga gattcttgga ggtagagcac tgtttgggtg aggggtccat cccggattac
     2521 caatctcaga taaactccga atgccaatga attatggtcg gcagtcagac tgcgagtgct
     2581 aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtccca aaataattgt
     2641 taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag aagcagctat
     2701 tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg
     2761 ggctaaaaca atttaccgaa gctgtggata cctttatagg tatggtagga gagcgttcta
     2821 tgtgtgatga aggtataccg tgaggagtgc tggaacgcat agaagtgaga atgccggtat
     2881 gagtagcgaa agacaggtga gaatcctgtc caccgtaaga ctaaggtttc caggggaagg
     2941 ctcgtccgcc ctgggttagt cgggacctaa ggagagaccg aaaggtgtat ccgatggaca
     3001 acaggttgat attcctgtac tagagtatgt agtgatggag ggacgcagta ggctaactaa
     3061 agcagacgat tggaagagtc tgtctaagca gtgaggtgtg aattgagtca aatgcttaat
     3121 tctataacat tgagctgtga tggggagcga agtttagtag cgaagttagt gacgtcacac
     3181 tgccaagaaa agcttctagc gtttaaacat actctacccg taccgcaaac cgacacaggt
     3241 agtcgaggcg agtagcctca ggtgagcgag agaactctcg ttaaggaact cggcaaaatg
     3301 accccgtaac ttcgggagaa ggggtgctga ctttaagtca gccgcagtga ataggcccaa
     3361 gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta tagggggtga
     3421 cgcctgcccg gtgctggaag gttaagagga gtgcttagcg taagcgaagg tatgaattga
     3481 agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat tccttgtcgg
     3541 gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac gagagactcg
     3601 gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa agaccccatg
     3661 gagctttact gcagtttgat attgagtgtc tgtaccacat gtacaggata ggtaggagtc
     3721 taagagatcg ggacgccagt ttcgaaggag acgctgttgg gatactaccc ttgtgttatg
     3781 gccactctaa cccagatagg tgatccctat cggagacagt gtctgacggg cagtttgact
     3841 ggggcggtcg cctcctaaaa ggtaacggag gcgcccaaag gttccctcag aatggttgga
     3901 aatcattcgc agagtgtaaa ggtataaggg agcttgactg cgagagctac aactcgagca
     3961 gggacgaaag tcgggcttag tgatccggtg gttccgtatg gaagggccat cgctcaacgg
     4021 ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat cgacggggag
     4081 gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc caagggttgg
     4141 gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag acagttcggt
     4201 ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg agaggaccag
     4261 agtggactta ccgctggtgt accagttgtc ttgccaaagg catcgctggg tagctatgta
     4321 gggaagggat aaacgctgaa agcatctaag tgtgaaaccc acctcaagat gagatttccc
     4381 atgattatat atcagtaaga gccctgagag atgatcaggt agataggtta gaagtggaag
     4441 tgtggcgaca catgtagcgg actaatacta atagctcgag gacttatcca aagtaactga
     4501 gaatatgaaa gcgaacggtt ttcttaaatt gaatagatat tcaattttga gtaggtatta
     4561 ctcagagtta agtgacgata gcctaggaga tacacctgta cccatgccga acacagaagt
     4621 taagccctag aacgccggaa gtagttgggg gttgccccct gtg
//
LOCUS       DAVMCG010000074         4643 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVMCG010000074 DAVMCG010000000
VERSION     DAVMCG010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.075"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            83..880
                     /locus_tag="VYP66_001991"
     CDS             83..880
                     /locus_tag="VYP66_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1851475.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSLLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFVLVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VYP66_001992"
     CDS             1028..1150
                     /locus_tag="VYP66_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEV1851476.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATKSRAVPIYQTTSFVFDDT"
     gene            1172..2287
                     /locus_tag="VYP66_001993"
     CDS             1172..2287
                     /locus_tag="VYP66_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1851477.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWMASGKFPQFVDEGSSCHNLSYTRDVGAVAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKINYPKLADSPYYALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATITHGQLS
                     EKDLEAAGVTPNQIHLSIGLENVEDLIEDLRLALEKI"
     gene            2383..3657
                     /locus_tag="VYP66_001994"
     CDS             2383..3657
                     /locus_tag="VYP66_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1851478.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3669..>4643
                     /locus_tag="VYP66_001995"
     CDS             3669..>4643
                     /locus_tag="VYP66_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEV1851479.1"
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYI
                     EHLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGEDFE
                     KRRLDFEKGYFKNLLPYSIVNQTVESLASLNAIFITSNYDYEIENHIKRLKNAVVTIN
                     DLNEFTKNKNGKLQFGDVLHIHGTPDCDVKYFVSSSADYSKTYLKNRENFENLVTWFK
                     ETKPTVLFVGAGLEEDEILSLLCKDSKNYALMKSENTGNQRVDEHYRGVVEGFFSSEN
                     HTQIIWYGDEFEKLPLFVKKLVADINEKLGTHDFYNQWNNLLNPSINQE"
BASE COUNT         1484 a          781 c          981 g         1397 t
ORIGIN      
        1 acttttatga aatatagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagttta ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggggttgta gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaaca ttgccattct
      601 ttcatttgtt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataagataa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 gactccagct actaagtctc gtgcagtgcc gatttatcaa acaacatctt ttgtttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaagataaat tatccaaaac ttgcagatag
     1981 tccttattat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aggaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagacttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cattgaaggg ggagtgagga
     3661 aataagttat ggaagatgat cttaattatg aaaatttgat ggatgatgta accgaggcta
     3721 taaaaaagtt taacttagta atttttattg gcgcaggagt ttcaattgct caaggttatc
     3781 ctaattggaa caattatatt gaacatctta ttaagtattg gcaaggacaa gttttatcgg
     3841 taagtggtga aaaaaggctt ggaagagaac atcacgtagt ttttgattta attagcaaat
     3901 ctagtattag taataaacgt aaagtggatc ttgtaaacta tgaattaaaa aaagtttttg
     3961 gtgaagattt tgaaaagcga cgactagatt ttgaaaaagg atattttaaa aatctattac
     4021 catattcaat agttaatcaa acagtagaat ctttagcaag tttgaatgca atatttatta
     4081 cttctaacta cgactatgaa attgaaaatc atattaaacg tttaaagaat gctgtagtta
     4141 ctattaatga tctcaatgaa ttcactaaga acaagaatgg gaaactacaa tttggtgatg
     4201 ttctacatat ccatggaaca ccagattgtg atgtaaagta ttttgtaagt tcatccgcag
     4261 attattcaaa aacctattta aaaaataggg aaaattttga aaatttagta acatggttta
     4321 aagagacaaa acctactgtt ttatttgttg gagcaggtct tgaagaagat gaaattttat
     4381 ctttactttg taaagatagt aagaactatg ccttgatgaa gtcagagaac acaggtaatc
     4441 agagagttga tgaacattat agaggtgttg ttgaaggatt ttttagctca gaaaatcata
     4501 ctcagattat ttggtacgga gatgaatttg agaaactacc tctttttgta aaaaaattag
     4561 ttgctgatat taatgaaaaa ttgggcacac atgattttta taatcagtgg aacaatcttt
     4621 tgaatccttc tataaatcaa gaa
//
LOCUS       DAVMCG010000075         4127 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVMCG010000075 DAVMCG010000000
VERSION     DAVMCG010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4127
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.076"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            720..1712
                     /locus_tag="VYP66_001996"
     CDS             720..1712
                     /locus_tag="VYP66_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1851480.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQILSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VYP66_001997"
     CDS             1714..2532
                     /locus_tag="VYP66_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1851481.1"
                     /translation="MIKLWIRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKQVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VYP66_001998"
     CDS             2534..3319
                     /locus_tag="VYP66_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1851482.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3624
                     /locus_tag="VYP66_001999"
     CDS             3358..3624
                     /locus_tag="VYP66_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1851483.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGAN"
     gene            3573..3818
                     /locus_tag="VYP66_002000"
     CDS             3573..3818
                     /locus_tag="VYP66_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1851484.1"
                     /translation="MSRRKKAYQGRKIGSQLIATLESEARKKVAYLQVKTVAEGSNKD
                     YDRTNDFYRGLGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1152 a          694 c          892 g         1389 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gaatgataaa attaatcaat tgatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cgatgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aatttcacaa tccataggca atcgcttgca ttctgttttt tattggacta
      601 taataggttg gtataaagcc ttctgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccaggata atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccagact cgctctttca taagcgtatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaatca agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctggtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctatca gtcagctgac attatcaagc
     1621 aaatcctgtc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggat acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacagg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ttggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccga aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagt tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactagatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgattgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 cttatctgca ggtcaaaaca gtggcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcttcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttacttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagcttagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatccctgt taagtacgaa acttttg
//
LOCUS       DAVMCG010000076         4021 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVMCG010000076 DAVMCG010000000
VERSION     DAVMCG010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.077"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..588
                     /locus_tag="VYP66_002001"
     CDS             <1..588
                     /locus_tag="VYP66_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1851485.1"
                     /translation="LYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRN
                     KNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYK
                     PSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLTG
                     LKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
     gene            798..3917
                     /gene="phtE"
                     /locus_tag="VYP66_002002"
     CDS             798..3917
                     /gene="phtE"
                     /locus_tag="VYP66_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1851486.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGISHEKHEEDGYGFDANRII
                     AEDESGFIMSHGNHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1504 a          663 c          788 g         1066 t
ORIGIN      
        1 ctttatgagg cacctaaggg gtatagtctt gaggatcttt tggcgactgt caagtactat
       61 gtcgaacatc caaacgaacg tccgcattca gataatggtt ttggtaacgc tagcgaccat
      121 gttcaaagaa acaaaaatgg tcaagctgat accaatcaaa cggaaaaacc aaacgaggag
      181 aaacctcaga cagaaaaacc tgaggaagat aaggaacatg atgaagtaag tgagccaact
      241 caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc agataatctt
      301 tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac tacagatgag
      361 gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga ggcggaggcc
      421 ttgctagaaa aagtaacaga ttctagtatt agacaaaatg ctgtggagac attgactggt
      481 ctaaaaagta gtcttcttct cggaacgaaa gataataaca ctatttcagc agaagtagat
      541 agtctcttgg ctttgttaaa agaaagtcaa ccgactccta tacagtagta aaatgaatgg
      601 agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa aaacgtaaca
      661 gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta aatggttaaa
      721 taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac ttcatcattt
      781 attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga tcagctgtta
      841 tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag gaaaataagg
      901 acaataatcg tgtctcttat gtagatggca gccagtcaag tcagaaaagt gaaaacttga
      961 caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta atcaaaatta
     1021 cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat gggaaagttc
     1081 cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat caacttaaag
     1141 acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat ggaaaatatt
     1201 atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat gaaatcaatc
     1261 gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt gctgtagcaa
     1321 ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct gatattatcg
     1381 aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac attcccaaaa
     1441 gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga aaaaatatgc
     1501 aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa tctgtagcaa
     1561 aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt ttgaaggaac
     1621 tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc tttgaccctg
     1681 ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac cattaccact
     1741 ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg gtgcctatca
     1801 gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg tctagtctag
     1861 gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct tcagcatctg
     1921 atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct tatattgtaa
     1981 gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa ccgactcttc
     2041 caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga atttcacatg
     2101 agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct gaagatgaat
     2161 caggatttat catgagtcac ggtaatcata atcattactt cttcaagaag gacttgacag
     2221 aagagcaaat taaagctgcg caaaaacatt tagaggaagt taaaactagt cataatggat
     2281 tagattcttt gtcatctcat gaacaggatt atccaggtaa tgccaaagaa atgaaagatt
     2341 tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt gtcaaacgtg
     2401 aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga gatcaccatc
     2461 atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac agtaactatg
     2521 aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt tatactggag
     2581 aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat caaaacttta
     2641 ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg gagaaaaaat
     2701 taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg gagaaagtat
     2761 ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta gatcaacctt
     2821 atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca gaagtaagtt
     2881 atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt caaacgattt
     2941 tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt gcagtgccta
     3001 aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct tatttagaaa
     3061 ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa ggaacaacca
     3121 gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg gacaatcaat
     3181 cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat aaaccaagta
     3241 ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat gaaaaggtag
     3301 aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact gggaatagta
     3361 ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa aaagtagcaa
     3421 aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg gacggaacaa
     3481 ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat tttacaggag
     3541 aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta tctactggaa
     3601 cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag gcaccaaacg
     3661 aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca gaagggaatg
     3721 tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta gatcctgtac
     3781 aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt gttatattca
     3841 atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa aagaatttat
     3901 ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat gaagttctct
     3961 caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt aatatataaa
     4021 a
//
LOCUS       DAVMCG010000077         3994 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVMCG010000077 DAVMCG010000000
VERSION     DAVMCG010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.078"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            106..1515
                     /locus_tag="VYP66_002003"
     CDS             106..1515
                     /locus_tag="VYP66_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1851487.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDFEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            1533..2828
                     /locus_tag="VYP66_002004"
     CDS             1533..2828
                     /locus_tag="VYP66_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1851488.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            2833..3141
                     /locus_tag="VYP66_002005"
     CDS             2833..3141
                     /locus_tag="VYP66_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1851489.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            3138..3446
                     /locus_tag="VYP66_002006"
     CDS             3138..3446
                     /locus_tag="VYP66_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1851490.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1351 a          667 c          752 g         1224 t
ORIGIN      
        1 aatgaggcaa acacaagata tgtatcaaca atttttaaaa atgtctagac aaattttgaa
       61 attatgctat actttatgta tagaataata gaaaggaggt tgagcatgaa aaaaaagtta
      121 gtatttccta atctgttttg gtggggagca gcttctagcg gacctcagac agaaggtcaa
      181 tatggaaaag tacatgaaaa tgtgatggac tactggttca aaacgcatcc agaagatttt
      241 ttcgataatg tcggacctct tgtagccagt aacttttttc atacttacac cgaagatttc
      301 cacttgatga aggaaattgg agttaattct ttccgcactt ccatccaatg gagtcgactc
      361 atcaagaatt tagagacagg tgagcctgat ccaaaaggta ttgctttcta caatgccatc
      421 attgaagaag ctaaaaagaa ccagatggat cttgtgatga atttacatca ttttgattta
      481 ccagtggaac ttcttcaaaa atacggtggt tgggaaagca aacatgtagt ggagttattc
      541 gtgaagtttg ccaagactgc tttcacatgc tttggagata aggttcatta ctggacaact
      601 ttcaatgagc caatggtcat tccagaagca ggatacttat atgctttcca ttatccaaat
      661 ctaaaaggaa agggaaaaga ggccgtacaa gtcatctata atctaaacct tgctagtgca
      721 aaagtgattc aactatatcg ctcattagaa cttgatggaa agattgggat tattttaaac
      781 ttgacacctg cttatccaag aagtaattct ccagaagact tcgaagcaag tcgatttaca
      841 gatgacttct ttaacaaagt cttcttgaat ccagctgtta aaggaacttt cccagaaaga
      901 ttggtaaaac agctagagag agatggcgtg ttatggagtc ataccgaaaa agagcttcaa
      961 ctgatgaaat caaatacggt tgattttctt ggagtaaact actaccatcc aaaacgtgtt
     1021 caagcacaag caaatcctga ggaatatcag acgccctgga tgccagacca atacttcaaa
     1081 gagtatgaat ggctggagcg tcgcatgaat ccatatcgtg gttgggaaat ttttccgaaa
     1141 gccatttatg atattgctat gattgtgaag gaagaatatg gtaatatccc atggtttatc
     1201 agtgaaaacg gaatgggtgt tgaaaacgaa gcacggttta tcgatgaaaa tggagttatc
     1261 gatgacgtgt atcgtattga attttatgaa gaacatttaa gatggctaca taaagccatt
     1321 gaagagggaa gtcactgttt tggataccac gcttggaccg catttgattg ctggtcttgg
     1381 aataatgcat ataagaatcg ttacggattt atctccgttg atttagaaac gcaaaagaga
     1441 accatcaaga gctcaggaag atggtatcgc aaagtaagtg acaataacgg ttttgaagta
     1501 gaaattgagg agtaaagaga ggagatattc atatgaaaaa ctcaaaattt atagaccaat
     1561 ttgccacctt tgctggtaaa ctagggaacc aaattcattt aaaaacccta agagatgcat
     1621 tcgtaacagt aatgccatta tatattttgg caggtttaat cgttcttttg aacaacacgg
     1681 tatttaagtg gattttccaa ggggatacat taacaagatt ccaatattgg ggaataacaa
     1741 ttgcaaacgg tactttaagt atttcaggta tgattattgc tgtaatggtt ggttatttct
     1801 tagctaaaaa cagagatttc gaaaacccgt tagcagcatc aatgctatca ttagtttctt
     1861 taattgtgat gatgccaaat acagtttctg tagttcctga cggagcaaaa gatgctgtaa
     1921 acatttcagg tgttctttca ttcaacaaca caggtacagg cgcaatgttc gccggggtta
     1981 tcgtagcgat tattgcaaca gaattattca ttgaattatc aaatgttaaa gctttacaaa
     2041 tgaaccttgg tgaaaatatt ccaccagctg ttagtagatc atttagcgta ttacttccag
     2101 tcatgaccgt catctcctta tttggggttg tttcagcatt attgttcaat ataactggaa
     2161 tgaacttaat ctcaatcatt acaatcttta ttcaagaacc aattcgtcat attggtacaa
     2221 gcttaatcgg ggtcattatt atttactctt taggaaatat gttatggcta tttggtattc
     2281 accaagcagt tatttacagt gccatcctag aaccattact attaattaac attactgaaa
     2341 acatcactgc agcaaataat ggacaagcca ttccacacat catcaaccta tcacaaatac
     2401 aaacattcgc tttaatgggt ggtagtggat ctacattatg tttattaata gcaacattct
     2461 tagtgagtcg caatgctgtc tctaaaaacg tggctaaatt atcttttgga cctggtatct
     2521 tcaatatcaa tgaaccagta ttattcggtt acccaatcgt ttataacatt tcattagcta
     2581 ttccatttat cacagttcca gtccttggta ttttaatcag ctacttagca acagttacag
     2641 gattcatgag tcctgcattt atacaagttc cttggactac accagtattc ttaaatgcat
     2701 ggttagcaac agcaggggac gtgagagcag ttctagttca attcatcatc tttgcacttg
     2761 gagttcttct atacattcca tttatcaaag ttaatgacaa agttgttgaa caagaaatgg
     2821 aaggttaaga ttatgaaaca aattttatta gtatgtaatg cgggaatgtc gacaagtatg
     2881 cttgttaaaa aaatgcaaca aagtgcgact gaacgtggga ttgaaatctc tatccaagca
     2941 aaatcaatga cagaagctaa aaagaatatc catgaagcag atgtcattct aattgggcca
     3001 caaattcgtt atgagttact tgctgtgaaa gaaattgcag gaaatatccc tgtagatacc
     3061 attgatatgc gggattacgg aatgatgaat ggagcaaaag ttctggaaca agcacttgca
     3121 tggataggag aaataagatg acagaagaaa tggaatatat ctgttttcag ctcattgcca
     3181 atagtggagc agccaaatca tcctttattg aagccatcca actagctaag gcaggaaatt
     3241 taaaagaagc gaaaattaaa gttgaagaag cggaagactc cttagtagaa gcgcacaaga
     3301 ttcactctaa tctcatacaa aaagaagcta ctggagaaaa aataggattc tccttgctat
     3361 ttatgcatgc agaagaccaa atggcttcaa cagagattat tcagttgcta tctaaagaat
     3421 tcatcgatct ctatcaaaat aaataggaac actgtcattc ccatctgtct ttattaatga
     3481 cgactacatt gtaggaacct ccaaaagttg gacaaaatga ttgaaaggat tggatcctgc
     3541 attacacaag atccaatcct tttcttttac tctagttttt ataatatgtt gaatctagaa
     3601 tagtccactg tagtttctaa aaaattgctg gaaatggatg ttaagctcca atttatttgt
     3661 ttatatctta tttcagttta ctatactagc ttattattct agtgaaaaat tgaatgagcc
     3721 actatttatt taatatgtat gatgagggaa tgactcaaaa acttcttgtc gatataagaa
     3781 tatctgagat agtattttaa aacgaaagga ctataaaagc tcatttcctt cgcacttatt
     3841 ttatagaaat ctatcattat actctttaga aatcaaaaag caacacacct tgtcatcgtt
     3901 ttctcgtttg ctctttgatt ttaattgggc cttagtaaat actactctta aattaaacta
     3961 tagtgaattg aaataagatg tgaacaactc tatc
//
LOCUS       DAVMCG010000078         3761 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVMCG010000078 DAVMCG010000000
VERSION     DAVMCG010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.079"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            158..385
                     /locus_tag="VYP66_002007"
     CDS             158..385
                     /locus_tag="VYP66_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851491.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKN"
     gene            673..3570
                     /gene="nanA"
                     /locus_tag="VYP66_002008"
     CDS             673..3570
                     /gene="nanA"
                     /locus_tag="VYP66_002008"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1851492.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKETLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGIEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1296 a          620 c          845 g         1000 t
ORIGIN      
        1 gttttaaaaa taaggtataa taaatttact aacacttata aaaagtgata gaatctatct
       61 ttatgtatat ttaaagatag attgctgtaa aaatagtagt agctatgcga aataacagat
      121 agagagaagg gattgaagct tagaaaaggg gaataatatg atatttaagg cattcaagac
      181 aaaaaagcag agaaaaagac aagttgaact acttttgaca gtttttttcg acagttttct
      241 gattgattta tttcttcact tatttgggat tgtccccttt aagctggata agattctgat
      301 tgtgagcttg attatatttc ccattatttc tacaagtatt tatgcttatg aaaagctatt
      361 tgaaaaagtg ttcgataaga attgagcagg aagtatggta taaatagcat aagctgatgt
      421 ccatcatttg cttataaaga gatattttag tttaattgca gcggtgtcct ggtagataaa
      481 ctagattggc aggagtctga ttggagaaag gagaggggaa aattggcacc aatttgagat
      541 agtttgttta gttcattttt gtcatttaaa tgaactgtag taaaagaaag ttaataaaag
      601 acaaactaag tgcattttct ggagtaaatg tcttatttca gaaatcggga tatagatata
      661 gagaggatca gtatgaatcg gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa
      721 ctatcggtag gagcggtttc tatgattgta ggagcagtgg tatttggaac gtctcctgtt
      781 ttagctcaag aaggggcaag tgagcaacct ctggcaaatg aaactcaact ttcgggggag
      841 agctcaaccc taactgatac agaaaagagc cagccttctt cagagactga actttctggc
      901 aataagcaag aacaagaaag gaaagataag caagaagaaa aaattccaag agattactat
      961 gcacgagatt tggaaaatgt cgaaacagtg atagaaaaag aagatgttga aaccaatgct
     1021 tcaaatggtc agagagttga tttatcaagt gaactagata aactaaagaa acttgaaaac
     1081 gcaacagttc acatggagtt taagccagat gctaaggctc cagcattcta taatctcttt
     1141 tctgtgtcaa gtgctactaa aaaagatgag tacttcacta tggcagttta caataatact
     1201 gctactctag aggggcgtgg ttcggatggg aaacagtttt acaataatta caacgacgca
     1261 cccttaaaag ttaaaccagg tcagtggaat tctgtgactt tcacagttga aaaaccgaca
     1321 gcagaattgc caaatggtcg agttcgcctg tatgttaatg gtgttttatc tcgaacaagt
     1381 ctgaaatctg gcaatttcat taaagatatg ccagatgtaa cgcatgtgca aatcggagca
     1441 accaagcgtg ccaacaatac ggtttggggg tcaaatctac agattaggaa tctcactgtg
     1501 tataatcgtg ctttaacacc agaagaggta caaaaacgta gtcaactttt taaacgctca
     1561 gatttagaaa aaaaactacc tgaaggagcg gctttaacag agaaaacgga catattcgaa
     1621 agcgggcgta acggtaaacc aaataaagat ggaatcaaga gttatcgtat tccagcactt
     1681 ctcaagacag ataaagaaac tttgatcgca ggtgcagatg aacgccgtct ccattcgagt
     1741 gactggggtg atatcggtat ggtcatcaga cgtagtgaag ataatggtaa aacttggggt
     1801 gaccgagtaa ccattaccaa cttacgtgac aatccaaaag cttctgaccc atcgatcggt
     1861 tcaccagtga atatcgatat ggtgttggtt caagatcctg aaaccaaacg aatcttttct
     1921 atctatgaca tgttcccaga agggaaggga atctttggaa tgtcttcaca aaaagaagaa
     1981 gcctacaaag aaatcgatgg aaaaacctat caaatcctct atcgtgaggg agaaaaggaa
     2041 gcttatacca ttcgagaaaa tggtactgtc tatacaccag atggtaaggc gacagactat
     2101 cgcgttgttg tagatcctgt taaaccagcc tatagcgaca agggtgatct atacaagggt
     2161 gaccaattac taggaaatat ctacttcaca acaaacaaaa cttctccatt tagaattgcc
     2221 aaggatagct atctatggat gtcctacagt gatgacgacg ggaagacatg gtcagcgcct
     2281 caagatatta ctccgatggt caaagccgat tggatgaaat tcttgggtgt aggtcctgga
     2341 acaggaattg tacttcggaa tgggcctcac aagggacgga ttttgatacc ggtttatacg
     2401 actaataatg tatctcactt aaatggctcg caatcttctc gtgtcatcta ttcagatgat
     2461 catggaaaaa cttggcatgc tggagaagcg gtcaacgata accgtcaggt agacggtcaa
     2521 aagatccact cttctacgat gaacaataaa cgtgcgcaaa atacagaatc aacggtggta
     2581 caactaaaca atggagatgt taaactcttt atgcgtggtt tgactggaga tcttcaggtt
     2641 gctacaagta aagacggagg agtgacttgg gagaaggata tcaaacgtta tccacaggtt
     2701 aaagatgtct atgttcaaat gtctgctatc catacgatgc acgaaggaaa agaatacatt
     2761 atcctcagca atgcaggtgg accgaaacgt gaaaatggga tggtccactt ggcacgtgtc
     2821 gaagaaaatg gtgagttgac ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc
     2881 tataattcgc tccaagaatt aggaaatggg gagtatggta tcttgtatga acatactgaa
     2941 aaaggacaaa atgcctatac cctatcattt agaaaattta attgggactt tttgagcaaa
     3001 aatctgattt ctcctaccga agcgaaagtg aagcgaacta gagagatggg caaaggagag
     3061 atgggcaaag gagttattgg cttggagttc gactcagaag tattggtcaa caaggctcca
     3121 acacttcaat tggcaaatgg taaaacagcg actttcctaa cccagtatga tagcaagacc
     3181 ttgttgtttg cagtagataa ggaagatatc ggacaagaaa ttattggtat agctaaagga
     3241 agcatcgaaa gtatgcataa tcttcctgta aatctagcag gtgccagagt tcctggcgga
     3301 gtaaatggta gcaaagcagc ggtgcatgaa gttccagaat ttacaggggg agttaatggt
     3361 atagagccag ctgttcatga aatcgcagag tataagggat ctgattcgct tgtaactctt
     3421 actacaaaag aagattatac ttacaaagct cctcttgctc agcaggcact tcctgaaaca
     3481 ggaaacaagg agagtgacct cctagcttca ctaggactaa cagctttctt ccttggtctg
     3541 tttacgctag ggaaaaagag agaacaataa gagaagaatt ctaaacattt gattttgtaa
     3601 aaatagaagg agatagcagg ttttcaagcc tgctatcttt ttttgatgac attcaggctg
     3661 atacgaaatc ataagaggtc tgaaactact ttcagagtag tctgttctat aaaatatagt
     3721 agattgaaat aagatgtgaa caactctatc aggaaagtca a
//
LOCUS       DAVMCG010000079         3417 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVMCG010000079 DAVMCG010000000
VERSION     DAVMCG010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.080"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            36..>3417
                     /locus_tag="VYP66_002009"
     CDS             36..>3417
                     /locus_tag="VYP66_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1851493.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALPEAVVTDKG
                     EPAVQPELPEAVVTDKGEPEVQPELPEAVVTDKGEPEVQPALPEAVVSDKGEPEQVAP
                     LPEYTRPQAGAVVEPAIQPELPEAVVTDKGETEVQPESPDTVVSDKGEPKQVAPLPEY
                     TGPQASAIVEPEQVAPLPEYTGVQAGSIVEPEKVEAPKEYTGKIEQPSAEDTKPENEA
                     SSTNGESERPKDKIKEEKQVDKKLELRNVSNVELYTVENNKYRHITAVDGALDSSLKY
                     FMKVKSENFKDIMLPVTKIESTTKNNKEVYKIVAHAENLIQHENNVISNDYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSDPNGTFHLGATMDAREVELPDDQESYVKNEFYGKLIGE
                     NNGKYYAIYNLKKPLFKTLNTATIQNLSIKEANVSSKEDAATISKEAKYNTLIDNVHS
                     DGIIAGERGIGGLVSKVDNSRISNSSFTGRITNTYDTTVGYEIGGLVGKLSGSLASIE
                     KSIASIDIASNAKSGDQIVGGIAGVVEKSATIKYSYVEGNVNNVRHFGKVGGVAGNLW
                     DRDSQDVSKSGKLSYVLSDVNVTNGNAISGDNFDNMKEDHAYSSKGNKVVNVVQVDDE
                     LVTKDSDVQRGTVLDADKVKEKKAELVSKHSTKVEDFDFTSRYTTIYNEVTGYQKSRE
                     QVYKNIEKLLPFYNRETIVKYGNLVDESSELFTKELLSV"
BASE COUNT         1293 a          522 c          696 g          906 t
ORIGIN      
        1 tgtaacatat ataaatttta tttcaaggag gaataatgga aaagtatttt ggtgaaaaac
       61 aagagcgttt ttcatttaga aaattatcag taggacttgt atctgcaacg atttcaagtt
      121 tattttttat gtctgtatta gctagttcat ctgtggatgc tcaagaaact gcgggagttc
      181 actataaata tgtggcagat tcagagctat catcagaaga aaagaagcag cttgtctatg
      241 atattccgac atacgtggag aatgatgatg aaacttatta tcttgtttat aagttaaatt
      301 ctcaaaatca actggcggaa ttaccaaata ctggaagcaa gaatgagagg caagccctag
      361 ttgctggtgc tagcttagct gctctgggaa ttttaatttt tgctgtttcc aagaaaaagg
      421 ttaagaataa aacggtatta catttagtat tggttgcggg aataggaaat ggtgtcttag
      481 tttcagtcca tgctttagaa aatcatcttt tgctaaatta caatacggac tatgaattga
      541 cctctggaga aaaattacct cttcctaaag agatttcagg ttacacttat attggatata
      601 tcaaagaggg aaaaacgact tctgattttg aagtaagtaa tcaagaaaaa tcagcagcca
      661 ctcctacaaa acaacaaaag gtggattata atgttacacc aaattttgta gaccatccat
      721 caacagtaca agctattcag gaacaaacac ctgtttcttc aactaagccg acagaagttc
      781 aagtagttga aaaacctttc tctactgaat taatcaatcc aagaaaagaa gagaaacaat
      841 cttcagattc tcaagaacaa ttagccgaac ataagaatct agaaacgaag aaagaggaga
      901 agatttctcc aaaagaaaag actggggtaa atacattaaa tccacaggat gaagttttat
      961 caggtcaatt gaacaaacct gaactcttat atcgtgagga aactatagag acaaaaatag
     1021 attttcaaga agaaattcaa gaaaatcctg atttagctga aggaactgta agagtaaaac
     1081 aagaaggtaa attaggtaag aaagttgaaa tcgtcagaat attctctgta aacaaggaag
     1141 aagtttcgcg agaaattgtt tcgacttcaa cgactgcgcc tattccaaga atagtcgaaa
     1201 aaggtactaa aaaaactcaa gttataaagg aacaacctga gactggtgta gaacataagg
     1261 acgtacagtc tggagctatt gttgaacccg caattcagcc tgagttgcca gaagctgtag
     1321 taagtgataa aggcgtacca gaagttcaac cagcgttacc ggaagcagtc gtaaccgaca
     1381 aaggtgagcc cgctgtccaa cctgaattac ccgaagctgt tgtaactgac aaaggcgagc
     1441 ctgaagttca acctgaatta cccgaagctg ttgtaactga caaaggcgag cctgaagttc
     1501 aaccagcgtt acccgaagcg gttgtaagtg ataaaggtga accagagcag gtagccccat
     1561 tgccagaata tacaagacca caagcaggtg cagtagttga acctgcaatc caaccagagt
     1621 taccagaagc tgttgtaact gacaaaggtg agactgaggt tcaaccagag tcgccagata
     1681 ctgtggtaag tgataaaggt gaacctaaac aggtagcacc gcttccagaa tatacaggac
     1741 cacaagccag cgctattgtt gaaccagagc aagtagcacc actaccagaa tacacagggg
     1801 tacaagccgg atcgatagtc gagccagaga aagtagaagc accgaaagaa tatactggta
     1861 aaatcgaaca acctagtgca gaagatacta aacctgaaaa tgaggcaagc tctacaaatg
     1921 gggaatcgga acgtcctaaa gataaaatta aagaagaaaa acaagtcgac aagaaactag
     1981 aacttagaaa tgtttcaaac gtggaattat atacggtaga aaataataaa tatcgacata
     2041 ttacggctgt agatggtgct ttagatagtt cattgaagta tttcatgaag gtaaaatcag
     2101 aaaattttaa agatataatg ttgcctgtta ctaaaattga aagtacaaca aaaaacaata
     2161 aagaagtata caaaattgtg gctcatgcag aaaatctaat tcaacacgaa aacaatgtta
     2221 tttcgaatga ctatacatat tatttaccaa aaactcagca aagtgaaact ggcgtctata
     2281 catcatttaa aaatttagtt gatgcaatga atagtgaccc taatggaaca ttccatttag
     2341 gtgcaactat ggatgctcgt gaagttgaac ttccggatga tcaagaaagt tatgtaaaaa
     2401 atgaatttta cggaaaatta ataggtgaaa ataatggtaa gtattatgct atttataact
     2461 tgaaaaaacc tttatttaaa actctaaaca ccgctactat tcagaatctt tcaataaaag
     2521 aagcgaatgt ttcttctaaa gaagatgctg ctacaatatc gaaagaagca aaatacaata
     2581 ctcttataga taatgttcat tctgatggta ttatagctgg tgaacgtgga attggtggat
     2641 tggtttcaaa agtagataac tcgagaattt ctaatagtag ttttacaggc agaataacta
     2701 acacatatga tacaactgta gggtatgaaa ttggtggttt agtaggtaaa ctttctggtt
     2761 cgcttgcttc tatagagaaa tcaatagcat cgattgacat agcctctaat gcaaaatcag
     2821 gagatcaaat tgttggtggt atagccggag ttgttgagaa aagtgcgaca attaagtata
     2881 gctatgttga aggaaatgtt aacaatgtgc gacactttgg taaagttggg ggagttgcag
     2941 gtaatctttg ggatagagat tcacaagatg taagtaaatc aggtaaacta tcatatgttt
     3001 taagtgatgt taatgtaaca aatggtaatg ctatatcggg tgataatttt gataatatga
     3061 aagaagatca tgcttatagt agtaaaggca ataaagtagt aaatgtagtc caagtagatg
     3121 atgaacttgt gactaaagat tcagatgtac aaagaggtac ggtattagat gctgataaag
     3181 taaaagagaa aaaggcagaa ttggtttcca aacacagcac taaagtagaa gattttgatt
     3241 tcacttcaag atacactact atttacaatg aagtaacagg ttatcaaaag tcgagagaac
     3301 aagtatataa aaatattgaa aaactattac cgttctataa tcgagagaca attgttaaat
     3361 atggtaattt agtagatgaa agcagcgagc tatttactaa agaacttcta tcagttg
//
LOCUS       DAVMCG010000080         3176 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVMCG010000080 DAVMCG010000000
VERSION     DAVMCG010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.081"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..218
                     /locus_tag="VYP66_002010"
     CDS             <1..218
                     /locus_tag="VYP66_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851494.1"
                     /translation="KFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYL
                     FSVLLLFSNFSVPFIKEKEFELFKNSK"
     gene            1355..1858
                     /locus_tag="VYP66_002011"
     CDS             1355..1858
                     /locus_tag="VYP66_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851495.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQTGVFILEDFRNILLYNDVIERISLYEFISDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            2143..>3176
                     /locus_tag="VYP66_002012"
     CDS             2143..>3176
                     /locus_tag="VYP66_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1851496.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSSPTFVRAEEAPVASQSKAEK
                     DYDAAKKDAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEKKAAAVKKIDEEHQAAN
                     LKSQQALVEFLAAQREGNPKKKKAAQAKLEEAEKAEKEKKKEFDKAQAVVVPEATELA
                     ETKKKADEAKVKEPELTKKLEEAKAKSEEAEKKATEAKQKVDAEHAKEVVPQAKIAEL
                     ENEVQKLEKDLKEIDESDSEDYVKEGLRAPLQSELDAKQAKLSKLEELSDKIDELDAE
                     IAKLEKNVEDFKNSNGEQAEQYRAAAEEDLAAKQAELEKTEADLKKAVNEPETPAPAP
                     KPAPAPAPTP"
BASE COUNT         1157 a          440 c          620 g          959 t
ORIGIN      
        1 taaaattttt attcatcaga ttatttgaca caagtacttt aatgaagagg agaatatttt
       61 ttcttttcgc attggatgtt atagcttact tatttttagg atatctttta gtgattcaaa
      121 aagcaggcta tttgttttcg gttttacttc ttttttctaa tttttcagtt ccatttatca
      181 aagaaaagga attcgaatta tttaaaaata gcaagtaata gaaacatagg ttaaatctta
      241 gaacggctta aaatcagata tgataaaggg aaatagtctt atctaggtaa ctaagtgcta
      301 caaacacagt cgaggatcac ttgttaggat tacattttaa tcatgcttaa taagaatgga
      361 gaattcctat ggggattgta ttactctgaa gtttcgaata ccttagttct cgtgattttg
      421 agctattcta ggtttagaat ccttcagaat gtaaaatttt aagcagtcaa agacttagaa
      481 tagcccgaaa acatttattt tatagcaatt ctaggcttag aattgctcat atatatgtat
      541 ttgagctgct cgatagttag gacagcttta ttctgagaaa tctgagctat caatgcttca
      601 gaatagtatt tcgccaatgg tttttattga agaggtgatt gttttatgat agtctaaaat
      661 aaaactgatt taatggagta aatggagaat cgttacatga aacatttttt tgcaggaatt
      721 ggtgagataa aacttgttgg ctacttattg tatatatgtg taggactagc ccctcttttt
      781 catatatatg tcataggttc ggaactgagt tttgtgaaaa tagtgttatc tattttggga
      841 gttatatttg taagtatgtt aactattgct cgaatttata ggactttttt ctataaagaa
      901 tagtttggac ttgaactgta tctaaaaaca gaggttggtc gattatcagc ctctttcttg
      961 tcgttgaaaa gagtgagata tattgacttt tgaaaaaaag atgtcataat tgagttggga
     1021 taaacctaaa agtaatatag tagattgaat ctggaatagt ccgttatgac tgttaaaata
     1081 tttctagaaa ttaatttgac tttcctaatc gatttgttca catcttgttt caatctacta
     1141 tactttctcg ttaaaccgtt cggcaattca tggtgacatg gacacatggt agtaagcaca
     1201 ctatgtggct tggcagagct aaaaactgtt cccttgcaat aagcctaata agcacaacat
     1261 agggagttag agaagccgac tctaatcaac cactttgggc aatagtgaga actgccctgt
     1321 gcttttttat tttgaaaaaa tatggagttt gtcgttgaaa ttacttgatt gtattttgga
     1381 ctatcaagaa agattcaatg gaaaaacatg tcaagtatca acgaattata agtatttaga
     1441 gattttcaaa gtgaattttt gcttgactga tttacatcat ttatttggct tacacaaaat
     1501 cacacgagat tatgctagtc aaacaaaacc tgctattcaa actggtgttt ttattttaga
     1561 agattttaga aatatcctat tgtacaatga tgtaatcgaa aggatatctt tatatgagtt
     1621 tataagtgat attttctatt ctaaaataac aagttgttgc atcgtagcta aggatttatc
     1681 taaaaatact atgaaattgg acgtcatatt ttttgaggat aaaaataaaa gatccgcagt
     1741 tttaggttta cgaagagata aaagcggagt atttaaacca gttactctac attttacaag
     1801 cgctaagaaa tatgctaaag ttcgtaaaac agatgtgaaa gaaatgaaat ggctataaag
     1861 attgtccgca ggcttaagct tgcgtttttt gttgtttaac gaaattaaaa aataagctct
     1921 ctcatcggaa atgtttttat aggaatgaag gaagatgatg ctatgtttaa aaagagaatc
     1981 gaaaagggca aaagtagtgt ctttatcttt ttggagtaga agcttatgat atagaaattg
     2041 taataaaaat gtaatataaa acatttgaca aatatttacg gagggagtat acttaatata
     2101 agtatagtct aaaaatgact atcagaaaag aggtaaattt agatgaataa gaaaaaaatg
     2161 attttaacaa gtctagccag cgtcgctatc ttaggggctg gttttgttac gtcttcgcct
     2221 acttttgtaa gagcagaaga agctcccgta gctagtcagt ctaaagctga gaaagactat
     2281 gatgcagcga agaaagatgc taagaatgcg aaaaaagcag tagaagatgc tcaaaaggct
     2341 ttagatgacg caaaagctgc tcagaaaaaa tatgacgagg atcagaagaa aactgaaaag
     2401 aaagctgctg cggtaaagaa aattgatgaa gaacatcagg cggctaatct taaatctcag
     2461 caagcattag ttgaattctt agctgctcaa agagaaggta atcctaaaaa gaaaaaagct
     2521 gcgcaagcca agttagaaga agcagaaaaa gcagaaaagg agaagaaaaa ggaatttgat
     2581 aaagcacagg cagtggtagt tcctgaagca actgagttag ctgagactaa gaaaaaagca
     2641 gacgaagcta aagtaaaaga accagaactt actaaaaaac tagaagaagc taaagcaaaa
     2701 tcagaagaag ctgagaaaaa agctactgaa gccaaacaaa aagtggatgc agaacatgct
     2761 aaagaagtcg ttcctcaagc taaaatcgct gagttggaaa atgaagttca gaaactagaa
     2821 aaagatctca aagagattga tgaatctgac tcagaagatt atgttaaaga aggtctccgt
     2881 gctcctcttc aatctgaatt ggatgccaaa caagctaaac tatcaaaact tgaagagttg
     2941 agtgataaga ttgatgagtt agacgctgaa attgcaaaac ttgaaaaaaa tgtagaagat
     3001 ttcaaaaact caaacggtga gcaagctgaa caataccgtg ctgcagctga agaagactta
     3061 gctgctaaac aagctgaatt agaaaaaact gaagctgacc ttaagaaagc agttaatgag
     3121 ccagaaactc cagctccggc tcctaaacca gccccagctc cagctccaac tccaga
//
LOCUS       DAVMCG010000081         3082 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVMCG010000081 DAVMCG010000000
VERSION     DAVMCG010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3082
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.082"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(19..90)
                     /locus_tag="VYP66_002013"
     tRNA            complement(19..90)
                     /locus_tag="VYP66_002013"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(55..57),aa:Glu,seq:ttc)
     gene            complement(152..1507)
                     /gene="rlmD"
                     /locus_tag="VYP66_002014"
     CDS             complement(152..1507)
                     /gene="rlmD"
                     /locus_tag="VYP66_002014"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1851497.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1545..2321
                     /gene="recX"
                     /locus_tag="VYP66_002015"
     CDS             1545..2321
                     /gene="recX"
                     /locus_tag="VYP66_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1851498.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDINENIVSQVIANLKEEKW
                     INDSQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYKGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2410..2943
                     /locus_tag="VYP66_002016"
     CDS             2410..2943
                     /locus_tag="VYP66_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1851499.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT          980 a          571 c          561 g          970 t
ORIGIN      
        1 tcctgacgca acataccata gtccgtacgg gattcgaacc cgtgttaccg ccgtgaaaag
       61 gcggtgtctt aaccccttga ccaacggacc tgagttgtta ttttcaactc ttactattat
      121 acagtctttt caaactttgt caactacttt tttaaacttt ttttattaat tttacaacag
      181 cttcagttcg agctgtatgt gggaacatat cgaccgactg gatataatga agatcataga
      241 cttctactaa gcgtaccaaa tcacgagcca aggtcgaaac attacaagaa atataaacca
      301 ttttttctgg tacataagta agaatagtat ctaataactt atcatccaga cctgtacgtg
      361 gtgggtcaac aatcaaagca tctgctcggt agccttcctt gtaccaacga ggaataatct
      421 cttctgccgt tccagcttca taatgagtat tgtcaaatcc cattctttta gcatttcgct
      481 tggcatcttc aatagcttct ggaataatat ccatacctct gagtgttttt actttctttg
      541 caaaggcaaa tccaatcgtt ccaactccac aataagcgtc aatcaaatgg tcttctttat
      601 caacatccag cgcttttact gcttcgctat agaggacttc tgtttgctca ggatttagtt
      661 gataaaaagc tcgaggggat agtgaaaatt cataattgag tacaccttct tgaatactct
      721 cttgccccca gataatctct gtcttttcac catatatctc actggtttta gctgtatttg
      781 tattaacagc tactgtcaca acttctggga aatctttaac caactctttt accaattgag
      841 ttaaattaag ctggcggttt gtaacaataa taatctgaac ctgtccggtc tttctcgcgc
      901 gtcggaccat aatagtacgg acacctagaa cttttctctc atccgtgatt ggaatctggt
      961 gataagtaag taattctgct aagcgattag caatcacttg ggtttcctta tcttgtacca
     1021 ggcagtcttt caactctact aaatagtgag agttttgtgc atataagccc gccttgacct
     1081 gatttttaaa ttttcgagtc tgaaattgta acttagctct gtaatatttt ggttcctgca
     1141 ttccaatagt tggacgaatt tcataatttt catatcctgc aggagcaaat tttttcagcg
     1201 cttgatgaag taagtccgtc ttgaactcca gctgcttatc ataatgcagg tgcatgattt
     1261 ggcagcctcc gcattcatta taaatagtac aagatggcac aattcgaaat ttagacttct
     1321 tgttgacctt cagtaatttt gcttcaacaa agttgcgtct aatagaagta atctgacaat
     1381 agatatcttc gcctttgaga gctcctggta caaagactaa tgttttttgg taaaagccga
     1441 ttccctcacc gttaattccc atgcgcttga tttttaatgg tattttttgt ttcactttca
     1501 gattcatacc cctatcttat cacattttga gttataatag agctatgaaa atcacaaaac
     1561 ttgaaaagaa aaaaagactc tatctgatgg agcttgataa tggcgacaaa tgctatatca
     1621 ccgaagacac aattgttcgt tttatgttat cgagagataa ggtgataagc gaagaggaat
     1681 tgaaagagat tcaagacttt gctcaatttt cttatggtaa gaatctggcc ctctaccact
     1741 tatcctttaa agcacgtact gaaaaagagg tcagagaata tctgaaaaaa tatgatatta
     1801 atgaaaacat cgtttctcaa gtcattgcta atcttaaaga agagaagtgg attaatgata
     1861 gccagtacgc ttatgctatc atcaatgcca atcaactttc aggagacaag ggaccttatg
     1921 tactgactca gaaattagca caaaaaggaa tttcaaaatc tactatagaa gaaatcttga
     1981 atgattttga tttttcggaa gttgctcaac gtgtagccaa taaactattg aaaaaatatg
     2041 agggaaaact tccagctcgt gccctgcaag ataagattat ccagaacttg actaacaagg
     2101 gcttctctta ttttgatgct aaaattgcct ttgacgaatt ggatagtcaa gttgatgaag
     2161 aaacgactca ggaactcatc ttcaaggaac ttgataagca atatactaag tatgcccgaa
     2221 agtataaagg atacgaactg aagcagcgtt taactcaagt tttagcacga aagggctacg
     2281 atttttcgga tatagcaagc gctcttagag aatatcttta atatttccaa gtgaaattca
     2341 cagattttgg gtaattttat ggtacaatag taaatgataa acttataaat tgtagaaagt
     2401 tggttagtta tgaagcttcc aaaagaaggc gactttatta caattcaaag ttataagcat
     2461 gatgggagtc tccaccgaac ttggcgggac accatggtac taaaaacaac agaaaacgcc
     2521 attattggtg tcaacgatca tacacttgtt accgaaagtg atggtcgtcg ttgggtcact
     2581 cgagaaccgg ctattgttta ctttcacaag aaatattggt ttaatatcat tgccatgatt
     2641 cgtgataatg gaacttctta ctattgcaat atggctagcc cctactatct ggatgaagaa
     2701 gcactgaagt atattgatta cgatttggat gttaaaattt ttacagatgg ggaaaaacgt
     2761 ctcttggacg ttgaagagta cgagcgtcac aaacgcaaaa tgaattattc tgatgacttg
     2821 gactatattt taaaagaaca tgtcaaaatt cttgttgatt ggattaacaa tggacgtggt
     2881 cctttctcag aagcctatgt aaacatttgg tacaagcgct atgtagaact aaagaatcgg
     2941 taaagttgtc aaaggtcagg aacaaaatcc tgaccttttt tggtagtata aaataaattg
     3001 tgtaaacaca aaaaggaata aatctattat agcagagtta caacacatta ctagaaagag
     3061 atttatgcag aattcgtaaa at
//
LOCUS       DAVMCG010000082         2910 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVMCG010000082 DAVMCG010000000
VERSION     DAVMCG010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.083"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            302..1648
                     /gene="gdhA"
                     /locus_tag="VYP66_002017"
     CDS             302..1648
                     /gene="gdhA"
                     /locus_tag="VYP66_002017"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1851500.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            complement(2154..2324)
                     /locus_tag="VYP66_002018"
     CDS             complement(2154..2324)
                     /locus_tag="VYP66_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851501.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2337..>2910)
                     /locus_tag="VYP66_002019"
     CDS             complement(2337..>2910)
                     /locus_tag="VYP66_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1851502.1"
                     /translation="KIPSRLYKIDTGKVLFDGVNINQIDKKILSQNLGVVPQDSFLLN
                     RSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIISEMGSNISGGQRQRIA
                     LARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIIVAHRLSTIKDADVIFV
                     MKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
BASE COUNT          924 a          544 c          486 g          956 t
ORIGIN      
        1 gtataaatat tgctttcctc caaaatggtc atagttttac tggcaaatct aacatatcac
       61 ggataaatta acaagtgatt tctgaattgc taaacatttt cttttcttat agcatacttt
      121 aagattttgt ctttgagaaa gatatttcca agaaaaacgt tcgttttttt atctattttc
      181 aaaaaaacca aaaaactgaa ttgaaagaat ttttagaaaa tttctgtttt ttctttacag
      241 tgaaaaaaaa ttctgctata atgtcttatg taataaaata tgacaataaa aggagaacga
      301 tatgacatct gctaaagaat atatccaaag cgtgtttgaa actgtgaaag ctcgtaacgg
      361 gcacgaggct gaattcctcc aagctgttga agaatttttc aacactttag aacctgtatt
      421 tgaaaaacac cctgagtata tcgaagaaaa tatcttggca cgtattactg agcctgagcg
      481 cgtggtttct ttccgtgttc cttgggttga ccgtgatgga aaaattcaag taaaccgtgg
      541 ttaccgtgtt caattcaact cagctgttgg accatacaaa ggtggacttc gtttccaccc
      601 aactgtaaac caagggatct tgaaattcct cggatttgaa caaatcttta aaaatgtctt
      661 gactggactt cctatcggtg gaggtaaagg tggatcagac ttcgatccta aaggtaaaac
      721 agatgctgaa gtgatgcgct tctgccaaag cttcatgact gaattgcaaa aacacatcgg
      781 accatcactt gacgtacctg ctggtgatat cggtgttggt ggacgtgaaa ttggttacct
      841 ttacggtcaa tacaaacgtc ttaaccaatt tgatgctggt gtcttgactg gtaaacctct
      901 tggatttggt ggtagcttga ttcgtccaga agcaactggt tacggtttgg tttactatac
      961 tgaagaaatg ctcaaagcta acggtaacag ctttgctggt aagaaagtcg ttatttcagg
     1021 ttctggtaac gttgctcaat atgctcttca aaaagcaact gaactcggtg caactgttat
     1081 ttctgtttct gactcaaatg gttatgtcat cgatgaaaat ggtatcgact tcgatctttt
     1141 ggttgatgtt aaagaaaaac gtcgtgctcg tttgactgag tatgcagctg aaaaagcaac
     1201 tgcaacctac cacgaaggta ctgtatggac ttacgctgga aactatgaca ttgctcttcc
     1261 atgtgccact caaaacgaaa tcaacggtga agcagctaaa cgtttggttg ctcaaggcgt
     1321 tatctgtgta tctgaaggtg ccaacatgcc gagcgacctt gatgccatca aagtttacaa
     1381 agaaaatggt atcttctacg gacctgcaaa agctgccaac gctggtggtg tagccgtttc
     1441 agctcttgaa atgagccaaa acagtcttcg cctctcatgg actcgtgaag aagttgatgg
     1501 ccgtctcaaa gacatcatga caaacatctt caacacagct aaaacgactt cagaaacata
     1561 cggtcttgat aaagactacc ttgcaggagc taacattgct gcctttgaaa atgtagcaaa
     1621 tgccatgatt gcacaaggta ttgtttaaga tttatttact caatcctcaa tcactacgat
     1681 tggggatttt tagcttgaat taaaaaattg gaaaatctaa ttaaataaaa tgaaatgaaa
     1741 taaaaactga acaaattgat tgcggaattc aaaccaattt ctaacatatt tctagaaatt
     1801 aatttgactt ttctaatcga tttgttcata tcttatttca atttactata cttacttgac
     1861 cctttttata ctcaatgaaa atcaaagagc aaactaggaa gcgagccgca ggctgtactt
     1921 gagtacggta aagcaaagct gacgtggttt gaagagattt tcaaagagta ttaaacaaaa
     1981 agaaaaaccg ctactcctaa gaatagcgat ttaatcatgt ttttaagcta ctactgtagt
     2041 tgctctatta tttaagtgtt atgaataact tcaatatctt taaagctttt tgttagattt
     2101 ataatttcaa ctatagccat ctctactcct tagtttacag caaaaaatta tgcttaattc
     2161 ttattgtttt tgtaaacaat cagcgaaccc aatactattc cattcaacaa gcctaaagaa
     2221 ataccatatt caactggaaa atctaaaaaa attgcaaaca ctattccaat catcacccct
     2281 agtgaggctg ttgttaaaat tacatattca ttttctttct tcattttctt tacacctcat
     2341 ttcctttttg tatataagct gtagtactct ccaccaagat ccattaagta cttatgattt
     2401 cctgactcaa caatcttacc acctttcatt acaaaaataa catccgcatc cttaatcgtt
     2461 gacaatctat gagctacaat tatttgagta cagccctgac tttgtatata ctttgttatt
     2521 ctttcctcat taatagtgtc taatgcacta gttgcttcat ctaaaattac aatactagga
     2581 ttatttatta atgcacgtgc cagtgctatc cgttgccttt gcccacctga aatatttgac
     2641 cccatctctg agatgatagt attaaatttc atcggcatag ccatgatttc atcatagatt
     2701 tgaactgctt tacaaacttc ctctatcttt tgtgaagtaa cttcgtgctt taaagttata
     2761 ttatcaagaa tacttcggtt caataaaaat gaatcctgtg gaactactcc taaattttga
     2821 cttaatattt ttttatctat ttgattaata tttacaccat caaataaaac ttttcctgta
     2881 tcaatcttat ataatcttga tggtattttt
//
LOCUS       DAVMCG010000083         2883 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVMCG010000083 DAVMCG010000000
VERSION     DAVMCG010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2883
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.084"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(<1..348)
                     /locus_tag="VYP66_002020"
     CDS             complement(<1..348)
                     /locus_tag="VYP66_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851503.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFLNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQ"
     gene            complement(406..1119)
                     /locus_tag="VYP66_002021"
     CDS             complement(406..1119)
                     /locus_tag="VYP66_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1851504.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIGRDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1578..1958)
                     /locus_tag="VYP66_002022"
     CDS             complement(1578..1958)
                     /locus_tag="VYP66_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1851505.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2380..>2883)
                     /locus_tag="VYP66_002023"
     CDS             complement(2380..>2883)
                     /locus_tag="VYP66_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1851506.1"
                     /translation="LYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRN
                     KNGQADTNQTEKPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESEEPQ
                     VETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLL
                     ALLKESK"
BASE COUNT          876 a          568 c          466 g          973 t
ORIGIN      
        1 ttgttcgtag gcatattttg ctacatgatc taggtatata tcaaaaaagt catgaggaaa
       61 atctcccata cagccattac gattcatatt gaggctatat tttcgattag taagataatt
      121 cagaaatata tttcctatta ctctaagatt atctacttgt gaatcccttc tcccaatata
      181 atccccttct ttgactaatg atggagattt ccaagtaaaa attaaatcgc cagagaaatt
      241 tttcttatca aaaaacttaa aaagagattg ataaatacta tttgctaatt gacaagtgtc
      301 agatgtaaat tcataattaa cagcttcatt aaaatcaact tcagacattt caatgtactc
      361 ttcaatagta atattagctt ttttgtagtc attagctcgt ctcctttaaa atgtgatctt
      421 ttcaagaata tttttatcta aacaatccag caagtcttgg taagaataga cttcgtaagt
      481 cggctgggct tgtgtgtgat tttcgaggtg atgaggatta taccagatag tgtcaatccc
      541 cgcattattg ccaccttgaa tgtcggcggt tagagaatct ccaatcatca gcgtcttttc
      601 tttactaaat ccagcaattt gctggccaat cttttcataa aaaagagcat ccggcttttg
      661 agtttgcaac tgttctgaga taaagacttg attgaaataa ggtgctagac cagattgagc
      721 caaacgtcct gtctgaatgg cagtaatgcc atttgtcgca gcatacaagt tataatcacg
      781 cccaatgagg ctgtccaaga gatcatgagc gcccgatagt gtttgtccct gctgggcgag
      841 gtaaaattgg taacgctggg caagaaaact accgtctttt tcttgtccaa aatgagcaaa
      901 taaacgagaa aagcgcgtgt taaccagctc ttgtttactg attttcttca gctccaagtc
      961 tttccagaga gccttgttca taggaacgta ataatcttta taagcctgaa tatccgcaac
     1021 tccttcttct tttagaagtt gggtcaaagc cacatcctca gcagcatcaa aatcaagaag
     1081 agtgtggtcg aggtcgaaga gtagaaattt gtagaacaat ttgaggtttt cctttctgaa
     1141 aattcattaa gaacattata tcataaagca cctcatacaa ttaactaatt taatcactta
     1201 aaaaaaattc gaacactttc tatacaactg acagctcaaa tctttcagaa tagaacaata
     1261 ctaactatcg aacaccctgt cttcataaat acatatgtaa ttctaggcct agaattccta
     1321 taaactaaat gctttcatac tcttccaagt aattgattgc cttaaatttt aatttttgaa
     1381 ggtttctaaa gctagaatag ccccatcaca atcagttttg attgattcac aatttagaaa
     1441 cactatagtt tcactcctgt taaaataaaa aggaactgca taaagcaatc cctttctgat
     1501 tttgaaatca tttacttaac attttatagt tgagataatc aatagcttat ctataaaaag
     1561 agttatagta aaattcctta tttattgatt tcaagctccg ctaactgtat ttgaataact
     1621 gacagttctg caccagcctg aagaagagca gctgcattat aggcaccttc tacaattgga
     1681 accctgttga tgatgatact tttatcactg aaatcagtca ccatttttaa gttcatttta
     1741 gcagaaccta ggtcaaaaaa ggcaagtaaa gtatctgctg gattttcgga aacaacccta
     1801 tctacttgat caaaactcgt tccaattcct ccgccctcgg ttcctcctac ataagtaatc
     1861 ggaacatctt tagctacttt actaatcagt tcaacaacac cttctgcaat gtgtttggaa
     1921 tgtgaaacga taacaagacc aataccaata ctttccatca aaccactcca gtttctaaaa
     1981 tagcagtaaa gagtaatcct gatgagaatg atccaggatc aatatgtcca agaaaccaca
     2041 tgctcctaag acaagagcta acagactggc catcaataat agtattgttc tttttttcat
     2101 cattactcct taactagtgt ttaactgatt aattagccag taaatagttt atctttattt
     2161 acactatctg ttaagatata gtaaaatgaa ataagaacag gacagtcaaa tcgatttcta
     2221 acaatgtttt agaagtagag gtatactatt ctagtttcaa tctactatat tttgcacatt
     2281 ttcatgaaaa aaatgagaac tagaactcac attctgctct catttttcgt tttcccgttc
     2341 tcctatcctg tttttaggag ttagaaaatg ctgctacctt tacttactct cctttaataa
     2401 agccaatagt ttttcagctt ctgccataat agtattgttg tcctgggtgc caaatagtaa
     2461 attatttttt aatcctgtga gagtctcttt ggcattggac ttgataattg gatcctggat
     2521 ttttccaagt aaatcttcag cctctctcag tttttcttca accttttcag tctcgacctg
     2581 aggttcttct gattcctctg gtgattcttc tggttcctct gttggttttg gagactctgg
     2641 tttctcgctt tgcggtttct cttctcgagg ggtttcttcc tcaggttttt ctgtctgagg
     2701 tttctcctcg cttggttttt ccgtttgatt ggtatcagct tgaccatttt tgtttctttg
     2761 aacatggtcg ctagcgttac caaaaccatt atctgaatgc ggacgttcgt ttggatgttc
     2821 gacatagtac ttgacagtcg ccaaaagatc ctcaagagta taccccttag gtgcctcata
     2881 aag
//
LOCUS       DAVMCG010000084         2735 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVMCG010000084 DAVMCG010000000
VERSION     DAVMCG010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.085"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(1..546)
                     /locus_tag="VYP66_002024"
                     /pseudo
     CDS             complement(1..546)
                     /locus_tag="VYP66_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(639..797)
                     /locus_tag="VYP66_002025"
     CDS             complement(639..797)
                     /locus_tag="VYP66_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEV1851507.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(868..1297)
                     /locus_tag="VYP66_002026"
                     /pseudo
     CDS             complement(868..1297)
                     /locus_tag="VYP66_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1392..1832)
                     /locus_tag="VYP66_002027"
     CDS             complement(1392..1832)
                     /locus_tag="VYP66_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1851508.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKASQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHDQCRSGSVVQEFLGDYSGYVHCDILRQ"
     gene            1823..2131
                     /locus_tag="VYP66_002028"
                     /pseudo
     CDS             1823..2131
                     /locus_tag="VYP66_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2286..2609)
                     /gene="tnpB"
                     /locus_tag="VYP66_002029"
     CDS             complement(2286..2609)
                     /gene="tnpB"
                     /locus_tag="VYP66_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1851509.1"
                     /translation="MTIHLSSLGEVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLIWLSTEKDVKALTPEQVDWLMKGFS
                     ITPKI"
BASE COUNT          826 a          570 c          506 g          833 t
ORIGIN      
        1 gccaagattt taccagcttg tctgatattt ctgcgactca ttttgaacaa cttcatatca
       61 tgacaatagt tcacagtgat atccaaagaa acaattctcc cttgacttgt gacaatcgct
      121 tgagccttca tagcgtgaaa tttcttttta ccagaataat tcgctaattc tttttttagg
      181 gcgattgatt tttacttccg tcgcatcaat cattaccgtg tcctcagaac tgagaggagt
      241 tcttgaaatc gtaacaccac tttgaacaag agttacttca acccattggc tccgacggat
      301 taagttgctt tcgtgaatac caaaaacagc cgcaatttgt tcataagttc gatattctcg
      361 cacatattga agagtggcca taagaaggtc ttctagactt aatttaggtt ttcgtccacc
      421 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtcgt
      481 gcgttgaaca ccaacaagac gcttaaatcg tgcatcggtt agttgtttac ttgcttcatc
      541 attcatagaa ctattatacc atattttgtt tcgcaggaag tctattgaaa aatctccaga
      601 ctggagaact cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca
      661 actttagtcc atggtaaata agcctctaaa acctctttgt ttacgagagt ttcctcgttt
      721 ggaagacatt ctagaagata ggatagatat ttctcgctat ttaattgatg acgtttagct
      781 gtttccaaca aactcataat aatagctctt gctttagctc cttcaaaact ttgagaaaat
      841 aaccaccctc gcttttttaa actgagctta ggctaaaaga gtccactgga ctcttttact
      901 ccgtcccata accaatgatt taatggcgcg ttcagctaga ttattggaaa ggaccagatg
      961 tccgtctttc aaaatggtct taaaggtttc ttcatacttg aggctgtatt caattgccct
     1021 tcctagtttt gaacctgcta aaactgactg acgccggcac taagcaaaga agtcttccat
     1081 taagggctgg agatgttctt gacgtttctg tagtcgttca tcagctggca aagcctccca
     1141 gtctctttcc aaggaaaata actgatcaca ataagctaaa cctttagctc ctaaggatga
     1201 tttatccgct tgcttggggg ggcgcttcaa aaaacttcct tctcacatgc gcccaacatc
     1261 caacaagttc agcttcttcc agttgacgat aagcagacga gcggttcgaa gtttaccaag
     1321 cttagcgtcg ccttgctcct aaaccttgga ctgctatcgc ataggcagaa ctagaggact
     1381 aaagtcctaa gttactgccg caaaatatca caatgcacat agccagaata atctcctagg
     1441 aattcttgta ctactgaacc acttcgacac tgatcatggt ggtaaagcgt aatcccttgt
     1501 ttctctgctt tacctgacaa aaaagtccaa tagtaagtca gctgactatc actctctagc
     1561 accctataag aagtttcatc cgcatgaagt aagggctgag tcaatagtct ctctcgcaag
     1621 aggttataaa ggggctccaa atagtattga ctcgccttga tatgccaatt agagatttcc
     1681 ttacgtgtga ttggtaaacc catcctagcc caatcttctt cttggcgata attgggtacc
     1741 ttcagattaa acttctgatg gatggtgtga gcgataatag aagctgagcc aaagttatgc
     1801 gctaaagggg ctttaggaat aggagatttc acaagcttat ccagatgatt atcttttact
     1861 cgttatggac aatgctatat ggcataaatc aagtacctta aagattccga ctaatattgg
     1921 ctttgcattt attcctccat acacaccaga gatgaacccc attgaacaag tgtggaaaga
     1981 gattcgtaaa cgtggattta agaataaagc cttttaaact ttggaagatg tcatgaatca
     2041 actccaagat gttatacaag gactggagaa ggaggtgata aagtccatcg ttaatcggag
     2101 atggactaga atgctttttg aaagcagatg agtataaaaa gaaagtcctc atttcaatag
     2161 aaatcacgac tttctgatgg atttatagta aaatgaaata agaacaggac aaatcgatca
     2221 ggacagtaaa atcgatttct aacaatgttt tagaagcaga ggtgtactat tctagtttca
     2281 atctactata tttttggagt gatagaaaag cccttcataa gccagtctac ttgttctggt
     2341 gtgagagctt tgacatcctt ttctgtactt agccaaatca atctgccgtt ctcaaagcgt
     2401 ttatatagta gccaaaatcc ttgaccatcc cagtaaagga ctttaaagcg gtctttacgt
     2461 ccaccacaaa agagaaagac ttgaccggag aaaggatcca attcaaagtg ggttttaacc
     2521 agataagcca gtgaatcgat tccttgtctc atatcagttt tcccacacac gagatagacc
     2581 tcccctaggc tagatagatg aattgtcata gagcaacacc ttatccaaaa gctgttctac
     2641 catttcgaga ttgagagatt gaaaaaaact tacttcaagc ttgccaatac gaattttaag
     2701 cagaatatca tttctctttt tagaatcaaa acgac
//
LOCUS       DAVMCG010000085         2535 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVMCG010000085 DAVMCG010000000
VERSION     DAVMCG010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.086"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..559
                     /locus_tag="VYP66_002030"
     CDS             <1..559
                     /locus_tag="VYP66_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1851510.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNISIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VYP66_002031"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VYP66_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1851511.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLTFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1484..2029
                     /locus_tag="VYP66_002032"
     CDS             1484..2029
                     /locus_tag="VYP66_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1851512.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2535)
                     /locus_tag="VYP66_002033"
     CDS             complement(1977..>2535)
                     /locus_tag="VYP66_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1851513.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          868 a          362 c          436 g          869 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt tctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagagat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgg
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgat tacaaggagt aaataaatat ctgactttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaacca tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg ccgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtagtca aactgactac
     1441 ctgctatttt tgtgattatg actcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caataaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgagc aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtcct ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacacta agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttattagca taggggaata tcgatataat ggcttcatta
     2221 tgagtggcag gaatatccaa tatggcaact tttccaatag ataatttaaa gctcattaat
     2281 aaagttcctt taggtgaaat gtctattttc tttgatttta atgctaattt agaaatagat
     2341 tctctcgtat tagttacata accagatata ggcatatctg atatagatac ccagggtatt
     2401 tcagttcccc aaaaagtagc ttcactgcgt ggaggagttt ttcctattct gaagttaact
     2461 aggctagcaa atttaatata tctccatgct tctgggattt catatatagg ataagaggtt
     2521 gtttcgtctt tgttc
//
LOCUS       DAVMCG010000086         2435 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVMCG010000086 DAVMCG010000000
VERSION     DAVMCG010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.087"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(148..1623)
                     /locus_tag="VYP66_002034"
     CDS             complement(148..1623)
                     /locus_tag="VYP66_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1851514.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINTIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2358..2435
                     /locus_tag="VYP66_002035"
                     /pseudo
     CDS             2358..2435
                     /locus_tag="VYP66_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          732 a          534 c          444 g          725 t
ORIGIN      
        1 ctgccatttg acgaacaaaa agtgatgtaa tttctgaaat taacacagga ttacctttga
       61 aaaaatggac tttttcaaga gctttttgcc atgctctaaa atcatcgcca aatcatcaaa
      121 ttgaaataag aaatagttta gataaaacta ttgacttttc ttatagtttg tctttctctt
      181 aatgacgttg atgtgattga cctctggatc ttccgtccct tggagggagc aaccacgttc
      241 cttggcaaat tggatatagt cgacaatttc tcgtgtgatg cgttcgccag gagccaagat
      301 agggattcct ggagggtaac acatgacaaa ttccccacag acctgtccaa cagattcgtc
      361 caaggtcaaa ctttttctct ctgaatagaa ggcttcttgc ggagacagca ctaactcggg
      421 ctgaatatat tctcctgcta tcaaatcttt tccatctctt gaatagagtc tcttaatatc
      481 agccagagca ccaaccaagc gctcgatgtc ttggatgcgg tcgccgatgg aaatataggc
      541 caagatattg ccgatatcac caaactcgat ctgaatgtcg tattcgtctc gcaagaggtc
      601 ataaacctcg atacctgtta agcctattcc ctgagtgtaa actgacaact tggttacatc
      661 aaaatcacag accgacacac catctattaa ctcttttgag taagcatagt aaccgccaat
      721 ggtattgatt tcatgacgag cgtactcgga tagctcaatg acttcctcaa acgactcttt
      781 accacgaagg gccaagttgc gacgtgaaat atccaaacta gccatcaata agtaagaggc
      841 agatgtagac tgggtcaggt ttataatctg acgaacgtac tcgggattca tctgctcccc
      901 gattaaaaga agcgaacttt gtgtcaaact cccaccagac ttatgcatgg aaactgctgc
      961 catatcagct cctgcatcca tagcagaaat tggaagttta ccagtgaaat gcaaatgcgc
     1021 tccatgggct tcatctacta aaaccatcat gccagcttca tgagccattt ctgtcaaccc
     1081 ctttaggtct gaacagatgc cgtagtaagt aggattgttg attaggatag ccttagcatc
     1141 tggatggtcc tttatggcct gtgctactcg gtcattttca agacctaaag cgataccaat
     1201 cttaggatct acactcatct cgatatagat gggaatggca ccacatagaa ccaacgcatt
     1261 gatagcagat ttatggacat ttcgtggcag aataatctta tctcctgcct tgcaggttgc
     1321 cagaatcata gtctgcaccg atgaagttgt tccaccaatc attagaaagg catggctagc
     1381 tccaaaagca tctgcagcca gctcctctgc atcacgaata atcgaaatag gatggcctaa
     1441 attatccaag ggtttcatcg aattgacatc aatgcctaca catttttctc ctaagagttc
     1501 gacaagttct ggatttcccc gtccacgctt gtgacctgga acatcaaagg gaacaatcct
     1561 tttcttgcgt aacttcacca aggcctcata aattggggct tggttttgat ctaactcttt
     1621 caaaacatac tcctttcaat atttttagga ccttatgaaa actaaggaac taaaggttga
     1681 ctcatgaaaa aagagcaggt tttcacctgc tctgcaatct tctgacgtgt ttattttggt
     1741 ttctgttgag tatgtctgtt cccgatgttt cctaactctc tagtagcaaa tattacgtac
     1801 tttattgatc gtttcacaag atgacgtgtg ctttcaccac actaaaaatt tatgaattag
     1861 aacaagtgtc ctaacatcaa cttataaaag taggctttta accctatcaa taatgtggct
     1921 tttcaaccac gcttcggcat tcaaccctgc ctgtccgtag gcatttttta ctcgggttta
     1981 tatttgctag aaaacatcat ctcattttct aagctttatt actatatcat gtttttaaga
     2041 acttgtaaag tattttttga taaaaaataa aaatatagta gattgaaact agaatagtac
     2101 acctctgctt ctaaaacatt gttagaaata gattttactg tcctgatcga tttgttctgt
     2161 tcttgtttca ttttactata tgttcgtaaa tgaaagttct ataatgaagt tagccaccca
     2221 gccctcctaa aaattagatg gttcaactag ccgatagctc ttgtaggcat aagaaaacac
     2281 ctctgtgtta tacttgttgt tcaaccacaa acacaagaaa ggcgcagaga tgcaagacca
     2341 ttatactaca aaaggcgaac aaagggaaat caaatagaga aattgcctct ctgcttggaa
     2401 aagttcctca aactatccac actgaaatca agcgt
//
LOCUS       DAVMCG010000087         2005 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVMCG010000087 DAVMCG010000000
VERSION     DAVMCG010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2005
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.088"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            30..1646
                     /locus_tag="VYP66_002036"
     CDS             30..1646
                     /locus_tag="VYP66_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851515.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          711 a          236 c          364 g          694 t
ORIGIN      
        1 aattaaaatt tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa
       61 aatttagttt attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa
      121 ctattaatgc tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat
      181 tgtcaatcta ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa
      241 attatcaggt tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag
      301 acatctctaa ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt
      361 ggctaaataa tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa
      421 taaaaggaat ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat
      481 tgactgtagc caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat
      541 cgaaaatgcg agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta
      601 gtgagactat attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc
      661 ctaagaaaat taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg
      721 tagaaacgtt agcaggtgct attagcttct ttctcaatat tttttttcag atatctctcg
      781 tttttttaac aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa
      841 taggagcact aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct
      901 ctattattgg tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa
      961 ataaaatgaa tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa
     1021 aaaatatttg ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc
     1081 aacgtaatga aaaatattta attttaggtg aaagtggaag cgggaaatct acattattaa
     1141 aattattgaa tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata
     1201 taaaaaaaac ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt
     1261 atttgtttga aggtacgatt agagataata ttttattgga agaaaattat actgatgaag
     1321 aaatactaca gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt
     1381 tagattatta tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta
     1441 ctttagctag agggttaatt agaaataaga aaatagtatt aattgacgag ggaacttctg
     1501 ctatcgatag gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga
     1561 ctgtcattat tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat
     1621 atcaatttcc aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt
     1681 gaagcttatg aggtaattac tgaagagaaa aaagtatcat ttttttatgt agatgaaaaa
     1741 cccttaaggt atctgttatt tgactatata tttctactag ttctagctaa aaaaaatatc
     1801 ccaatcttat gaactgcacc ccaaaagtta gatttattct gtctaacttt tggggtgcag
     1861 ttcattttgc atagttttgg cattcatcct agatatccat ataaaatgtc tgagattgtt
     1921 gaaatgtcta aaaaaatatc agatttaaac gataaaaaag aatttcacaa aaagaactgt
     1981 gagttgaggt ttcaagatag tgttc
//
LOCUS       DAVMCG010000088         1881 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVMCG010000088 DAVMCG010000000
VERSION     DAVMCG010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.089"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            10..303
                     /locus_tag="VYP66_002037"
     CDS             10..303
                     /locus_tag="VYP66_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEV1851516.1"
                     /translation="MEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNKRLIEKGAV
                     FESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKDEIT"
     gene            613..>1881
                     /locus_tag="VYP66_002038"
     CDS             613..>1881
                     /locus_tag="VYP66_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019213953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEV1851517.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEKWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEK
                     KILYYEIYKAKKEVYEEYQKKNIFTKEAFYN"
BASE COUNT          909 a          225 c          311 g          436 t
ORIGIN      
        1 agattaagta ttgaagaaca gattgaaaag aaagaagaaa gcattaagca attacaaaat
       61 caaaaaagac agttgaagaa aaaacttaat gaacaagaaa gaaaagcaag aaacaaaaga
      121 cttatagaaa aaggtgcagt gtttgaaagt atttttgaag aaagtattga tttaacaaaa
      181 gatgaatttt ataagttaat aaaaacgtta aatgatgaag aaataagatt aaacataatg
      241 gaaattttag aagaaagaat agatgataat gtagaaaaat catctaaaga tgaaataaca
      301 taattgtccc ttggttacaa gggcgcaatt atacacccta aagggtgctt gcgtcctgcg
      361 gagtcaaacc cttgcaggga gtaacaacca ttcgcttttt aaaagtcaag ggtaaataaa
      421 ctcgctaagg ctcgcccttg acttttaaaa tttgaaatga aagtaacaat taagccgaca
      481 tactgaaaca acaaaaatta attcagtagt cggctttttt aattctatca tttcaaaacg
      541 ctcattcaca aagaggatat aaaaaaacta ttaagcctcc acctaaaaca acaaagaaag
      601 gaagtgataa aaatggcaga cagttttcat ttttcagtaa acataatatc aagaggaaaa
      661 ggcaaaagtg cagtagcaag tgcagcatat ataagtggag aaaaaataaa aaatgaatgg
      721 gacggagtaa cccatgacta tacaagaaaa gaaaaaatat tagtaaaaaa tataatattg
      781 cctgatcata taccaaaaga atttaatgat aggtctacct tatggaataa agtagaaatg
      841 gcagaaaaaa attctaatgc acaactagca agacaattca taataggact accaaaagag
      901 ttatctttaa gtgaaaataa aaacctggtt gaaagatata taaaagaaaa tttaacatca
      961 caaggaatga tagtagatta tgcaattcat gatgagagtc aagataaaaa tggaaatatc
     1021 cattgtcata taatgaccat aatgcgacca ataaacgaaa aaggagagtt cttagccaag
     1081 tcaaaaaaag aatatatcct agatgaaaaa ggagaaaaag tattaaacaa aaatggaaaa
     1141 ccaaagacaa gaaaagtaga actaacaacc tggaacgata caggcaatgt agaaaaatgg
     1201 agagaaaatt tttcagatct ttgtaacaaa tatttagaaa gagcaggagc agaaaaaaga
     1261 gtagaccata ggagttttaa aagacaaaat tcagattatc taccgacaat ccatttagga
     1321 tcagcagcaa gtgcaatgga aagaaaggga atagaaactg acaagggaaa ctataataga
     1381 gaaataagaa aatataatca acttgtaaaa acaataaaag aagagataaa aacattaaag
     1441 ggttggatag gaaatttatt agataactta tctactgctt atgaaaaatt taaggatata
     1501 gaaagagata aggtaataga caaccctaaa ctttttaatc taacaaatta tctattaact
     1561 tattcagaaa ttcaaaaaga aaaaagtaaa tatctaaaag gatatgcaaa aactaataaa
     1621 gaaaaatatg acttcaaaaa gctaacaagt gcatatagtt atttaagaaa aaacaacata
     1681 gaaaccatag gtcagttaca aacaaaaata gaaactttaa agtctaatag ttataggcta
     1741 aataaaaaag caaagacaat ccataaagaa atggaagatg tagaaaagaa aattctatac
     1801 tatgaaatct acaaagccaa aaaagaagtt tatgaagaat atcaaaagaa aaatatattc
     1861 acaaaagaag cattttataa c
//
LOCUS       DAVMCG010000089         1863 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVMCG010000089 DAVMCG010000000
VERSION     DAVMCG010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.090"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(14..1021)
                     /locus_tag="VYP66_002039"
     CDS             complement(14..1021)
                     /locus_tag="VYP66_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1851518.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFAKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(1021..1848)
                     /locus_tag="VYP66_002040"
     CDS             complement(1021..1848)
                     /locus_tag="VYP66_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1851519.1"
                     /translation="MPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGASLS
                     VVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSMAL
                     SSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLNAL
                     AMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISKDI
                     RTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVNN"
BASE COUNT          679 a          334 c          272 g          578 t
ORIGIN      
        1 cacagacctt tcattatata ttcctcctgt tcatttttat tagtaagtat attaagtatg
       61 gtgaacctaa caagccagtt acaacaccta ctggatatct agctggtaaa atattttgag
      121 agaatatgtc tgataacaaa actagtaaaa ttccaaccaa tccagctaat attgggcttc
      181 ttttcttgcc aatatttaag gctatgggac cagctaaaaa agatatacaa gctattggtc
      241 ctgtaattga agtagaaaaa gcagttaaag atacagcgca aaaaattaaa acaagccttg
      301 aaagctcggg atttgctcca agtccgattg ctatttcttc accaagttca ataatttcta
      361 gtcttttatt aaaaaataaa actaatatag tagcaataat acttactatt agaacaagag
      421 gtatgtcatc taactttgca aaagataaag agccactgag ccatctcata acttcttgta
      481 attcatatct tgctactttc aacaataaaa atgaggtgcc tgctcttgtg acagcttgaa
      541 aaccaatacc taatattatc agtcttgctg ctgaaaaacc atctttttta gctagtaaaa
      601 ataatattaa agatgatgtt agtccacaag ttattgaaat aattccagta gttaaactat
      661 ttgtttttaa taccaatatg caaaagaccg ctgcaataga tgaagaactt gtgacaccga
      721 ttatatcagg acttgcaaga ggatttctta acatagtttg aaagataaat cctgccaatc
      781 caaaagacca gccagctata attcctgcta ataattttgg taatctaatt tccataatcg
      841 aaaaactagc tccaggaaca gtttcactat ttaagacttt aatcaaagtt gaaaaagaat
      901 aactttcatc tccgataagt aaaatgaaaa atgatagact gattattatt aataaaaata
      961 gtgaggaaaa tagtgttatt ctattttttc ttttttgaat acctataatt aaattttgca
     1021 ttagttatta acccctctat ttttcatagt tacataaata agtactggac ccccgattat
     1081 tgcagtaatt atccctactt caatttcacc tggtttacct aacatacggc cgattatatc
     1141 acatataagc aagagctctg cacctataaa agatgaagaa atggtcattg tgcgtatatc
     1201 tttgcttata aataagccac aaaagtgagg aactataaga cctacgaagc caataggtcc
     1261 accaattgca gtaatacttg aacataaaag cacacttgca attattgcaa gtgatcttat
     1321 cctattaaca ttaactccaa gaccaacagc catttcatca cccatagcta aagcgtttaa
     1381 atctgatgaa ataaatatag ctatcaagtg acctaaaatt ataaaaggta gtagtgtaga
     1441 tatagaagat aatgtagctg ctccaaggct acctatttgc caaaatctaa atttgtctaa
     1501 gacgttatta ttcggtaaaa ttaaaaaact tacaaaactg cttaaagcca tactaacaca
     1561 agttcctgat aaggcaagtt ttataggggt aaggcctgct tttccgctta cagcaatcgc
     1621 gtatacaaaa attgcactta ctaagccacc aatgattgca aaacttatat ggcttatgct
     1681 tgatgaaatt cctaaaaaag aaagaccaat tactacacta agacttgctc ctgtgtttat
     1741 accgagtata cctggatcag ctattgggtt tctagtaact gattgcatca atacaccgct
     1801 tatggcaaga ctagaacctg ctaaaattgc aaaaatagtt ctaggtattc ttttatatat
     1861 aat
//
LOCUS       DAVMCG010000090         1642 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVMCG010000090 DAVMCG010000000
VERSION     DAVMCG010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.091"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            77..484
                     /locus_tag="VYP66_002041"
     CDS             77..484
                     /locus_tag="VYP66_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1851520.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            649..948
                     /locus_tag="VYP66_002042"
     CDS             649..948
                     /locus_tag="VYP66_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1851521.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1209..1532
                     /gene="tnpB"
                     /locus_tag="VYP66_002043"
     CDS             1209..1532
                     /gene="tnpB"
                     /locus_tag="VYP66_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEV1851522.1"
                     /translation="MMILLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKYRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          555 a          325 c          290 g          472 t
ORIGIN      
        1 taataacgat actagataat gaggaaaatg caatggcaaa cccaactttc ggagaaaaaa
       61 agcgaataca gactatattg ctcgctatgg cgtatatgca gttatcccta atcctgaaca
      121 aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg ttcctaccat gtggagaaat
      181 tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag ttgattgaag agcttggttt
      241 cacagcagaa attggtacct attacggaca agctgacgaa tatttctatt ctcgtcatcg
      301 tgatacctac tactacaatc ctgcctacct ctatgaagca acttctttca aagaagtaca
      361 aaagccacta gaaaacttta atcatattgc ctggttccct attgacgagg ctatccaaaa
      421 ccttaaacgt ggtagccata aatgggccat tgaatcttgg aaaaaacagc ataagattgg
      481 ctaatactct tcgaaaataa aattcaaacc acgtcagcgt cgccttaccg tactcaagta
      541 tagcctgcgg ctatcttcct agtttgctct ttgattttca ttgagtataa atcaagcgac
      601 tttattcaaa aagtgctata atagaattag aaaatcggag gaaatattat gaagcttatc
      661 aatacgacaa actcacactc gcaactggta aaaagtcagc tagaaagtac cgatgcaacc
      721 cttgttgagg tttattctgc agggaataca gatgttattt ttacccaagc tccgcttcac
      781 tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg agcctgaaat cgaaaccatt
      841 caagaatttt tcttgaaacg taaaattgat aagacctctg ttgatgaagc caatatcaag
      901 acactctact cagagaaatt aattggaatt tcaatcccaa tcaagtaaga aaattgagta
      961 aaaactcgat ttgagagaaa gtccaataag tctttccata acaaaacgca tagtaacaag
     1021 agtttctaca cccactatta tacgttttta tcattttgaa atctgctgct aatcaatgaa
     1081 gaagcaaaga tcaaactagg cagctagtta caagttacgt aagcgcgtca taacaaggta
     1141 tctatcctaa ttccccaact tccagtatac tagataaaaa ataattatca gaggaaaggt
     1201 attgtactat gatgattcta ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga
     1261 cagatatgag gcagggaata gactcattag cctatgtagt taaaacccac tttgaattgg
     1321 atcctttctc cggtcaagtc tttctctttt gtggtggacg taaataccgc tttaaagccc
     1381 tctactggga tggtcaagga ttttggctac tatataaacg ctttgagaac ggcagactga
     1441 cttggcccag tacagaaaag gatgtcaaag ctctcacatc tgaacaagta gactggctta
     1501 tgaagggctt ttctatcact ccccaaatat agtggattta aactagaata gtacacctct
     1561 acttctaaaa cattgttaga aatcaatttg actgtcctga tcgatttgta ctgttcttat
     1621 ttcattttac tatagaacga tt
//
LOCUS       DAVMCG010000091         1502 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVMCG010000091 DAVMCG010000000
VERSION     DAVMCG010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1502
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.092"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            85..>1502
                     /gene="pcpA"
                     /locus_tag="VYP66_002044"
     CDS             85..>1502
                     /gene="pcpA"
                     /locus_tag="VYP66_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1851523.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLW"
BASE COUNT          590 a          203 c          242 g          467 t
ORIGIN      
        1 tgattgaata aaacttttta taacaacggc tagcaaagtt ataattttat atctattaga
       61 aaataaatat gtaaggaaat ttaaatgaaa aaaactacaa tattatcatt aactacagct
      121 gcggttattt tagcagcata tgtccctaat gaaccaatcc tagcagatac tcctagttcg
      181 gaagtaatca aagagactaa agttggaagt attattcaac aaaataatat caaatataag
      241 gttctaactg tagaaggtaa cataggaact gttcaagtgg gtaatggagt tactcctgta
      301 gagtttgaag ctggtcaaga tggaaaacca ttcacgattc ctacaaaaat cacagtaggt
      361 gataaagtat ttaccgttac tgaagtagct agtcaagctt ttagttatta tccagatgaa
      421 acaggtagaa ttgtctacta tcctagctct attactatcc catcaagcat aaaaaaaata
      481 caaaaaaaag gcttccatgg aagtaaagct aaaactatta tttttgacaa aggcagtcag
      541 ctggagaaaa ttgaagatag agcttttgat ttttctgaat tagaagagat tgaattgcct
      601 gcatctctag aatatattgg aacaagtgca ttttctttta gtcaaaaatt gaaaaagcta
      661 accttttcct caagttcaaa attagaatta atatcacatg aggcttttgc taatttatca
      721 aatttagaga aactaacatt accaaaatcg gttaaaacat taggaagtaa tctatttaga
      781 ctcactacta gcttaaaaca tgttgatgtt gaagaaggaa atgaatcgtt tgcctcagtt
      841 gatggtgttt tgttttcaaa agataaaacc caattaattt attatccaag tcaaaaaaat
      901 gacgaaagtt ataaaacgcc taaggagaca aaagaacttg catcatattc gtttaataaa
      961 aattcttact tgaaaaaact cgaattgaat gaaggtttag aaaaaatcgg tacttttgca
     1021 tttgcagatg cgattaaact tgaagaaatt agcttaccaa atagtttaga aactattgaa
     1081 cgtttagcct tttacggtaa tttagaatta aaagaactta tattaccaga taatgttaaa
     1141 aattttggta aacacgttat gaacggttta ccaaaattaa aaagtttaac aattggtaat
     1201 aatatcaact cattgccgtc cttcttccta agtggcgtct tagattcatt aaaggaaatt
     1261 catattaaga ataaaagtac agagttttct gtgaaaaaag atacatttgc aattcctgaa
     1321 actgttaagt tctatgtaac atcagaacat ataaaagatg ttcttaaatc aaatttatct
     1381 actagtaatg atatcattgt tgaaaaagta gataatataa aacaagaaac tgatgtagct
     1441 aaacctaaaa agaattctaa tcagggagta gttggttggg ttaaagacaa aggtttatgg
     1501 ta
//
LOCUS       DAVMCG010000092         1397 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVMCG010000092 DAVMCG010000000
VERSION     DAVMCG010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.093"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>1397
                     /locus_tag="VYP66_002045"
     CDS             <1..>1397
                     /locus_tag="VYP66_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1851524.1"
                     /translation="KILDISDKVKNTELYLDEQFVKTKANIKDTLSKLLSADAAIAEN
                     SNSIIDNYVIQKIKQNKEALLLGLTYLERWYNFKYGETKAKDLVMYHLDFFGKSNSSA
                     LDNVIQLGKSGFNNLLAKNNVITYNVLLSKNYGTESLFKALEGYRKVFLPTTSNNEWF
                     KAQTKAYIVEEKSSIPEVSKKQSEQGTKYSIGIYDRLTSPSWKYQSMVLPLLTLPEEK
                     TVFMIANISTIGFGAYDRYRSKVHPKGDNLNKFVEDNVREAAKRFRDHYDYWYKILEP
                     ENREKLYRSLLVYDAFKFGRDNTEDKVTYQADFETDHPAIKYFFGPAGNNVVHNGHGA
                     YATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRSGLGPEFYAKGLLQA
                     PDHPYDPTITINSVLKYDDSENSTRLQVADPTQRFNSAEDLHNYMHNMFDLIYTLEIL
                     EGRAVAKLDYNAKND"
BASE COUNT          551 a          173 c          242 g          431 t
ORIGIN      
        1 gaaaatatta gatatctcag ataaagttaa aaatacggaa ttatacttag atgagcaatt
       61 tgttaaaaca aaagcaaata taaaagatac tttatcaaaa cttctgtcag cggatgcagc
      121 aatcgctgag aatagtaatt cgataattga taattatgtt attcagaaaa tcaaacagaa
      181 taaagaagct ttattgttag gattaacata cttagagcgt tggtacaatt ttaaatatgg
      241 tgaaacgaaa gcaaaagatt tagttatgta tcacttggat ttcttcggta aatctaatag
      301 ttctgcatta gataatgtta ttcaattagg taaatctgga tttaacaatt tactagcaaa
      361 aaataatgta attacttaca atgtattatt atctaaaaat tatggaactg aaagtttatt
      421 taaagcatta gaaggatata gaaaagtatt cttaccaaca acttctaaca atgagtggtt
      481 taaagctcaa actaaagcat atattgttga agaaaaatct tctattccag aagtaagtaa
      541 aaaacaatca gaacaaggaa ctaagtattc tataggaatt tatgatagat taactagtcc
      601 gtcatggaaa tatcaaagta tggtcttacc actattaact ttacctgaag aaaaaacagt
      661 atttatgata gcgaatattt caacaatagg atttggtgct tatgatagat atagaagtaa
      721 agtccatcct aaaggagata acttaaataa atttgtagaa gacaatgtaa gagaagctgc
      781 aaaaagattt agagatcatt atgattattg gtataaaata ttagagcctg agaatagaga
      841 gaaactttat agaagtttat tagtatacga tgcatttaaa tttggtcgag ataatactga
      901 agataaagta acttatcaag ctgattttga aactgatcat ccagctataa aatacttctt
      961 tggacctgcg gggaataatg ttgttcataa tggacacgga gcatatgcta ccggagatgc
     1021 attctattat atggcatatc gtatgttgga taaagatgga gctgtaacat atactcatga
     1081 aatgacacat aactctgata gagaaattta tcttggagga tatggaagaa gaagcggatt
     1141 agggcctgag ttttatgcta agggcttatt acaagcacct gaccacccat atgatccaac
     1201 aataacaatt aactctgtgt tgaaatatga tgattcagaa aattcaacaa gacttcaagt
     1261 agctgatcca actcaacgat ttaatagtgc agaagaccta cataattata tgcataatat
     1321 gtttgattta atatatactc ttgaaatatt agaaggtcgt gctgtagcta aattagatta
     1381 taatgcgaaa aatgatt
//
LOCUS       DAVMCG010000093         1361 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVMCG010000093 DAVMCG010000000
VERSION     DAVMCG010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.094"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..611
                     /locus_tag="VYP66_002046"
     CDS             <1..611
                     /locus_tag="VYP66_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HEV1851525.1"
                     /translation="KTIVIDFTTSRIDCVEKFKKTVEIKGGYYIEAPFTGGKLGSNSG
                     QLSIFLHIDEGVNYNKKELMELLKLISKKIYFFEKSTEPTKFKLIYNSWGAYLLYSIK
                     LFNPLQYDFSPKSLEVANTIVCNDGWMSLVCNSKLEQINDQDFDDIHFRVEYMVKDLE
                     YANFSVFHDEVKEINYLLQQYRDCLVTDSGKDYTVIGKYDNL"
     gene            598..1320
                     /locus_tag="VYP66_002047"
     CDS             598..1320
                     /locus_tag="VYP66_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1851526.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
BASE COUNT          522 a          144 c          243 g          452 t
ORIGIN      
        1 gtaaaaccat agtaattgat tttacaacct ccaggattga ttgcgttgaa aaatttaaaa
       61 aaactgttga aattaaaggg ggatactata tagaggctcc tttcacagga ggtaagttag
      121 gaagtaatag tggtcaacta tcaatttttt tacatattga tgaaggtgta aactataata
      181 aaaaggagtt aatggaatta ttaaaattaa tttcaaaaaa aatatacttt tttgaaaaga
      241 gtacggaacc aacaaaattc aagttaattt ataactcgtg gggagcgtat ttgctttact
      301 ctattaagct attcaaccct ttacagtatg atttttcacc aaagtctcta gaggtagcga
      361 atacaatcgt atgtaatgat ggttggatga gtttagtatg caactccaaa ttagaacaga
      421 tcaatgatca agattttgat gacatacact ttagagtaga atatatggta aaagatttag
      481 aatatgctaa tttttcagtc tttcatgatg aagtgaaaga aataaattat ttattacagc
      541 aatataggga ttgcttagta actgatagtg gaaaagatta tacggtaata ggaaagtatg
      601 ataacttata ggaatgactt gctgtctaaa gaattagata tactaatttc attttttaaa
      661 aaatgcgagg taggaaaaat ttcactcgtt attactggtt ccttggcaag aggtaatcca
      721 agaatcaagg atgggaaatt agaatcggat attgatattc tagttatagt agacagtatt
      781 cagcaattaa ttagtataaa aaagacttta gagggaaggt ttcactttgt acataaaatt
      841 tctttgattt tttgtttgaa ggaaagaata aatcgaagtc gttatcgtgg aattattaat
      901 agtattagaa gtgtagataa tcttttagta gataatctgc atataaaaaa tcaaataata
      961 gaagctttag actcacctac caatattgtg gagcagactc gctctatgat tcaggaattt
     1021 tgttattatt catcaaaata tttaatttca aagaataatt atttggaatt aaaactagaa
     1081 aagtattgga aggagattgc aacattaaat catatcgata aaaagataaa acacctagat
     1141 tttgaaagaa tatttgctgt tttaaaagaa cacaaaatac aaattttgga ttcaagtgaa
     1201 tattttttcc aaaatgtaaa aacttctgag aatatttatt tagagatgag ggatttagta
     1261 tctttggaaa atcaaggatt agactttgaa cattgtattt tgagcttggg ggaaagatga
     1321 taataaatac attaggacca actgcaacag attgtttttt a
//
LOCUS       DAVMCG010000094         1261 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVMCG010000094 DAVMCG010000000
VERSION     DAVMCG010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1261
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.095"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..739
                     /locus_tag="VYP66_002048"
     CDS             <1..739
                     /locus_tag="VYP66_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1851527.1"
                     /translation="ENINIKIPEEKISVIIGSNGCGKSTLIKTLSRLIKPLEGEVLLD
                     NKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGRFPYRKPFKSLGKDDLEIIN
                     RSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSILLLDEPTTYLDISYQIELL
                     DLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKLVAEGKPEDILNDKLVKDIF
                     NLEAKIIRDPISNSPLMIPIGKHHVSS"
BASE COUNT          521 a          196 c          200 g          344 t
ORIGIN      
        1 ggaaaatata aatataaaaa tacctgaaga aaaaatatca gttattattg ggtcaaatgg
       61 ttgtgggaaa tcaacactca ttaaaacctt gtctcgactt ataaagccat tagagggaga
      121 agtattgctt gataataaat caattaattc ttataaagaa aaagatttag caaaacacat
      181 agctatatta cctcaatctc caataatccc tgaatcaata acagtagctg atcttgtaag
      241 ccgtggtcgt ttcccctaca gaaagccttt taagagtctt ggaaaagatg accttgaaat
      301 aataaacaga tcaatggtta aggccaatgt tgaagatcta gcaaataacc tagttgaaga
      361 actttctggg ggtcaaaggc aaagagtatg gatagctcta gccctagccc aagatacaag
      421 tatcctactt ttagatgagc caactactta cttggatatc tcatatcaaa tagaactatt
      481 agacctcttg actgatctaa accaaaaata taagacaacc atttgcatga ttttgcacga
      541 tataaatcta acagcaagat acgctgatta cctatttgca attaaagaag gtaaacttgt
      601 tgcagaggga aagcctgaag atatactaaa tgataaacta gttaaagata tctttaatct
      661 tgaagcaaaa attatacgtg accctatttc caattcgcct ctaatgattc ctattggcaa
      721 gcaccatgtt agctcttaat aattgaatat cggaattcat ttaaaagtcg caaattttga
      781 actgaccctc aaaagttagg ccaaaaaact aactaaagga ggtcagtttt ttaatggcaa
      841 atacagcaca gaatttaaga taaaattagt aaaagaatat catgaatgaa aaataggata
      901 tagataataa cagcaatatt aaaaagatca ggactgataa taaacaaaaa gaaagtacaa
      961 cgactagttc aaaagctaaa acttcaagta aaaagttatt caagaaaatc tagaaaatac
     1021 tcatcctaca aaggacaggt aggaaaaata tcagacaaca aaataaaaag aaatatttat
     1081 taccgaaaaa aaggggaaat cgagtcaagt accaacaggc tcatctattc caaaaagata
     1141 tttactcgat ggaaaaactc ctagaattag tgctacaaat attgacaatg gtatcttagg
     1201 ttactacgaa gatatagatg ataaaaatta tagagttttt gaaaatttta tatctgtttc
     1261 a
//
LOCUS       DAVMCG010000095         1149 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVMCG010000095 DAVMCG010000000
VERSION     DAVMCG010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.096"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            13..1038
                     /locus_tag="VYP66_002049"
     CDS             13..1038
                     /locus_tag="VYP66_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1851528.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1028..>1149
                     /locus_tag="VYP66_002050"
     CDS             1028..>1149
                     /locus_tag="VYP66_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1851529.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLA"
BASE COUNT          447 a          159 c          192 g          351 t
ORIGIN      
        1 taaggagttt ttatgaaaaa caaatttttt ctaatagcta ttttagctat gtgtatagtt
       61 tttagcgctt gttcttctaa ttctgttaaa aatgaagaaa atacttctaa agagcatgcg
      121 cctgataaaa tagttttaga tcatgctttc ggtcaaacta tattagataa aaaacctgaa
      181 agagttgcaa ctattgcttg gggaaatcat gatgtagcat tagctttagg aatagttcct
      241 gttggatttt caaaagcaaa ttacggtgta agtgctgata aaggagtttt accatggaca
      301 gaagaaaaaa tcaaagaact aaatggtaaa gctaacctat ttgacgattt ggatggactt
      361 aactttgaag caatatcaaa ttctaaacca gatgttatct tagcaggtta ttctggtata
      421 actaaagaag attatgacac tctatcaaaa attgctcctg tagcagcata caaatctaaa
      481 ccttggcaaa ctttatggag agatatgatt aaaattgatt caaaagcctt aggtatggaa
      541 aaagaaggtg atgagttaat caaaaatact gaagctcgta tatccaaaga attagaaaaa
      601 catccagaaa tcaaaggaaa aatcaaagga aaaaaagtat tatttactat gattaatgct
      661 gcagatacat caaaattctg gatttatact agcaaagatc caagagcaaa ttatttaaca
      721 gatttaggtc tagttttccc tgaatcatta aaagaatttg agagtgaaga tagttttgca
      781 aaggaaattt ctgcagaaga agcaaataag ataaatgatg ctgatgtaat cataacttat
      841 ggtgatgata aaactcttga agctttacaa aaagatcctc ttttaggtaa aataaatgca
      901 attaaaaatg gtgccgttgc tgtaattcca gataatacac cgttagcagc ctcatgcact
      961 ccaacaccac tttcaataaa ctatactatt gaagaatacc taaatctttt aggaaatgca
     1021 tgcaaaaatg cgaaataaaa aacaaataaa cctaggcata atttttgtaa tctgcctagg
     1081 tcttcttatt acaatatttt tgtcattaaa gcttggaaca aaagaaatta atatcagaga
     1141 ttttttagc
//
LOCUS       DAVMCG010000096         1093 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVMCG010000096 DAVMCG010000000
VERSION     DAVMCG010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.097"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            2..730
                     /locus_tag="VYP66_002051"
     CDS             2..730
                     /locus_tag="VYP66_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1851530.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
BASE COUNT          363 a          173 c          192 g          365 t
ORIGIN      
        1 aatgagtaca aaatatttat ttatttacaa tgagattcgt gaaaagattc tttgtaataa
       61 atataccatg aacgaacaat tacctgatga aatgacatta gctaaacagt ttgcctgtag
      121 tcgaatgacg atcaaaaaag ctttagactt gttagtttct gagggcttaa tttttagaaa
      181 acgtgggcag ggaacctttg ttctctctcg tggcagctca aaaagaaaat taatcgttcc
      241 agaaagagat atccggggac tgacaaaaat atctgaagat gctcattcta caattgactc
      301 gaggattatt cacttcaaat tagaatttgc aaatgaattt ttagcagaaa aactacaggt
      361 cgctttgcag agtccagttt ataatattta ccgcctgcgt attattgacg gtaaacctta
      421 tgttctggaa caaacttata tgagtaccga tgttattcca ggtattactg aagatatttt
      481 acaaaaatcg atttacaatt acattgaagg aaagttagga ttgcatattg ccagtgctac
      541 aaaaatctta cgagcttctt ctagttcaga aaatgagcaa cattacttgc agctccttcc
      601 aacggaaccg gtatttgaag tagaacaagt ggcttatttg gataacggaa ctccgtttga
      661 gtactcgatt agtcgtcatc gctatgattt atttgaattt aattcttttg cattacgaca
      721 ttcctcctag gagaaaatgt gaaaatgaag ccaatctttt acagactcta gtttaagaaa
      781 aatttaaaac agggcaagaa ggtcccatct atgcttaaat ggtttctctt ttctaaataa
      841 gatggcttta aaagagtgat cgttttatcc atcatgttga aaaatatctt cgtatagctt
      901 atagagtagg tactgaaatt gttcacctga tctacttctt atagttattt agttttaaat
      961 agtgtttcaa atattcttac actgacgaga agtttttgag tcttttcttg taacacatat
     1021 agtatactga ggttagaata gtagactgtg acttctaaca aattgctaga aatgaatttc
     1081 aatctcccaa ttt
//
LOCUS       DAVMCG010000097         1066 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVMCG010000097 DAVMCG010000000
VERSION     DAVMCG010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.098"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            1..1066
                     /locus_tag="VYP66_002052"
                     /pseudo
     CDS             1..1066
                     /locus_tag="VYP66_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          326 a          240 c          180 g          320 t
ORIGIN      
        1 tcaaatgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg aaacgactgg
       61 tatgccttct agaattctcc ttagaaaacg ccgtttcaag tgctatcact gttcaaaaat
      121 gatggttgct gagactcccc tggtaaagaa aaatcaccaa atccctcgta tcatcaacca
      181 aaaaattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc atcagctttc
      241 catctcaact tcaactgtca ttcgcaagct caatgattct cactttgagc atgatttttc
      301 gcgtcttcct gagattatgt cctgggacgt tgaaacagtc cggggagtga ctgtttcaat
      361 cgggagatgg agatgagctt cattgcgcaa gattttaaca atctcaatat catcactgtt
      421 cttgagggaa gaacacaagc tatcattcga aatcactttc ttcgctacga tagagctgtc
      481 cgatgtcgcg tcaaaattat tactatggat atgtttagcc cttactatga cttggctaaa
      541 cagcttcgct ttcaaatttc taggctcagg ctgaaacagt ctcccagact gtttcactcc
      601 cgaatgctaa aatcgttctt gatcgctttc acattgtgca acatcttagc cgtgctatga
      661 gtcgtgtgcg tgttcaaatc atgaatcagt ttcatcgaaa atcccatgaa tacaaggcta
      721 tcaagcgcta ctggaagccc atacaacagg atagccgtaa actgagtgat aagcgatttt
      781 atcgtcctac ttttcgtatg catttaacca ataaagagat tttagacaag cttttgagct
      841 attcacaaga cttgaaacac cactatcagc tctatcagct cttgctgttt cacttccaga
      901 ataaggaacc agagaaattt ttcggactta ttgaggacaa tcttaagcag gctcatccta
      961 tttttcagac tgtctttaaa accttcctca aagataaaga aaagattatc aacgcccttc
     1021 aactacacta ttctaatgcc aaactggaag cgaccaataa tctcat
//
LOCUS       DAVMCG010000098          899 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVMCG010000098 DAVMCG010000000
VERSION     DAVMCG010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.099"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>899
                     /gene="phtD"
                     /locus_tag="VYP66_002053"
     CDS             <1..>899
                     /gene="phtD"
                     /locus_tag="VYP66_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEV1851531.1"
                     /translation="PEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRKVGD
                     GYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKA
                     YDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERL
                     GKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKD
                     SLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYN
                     LQYTVEVKNGSLIIPHYDHYHNI"
BASE COUNT          300 a          191 c          190 g          218 t
ORIGIN      
        1 ccagaacaac caagtccaca atcgactccg gaacctagtc caagtctgca acctgcacca
       61 aatcctcaac cagctccaag caatccaatt gatgagaaat tggtcaaaga agctgttcga
      121 aaagtaggcg atggttatgt ctttgaggag aatggagttt ctcgttatat cccagccaag
      181 gatctttcag cagaaacagc agcaggcatt gatagcaaac tggccaagca ggaaagttta
      241 tctcataagc taggagctaa gaaaactgac ctcccatcta gtgatcgaga attttacaat
      301 aaggcttatg acttactagc aagaattcac caagatttac ttgataataa aggtcgacaa
      361 gttgattttg aggctttgga taacctgttg gaacgactca aggatgtctc aagtgataaa
      421 gtcaagttag tggatgatat tcttgccttc ttagctccga ttcgtcatcc agaacgttta
      481 ggaaaaccaa atgcgcaaat tacctacact gatgatgaga ttcaagtagc caagttggca
      541 ggcaagtaca caacagaaga cggttatatc tttgatcctc gtgatataac cagtgatgag
      601 ggggatgcct atgtaactcc acatatgacc catagccact ggattaaaaa agatagtttg
      661 tctgaagctg agagagcggc agcccaggct tatgctaaag agaaaggttt gacccctcct
      721 tcgacagacc atcaggattc aggaaatact gaggcaaaag gagcagaagc tatctacaac
      781 cgcgtgaaag cagctaagaa ggtgccactt gatcgtatgc cttacaatct tcaatatact
      841 gtagaagtca aaaacggtag tttaatcata cctcattatg accattacca taacatcaa
//
LOCUS       DAVMCG010000099          813 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVMCG010000099 DAVMCG010000000
VERSION     DAVMCG010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.100"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(169..240)
                     /locus_tag="VYP66_002054"
     CDS             complement(169..240)
                     /locus_tag="VYP66_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HEV1851532.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            322..>813
                     /locus_tag="VYP66_002055"
     CDS             322..>813
                     /locus_tag="VYP66_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEV1851533.1"
                     /translation="MKSKLGITLRKVRKGKQISLCSVADEHLSKSQISRFERGESEIS
                     CIRLINILDKLHITLDEFLILHDEDYTKTESFANLIQYIRKQYSLQNINNIQSLLSDS
                     SNYTLDSFEKTMVKSILHTMDSRIIPSDDELLQLADYLFKVEKWGYYEIILLGNCVRT
                     INYN"
BASE COUNT          296 a          135 c          105 g          277 t
ORIGIN      
        1 aggattttta atataccccg agtcattata ccatacccta taattaatac ttttttatgt
       61 ttcaaagtct caccactctc taaaatttta cgatttaact taaatatgtt ttagctagta
      121 agtatagtct ttagatactc taaagactta ggtgtacacc taagtgattt aaccaccaac
      181 aataatgata atgtccatca ctagcatcaa aattgggaaa aattttgaaa ttttcttcat
      241 atttagactt cctttcaatt tttatttatt gtacaataaa taaaactaag ttaacttttt
      301 gttgggagaa tgggaaaaac tatgaaatca aaacttggca tcacacttag aaaagttcgt
      361 aaaggcaaac aaatcagtct atgctctgtt gctgatgagc atctttcaaa atcgcaaata
      421 tcccgatttg aacgtggaga gtcagagata tcatgtatcc gactgatcaa tattttagac
      481 aaattacaca ttactttgga tgagtttctt attttacacg atgaagacta tacaaaaact
      541 gagtcatttg ccaacttaat acagtatatc cgtaaacaat attcattaca aaacatcaat
      601 aatatacaat ctctactttc ggattcctca aattacactt tagattcttt tgaaaaaaca
      661 atggtaaaat ccattttaca cacaatggat tcaagaatca ttccatcaga tgatgaatta
      721 cttcaactag cagattatct ctttaaagtt gaaaaatggg gttattatga gattatttta
      781 ttaggtaact gtgtacgaac aattaactac aac
//
LOCUS       DAVMCG010000100          740 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVMCG010000100 DAVMCG010000000
VERSION     DAVMCG010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.101"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            256..327
                     /locus_tag="VYP66_002056"
     tRNA            256..327
                     /locus_tag="VYP66_002056"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:289..291,aa:Glu,seq:ttc)
     gene            579..>740
                     /locus_tag="VYP66_002057"
     rRNA            579..>740
                     /locus_tag="VYP66_002057"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          274 a          119 c          177 g          170 t
ORIGIN      
        1 tatctctttc atgaaacact aagagattat agaaacaaac aaagtaaaga gaaacaagaa
       61 gaactagaac gcgtcttaag caatgaacga tttcgagggc gtcaaagagt attaagagac
      121 ttacgcattg tgtttaagga gtttactatc cgtacccact agtaagtcat gcaaaaaaaa
      181 tgaaaaaaat tagaaaaagt agttgacaaa gtttgaaaag actgtataat agtaagagtt
      241 gaaaataaca actcaggtcc gttggtcaag gggttaagac accgcctttt cacggcggta
      301 acacgggttc gaatcccgta cggactatgg tatgttgcgg ttggaacact tgatgaaaaa
      361 aagtttaaaa aagcttaaaa atcttcaaaa aagtgttgac aagcgaaagc ggctgtgata
      421 tactaatata gttgtcgctt gagagaagca agtgacaaag acctttgaaa actgaacaag
      481 acgaaccaat gtgcagggcg ctacaacata agttgtagta ctgaacaatg aaaaaacaat
      541 aaatctgtca gtgacagaaa tgagtaagaa ctcaaacttt taatgagagt ttgatcctgg
      601 ctcaggacga acgctggcgg cgtgcctaat acatgcaagt agaacgctga aggaggagct
      661 tgcttctctg gatgagttgc gaacgggtga gtaacgcgta ggtaacctgc ctggtagcgg
      721 gggataacta ttggaaacga
//
LOCUS       DAVMCG010000101          711 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVMCG010000101 DAVMCG010000000
VERSION     DAVMCG010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.102"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>711
                     /locus_tag="VYP66_002058"
     CDS             <1..>711
                     /locus_tag="VYP66_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1851534.1"
                     /translation="STLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNV
                     KEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDY
                     LFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLSEQQRIVEAIESALEKV
                     DEYAESYNRLEQLDKKFPDKLKKSILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKL
                     FEEGKIKKKDLDISIVSQ"
BASE COUNT          278 a           97 c          118 g          218 t
ORIGIN      
        1 tttctacatt ggttgaaatt gtcagaggtg gctctccacg accaatcaaa gattatctta
       61 cttctgaagt agatggaata aattggataa aaataggtga tactgaaaag ggtgaaaagt
      121 atataaataa tgttaaagaa aaaatcaaaa aatcagggct taacaaaact agatttgtaa
      181 aaaaaggtac atttttgtta actaattcta tgagttttgg tagaccttat attttgaatg
      241 ttgatggtgc aatacacgat ggatggttgg ctatttcgaa ctatgaaaac tcattaaata
      301 aagattatct attctatatt ctttcatcaa atgtagttta ttctcaattt ctatctctaa
      361 ttagtggagc tgttgtgaaa aacttgaata gtgataaagt tgcttctatt cttatccctc
      421 tccctccact atccgaacaa caacgaatag tagaagcaat cgaatcagct ttagaaaaag
      481 tagatgaata tgctgaaagt tataatagac tagaacagct agataaaaaa tttccagata
      541 aactaaaaaa atctattctt caatatgcta tgcaaggaaa attagttgaa caagacccaa
      601 atgatgaatc agtcgaagtt ttacttgaaa aaatacgagc agaaaaacaa aaactctttg
      661 aagaaggcaa gattaaaaag aaagatttgg acatttctat tgtttcccaa g
//
LOCUS       DAVMCG010000102          686 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVMCG010000102 DAVMCG010000000
VERSION     DAVMCG010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.103"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            83..445
                     /locus_tag="VYP66_002059"
     CDS             83..445
                     /locus_tag="VYP66_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1851535.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKTISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
BASE COUNT          228 a           86 c          126 g          246 t
ORIGIN      
        1 atctacaacc tcaaaacagt gttttgagca acctgaggct agtttcctag tttgctcttt
       61 ggttttcatt gagtataaca gattgttaga agttggttta aatttcctaa tcagtttgtt
      121 cacatttacc ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag
      181 tcatggagcc gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaacaatatc
      241 tgtaactgta ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata
      301 cgtaaatggt actgctattc tttatcatta tttacgttct attgtttcaa tagtttcggc
      361 aattgatagc agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa
      421 atctcaacct tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt
      481 aaaagcagta agaaaaatgt cttgcattat acagcaacct tttgggaatg agtagatgga
      541 ttgaataaaa ttttattaag agtggatgat ttatctgtag attattattg gacagttagt
      601 cttgaagtag tctaagaatt aggttataat cagtagaatc cttgctaata atgaggaggt
      661 tagtttatgt atagtagact gaatct
//
LOCUS       DAVMCG010000103          675 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVMCG010000103 DAVMCG010000000
VERSION     DAVMCG010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.104"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>675
                     /locus_tag="VYP66_002060"
     CDS             <1..>675
                     /locus_tag="VYP66_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M26"
                     /protein_id="HEV1851536.1"
                     /translation="YATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGY
                     YTIDLFSPIYSALSGEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAG
                     SKIKSYGKEVGLVTDKLVLEKVFNNRYSSWVEFKKAMYNERIAKFNNLISVSFNNPNV
                     SWGRTNRITITSIANLQNMINTAVNEDAEDFRAQLYPDTNSRVLKLKKAIYKAYLDQT
                     NDFRRSI"
BASE COUNT          269 a           79 c          125 g          202 t
ORIGIN      
        1 tatgcgacaa atgttgttcg cagattaacg atggatgaag ttaataaatt aaattctttt
       61 gatagtttaa ttgaaaatga tattattact agcagagggt acaaagacca agaatataag
      121 agaaatggtt attatacaat tgatttattt tcaccgattt attcagctct tagtggagag
      181 aaagggactc ctggtgattt aatgggacgt cgtatagcat tcgaattatt agctgcaaaa
      241 ggatataaag agggcatggt accttatatc tcaaatcaat atgaaaaaga tgcaaaagct
      301 gcgggaagta agattaaatc ttatggtaaa gaagtaggtt tagttacaga taaattagta
      361 cttgaaaagg tatttaataa tcgttactca tcttgggtag aatttaaaaa agcaatgtat
      421 aatgagcgaa tagctaaatt taataatcta ataagtgtta gctttaataa tccaaatgta
      481 agttggggaa gaactaatag aataacaata actagcatag ccaaccttca aaatatgata
      541 aatacggctg tcaatgaaga tgctgaagat tttagagcac aattataccc tgatacaaat
      601 agtagagttc ttaaactgaa aaaagcaata tataaagcct atcttgacca aacaaatgat
      661 tttagaagat caatt
//
LOCUS       DAVMCG010000104          670 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVMCG010000104 DAVMCG010000000
VERSION     DAVMCG010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.105"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            8..670
                     /locus_tag="VYP66_002061"
                     /pseudo
     CDS             8..670
                     /locus_tag="VYP66_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833783.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
BASE COUNT          258 a           67 c          124 g          221 t
ORIGIN      
        1 tagagctgtg aaaagttgtt tacatcaaaa ttataaaaat atcgaagtta taattattga
       61 tgataattat agtaatgtaa atttaagaaa taaaattatc catcaatttg gctataccaa
      121 tcatagaatt aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat
      181 aggtatcaaa aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat
      241 gccagatcga attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc
      301 tttagtttat agttatggaa taataattta tccaaatggt acacgagaag aggagaagac
      361 cgattttgtt ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt
      421 ttggttgtgt aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca
      481 tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg
      541 agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca
      601 aaaaaacaat taatgcagat gaagaatatt ataattactg taggaaatat tttaatttat
      661 tgagtttcaa
//
LOCUS       DAVMCG010000105          652 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVMCG010000105 DAVMCG010000000
VERSION     DAVMCG010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.106"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..625
                     /locus_tag="VYP66_002062"
     CDS             <1..625
                     /locus_tag="VYP66_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1851537.1"
                     /translation="KVPYLKEGGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGS
                     NGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFTDEVFNE
                     LRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDE
                     PSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFEL"
BASE COUNT          253 a           74 c          124 g          201 t
ORIGIN      
        1 aaaagttcct tatttaaaag aaggtggaga gtatcagata aaaaatctta gctacaaatt
       61 tactgatgat gagtgtttaa gcttaaaaga tatttcgttc aagcttggga aaatttatgg
      121 cataatagga tccaacggac gaggaaaatc aacgctttta agatgtttaa taggtcttga
      181 gaaaaaatca aaagaagaaa tttattttaa gggagagaag ctatctaaaa aagaaagact
      241 caaaaactct tcacttgtta tgcaagatgt aaatcatcaa ttattcacag atgaagtatt
      301 caacgagctt agattaggag taaagaattt tgatgaagaa aaggcgaaaa tcattttaaa
      361 agatttaggc ctggacgaat ttattgaaag gcatccgatg agtttatcag gagggcaaaa
      421 gcaaaggctt gcaatagcat ctgttatgtg caagaattct ccatttgtct tttttgacga
      481 accttcaagt ggtatggatt attccaatat gataaaaata tctgaactga ttaataagta
      541 taaaaccatg gataaaataa tttttattgt ttcccatgat atagaatttt taaatgaagt
      601 ggcagatgaa atttttgaat tgtaaaatag agtctgttaa acatgtctat ag
//
LOCUS       DAVMCG010000106          553 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVMCG010000106 DAVMCG010000000
VERSION     DAVMCG010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.107"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..367
                     /locus_tag="VYP66_002063"
     CDS             <1..367
                     /locus_tag="VYP66_002063"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851538.1"
                     /translation="SSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINR
                     AIIQPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDI
                     IICETFSPEMIWCLYRVKG"
BASE COUNT          202 a           54 c          108 g          189 t
ORIGIN      
        1 gagtagtatt aaaaattata gttggaaaga tttcaacttt gaatatcata agcggattga
       61 aattgtggat tcttttcact cttttactaa gggaatggtt ctaatcgaga attgtaatta
      121 taaaattaat agggcgatta tccaacctgc aactgagatt ttgatgttaa actatttaaa
      181 gaaaaaaagt atggatctga ggatagattt tacccatagt aaagttatgg caaataaaaa
      241 atttctggaa gaaggttatc gtttttcaat agtaagtcaa gaaacgataa ttaataatga
      301 tgatattatt atttgtgaaa ctttctctcc agaaatgatt tggtgcttat atagagtgaa
      361 aggatagaaa atgttttctg aaattattaa gaaatatgat attgttacac tgaaagatag
      421 tggttttttg agaggtgatt ggttcatagg ttcagcgtta atggctcatg actatgaaag
      481 ccttaaggaa gggatatatt tctatcccca ggaaacaatt tggacaagaa tcttggattt
      541 agaatatata aat
//
LOCUS       DAVMCG010000107          516 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVMCG010000107 DAVMCG010000000
VERSION     DAVMCG010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.108"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            complement(63..>516)
                     /locus_tag="VYP66_002064"
     CDS             complement(63..>516)
                     /locus_tag="VYP66_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851539.1"
                     /translation="KIPLCIGEDYFNFPVVSYVSNPYSLIRGFYLGFHKELDCNYVFD
                     DAELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNSNLVNQYGKYTLLDID
                     KYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIKNMEVN"
BASE COUNT          182 a           90 c           60 g          184 t
ORIGIN      
        1 agtccaaaac tgtatgtgat cctatgtatc ctgctccacc tgttattaat aatgatttca
       61 tgctaattta cctccatatt ctttatacca ttaatttgaa atttatcttg gctaaaaatt
      121 accctatttg attttgcttc acttccaaga aagttaccga tagaaatttc tggaaattca
      181 aaaatctttc tagactctaa tttatatttg tctatgtcta acaaagtata ttttccatat
      241 tgattaacca gattggaatt attaaacaag atcaagggat agttatactc ccttggtaat
      301 tctgctgtaa tgattgaatt ttgattttta aattcgaagt taaattcaca aatcccttcc
      361 ctaaaaaaat gaagctctgc atcatcaaat acatagttac agtccaattc cttatgaaaa
      421 cctagataaa atcctcttat taacgaatag ggatttgaaa catatgatac aaccggaaaa
      481 ttaaaataat cttctccaat acaaagaggt atctta
//
LOCUS       DAVMCG010000108          474 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVMCG010000108 DAVMCG010000000
VERSION     DAVMCG010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.109"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            253..465
                     /locus_tag="VYP66_002065"
     CDS             253..465
                     /locus_tag="VYP66_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851540.1"
                     /translation="MDERFLDHAIINQIDVTSEQIVLMSDGFYEFYQNNQNKTFEELI
                     KMRFNSSAIDPIYGKKDDASILVIDV"
BASE COUNT          180 a           47 c           85 g          162 t
ORIGIN      
        1 tatcgcttac caatatttgc ttttatattt gctaaacttt cagaaaaaaa gttggagtat
       61 atgatgctag gtgactgcgt catgttagta aacgaaatgg aaataactga tcatagagta
      121 gataacttat ttgaaaaagg gaaaaatgag ataaaagatt caattggtac aaatagtgtt
      181 ttaaataaaa aaattatttt acaaaaaatc agaaaattat ctaatcaacc gagtgggtac
      241 tggataggtt cgttggatga gagattttta gaccatgcta ttattaatca aatagatgtt
      301 actagtgaac aaattgtttt aatgagcgat ggcttttatg aattctatca aaataatcaa
      361 aataaaactt ttgaagagtt aattaagatg agatttaatt cttctgctat tgatccaatc
      421 tatggaaaga aggatgatgc aagtattcta gtcattgatg tttgatatat tgtt
//
LOCUS       DAVMCG010000109          406 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVMCG010000109 DAVMCG010000000
VERSION     DAVMCG010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.denovo.110"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            <1..>406
                     /locus_tag="VYP66_002066"
     CDS             <1..>406
                     /locus_tag="VYP66_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HEV1851541.1"
                     /translation="KSIYWNFGQNKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQA
                     PSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLL
                     SDNFINRVNNKSTGTSYPAINDYNFNLLLIALP"
BASE COUNT          151 a           59 c           54 g          142 t
ORIGIN      
        1 taaaatcaat ttattggaat tttgggcaaa ataagccaga gaaatccttt aggtatatag
       61 atacgtctag tattgataga aaaaagaaca taatcaacta caaaaatcta caatatcttt
      121 cacctgaaca agcgccttcc cgtgctagaa aattagtttc gcagaatagt gtcttatttt
      181 caacagttag accatatcta aaaaatattg ctgtagttag agaacttaaa gagtatttga
      241 tagctagtac agcatttatt gttttggata ctttacttaa cgaaacatat ttgaaatatt
      301 atttattatc agataatttt atcaatcgtg ttaataataa atctactgga acaagttatc
      361 ctgcaatcaa tgattataat tttaatctat tattaattgc tctccc
//
LOCUS       DAVMCG010000110        28972 bp    DNA     linear   BCT 22-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00021575
            SAMN33607295-rid17947443.guided.022, whole genome shotgun sequence.
ACCESSION   DAVMCG010000110 DAVMCG010000000
VERSION     DAVMCG010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607295
            Sequence Read Archive: SRR23725413
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721290.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721290.1
            Genome Coverage       :: 182x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:30:25
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,101
            CDSs (total)                      :: 2,054
            Genes (coding)                    :: 1,944
            CDSs (with protein)               :: 1,944
            Genes (RNA)                       :: 47
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 2 (5S, 16S)
            tRNAs                             :: 39
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 110
            CDSs (without protein)            :: 110
            Pseudo Genes (ambiguous residues) :: 0 of 110
            Pseudo Genes (frameshifted)       :: 55 of 110
            Pseudo Genes (incomplete)         :: 55 of 110
            Pseudo Genes (internal stop)      :: 31 of 110
            Pseudo Genes (multiple problems)  :: 24 of 110
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28972
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607295-rid17947443.guided.022"
                     /strain="AUSMDU00021575"
                     /serotype="33A"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2018"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST717"
     gene            371..607
                     /locus_tag="VYP66_002067"
     CDS             371..607
                     /locus_tag="VYP66_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1851542.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            838..2124
                     /locus_tag="VYP66_002068"
     CDS             838..2124
                     /locus_tag="VYP66_002068"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1851543.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            2325..2792
                     /locus_tag="VYP66_002069"
     CDS             2325..2792
                     /locus_tag="VYP66_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1851544.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            2825..2918
                     /gene="ffs"
                     /locus_tag="VYP66_002070"
     ncRNA           2825..2918
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VYP66_002070"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            2978..3421
                     /locus_tag="VYP66_002071"
     CDS             2978..3421
                     /locus_tag="VYP66_002071"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1851545.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAAGGVRTGGFGSTGH"
     gene            3423..3938
                     /locus_tag="VYP66_002072"
     CDS             3423..3938
                     /locus_tag="VYP66_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1851546.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            3952..5313
                     /gene="radA"
                     /locus_tag="VYP66_002073"
     CDS             3952..5313
                     /gene="radA"
                     /locus_tag="VYP66_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1851547.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLQQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            5386..5883
                     /locus_tag="VYP66_002074"
     CDS             5386..5883
                     /locus_tag="VYP66_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1851548.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            5908..6117
                     /locus_tag="VYP66_002075"
     CDS             5908..6117
                     /locus_tag="VYP66_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851549.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            6099..6722
                     /locus_tag="VYP66_002076"
     CDS             6099..6722
                     /locus_tag="VYP66_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1851550.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            7123..7437
                     /locus_tag="VYP66_002077"
     CDS             7123..7437
                     /locus_tag="VYP66_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1851551.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            7453..7839
                     /locus_tag="VYP66_002078"
     CDS             7453..7839
                     /locus_tag="VYP66_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HEV1851552.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            7868..9253
                     /locus_tag="VYP66_002079"
     CDS             7868..9253
                     /locus_tag="VYP66_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1851553.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            9256..9408
                     /locus_tag="VYP66_002080"
     CDS             9256..9408
                     /locus_tag="VYP66_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1851554.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            9431..10849
                     /locus_tag="VYP66_002081"
     CDS             9431..10849
                     /locus_tag="VYP66_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HEV1851555.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKKGYLSTIPVDRYPKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMEI
                     RLRSKLKSVLIVHYLKILYNRN"
     gene            10898..10981
                     /locus_tag="VYP66_002082"
     CDS             10898..10981
                     /locus_tag="VYP66_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HEV1851556.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            11106..11843
                     /gene="erm(B)"
                     /locus_tag="VYP66_002083"
     CDS             11106..11843
                     /gene="erm(B)"
                     /locus_tag="VYP66_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HEV1851557.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTITYEQVLSIFNSYLLFNGRK"
     gene            complement(12100..13347)
                     /locus_tag="VYP66_002084"
     CDS             complement(12100..13347)
                     /locus_tag="VYP66_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1851558.1"
                     /translation="MSHNDSILNILGIKDKNIKIISVEEAEHNNDSVKEYITLITATL
                     SYPINRCRNCGFPTVNKDGFRKTHVRLASLNGRRYELELRKQRYKCKSCHTTFGAITN
                     LTKENQTLSSDLKNQIMLLARKGLSGQLIAEMCHCSPSSVRRTILERMEPHYRVAKLP
                     KHLCFDEFRSIKSVMSFICCDAETHQIVTKLQDRLSPTIVDYFESRYSKAERECVQSV
                     VIDLNAQYQSFIYRLFPNANIIIDRFHLVQLAGRALDNCRISILKQLDKQSQEYKIMK
                     SHWKLFHKKAEDLHPEEVVFLRGVKQYMTRQNAVDLITSKFSKFAEVYQTYQDITKAL
                     NERNSELLESTILDYQKTNTEMDTAIQTLRQNRKYVLNSAKFEYSNGPLEGINRKIKT
                     LKRTCYGFANQKFFFLRIDCIFS"
     gene            13527..13748
                     /locus_tag="VYP66_002085"
     CDS             13527..13748
                     /locus_tag="VYP66_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1851559.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            13865..14362
                     /locus_tag="VYP66_002086"
     CDS             13865..14362
                     /locus_tag="VYP66_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HEV1851560.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            14337..14843
                     /locus_tag="VYP66_002087"
     CDS             14337..14843
                     /locus_tag="VYP66_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1851561.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAGKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            14827..17274
                     /locus_tag="VYP66_002088"
     CDS             14827..17274
                     /locus_tag="VYP66_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1851562.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            17277..19454
                     /locus_tag="VYP66_002089"
     CDS             17277..19454
                     /locus_tag="VYP66_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1851563.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            19451..20452
                     /locus_tag="VYP66_002090"
     CDS             19451..20452
                     /locus_tag="VYP66_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HEV1851564.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            20449..21381
                     /locus_tag="VYP66_002091"
     CDS             20449..21381
                     /locus_tag="VYP66_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEV1851565.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            21626..21742
                     /locus_tag="VYP66_002092"
     CDS             21626..21742
                     /locus_tag="VYP66_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HEV1851566.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            21758..23677
                     /gene="tet(M)"
                     /locus_tag="VYP66_002093"
     CDS             21758..23677
                     /gene="tet(M)"
                     /locus_tag="VYP66_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HEV1851567.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            23796..23963
                     /locus_tag="VYP66_002094"
     CDS             23796..23963
                     /locus_tag="VYP66_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HEV1851568.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(24023..24376)
                     /locus_tag="VYP66_002095"
     CDS             complement(24023..24376)
                     /locus_tag="VYP66_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1851569.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            24881..25303
                     /locus_tag="VYP66_002096"
     CDS             24881..25303
                     /locus_tag="VYP66_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1851570.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            25300..25530
                     /locus_tag="VYP66_002097"
     CDS             25300..25530
                     /locus_tag="VYP66_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1851571.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            25991..26194
                     /locus_tag="VYP66_002098"
     CDS             25991..26194
                     /locus_tag="VYP66_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HEV1851572.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            26276..27493
                     /locus_tag="VYP66_002099"
     CDS             26276..27493
                     /locus_tag="VYP66_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1851573.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            27755..28723
                     /locus_tag="VYP66_002100"
     CDS             27755..28723
                     /locus_tag="VYP66_002100"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1851574.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(28860..28972)
                     /locus_tag="VYP66_002101"
                     /pseudo
     CDS             complement(28860..28972)
                     /locus_tag="VYP66_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9153 a         4979 c         6227 g         8613 t
ORIGIN      
        1 tgatacaagg aatttgatga ttcttcttga cgatagaagt ttcagcgacc ctcatttttg
       61 aacagtgata gcacttaaaa cggccttttc taagaagaat tctagtttga attttttata
      121 ctagaaaatc agaaccataa tacctatata aaaatattat agttctaata ggatttaccc
      181 aaaagtttta aggcggtctt tttagaactt taatcgtttg aaatttaggt agcaaatttg
      241 tttctattct gtcaactttt cctattttta tcttgttgag cctggtattt taacaattca
      301 ggaattgata gtgaatgtgt aaaatttttt gttagaataa gtttataaaa aagaaaagga
      361 gtatttgatt atgttacaaa aaatttatga gcagatggct aatttctatg atagtattga
      421 agaagagtat ggtcctacat ttggtgataa ttttgactgg gaacatgttc attttaaatt
      481 tttaatttat tatttagtga gatatggcat tggttgtcgt agggatttta tcgtttacca
      541 ttatcgtgtt gcttatcgtt tgtatcttga aaaattggta atgaatcggg gttttatttc
      601 ttgttgaggt aattttagta aatttccgaa ctaatttact cttttatgga aagatgatag
      661 taaatagcta gtaatttttc taaatcattt tttaatagtt ggaaatagca aatctttcta
      721 ttgtttcttc ttgataaaaa ggcgattttt tattataata aattgtaaga tataattgca
      781 ggtgagagtc ctgccatgta tgtgagaaag gaagagcctg agggctcaga caagattatg
      841 acttcagttg ttgttgtagg tacccaatgg ggtgatgaag gtaaagggaa gattacagac
      901 ttcctttcag cgaatgcaga agtgattgca cgttaccaag gtggtgataa tgctggtcac
      961 acgattgtga ttgacggtaa gaaatttaag ttgcacttga ttccatctgg gattttcttc
     1021 cctgaaaaaa tatctgtcat tgggaatggt atggttgtaa atcctaaatc tcttgtaaaa
     1081 gagttgagct atcttcatga ggaaggtgta acaactgata acttgcgtat ttctgatcgt
     1141 gcgcatgtta ttttgcctta tcatatcgag ttggatcgct tgcaagaaga agctaagggc
     1201 gacaataaga ttggtacgac aattaaggga attggtccag cttatatgga caaggctgct
     1261 cgtgttggaa ttcgtattgc agatctttta gataaagata ttttccgtga gcgtttagaa
     1321 cgtaaccttg ctgaaaagaa tcgtcttttt gaaaaattgt atgacagtaa agcgattgtt
     1381 ttcgatgata tttttgaaga atattacgaa tatggtcaac aaatcaagaa atacgtgata
     1441 gatacatctg ttatcttgaa tgatgcgctt gataatggca aacgtgtgct ttttgaaggt
     1501 gcacaaggtg ttatgctaga tatcgaccaa ggtacttatc catttgttac gtcatcaaac
     1561 cctgtagctg gtggtgtgac aattggttct ggtgtcggtc caagcaagat tgacaaggtt
     1621 gtaggtgtat gtaaagctta tacgagtcgt gtaggagatg gtcctttccc aactgagttg
     1681 tttgatgaag tgggagaacg tatccgtgaa gtgggtcatg agtatggtac aacaactggt
     1741 cgtccacgtc gtgtaggttg gtttgactca gttgtgatgc gtcatagccg tcgtgtttct
     1801 ggtattacta acctttcttt gaactctatt gatgttttga gcggtttgga tactgtgaaa
     1861 atctgtgtgg cctatgatct tgacggtcaa cgtattgact actatccagc tagtcttgag
     1921 caattgaaac gttgcaagcc tatctatgaa gagttgccag gttggtcaga agatattacc
     1981 ggagttcgca atttggaaga tcttcctgag aatgcgcgta actatgttcg tcgtgtgagt
     2041 gaattggttg gcgttcgtat ttctactttc tcagtaggtc ctggtcgtga acaaacaaat
     2101 attttagaaa gtgtttggtc ctaagagatt tttaagattt gtttaagata ggtcgggtat
     2161 actatagacg gttacaagaa gacctcctaa cttgttgtaa caaatatcct aaacttttct
     2221 ttttcataat aatctcccta tagagtcacc gcattcggtg gctttttttg tgttgggatt
     2281 catgatataa taataaaatc gataagtagg aaaagagaaa agagatgtat tatacgcttg
     2341 aagaaaaaga agtctttatg agggaggctt tgagagaggc tgagattgct cttgaacacg
     2401 atgaaattcc aattggttgt gtgattgtca aagatgggga aatcattggt cgtgggcata
     2461 atgcgcgtga ggaattacag cgagcggtta tgcatgcgga aattatggct atagaggatg
     2521 cgaacttgag tgaggagagc tggcgcttgc tggattgcac actttttgtg accattgaac
     2581 cttgtgtcat gtgtagtgga gcgattgggc ttgcccgcat tccaaatgtg gtctatgggg
     2641 ctaaaaacca gaaatttggc gctgctggga gtttgtacaa tatcttgaca gatgagcgtc
     2701 tcaatcatcg tgtggaggtt gaaataggaa ttttggaaga tgaatgcgca gctatcatgc
     2761 aggatttttt tagaaataga cggaaaaaat aattttgctt ttaaaatgaa taggaatgtg
     2821 atataataaa tagtggagca acagttctgc gtgaagcggg tcaggggagg aatccagcag
     2881 ccctaagcga tttgaattgt gtgctctttt ttcgtgcttt ttccgaataa ataagataga
     2941 ataatctaga ataaatgata atagaaaaga gaaaattatg aaaattcgtg gttttgaatt
     3001 ggtttcaagt tttacagatg aaaatttatt gcccaagcgt gagacagcgc atgcggctgg
     3061 ttacgactta aaggttgctg tgcgtacagt tgttgcgcca ggagagattg tcttggttcc
     3121 gacaggggtt aaggcttata tgcagccgac tgaggttctc tacctctatg atcgttcttc
     3181 aaatcctcgt aagaagggct tggttttaat taactcagtt ggggtcattg atggggatta
     3241 ttatggaaat cctggaaatg aagggcatat ttttgcgcag atgaagaata tcacagacca
     3301 agaggttgtt cttgaagttg gggaacgtat tgtccaggct gtttttgcta ctttcttaat
     3361 tgcagatgga gatgcagctg gtggcgttcg aactggtgga tttggatcga cagggcacta
     3421 gaatgaagat tatctttgta cgtcatgggg agccagatta ccgtgagtta gaggagcgtt
     3481 cttatatagg atttgggata gatttggcac ccttgtctga gatgggacgg cagcaagtcc
     3541 agaaattgag caaaaatcct ttactctcgt cagctgaaat aatcgtatct tctgcagtca
     3601 caagagcttt agaaacggct tcgtatgtgg tctgtgctac gggtcttcct ttaagagtag
     3661 agcctttatt acatgaatgg caggtctata aaacaggaat agaaaacttt gaaacagcta
     3721 gaagactgtt tttagaaaac aagggggagt tgcttcctaa tagtcctatt caatatgaga
     3781 cagctacgga aatgaagtct cggtttctag aatgtatgtc taagtatcga gaacatcaga
     3841 ctgtggtagt tgttgctcat cgaatgctca tgcgccagtt tgtgccaaat gagaagattg
     3901 atttttgcca agtgattgag tgtgagttag agatatagga agaggtttgt catcgcaaag
     3961 aaaaaagcga catttgtatg tcaaaattgt gggtataatt cccctaaata tctgggacgt
     4021 tgccccaact gtggatcttg gtcttctttt gtggaagagg ttgaggttgc cgaggtcaag
     4081 aatgcgcgtg tgtccttgac aggtgagaaa accaagccca tgaaactagc tgaggtgact
     4141 tccatcaatg tcaatcgaac caagacggag atggaggaat tcaaccgtgt gcttggaggc
     4201 ggagtggtac caggaagtct cgtcctcatc ggtggggatc ctgggattgg gaaatcaact
     4261 cttctccaac aagtctcaac ccagttgtcc caagtgggga cagttctcta tgtcagtggg
     4321 gaggagtctg cccagcagat taaactacgt gcagagcgct taggtgatat tgatagtgag
     4381 ttttatctct atgcagagac caatatgcag agtgttcgtg cagaagtgga gcgtatccag
     4441 ccagactttc ttattattga ttccatccag accatcatgt ctcctgagat ttcaggggtg
     4501 caggggtctg tttctcaggt acgtgaagtg accgctgaac tcatgcagtt ggccaagacc
     4561 aataacattg ccatctttat cgtaggtcat gtgaccaaag aaggaacctt ggctgggcct
     4621 cgtatgttgg agcatatggt ggatacggtg ctttactttg aaggggagcg tcaccacacc
     4681 tttcgtattt tgagagcggt caaaaatcgt tttggttcca ctaatgagat tgggattttt
     4741 gagatgcagt cgggcggctt ggttgaggta ctcaatccga gtcaagtttt cctagaagag
     4801 cgtttggatg gggcgactgg ttcctccatc gttgtaacca tggaagggac gcgtccgatt
     4861 ttggcggagg ttcaggcttt agtaacaccg accatgtttg gaaatgccaa gcgtactacg
     4921 acaggacttg attttaaccg tgctagcttg attatggctg ttttggaaaa acgggcaggg
     4981 cttctcttgc aaaatcagga tgcctatctc aaatctgctg gtggtgttaa attggatgaa
     5041 cctgccattg acttggctgt tgcagttgct attgcttcga gctacaaaga caaaccaact
     5101 aatcctcagg aatgttttgt cggagaactg ggcttgacag gagagattcg gcgcgtgaat
     5161 cgtattgagc aacgcatcaa cgaagctgct aaactgggct ttactaagat ttatgtacct
     5221 aagaattcct tgacaggaat cactctgcct aaggaaattc aggtcattgg cgtgacaacg
     5281 attcaggaag ttttgaaaaa ggtctttgca taatccgtga caaattctct taaaaatgat
     5341 aagataggag aaatatttga ctatcaaatt ttcaaggagg gaatcgtgtc gtattttgaa
     5401 cagtttatgc aagccaatca ggcttatgtt gccctacatg ggcagttaaa tctgccactt
     5461 aaacccaaaa caagagtagc tattgtgacc tgtatggact ctcgtctgca cgttgcgcaa
     5521 gctctgggct tggcacttgg ggatgctcat atcttgcgga atgcaggtgg tcgagtgact
     5581 gaagacatga ttcgttcgct agttatttcc cagcaacaaa tggggacaag agagattgtg
     5641 gtattgcacc atacagactg tggtgctcag acctttgaaa atgaaccttt tcaggagtat
     5701 ttaaaagagg aattaggtgt agatgtgtca gaccaggact tcttgccctt ccaagatata
     5761 gaagagagtg tacgcgagga tatgcaactg cttatcgagt ctcccctaat accagacgat
     5821 gtcattatct ctggtgctat ttacaatgtt gatacaggaa gtatgacagt cgtagaatta
     5881 taaatacttc atttagaaag aaagtgtatg aagaaaagca gtattttatt tatttttatt
     5941 ttattgctat gtattggttt acagtatgaa accatctact atacggacgg ttcgaggtca
     6001 ggtgcggaat atggactaat gggaatttct atctttctag ctctctttta catgattccg
     6061 gctctttatt ttctcttccg tattgggaaa aatgggaatt gccaaagaag gttttgattc
     6121 tgtctttatt gggagggatg ttcctttcag gatggttgtc tagttttgct aatacttata
     6181 tccatgattt actgggggtt cttttcccag atagtacatt tttaaatgcc tttgaaagtg
     6241 ctattgtggc tcctttggta gaagaaccct tgaaattatt gccacttgtt tttgttttgg
     6301 ctttgattcc tgtgcgaaaa ttaaaatctt tgtttttact tggaattgct tccggtttgg
     6361 gattccaaat gattgaggat attggttata ttcgtacgga tttgccagag ggctttgact
     6421 ttactatttc gcgaatttta gagcgtatca tctcaggaat tgcctctcac tggacttttt
     6481 caggtctagc tgtagtaggt gtttacttgc tttacagagc ctataaagga cagaaggttg
     6541 gcaagaaaca gggacttatt tttctaggtt tagccttggg aactcacttc ttgtttaact
     6601 ctccttttgt ggagttggaa acagagttgc ctttagcgat tccagtggtt acggctattg
     6661 ctctctatgg tttttatcat gcttattgct ttgttgagaa acacaatgag ttgatgacct
     6721 agaatatttt tcaaaagaat gatgcaaggg tacaaatatg gtgcccttct tttatttttg
     6781 tttaataaaa atagcataaa aatctagtta tccgcataaa aactggactt atcacacttt
     6841 atcaaggtca aaaccactca atttactact aatttactac ttatgaatga gctttgatac
     6901 gacgatttat ccttgaaaag tgaagatata aagatacttc caataaaatt tgaatattta
     6961 ataggtagac acttcaaaaa atgaggtgtc tattttttta cccgattttg aaaggaagtg
     7021 aacttatgaa aacaaaaaat caagaatcaa aaggtcgttc cccactcttt aagaccatca
     7081 aacattcatt cagccaataa aaaagaaagg ataggtaaaa atatggaact taaatttgtg
     7141 attcccaaca tggaaaaaac attcggcaat ttagaatttg ctggcgagga taaagtcgtt
     7201 cagcgaagaa tcaacggacg gctaactgtc ttatcaagaa gctataatct ctattctgat
     7261 gttcaaagag cagatgatat tgtggtggtg cttcctgctg aagctggcga aaaacatttc
     7321 ggctttgagg aacgtgtgaa gttagtcaat ccacgtatta ccgcagaggg ctacaaaatc
     7381 ggcactcgtg gttttacaaa ttacctttta catgctgacg acatgataaa agaataaaga
     7441 aagagaggaa aaatgatgag attagcaaat ggcattgtat tagataaaga cacgactttt
     7501 ggagaattga aattctctgc tctacgtcgt gaagtgagaa tccaaaatga agacgggtcg
     7561 gtttcagatg aaatcaagga acgtacctat gacttaaaat ccaaaggaca aggacgcatg
     7621 attcaagtaa gtattcctgc cagcgtgcct ttgaaagagt ttgattataa cgcacgggtg
     7681 gaacttatca atcccattgc ggacaccgtt gctactgcca cctatcaagg agcagatgtt
     7741 gactggtata tcaaggcaga cgatattgtg ctgacaaagg attctagttc attcaaagct
     7801 caaccacaag caaagaaaga accgacacaa gacaaatagt cgctaggtag aaaggagact
     7861 ttttcgcatg aaacagcgtg gtaaaaggat tcgcccatct ggtaaagatt tagtctttca
     7921 ttttacgata gcgtcactcc tgcctgtttt cctgctggtt gtcggactgt ttcatgtgaa
     7981 gacaatccag cagatcaact ggcaggattt taacctatca caagcagata agattgacat
     8041 tccctattta attatcagtt tcagtgtcgc aattcttatc tgcttgctgg tagcgtttgt
     8101 attcaaacgg gttcgctatg atacggttaa acaactttac caccgtcaaa aactggcaaa
     8161 gatgatactt gaaaacaagt ggtatgaatc tgaacaggtc aaaacagagg gtttctttaa
     8221 agatagtgct ggtcgtacaa aggaaaagat aacctacttc cctaaaatgt attatcgact
     8281 taaaaatggc ttgatacaga tacgggtgga aatcacgctg ggaaaatatc aagaccaact
     8341 cttacacttg gaaaagaaat tagagagtgg cttgtactgt gagctgacgg ataaagagtt
     8401 aaaggattcc tatgtggaat atactttgct ctatgacacc atagccagtc gtatttctat
     8461 tgatgaagta gaagctaaag atggtaaact tcgcttaatg aaaaacgtat ggtgggaata
     8521 tgataagctc cctcatatgt tgattgctgg tggtacaggt ggcggtaaaa cttactttat
     8581 actgacactg attgaagcct tgcttcatac agattcaaaa ctgtatattc ttgacccgaa
     8641 aaatgctgat cttgcggact taggttctgt gatggcaaat gtctactata gaaaagaaga
     8701 cttgctttct tgcattgaaa cattctatga agaaatgatg aaacgtagtg aggaaatgaa
     8761 gcagatgaag aactataaga ctggcaaaaa ttatgcttac ttaggtctcc cggcacactt
     8821 cttaatcttt gatgaatacg tcgctttcat ggaaatgctg ggaacaaaag aaaacaccgc
     8881 agttatgaat aagctgaaac agattgtcat gttaggtcgt caagctggct tctttctaat
     8941 actggcttgt caacgtccag acgcaaaata tttaggcgac ggaatccgtg atcagtttaa
     9001 tttcagagtg gctttaggtc gtatgtctga aatgggctat ggcatgatgt ttggcagtga
     9061 cgtacaaaag gatttcttct taaagcgaat caaaggtcgt ggctatgttg atgtaggaac
     9121 aagtgtcata tcagagtttt atactcccct tgtaccaaaa ggatatgatt tcttggagga
     9181 aattaaaaag ttatccaaca gcagacagtc cacgcaggcg acgtgcgaag cggaagtcgc
     9241 aggtgtggac tgatcttgct ggctggtgtg gcaatagcca cgccagcact taaccccccg
     9301 tatctaacag gggggtacaa atcgacagga aacagtcaaa aaaacattag aaaatccttt
     9361 ggttacaagg gatttacaaa atttcagcgt atgtcaaatg ggctttaaaa gttgacatac
     9421 gcctttttga ttggagggat ttttactgaa tgaacaaact tggttacagc atttaaaaga
     9481 aaaacgcttg gcttatggac tatctcaaaa ccgtttagct gttgcgactg gtattacaag
     9541 gcagtatcta agcgatattg aaacaggaaa agtcaagcca tcagaggatt tacagcagtc
     9601 cctttgggaa gctctggaac gcttcaatcc cgacgctccc cttgaaatgc tgtttgatta
     9661 tgtaagaatt cgctttccga caacagacgt acagcaggtg gtcgaaaaca tcttacaact
     9721 gaaactgtcc tattttcttc atgaggacta tggtttctat tcttattcag agcattatgc
     9781 tttaggcgac atattcgtcc tttgctccca tgaactggac aaaggagttc tggtggaatt
     9841 gaaaggtcgt gggtgcagac aatttgaaag ctatcttctg gcacaacaaa gaagctggta
     9901 tgagttcttt atggacgttt tggtggctgg cggtgtgatg aaacgccttg accttgccat
     9961 taacgataag acagggattt taaatatccc tgtactcact gaaaagtgcc aacaggaaga
    10021 atgtatctcc gtcttccgca gttttaaaag ctatcgcagt ggcgaactgg tacgcaaaga
    10081 ggaaaaggaa tgtatgggaa acaccctcta tatcggttca ttacaaagtg aagtttattt
    10141 ctgtatctat gaaaaggact acgagcagta caagaaaaat gatattccca ttgaagacgc
    10201 agaagtaaaa aaccgttttg agattcgatt gaaaaatgag cgtgcctatt atgcagtccg
    10261 tgatttactc gtctatgaca atccagagca taccgccttt aaaattatca atcggtatat
    10321 ccgttttgta gataaagacg attccaaacc tcgttctgat tggaaactga atgaagaatg
    10381 ggcttggttt attgggaaca atcgtgaacg attaaaacta accacaaaac cagagcctta
    10441 ctccttccaa aggacgctga actggctatc tcatcaagtt gccccgacct taaaggttgc
    10501 gattaaactt gatgaaatca accagacgca ggttgtaaaa gacattctcg accatgcgaa
    10561 actgacagac cgacacaagc agattttgaa gcaacagtca gtaaaagaac aggacgtgat
    10621 aacaacaaaa aaaggatatc tgtcaaccat accagttgac agatatccaa aaaaagatat
    10681 aatgggagat aagacggttc gtgttcgtgc tgacttgcac catatcataa aaatcgaaac
    10741 agcaaagaat ggcggaaacg taaaagaagt tatggaaata agacttagaa gcaaacttaa
    10801 gagtgtgttg atagtgcatt atcttaaaat tttgtataat aggaattgaa gttaaattag
    10861 atgctaaaaa tttgtaatta agaaggaggg attcgtcatg ttggtattcc aaatgcgtaa
    10921 tgtagataaa acatctactg ttttgaaaca gactaaaaac agtgattacg cagataaata
    10981 aatacgttag attaattcct accagtgact aatcttatga ctttttaaac agataactaa
    11041 aattacaaac aaatcgttta acttctgtat ttgtttatag atgtaatcac ttcaggagag
    11101 attacatgaa caaaaatata aaatattctc aaaacttttt aacgagtgaa aaagtactca
    11161 accaaataat aaaacaattg aatttaaaag aaaccgatac cgtttacgaa attggaacag
    11221 gtaaagggca tttaacgacg aaactggcta aaataagtaa acaggtaacg tctattgaat
    11281 tagacagtca tctattcaac ttatcgtcag aaaaattaaa actgaatact cgtgtcactt
    11341 taattcacca agatattcta cagtttcaat tccctaacaa acagaggtat aaaattgttg
    11401 ggaatattcc ttaccattta agcacacaaa ttattaaaaa agtggttttt gaaagccgtg
    11461 cgtctgacat ctatctgatt gttgaagaag gattctacaa gcgtaccttg gatattcacc
    11521 gaacactagg gttgctcttg cacactcaag tctcgattca gcaattgctt aagctgccag
    11581 cggaatgctt tcatcctaaa ccaaaagtaa acagtgtctt aataaaactt acccgccata
    11641 ccacagatgt tccagataaa tattggaagc tatatacgta ctttgtttca aaatgggtca
    11701 atcgagaata tcgtcaactg tttactaaaa atcagtttca tcaagcaatg aaacacgcca
    11761 aagtaaacaa tttaagtacc attacttatg agcaagtatt gtctattttt aatagttatc
    11821 tattatttaa cgggaggaaa taattctatg agtcgctttt ttaaatttgg aaagttacac
    11881 gttactaaag ggaatggaga taaattatta gatatactac tgacagcttc caagaagcta
    11941 aagaggtccc tagcgcctac ggggaatttg tatcgataag gggtacaaat tcccactaag
    12001 cgctcgggac cccttgtagg aaaatgtcct aagtgggata tctgtcaact ggtatggttg
    12061 actaaaaata cttcctacga aaatgtaggg ggtatttttt tacgaaaaaa tacaatcgat
    12121 tcttaaaaag aaaaattttt gattggcaaa accataacaa gttcgtttta gggttttgat
    12181 tttgcgattg atgccttcta aaggaccatt agagtattca aatttagcgc tatttaagac
    12241 atattttctg ttttgacgaa gggtttgaat agcagtatcc atttctgtat tggttttttg
    12301 gtagtctaag atggttgact ctagtaattc actattgcgc tcgtttaggg ctttcgtgat
    12361 atcttggtaa gtttggtata cttcagcgaa cttggaaaat ttactagtaa tgagatcaac
    12421 agcattttgg cgagtcatat attgtttaac gccgcgaaga aaaactactt cttcagggtg
    12481 aagatcttca gcttttttat ggaatagctt ccaatgtgac ttcataattt tatattcttg
    12541 gctctgttta tcaagttgct ttaggataga gatacgacaa ttgtccaaag cgcgaccagc
    12601 taattgtaca aggtggaagc gatcaataat gatattggca ttagggaaaa ggcgatagat
    12661 aaaactttga tattgagcat ttaaatcaat tacaactgat tgaacgcatt cgcgttcggc
    12721 ttttgaataa cgactttcaa aataatcaac aatggtaggt gatagacgat cctgtaactt
    12781 tgtgacaatt tggtgggttt cagcgtcaca acagataaag gacatcacag acttaattga
    12841 acgaaactcg tcaaaacata gatgcttagg caacttagcc acacgatagt gtggttccat
    12901 gcgctctaag attgttcgac gaacactgct aggagagcag tgacacattt cagcaataag
    12961 ctgaccagat aagcctttac gagctaaaag catgatttga tttttgagat cactggataa
    13021 ggtttgattt tctttggtta aattagtaat agcaccaaaa gtagtatggc atgatttaca
    13081 tttatagcgt tgtttacgaa gctctagttc atatcttctc ccatttaaac ttgccagtcg
    13141 tacatgagtt ttgcgaaagc catccttatt aactgtggga aagccacagt tacgacaacg
    13201 attaatcgga taagaaagag tagctgttat tagcgttata tactctttaa cagaatcgtt
    13261 gttgtgttca gcttcttcaa cagaaataat tttaatattt ttatctttaa ttccaagaat
    13321 atttaggata gaatcattat gggacatttg tttaaccttc tttcatgatt tttgtggtga
    13381 attgattgta taacgagggg acagcaaatg tcctcttttt tgtataaaaa aatctggcat
    13441 ggaatctcta tccataccag aaagtgtata ccccaaaaaa ataactcaaa tacaaattca
    13501 ttgaatatag agaggagaac atttttatga attttggaca aaacctttat aactggtttc
    13561 tatcaaacgc tcaatcactg gtgcttttag caatcgttgt gattggcttg tatcttggct
    13621 tcaagcgtga gtttagcaaa ctgattggct ttttaattat tgcgattatt gcggttggct
    13681 tagtcttcaa cgctgctgga gtaaaagaca ttttactaga gctattcaat cgcattattg
    13741 gtgcttaaat aaaaccgttc ttttgtggaa tataagtggt tttcttatgt tccgcaaagg
    13801 aatggtacac caaacgaagt gcggtaggga tttttgaatc tctacaaaga aaggacgtga
    13861 atatatggac gatatgcaag tctatattgc gaatttaggc aaatacaatg agggcgaatt
    13921 ggtcggtgcg tggtttacct ttcccattga ctttgaggaa gtcaaagaga aaatcggctt
    13981 gaatgatgaa tatgaggaat acgccattca tgactacgag ttacccttta cggttgacga
    14041 atacacttcc attggcgaac tcaatcgact atgggaaatg gtatcggaat tacccgaaga
    14101 attacaatcg gagctatctg ctctgctcac tcatttttca agcattgaag aactaagcga
    14161 acatcaagag gatattatca ttcattccga ttgtgatgat atgtatgacg tggcacgcta
    14221 ctacattgaa gaaacgggtg ctttaggcga agtaccagct agtcttcaaa actatattga
    14281 ttatcaagcc tatggtcggg atttagacct ttcaggaacg tttatctcaa ccaatcatgg
    14341 gatttttgaa atcgtctatt aaatctgtcg gtacattact actggcagat tttctatttt
    14401 acggggtggc tcaatcagct acccctattt tttatgaaag gattgattac atgaagaaaa
    14461 tacgaagcta taccagtatc tggtctgtgg aaaaggtact gtattctatc aatgatttta
    14521 gacttccgtt tcccataacc tttacgcaaa tgacatggtt tgtcgtgtca ctctttgcag
    14581 tgatgatact tggcaacttg ccccctcttt ccatgataga gggagcattt ctcaaatact
    14641 ttgggattcc tgtggctttc acatggttta tgtctacaaa aacttttgat ggtaaaaagc
    14701 cttatggatt tttgaagtct gtcattgctt atgcactgcg accaaagctg acctatgcag
    14761 gaaaaaaagt aacgcttggc agaaaccagc cacaagaagc cattacagca gttaggagtg
    14821 aattttatgg catatccaat taaatacatt gaaaacaatc tcgtctggaa taaagacggg
    14881 gaatgttatg cttactatga gcttgttcct tacaattact catttctaag tccagaacag
    14941 aaaatacaag tgcatgattc tttcagacag cttatcgcac aaaatcgtga tggcaaaatt
    15001 catgctttac aaatcagtac agaatccagc atacgttctg cacaagagcg ttccaaaaat
    15061 gaagtcactg gcaagctcaa agcggttgcc tatgacaaaa tcgaccaaca gacagacgct
    15121 ttaatatcca tgattggcga aaatcaagtg aactaccgtt tctttatcgg ctttaagttg
    15181 cttctcaacg atcaggagtt ttctatgaaa agtcttaccg ttgaagcaaa aaatgctttg
    15241 tctgattttg tctatgatgt gaaccataag ctgatgggcg attttgttag tatgagtaat
    15301 gatgaaatcc tgcgttttca gaagatggaa aagctcttag aaaataaaat ctctcgtcgt
    15361 ttcaaaatcc gcaggttaga taaggacgac ttcggctatc tgattgaaca cctttacgga
    15421 cagacaggca ctgcctatga agagtatgag taccatctat caaagaaaaa gctggataat
    15481 gaaacgctga ttaaatacta tgacttgatt aagcctactc gctgtttggt ggaagaaaaa
    15541 cagcgatatt tgaaaatcca gcaggaagat gaaaccgtct atgtagctta ctttaccatt
    15601 aacagcattg tcggagaact ggacttcccg tcctctgaaa tcttctacta ccagcaacag
    15661 caatttacat tcccgattga tacgtcaatg aatgtggaaa ttgtagcgaa tcgtaaagcc
    15721 ctatctactg tccgcaataa aaagaaagaa ctgaaagact tggataacca cgcttggcaa
    15781 agtgataatg aaaccagctc caatgtggcg gaagctctgg aaagtgtgaa tgagctggaa
    15841 accaatttag accaaagcaa ggaatctatg tacaagctgt cttatgtggt aagggtatca
    15901 gcaaatgatc ttgacgaact caaacgtcgt tgtaatgaag tgaaagattt ttatgacgat
    15961 ttaagcgtaa aactggtacg accatttggg gatatgctcg gcttacatga agaattttta
    16021 cctgccagca agcgttatat gaatgattat attcaatacg tgacctctga tttcctcgct
    16081 ggtttaggtt ttggtgctac tcaaatgctg ggggaaaatg aggggattta tgttggctac
    16141 agcttagata ctggacgcaa tgtctatctg aaacctgctc ttgccagtca aggggttaag
    16201 ggttcagtaa ccaatgcgtt agcgtcggct tttgttggtt cgctgggtgg tggtaaatcc
    16261 tttgcgaata accttatcgt ctattatgcg gtgctttatg gggcacaagc agtgattgta
    16321 gacccaaaag cagaacgtgg cagatggaaa gaaaccttgc cagagatttc ccatgaaatc
    16381 aatatcgtca ctctgacttc tgatgagaaa aacaaaggct tacttgaccc ttatgtgatt
    16441 atgaaaaatc ccaaagattc tgaatcactg gctattgata ttctgacatt ccttacgggg
    16501 atttcctctc gtgatgggga acgcttccca atccttagaa aagccattcg tgcagtaacc
    16561 aatagtgaag tacgagggtt gatgaaagtg attgaggaat tacgggttga gaatacgcca
    16621 ctaagtacca gtatagccga ccatatcgaa agttttacag actatgactt tgcacattta
    16681 ttattcagta atggttatgt ggagcagtct atcagcttag aaaaacaact gaacattata
    16741 caggttgcgg acttggtact tcccgacaag gaaacttcct ttgaggaata taccactatg
    16801 gagcttttat ccgttgctat gctgattgtc attagtacct ttgctttaga ctttatccat
    16861 acagaccgaa gcattttcaa gattgtagat ttagacgaag catggagctt tttacaggta
    16921 gcacaaggaa aaacactatc tatgaagctg gttcgggctg gtcgtgctat gaacgctggg
    16981 gtatatttcg tgacccaaaa tacagacgac ctcttagatg aaaaactgaa aaataacctc
    17041 ggcttaaaat ttgcatttcg ttccactgac cttaacgaga ttaaaaagac cttagccttt
    17101 tttggtgtag acccagagga cgaaaacaat cagaagcgat tgcgtgattt ggaaaacggg
    17161 caatgcctta tcagtgattt atatggtcgt gtcggtgtga tacagttcca ccctgtattt
    17221 gaagaactgc tccatgcctt tgataccaga ccacctgtgc gaaaagaggt gtaaatgtga
    17281 aaccatcaat agtaaacaga ataaaatcaa actggacgct gaaacgtcta ggtaaagtgg
    17341 caatgacagt ggctttcaca cttgtgattg ccatttttct tttagccatg ctgggaacgg
    17401 tggttcaagc tgcgggcttg gtagatgata cggtcaatgt ggcaaatgaa tacagccgat
    17461 acccacttga aaactatcaa ctggattttt atgtggataa tagctggggc tggcttccgt
    17521 ggaactggtc ggacgggatt ggaaaacagg tcatgtatgg actatatgcc attaccaatt
    17581 ttatttggac aatcagtttg tatgtttcca atgcgacagg ttacttagta caggaagcct
    17641 attccttaga cttcatttcc gctacagcag attccattgg taagaatatg cagaccttag
    17701 ctggtgtgag tgcaaacgga ttttcaacag agggtttcta tgttggattc ctcttactct
    17761 tgattttggt tcttggggtt tatgttgcct atacgggact gataaagaga gaaaccacaa
    17821 aggcaattca tgccattatg aattttgtgc tggtgtttat cctatcggct tcctttattg
    17881 cctacgctcc cgactacatt aaaaaaatca atgacttttc atcagacatc agtaatgcca
    17941 gtttatcact tggcacgaag attgtcatgc cccattccga tagtcaaggc aaggacagcg
    18001 tggacttaat cagagatagc ctgttttcca tacaggttca gcaaccgtgg ctactgcttc
    18061 aatacaacag ttcagacatt gaaagtatcg gtattgaccg tgtggaaagc ctgctctcca
    18121 ccagcccaga ttccaacaat ggcgaagaca gagaaaaaat tgttgcggaa gaaattgaag
    18181 acagaagcaa taccaatcta accattacaa agaccattaa ccgtttaggt acagtcttct
    18241 tcctatttgt cttcaatatt gggatttcca tatttgtatt cctattaaca ggaatcatga
    18301 ttttctcgca ggtacttttt atcatctatg ctatgtttct gcctgtgagc tttattttaa
    18361 gcatgattcc atcatttgat ggtatgtcaa aacgagccat aacaaagctc tttaatacca
    18421 ttttgacacg agctggaatc acattgatta ttacgacagc atttagtatt tcaaccatgc
    18481 tctatacctt atcggctggt tatccgttct ttttgattgc ttttctacag attgtgacct
    18541 ttgcaggaat ctacttcaag ctgggcgatt taatgagtat gttttctcta cagagtaacg
    18601 attctcaaag tgtgggaagt cgtgtgatga gaaaacctcg tatgcttatg cacgctcaca
    18661 tgcaccgtct acagcggaaa cttggacgtt ccatgactac tctaggggct gggtctgcca
    18721 ttgttacagg taaaaaagga cagtcgggtt cggggagttc tgcaaggaca caagcagatc
    18781 actcccgacc agacggaaag gaaaaatcaa cacttggaaa acgtatcggt caaaccatcg
    18841 gtacagtagc tgataccaaa gacagaatgg tagacactgc tagtggtttg aaagaacagg
    18901 ttaaagattt gccgaccaat gcaagatatg cagtatatca aggaaaatcc aaagtaaaag
    18961 agaatgtccg tgatttaacc agtagtattt ctcaaaccaa agcggacaga gccagtggac
    19021 gcaaggaaca gcaggaacaa aggcgaaaaa ccattgcgaa gcgtcgctct gaaatggaac
    19081 aggtcaaaca gaaaaaacag cctgcttctt ctgttcatga aagaccgact acaagacaag
    19141 aacaatatca tgatgaacag acctcaaaac agtctaatat tcagacttca tataaggaat
    19201 ctcaacaagc caaacaagag cgtccagcag ttaagtccga tttttcaagt ccaaaagtgg
    19261 aacgccaagg caataccgtt caagaaaaaa ccgttcaaaa gccagcaact tcaaccacta
    19321 cagcagatag aacttcacaa cgtccaatca caaaagaacg tccgtctact gttcaaagag
    19381 taccactaca aaatacaaga agtagaccac caatcaaaac cgccaccatt aagaaagtcg
    19441 gtaagaaacc atgaagttga aaactttagt gattggtggt tctggattat tcttgatggt
    19501 cttctcactg cttctgtttg ttgccatttt attttcagat gaacaggaca gcggaatttc
    19561 caatattcat tatggaggtg tgaatgtttc cgcagaagtg ctggctcata agcctatggt
    19621 agaaaaatat gccaaagaat atggcgttga agaatatgtc aacatacttc ttgcgattat
    19681 acaggtggaa tcgggcggta ctgcggaaga tgttatgcag tcctcggaat ccctcggtct
    19741 tccacctaat tcattgagta cagaagaatc cattaagcaa ggtgtgaagt atttcagtga
    19801 attattagcc agtagcgaaa ggctcagtgt agatttagaa tcggttatcc agtcctacaa
    19861 ttatggtggt ggtttcttag ggtatgtggc taatcgtgga aataaatata cctttgaact
    19921 ggctcaaagt ttctcaaaag agtattcagg tggcgaaaaa gtgtcttacc ccaatcccat
    19981 agccatacct atcaatgggg gctggcgata caactatggc aatatgtttt atgtgcaact
    20041 ggtaacgcag tatcttgtca caacagagtt tgatgatgat acggtacaag ccatcatgga
    20101 cgaagcactg aaatatgagg gctggcgata cgtttacggt ggagcttccc cgactacttc
    20161 ttttgattgt agcggactga cacaatggac gtatggaaaa gctggaatta acttaccacg
    20221 aaccgcacaa cagcaatatg atgtgaccca gcatatccca ctatcggaag cacaagctgg
    20281 cgatttggtt ttctttcatt ctacctataa cgctggctct tatattactc atgttgggat
    20341 ataccttggc aataaccgta tgtttcatgc aggcgaccca atcggttatg ccgacttaac
    20401 aagcccctac tggcaacagc atttagtggg agcaggacga atcaaacaat gagaaaggaa
    20461 gatttaatga tgaaatttag aaaaaatcag aataaagaaa aacagatacc aaaggaaaag
    20521 aaacctcgtg tctataaggt caatcctcat aaaaaggttg tgattgcctt gtgggtactt
    20581 ttagggctta gtttcagctt tgcgatattc aagcacttta cagctataga tactcatact
    20641 attcacgaaa caactatcat agaaaaggaa tacgttgata ctcatcatgt agaaaatttt
    20701 gtagagaact ttgcgaaagt ctactattca tgggagcaat ccgataagtc cattgataat
    20761 cgaatggaaa gtctaaaagg ctatctgaca gatgaacttc aagctctcaa tgttgataca
    20821 gtacgcaaag atattcctgt atcgtcttct gtaagaggat ttcagatatg gacggtagag
    20881 ccaactggcg acaatgagtt taatgtaacc tacagtgtag accagctcat tacagaggga
    20941 gaaaatacaa agaccgtcca ctctgcttat atagtgagtg tctatgtaga tggttctgga
    21001 aatatggtac tggttaagaa tccgaccatt accaacatac ctaagaaatc aagttataaa
    21061 ccaaaagcca ttgaaagtga ggggacggtt gattccatta caaccaatga aatcaatgag
    21121 tttttaacga cgttcttcaa gctctatcct acagcgacag ccagtgaact ttcctactat
    21181 gtgaatgacg ggatattaaa accaatcgga aaagagtaca tctttcaaga actggtaaat
    21241 cctattcaca atcgtaagga taatcaagtc acggtatcgc tgacagtgga gtatatcgac
    21301 cagcagacca aagcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt
    21361 aattggaaga ttgtaaaata acaaatattg gtacatgatt acagatactt tgtaatcatg
    21421 tactcttttt gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt
    21481 taagtgacta tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc
    21541 aatttgatag cgggaacaaa taattagatg tcctttttta ggagggctta gttttttgta
    21601 cccagtttaa gaataccttt atcatgtgat tctaaagtat ccagagaata tctgtatgct
    21661 ttgtatacct atggttatgc ataaaaatcc cagtgataaa agtatttatc actgggattt
    21721 ttatgccctt ttgggttttt gaatggagga aaatcacatg aaaattatta atattggagt
    21781 tttagctcat gttgatgcag gaaaaactac cttaacagaa agcttattat ataacagtgg
    21841 agcgattaca gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt
    21901 agaacgtcag agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac
    21961 gaaggtgaac atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc
    22021 attatcagtt ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca
    22081 aactcgtata ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa
    22141 taagattgac caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact
    22201 ttctgccgaa attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa
    22261 ctttaccgaa tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa
    22321 atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa caagaggaaa gcataagatt
    22381 tcataattgt tccctgttcc ctgtttatca cggaagtgca aaaaacaata tagggattga
    22441 taaccttata gaagtgatta cgaataaatt ttattcatca acacatcgag gtccgtctga
    22501 actttgcgga aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatat
    22561 acgcctttat agtggagtac tacatttacg agattcggtt agagtatcag aaaaagaaaa
    22621 aataaaagtt acagaaatgt atacttcaat aaatggtgaa ttatgtaaga ttgatagagc
    22681 ttattctgga gaaattgtta ttttgcaaaa tgagtttttg aagttaaata gtgttcttgg
    22741 agatacaaaa ctattgccac agagaaaaaa gattgaaaat ccgcaccctc tactacaaac
    22801 aactgttgaa ccgagtaaac ctgaacagag agaaatgttg cttgatgccc ttttggaaat
    22861 ctcagatagt gatccgcttc tacgatatta cgtggattct acgacacatg aaattatact
    22921 ttctttctta gggaaagtac aaatggaagt gattagtgca ctgttgcaag aaaagtatca
    22981 tgtggagata gaactaaaag agcctacagt catttatatg gagagaccgt taaaaaatgc
    23041 agaatatacc attcacatcg aagtgccgcc aaatcctttc tgggcttcca ttggtttatc
    23101 tgtatcaccg cttccgttgg gaagtggaat gcagtatgag agctcggttt ctcttggata
    23161 cttaaatcaa tcatttcaaa atgcagttat ggaagggata cgctatggtt gcgaacaagg
    23221 attatatggt tggaatgtga cggattgtaa aatctgtttt aagtatggct tatactatag
    23281 ccctgttagt accccagcag attttcggat gcttgctcct attgtattgg aacaagtctt
    23341 aaaaaaagct ggaacagaat tgttagagcc atatcttagt tttaaaattt atgcgccaca
    23401 ggaatatctt tcacgagcat acaacgatgc tcctaaatat tgtgcgaaca tcgtagacac
    23461 tcaattgaaa aataatgagg tcattcttag tggagaaatc cctgctcggt gtattcaaga
    23521 atatcgtagt gatttaactt tctttacaaa tggacgtagt gtttgtttaa cagagttaaa
    23581 agggtaccat gttactaccg gtgaacctgt ttgccagccc cgtcgtccaa atagtcggat
    23641 agataaagta cgatatatgt tcaataaaat aacttagtgt attttatgtt gttatataaa
    23701 tatggtttct tgttaaataa gatgaaatat tttttaataa agatttgaat taaagtgtaa
    23761 aggaggagat agttattata aactacaagt ggatattgtg tcctgtatgt ggaaataaaa
    23821 cacgattaaa gataagggaa gatactgaat taaaaaaatt ccccctctat tgtccgaaat
    23881 gcagacaaga aaatttaatt gaaataaagc agttcaaagt aactgtgatt acagagccag
    23941 acgcaaagac gcagagccga taaaatgaga ttaatacaat ctcattttat cggctctttc
    24001 cgttatgtat ggattctttt aattagtctt cgatgtttct tgcttcgttg ataccgctgg
    24061 ctaaagattc cattaaggat agttctttgt ctgtaaagct atccatgtat ttctctatct
    24121 gtaatcgtcg ggtgcttttt accaagttat tagcaggtaa gaaaaattca tcaacggaaa
    24181 catgaagtaa cgatacaagg tcataaagaa cttgtatgct ggggtgttgc cctttatttt
    24241 caatattagt taagtaccgt gggtcaattt caatcaatgc tcccacttgt tcacgagtta
    24301 aacctcgttt caatcgagct tctttaatgg ctaaaccaaa ggctctaaaa tcatatttat
    24361 cttctttttt acgcatagta gaccacctct atacatttta ttgttcctac tgaattaaaa
    24421 acaggtatag aaaaacgtgt tatatggttt ataggtttat atttaataaa aagcactact
    24481 aaacgccaat aaaaaaaacc gttatatggt agtgctattt acgctgttaa aatattgtat
    24541 attacttcca aatggcggtt tgttggaggt caacgtcgcc atgaagtaca tcatatacaa
    24601 taaatttcct tacattgggt tcttgtcaaa aaaagtcgtc tatctgcaat agataagtac
    24661 gtccaccaat gtggttttat aaatcatata gatagaataa cagaagcatg taaacagaga
    24721 aataaatctg tttatatgct tttttggcta ttcagaactt ttttacaaag tttatttatc
    24781 agtaatgcaa caaatccccc tttcacattg ggactaagag tgaaaggaga taaacgagca
    24841 aggctcactt cctttcctag acagaaaggg ggtgagaaac atgaaaccat cttcttttca
    24901 gaccacaata gaaaatcagt ttgactatat ctgtaaacgt gctatggaag acgagcgaaa
    24961 gaattatatg ctttatcttt caaggattgc aaagcgtgag gtgtcctttt cggatgttgg
    25021 cgattatctt gttagccagt ttgcgacaac agataactat tcaactgact ttcagatttt
    25081 tacactcaat gggttatcag taggcgttga aaatgatttg ttgagtgaag cattacgtga
    25141 gttgccagac aagaaacgtg aaattctact gctgttttac tttatggaca tgagcgattc
    25201 agaaattgca gacctgttga aattgaaccg ttctactgtc tatcggcata gaaccagtgg
    25261 actagcctta attaaaaagt ttatggagga atttgaagaa tgaaaacaca atatcctatg
    25321 attccctttc ctctcattgt aaaggcaaca gatggcgata ccgaagcgat taaccagatt
    25381 ctacatcatt acagagggta cataacgaag cgttccctac gacttatgaa agatgaatat
    25441 ggcaatcaaa gtatggtcgt tgatgaagtc ttacgtggaa gaatggaaac cagactgatt
    25501 acaaagattt tgtcatttga aattaagtaa tatcctctct cctttcgtgg aagcgtgcta
    25561 aaccattcca cgcttcccga acagggaggt ttgttattcc accaaagcat attgagcttt
    25621 caatgtgttt tgataggcta acgagccatt gttctttgaa aactgaataa aagtaatcga
    25681 atacgtttcg ataagaaaag agccaacgga actaaccgcc atgacctatc ttataaagat
    25741 agcgagcgat tcatgttagt gatccgagaa gcaatcttta gcaggattgc ctgcaacgac
    25801 attcttatcg tgataatgat actcccatac agtcaatagt ccgagcgtga taaaaccgtc
    25861 gcaggcaatg agtatggcta catgagaacc atgcaggggt ggaactcccg tgagctttgc
    25921 taaagctgtt cgattgctgg taaaacaact tttatgaaat ccaaataagt gatttggaaa
    25981 ggaggatttt atgaagcaga ctgacattcc tatttgggaa cgttataccc taaccattga
    26041 agaagcgtca aaatattttc gtattggcga aaacaagcta cgacgcttgg cagaggaaaa
    26101 taaaaatgca aattggctga ttatgaatgg caatcgtatt cagattaaac gaaaacaatt
    26161 tgaaaaaatt atagatacat tggacgcaat ctagcgtcgc caaagggtct tgtatatgat
    26221 aaaatagtat taagtcgtat caaggctctt tccataaagg aaaggagcaa atgccatgtc
    26281 agaaaaaaga cgtgacaata aaggtcgaat cttaaagact ggagagagcc aacgaaaaga
    26341 cggaagatac ttatacaaat atatagattc atttggagaa ccgcaatttg tttactcgtg
    26401 gaaacttgtg gctacagacc gagtaccagc aggaaagcgt gattgtatct cacttagaga
    26461 gaaaatcgca gagttacaga aagacattca tgatggtatt gatgttgtag gaaagaaaat
    26521 gacactctgc cagctttacg caaaacagaa cgctcaaaga ccaaaggtta gaaaaaacac
    26581 tgaaactgga cgcaaatatc ttatggatat tttgaagaaa gacaagttag gtgtaagaag
    26641 tattgacagt attaagccat cagacgctaa agaatgggct attagaatga gtgaaaatgg
    26701 ttatgcttat caaaccatca ataactacaa acgttcttta aaggcttcat tctatattgc
    26761 tatacaagat gattgtgttc ggaagaatcc atttgacttt caactgaaag cagttcttga
    26821 tgatgatact gtccctaaga ccgtactaac agaagaacag gaagaaaaac tgttagcctt
    26881 tgcaaaagct gataaaacct acagcaaaaa ttatgatgaa attctgatac tcttaaaaac
    26941 aggtcttcgt atttcagagt ttggtggttt gacacttcca gatttagatt ttgagaatcg
    27001 tcttgtcaat atagaccatc agctattgag agatactgaa attgggtact acattgaaac
    27061 accaaagacc aaaagtggcg aacgtcaagt tcctatggtt gaagaagcct atcaagcatt
    27121 taagcgagtg ttagcgaatc gaaagaatga taagcgtgtt gagattgatg gatatagtga
    27181 tttcctcttt cttaatagaa agaactatcc aaaagtggca agtgattaca acggcatgat
    27241 gaaaggtctt gttaagaaat acaataagta taacgaggat aaattgccac acatcactcc
    27301 acatagtttg cgacatacat tctgtaccaa ctatgcaaat gcaggaatga atccaaaggc
    27361 attacagtac attatgggac atgctaatat agccatgacg ctgaactatt acgcacatgc
    27421 aacattcgat tctgcaatgg cagaaatgaa acgcttgaat aaagagaagc aacaggagcg
    27481 tcttgttgct tagtagtaca aatgaattta ctacttattt accacttctg acagctaaga
    27541 catgaggaaa tatgcaaaga aacgtgaagt atcttcctac agtaaaaata ctcgaaagca
    27601 catagaataa ggctttacga gcatttaaga aaatataaaa agataattag aaatttatac
    27661 tttgtttgat tgaaaaatag tgcaaaaagc gctacaatgg tagatggaaa atcttgtgaa
    27721 aagcacaagt tatacatata taccggagga aatcatgtct ttttctgatt taaagctgtt
    27781 tgccctttct tctaataaag aattggcaga acgtgtggcg caggagattg ggatagagtt
    27841 ggggaaatca agtgttcgcc aattttcaga tggagagatt caggtcaaca ttgaagaatc
    27901 aatccgtggg aaacacgtct ttatcttaca atcaactagt tcgcctgtaa atgacaatct
    27961 gcttgaaatt ttgattatgg tagatgcttt gaagcgtgcg agtgcagaat ctgttaatgt
    28021 tgtcatgcct tactatgggt atgcacgtca ggatagaaag gcgagagcgc gtgagccaat
    28081 cacttcaaaa cttgtcgcaa atatgcttga agtagctgga gtggatcgtt tattgaccat
    28141 cgacttgcat gctgcgcaaa ttcaaggatt ctttgatatt cctgtggatc atttgatggg
    28201 tgctcctctg attgcagatt attttgagcg tcgtggtatg gttggttctg actatgtggt
    28261 tgtcagcccg gaccatggag gggtgactcg tgctcgtaag ttggcagaat ttttgaaaac
    28321 atctatcgct attattgata aacgtcgtag cgttgataag atgaatacta gtgaagttat
    28381 gaacatcatc ggtaaggttg aaggcaagac ttgtatcttg attgatgata tgattgatac
    28441 cgctggaacg atttgtcatg cggcagatgc tcttgcggaa gctggtgctg ttgaagtcta
    28501 tgcaagctgt acgcacccag ttctttctgg tcctgctacg gacaatatcc aaaaatcagc
    28561 tattaagaaa ttggttgttt tggataccat ctatctgcca gaagagcgtt tgattgataa
    28621 gattgagcag atttcaatcg ctcatctcct aggggatgct atcgtacgta ttcatgaaaa
    28681 acgaccactt tctccacttt tcgatattga gaaaaaaatt taatgaccaa gcctgagatg
    28741 attctcaggt tttttcgtct tttttccgaa taaatagata gtagcggtga atctagtaaa
    28801 gctagattta aaactgtgat ataataaaaa gagaagaaat atgactgtac gtcatcagaa
    28861 gtttcagcga ccatcatttt tgaacagtga tagcacttga atcgacgctt tctaaggaga
    28921 attctagtag gtataccagt cgtttcaaga taaggaattt tagaaggttt tt
//
